ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min ribonucleoprotein_complex GO:0030529 12133 569 49 21 9264 49 2 false 1.9304207085684281E-13 1.9304207085684281E-13 0.0 multi-organism_cellular_process GO:0044764 12133 634 49 19 9702 48 2 false 4.549583858287473E-11 4.549583858287473E-11 0.0 macromolecular_complex GO:0032991 12133 3462 49 36 10701 49 1 false 4.077235295350408E-9 4.077235295350408E-9 0.0 reproduction GO:0000003 12133 1345 49 23 10446 49 1 false 5.742686620548656E-9 5.742686620548656E-9 0.0 reproductive_process GO:0022414 12133 1275 49 22 10446 49 2 false 1.2660504377917569E-8 1.2660504377917569E-8 0.0 cellular_metabolic_process GO:0044237 12133 7256 49 48 10007 48 2 false 1.906564889030747E-7 1.906564889030747E-7 0.0 cytosol GO:0005829 12133 2226 49 32 5117 38 1 false 2.561340617951749E-7 2.561340617951749E-7 0.0 multi-organism_process GO:0051704 12133 1180 49 19 10446 49 1 false 5.937176396461373E-7 5.937176396461373E-7 0.0 macromolecule_catabolic_process GO:0009057 12133 820 49 19 6846 48 2 false 9.712421681176787E-7 9.712421681176787E-7 0.0 mRNA_metabolic_process GO:0016071 12133 573 49 18 3294 33 1 false 1.2867889763924517E-6 1.2867889763924517E-6 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 49 17 6457 48 3 false 3.077499061752206E-6 3.077499061752206E-6 0.0 regulation_of_molecular_function GO:0065009 12133 2079 49 24 10494 49 2 false 4.203564757285962E-6 4.203564757285962E-6 0.0 catabolic_process GO:0009056 12133 2164 49 28 8027 48 1 false 4.4462149025061114E-6 4.4462149025061114E-6 0.0 organelle_part GO:0044422 12133 5401 49 40 10701 49 2 false 5.960780469716132E-6 5.960780469716132E-6 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 49 28 7502 48 2 false 6.137606099520512E-6 6.137606099520512E-6 0.0 translational_elongation GO:0006414 12133 121 49 8 3388 31 2 false 8.3139112742783E-6 8.3139112742783E-6 5.332026529203484E-226 regulation_of_response_to_stimulus GO:0048583 12133 2074 49 23 7292 36 2 false 9.868604625283044E-6 9.868604625283044E-6 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 49 47 7569 48 2 false 9.929494473960868E-6 9.929494473960868E-6 0.0 cellular_process_involved_in_reproduction GO:0048610 12133 469 49 11 9699 48 2 false 1.334792475059624E-5 1.334792475059624E-5 0.0 cellular_catabolic_process GO:0044248 12133 1972 49 27 7289 48 2 false 1.7776056211700727E-5 1.7776056211700727E-5 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 49 28 10701 49 1 false 1.822152910059082E-5 1.822152910059082E-5 0.0 ribosomal_subunit GO:0044391 12133 132 49 7 7199 48 4 false 2.3389917449088755E-5 2.3389917449088755E-5 2.5906239763169356E-285 translational_initiation GO:0006413 12133 160 49 7 7667 43 2 false 2.5896875145200984E-5 2.5896875145200984E-5 0.0 negative_regulation_of_molecular_function GO:0044092 12133 735 49 13 10257 49 2 false 2.7691116727050907E-5 2.7691116727050907E-5 0.0 regulation_of_signaling GO:0023051 12133 1793 49 21 6715 35 2 false 3.333551395618426E-5 3.333551395618426E-5 0.0 cytosolic_part GO:0044445 12133 178 49 8 5117 38 2 false 3.6625887173581875E-5 3.6625887173581875E-5 0.0 metabolic_process GO:0008152 12133 8027 49 48 10446 49 1 false 3.801442378711719E-5 3.801442378711719E-5 0.0 nucleus GO:0005634 12133 4764 49 39 7259 42 1 false 3.8149756271029135E-5 3.8149756271029135E-5 0.0 regulation_of_signal_transduction GO:0009966 12133 1603 49 21 3826 26 4 false 5.704965111256883E-5 5.704965111256883E-5 0.0 regulation_of_cell_communication GO:0010646 12133 1796 49 21 6469 35 2 false 6.274824718467474E-5 6.274824718467474E-5 0.0 RNA_catabolic_process GO:0006401 12133 203 49 9 4368 40 3 false 6.590883525722197E-5 6.590883525722197E-5 0.0 ribosome GO:0005840 12133 210 49 8 6755 46 3 false 7.198647835213886E-5 7.198647835213886E-5 0.0 receptor_signaling_protein_activity GO:0005057 12133 339 49 8 1070 8 1 false 9.589154319518642E-5 9.589154319518642E-5 2.5248591221043436E-289 neurotrophin_signaling_pathway GO:0038179 12133 253 49 9 2018 18 2 false 1.1615869327887926E-4 1.1615869327887926E-4 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 49 43 8027 48 1 false 1.1628819397824657E-4 1.1628819397824657E-4 0.0 translational_termination GO:0006415 12133 92 49 7 513 9 2 false 1.2890955306237923E-4 1.2890955306237923E-4 3.4634519853301643E-104 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 49 31 10446 49 1 false 1.427098944526397E-4 1.427098944526397E-4 0.0 phosphoprotein_binding GO:0051219 12133 42 49 4 6397 42 1 false 1.4998537492643543E-4 1.4998537492643543E-4 2.265958128878875E-109 structural_constituent_of_ribosome GO:0003735 12133 152 49 7 526 7 1 false 1.5224406638528182E-4 1.5224406638528182E-4 1.18011379183299E-136 single-organism_transport GO:0044765 12133 2323 49 24 8134 43 2 false 1.5829056028247347E-4 1.5829056028247347E-4 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 49 43 7341 48 5 false 1.5874819107987022E-4 1.5874819107987022E-4 0.0 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 49 20 4597 29 2 false 1.847095420136993E-4 1.847095420136993E-4 0.0 innate_immune_response GO:0045087 12133 626 49 12 1268 12 2 false 1.9863858721973603E-4 1.9863858721973603E-4 0.0 cellular_localization GO:0051641 12133 1845 49 21 7707 42 2 false 2.126202989592788E-4 2.126202989592788E-4 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 49 21 5462 44 2 false 2.3253191537922306E-4 2.3253191537922306E-4 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 49 21 5528 44 2 false 2.4376048963663493E-4 2.4376048963663493E-4 0.0 nuclear_part GO:0044428 12133 2767 49 30 6936 45 2 false 2.454056802589856E-4 2.454056802589856E-4 0.0 regulation_of_protein_metabolic_process GO:0051246 12133 1388 49 21 5563 41 3 false 2.5225597628624315E-4 2.5225597628624315E-4 0.0 positive_regulation_of_metabolic_process GO:0009893 12133 1872 49 22 8366 48 3 false 2.621445730816609E-4 2.621445730816609E-4 0.0 heterocycle_catabolic_process GO:0046700 12133 1243 49 21 5392 44 2 false 2.714803089799493E-4 2.714803089799493E-4 0.0 viral_transcription GO:0019083 12133 145 49 7 2964 28 3 false 2.8865876204685716E-4 2.8865876204685716E-4 1.0927707330622845E-250 aromatic_compound_catabolic_process GO:0019439 12133 1249 49 21 5388 44 2 false 2.9470307287577654E-4 2.9470307287577654E-4 0.0 establishment_of_localization GO:0051234 12133 2833 49 25 10446 49 2 false 3.1358808415801775E-4 3.1358808415801775E-4 0.0 RNA_processing GO:0006396 12133 601 49 14 3762 34 2 false 3.7357101883028337E-4 3.7357101883028337E-4 0.0 macromolecular_complex_subunit_organization GO:0043933 12133 1256 49 20 3745 31 1 false 3.8938160160344095E-4 3.8938160160344095E-4 0.0 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 49 43 7451 48 1 false 3.964904793174589E-4 3.964904793174589E-4 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway_involved_in_phagocytosis GO:0002433 12133 72 49 4 500 4 2 false 3.998358162106584E-4 3.998358162106584E-4 6.2427882790248544E-89 heterocycle_metabolic_process GO:0046483 12133 4933 49 43 7256 48 1 false 4.4792840922386736E-4 4.4792840922386736E-4 0.0 positive_regulation_of_biological_process GO:0048518 12133 3081 49 26 10446 49 2 false 4.547110489978316E-4 4.547110489978316E-4 0.0 protein_targeting GO:0006605 12133 443 49 12 2378 24 2 false 4.6457920605520655E-4 4.6457920605520655E-4 0.0 negative_regulation_of_binding GO:0051100 12133 72 49 4 9054 46 3 false 4.661700790690383E-4 4.661700790690383E-4 1.0408990583833388E-181 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 49 43 7256 48 1 false 4.6964497823142015E-4 4.6964497823142015E-4 0.0 organelle GO:0043226 12133 7980 49 46 10701 49 1 false 4.939284423933433E-4 4.939284423933433E-4 0.0 protein_metabolic_process GO:0019538 12133 3431 49 34 7395 48 2 false 5.137512590870201E-4 5.137512590870201E-4 0.0 intracellular_organelle_part GO:0044446 12133 5320 49 40 9083 49 3 false 5.18393869799256E-4 5.18393869799256E-4 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 49 38 6846 48 2 false 5.266766272453759E-4 5.266766272453759E-4 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 49 47 7451 48 1 false 5.436521665141135E-4 5.436521665141135E-4 0.0 signal_transduction_by_phosphorylation GO:0023014 12133 307 49 8 3947 26 2 false 5.51240343158381E-4 5.51240343158381E-4 0.0 negative_regulation_of_dephosphorylation GO:0035305 12133 6 49 2 562 4 3 false 5.65491097887146E-4 5.65491097887146E-4 2.3471675405869638E-14 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 49 21 4878 43 5 false 5.974069131004661E-4 5.974069131004661E-4 0.0 positive_regulation_of_cellular_process GO:0048522 12133 2811 49 25 9694 48 3 false 6.327017110836621E-4 6.327017110836621E-4 0.0 cellular_component_disassembly GO:0022411 12133 351 49 8 7663 44 2 false 7.449421833808193E-4 7.449421833808193E-4 0.0 positive_regulation_of_molecular_function GO:0044093 12133 1303 49 15 10257 49 2 false 7.76911480231433E-4 7.76911480231433E-4 0.0 response_to_chemical_stimulus GO:0042221 12133 2369 49 22 5200 29 1 false 8.720348957950324E-4 8.720348957950324E-4 0.0 protein_binding GO:0005515 12133 6397 49 42 8962 46 1 false 9.667524093953349E-4 9.667524093953349E-4 0.0 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 49 43 7275 48 2 false 0.001035526442097635 0.001035526442097635 0.0 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 49 19 5303 41 3 false 0.0010811885253437748 0.0010811885253437748 0.0 regulation_of_catalytic_activity GO:0050790 12133 1692 49 18 6953 37 3 false 0.0011101342645512997 0.0011101342645512997 0.0 enzyme_binding GO:0019899 12133 1005 49 15 6397 42 1 false 0.0011812620463320393 0.0011812620463320393 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 49 33 8962 46 1 false 0.0012260969804217018 0.0012260969804217018 0.0 localization GO:0051179 12133 3467 49 27 10446 49 1 false 0.0012662076042767173 0.0012662076042767173 0.0 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 49 14 5778 32 3 false 0.0012717047249864426 0.0012717047249864426 0.0 cellular_macromolecule_localization GO:0070727 12133 918 49 16 2206 21 2 false 0.001328103341998055 0.001328103341998055 0.0 regulation_of_protein_catabolic_process GO:0042176 12133 150 49 7 1912 23 3 false 0.0013345472010336814 0.0013345472010336814 1.3832082048306078E-227 viral_reproductive_process GO:0022415 12133 557 49 19 783 19 2 false 0.0014143170486502757 0.0014143170486502757 1.4346997744229993E-203 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 49 21 7638 48 4 false 0.0014154649138114598 0.0014154649138114598 0.0 intracellular_transport GO:0046907 12133 1148 49 18 2815 25 2 false 0.0015059469573462528 0.0015059469573462528 0.0 organic_cyclic_compound_binding GO:0097159 12133 4407 49 33 8962 46 1 false 0.001553846227473754 0.001553846227473754 0.0 spliceosomal_complex GO:0005681 12133 150 49 7 3020 36 2 false 0.0016022489760099618 0.0016022489760099618 2.455159410572961E-258 cytoplasmic_part GO:0044444 12133 5117 49 38 9083 49 2 false 0.001615386677403746 0.001615386677403746 0.0 regulation_of_binding GO:0051098 12133 172 49 5 9142 46 2 false 0.00163357463921581 0.00163357463921581 0.0 Prp19_complex GO:0000974 12133 78 49 4 2976 21 1 false 0.0018622181463774218 0.0018622181463774218 3.570519754703887E-156 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 49 16 4044 37 3 false 0.001903922709243784 0.001903922709243784 0.0 multi-organism_reproductive_process GO:0044703 12133 707 49 19 1275 22 1 false 0.0020892483941137375 0.0020892483941137375 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 49 7 6813 39 2 false 0.002202535451478999 0.002202535451478999 0.0 activation_of_MAPKK_activity GO:0000186 12133 64 49 5 496 9 3 false 0.002572113027092499 0.002572113027092499 2.7437381948522894E-82 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 49 32 8688 48 3 false 0.0027371870222425198 0.0027371870222425198 0.0 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 49 9 587 10 2 false 0.0027396571255131853 0.0027396571255131853 2.854325455984618E-173 cellular_protein_metabolic_process GO:0044267 12133 3038 49 34 5899 47 2 false 0.002835271726116412 0.002835271726116412 0.0 RNA_binding GO:0003723 12133 763 49 14 2849 26 1 false 0.002973373087164829 0.002973373087164829 0.0 response_to_growth_factor_stimulus GO:0070848 12133 545 49 12 1783 19 1 false 0.003205565041256669 0.003205565041256669 0.0 pseudopodium GO:0031143 12133 13 49 2 976 7 1 false 0.003315007048073046 0.003315007048073046 9.253153669613935E-30 regulation_of_transferase_activity GO:0051338 12133 667 49 11 2708 20 2 false 0.0033620796364065572 0.0033620796364065572 0.0 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 49 8 1239 17 2 false 0.0036154094116253553 0.0036154094116253553 4.427655683668096E-244 regulation_of_metabolic_process GO:0019222 12133 4469 49 33 9189 48 2 false 0.003777127380010149 0.003777127380010149 0.0 immune_response-regulating_signaling_pathway GO:0002764 12133 310 49 7 3626 25 2 false 0.0038851317879253318 0.0038851317879253318 0.0 heat_shock_protein_binding GO:0031072 12133 49 49 3 6397 42 1 false 0.003931352059655171 0.003931352059655171 2.351284918255247E-124 protein_targeting_to_ER GO:0045047 12133 104 49 7 721 16 3 false 0.004006995667214791 0.004006995667214791 1.514347826459292E-128 positive_regulation_of_sodium_ion_transport GO:0010765 12133 11 49 2 166 2 3 false 0.004016064257028313 0.004016064257028313 2.123209741249517E-17 MAP_kinase_kinase_activity GO:0004708 12133 74 49 5 521 9 3 false 0.004038401510422051 0.004038401510422051 6.903948166738437E-92 positive_regulation_of_cell_communication GO:0010647 12133 820 49 11 4819 28 3 false 0.0042052367861556885 0.0042052367861556885 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 49 6 2025 18 2 false 0.0042425244219414845 0.0042425244219414845 5.184659787643375E-271 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 49 5 3020 36 2 false 0.004401057152804841 0.004401057152804841 1.1070924240418437E-179 cellular_response_to_organic_substance GO:0071310 12133 1347 49 19 1979 20 2 false 0.004577715174771851 0.004577715174771851 0.0 cytosolic_ribosome GO:0022626 12133 92 49 7 296 9 2 false 0.004733835612965257 0.004733835612965257 4.2784789004852985E-79 protein_complex_disassembly GO:0043241 12133 154 49 7 1031 16 2 false 0.005081114274991868 0.005081114274991868 4.7545827865276796E-188 positive_regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033145 12133 9 49 2 856 11 3 false 0.005150176046325063 0.005150176046325063 1.5339974177634096E-21 intracellular_protein_transport GO:0006886 12133 658 49 14 1672 20 3 false 0.005205394225928045 0.005205394225928045 0.0 positive_regulation_of_signaling GO:0023056 12133 817 49 11 4861 29 3 false 0.005223579003930176 0.005223579003930176 0.0 protein_kinase_CK2_complex GO:0005956 12133 1 49 1 9248 49 2 false 0.005298442906485864 0.005298442906485864 1.081314878885772E-4 regulation_of_immune_system_process GO:0002682 12133 794 49 10 6789 35 2 false 0.00538424677683824 0.00538424677683824 0.0 positive_regulation_of_phosphorylation GO:0042327 12133 563 49 11 1487 15 3 false 0.005544003125673564 0.005544003125673564 0.0 immune_response GO:0006955 12133 1006 49 12 5335 30 2 false 0.005725109889162444 0.005725109889162444 0.0 regulation_of_cellular_component_organization GO:0051128 12133 1152 49 14 7336 44 2 false 0.005737659056716762 0.005737659056716762 0.0 axon_guidance GO:0007411 12133 295 49 7 611 7 2 false 0.005892506099967639 0.005892506099967639 5.229199602535248E-183 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 49 5 1014 14 1 false 0.0059899467907822785 0.0059899467907822785 2.468210871514413E-134 negative_regulation_of_catalytic_activity GO:0043086 12133 588 49 9 4970 30 3 false 0.006157340800580528 0.006157340800580528 0.0 regulation_of_protein_complex_assembly GO:0043254 12133 185 49 6 1610 16 3 false 0.006326313495102297 0.006326313495102297 1.34790682725651E-248 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 49 11 3702 29 3 false 0.006465393009633987 0.006465393009633987 0.0 regulation_of_DNA_binding GO:0051101 12133 67 49 3 2162 13 2 false 0.0065134631010987 0.0065134631010987 3.7616659824415835E-129 RNA_helicase_activity GO:0003724 12133 27 49 3 140 3 1 false 0.006535144555163191 0.006535144555163191 1.8047202528374888E-29 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 49 13 1975 18 1 false 0.006563841696548464 0.006563841696548464 0.0 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 49 15 3771 38 4 false 0.006791886039624842 0.006791886039624842 0.0 taxis GO:0042330 12133 488 49 7 1496 9 2 false 0.007087293202991111 0.007087293202991111 0.0 membrane_raft GO:0045121 12133 163 49 3 2995 8 1 false 0.007236660259612596 0.007236660259612596 3.9757527534590165E-274 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 49 11 2776 23 3 false 0.007707183296461699 0.007707183296461699 0.0 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 49 6 1130 13 2 false 0.00796442749393662 0.00796442749393662 2.620015602340521E-209 cellular_response_to_progesterone_stimulus GO:0071393 12133 1 49 1 117 1 3 false 0.008547008547008409 0.008547008547008409 0.008547008547008409 nuclear_body GO:0016604 12133 272 49 7 805 9 1 false 0.00867083218507847 0.00867083218507847 8.12188174084084E-223 activation_of_immune_response GO:0002253 12133 341 49 7 1618 13 2 false 0.009176002395841518 0.009176002395841518 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 49 27 7980 46 1 false 0.00919358055577659 0.00919358055577659 0.0 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 49 15 1779 15 1 false 0.009271011026454548 0.009271011026454548 0.0 primary_metabolic_process GO:0044238 12133 7288 49 48 8027 48 1 false 0.009559401594354833 0.009559401594354833 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 49 27 7958 46 2 false 0.009590851923357322 0.009590851923357322 0.0 intracellular_part GO:0044424 12133 9083 49 49 9983 49 2 false 0.009646224429479648 0.009646224429479648 0.0 death GO:0016265 12133 1528 49 15 8052 43 1 false 0.01001614041335617 0.01001614041335617 0.0 canonical_Wnt_receptor_signaling_pathway_involved_in_positive_regulation_of_apoptotic_process GO:0044337 12133 1 49 1 488 5 2 false 0.01024590163934537 0.01024590163934537 0.002049180327868748 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 49 12 5051 30 3 false 0.010294124666082705 0.010294124666082705 0.0 SCF_complex_assembly GO:0010265 12133 1 49 1 284 3 1 false 0.010563380281691362 0.010563380281691362 0.0035211267605635955 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 49 11 1350 15 4 false 0.010596412455032733 0.010596412455032733 0.0 SH2_domain_binding GO:0042169 12133 31 49 3 486 8 1 false 0.010607309459530215 0.010607309459530215 1.1318841086292139E-49 regulation_of_catabolic_process GO:0009894 12133 554 49 10 5455 44 2 false 0.011059132786660047 0.011059132786660047 0.0 translation GO:0006412 12133 457 49 9 5433 45 3 false 0.011199901862368458 0.011199901862368458 0.0 skeletal_muscle_cell_differentiation GO:0035914 12133 57 49 3 251 3 2 false 0.01123601977631722 0.01123601977631722 6.638453930425573E-58 superior_temporal_gyrus_development GO:0071109 12133 2 49 1 3099 18 2 false 0.01158477786312434 0.01158477786312434 2.0831810007242536E-7 structural_molecule_activity GO:0005198 12133 526 49 7 10257 49 1 false 0.011842517178163979 0.011842517178163979 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 49 12 1180 19 1 false 0.011847175125109601 0.011847175125109601 0.0 signal_sequence_binding GO:0005048 12133 20 49 2 178 2 1 false 0.012061194693074855 0.012061194693074855 7.23132468780732E-27 cysteine-type_endopeptidase_activity GO:0004197 12133 219 49 5 527 5 2 false 0.012063238513205503 0.012063238513205503 1.229090165658057E-154 molecular_function GO:0003674 12133 10257 49 49 11221 49 1 false 0.012138363847867987 0.012138363847867987 0.0 platelet_activation GO:0030168 12133 203 49 4 863 5 2 false 0.012190024398312191 0.012190024398312191 1.0918730712206789E-203 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 49 7 742 7 2 false 0.012244313751091439 0.012244313751091439 9.121396596563632E-222 protein_domain_specific_binding GO:0019904 12133 486 49 8 6397 42 1 false 0.012389771748260349 0.012389771748260349 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 49 7 516 13 1 false 0.01251512231590829 0.01251512231590829 8.917305549619806E-119 small_molecule_binding GO:0036094 12133 2102 49 18 8962 46 1 false 0.012554280136152672 0.012554280136152672 0.0 chaperone-mediated_protein_folding GO:0061077 12133 21 49 2 183 2 1 false 0.012610340479191623 0.012610340479191623 5.187624892128013E-28 negative_regulation_of_cellular_process GO:0048523 12133 2515 49 20 9689 48 3 false 0.012615959256447545 0.012615959256447545 0.0 response_to_endogenous_stimulus GO:0009719 12133 982 49 11 5200 29 1 false 0.012768370050024782 0.012768370050024782 0.0 positive_regulation_of_signal_transduction GO:0009967 12133 782 49 11 3650 26 5 false 0.013055867357309327 0.013055867357309327 0.0 macromolecule_localization GO:0033036 12133 1642 49 19 3467 27 1 false 0.01307396364544779 0.01307396364544779 0.0 positive_regulation_of_catabolic_process GO:0009896 12133 137 49 5 3517 37 3 false 0.013314214256822122 0.013314214256822122 1.0965595914697655E-250 positive_regulation_of_transferase_activity GO:0051347 12133 445 49 8 2275 18 3 false 0.013917380540265926 0.013917380540265926 0.0 biosynthetic_process GO:0009058 12133 4179 49 33 8027 48 1 false 0.013950079881551693 0.013950079881551693 0.0 protein_complex_binding GO:0032403 12133 306 49 6 6397 42 1 false 0.013972919524993334 0.013972919524993334 0.0 cell_death GO:0008219 12133 1525 49 15 7542 42 2 false 0.014109497063629437 0.014109497063629437 0.0 caveola GO:0005901 12133 54 49 2 1371 5 2 false 0.014111921442824148 0.014111921442824148 2.6461252387361787E-98 replication_fork_protection_complex GO:0031298 12133 2 49 1 3062 22 3 false 0.01432040134938274 0.01432040134938274 2.133838170991397E-7 intracellular GO:0005622 12133 9171 49 49 9983 49 1 false 0.015491034119552341 0.015491034119552341 0.0 intracellular_receptor_signaling_pathway GO:0030522 12133 217 49 5 3547 25 1 false 0.0158825706302286 0.0158825706302286 0.0 regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033143 12133 43 49 3 1642 21 2 false 0.01601788538437874 0.01601788538437874 5.767987369966462E-86 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 49 21 6129 48 3 false 0.016285348783339516 0.016285348783339516 0.0 regulation_of_type_B_pancreatic_cell_development GO:2000074 12133 4 49 1 489 2 3 false 0.01630963156659913 0.01630963156659913 4.2492993816775125E-10 nucleoside_metabolic_process GO:0009116 12133 1083 49 11 2072 13 4 false 0.016666479129641462 0.016666479129641462 0.0 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 49 4 1054 12 3 false 0.016807696026418677 0.016807696026418677 5.573854633657796E-137 response_to_epidermal_growth_factor_stimulus GO:0070849 12133 18 49 2 1130 13 2 false 0.016856929629543892 0.016856929629543892 8.12901015644845E-40 cellular_protein_localization GO:0034613 12133 914 49 16 1438 18 2 false 0.01713355346635652 0.01713355346635652 0.0 protein_localization_to_nuclear_pore GO:0090204 12133 1 49 1 233 4 1 false 0.017167381974248493 0.017167381974248493 0.004291845493562596 positive_regulation_of_protein_modification_process GO:0031401 12133 708 49 12 2417 23 3 false 0.01725657943226474 0.01725657943226474 0.0 embryonic_cleavage GO:0040016 12133 5 49 1 1138 4 2 false 0.01748211320958515 0.01748211320958515 6.342949764440575E-14 late_endosome GO:0005770 12133 119 49 3 455 3 1 false 0.017556962394608917 0.017556962394608917 6.550278762678856E-113 negative_regulation_of_biological_process GO:0048519 12133 2732 49 20 10446 49 2 false 0.017632033714289008 0.017632033714289008 0.0 cellular_sodium_ion_homeostasis GO:0006883 12133 5 49 1 283 1 3 false 0.017667844522967165 0.017667844522967165 6.84978827344915E-11 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 49 8 1379 10 2 false 0.01784852627582819 0.01784852627582819 0.0 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 49 15 5183 36 2 false 0.018023005527172245 0.018023005527172245 0.0 regulation_of_apolipoprotein_binding GO:2000656 12133 1 49 1 109 2 2 false 0.018348623853211146 0.018348623853211146 0.009174311926605555 protein_kinase_activity GO:0004672 12133 1014 49 14 1347 14 3 false 0.018351608424362023 0.018351608424362023 0.0 negative_regulation_of_DNA_binding GO:0043392 12133 35 49 2 2119 13 3 false 0.01844691957185505 0.01844691957185505 5.275494739019896E-77 germ-line_stem_cell_division GO:0042078 12133 3 49 1 160 1 4 false 0.018750000000000037 0.018750000000000037 1.4927155481252484E-6 regulation_of_transmembrane_transporter_activity GO:0022898 12133 78 49 2 563 2 3 false 0.018981940924003265 0.018981940924003265 8.813007984613145E-98 cellular_response_to_cold GO:0070417 12133 2 49 1 1140 11 2 false 0.01921352987384566 0.01921352987384566 1.540286185173837E-6 signal_transduction GO:0007165 12133 3547 49 25 6702 35 4 false 0.019902945469378677 0.019902945469378677 0.0 defense_response GO:0006952 12133 1018 49 12 2540 18 1 false 0.02026365546488731 0.02026365546488731 0.0 water_homeostasis GO:0030104 12133 14 49 1 677 1 1 false 0.020679468242248013 0.020679468242248013 2.3492827505763342E-29 protein_catabolic_process GO:0030163 12133 498 49 10 3569 36 2 false 0.021774433407198507 0.021774433407198507 0.0 re-entry_into_mitotic_cell_cycle GO:0000320 12133 3 49 1 953 7 1 false 0.021897039887516727 0.021897039887516727 6.954099245402382E-9 glutamate_receptor_binding GO:0035254 12133 22 49 2 918 10 1 false 0.02197290477970257 0.02197290477970257 9.51424084577774E-45 male_germ-line_stem_cell_division GO:0048133 12133 3 49 1 270 2 2 false 0.022139611730686265 0.022139611730686265 3.082481027328714E-7 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 49 8 5027 38 3 false 0.02231353278796934 0.02231353278796934 0.0 regulation_of_ion_transmembrane_transporter_activity GO:0032412 12133 73 49 2 485 2 3 false 0.022390730169548158 0.022390730169548158 1.1784649326580688E-88 intracellular_protein_kinase_cascade GO:0007243 12133 806 49 11 1813 15 1 false 0.02257731135705885 0.02257731135705885 0.0 macromolecular_complex_disassembly GO:0032984 12133 199 49 7 1380 21 2 false 0.022652650549791063 0.022652650549791063 1.9082717261040364E-246 positive_regulation_of_RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0045899 12133 2 49 1 1043 12 4 false 0.022889089681129748 0.022889089681129748 1.8402548384908118E-6 negative_regulation_of_protein_binding GO:0032091 12133 36 49 2 6398 42 3 false 0.023018814126452736 0.023018814126452736 3.942631643108697E-96 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 49 6 599 10 2 false 0.02311054024662398 0.02311054024662398 1.7219296535416308E-148 negative_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043154 12133 63 49 3 1373 14 3 false 0.02333315144618389 0.02333315144618389 1.783777218833555E-110 regulation_of_kinase_activity GO:0043549 12133 654 49 11 1335 14 3 false 0.023507595035213345 0.023507595035213345 0.0 negative_regulation_of_protein_complex_assembly GO:0031333 12133 63 49 3 954 10 3 false 0.023591743109706485 0.023591743109706485 3.124938390294621E-100 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 49 7 220 8 2 false 0.024204480746262608 0.024204480746262608 1.3850176335002185E-65 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 49 9 174 9 1 false 0.025298559612664015 0.025298559612664015 2.5039480990851377E-47 cellular_membrane_organization GO:0016044 12133 784 49 9 7541 42 2 false 0.02607899116631241 0.02607899116631241 0.0 NF-kappaB_binding GO:0051059 12133 21 49 2 715 9 1 false 0.02613724960460843 0.02613724960460843 7.883315092172008E-41 nuclear_lumen GO:0031981 12133 2490 49 28 3186 30 2 false 0.02614941773935133 0.02614941773935133 0.0 I-kappaB/NF-kappaB_complex GO:0033256 12133 5 49 1 9248 49 2 false 0.026218573712241476 0.026218573712241476 1.775872679278938E-18 regulation_of_cell_death GO:0010941 12133 1062 49 11 6437 36 2 false 0.02624870521533523 0.02624870521533523 0.0 DNA_methylation GO:0006306 12133 37 49 2 225 2 4 false 0.026428571428569424 0.026428571428569424 2.946192449924989E-43 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 49 5 200 8 3 false 0.026962298851535817 0.026962298851535817 7.491323649368413E-49 filtration_diaphragm GO:0036056 12133 6 49 1 222 1 1 false 0.02702702702702625 0.02702702702702625 6.438789470640111E-12 activation_of_MAPK_activity GO:0000187 12133 158 49 6 286 6 2 false 0.027224135057754856 0.027224135057754856 8.207976102051858E-85 response_to_dsRNA GO:0043331 12133 36 49 2 784 6 2 false 0.027384535401845957 0.027384535401845957 5.364553057081943E-63 hippocampus_development GO:0021766 12133 46 49 2 3152 18 4 false 0.02748423279547129 0.02748423279547129 8.889994332374666E-104 organic_substance_metabolic_process GO:0071704 12133 7451 49 48 8027 48 1 false 0.027733527123119453 0.027733527123119453 0.0 tau_protein_binding GO:0048156 12133 8 49 1 556 2 1 false 0.028595501976798565 0.028595501976798565 4.643999263320968E-18 regulation_of_sodium_ion_transport GO:0002028 12133 37 49 2 215 2 2 false 0.02895022821125634 0.02895022821125634 1.8499074186131244E-42 autophagic_vacuole GO:0005776 12133 32 49 2 310 3 1 false 0.029050561089393523 0.029050561089393523 2.6078243370159197E-44 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 49 6 859 13 3 false 0.029147316681986155 0.029147316681986155 4.662302019201105E-186 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 49 12 1356 19 2 false 0.029195425181968222 0.029195425181968222 0.0 MAP_kinase_activity GO:0004707 12133 277 49 8 520 9 2 false 0.029646040412112353 0.029646040412112353 2.5282679507054518E-155 biological_process GO:0008150 12133 10446 49 49 11221 49 1 false 0.029758944413439535 0.029758944413439535 0.0 sodium_ion_transport GO:0006814 12133 95 49 2 545 2 2 false 0.030120075553164143 0.030120075553164143 6.918862196703055E-109 regulation_of_primary_metabolic_process GO:0080090 12133 3921 49 32 7507 48 2 false 0.030237996379126178 0.030237996379126178 0.0 negative_regulation_of_dendrite_morphogenesis GO:0050774 12133 5 49 1 163 1 4 false 0.03067484662576674 0.03067484662576674 1.1095213002304708E-9 cysteine-type_peptidase_activity GO:0008234 12133 295 49 5 586 5 1 false 0.03178739499494029 0.03178739499494029 1.2148857586981575E-175 immune_system_process GO:0002376 12133 1618 49 13 10446 49 1 false 0.03216573228925912 0.03216573228925912 0.0 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 49 5 7778 44 4 false 0.032225249011359834 0.032225249011359834 0.0 signaling GO:0023052 12133 3878 49 25 10446 49 1 false 0.03234144838203338 0.03234144838203338 0.0 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 49 7 3842 29 3 false 0.03245674814531744 0.03245674814531744 0.0 negative_regulation_of_glycogen_(starch)_synthase_activity GO:2000466 12133 3 49 1 183 2 3 false 0.032606737524766984 0.032606737524766984 9.952912769686522E-7 RNA_splicing GO:0008380 12133 307 49 11 601 14 1 false 0.032806442655787194 0.032806442655787194 4.262015823312228E-180 cell_part GO:0044464 12133 9983 49 49 10701 49 2 false 0.03300313561873539 0.03300313561873539 0.0 cell GO:0005623 12133 9984 49 49 10701 49 1 false 0.03316590901050192 0.03316590901050192 0.0 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 49 4 1198 20 4 false 0.03331436613543389 0.03331436613543389 2.335035261625238E-122 cellular_response_to_biotic_stimulus GO:0071216 12133 112 49 3 4357 28 2 false 0.03396793158510533 0.03396793158510533 2.1448689284216048E-225 establishment_of_protein_localization GO:0045184 12133 1153 49 15 3010 26 2 false 0.03456872675656722 0.03456872675656722 0.0 negative_regulation_of_type_B_pancreatic_cell_development GO:2000077 12133 2 49 1 115 2 3 false 0.034630053394356375 0.034630053394356375 1.5255530129672408E-4 intracellular_estrogen_receptor_signaling_pathway GO:0030520 12133 34 49 3 102 3 1 false 0.03485148514851519 0.03485148514851519 7.615480469304384E-28 protein_localization_to_organelle GO:0033365 12133 516 49 13 914 16 1 false 0.035168229191580455 0.035168229191580455 5.634955900168089E-271 regulation_of_interferon-gamma-mediated_signaling_pathway GO:0060334 12133 22 49 2 114 2 3 false 0.035863996273872246 0.035863996273872246 5.496543393824805E-24 intracellular_organelle_lumen GO:0070013 12133 2919 49 28 5320 40 2 false 0.03668102092679136 0.03668102092679136 0.0 ephrin_receptor_binding GO:0046875 12133 29 49 2 918 10 1 false 0.03707022836398003 0.03707022836398003 1.6526990639165767E-55 organelle_inheritance GO:0048308 12133 7 49 1 2031 11 1 false 0.03735620302825292 0.03735620302825292 3.5723693959710586E-20 organelle_lumen GO:0043233 12133 2968 49 28 5401 40 2 false 0.0375532174579699 0.0375532174579699 0.0 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 49 9 912 13 2 false 0.03760533622936892 0.03760533622936892 2.059888800891414E-267 regulation_of_Golgi_inheritance GO:0090170 12133 4 49 1 522 5 2 false 0.037874633565778325 0.037874633565778325 3.269883756840743E-10 transcription_factor_binding GO:0008134 12133 715 49 9 6397 42 1 false 0.03922086102518884 0.03922086102518884 0.0 morphogenesis_of_an_endothelium GO:0003159 12133 7 49 1 352 2 2 false 0.039432789432789946 0.039432789432789946 7.992864813964357E-15 retrograde_protein_transport,_ER_to_cytosol GO:0030970 12133 4 49 1 2378 24 2 false 0.039787732954454175 0.039787732954454175 7.524197028078642E-13 negative_regulation_of_apolipoprotein_binding GO:2000657 12133 1 49 1 50 2 3 false 0.03999999999999978 0.03999999999999978 0.01999999999999985 organic_substance_biosynthetic_process GO:1901576 12133 4134 49 33 7470 48 2 false 0.04041621695309538 0.04041621695309538 0.0 p53_binding GO:0002039 12133 49 49 2 6397 42 1 false 0.04074565762821446 0.04074565762821446 2.351284918255247E-124 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 49 2 201 2 3 false 0.04079601990049252 0.04079601990049252 9.949481941404742E-44 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 49 1 6481 45 2 false 0.040959269917397984 0.040959269917397984 9.738359623180132E-21 regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033146 12133 20 49 3 56 3 2 false 0.04112554112554134 0.04112554112554134 1.2728904491493287E-15 cytoplasmic_mRNA_processing_body GO:0000932 12133 44 49 2 5117 38 2 false 0.0417778620508194 0.0417778620508194 2.0344134807470182E-109 PcG_protein_complex GO:0031519 12133 40 49 2 4399 36 2 false 0.04181561475326436 0.04181561475326436 1.797728838055178E-98 receptor_tyrosine_kinase_binding GO:0030971 12133 31 49 2 918 10 1 false 0.041963592146696635 0.041963592146696635 1.9469822979582718E-58 nucleus_organization GO:0006997 12133 62 49 2 2031 11 1 false 0.04224140360646231 0.04224140360646231 6.73570952581451E-120 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 49 2 1977 17 3 false 0.04279863339056636 0.04279863339056636 8.49513097758148E-83 RNA-dependent_ATPase_activity GO:0008186 12133 21 49 2 228 4 1 false 0.043395866376402914 0.043395866376402914 4.020483440001667E-30 establishment_of_localization_in_cell GO:0051649 12133 1633 49 19 2978 26 2 false 0.04440646077573372 0.04440646077573372 0.0 negative_regulation_of_protein_dephosphorylation GO:0035308 12133 4 49 1 444 5 4 false 0.04443771160389061 0.04443771160389061 6.259846539070891E-10 cerebral_cortex_development GO:0021987 12133 60 49 2 3152 18 3 false 0.044844072865492336 0.044844072865492336 1.7800361131587683E-128 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 49 15 2780 23 2 false 0.04496625196355079 0.04496625196355079 0.0 asymmetric_cell_division GO:0008356 12133 10 49 1 438 2 1 false 0.04519189576084573 0.04519189576084573 1.5487001790918433E-20 DNA_topoisomerase_activity GO:0003916 12133 8 49 1 2199 13 2 false 0.04639951145918905 0.04639951145918905 7.468869718379493E-23 regulation_of_protein_kinase_activity GO:0045859 12133 621 49 11 1169 14 3 false 0.046674420969565325 0.046674420969565325 0.0 single-organism_process GO:0044699 12133 8052 49 43 10446 49 1 false 0.04685804446821416 0.04685804446821416 0.0 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 49 7 856 13 3 false 0.0469550364245191 0.0469550364245191 2.175375701359491E-221 protein_import_into_nucleus,_translocation GO:0000060 12133 35 49 2 2378 24 3 false 0.047441596849824914 0.047441596849824914 9.036748006294301E-79 negative_regulation_of_myeloid_cell_differentiation GO:0045638 12133 52 49 2 543 4 3 false 0.047630387456722684 0.047630387456722684 6.206039090414828E-74 cellular_response_to_stress GO:0033554 12133 1124 49 11 4743 28 2 false 0.047757535595015915 0.047757535595015915 0.0 cellular_biosynthetic_process GO:0044249 12133 4077 49 33 7290 48 2 false 0.0479579103169729 0.0479579103169729 0.0 positive_regulation_of_response_to_DNA_damage_stimulus GO:2001022 12133 44 49 2 3212 26 4 false 0.04841836581134549 0.04841836581134549 1.7987290458431554E-100 lipopolysaccharide-mediated_signaling_pathway GO:0031663 12133 40 49 2 1999 18 2 false 0.048813595088026455 0.048813595088026455 1.1212958284897253E-84 Fc-gamma_receptor_signaling_pathway_involved_in_phagocytosis GO:0038096 12133 72 49 4 151 4 4 false 0.04943354839794618 0.04943354839794618 6.349846956956757E-45 limbic_system_development GO:0021761 12133 61 49 2 2686 16 2 false 0.04963610910212993 0.04963610910212993 6.732470891549266E-126 caveolin-mediated_endocytosis GO:0072584 12133 5 49 1 2359 24 2 false 0.049885878004393674 0.049885878004393674 1.6496192818714521E-15 positive_regulation_of_stem_cell_differentiation GO:2000738 12133 10 49 1 590 3 3 false 0.050074025178540836 0.050074025178540836 7.665602552250558E-22 peptidyl-tyrosine_autophosphorylation GO:0038083 12133 4 49 1 312 4 2 false 0.05054321694771439 0.05054321694771439 2.5821180013979716E-9 macromolecule_biosynthetic_process GO:0009059 12133 3475 49 31 6537 47 2 false 0.05178428305050791 0.05178428305050791 0.0 neurotrophin_receptor_binding GO:0005165 12133 9 49 1 172 1 1 false 0.05232558139534907 0.05232558139534907 3.4075419916065225E-15 positive_regulation_of_chondrocyte_differentiation GO:0032332 12133 13 49 1 471 2 3 false 0.05449699597959148 0.05449699597959148 1.3109155517602295E-25 catalytic_activity GO:0003824 12133 4901 49 29 10478 49 2 false 0.054694631248327484 0.054694631248327484 0.0 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 49 8 750 12 3 false 0.05474848767629019 0.05474848767629019 3.090255244762607E-218 regulation_of_proteasomal_protein_catabolic_process GO:0061136 12133 67 49 3 1672 22 5 false 0.054934104391705096 0.054934104391705096 1.5388096674355026E-121 regulation_of_MAP_kinase_activity GO:0043405 12133 268 49 8 533 10 3 false 0.0550122160538741 0.0550122160538741 1.0382438249699724E-159 adiponectin-mediated_signaling_pathway GO:0033211 12133 3 49 1 318 6 1 false 0.055714736690629145 0.055714736690629145 1.8835527421137004E-7 maintenance_of_DNA_methylation GO:0010216 12133 5 49 1 791 9 2 false 0.0557479933179108 0.0557479933179108 3.9246390269706394E-13 negative_regulation_of_glycogen_biosynthetic_process GO:0045719 12133 7 49 1 860 7 4 false 0.055794361391355074 0.055794361391355074 1.4844755928807546E-17 phagocytosis GO:0006909 12133 149 49 4 2417 24 2 false 0.05617507439070483 0.05617507439070483 3.130675140672653E-242 endothelial_tube_morphogenesis GO:0061154 12133 7 49 1 245 2 2 false 0.05644028103044195 0.05644028103044195 1.0371147261725795E-13 regulation_of_cell_junction_assembly GO:1901888 12133 35 49 2 1245 14 3 false 0.056547144430008175 0.056547144430008175 7.812749785355693E-69 Ras_protein_signal_transduction GO:0007265 12133 365 49 7 547 7 1 false 0.057775251234929825 0.057775251234929825 2.1494674666292624E-150 protein_targeting_to_membrane GO:0006612 12133 145 49 7 443 12 1 false 0.05804852673245905 0.05804852673245905 5.648405296311656E-121 ribosomal_protein_import_into_nucleus GO:0006610 12133 4 49 1 200 3 1 false 0.05909852291761507 0.05909852291761507 1.545954661787468E-8 pore_complex GO:0046930 12133 84 49 2 5051 24 3 false 0.05955980298586046 0.05955980298586046 5.4712090537168384E-185 mitotic_nuclear_envelope_reassembly GO:0007084 12133 8 49 1 1043 8 3 false 0.05993522913812486 0.05993522913812486 2.957556257561267E-20 nucleic_acid_binding GO:0003676 12133 2849 49 26 4407 33 2 false 0.06003019259646862 0.06003019259646862 0.0 mRNA_splice_site_selection GO:0006376 12133 18 49 2 117 3 2 false 0.06136547111059822 0.06136547111059822 1.505085052005422E-21 regulation_of_protein_modification_process GO:0031399 12133 1001 49 14 2566 25 2 false 0.0628607101346693 0.0628607101346693 0.0 cellular_response_to_stimulus GO:0051716 12133 4236 49 28 7871 42 2 false 0.06314840789618685 0.06314840789618685 0.0 uterus_development GO:0060065 12133 11 49 1 2873 17 3 false 0.0633038424180456 0.0633038424180456 3.6964769721782132E-31 mRNA_catabolic_process GO:0006402 12133 181 49 9 592 18 2 false 0.06351864972330945 0.06351864972330945 1.4563864024176219E-157 ATPase_activity GO:0016887 12133 307 49 6 1069 11 2 false 0.06359564077751798 0.06359564077751798 1.5605649392254874E-277 regulation_of_innate_immune_response GO:0045088 12133 226 49 6 868 12 3 false 0.06368175679908629 0.06368175679908629 2.196344369914344E-215 transferase_activity GO:0016740 12133 1779 49 15 4901 29 1 false 0.06397934415322137 0.06397934415322137 0.0 negative_regulation_of_tyrosine_phosphorylation_of_STAT_protein GO:0042532 12133 5 49 1 78 1 4 false 0.0641025641025628 0.0641025641025628 4.736846842109758E-8 regulation_of_mRNA_processing GO:0050684 12133 49 49 2 3175 27 3 false 0.06412034970564182 0.06412034970564182 2.292701139367024E-109 negative_regulation_of_protein_homooligomerization GO:0032463 12133 6 49 1 184 2 3 false 0.06432644333570575 0.06432644333570575 2.0145965447507594E-11 positive_regulation_of_cartilage_development GO:0061036 12133 11 49 1 660 4 3 false 0.0651630107985405 0.0651630107985405 4.1933112070799914E-24 mRNA_3'-splice_site_recognition GO:0000389 12133 5 49 2 18 2 1 false 0.06535947712418336 0.06535947712418336 1.1671335200746984E-4 cytokine-mediated_signaling_pathway GO:0019221 12133 318 49 6 2013 19 2 false 0.06555866069667757 0.06555866069667757 0.0 channel_inhibitor_activity GO:0016248 12133 20 49 1 304 1 2 false 0.06578947368420382 0.06578947368420382 1.0141079171115058E-31 regulation_of_early_endosome_to_late_endosome_transport GO:2000641 12133 6 49 1 441 5 3 false 0.0664951769352375 0.0664951769352375 1.0128256082319477E-13 RNA_metabolic_process GO:0016070 12133 3294 49 33 5627 47 2 false 0.06726982140345343 0.06726982140345343 0.0 cytoplasmic_transport GO:0016482 12133 666 49 14 1148 18 1 false 0.0673342414135642 0.0673342414135642 0.0 beta-catenin_destruction_complex GO:0030877 12133 10 49 1 6481 45 2 false 0.06734926864789197 0.06734926864789197 2.794858090312749E-32 regulation_of_phosphorylation GO:0042325 12133 845 49 12 1820 18 2 false 0.06759803642070131 0.06759803642070131 0.0 hydrolase_activity,_acting_on_ether_bonds GO:0016801 12133 10 49 1 2556 18 1 false 0.06834885866058883 0.06834885866058883 3.1032020822227462E-28 site_of_double-strand_break GO:0035861 12133 6 49 1 512 6 1 false 0.06861043417111969 0.06861043417111969 4.116062922895253E-14 regulation_of_localization GO:0032879 12133 1242 49 11 7621 42 2 false 0.06882231043536442 0.06882231043536442 0.0 receptor_binding GO:0005102 12133 918 49 10 6397 42 1 false 0.0691364474407794 0.0691364474407794 0.0 protein_kinase_A_catalytic_subunit_binding GO:0034236 12133 5 49 1 353 5 2 false 0.06922566733602453 0.06922566733602453 2.2524921670197475E-11 histone_pre-mRNA_3'end_processing_complex GO:0071204 12133 6 49 1 3020 36 2 false 0.06948109846658677 0.06948109846658677 9.537822615543818E-19 MAP_kinase_kinase_kinase_activity GO:0004709 12133 26 49 2 520 9 3 false 0.06973152925794662 0.06973152925794662 1.8429565665115438E-44 sodium_channel_inhibitor_activity GO:0019871 12133 3 49 1 43 1 3 false 0.06976744186046464 0.06976744186046464 8.103071063933269E-5 prostaglandin-E_synthase_activity GO:0050220 12133 3 49 1 43 1 1 false 0.06976744186046464 0.06976744186046464 8.103071063933269E-5 ion_channel_inhibitor_activity GO:0008200 12133 20 49 1 286 1 2 false 0.06993006993007066 0.06993006993007066 3.5818833657211076E-31 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 49 3 1679 16 3 false 0.07006976721962369 0.07006976721962369 1.5952227787322578E-167 coagulation GO:0050817 12133 446 49 5 4095 21 1 false 0.07012888937298488 0.07012888937298488 0.0 negative_regulation_of_cysteine-type_endopeptidase_activity GO:2000117 12133 66 49 3 303 5 3 false 0.0708872979565405 0.0708872979565405 1.924144504065005E-68 microtubule_cytoskeleton GO:0015630 12133 734 49 6 1430 7 1 false 0.07120362135535001 0.07120362135535001 0.0 regulation_of_immune_response GO:0050776 12133 533 49 9 2461 25 3 false 0.07151684684081124 0.07151684684081124 0.0 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 49 18 3547 25 1 false 0.07208384769760201 0.07208384769760201 0.0 regulation_of_RNA_splicing GO:0043484 12133 52 49 2 3151 27 3 false 0.07213705016888254 0.07213705016888254 1.4828410310444421E-114 mitotic_spindle_checkpoint GO:0071174 12133 38 49 2 140 2 2 false 0.07225077081191664 0.07225077081191664 3.73538767395573E-35 negative_regulation_of_sodium_ion_transport GO:0010766 12133 5 49 1 135 2 3 false 0.07296849087893463 0.07296849087893463 2.884335739945468E-9 positive_regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032436 12133 35 49 2 288 4 4 false 0.0736521181001063 0.0736521181001063 7.428075320192054E-46 male_sex_determination GO:0030238 12133 13 49 1 3069 18 2 false 0.07375931765292737 0.07375931765292737 2.9810795844016348E-36 negative_regulation_of_glycogen_metabolic_process GO:0070874 12133 9 49 1 1299 11 4 false 0.07390153544389519 0.07390153544389519 3.5427694104400185E-23 glycosyl_compound_metabolic_process GO:1901657 12133 1093 49 11 7599 48 2 false 0.07486392717442517 0.07486392717442517 0.0 GDP-dissociation_inhibitor_activity GO:0005092 12133 12 49 1 313 2 2 false 0.07532563283360637 0.07532563283360637 6.706932837082101E-22 positive_regulation_of_ion_transport GO:0043270 12133 86 49 2 1086 6 3 false 0.07541949158783404 0.07541949158783404 6.3756507891276546E-130 GTPase_inhibitor_activity GO:0005095 12133 13 49 1 836 5 3 false 0.07554573002908307 0.07554573002908307 7.01976356108195E-29 transcriptional_repressor_complex GO:0017053 12133 60 49 2 3138 24 2 false 0.07584176846131303 0.07584176846131303 2.3309177667820233E-128 positive_regulation_of_cation_channel_activity GO:2001259 12133 17 49 1 224 1 3 false 0.07589285714285353 0.07589285714285353 7.366387194248368E-26 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 49 4 1376 14 3 false 0.07618475220011311 0.07618475220011311 2.059495184181185E-218 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 49 30 5597 43 2 false 0.07653511185291684 0.07653511185291684 0.0 gene_expression GO:0010467 12133 3708 49 34 6052 47 1 false 0.07657990153335549 0.07657990153335549 0.0 Wnt_receptor_signaling_pathway GO:0016055 12133 260 49 5 1975 18 1 false 0.07667780461484784 0.07667780461484784 0.0 single-organism_cellular_process GO:0044763 12133 7541 49 42 9888 49 2 false 0.0769950781745488 0.0769950781745488 0.0 regulation_of_protein_phosphorylation GO:0001932 12133 787 49 12 1444 16 3 false 0.07810220866043249 0.07810220866043249 0.0 SUMO_ligase_activity GO:0019789 12133 9 49 1 335 3 1 false 0.07868007430078185 0.07868007430078185 7.610794818623194E-18 small_conjugating_protein_binding GO:0032182 12133 71 49 2 6397 42 1 false 0.07871477384742831 0.07871477384742831 7.493300865579233E-169 negative_regulation_of_metabolic_process GO:0009892 12133 1354 49 12 8327 48 3 false 0.07879297740721829 0.07879297740721829 0.0 cell_projection_morphogenesis GO:0048858 12133 541 49 7 946 8 3 false 0.07907081496443207 0.07907081496443207 1.1683643564827775E-279 heterocycle_biosynthetic_process GO:0018130 12133 3248 49 30 5588 43 2 false 0.07936468454950647 0.07936468454950647 0.0 regulation_of_stem_cell_differentiation GO:2000736 12133 64 49 2 922 7 2 false 0.07942990453195918 0.07942990453195918 2.1519323444963246E-100 regulation_of_glycogen_(starch)_synthase_activity GO:2000465 12133 5 49 1 668 11 2 false 0.07989966612649872 0.07989966612649872 9.158302744166332E-13 protein_export_from_nucleus GO:0006611 12133 46 49 2 2428 25 3 false 0.0799757177193004 0.0799757177193004 1.6048237175829586E-98 telomerase_holoenzyme_complex GO:0005697 12133 7 49 1 3020 36 2 false 0.0805954582726984 0.0805954582726984 2.2151545557067955E-21 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 49 30 5686 43 2 false 0.0811228446965648 0.0811228446965648 0.0 regulation_of_bone_resorption GO:0045124 12133 21 49 1 255 1 3 false 0.08235294117646677 0.08235294117646677 3.4565530791576048E-31 cell_growth GO:0016049 12133 299 49 4 7559 42 2 false 0.08298150989672676 0.08298150989672676 0.0 protein_C-terminus_binding GO:0008022 12133 157 49 3 6397 42 1 false 0.08313063298608979 0.08313063298608979 2.34014E-319 positive_regulation_of_activin_receptor_signaling_pathway GO:0032927 12133 6 49 1 72 1 3 false 0.08333333333333329 0.08333333333333329 6.400454360574509E-9 regulation_of_response_to_interferon-gamma GO:0060330 12133 23 49 2 319 7 3 false 0.0837112111644595 0.0837112111644595 1.507111625705858E-35 GABA_receptor_binding GO:0050811 12133 8 49 1 918 10 1 false 0.0842041975700754 0.0842041975700754 8.242553036140362E-20 DNA_topoisomerase_type_II_(ATP-hydrolyzing)_activity GO:0003918 12133 6 49 1 71 1 2 false 0.08450704225352183 0.08450704225352183 6.9823138478995105E-9 lateral_plasma_membrane GO:0016328 12133 29 49 1 1329 4 1 false 0.08456045511476601 0.08456045511476601 3.147363576559954E-60 icosanoid_metabolic_process GO:0006690 12133 52 49 1 614 1 2 false 0.08469055374594564 0.08469055374594564 7.712236630953538E-77 cellular_monovalent_inorganic_cation_homeostasis GO:0030004 12133 26 49 1 306 1 2 false 0.08496732026142838 0.08496732026142838 2.8281153145438213E-38 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 49 30 5629 43 2 false 0.08549875739426857 0.08549875739426857 0.0 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 49 7 145 7 1 false 0.0858370828918143 0.0858370828918143 1.7288474062512548E-37 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 49 7 639 9 3 false 0.08602293601528965 0.08602293601528965 1.399157780258238E-191 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 49 11 2556 18 1 false 0.08639284265778832 0.08639284265778832 0.0 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 49 12 7606 48 4 false 0.08642074391242671 0.08642074391242671 0.0 positive_regulation_of_fat_cell_differentiation GO:0045600 12133 23 49 1 518 2 3 false 0.08691366138175571 0.08691366138175571 1.5782158557327159E-40 sodium_ion_homeostasis GO:0055078 12133 26 49 1 299 1 2 false 0.08695652173913307 0.08695652173913307 5.299686091705976E-38 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 49 3 1881 15 2 false 0.08711982138436808 0.08711982138436808 3.367676499542027E-210 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 49 31 6146 47 3 false 0.08725550495859719 0.08725550495859719 0.0 IkappaB_kinase_complex GO:0008385 12133 10 49 1 3063 28 2 false 0.08786735442550743 0.08786735442550743 5.066173975414688E-29 organic_substance_transport GO:0071702 12133 1580 49 18 2783 25 1 false 0.08815347959295505 0.08815347959295505 0.0 neuron_projection_development GO:0031175 12133 575 49 7 812 7 2 false 0.0883330562485839 0.0883330562485839 3.771933680434825E-212 cellular_developmental_process GO:0048869 12133 2267 49 17 7817 43 2 false 0.0897137395965463 0.0897137395965463 0.0 positive_regulation_of_histone_phosphorylation GO:0033129 12133 5 49 1 591 11 4 false 0.08995581772050211 0.08995581772050211 1.6928209745055433E-12 response_to_cytokine_stimulus GO:0034097 12133 461 49 8 1783 19 1 false 0.09040654482405514 0.09040654482405514 0.0 regulation_of_metal_ion_transport GO:0010959 12133 159 49 2 527 2 2 false 0.09062705175289136 0.09062705175289136 1.9143009234930405E-139 negative_regulation_of_lipid_storage GO:0010888 12133 13 49 1 2747 20 3 false 0.09081240091260917 0.09081240091260917 1.263188358714261E-35 DNA_topological_change GO:0006265 12133 9 49 1 194 2 1 false 0.09086053095453998 0.09086053095453998 1.1254898761359862E-15 regulation_of_nucleoside_metabolic_process GO:0009118 12133 308 49 5 3785 30 2 false 0.09161100473875647 0.09161100473875647 0.0 negative_regulation_of_hydrolase_activity GO:0051346 12133 241 49 4 2738 20 3 false 0.09250707167717276 0.09250707167717276 0.0 pallium_development GO:0021543 12133 89 49 2 3099 18 2 false 0.09269995648376753 0.09269995648376753 1.1299570779339424E-174 cell_cycle GO:0007049 12133 1295 49 11 7541 42 1 false 0.09308989306386249 0.09308989306386249 0.0 signal_complex_assembly GO:0007172 12133 8 49 1 1808 22 2 false 0.09347215710060552 0.09347215710060552 3.5864785118030747E-22 phosphoserine_binding GO:0050815 12133 4 49 1 125 3 2 false 0.09369000786781458 0.09369000786781458 1.0318453263855228E-7 glomerular_epithelial_cell_development GO:0072310 12133 8 49 1 167 2 2 false 0.09378832696053413 0.09378832696053413 7.90168466842574E-14 exon-exon_junction_complex GO:0035145 12133 12 49 1 4399 36 2 false 0.0940146943106892 0.0940146943106892 9.260000367357379E-36 apolipoprotein_binding GO:0034185 12133 15 49 1 6397 42 1 false 0.09418214065393932 0.09418214065393932 1.0814046378226056E-45 ATP_catabolic_process GO:0006200 12133 318 49 6 1012 11 4 false 0.094249954615472 0.094249954615472 1.0026310858617265E-272 anion_binding GO:0043168 12133 2280 49 16 4448 24 1 false 0.09445886538818302 0.09445886538818302 0.0 response_to_progesterone_stimulus GO:0032570 12133 26 49 1 275 1 2 false 0.09454545454546001 0.09454545454546001 5.162609167223972E-37 regulation_of_histone_phosphorylation GO:0033127 12133 7 49 1 848 12 3 false 0.09527248165508483 0.09527248165508483 1.638483563567761E-17 developmental_process GO:0032502 12133 3447 49 21 10446 49 1 false 0.09529010752129274 0.09529010752129274 0.0 translesion_synthesis GO:0019985 12133 9 49 1 273 3 2 false 0.09601728855037367 0.09601728855037367 4.922351021851153E-17 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 49 5 1525 16 1 false 0.09633817338073894 0.09633817338073894 1.2095302863090285E-289 endocytosis GO:0006897 12133 411 49 6 895 8 2 false 0.096397111474061 0.096397111474061 2.7872223899360555E-267 inclusion_body_assembly GO:0070841 12133 10 49 1 1392 14 1 false 0.09644097326323837 0.09644097326323837 1.372279009923543E-25 cellular_component GO:0005575 12133 10701 49 49 11221 49 1 false 0.0972812108553459 0.0972812108553459 0.0 protein_phosphatase_type_2A_complex GO:0000159 12133 19 49 1 9083 49 2 false 0.097763773337671 0.097763773337671 7.7076041303239345E-59 Leydig_cell_differentiation GO:0033327 12133 10 49 1 2446 25 4 false 0.09780452188952991 0.09780452188952991 4.821684083574537E-28 negative_regulation_of_macrophage_derived_foam_cell_differentiation GO:0010745 12133 10 49 1 395 4 3 false 0.0978429321396656 0.0978429321396656 4.4022037255229464E-20 negative_regulation_of_nuclear_division GO:0051784 12133 43 49 1 436 1 3 false 0.0986238532109988 0.0986238532109988 1.634686522119006E-60 regulation_of_hydrolase_activity GO:0051336 12133 821 49 10 3094 25 2 false 0.09923413869518244 0.09923413869518244 0.0 type_I_interferon_production GO:0032606 12133 71 49 2 362 3 1 false 0.09951510792101192 0.09951510792101192 2.8677775679244762E-77 protein_localization_to_lysosome GO:0061462 12133 1 49 1 10 1 1 false 0.0999999999999999 0.0999999999999999 0.0999999999999999 regulation_of_transcription_initiation_from_RNA_polymerase_II_promoter GO:0060260 12133 13 49 1 1243 10 3 false 0.10014445418648181 0.10014445418648181 3.9219319072235074E-31 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 49 11 1730 21 2 false 0.10017332992636481 0.10017332992636481 0.0 positive_regulation_of_kinase_activity GO:0033674 12133 438 49 8 1181 14 3 false 0.10114949575181045 0.10114949575181045 0.0 chromosome,_telomeric_region GO:0000781 12133 48 49 2 512 6 1 false 0.10118602804892757 0.10118602804892757 1.088424225361165E-68 replication_fork GO:0005657 12133 48 49 2 512 6 1 false 0.10118602804892757 0.10118602804892757 1.088424225361165E-68 sodium_channel_activity GO:0005272 12133 26 49 1 256 1 3 false 0.10156249999999863 0.10156249999999863 3.647595212320824E-36 stem_cell_division GO:0017145 12133 23 49 1 438 2 1 false 0.10237923576063962 0.10237923576063962 8.200849076058926E-39 DNA_modification GO:0006304 12133 62 49 2 2948 26 2 false 0.10249584363500214 0.10249584363500214 4.6529599905384535E-130 amino_acid_import GO:0043090 12133 8 49 1 78 1 1 false 0.1025641025641005 0.1025641025641005 4.2649595337023847E-11 telomeric_DNA_binding GO:0042162 12133 16 49 1 1189 8 1 false 0.10300677284277793 0.10300677284277793 1.4512187070438412E-36 renal_filtration_cell_differentiation GO:0061318 12133 14 49 1 2196 17 2 false 0.10338182839508649 0.10338182839508649 1.4982675159565203E-36 DNA_catabolic_process,_endonucleolytic GO:0000737 12133 27 49 1 257 1 2 false 0.10505836575875643 0.10505836575875643 3.832103919558655E-37 dendritic_shaft GO:0043198 12133 22 49 1 596 3 2 false 0.10687371145322404 0.10687371145322404 1.4646564527106403E-40 response_to_stress GO:0006950 12133 2540 49 18 5200 29 1 false 0.10688567599940485 0.10688567599940485 0.0 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 49 8 1112 14 4 false 0.1070965367432535 0.1070965367432535 1.302733E-318 podosome_assembly GO:0071800 12133 11 49 1 878 9 2 false 0.1077350565691229 0.1077350565691229 1.7784038056438803E-25 regulation_of_potassium_ion_transmembrane_transport GO:1901379 12133 12 49 1 216 2 3 false 0.10826873385011943 0.10826873385011943 6.338882729411382E-20 regulation_of_type_I_interferon_production GO:0032479 12133 67 49 2 325 3 2 false 0.10908117453008048 0.10908117453008048 2.788484219003069E-71 positive_regulation_of_histone_acetylation GO:0035066 12133 16 49 1 144 1 4 false 0.11111111111111084 0.11111111111111084 1.4536629180584386E-21 locomotion GO:0040011 12133 1045 49 8 10446 49 1 false 0.11153764651437424 0.11153764651437424 0.0 pre-autophagosomal_structure GO:0000407 12133 16 49 1 5117 38 1 false 0.11258170312341166 0.11258170312341166 9.695449886980499E-47 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 49 7 766 8 2 false 0.11267781872129036 0.11267781872129036 4.217322594612318E-222 positive_regulation_of_integrin_activation GO:0033625 12133 3 49 1 103 4 3 false 0.11310085891512862 0.11310085891512862 5.654477498006604E-6 positive_regulation_of_cellular_catabolic_process GO:0031331 12133 106 49 3 3311 37 4 false 0.11326006107338152 0.11326006107338152 4.802217577498734E-203 negative_regulation_of_cell_junction_assembly GO:1901889 12133 9 49 1 454 6 3 false 0.11379875406277264 0.11379875406277264 4.796392891885268E-19 cellular_process GO:0009987 12133 9675 49 48 10446 49 1 false 0.11396727855013254 0.11396727855013254 0.0 regulation_of_potassium_ion_transmembrane_transporter_activity GO:1901016 12133 9 49 1 153 2 3 false 0.11455108359131388 0.11455108359131388 1.0038611131963863E-14 protein_transport GO:0015031 12133 1099 49 15 1627 18 2 false 0.11474712713264876 0.11474712713264876 0.0 positive_regulation_of_ion_transmembrane_transporter_activity GO:0032414 12133 28 49 1 473 2 3 false 0.1150069874941671 0.1150069874941671 8.750359231366189E-46 positive_regulation_of_immune_system_process GO:0002684 12133 540 49 7 3595 28 3 false 0.11503823678397185 0.11503823678397185 0.0 regulation_of_response_to_stress GO:0080134 12133 674 49 8 3466 26 2 false 0.11505260506720198 0.11505260506720198 0.0 regulation_of_body_fluid_levels GO:0050878 12133 527 49 5 4595 23 2 false 0.11506013353314752 0.11506013353314752 0.0 negative_regulation_of_Notch_signaling_pathway GO:0045746 12133 13 49 1 646 6 3 false 0.11525349509884543 0.11525349509884543 2.0608061601230117E-27 syncytium_formation GO:0006949 12133 22 49 1 7700 43 3 false 0.11606368118032971 0.11606368118032971 3.6392477021038637E-65 germ_cell_nucleus GO:0043073 12133 15 49 1 4764 39 1 false 0.11616390786681 0.11616390786681 9.047009090366007E-44 regulation_of_DNA-dependent_transcription,_initiation GO:2000142 12133 15 49 1 2670 22 3 false 0.11700472814315482 0.11700472814315482 5.444282950561458E-40 protein_phosphorylation GO:0006468 12133 1195 49 14 2577 23 2 false 0.1170156027450407 0.1170156027450407 0.0 regulation_of_epithelial_cell_migration GO:0010632 12133 90 49 2 1654 11 3 false 0.1170317162270744 0.1170317162270744 3.756993278892793E-151 negative_regulation_of_protein_oligomerization GO:0032460 12133 7 49 1 343 6 3 false 0.11718248361514098 0.11718248361514098 9.596894376022029E-15 binding GO:0005488 12133 8962 49 46 10257 49 1 false 0.117833586420143 0.117833586420143 0.0 regulation_of_cell-matrix_adhesion GO:0001952 12133 57 49 2 165 2 2 false 0.11796008869179764 0.11796008869179764 9.897591552333977E-46 energy_derivation_by_oxidation_of_organic_compounds GO:0015980 12133 271 49 2 788 2 2 false 0.1179864421210332 0.1179864421210332 1.8657076333624725E-219 RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0051123 12133 8 49 1 196 3 2 false 0.11809869070548124 0.11809869070548124 2.1395419233362556E-14 response_to_muramyl_dipeptide GO:0032495 12133 10 49 1 322 4 1 false 0.11908584031806788 0.11908584031806788 3.4874136507196575E-19 negative_regulation_of_protein_import_into_nucleus GO:0042308 12133 46 49 2 212 3 4 false 0.1194351119684135 0.1194351119684135 1.0466208389531854E-47 response_to_stimulus GO:0050896 12133 5200 49 29 10446 49 1 false 0.11957928976004972 0.11957928976004972 0.0 cellular_component_biogenesis GO:0044085 12133 1525 49 16 3839 31 1 false 0.12084950750054671 0.12084950750054671 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 49 23 7256 48 1 false 0.12103260269989204 0.12103260269989204 0.0 negative_regulation_of_tyrosine_phosphorylation_of_Stat3_protein GO:0042518 12133 4 49 1 33 1 3 false 0.12121212121212037 0.12121212121212037 2.4437927663734027E-5 intracellular_organelle GO:0043229 12133 7958 49 46 9096 49 2 false 0.12232055885804391 0.12232055885804391 0.0 single_organism_signaling GO:0044700 12133 3878 49 25 8052 43 2 false 0.12302293079263216 0.12302293079263216 0.0 regulation_of_muscle_tissue_development GO:1901861 12133 105 49 2 1351 8 2 false 0.12315407798227912 0.12315407798227912 1.3105194568745759E-159 response_to_peptide GO:1901652 12133 322 49 4 904 6 2 false 0.12351110573140284 0.12351110573140284 7.8711156655671515E-255 Sin3-type_complex GO:0070822 12133 12 49 1 280 3 3 false 0.12356308501586176 0.12356308501586176 2.6196359374220302E-21 unfolded_protein_binding GO:0051082 12133 93 49 2 6397 42 1 false 0.12400106237862835 0.12400106237862835 2.507796527596117E-210 positive_regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033148 12133 8 49 2 35 3 3 false 0.12406417112299364 0.12406417112299364 4.248842827655879E-8 ribonucleotide_catabolic_process GO:0009261 12133 946 49 11 1294 12 3 false 0.12501737965312998 0.12501737965312998 0.0 spindle_checkpoint GO:0031577 12133 45 49 2 202 3 1 false 0.1253288015368618 0.1253288015368618 4.3818533729449334E-46 cellular_response_to_ketone GO:1901655 12133 13 49 1 590 6 2 false 0.12563559658183038 0.12563559658183038 6.776870487169301E-27 regulation_of_Wnt_receptor_signaling_pathway GO:0030111 12133 156 49 4 1668 21 2 false 0.12581748934798723 0.12581748934798723 2.89270864030114E-224 protein_kinase_B_binding GO:0043422 12133 9 49 1 341 5 1 false 0.12588179826034263 0.12588179826034263 6.4745360410051145E-18 cell_leading_edge GO:0031252 12133 252 49 3 9983 49 1 false 0.12598531831269993 0.12598531831269993 0.0 regulation_of_cellular_catabolic_process GO:0031329 12133 494 49 7 5000 43 3 false 0.12631784515107247 0.12631784515107247 0.0 phosphorylation GO:0016310 12133 1421 49 15 2776 23 1 false 0.1263821956003604 0.1263821956003604 0.0 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 49 6 309 7 2 false 0.12664328495093596 0.12664328495093596 7.558729588417702E-91 neuron_projection_morphogenesis GO:0048812 12133 475 49 7 637 7 2 false 0.12675264180306878 0.12675264180306878 3.7535814082411355E-156 DNA-dependent_transcriptional_preinitiation_complex_assembly GO:0070897 12133 9 49 1 338 5 2 false 0.12694560491829768 0.12694560491829768 7.01716404793524E-18 regulation_of_protein_binding GO:0043393 12133 95 49 2 6398 42 2 false 0.12835470618864303 0.12835470618864303 5.5524328548337306E-214 positive_regulation_of_immune_response GO:0050778 12133 394 49 7 1600 18 4 false 0.12925796054809896 0.12925796054809896 0.0 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 49 31 6638 48 2 false 0.12936691639177447 0.12936691639177447 0.0 protein_kinase_A_binding GO:0051018 12133 21 49 1 6397 42 1 false 0.12937955560737627 0.12937955560737627 6.26776595449863E-61 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 49 4 129 4 1 false 0.12956456387719764 0.12956456387719764 3.5310664374642874E-37 cell_projection_organization GO:0030030 12133 744 49 7 7663 44 2 false 0.12962613788628968 0.12962613788628968 0.0 positive_regulation_of_signal_transduction_by_p53_class_mediator GO:1901798 12133 11 49 1 881 11 3 false 0.12977567746579574 0.12977567746579574 1.712543759931694E-25 nucleolus GO:0005730 12133 1357 49 16 4208 38 3 false 0.12977929623675816 0.12977929623675816 0.0 negative_regulation_of_peptidase_activity GO:0010466 12133 156 49 3 695 6 3 false 0.13028673226713866 0.13028673226713866 5.1885244604442586E-160 negative_regulation_of_anoikis GO:2000811 12133 15 49 1 542 5 3 false 0.1313850771302687 0.1313850771302687 1.5538364959648575E-29 nucleotide_catabolic_process GO:0009166 12133 969 49 11 1318 12 2 false 0.13155814217544218 0.13155814217544218 0.0 protein_autophosphorylation GO:0046777 12133 173 49 4 1195 14 1 false 0.13169770134467923 0.13169770134467923 7.421869914925723E-214 anatomical_structure_homeostasis GO:0060249 12133 166 49 2 990 4 1 false 0.13299872798134393 0.13299872798134393 1.128853988781411E-193 molecular_transducer_activity GO:0060089 12133 1070 49 8 10257 49 1 false 0.1331556475238097 0.1331556475238097 0.0 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 49 7 1813 15 1 false 0.1334580530086087 0.1334580530086087 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 49 9 701 11 2 false 0.13368831746411813 0.13368831746411813 1.5434745144062482E-202 estrogen_receptor_binding GO:0030331 12133 23 49 2 62 2 1 false 0.13379164463247292 0.13379164463247292 1.6756493074771417E-17 positive_regulation_of_peptidyl-lysine_acetylation GO:2000758 12133 17 49 1 127 1 3 false 0.13385826771653558 0.13385826771653558 1.8751500945612253E-21 U2-type_spliceosomal_complex GO:0005684 12133 3 49 1 150 7 1 false 0.13442590241248722 0.13442590241248722 1.813894431344149E-6 apoptotic_signaling_pathway GO:0097190 12133 305 49 4 3954 26 2 false 0.13577735370754307 0.13577735370754307 0.0 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 49 10 982 11 1 false 0.13592152171183255 0.13592152171183255 2.6984349291053464E-253 negative_regulation_of_JAK-STAT_cascade GO:0046426 12133 8 49 1 223 4 3 false 0.13683284640815407 0.13683284640815407 7.485721025490751E-15 integrin_activation GO:0033622 12133 12 49 1 743 9 1 false 0.13700365160893632 0.13700365160893632 1.850332428419763E-26 icosanoid_biosynthetic_process GO:0046456 12133 31 49 1 226 1 3 false 0.13716814159292384 0.13716814159292384 7.488265257194256E-39 regulation_of_vascular_permeability GO:0043114 12133 24 49 1 2120 13 3 false 0.13794150368867325 0.13794150368867325 1.040867174042963E-56 regulation_of_muscle_organ_development GO:0048634 12133 106 49 2 1105 7 2 false 0.1392177248866916 0.1392177248866916 5.2870889259577626E-151 positive_regulation_of_organelle_assembly GO:1902117 12133 12 49 1 649 8 3 false 0.13939841058213903 0.13939841058213903 9.502313168071326E-26 one-carbon_metabolic_process GO:0006730 12133 23 49 1 7326 48 2 false 0.1405135597432371 0.1405135597432371 3.4321711361993624E-67 ER-nucleus_signaling_pathway GO:0006984 12133 94 49 2 3547 25 1 false 0.14085726805051965 0.14085726805051965 7.751301219638514E-188 binding,_bridging GO:0060090 12133 129 49 2 8962 46 1 false 0.14159320140019044 0.14159320140019044 1.7318913122999068E-292 perikaryon GO:0043204 12133 31 49 1 9983 49 2 false 0.14166734454843846 0.14166734454843846 9.08193271158762E-91 regulation_of_DNA_methylation GO:0044030 12133 8 49 1 215 4 2 false 0.14167078145612744 0.14167078145612744 1.0074916482954158E-14 ATP_metabolic_process GO:0046034 12133 381 49 6 1209 12 3 false 0.14217044476926943 0.14217044476926943 0.0 negative_regulation_of_carbohydrate_metabolic_process GO:0045912 12133 21 49 1 1791 13 3 false 0.14259820687987457 0.14259820687987457 2.782622653106736E-49 regulation_of_protein_homooligomerization GO:0032462 12133 14 49 1 189 2 2 false 0.14302600472811533 0.14302600472811533 1.9240310274561344E-21 ribonucleoprotein_granule GO:0035770 12133 75 49 2 3365 30 2 false 0.14312584592789035 0.14312584592789035 1.704323678285534E-155 regulation_of_cell_adhesion GO:0030155 12133 244 49 3 6487 35 2 false 0.14313273590545555 0.14313273590545555 0.0 SH3/SH2_adaptor_activity GO:0005070 12133 48 49 2 126 2 2 false 0.14323809523809652 0.14323809523809652 5.926155314091347E-36 tissue_migration GO:0090130 12133 131 49 2 4095 21 1 false 0.14385034415661907 0.14385034415661907 4.3202440607580954E-251 negative_regulation_of_cellular_carbohydrate_metabolic_process GO:0010677 12133 18 49 1 1395 12 4 false 0.14484132640680375 0.14484132640680375 1.7858213811209545E-41 regulation_of_cellular_process GO:0050794 12133 6304 49 35 9757 48 2 false 0.14517113175491161 0.14517113175491161 0.0 protein_refolding GO:0042026 12133 14 49 1 183 2 1 false 0.14754098360654258 0.14754098360654258 3.073045199995708E-21 chemotaxis GO:0006935 12133 488 49 7 2369 22 2 false 0.14858349207636 0.14858349207636 0.0 ubiquitin-dependent_protein_catabolic_process_via_the_multivesicular_body_sorting_pathway GO:0043162 12133 10 49 1 379 6 3 false 0.14915097071341488 0.14915097071341488 6.689174917849262E-20 cytoplasm GO:0005737 12133 6938 49 41 9083 49 1 false 0.14926803855803902 0.14926803855803902 0.0 MAPK_cascade GO:0000165 12133 502 49 9 806 11 1 false 0.15049855546620358 0.15049855546620358 3.7900857366173457E-231 genetic_imprinting GO:0071514 12133 19 49 1 5474 47 2 false 0.1513516296194323 0.1513516296194323 1.1772958308849798E-54 negative_regulation_of_signaling GO:0023057 12133 597 49 6 4884 30 3 false 0.15180688148526872 0.15180688148526872 0.0 multivesicular_body_sorting_pathway GO:0071985 12133 17 49 1 2490 24 2 false 0.15226240903322255 0.15226240903322255 6.909596477174519E-44 negative_regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001243 12133 8 49 1 150 3 3 false 0.15258479956467 0.15258479956467 1.902149109321368E-13 phospholipid_catabolic_process GO:0009395 12133 17 49 1 1245 12 3 false 0.15271898699930062 0.15271898699930062 9.568448457906033E-39 rhythmic_process GO:0048511 12133 148 49 2 10446 49 1 false 0.15277379359337295 0.15277379359337295 0.0 regulation_of_biological_process GO:0050789 12133 6622 49 35 10446 49 2 false 0.1532362741870348 0.1532362741870348 0.0 negative_regulation_of_GTPase_activity GO:0034260 12133 17 49 1 829 8 3 false 0.15335177072745204 0.15335177072745204 1.0171061691919229E-35 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 49 6 4239 34 3 false 0.15418488027935007 0.15418488027935007 0.0 tau-protein_kinase_activity GO:0050321 12133 12 49 1 1014 14 1 false 0.15443742376355818 0.15443742376355818 4.327695188737012E-28 forebrain_development GO:0030900 12133 242 49 3 3152 18 3 false 0.15547297536661217 0.15547297536661217 0.0 negative_regulation_of_cell_communication GO:0010648 12133 599 49 6 4860 30 3 false 0.15615650262237835 0.15615650262237835 0.0 ER_overload_response GO:0006983 12133 9 49 1 217 4 3 false 0.15688067544254872 0.15688067544254872 4.023776168306997E-16 positive_regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043517 12133 11 49 1 135 2 4 false 0.15688225538970965 0.15688225538970965 2.2345648964968075E-16 BMP_signaling_pathway GO:0030509 12133 83 49 2 1276 11 2 false 0.15708421576417803 0.15708421576417803 9.874891335860256E-133 protein_serine/threonine_kinase_activity GO:0004674 12133 709 49 12 1014 14 1 false 0.15748106627807168 0.15748106627807168 1.8231541307779663E-268 regulation_of_protein_dephosphorylation GO:0035304 12133 14 49 1 1152 14 3 false 0.1581561001115902 0.1581561001115902 1.3017113495112525E-32 regulation_of_glucan_biosynthetic_process GO:0010962 12133 24 49 1 2805 20 4 false 0.15839674739460147 0.15839674739460147 1.2166606274093314E-59 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 49 4 129 4 1 false 0.15887003950088324 0.15887003950088324 2.4714073881998435E-36 regulation_of_muscle_cell_differentiation GO:0051147 12133 103 49 2 987 7 2 false 0.16011840645946634 0.16011840645946634 9.48284116235963E-143 vacuolar_protein_catabolic_process GO:0007039 12133 10 49 1 409 7 1 false 0.16018779895203095 0.16018779895203095 3.095189671373722E-20 negative_regulation_of_TOR_signaling_cascade GO:0032007 12133 17 49 1 592 6 3 false 0.1610242067785278 0.1610242067785278 3.3289701463907304E-33 regulation_of_skeletal_muscle_cell_differentiation GO:2001014 12133 27 49 2 105 3 3 false 0.1616504854368822 0.1616504854368822 1.1402717682449654E-25 protein_heterotrimerization GO:0070208 12133 6 49 1 71 2 2 false 0.16297786720322102 0.16297786720322102 6.9823138478995105E-9 response_to_cold GO:0009409 12133 25 49 1 2544 18 2 false 0.1633599174894566 0.1633599174894566 1.270858440616409E-60 postreplication_repair GO:0006301 12133 16 49 1 368 4 1 false 0.16352027559599458 0.16352027559599458 2.574562678585272E-28 polyubiquitin_binding GO:0031593 12133 25 49 2 61 2 1 false 0.163934426229512 0.163934426229512 1.1367792653855182E-17 isomerase_activity GO:0016853 12133 123 49 2 4901 29 1 false 0.16396371614972824 0.16396371614972824 7.077862449152851E-249 negative_regulation_of_systemic_arterial_blood_pressure GO:0003085 12133 11 49 1 67 1 2 false 0.16417910447761364 0.16417910447761364 7.781717560880856E-13 protein_localization_to_cytoskeleton GO:0044380 12133 7 49 1 516 13 1 false 0.16445997743399365 0.16445997743399365 5.390537659454944E-16 small_conjugating_protein_ligase_binding GO:0044389 12133 147 49 4 1005 15 1 false 0.16455386770013303 0.16455386770013303 6.302468729220369E-181 mitogen-activated_protein_kinase_kinase_binding GO:0031434 12133 12 49 1 341 5 1 false 0.16489927642176463 0.16489927642176463 2.356690583847287E-22 positive_regulation_of_lipid_transport GO:0032370 12133 23 49 1 522 4 3 false 0.16537954199639465 0.16537954199639465 1.317211240339607E-40 protein_heterooligomerization GO:0051291 12133 55 49 2 288 4 1 false 0.1659672163522771 0.1659672163522771 1.7091560629948947E-60 positive_regulation_of_proteasomal_protein_catabolic_process GO:1901800 12133 36 49 2 287 6 4 false 0.16601735505406 0.16601735505406 1.2079535246838254E-46 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 49 11 6622 35 1 false 0.16612248972748087 0.16612248972748087 0.0 ribose_phosphate_metabolic_process GO:0019693 12133 1207 49 12 3007 23 3 false 0.16620820213786325 0.16620820213786325 0.0 response_to_abiotic_stimulus GO:0009628 12133 676 49 6 5200 29 1 false 0.16631833143521743 0.16631833143521743 0.0 Golgi_inheritance GO:0048313 12133 7 49 1 42 1 2 false 0.16666666666666763 0.16666666666666763 3.7066789313259776E-8 cellular_response_to_interferon-gamma GO:0071346 12133 83 49 3 392 7 2 false 0.16708134557735696 0.16708134557735696 2.629901965674187E-87 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 49 6 5830 32 3 false 0.16782670233038455 0.16782670233038455 0.0 neuron_development GO:0048666 12133 654 49 7 1313 10 2 false 0.167828462331487 0.167828462331487 0.0 progesterone_receptor_signaling_pathway GO:0050847 12133 6 49 1 102 3 1 false 0.16785090273733302 0.16785090273733302 7.426393311971009E-10 response_to_organic_substance GO:0010033 12133 1783 49 19 2369 22 1 false 0.16806419238325696 0.16806419238325696 0.0 helicase_activity GO:0004386 12133 140 49 3 1059 11 1 false 0.16839536568201594 0.16839536568201594 6.632628106941949E-179 regulation_of_response_to_DNA_damage_stimulus GO:2001020 12133 80 49 2 741 7 2 false 0.1691572760837359 0.1691572760837359 1.553661553762129E-109 nuclear_pore GO:0005643 12133 69 49 2 2781 30 3 false 0.16963850567863714 0.16963850567863714 8.971129873692015E-140 monovalent_inorganic_cation_homeostasis GO:0055067 12133 56 49 1 330 1 1 false 0.16969696969696543 0.16969696969696543 9.24814230107908E-65 negative_regulation_of_focal_adhesion_assembly GO:0051895 12133 9 49 1 53 1 4 false 0.16981132075471547 0.16981132075471547 2.2565144472039573E-10 regulation_of_cell_differentiation GO:0045595 12133 872 49 7 6612 35 3 false 0.16992110189528173 0.16992110189528173 0.0 pre-mRNA_binding GO:0036002 12133 10 49 1 763 14 1 false 0.1699772663314854 0.1699772663314854 5.757557985229243E-23 protein_serine/threonine_phosphatase_complex GO:0008287 12133 38 49 1 10006 49 2 false 0.17046676319767057 0.17046676319767057 5.4849454028851035E-108 regulation_of_macrophage_derived_foam_cell_differentiation GO:0010743 12133 23 49 1 874 7 2 false 0.17083026826074657 0.17083026826074657 7.665512649099911E-46 rRNA_metabolic_process GO:0016072 12133 107 49 2 258 2 1 false 0.1710554097668257 0.1710554097668257 1.860360860420455E-75 tissue_development GO:0009888 12133 1132 49 9 3099 18 1 false 0.17170812500518493 0.17170812500518493 0.0 skeletal_muscle_organ_development GO:0060538 12133 172 49 3 308 3 1 false 0.17280764837764112 0.17280764837764112 3.4535917571053045E-91 cellular_protein_catabolic_process GO:0044257 12133 409 49 7 3174 36 3 false 0.1728554857508277 0.1728554857508277 0.0 organophosphate_metabolic_process GO:0019637 12133 1549 49 13 7521 48 2 false 0.17321570544410692 0.17321570544410692 0.0 beta-tubulin_binding GO:0048487 12133 26 49 1 150 1 1 false 0.1733333333333376 0.1733333333333376 1.0631424532785207E-29 regulation_of_ion_transmembrane_transport GO:0034765 12133 176 49 2 662 3 3 false 0.17404737854849717 0.17404737854849717 9.171243521861199E-166 cartilage_development GO:0051216 12133 125 49 2 1969 12 3 false 0.17421981146985013 0.17421981146985013 1.740444958523362E-201 DNA-dependent_transcription,_initiation GO:0006352 12133 225 49 4 2751 27 2 false 0.1744705920929965 0.1744705920929965 0.0 sex_determination GO:0007530 12133 21 49 1 340 3 1 false 0.17456714790432024 0.17456714790432024 6.623492102010024E-34 cell-substrate_adhesion GO:0031589 12133 190 49 2 712 3 1 false 0.17524153597453326 0.17524153597453326 1.237947563614388E-178 regulation_of_cellular_response_to_stress GO:0080135 12133 270 49 3 6503 35 3 false 0.17615613514321254 0.17615613514321254 0.0 protein_binding,_bridging GO:0030674 12133 116 49 2 6397 42 2 false 0.17638175881852666 0.17638175881852666 3.1111419589573665E-251 positive_regulation_of_sterol_transport GO:0032373 12133 11 49 1 62 1 3 false 0.1774193548387111 0.1774193548387111 1.967453119166065E-12 negative_regulation_of_nucleocytoplasmic_transport GO:0046823 12133 54 49 2 343 5 3 false 0.17760961679924084 0.17760961679924084 2.3530708460848664E-64 epithelial_cell_differentiation_involved_in_kidney_development GO:0035850 12133 31 49 1 491 3 3 false 0.17804211885044532 0.17804211885044532 8.158001597817135E-50 glucosyltransferase_activity GO:0046527 12133 13 49 1 73 1 1 false 0.17808219178082282 0.17808219178082282 1.1591414198066305E-14 sex_chromosome GO:0000803 12133 19 49 1 592 6 1 false 0.1784570078387154 0.1784570078387154 3.4495009545998527E-36 positive_regulation_of_ATPase_activity GO:0032781 12133 18 49 1 837 9 3 false 0.17849042922288771 0.17849042922288771 1.8933419964451444E-37 regulation_of_polysaccharide_biosynthetic_process GO:0032885 12133 28 49 1 2871 20 4 false 0.17853515106929915 0.17853515106929915 5.206845794112743E-68 regulation_of_transporter_activity GO:0032409 12133 88 49 2 2973 26 3 false 0.1786287045105358 0.1786287045105358 1.555650039308817E-171 regulation_of_anoikis GO:2000209 12133 18 49 1 1020 11 2 false 0.17866669852343464 0.17866669852343464 5.212641819611591E-39 regulation_of_nucleotide_catabolic_process GO:0030811 12133 306 49 5 1279 13 3 false 0.17873324340035118 0.17873324340035118 9.116385096369177E-305 sodium_channel_regulator_activity GO:0017080 12133 14 49 1 78 1 2 false 0.17948717948717585 0.17948717948717585 9.768201397951623E-16 glomerular_epithelium_development GO:0072010 12133 14 49 1 78 1 2 false 0.17948717948717585 0.17948717948717585 9.768201397951623E-16 chromosomal_part GO:0044427 12133 512 49 6 5337 40 2 false 0.1801837686442478 0.1801837686442478 0.0 NIK/NF-kappaB_cascade GO:0038061 12133 24 49 1 1828 15 2 false 0.18045750669648203 0.18045750669648203 3.725046499789671E-55 cellular_response_to_epidermal_growth_factor_stimulus GO:0071364 12133 13 49 1 860 13 3 false 0.18079246523390555 0.18079246523390555 4.8459863580015324E-29 Fc_receptor_signaling_pathway GO:0038093 12133 76 49 4 188 6 1 false 0.18140289115333014 0.18140289115333014 1.381050418692459E-54 branching_involved_in_mammary_gland_duct_morphogenesis GO:0060444 12133 26 49 1 143 1 2 false 0.18181818181817405 0.18181818181817405 4.1538343756792934E-29 kinesin_complex GO:0005871 12133 20 49 1 110 1 1 false 0.18181818181817921 0.18181818181817921 2.27584542759169E-22 excretion GO:0007588 12133 50 49 1 1272 5 1 false 0.1819488943063702 0.1819488943063702 4.8139348402185623E-91 cytoplasmic_sequestering_of_NF-kappaB GO:0007253 12133 9 49 1 49 1 3 false 0.18367346938775714 0.18367346938775714 4.867469433024523E-10 negative_regulation_of_mitosis GO:0045839 12133 43 49 1 656 3 5 false 0.18430045658035457 0.18430045658035457 1.8426541499010044E-68 response_to_interferon-gamma GO:0034341 12133 97 49 3 900 14 2 false 0.18455547741642087 0.18455547741642087 5.665951698458868E-133 TBP-class_protein_binding GO:0017025 12133 16 49 1 715 9 1 false 0.18522886577778708 0.18522886577778708 5.310604856356121E-33 sensory_perception_of_pain GO:0019233 12133 56 49 1 302 1 1 false 0.18543046357613807 0.18543046357613807 2.1666594800628652E-62 negative_regulation_of_phosphorus_metabolic_process GO:0010563 12133 278 49 4 3568 29 3 false 0.18551127603648898 0.18551127603648898 0.0 nuclear_body_organization GO:0030575 12133 6 49 1 62 2 1 false 0.1856160761501895 0.1856160761501895 1.626690238926508E-8 histone_phosphorylation GO:0016572 12133 21 49 1 1447 14 2 false 0.18584110924263836 0.18584110924263836 2.522509168644094E-47 regulation_of_steroid_metabolic_process GO:0019218 12133 56 49 1 301 1 2 false 0.18604651162788827 0.18604651162788827 2.659882776337694E-62 nucleoside_phosphate_binding GO:1901265 12133 1998 49 18 4407 33 2 false 0.1862645711544632 0.1862645711544632 0.0 anoikis GO:0043276 12133 20 49 1 1373 14 1 false 0.18650795142700827 0.18650795142700827 4.932867438631412E-45 regulation_of_histone_acetylation GO:0035065 12133 31 49 1 166 1 3 false 0.18674698795181827 0.18674698795181827 2.4571391045681945E-34 membrane_organization GO:0061024 12133 787 49 9 3745 31 1 false 0.18681502609066564 0.18681502609066564 0.0 phosphatidylinositol_phospholipase_C_activity GO:0004435 12133 20 49 1 107 1 1 false 0.18691588785047175 0.18691588785047175 4.180907049564432E-22 foam_cell_differentiation GO:0090077 12133 26 49 1 2154 17 1 false 0.18716206976555308 0.18716206976555308 1.0162913510282805E-60 cell_development GO:0048468 12133 1255 49 10 3306 20 4 false 0.18799877770974233 0.18799877770974233 0.0 hydrolase_activity GO:0016787 12133 2556 49 18 4901 29 1 false 0.18821108415056712 0.18821108415056712 0.0 nuclear_localization_sequence_binding GO:0008139 12133 9 49 2 20 2 1 false 0.18947368421052663 0.18947368421052663 5.9537985234579775E-6 negative_regulation_of_endopeptidase_activity GO:0010951 12133 152 49 3 474 5 3 false 0.1904012299304646 0.1904012299304646 1.8080345918982332E-128 autophagic_vacuole_membrane GO:0000421 12133 15 49 1 149 2 2 false 0.19181933611462923 0.19181933611462923 6.842145126024584E-21 negative_regulation_of_phosphate_metabolic_process GO:0045936 12133 278 49 4 2776 23 3 false 0.19272814850450803 0.19272814850450803 0.0 regulation_of_podosome_assembly GO:0071801 12133 7 49 1 202 6 3 false 0.19291378091036163 0.19291378091036163 4.0795527185171627E-13 positive_regulation_of_peptidyl-threonine_phosphorylation GO:0010800 12133 11 49 1 575 11 3 false 0.1929442197797975 0.1929442197797975 1.9346652287511912E-23 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 49 3 1384 11 2 false 0.19345671328160108 0.19345671328160108 1.3395090025049634E-243 regulation_of_DNA_metabolic_process GO:0051052 12133 188 49 3 4316 35 3 false 0.19403691990035066 0.19403691990035066 0.0 autophagy GO:0006914 12133 112 49 3 1972 27 1 false 0.19505887608187145 0.19505887608187145 4.585569427927113E-186 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 49 11 1319 12 1 false 0.19512003030903652 0.19512003030903652 6.536050345296563E-309 regulation_of_RNA_stability GO:0043487 12133 37 49 1 2240 13 2 false 0.19516051060982828 0.19516051060982828 2.0388833014238124E-81 negative_regulation_of_signal_transduction GO:0009968 12133 571 49 6 3588 25 5 false 0.1961096106174971 0.1961096106174971 0.0 telencephalon_development GO:0021537 12133 141 49 2 3099 18 2 false 0.19617974785151582 0.19617974785151582 2.6342742970069075E-248 positive_regulation_of_protein_export_from_nucleus GO:0046827 12133 13 49 1 126 2 4 false 0.1964444444444454 0.1964444444444454 5.8569430780046546E-18 NLS-bearing_substrate_import_into_nucleus GO:0006607 12133 14 49 1 200 3 1 false 0.19655855032738428 0.19655855032738428 8.476072934217597E-22 negative_regulation_of_transcription_factor_import_into_nucleus GO:0042992 12133 34 49 2 76 2 3 false 0.19684210526315704 0.19684210526315704 2.199973770519916E-22 skeletal_muscle_tissue_development GO:0007519 12133 168 49 3 288 3 2 false 0.19701233725620948 0.19701233725620948 2.348024843062379E-84 circadian_rhythm GO:0007623 12133 66 49 2 148 2 1 false 0.19718698290124848 0.19718698290124848 1.0122432742541851E-43 cellular_component_assembly GO:0022607 12133 1392 49 14 3836 31 2 false 0.1980402312174529 0.1980402312174529 0.0 cell_projection GO:0042995 12133 976 49 7 9983 49 1 false 0.1984110387474711 0.1984110387474711 0.0 embryonic_pattern_specification GO:0009880 12133 45 49 1 835 4 2 false 0.19908912527636058 0.19908912527636058 1.3373079124249935E-75 regulation_of_blood_vessel_endothelial_cell_migration GO:0043535 12133 36 49 2 80 2 2 false 0.19936708860759275 0.19936708860759275 1.3816777818746476E-23 regulation_of_gene_expression_by_genetic_imprinting GO:0006349 12133 13 49 1 124 2 2 false 0.19944925255703438 0.19944925255703438 7.288784250835707E-18 negative_regulation_of_cell_morphogenesis_involved_in_differentiation GO:0010771 12133 20 49 1 822 9 4 false 0.19971385013280443 0.19971385013280443 1.5483743712673206E-40 positive_regulation_of_ossification GO:0045778 12133 33 49 1 608 4 3 false 0.20051537040467823 0.20051537040467823 2.8439610059167103E-55 ruffle GO:0001726 12133 119 49 2 990 7 2 false 0.20138445890527895 0.20138445890527895 2.995179002772035E-157 regulation_of_NIK/NF-kappaB_cascade GO:1901222 12133 17 49 1 1605 21 2 false 0.20150699251560744 0.20150699251560744 1.2442844653745033E-40 negative_regulation_of_NFAT_protein_import_into_nucleus GO:0051534 12133 4 49 1 38 2 3 false 0.20199146514936064 0.20199146514936064 1.3547381968434722E-5 purine_nucleoside_catabolic_process GO:0006152 12133 939 49 11 1085 11 3 false 0.20237060282297917 0.20237060282297917 2.1746006434797338E-185 regulation_of_response_to_cytokine_stimulus GO:0060759 12133 76 49 2 2275 25 2 false 0.20242748187771084 0.20242748187771084 4.9547358949088833E-144 regulation_of_integrin_activation GO:0033623 12133 7 49 1 190 6 2 false 0.20412097830943976 0.20412097830943976 6.305407803350028E-13 cellular_response_to_lipopolysaccharide GO:0071222 12133 96 49 2 676 6 4 false 0.20440729343334074 0.20440729343334074 2.5099220445840513E-119 Golgi_organization GO:0007030 12133 42 49 1 2031 11 1 false 0.20581030835980385 0.20581030835980385 2.565892519857175E-88 negative_regulation_of_intracellular_protein_kinase_cascade GO:0010741 12133 140 49 3 1142 13 3 false 0.20664969783928344 0.20664969783928344 8.254846485029262E-184 DNA_metabolic_process GO:0006259 12133 791 49 9 5627 47 2 false 0.20697331210945719 0.20697331210945719 0.0 signaling_adaptor_activity GO:0035591 12133 65 49 2 839 11 2 false 0.20707530227650114 0.20707530227650114 9.48818477040309E-99 regulation_of_NFAT_protein_import_into_nucleus GO:0051532 12133 7 49 1 64 2 2 false 0.20833333333333054 0.20833333333333054 1.6097455489376898E-9 columnar/cuboidal_epithelial_cell_development GO:0002066 12133 22 49 1 200 2 2 false 0.2083919597989768 0.2083919597989768 8.8863587295584E-30 hippo_signaling_cascade GO:0035329 12133 28 49 1 1813 15 1 false 0.2089397392488102 0.2089397392488102 2.187819615524224E-62 identical_protein_binding GO:0042802 12133 743 49 7 6397 42 1 false 0.20929810304245203 0.20929810304245203 0.0 negative_regulation_of_RNA_splicing GO:0033119 12133 15 49 1 1037 16 3 false 0.20930474711118602 0.20930474711118602 8.39457188486895E-34 regulation_of_cell-substrate_adhesion GO:0010810 12133 96 49 2 325 3 2 false 0.20941846824198113 0.20941846824198113 4.496729814644984E-85 positive_regulation_of_mitochondrion_organization GO:0010822 12133 43 49 1 385 2 3 false 0.21116071428570166 0.21116071428570166 4.6200993055738E-58 positive_regulation_of_Wnt_receptor_signaling_pathway GO:0030177 12133 62 49 2 935 13 3 false 0.21119500885050313 0.21119500885050313 1.606337900726139E-98 mesenchymal_cell_differentiation GO:0048762 12133 118 49 2 256 2 2 false 0.2114889705882156 0.2114889705882156 3.77778946596228E-76 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 49 1 591 3 3 false 0.21180575894027992 0.21180575894027992 1.267222544612779E-68 sodium_ion_transmembrane_transporter_activity GO:0015081 12133 67 49 1 316 1 3 false 0.21202531645569045 0.21202531645569045 2.2934303131006308E-70 ribonucleoprotein_complex_assembly GO:0022618 12133 117 49 3 646 9 3 false 0.21215856798233096 0.21215856798233096 4.631331466925404E-132 regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900739 12133 24 49 1 315 3 3 false 0.21222119828171007 0.21222119828171007 1.6734366655590734E-36 regulation_of_peptidyl-serine_phosphorylation GO:0033135 12133 59 49 2 818 12 2 false 0.2122820059761322 0.2122820059761322 1.6613120232447818E-91 regulation_of_cytokine-mediated_signaling_pathway GO:0001959 12133 70 49 2 1785 22 3 false 0.21244021405713825 0.21244021405713825 1.145730192869727E-127 phosphatase_binding GO:0019902 12133 108 49 3 1005 15 1 false 0.2124924758922008 0.2124924758922008 3.014042549641288E-148 negative_regulation_of_cell_development GO:0010721 12133 106 49 2 1346 11 3 false 0.2125929453551811 0.2125929453551811 1.6785551446261856E-160 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 49 7 1546 12 3 false 0.21309833664070582 0.21309833664070582 0.0 ATP-dependent_helicase_activity GO:0008026 12133 98 49 3 228 4 2 false 0.21325169772118874 0.21325169772118874 4.1384935546953996E-67 integrin_binding GO:0005178 12133 72 49 2 1079 13 2 false 0.21331530874850824 0.21331530874850824 2.8956297077388104E-114 positive_regulation_of_peptidyl-serine_phosphorylation GO:0033138 12133 47 49 2 594 11 3 false 0.21371901167423285 0.21371901167423285 7.186758669481106E-71 regulation_of_chondrocyte_differentiation GO:0032330 12133 30 49 1 891 7 3 false 0.21382413739057538 0.21382413739057538 1.3859187672620155E-56 response_to_external_stimulus GO:0009605 12133 1046 49 8 5200 29 1 false 0.21388736030848238 0.21388736030848238 0.0 regulation_of_striated_muscle_cell_differentiation GO:0051153 12133 68 49 2 227 3 2 false 0.21432198874639413 0.21432198874639413 1.1311225924750782E-59 positive_regulation_of_podosome_assembly GO:0071803 12133 6 49 1 104 4 4 false 0.21440169321152702 0.21440169321152702 6.590300114226586E-10 Fc_receptor_mediated_stimulatory_signaling_pathway GO:0002431 12133 76 49 4 178 6 1 false 0.2147305912600335 0.2147305912600335 2.9073989409378337E-52 endocrine_pancreas_development GO:0031018 12133 42 49 1 3152 18 4 false 0.21503646133673726 0.21503646133673726 2.1194022010597017E-96 embryonic_appendage_morphogenesis GO:0035113 12133 90 49 1 417 1 2 false 0.21582733812948507 0.21582733812948507 7.345969028832012E-94 mesenchyme_development GO:0060485 12133 139 49 2 2065 13 2 false 0.21639029684869 0.21639029684869 1.8744304993238498E-220 positive_regulation_of_protein_binding GO:0032092 12133 37 49 1 6397 42 3 false 0.21683984312423446 0.21683984312423446 2.3062856812384995E-98 calcium-dependent_protein_binding GO:0048306 12133 37 49 1 6397 42 1 false 0.21683984312423446 0.21683984312423446 2.3062856812384995E-98 cell_part_morphogenesis GO:0032990 12133 551 49 7 810 8 1 false 0.21690044851216014 0.21690044851216014 1.1709501739830369E-219 transcription_from_RNA_polymerase_I_promoter GO:0006360 12133 32 49 1 2643 20 1 false 0.2169136832652585 0.2169136832652585 9.883035668106784E-75 Hsp90_protein_binding GO:0051879 12133 15 49 2 49 3 1 false 0.21846504559270524 0.21846504559270524 6.346866259278141E-13 negative_regulation_of_extrinsic_apoptotic_signaling_pathway GO:2001237 12133 18 49 1 82 1 3 false 0.21951219512194528 0.21951219512194528 1.7089577417430564E-18 fatty_acid_derivative_biosynthetic_process GO:1901570 12133 31 49 1 4152 33 2 false 0.21985332943799973 0.21985332943799973 6.277722100859956E-79 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 49 6 3605 35 4 false 0.21990819516236876 0.21990819516236876 0.0 positive_regulation_of_cholesterol_transport GO:0032376 12133 11 49 1 50 1 3 false 0.219999999999998 0.219999999999998 2.677108188163444E-11 kinase_activity GO:0016301 12133 1174 49 14 1546 16 2 false 0.22012108960224608 0.22012108960224608 0.0 coated_pit GO:0005905 12133 52 49 1 10213 49 3 false 0.22175539699571045 0.22175539699571045 3.070128605674566E-141 regulation_of_skeletal_muscle_tissue_development GO:0048641 12133 63 49 2 206 3 2 false 0.2221657310804987 0.2221657310804987 1.364605297408496E-54 mesonephros_development GO:0001823 12133 19 49 1 161 2 1 false 0.2227484472049593 0.2227484472049593 4.319464909537082E-25 positive_regulation_of_protein_acetylation GO:1901985 12133 17 49 1 823 12 3 false 0.2228928504535845 0.2228928504535845 1.1521858928998402E-35 RNA_biosynthetic_process GO:0032774 12133 2751 49 27 4191 37 3 false 0.2232430596207296 0.2232430596207296 0.0 negative_regulation_of_cell_growth GO:0030308 12133 117 49 2 2621 20 4 false 0.22368414890780414 0.22368414890780414 6.020174158767381E-207 ERBB_signaling_pathway GO:0038127 12133 199 49 5 586 10 1 false 0.2244083856976727 0.2244083856976727 2.435227003721618E-162 regulation_of_dephosphorylation GO:0035303 12133 87 49 2 1455 15 2 false 0.22475442292519865 0.22475442292519865 1.9687002630039133E-142 purine_nucleotide_catabolic_process GO:0006195 12133 956 49 11 1223 12 3 false 0.2250588108256251 0.2250588108256251 6.80299167777575E-278 multi-organism_transport GO:0044766 12133 29 49 1 3441 30 2 false 0.22507233614711694 0.22507233614711694 2.716860412473803E-72 regulation_of_purine_nucleotide_catabolic_process GO:0033121 12133 305 49 5 1088 12 3 false 0.22520595111861952 0.22520595111861952 1.7563474810306042E-279 negative_regulation_of_cell-matrix_adhesion GO:0001953 12133 17 49 1 142 2 3 false 0.22585156328038622 0.22585156328038622 2.484430929274803E-22 cell_communication GO:0007154 12133 3962 49 25 7541 42 1 false 0.22596199392405666 0.22596199392405666 0.0 MCM_complex GO:0042555 12133 36 49 1 2976 21 2 false 0.22620578781209963 0.22620578781209963 4.093123828825495E-84 MCM_core_complex GO:0097373 12133 36 49 1 2976 21 1 false 0.22620578781209963 0.22620578781209963 4.093123828825495E-84 regulation_of_gene_expression,_epigenetic GO:0040029 12133 120 49 2 2935 22 1 false 0.22629522460033097 0.22629522460033097 6.075348180017095E-217 interleukin-1-mediated_signaling_pathway GO:0070498 12133 14 49 1 336 6 2 false 0.2268796845767979 0.2268796845767979 4.907807975720428E-25 protein_localization_to_vacuole GO:0072665 12133 10 49 1 516 13 1 false 0.2269784023914801 0.2269784023914801 2.96056858819798E-21 protein_K48-linked_ubiquitination GO:0070936 12133 37 49 1 163 1 1 false 0.22699386503067412 0.22699386503067412 1.6289154422281443E-37 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 49 1 22 1 1 false 0.22727272727272646 0.22727272727272646 3.79737221842484E-5 gamete_generation GO:0007276 12133 355 49 3 581 3 3 false 0.2273650102079603 0.2273650102079603 6.960007714092178E-168 mRNA_binding GO:0003729 12133 91 49 3 763 14 1 false 0.2275425478554972 0.2275425478554972 1.7788235024198917E-120 regulation_of_tissue_remodeling GO:0034103 12133 36 49 1 1553 11 2 false 0.22805083338926385 0.22805083338926385 7.34343779200805E-74 regulation_of_polysaccharide_metabolic_process GO:0032881 12133 31 49 1 3739 31 3 false 0.22828304694595347 0.22828304694595347 1.6359150924506924E-77 regulation_of_lipid_storage GO:0010883 12133 29 49 1 1250 11 2 false 0.2283760220112797 0.2283760220112797 1.8979804083255723E-59 regulation_of_GTP_catabolic_process GO:0033124 12133 279 49 4 642 6 3 false 0.2293472605490745 0.2293472605490745 4.2701237450964594E-190 pigment_granule GO:0048770 12133 87 49 1 712 2 1 false 0.2296022377093135 0.2296022377093135 3.4546414966613156E-114 cellular_component_morphogenesis GO:0032989 12133 810 49 8 5068 37 4 false 0.22983371847607312 0.22983371847607312 0.0 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 49 1 953 7 4 false 0.23107869174991114 0.23107869174991114 1.0482452124052062E-64 signalosome GO:0008180 12133 32 49 1 4399 36 2 false 0.23194195871151907 0.23194195871151907 7.6195658646057E-82 regulation_of_biological_quality GO:0065008 12133 2082 49 13 6908 35 1 false 0.2321356772522985 0.2321356772522985 0.0 wound_healing GO:0042060 12133 543 49 5 905 6 1 false 0.23241791409641124 0.23241791409641124 1.120707554751266E-263 protein_phosphorylated_amino_acid_binding GO:0045309 12133 19 49 3 42 4 1 false 0.23374430447601613 0.23374430447601613 2.238261550776809E-12 programmed_cell_death GO:0012501 12133 1385 49 15 1525 15 1 false 0.23423730159401812 0.23423730159401812 2.142172117700311E-202 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 49 3 541 4 2 false 0.2346513220949496 0.2346513220949496 1.01164377942614E-160 negative_regulation_of_epithelial_cell_migration GO:0010633 12133 26 49 1 208 2 3 false 0.23490338164250477 0.23490338164250477 1.1069382135780033E-33 peptide_secretion GO:0002790 12133 157 49 1 668 1 2 false 0.23502994011976006 0.23502994011976006 1.7691212755864333E-157 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 49 6 417 9 4 false 0.23519724727517358 0.23519724727517358 8.022991700655629E-125 cellular_response_to_calcium_ion GO:0071277 12133 28 49 1 119 1 2 false 0.2352941176470624 0.2352941176470624 7.394441943199249E-28 negative_regulation_of_cell-substrate_adhesion GO:0010812 12133 29 49 1 231 2 3 false 0.2357989836250306 0.2357989836250306 1.5797205063531615E-37 NFAT_protein_import_into_nucleus GO:0051531 12133 8 49 1 64 2 1 false 0.23611111111110805 0.23611111111110805 2.2592919985090366E-10 macromolecule_modification GO:0043412 12133 2461 49 22 6052 47 1 false 0.23706072109816057 0.23706072109816057 0.0 chaperone_binding GO:0051087 12133 41 49 1 6397 42 1 false 0.23732785715357738 0.23732785715357738 3.429149968401103E-107 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 49 1 3208 21 2 false 0.23736252044216533 0.23736252044216533 7.591030632914061E-95 lipid_storage GO:0019915 12133 43 49 1 181 1 1 false 0.23756906077349124 0.23756906077349124 1.1493804978494703E-42 regulation_of_viral_genome_replication GO:0045069 12133 43 49 1 181 1 3 false 0.23756906077349124 0.23756906077349124 1.1493804978494703E-42 positive_regulation_of_proteolysis GO:0045862 12133 69 49 2 1334 18 3 false 0.23780218438934808 0.23780218438934808 2.369917275782091E-117 protein_serine/threonine_phosphatase_activity GO:0004722 12133 49 49 1 206 1 1 false 0.23786407766990927 0.23786407766990927 1.2741001335034851E-48 regulation_of_epithelial_to_mesenchymal_transition GO:0010717 12133 37 49 1 975 7 4 false 0.23789133021221592 0.23789133021221592 7.014478245035562E-68 origin_recognition_complex GO:0000808 12133 37 49 1 3160 23 2 false 0.23802836169967873 0.23802836169967873 5.523329685243896E-87 epithelial_to_mesenchymal_transition GO:0001837 12133 71 49 2 607 8 2 false 0.23812708573475508 0.23812708573475508 1.494030072752519E-94 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 49 4 835 11 2 false 0.23827610475225508 0.23827610475225508 8.0742416973675315E-196 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 49 11 1202 12 3 false 0.2384226328608195 0.2384226328608195 1.616697592155103E-269 mitogen-activated_protein_kinase_kinase_kinase_binding GO:0031435 12133 18 49 1 341 5 1 false 0.23875493111474586 0.23875493111474586 2.6004179619646645E-30 regulation_of_glycogen_metabolic_process GO:0070873 12133 27 49 1 113 1 4 false 0.23893805309735103 0.23893805309735103 1.1823527077796375E-26 negative_regulation_of_blood_pressure GO:0045776 12133 28 49 1 117 1 1 false 0.2393162393162351 0.2393162393162351 1.267799191286988E-27 amide_binding GO:0033218 12133 182 49 2 8962 46 1 false 0.23969435415597903 0.23969435415597903 0.0 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 49 7 1398 19 2 false 0.24029959602917128 0.24029959602917128 0.0 transcription_factor_import_into_nucleus GO:0042991 12133 64 49 2 200 3 1 false 0.2404751027866492 0.2404751027866492 5.887023324562289E-54 regulation_of_defense_response GO:0031347 12133 387 49 6 1253 14 2 false 0.24130471596812514 0.24130471596812514 0.0 glomerulus_development GO:0032835 12133 48 49 1 3152 18 3 false 0.2419255610434163 0.2419255610434163 2.079589057162791E-107 SNARE_binding GO:0000149 12133 42 49 1 6397 42 1 false 0.24236754091646623 0.24236754091646623 2.265958128878875E-109 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 49 7 374 10 2 false 0.24238419835201847 0.24238419835201847 2.0954491420584897E-111 positive_regulation_of_defense_response GO:0031349 12133 229 49 4 1621 18 3 false 0.24257920834697239 0.24257920834697239 6.85443065618377E-286 forelimb_morphogenesis GO:0035136 12133 26 49 1 107 1 1 false 0.24299065420561375 0.24299065420561375 1.906149949385078E-25 positive_regulation_of_transporter_activity GO:0032411 12133 34 49 1 2101 17 4 false 0.24302709045201476 0.24302709045201476 4.2098203958278254E-75 non-membrane_spanning_protein_tyrosine_kinase_activity GO:0004715 12133 44 49 1 180 1 1 false 0.24444444444443322 0.24444444444443322 4.841672635603901E-43 regulation_of_ossification GO:0030278 12133 137 49 2 1586 11 2 false 0.2446319601712308 0.2446319601712308 7.69235263015688E-202 negative_regulation_of_proteasomal_protein_catabolic_process GO:1901799 12133 18 49 1 267 4 4 false 0.24483754532510918 0.24483754532510918 2.4189460284559847E-28 regulation_of_multicellular_organismal_development GO:2000026 12133 953 49 7 3481 19 3 false 0.2450097739835398 0.2450097739835398 0.0 viral_genome_expression GO:0019080 12133 153 49 7 557 19 2 false 0.24530859155720663 0.24530859155720663 1.6461772406083414E-141 intracellular_signal_transduction GO:0035556 12133 1813 49 15 3547 25 1 false 0.24536939615261283 0.24536939615261283 0.0 regulation_of_mitochondrial_membrane_permeability GO:0046902 12133 46 49 1 2152 13 3 false 0.24549152511137035 0.24549152511137035 4.367031159968052E-96 kidney_development GO:0001822 12133 161 49 2 2877 17 3 false 0.24559918141258788 0.24559918141258788 9.385342690705625E-269 calmodulin_binding GO:0005516 12133 145 49 2 6397 42 1 false 0.2462848899441832 0.2462848899441832 5.666124490309724E-300 negative_regulation_of_apoptotic_signaling_pathway GO:2001234 12133 25 49 1 812 9 3 false 0.246380171217796 0.246380171217796 4.1099554708767054E-48 monovalent_inorganic_cation_transport GO:0015672 12133 302 49 2 606 2 1 false 0.24793933938863108 0.24793933938863108 1.1660817479890875E-181 ribonucleoside_catabolic_process GO:0042454 12133 946 49 11 1073 11 2 false 0.24842542640212134 0.24842542640212134 9.25790942536024E-169 nucleoplasm GO:0005654 12133 1443 49 18 2767 30 2 false 0.2485242175169668 0.2485242175169668 0.0 regulation_of_activin_receptor_signaling_pathway GO:0032925 12133 19 49 1 143 2 2 false 0.2488919531172814 0.2488919531172814 4.753428687059348E-24 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 49 6 3910 35 3 false 0.2508501718026112 0.2508501718026112 0.0 regulation_of_peptidyl-threonine_phosphorylation GO:0010799 12133 19 49 1 804 12 2 false 0.25098246414293673 0.25098246414293673 9.512945795390505E-39 regulation_of_potassium_ion_transport GO:0043266 12133 32 49 1 238 2 2 false 0.2513207814771204 0.2513207814771204 2.0777607490676014E-40 ATP_binding GO:0005524 12133 1212 49 12 1638 14 3 false 0.25193024180673945 0.25193024180673945 0.0 mammary_gland_duct_morphogenesis GO:0060603 12133 37 49 1 274 2 3 false 0.25226598219293833 0.25226598219293833 1.1164930078248282E-46 regulation_of_transmembrane_transport GO:0034762 12133 183 49 2 6614 35 3 false 0.2523696140251386 0.2523696140251386 0.0 damaged_DNA_binding GO:0003684 12133 50 49 1 2091 12 1 false 0.2526387172721169 0.2526387172721169 5.270282333276611E-102 regulation_of_cation_channel_activity GO:2001257 12133 33 49 1 244 2 2 false 0.25268164339197396 0.25268164339197396 1.3783310605710322E-41 nucleotide-binding_oligomerization_domain_containing_1_signaling_pathway GO:0070427 12133 4 49 1 30 2 1 false 0.2528735632183905 0.2528735632183905 3.648969166210552E-5 fat_cell_differentiation GO:0045444 12133 123 49 2 2154 17 1 false 0.2529214082466297 0.2529214082466297 4.3402768719462724E-204 response_to_osmotic_stress GO:0006970 12133 43 49 1 2681 18 2 false 0.25321116362909024 0.25321116362909024 3.246680302266631E-95 protein_insertion_into_mitochondrial_membrane GO:0051204 12133 25 49 1 1644 19 4 false 0.25380417888686474 0.25380417888686474 7.460154269678152E-56 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 49 3 2943 21 3 false 0.25402822494109367 0.25402822494109367 0.0 regulation_of_endopeptidase_activity GO:0052548 12133 264 49 4 480 5 2 false 0.25496249079344685 0.25496249079344685 9.691263405564588E-143 sterol_transport GO:0015918 12133 50 49 1 196 1 2 false 0.25510204081633736 0.25510204081633736 7.03456997808392E-48 regulation_of_anion_transport GO:0044070 12133 46 49 1 492 3 2 false 0.2555506331487174 0.2555506331487174 7.133862744008843E-66 regulation_of_proteolysis GO:0030162 12133 146 49 3 1822 22 2 false 0.25605638215250504 0.25605638215250504 4.197674460173735E-220 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 49 11 1054 11 2 false 0.25664961423853494 0.25664961423853494 2.3625686453162704E-163 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 49 4 2035 17 3 false 0.25683481687048343 0.25683481687048343 0.0 long-chain_fatty_acid_metabolic_process GO:0001676 12133 55 49 1 214 1 1 false 0.2570093457944013 0.2570093457944013 1.7338944688628492E-52 regulation_of_peptidyl-lysine_acetylation GO:2000756 12133 33 49 1 128 1 2 false 0.25781249999999833 0.25781249999999833 2.3260819461485724E-31 embryonic_hindlimb_morphogenesis GO:0035116 12133 24 49 1 93 1 2 false 0.25806451612902936 0.25806451612902936 9.178351962873596E-23 positive_regulation_of_chromosome_organization GO:2001252 12133 49 49 1 847 5 3 false 0.2582092593129238 0.2582092593129238 8.5635846172251E-81 regulation_of_peptidase_activity GO:0052547 12133 276 49 4 1151 11 2 false 0.2582945961815452 0.2582945961815452 1.6233323078676786E-274 early_endosome_to_late_endosome_transport GO:0045022 12133 20 49 1 1423 21 3 false 0.25871429713240945 0.25871429713240945 2.4003835166523446E-45 regulation_of_tight_junction_assembly GO:2000810 12133 8 49 1 58 2 2 false 0.25892316999395243 0.25892316999395243 5.217035699399583E-10 regulation_of_signal_transduction_by_p53_class_mediator GO:1901796 12133 24 49 1 1685 21 2 false 0.2614570540644968 0.2614570540644968 2.665493557536061E-54 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 49 11 1060 11 3 false 0.26183799202912955 0.26183799202912955 8.715047292960447E-163 cyclooxygenase_pathway GO:0019371 12133 11 49 1 42 1 2 false 0.261904761904763 0.261904761904763 2.336142183608801E-10 regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032434 12133 57 49 2 227 4 2 false 0.2626440814523256 0.2626440814523256 4.5524072103258975E-55 positive_regulation_of_DNA_repair GO:0045739 12133 26 49 1 440 5 4 false 0.26359953522455065 0.26359953522455065 1.5959457492821637E-42 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 49 1 1199 10 2 false 0.26362667487014146 0.26362667487014146 9.194442294553035E-70 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 49 14 1304 15 1 false 0.26384779567628136 0.26384779567628136 1.004636319027547E-252 regulation_of_GTPase_activity GO:0043087 12133 277 49 4 1145 11 3 false 0.26401901841799563 0.26401901841799563 2.6919247726004267E-274 negative_regulation_of_transport GO:0051051 12133 243 49 3 4618 34 3 false 0.26457130409966156 0.26457130409966156 0.0 regulation_of_transcription_factor_import_into_nucleus GO:0042990 12133 63 49 2 122 2 2 false 0.26459829291424314 0.26459829291424314 2.784334919854664E-36 biological_regulation GO:0065007 12133 6908 49 35 10446 49 1 false 0.2664184598064752 0.2664184598064752 0.0 peptidyl-tyrosine_modification GO:0018212 12133 191 49 3 623 6 1 false 0.26726249909608946 0.26726249909608946 5.019013158282893E-166 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 49 2 217 5 1 false 0.2674726212094451 0.2674726212094451 4.514459380304185E-47 nuclear_pre-replicative_complex GO:0005656 12133 28 49 1 821 9 4 false 0.26937738622831875 0.26937738622831875 1.2155097168867057E-52 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 49 6 1211 12 2 false 0.2697741556139053 0.2697741556139053 0.0 cell_differentiation_involved_in_kidney_development GO:0061005 12133 40 49 1 2189 17 2 false 0.2699773638274895 0.2699773638274895 2.8675090543885934E-86 response_to_exogenous_dsRNA GO:0043330 12133 19 49 2 36 2 1 false 0.271428571428572 0.271428571428572 1.163129276491937E-10 regulation_of_organelle_organization GO:0033043 12133 519 49 5 2487 17 2 false 0.27145601135381264 0.27145601135381264 0.0 negative_regulation_of_ion_transport GO:0043271 12133 50 49 1 974 6 3 false 0.2716925391506561 0.2716925391506561 4.081641839466338E-85 channel_regulator_activity GO:0016247 12133 66 49 1 10257 49 2 false 0.2717133361475587 0.2717133361475587 1.2576121117294417E-172 regulation_of_tyrosine_phosphorylation_of_STAT_protein GO:0042509 12133 46 49 1 169 1 3 false 0.2721893491124171 0.2721893491124171 1.5655998786815088E-42 viral_infectious_cycle GO:0019058 12133 213 49 9 557 19 1 false 0.27329077620418507 0.27329077620418507 3.455075709157513E-160 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 49 30 4989 43 5 false 0.27334098382029137 0.27334098382029137 0.0 protein_trimerization GO:0070206 12133 22 49 1 288 4 1 false 0.2735563894099662 0.2735563894099662 2.002068954416936E-33 spliceosomal_complex_assembly GO:0000245 12133 38 49 2 259 7 2 false 0.27358107950276844 0.27358107950276844 1.791986159229858E-46 regulation_of_protein_autophosphorylation GO:0031952 12133 21 49 1 870 13 2 false 0.27376504696289966 0.27376504696289966 1.2136753132364896E-42 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 49 7 10311 49 3 false 0.2743052619317133 0.2743052619317133 0.0 actin_filament GO:0005884 12133 48 49 1 3318 22 3 false 0.2750227243376388 0.2750227243376388 1.7385873776725597E-108 adenyl_ribonucleotide_binding GO:0032559 12133 1231 49 12 1645 14 2 false 0.27522899159833286 0.27522899159833286 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 49 12 1650 14 1 false 0.2756795118334633 0.2756795118334633 0.0 CHD-type_complex GO:0090545 12133 16 49 1 58 1 1 false 0.27586206896552057 0.27586206896552057 1.250622453533436E-14 cell_cycle_process GO:0022402 12133 953 49 7 7541 42 2 false 0.27599750429491704 0.27599750429491704 0.0 ion_channel_binding GO:0044325 12133 49 49 1 6397 42 1 false 0.27674630755348745 0.27674630755348745 2.351284918255247E-124 mesenchymal_cell_development GO:0014031 12133 106 49 2 201 2 2 false 0.27686567164176223 0.27686567164176223 7.469742798600782E-60 negative_regulation_of_cell_differentiation GO:0045596 12133 381 49 4 3552 25 4 false 0.27714999198573315 0.27714999198573315 0.0 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 49 4 308 5 2 false 0.27721405994197384 0.27721405994197384 5.66231040699253E-91 response_to_growth_hormone_stimulus GO:0060416 12133 32 49 1 313 3 1 false 0.2772148287696265 0.2772148287696265 1.8848967599686449E-44 DNA_replication_preinitiation_complex GO:0031261 12133 28 49 1 877 10 3 false 0.2783267689614559 0.2783267689614559 1.8592053486968803E-53 blood_vessel_endothelial_cell_migration GO:0043534 12133 53 49 2 100 2 1 false 0.2783838383838401 0.2783838383838401 1.1846448146925151E-29 cell_junction_organization GO:0034330 12133 181 49 2 7663 44 2 false 0.27886027435717775 0.27886027435717775 0.0 plasma_membrane_fusion GO:0045026 12133 26 49 1 93 1 1 false 0.2795698924731146 0.2795698924731146 1.2715108217961999E-23 response_to_interleukin-1 GO:0070555 12133 60 49 2 461 8 1 false 0.27960723947068694 0.27960723947068694 6.955751367016218E-77 regulation_of_vesicle-mediated_transport GO:0060627 12133 196 49 2 6585 35 3 false 0.2798179450819735 0.2798179450819735 0.0 purine-containing_compound_metabolic_process GO:0072521 12133 1232 49 12 5323 43 5 false 0.2798447288848632 0.2798447288848632 0.0 proteasome_complex GO:0000502 12133 62 49 1 9248 49 2 false 0.28141470628279647 0.28141470628279647 4.919625587422917E-161 energy_reserve_metabolic_process GO:0006112 12133 144 49 2 271 2 1 false 0.281426814268146 0.281426814268146 9.26157273052589E-81 fatty_acid_derivative_metabolic_process GO:1901568 12133 52 49 1 7599 48 2 false 0.28152210696927465 0.28152210696927465 1.5249934864539741E-134 regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043516 12133 24 49 1 158 2 3 false 0.28154478755138684 0.28154478755138684 6.672081748801047E-29 vacuole GO:0005773 12133 310 49 3 8213 49 2 false 0.28169148305591124 0.28169148305591124 0.0 positive_regulation_of_purine_nucleotide_biosynthetic_process GO:1900373 12133 77 49 1 273 1 4 false 0.2820512820512513 0.2820512820512513 5.5014514459438226E-70 cytokine_production GO:0001816 12133 362 49 3 4095 21 1 false 0.28231982918024745 0.28231982918024745 0.0 negative_regulation_of_epithelial_to_mesenchymal_transition GO:0010719 12133 12 49 1 79 2 3 false 0.282375851996097 0.282375851996097 1.9527570787405553E-14 leading_edge_membrane GO:0031256 12133 93 49 1 1450 5 2 false 0.2824477679661477 0.2824477679661477 2.320023810279922E-149 endothelium_development GO:0003158 12133 41 49 1 1132 9 1 false 0.28338942471090206 0.28338942471090206 4.316589414530117E-76 ATPase_binding GO:0051117 12133 22 49 1 1005 15 1 false 0.28420878729404736 0.28420878729404736 1.2695671951618567E-45 protein_localization GO:0008104 12133 1434 49 18 1642 19 1 false 0.28476042158881065 0.28476042158881065 3.426309620265761E-270 cytoplasmic_sequestering_of_protein GO:0051220 12133 24 49 1 156 2 2 false 0.28486352357317773 0.28486352357317773 9.286705188012584E-29 thiolester_hydrolase_activity GO:0016790 12133 86 49 1 814 3 1 false 0.28495819906937847 0.28495819906937847 1.2381238582222513E-118 unsaturated_fatty_acid_metabolic_process GO:0033559 12133 61 49 1 214 1 1 false 0.28504672897196576 0.28504672897196576 4.719714770473024E-55 UDP-glucosyltransferase_activity GO:0035251 12133 12 49 1 42 1 2 false 0.2857142857142877 0.2857142857142877 9.043131033324378E-11 mammary_gland_morphogenesis GO:0060443 12133 50 49 1 175 1 2 false 0.2857142857142999 0.2857142857142999 5.092262443140402E-45 nuclear_envelope_organization GO:0006998 12133 27 49 1 819 10 2 false 0.2861731908615669 0.2861731908615669 3.6853965573892743E-51 muscle_organ_development GO:0007517 12133 308 49 3 1966 12 2 false 0.28704640644864154 0.28704640644864154 0.0 regulation_of_steroid_biosynthetic_process GO:0050810 12133 42 49 1 146 1 3 false 0.2876712328767199 0.2876712328767199 1.231507741439357E-37 cellular_response_to_amino_acid_stimulus GO:0071230 12133 32 49 1 584 6 4 false 0.2879565116836151 0.2879565116836151 1.86479058870291E-53 regulation_of_ATPase_activity GO:0043462 12133 26 49 1 1091 14 4 false 0.28803901496974416 0.28803901496974416 5.656765596818151E-53 single-organism_developmental_process GO:0044767 12133 2776 49 17 8064 43 2 false 0.2886774525412622 0.2886774525412622 0.0 polyol_metabolic_process GO:0019751 12133 63 49 1 218 1 1 false 0.2889908256880593 0.2889908256880593 2.003050842244071E-56 response_to_DNA_damage_stimulus GO:0006974 12133 570 49 7 1124 11 1 false 0.2897310875597313 0.2897310875597313 0.0 negative_regulation_of_intracellular_transport GO:0032387 12133 72 49 2 1281 19 3 false 0.28987037831581863 0.28987037831581863 8.445033635932749E-120 cellular_response_to_growth_hormone_stimulus GO:0071378 12133 27 49 1 251 3 2 false 0.29027062833007267 0.29027062833007267 7.510871738156894E-37 protein_sumoylation GO:0016925 12133 32 49 1 578 6 1 false 0.2905465060886204 0.2905465060886204 2.618927943730716E-53 regulation_of_dendrite_development GO:0050773 12133 64 49 1 220 1 2 false 0.2909090909090897 0.2909090909090897 4.1507803256467186E-57 protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:0001844 12133 25 49 1 305 4 3 false 0.2909713158174075 0.2909713158174075 3.3284741778861134E-37 TOR_signaling_cascade GO:0031929 12133 41 49 1 1813 15 1 false 0.2913960317883264 0.2913960317883264 1.3428415689392973E-84 regulation_of_developmental_process GO:0050793 12133 1233 49 8 7209 37 2 false 0.2920280712260255 0.2920280712260255 0.0 unsaturated_fatty_acid_biosynthetic_process GO:0006636 12133 33 49 1 113 1 2 false 0.2920353982300976 0.2920353982300976 2.7853278373724977E-29 potassium_ion_transmembrane_transporter_activity GO:0015079 12133 92 49 1 315 1 3 false 0.2920634920635222 0.2920634920635222 4.7759735730125735E-82 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 49 3 129 4 1 false 0.2921683299761929 0.2921683299761929 2.169508265339551E-38 regulation_of_cartilage_development GO:0061035 12133 42 49 1 993 8 2 false 0.2931837644596759 0.2931837644596759 4.547069063976713E-75 regulation_of_organelle_assembly GO:1902115 12133 25 49 1 807 11 3 false 0.2941527493183427 0.2941527493183427 4.807442974661034E-48 purine_nucleotide_metabolic_process GO:0006163 12133 1208 49 12 1337 12 2 false 0.29438997165971303 0.29438997165971303 1.5771526523631757E-183 nuclear_replication_fork GO:0043596 12133 28 49 1 256 3 3 false 0.2945677975914262 0.2945677975914262 5.235583786811974E-38 response_to_biotic_stimulus GO:0009607 12133 494 49 4 5200 29 1 false 0.29486583192796917 0.29486583192796917 0.0 nuclear_speck GO:0016607 12133 147 49 5 272 7 1 false 0.2954213776191442 0.2954213776191442 6.6218564870724965E-81 nuclear_envelope_reassembly GO:0031468 12133 8 49 1 27 1 1 false 0.2962962962962964 0.2962962962962964 4.504352330439255E-7 negative_regulation_of_peptidyl-tyrosine_phosphorylation GO:0050732 12133 30 49 1 357 4 3 false 0.29718035097343537 0.29718035097343537 2.443461883518979E-44 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 49 3 1256 20 1 false 0.2972985001860414 0.2972985001860414 3.1457660386089413E-171 response_to_endoplasmic_reticulum_stress GO:0034976 12133 111 49 2 1124 11 1 false 0.2973091173610717 0.2973091173610717 1.1256089410717349E-156 activation_of_protein_kinase_activity GO:0032147 12133 247 49 6 417 8 1 false 0.2974544018734687 0.2974544018734687 9.475379918718814E-122 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 49 3 442 4 3 false 0.2981666598174631 0.2981666598174631 2.4953498472018727E-132 response_to_lithium_ion GO:0010226 12133 21 49 1 189 3 1 false 0.29907333662024255 0.29907333662024255 2.5331099887985005E-28 cellular_response_to_insulin_stimulus GO:0032869 12133 185 49 3 276 3 2 false 0.2995355009953646 0.2995355009953646 1.999097443178639E-75 CMG_complex GO:0071162 12133 28 49 1 251 3 4 false 0.29977593241493833 0.29977593241493833 9.388589672695531E-38 termination_of_RNA_polymerase_II_transcription GO:0006369 12133 44 49 1 1385 11 2 false 0.2998352386330013 0.2998352386330013 3.166663017097352E-84 trialkylsulfonium_hydrolase_activity GO:0016802 12133 3 49 1 10 1 1 false 0.2999999999999996 0.2999999999999996 0.008333333333333312 regulation_of_carbohydrate_biosynthetic_process GO:0043255 12133 52 49 1 3097 21 3 false 0.3000568331510064 0.3000568331510064 3.6702105296750396E-114 beta-catenin_binding GO:0008013 12133 54 49 1 6397 42 1 false 0.3003652980250028 0.3003652980250028 8.669980621574108E-135 columnar/cuboidal_epithelial_cell_differentiation GO:0002065 12133 65 49 1 397 2 1 false 0.30099483499983426 0.30099483499983426 2.5390766923657193E-76 membrane_invagination GO:0010324 12133 411 49 6 784 9 1 false 0.3027350111734572 0.3027350111734572 8.658368437912315E-235 intra-Golgi_vesicle-mediated_transport GO:0006891 12133 28 49 1 170 2 1 false 0.3030978071701597 0.3030978071701597 1.1323384985599744E-32 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 49 3 129 4 1 false 0.3036989562351264 0.3036989562351264 2.1037655906323275E-38 regulation_of_striated_muscle_tissue_development GO:0016202 12133 105 49 2 286 3 3 false 0.3047375160051405 0.3047375160051405 4.516187028693684E-81 activation_of_NF-kappaB-inducing_kinase_activity GO:0007250 12133 16 49 1 319 7 5 false 0.3049236110611775 0.3049236110611775 2.6671768240247182E-27 palate_development GO:0060021 12133 62 49 1 3099 18 1 false 0.305649926743253 0.305649926743253 2.0367343521071395E-131 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 49 1 243 5 2 false 0.3063362677733926 0.3063362677733926 1.7559807727942103E-26 regulation_of_cellular_localization GO:0060341 12133 603 49 5 6869 42 3 false 0.30703867045048294 0.30703867045048294 0.0 pathway-restricted_SMAD_protein_phosphorylation GO:0060389 12133 30 49 1 1331 16 2 false 0.30708841767127015 0.30708841767127015 6.939301694879332E-62 nucleoside_binding GO:0001882 12133 1639 49 14 4455 33 3 false 0.3072713425679426 0.3072713425679426 0.0 GINS_complex GO:0000811 12133 28 49 1 244 3 2 false 0.3073808125968294 0.3073808125968294 2.171851500338737E-37 inositol_phosphate_metabolic_process GO:0043647 12133 44 49 1 2783 23 3 false 0.3078897341582314 0.3078897341582314 1.0337589650636944E-97 hindlimb_morphogenesis GO:0035137 12133 33 49 1 107 1 1 false 0.3084112149532806 0.3084112149532806 2.3418627643070335E-28 multicellular_organismal_process GO:0032501 12133 4223 49 22 10446 49 1 false 0.3086269895509093 0.3086269895509093 0.0 chaperone_cofactor-dependent_protein_refolding GO:0070389 12133 5 49 1 30 2 2 false 0.3103448275862064 0.3103448275862064 7.017248396558763E-6 positive_regulation_of_cholesterol_efflux GO:0010875 12133 9 49 1 29 1 3 false 0.3103448275862069 0.3103448275862069 9.985017481269311E-8 regulation_of_lipid_transport GO:0032368 12133 53 49 1 1026 7 2 false 0.3109161815220981 0.3109161815220981 4.3014798118534845E-90 regulation_of_myeloid_cell_differentiation GO:0045637 12133 124 49 2 1656 15 4 false 0.3111543660163276 0.3111543660163276 1.1641273300011644E-190 positive_regulation_of_binding GO:0051099 12133 73 49 1 9050 46 3 false 0.31167038332893116 0.31167038332893116 8.738239425278628E-184 cellular_response_to_mechanical_stimulus GO:0071260 12133 54 49 1 317 2 3 false 0.312123148185073 0.312123148185073 2.439312597229392E-62 hormone_secretion GO:0046879 12133 183 49 1 585 1 3 false 0.3128205128205959 0.3128205128205959 3.893297614002336E-157 PML_body GO:0016605 12133 77 49 3 272 7 1 false 0.3136597958203736 0.3136597958203736 7.662735942565743E-70 positive_regulation_of_cell-matrix_adhesion GO:0001954 12133 26 49 1 152 2 3 false 0.3137852910421309 0.3137852910421309 7.295439891571681E-30 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 49 1 86 1 2 false 0.3139534883720948 0.3139534883720948 6.233113581740502E-23 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 49 12 7451 48 1 false 0.31399106258502885 0.31399106258502885 0.0 negative_regulation_of_developmental_process GO:0051093 12133 463 49 4 4566 28 3 false 0.3144211948267688 0.3144211948267688 0.0 poly(A)_RNA_binding GO:0008143 12133 11 49 1 94 3 2 false 0.31454596998000534 0.31454596998000534 1.4483869139240058E-14 pancreas_development GO:0031016 12133 63 49 1 2873 17 2 false 0.3147657089340288 0.3147657089340288 5.241799089405996E-131 telomere_organization GO:0032200 12133 62 49 1 689 4 1 false 0.31479903148566624 0.31479903148566624 5.719891778584196E-90 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 49 2 53 2 2 false 0.31567489114658837 0.31567489114658837 1.6040955778771873E-15 immune_response-activating_signal_transduction GO:0002757 12133 299 49 7 352 7 2 false 0.3156781412493405 0.3156781412493405 2.8561568566531905E-64 response_to_metal_ion GO:0010038 12133 189 49 3 277 3 1 false 0.3160382985403261 0.3160382985403261 1.2236423246824455E-74 response_to_lipopolysaccharide GO:0032496 12133 183 49 2 970 6 3 false 0.31671666799811804 0.31671666799811804 3.000578332161695E-203 large_ribosomal_subunit GO:0015934 12133 73 49 5 132 7 1 false 0.31711947444326294 0.31711947444326294 5.5437540818743186E-39 protein-DNA_complex GO:0032993 12133 110 49 2 3462 36 1 false 0.3180299366309198 0.3180299366309198 4.3156565695482125E-211 positive_regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902110 12133 37 49 1 1374 14 3 false 0.31887922868684926 0.31887922868684926 1.7604614397711276E-73 sodium_ion_transmembrane_transport GO:0035725 12133 68 49 1 565 3 2 false 0.31984590445849154 0.31984590445849154 1.2033655972436562E-89 neurogenesis GO:0022008 12133 940 49 8 2425 17 2 false 0.31993141158393046 0.31993141158393046 0.0 positive_regulation_of_angiogenesis GO:0045766 12133 71 49 1 774 4 3 false 0.3199883358864871 0.3199883358864871 1.852564870808831E-102 regulation_of_sterol_transport GO:0032371 12133 25 49 1 78 1 2 false 0.3205128205128135 0.3205128205128135 5.8554367810462755E-21 regulation_of_Notch_signaling_pathway GO:0008593 12133 30 49 1 1655 21 2 false 0.32058239660632076 0.32058239660632076 9.430926954379174E-65 histone_deacetylase_complex GO:0000118 12133 50 49 1 3138 24 2 false 0.3208544855759179 0.3208544855759179 6.6201010514053174E-111 positive_regulation_of_innate_immune_response GO:0045089 12133 178 49 4 740 12 4 false 0.3213932231306085 0.3213932231306085 1.4450011889246649E-176 positive_regulation_of_cytokine_production GO:0001819 12133 175 49 2 614 4 3 false 0.32177011693305135 0.32177011693305135 1.2195240299259301E-158 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 49 4 650 11 2 false 0.32245182638235825 0.32245182638235825 6.010278185218431E-162 regulation_of_endothelial_cell_migration GO:0010594 12133 69 49 2 121 2 2 false 0.3231404958677782 0.3231404958677782 1.7052033231209872E-35 negative_regulation_of_growth GO:0045926 12133 169 49 2 2922 20 3 false 0.3234414727055354 0.3234414727055354 1.2080528965902671E-279 regulation_of_generation_of_precursor_metabolites_and_energy GO:0043467 12133 51 49 1 4197 32 2 false 0.32476340642413226 0.32476340642413226 3.5745684624363054E-119 fatty_acid_biosynthetic_process GO:0006633 12133 86 49 1 482 2 3 false 0.32531637925832146 0.32531637925832146 1.4111993524131067E-97 methylation GO:0032259 12133 195 49 2 8027 48 1 false 0.3259606819828682 0.3259606819828682 0.0 response_to_insulin_stimulus GO:0032868 12133 216 49 3 313 3 1 false 0.3272251412333277 0.3272251412333277 1.4650294580642456E-83 renal_system_development GO:0072001 12133 196 49 2 2686 16 2 false 0.3279136428488343 0.3279136428488343 5.871867151923005E-304 cell_body GO:0044297 12133 239 49 2 9983 49 1 false 0.3285120410747178 0.3285120410747178 0.0 regulation_of_pathway-restricted_SMAD_protein_phosphorylation GO:0060393 12133 26 49 1 867 13 3 false 0.32875689046559226 0.32875689046559226 2.407355620871874E-50 ribonucleotide_metabolic_process GO:0009259 12133 1202 49 12 1318 12 2 false 0.3294253574279247 0.3294253574279247 7.680938106405399E-170 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 49 2 2191 23 3 false 0.33044570085254066 0.33044570085254066 2.495063769189982E-191 endopeptidase_activity GO:0004175 12133 470 49 5 586 5 1 false 0.3304924041509254 0.3304924041509254 5.73935751356398E-126 negative_regulation_of_proteolysis GO:0045861 12133 36 49 1 1010 11 3 false 0.33052698173634215 0.33052698173634215 4.887571153196073E-67 monocarboxylic_acid_biosynthetic_process GO:0072330 12133 120 49 1 363 1 2 false 0.3305785123966957 0.3305785123966957 2.0410344299018427E-99 negative_regulation_of_protein_transport GO:0051224 12133 90 49 2 1225 16 3 false 0.33107879393159423 0.33107879393159423 4.959816028960601E-139 anion_transport GO:0006820 12133 242 49 2 833 4 1 false 0.3314761030367242 0.3314761030367242 3.24242391461898E-217 regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902108 12133 39 49 1 1375 14 3 false 0.3328738129113244 0.3328738129113244 1.4191902379759833E-76 regulation_of_RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0045898 12133 5 49 1 15 1 2 false 0.33333333333333326 0.33333333333333326 3.330003330003327E-4 regulation_of_protein_oligomerization GO:0032459 12133 22 49 1 447 8 2 false 0.33437952688975947 0.33437952688975947 9.37826543019211E-38 response_to_ionizing_radiation GO:0010212 12133 98 49 1 293 1 1 false 0.3344709897611002 0.3344709897611002 1.6270830108212225E-80 positive_regulation_of_pathway-restricted_SMAD_protein_phosphorylation GO:0010862 12133 21 49 1 582 11 4 false 0.3349056777221158 0.3349056777221158 6.361190418260006E-39 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 49 13 2560 20 2 false 0.33525766321987377 0.33525766321987377 0.0 GTPase_binding GO:0051020 12133 137 49 3 1005 15 1 false 0.3356839365218056 0.3356839365218056 4.2154504665352884E-173 muscle_cell_differentiation GO:0042692 12133 267 49 3 2218 17 2 false 0.33627742622354384 0.33627742622354384 0.0 negative_regulation_of_intracellular_protein_transport GO:0090317 12133 59 49 2 695 14 4 false 0.3364938619373651 0.3364938619373651 3.676422199192608E-87 epithelial_cell_development GO:0002064 12133 164 49 2 1381 10 2 false 0.3369815169725945 0.3369815169725945 8.032286414365126E-218 blood_coagulation GO:0007596 12133 443 49 5 550 5 3 false 0.33750966997775433 0.33750966997775433 4.662213706291943E-117 regulation_of_protein_export_from_nucleus GO:0046825 12133 24 49 1 188 3 3 false 0.3377315485999676 0.3377315485999676 7.565886554812955E-31 ossification GO:0001503 12133 234 49 2 4095 21 1 false 0.3395785028113847 0.3395785028113847 0.0 purine_NTP-dependent_helicase_activity GO:0070035 12133 98 49 3 140 3 1 false 0.3398185799186785 0.3398185799186785 9.838676628741767E-37 mitochondrial_membrane GO:0031966 12133 359 49 2 1810 6 3 false 0.34056085880485915 0.34056085880485915 0.0 double-strand_break_repair GO:0006302 12133 109 49 2 368 4 1 false 0.3413254930000417 0.3413254930000417 1.714085470943145E-96 regulation_of_locomotion GO:0040012 12133 398 49 3 6714 35 2 false 0.34410881232768564 0.34410881232768564 0.0 cellular_polysaccharide_biosynthetic_process GO:0033692 12133 46 49 1 3415 31 4 false 0.34444808339289246 0.34444808339289246 2.1717472086297818E-105 activation_of_innate_immune_response GO:0002218 12133 155 49 4 362 7 2 false 0.344847859975685 0.344847859975685 1.0665156090103768E-106 regulation_of_mRNA_3'-end_processing GO:0031440 12133 15 49 1 115 3 2 false 0.34509224195542526 0.34509224195542526 4.172184298573769E-19 regulation_of_peptide_secretion GO:0002791 12133 133 49 1 385 1 3 false 0.3454545454544953 0.3454545454544953 3.9095885277458606E-107 NuRD_complex GO:0016581 12133 16 49 1 84 2 3 false 0.3465289730350056 0.3465289730350056 1.5656458332033387E-17 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 49 1 230 2 4 false 0.3466869185493838 0.3466869185493838 2.6271911283291635E-48 regulation_of_dendrite_morphogenesis GO:0048814 12133 40 49 1 209 2 3 false 0.3468899521531183 0.3468899521531183 6.912176535562385E-44 localization_within_membrane GO:0051668 12133 37 49 1 1845 21 1 false 0.3480355277034625 0.3480355277034625 2.8489513256034824E-78 regulation_of_protein_localization_to_nucleus GO:1900180 12133 125 49 2 722 7 3 false 0.34845577364032176 0.34845577364032176 8.18717732691146E-144 circulatory_system_process GO:0003013 12133 307 49 2 1272 5 1 false 0.34892198767379046 0.34892198767379046 1.974873217376429E-304 site_of_polarized_growth GO:0030427 12133 87 49 1 9983 49 1 false 0.34944963967237735 0.34944963967237735 3.5589816347501575E-216 UDP-glycosyltransferase_activity GO:0008194 12133 42 49 1 120 1 1 false 0.35000000000000087 0.35000000000000087 2.37845540100506E-33 poly-purine_tract_binding GO:0070717 12133 14 49 1 40 1 1 false 0.3500000000000021 0.3500000000000021 4.309057712047628E-11 sequence-specific_DNA_binding GO:0043565 12133 1189 49 8 2091 12 1 false 0.3515773536293131 0.3515773536293131 0.0 DNA_alkylation GO:0006305 12133 37 49 2 62 2 1 false 0.35219460602856384 0.35219460602856384 6.784005293429779E-18 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 49 12 5657 44 2 false 0.3525859357193339 0.3525859357193339 0.0 regulation_of_Rac_protein_signal_transduction GO:0035020 12133 23 49 1 278 5 2 false 0.3527802270029553 0.3527802270029553 4.034778444759645E-34 mammary_gland_epithelium_development GO:0061180 12133 68 49 1 661 4 2 false 0.3529181933447077 0.3529181933447077 1.483146375538298E-94 steroid_hormone_receptor_binding GO:0035258 12133 62 49 2 104 2 1 false 0.3530619865571091 0.3530619865571091 4.2931773052216616E-30 macromolecule_methylation GO:0043414 12133 149 49 2 5645 47 3 false 0.3534520639661345 0.3534520639661345 2.745935058350772E-298 neuron_part GO:0097458 12133 612 49 4 9983 49 1 false 0.3535637633361428 0.3535637633361428 0.0 kidney_epithelium_development GO:0072073 12133 57 49 1 684 5 2 false 0.353635757183516 0.353635757183516 1.1272340950274278E-84 peptidyl-serine_modification GO:0018209 12133 127 49 2 623 6 1 false 0.354143444217735 0.354143444217735 3.781982241942545E-136 regulation_of_TOR_signaling_cascade GO:0032006 12133 33 49 1 1607 21 2 false 0.35499112781543685 0.35499112781543685 1.9223233318482158E-69 outer_membrane GO:0019867 12133 112 49 1 4398 17 1 false 0.3555396897696929 0.3555396897696929 7.412183245910406E-226 cellular_carbohydrate_biosynthetic_process GO:0034637 12133 55 49 1 4160 33 3 false 0.3565541838398365 0.3565541838398365 1.6190475925072475E-126 type_B_pancreatic_cell_differentiation GO:0003309 12133 15 49 1 42 1 2 false 0.3571428571428593 0.3571428571428593 1.0134543399415276E-11 connective_tissue_development GO:0061448 12133 156 49 2 1132 9 1 false 0.35812529065974463 0.35812529065974463 2.187737558502385E-196 regulation_of_protein_acetylation GO:1901983 12133 34 49 1 1097 14 2 false 0.3581834321636998 0.3581834321636998 2.1258425781065562E-65 nuclear_import GO:0051170 12133 203 49 3 2389 25 3 false 0.35834265862347836 0.35834265862347836 7.452348105569065E-301 transcription_initiation_from_RNA_polymerase_I_promoter GO:0006361 12133 24 49 1 230 4 2 false 0.35846070254171514 0.35846070254171514 4.4782297667243795E-33 bone_resorption GO:0045453 12133 38 49 1 106 1 2 false 0.35849056603774065 0.35849056603774065 1.1315856884017788E-29 reproductive_structure_development GO:0048608 12133 216 49 2 3110 18 3 false 0.3587704662370528 0.3587704662370528 0.0 midbody GO:0030496 12133 90 49 1 9983 49 1 false 0.35906642809716643 0.35906642809716643 2.5893666131724343E-222 regulation_of_bone_remodeling GO:0046850 12133 23 49 1 64 1 2 false 0.359374999999996 0.359374999999996 6.8156370641429495E-18 growth GO:0040007 12133 646 49 4 10446 49 1 false 0.35967212337930754 0.35967212337930754 0.0 cell_cycle_phase_transition GO:0044770 12133 415 49 4 953 7 1 false 0.3607372204676972 0.3607372204676972 1.4433288987581492E-282 regulation_of_fat_cell_differentiation GO:0045598 12133 57 49 1 923 7 2 false 0.3609132723994107 0.3609132723994107 2.2804165211114662E-92 leukocyte_homeostasis GO:0001776 12133 55 49 1 1628 13 2 false 0.3613912972071943 0.3613912972071943 7.300149261907148E-104 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 49 8 2877 21 6 false 0.36199260919376786 0.36199260919376786 0.0 post-embryonic_development GO:0009791 12133 81 49 1 4373 24 3 false 0.3623145787516187 0.3623145787516187 1.5270071764931075E-174 nuclear_heterochromatin GO:0005720 12133 36 49 1 179 2 2 false 0.36268909672962824 0.36268909672962824 1.2846644689160798E-38 polysaccharide_biosynthetic_process GO:0000271 12133 51 49 1 3550 31 3 false 0.36269209798640933 0.36269209798640933 1.9307363407737106E-115 response_to_amino_acid_stimulus GO:0043200 12133 66 49 1 910 6 3 false 0.3643117743197106 0.3643117743197106 3.0783753457100247E-102 nucleotide-binding_oligomerization_domain_containing_2_signaling_pathway GO:0070431 12133 6 49 1 30 2 1 false 0.3655172413793103 0.3655172413793103 1.684139615174105E-6 protein_import GO:0017038 12133 225 49 3 2509 24 2 false 0.36632698828351606 0.36632698828351606 0.0 nuclear_chromatin GO:0000790 12133 151 49 2 368 3 2 false 0.3665753222464089 0.3665753222464089 1.5117378626822706E-107 growth_hormone_receptor_signaling_pathway GO:0060396 12133 26 49 1 587 10 2 false 0.36658646286090324 0.36658646286090324 7.328929196658047E-46 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 49 11 6103 47 3 false 0.3670288491729156 0.3670288491729156 0.0 nephron_development GO:0072006 12133 79 49 1 3152 18 3 false 0.3675439635670291 0.3675439635670291 9.804100439545243E-160 protein_complex_biogenesis GO:0070271 12133 746 49 9 1525 16 1 false 0.3675472941520209 0.3675472941520209 0.0 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 49 1 415 4 1 false 0.36926596345186424 0.36926596345186424 2.1919403735850567E-61 regulation_of_glucose_metabolic_process GO:0010906 12133 74 49 1 200 1 2 false 0.3699999999999865 0.3699999999999865 9.949659617427537E-57 regulation_of_small_GTPase_mediated_signal_transduction GO:0051056 12133 335 49 5 1759 21 2 false 0.37006109847748997 0.37006109847748997 0.0 protein_dephosphorylation GO:0006470 12133 146 49 2 2505 22 2 false 0.37020421157259975 0.37020421157259975 5.1980515318736674E-241 ameboidal_cell_migration GO:0001667 12133 185 49 2 734 5 1 false 0.37150930236293733 0.37150930236293733 3.1688746703355204E-179 intrinsic_apoptotic_signaling_pathway_by_p53_class_mediator GO:0072332 12133 32 49 1 224 3 2 false 0.3716778918572536 0.3716778918572536 1.6688930470931678E-39 chromatin_remodeling GO:0006338 12133 95 49 1 458 2 1 false 0.3721823550210176 0.3721823550210176 6.184896180355641E-101 reproductive_system_development GO:0061458 12133 216 49 2 2686 16 1 false 0.3728650655682513 0.3728650655682513 0.0 negative_regulation_of_cell_proliferation GO:0008285 12133 455 49 4 2949 20 3 false 0.3730928345753174 0.3730928345753174 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 49 1 341 2 4 false 0.37355528721748876 0.37355528721748876 3.257446469032824E-75 chromosome GO:0005694 12133 592 49 6 3226 27 1 false 0.37445670314571844 0.37445670314571844 0.0 DNA_hypermethylation GO:0044026 12133 3 49 1 8 1 1 false 0.3749999999999999 0.3749999999999999 0.017857142857142835 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 49 3 129 4 1 false 0.376638512482459 0.376638512482459 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 49 3 129 4 1 false 0.376638512482459 0.376638512482459 3.3394798770258706E-38 cell_motility GO:0048870 12133 785 49 6 1249 8 3 false 0.37711487746558725 0.37711487746558725 0.0 positive_regulation_of_cell_death GO:0010942 12133 383 49 4 3330 27 3 false 0.37757478252169163 0.37757478252169163 0.0 potassium_ion_transport GO:0006813 12133 115 49 1 545 2 2 false 0.37779951430121167 0.37779951430121167 2.5935886393871475E-121 nuclear_membrane GO:0031965 12133 157 49 2 4084 34 3 false 0.37819085722998047 0.37819085722998047 2.8056123615014062E-288 glandular_epithelial_cell_development GO:0002068 12133 14 49 1 37 1 2 false 0.378378378378378 0.378378378378378 1.6374419305780848E-10 axonogenesis GO:0007409 12133 421 49 7 483 7 2 false 0.37978420740870644 0.37978420740870644 7.423880338325494E-80 cellular_response_to_acid GO:0071229 12133 38 49 1 1614 20 2 false 0.38082872320051153 0.38082872320051153 1.0205435707228892E-77 SWI/SNF_superfamily-type_complex GO:0070603 12133 58 49 1 4399 36 2 false 0.3810520694330452 0.3810520694330452 1.6616943728575192E-133 membrane_lipid_metabolic_process GO:0006643 12133 90 49 1 606 3 1 false 0.38318473629436844 0.38318473629436844 5.920711661089953E-110 JAK-STAT_cascade GO:0007259 12133 96 49 2 806 11 1 false 0.38406022237055437 0.38406022237055437 3.5358394194592134E-127 sphingolipid_metabolic_process GO:0006665 12133 68 49 1 1861 13 2 false 0.3846142853163666 0.3846142853163666 3.889189985048589E-126 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 49 12 2807 23 3 false 0.38464047391953227 0.38464047391953227 0.0 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 49 4 129 4 1 false 0.3859959910534579 0.3859959910534579 2.104544859412626E-28 regulation_of_microtubule-based_process GO:0032886 12133 89 49 1 6442 35 2 false 0.3862793321661053 0.3862793321661053 3.020423949382438E-203 envelope GO:0031975 12133 641 49 4 9983 49 1 false 0.386565485503091 0.386565485503091 0.0 regulation_of_cellular_component_movement GO:0051270 12133 412 49 3 6475 35 3 false 0.38658737384663 0.38658737384663 0.0 ER-associated_protein_catabolic_process GO:0030433 12133 33 49 1 220 3 1 false 0.3873633278873838 0.3873633278873838 5.451709731275701E-40 cell_projection_membrane GO:0031253 12133 147 49 1 1575 5 2 false 0.38771471217672937 0.38771471217672937 1.960515926193566E-211 regulation_of_mitochondrial_outer_membrane_permeabilization GO:1901028 12133 33 49 1 354 5 4 false 0.3887254926963853 0.3887254926963853 3.0911895026883726E-47 recombinational_repair GO:0000725 12133 48 49 1 416 4 2 false 0.3887821728336801 0.3887821728336801 4.005015877906007E-64 lymphocyte_costimulation GO:0031294 12133 60 49 1 1618 13 2 false 0.38927508996817084 0.38927508996817084 7.286021331162317E-111 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 49 3 129 4 1 false 0.3893613044009125 0.3893613044009125 4.0186961232005657E-38 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 49 7 2370 22 1 false 0.3897065629362958 0.3897065629362958 0.0 protein_insertion_into_membrane GO:0051205 12133 32 49 1 1452 22 3 false 0.3897535143254344 0.3897535143254344 2.4360077014496946E-66 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 49 4 312 4 1 false 0.39079843400740194 0.39079843400740194 8.216510305576978E-69 mitochondrial_outer_membrane_permeabilization GO:0097345 12133 37 49 1 319 4 3 false 0.3908089489637676 0.3908089489637676 2.7662883808425E-49 histone_acetylation GO:0016573 12133 121 49 1 309 1 2 false 0.39158576051776695 0.39158576051776695 3.1224257129978892E-89 in_utero_embryonic_development GO:0001701 12133 295 49 2 471 2 1 false 0.3917875050820852 0.3917875050820852 1.719393530200133E-134 hormone_receptor_binding GO:0051427 12133 122 49 2 918 10 1 false 0.39188013980944975 0.39188013980944975 1.5301276126382055E-155 nucleotide_binding GO:0000166 12133 1997 49 18 2103 18 2 false 0.3926553564122497 0.3926553564122497 1.0169073992212018E-181 peptidyl-tyrosine_phosphorylation GO:0018108 12133 191 49 3 1195 14 2 false 0.39266161427865576 0.39266161427865576 2.9198379950600046E-227 vacuolar_membrane GO:0005774 12133 133 49 1 1670 6 2 false 0.39269612264341297 0.39269612264341297 7.884319611118448E-201 JAK-STAT_cascade_involved_in_growth_hormone_signaling_pathway GO:0060397 12133 22 49 1 100 2 2 false 0.39333333333333476 0.39333333333333476 1.3638719008708662E-22 prostanoid_metabolic_process GO:0006692 12133 24 49 1 61 1 2 false 0.39344262295082544 0.39344262295082544 1.6824333127705597E-17 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 49 1 362 2 4 false 0.3936272784316457 0.3936272784316457 1.827388630734988E-82 multicellular_organismal_development GO:0007275 12133 3069 49 18 4373 24 2 false 0.39563220523856013 0.39563220523856013 0.0 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 49 1 162 2 5 false 0.39613526570044455 0.39613526570044455 7.1760328941400225E-37 endosomal_transport GO:0016197 12133 133 49 2 2454 25 2 false 0.39649472801775476 0.39649472801775476 7.966947585336105E-224 positive_regulation_of_cell-substrate_adhesion GO:0010811 12133 54 49 1 242 2 3 false 0.3972086005280846 0.3972086005280846 2.622957998247209E-55 regulation_of_intracellular_transport GO:0032386 12133 276 49 4 1731 20 3 false 0.39833908168056914 0.39833908168056914 0.0 DNA_polymerase_activity GO:0034061 12133 49 49 1 123 1 1 false 0.3983739837398253 0.3983739837398253 1.6565752525035403E-35 negative_regulation_of_endothelial_cell_migration GO:0010596 12133 23 49 1 103 2 3 false 0.39843898724537685 0.39843898724537685 1.8683564084133473E-23 purine_nucleoside_metabolic_process GO:0042278 12133 1054 49 11 1257 12 2 false 0.39885282313987347 0.39885282313987347 1.399683863089717E-240 positive_regulation_of_nucleotide_biosynthetic_process GO:0030810 12133 77 49 1 1402 9 4 false 0.3994350035379875 0.3994350035379875 6.104501177954134E-129 growth_cone GO:0030426 12133 85 49 1 711 4 3 false 0.39976744792761715 0.39976744792761715 2.0579726954820752E-112 regulation_of_mitochondrion_organization GO:0010821 12133 64 49 1 661 5 2 false 0.39999257858682696 0.39999257858682696 9.542606350434685E-91 positive_regulation_of_adenylate_cyclase_activity GO:0045762 12133 52 49 1 130 1 5 false 0.3999999999999939 0.3999999999999939 1.4124265749856537E-37 myoblast_fusion GO:0007520 12133 18 49 1 45 1 2 false 0.39999999999999963 0.39999999999999963 5.827898107063272E-13 positive_regulation_of_transport GO:0051050 12133 413 49 4 4769 37 3 false 0.4004915719900959 0.4004915719900959 0.0 chondrocyte_differentiation GO:0002062 12133 64 49 1 2165 17 2 false 0.4007290401740005 0.4007290401740005 1.1028829850497335E-124 positive_regulation_of_histone_modification GO:0031058 12133 40 49 1 963 12 4 false 0.4007549355811692 0.4007549355811692 8.380486405163906E-72 cell-substrate_junction GO:0030055 12133 133 49 1 588 2 1 false 0.40151699521389206 0.40151699521389206 7.571970094553597E-136 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 49 13 7461 48 2 false 0.40253629146625913 0.40253629146625913 0.0 regulation_of_epithelial_cell_differentiation GO:0030856 12133 73 49 1 1316 9 3 false 0.4026397448236282 0.4026397448236282 6.734227229468951E-122 interaction_with_host GO:0051701 12133 387 49 12 417 12 2 false 0.40314980498956515 0.40314980498956515 1.9217516081652173E-46 cellular_potassium_ion_transport GO:0071804 12133 92 49 1 7541 42 2 false 0.4036726646534511 0.4036726646534511 4.105440908779901E-215 Rac_GTPase_binding GO:0048365 12133 21 49 1 52 1 1 false 0.4038461538461552 0.4038461538461552 5.208555404055776E-15 activin_receptor_signaling_pathway GO:0032924 12133 28 49 1 232 4 1 false 0.40432366190849006 0.40432366190849006 9.723452082207629E-37 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 49 3 442 4 3 false 0.4048741468010038 0.4048741468010038 4.945935388068452E-131 regulation_of_cytokine_production GO:0001817 12133 323 49 3 1562 11 2 false 0.4052024592804937 0.4052024592804937 0.0 protein_dimerization_activity GO:0046983 12133 779 49 6 6397 42 1 false 0.4052377407948718 0.4052377407948718 0.0 urogenital_system_development GO:0001655 12133 231 49 2 2686 16 1 false 0.4059947455968057 0.4059947455968057 0.0 regulation_of_synaptic_plasticity GO:0048167 12133 82 49 1 2092 13 2 false 0.40627735725963054 0.40627735725963054 1.2289450112441968E-149 T_cell_costimulation GO:0031295 12133 59 49 1 145 1 2 false 0.40689655172412764 0.40689655172412764 4.1748509083178786E-42 negative_regulation_of_protein_modification_process GO:0031400 12133 328 49 4 2431 24 3 false 0.40969971568001745 0.40969971568001745 0.0 positive_regulation_of_epithelial_cell_migration GO:0010634 12133 62 49 1 268 2 3 false 0.409832858180916 0.409832858180916 1.921249223488317E-62 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 49 11 1007 11 2 false 0.4100554234513058 0.4100554234513058 1.4040993054667365E-118 regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001242 12133 31 49 1 193 3 2 false 0.41038439627814294 0.41038439627814294 1.4758328099403201E-36 protein_binding_transcription_factor_activity GO:0000988 12133 488 49 3 10311 49 3 false 0.4112134176058432 0.4112134176058432 0.0 ephrin_receptor_signaling_pathway GO:0048013 12133 30 49 1 586 10 1 false 0.4112213462594389 0.4112213462594389 5.184030943639595E-51 regulation_of_cholesterol_efflux GO:0010874 12133 14 49 1 34 1 2 false 0.41176470588235115 0.41176470588235115 7.184033766567843E-10 rRNA_processing GO:0006364 12133 102 49 2 231 3 3 false 0.4123587443503201 0.4123587443503201 2.6685808966337758E-68 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 49 1 222 3 3 false 0.41341011929244453 0.41341011929244453 2.5456303013282065E-42 peptidyl-threonine_modification GO:0018210 12133 53 49 1 623 6 1 false 0.4147484796805962 0.4147484796805962 3.249714987562728E-78 tissue_remodeling GO:0048771 12133 103 49 1 4095 21 1 false 0.41508525947465824 0.41508525947465824 3.129128065207337E-208 regulation_of_mitosis GO:0007088 12133 100 49 1 611 3 4 false 0.4155861217792173 0.4155861217792173 1.2375244614825155E-117 regulation_of_type_I_interferon-mediated_signaling_pathway GO:0060338 12133 24 49 1 282 6 3 false 0.4164944582899177 0.4164944582899177 2.655253961660049E-35 amino_acid_transport GO:0006865 12133 78 49 1 475 3 2 false 0.41689106487143135 0.41689106487143135 1.5149917368485561E-91 negative_regulation_of_cell_adhesion GO:0007162 12133 78 49 1 2936 20 3 false 0.41742348825500597 0.41742348825500597 1.0404104256027157E-155 cell_differentiation GO:0030154 12133 2154 49 17 2267 17 1 false 0.41795295253275927 0.41795295253275927 2.602261335719434E-194 cellular_response_to_external_stimulus GO:0071496 12133 182 49 2 1046 8 1 false 0.41844690178612376 0.41844690178612376 3.4557864180082167E-209 neuron_migration GO:0001764 12133 89 49 1 1360 8 2 false 0.4189351044380588 0.4189351044380588 4.085890514650152E-142 regulation_of_neurological_system_process GO:0031644 12133 172 49 1 1040 3 2 false 0.418954055507799 0.418954055507799 8.112526166227745E-202 potassium_ion_transmembrane_transport GO:0071805 12133 92 49 1 556 3 2 false 0.41941821311218713 0.41941821311218713 1.0312185181817459E-107 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 49 11 1006 11 2 false 0.4195465262750401 0.4195465262750401 2.1893990019353197E-116 peptidyl-serine_phosphorylation GO:0018105 12133 121 49 2 1201 14 2 false 0.4198820979766479 0.4198820979766479 1.0029038835537004E-169 response_to_hypoxia GO:0001666 12133 200 49 2 2540 18 2 false 0.42040534644980865 0.42040534644980865 2.6634431659671552E-303 XY_body GO:0001741 12133 8 49 1 19 1 2 false 0.4210526315789468 0.4210526315789468 1.3230663385462133E-5 regulation_of_growth GO:0040008 12133 447 49 3 6651 35 2 false 0.4211674285782234 0.4211674285782234 0.0 rRNA_binding GO:0019843 12133 29 49 1 763 14 1 false 0.42146465790750165 0.42146465790750165 3.8668021308986908E-53 ion_binding GO:0043167 12133 4448 49 24 8962 46 1 false 0.4215614614196961 0.4215614614196961 0.0 DNA_biosynthetic_process GO:0071897 12133 268 49 3 3979 35 3 false 0.4227053218481421 0.4227053218481421 0.0 heterochromatin GO:0000792 12133 69 49 1 287 2 1 false 0.42367388708848075 0.42367388708848075 3.2461209792267802E-68 interferon-gamma-mediated_signaling_pathway GO:0060333 12133 66 49 2 330 7 2 false 0.42412307492535983 0.42412307492535983 3.5052495329479947E-71 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 49 3 504 3 1 false 0.42439486586449415 0.42439486586449415 6.011520399617331E-122 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 49 1 389 2 3 false 0.4253703654626078 0.4253703654626078 8.074632425282073E-93 muscle_structure_development GO:0061061 12133 413 49 3 3152 18 2 false 0.42606832080408286 0.42606832080408286 0.0 cellular_response_to_nutrient_levels GO:0031669 12133 110 49 1 258 1 2 false 0.4263565891472961 0.4263565891472961 7.13814980036364E-76 regulation_of_neuronal_synaptic_plasticity GO:0048168 12133 35 49 1 82 1 1 false 0.4268292682926716 0.4268292682926716 5.621776882740478E-24 RNA-directed_DNA_polymerase_activity GO:0003964 12133 21 49 1 49 1 1 false 0.4285714285714328 0.4285714285714328 2.560824792650333E-14 nuclear_export GO:0051168 12133 116 49 3 688 14 2 false 0.42899660363320025 0.42899660363320025 6.892155989004194E-135 muscle_tissue_development GO:0060537 12133 295 49 3 1132 9 1 false 0.42911927523163174 0.42911927523163174 3.412889797328503E-281 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 49 10 5558 45 3 false 0.4291812058039757 0.4291812058039757 0.0 ion_transmembrane_transport GO:0034220 12133 556 49 3 970 4 2 false 0.42921600957535105 0.42921600957535105 1.3121997139332702E-286 cellular_polysaccharide_metabolic_process GO:0044264 12133 67 49 1 5670 47 3 false 0.4293498920567179 0.4293498920567179 1.7454278483133037E-157 maintenance_of_location_in_cell GO:0051651 12133 100 49 1 7542 42 3 false 0.430015429972591 0.430015429972591 3.2184799576057033E-230 neuronal_cell_body GO:0043025 12133 215 49 2 621 4 2 false 0.4303562212599728 0.4303562212599728 3.1563152846547707E-173 positive_regulation_of_hydrolase_activity GO:0051345 12133 562 49 5 2891 22 3 false 0.4305273328680854 0.4305273328680854 0.0 protein_N-terminus_binding GO:0047485 12133 85 49 1 6397 42 1 false 0.4308637420989614 0.4308637420989614 1.5319897739448716E-195 polysaccharide_metabolic_process GO:0005976 12133 74 49 1 6221 47 2 false 0.4313716777475003 0.4313716777475003 9.187602528598046E-174 regulation_of_alternative_mRNA_splicing,_via_spliceosome GO:0000381 12133 16 49 1 37 1 2 false 0.43243243243243207 0.43243243243243207 7.76652299088412E-11 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 49 11 1002 11 3 false 0.43325241774625967 0.43325241774625967 5.68242981185093E-113 cyclic_nucleotide_biosynthetic_process GO:0009190 12133 151 49 1 348 1 2 false 0.4339080459770588 0.4339080459770588 8.533554981861938E-103 nervous_system_development GO:0007399 12133 1371 49 9 2686 16 1 false 0.4346664612423293 0.4346664612423293 0.0 cAMP_biosynthetic_process GO:0006171 12133 124 49 1 284 1 3 false 0.4366197183098948 0.4366197183098948 6.647675853046176E-84 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 49 2 506 4 3 false 0.4367546478911092 0.4367546478911092 1.5079927652081954E-141 hemostasis GO:0007599 12133 447 49 5 527 5 1 false 0.4375225590465359 0.4375225590465359 7.174896528140087E-97 striated_muscle_cell_differentiation GO:0051146 12133 203 49 3 267 3 1 false 0.437929995648414 0.437929995648414 2.4098375851666058E-63 execution_phase_of_apoptosis GO:0097194 12133 103 49 1 7541 42 2 false 0.43965617283242114 0.43965617283242114 8.404030944176242E-236 regulation_of_lipid_biosynthetic_process GO:0046890 12133 85 49 1 3279 22 3 false 0.43993419979657816 0.43993419979657816 1.2266874982723732E-170 arachidonic_acid_metabolic_process GO:0019369 12133 33 49 1 75 1 3 false 0.4400000000000015 0.4400000000000015 4.917588428220888E-22 negative_regulation_of_MAP_kinase_activity GO:0043407 12133 62 49 2 343 8 4 false 0.44013087048972055 0.44013087048972055 7.269028156110723E-70 negative_regulation_of_blood_vessel_endothelial_cell_migration GO:0043537 12133 15 49 1 60 2 3 false 0.44067796610169824 0.44067796610169824 1.8799081160635002E-14 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 49 3 129 4 1 false 0.44160540978890245 0.44160540978890245 1.1512773005265922E-37 meiosis GO:0007126 12133 122 49 2 1243 15 2 false 0.4418538516693392 0.4418538516693392 1.368721434688107E-172 response_to_salt_stress GO:0009651 12133 19 49 1 43 1 1 false 0.44186046511627686 0.44186046511627686 1.2492622608986976E-12 condensed_nuclear_chromosome GO:0000794 12133 64 49 1 363 3 2 false 0.44214477614646513 0.44214477614646513 6.85090242714841E-73 small_molecule_metabolic_process GO:0044281 12133 2423 49 16 2877 18 1 false 0.442229573108732 0.442229573108732 0.0 peptidase_activity GO:0008233 12133 614 49 5 2556 18 1 false 0.4423115030274599 0.4423115030274599 0.0 establishment_or_maintenance_of_cell_polarity GO:0007163 12133 104 49 1 7541 42 1 false 0.4428202546744652 0.4428202546744652 1.175072893510937E-237 NF-kappaB-inducing_kinase_activity GO:0004704 12133 21 49 1 301 8 2 false 0.4432642935021812 0.4432642935021812 9.301787616944151E-33 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 49 3 217 5 1 false 0.44344748989608196 0.44344748989608196 1.2933579260360868E-64 small_GTPase_regulator_activity GO:0005083 12133 234 49 2 351 2 1 false 0.44380952380958166 0.44380952380958166 2.0747066283815493E-96 positive_regulation_of_cyclic_nucleotide_metabolic_process GO:0030801 12133 80 49 1 180 1 3 false 0.44444444444442294 0.44444444444442294 3.3247573319336413E-53 cellular_response_to_peptide GO:1901653 12133 247 49 3 625 6 3 false 0.44568697227027837 0.44568697227027837 2.2359681686760748E-181 pre-replicative_complex GO:0036387 12133 28 49 1 110 2 1 false 0.4460383653044162 0.4460383653044162 9.125355053770069E-27 glandular_epithelial_cell_differentiation GO:0002067 12133 29 49 1 65 1 1 false 0.4461538461538422 0.4461538461538422 3.9878950035701625E-19 positive_regulation_of_organelle_organization GO:0010638 12133 217 49 2 2191 15 3 false 0.4463042856565845 0.4463042856565845 1.6765812392172608E-306 RNA_polyadenylation GO:0043631 12133 25 49 1 98 2 1 false 0.44708605091520026 0.44708605091520026 7.35522495115787E-24 positive_regulation_of_ERK1_and_ERK2_cascade GO:0070374 12133 73 49 2 350 7 3 false 0.44772601592579625 0.44772601592579625 2.793376924439548E-77 positive_regulation_of_lymphocyte_activation GO:0051251 12133 188 49 1 419 1 3 false 0.44868735083532396 0.44868735083532396 1.71987955515036E-124 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 49 10 2595 20 2 false 0.44873406337138966 0.44873406337138966 0.0 positive_regulation_of_T_cell_activation GO:0050870 12133 145 49 1 323 1 3 false 0.4489164086687781 0.4489164086687781 7.1027996669547384E-96 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 49 2 415 4 3 false 0.44891723205655776 0.44891723205655776 9.462933237946419E-117 mitochondrial_outer_membrane GO:0005741 12133 96 49 1 372 2 2 false 0.4500478219285001 0.4500478219285001 1.1824719222700171E-91 organelle_outer_membrane GO:0031968 12133 110 49 1 9084 49 4 false 0.45040040612460047 0.45040040612460047 1.1973077012984011E-257 tetrapyrrole_binding GO:0046906 12133 79 49 1 4407 33 2 false 0.4507068901433263 0.4507068901433263 2.34302834047957E-171 organ_development GO:0048513 12133 1929 49 12 3099 18 2 false 0.4507890825269975 0.4507890825269975 0.0 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 49 1 1056 8 3 false 0.4509652747343786 0.4509652747343786 4.764817151311381E-118 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 49 2 201 8 3 false 0.4512913830886305 0.4512913830886305 2.854176062301069E-41 glomerular_epithelial_cell_differentiation GO:0072311 12133 14 49 1 31 1 2 false 0.45161290322580533 0.45161290322580533 3.770987549047572E-9 regulation_of_membrane_potential GO:0042391 12133 216 49 1 478 1 1 false 0.4518828451882676 0.4518828451882676 3.2092050959317294E-142 central_nervous_system_development GO:0007417 12133 571 49 4 2686 16 2 false 0.4522470331790744 0.4522470331790744 0.0 spindle_pole GO:0000922 12133 87 49 1 3232 22 3 false 0.45245224323419997 0.45245224323419997 3.214023535487519E-173 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 49 1 242 3 2 false 0.45380988306300024 0.45380988306300024 2.220259827778367E-49 brain_development GO:0007420 12133 420 49 3 2904 17 3 false 0.4549608662292519 0.4549608662292519 0.0 female_gamete_generation GO:0007292 12133 65 49 1 355 3 1 false 0.45589588812466025 0.45589588812466025 7.344010792750422E-73 stem_cell_development GO:0048864 12133 191 49 2 1273 10 2 false 0.4563526101945724 0.4563526101945724 5.877761968359015E-233 positive_regulation_of_Rac_GTPase_activity GO:0032855 12133 32 49 1 70 1 1 false 0.45714285714285513 0.45714285714285513 1.148913099666628E-20 protein_kinase_C_binding GO:0005080 12133 39 49 1 341 5 1 false 0.45724660303096243 0.45724660303096243 3.262596721977534E-52 positive_regulation_of_cAMP_metabolic_process GO:0030816 12133 71 49 1 155 1 4 false 0.4580645161290261 0.4580645161290261 5.885583975701031E-46 single-organism_metabolic_process GO:0044710 12133 2877 49 18 8027 48 1 false 0.45885707870709846 0.45885707870709846 0.0 insulin_receptor_signaling_pathway GO:0008286 12133 151 49 3 617 10 2 false 0.45903387270487195 0.45903387270487195 2.0667953594506098E-148 negative_regulation_of_transferase_activity GO:0051348 12133 180 49 2 2118 18 3 false 0.46051865111754975 0.46051865111754975 1.0892582554699503E-266 cellular_component_organization GO:0016043 12133 3745 49 31 3839 31 1 false 0.46229321004409285 0.46229321004409285 4.153510440731863E-191 apoptotic_nuclear_changes GO:0030262 12133 37 49 1 80 1 1 false 0.4625000000000024 0.4625000000000024 1.1618654074855353E-23 mRNA_processing GO:0006397 12133 374 49 10 763 19 2 false 0.464986164281585 0.464986164281585 8.270510506831645E-229 peptidyl-threonine_phosphorylation GO:0018107 12133 52 49 1 1196 14 2 false 0.46517197015922485 0.46517197015922485 2.255232718606443E-92 negative_regulation_of_protein_catabolic_process GO:0042177 12133 43 49 1 851 12 4 false 0.4654696488700384 0.4654696488700384 1.831793147974944E-73 male_sex_differentiation GO:0046661 12133 105 49 1 3074 18 2 false 0.46599342917338465 0.46599342917338465 4.0305150218166505E-198 mitochondrial_membrane_organization GO:0007006 12133 62 49 1 924 9 2 false 0.4663053620506777 0.4663053620506777 3.431124286579491E-98 cell-matrix_adhesion GO:0007160 12133 130 49 2 190 2 1 false 0.46700083542186166 0.46700083542186166 5.558763172566491E-51 tubulin_binding GO:0015631 12133 150 49 1 556 2 1 false 0.46713980167219776 0.46713980167219776 4.293395323631497E-140 monocarboxylic_acid_metabolic_process GO:0032787 12133 287 49 1 614 1 1 false 0.4674267100978451 0.4674267100978451 1.6797243192352778E-183 regulation_of_cell_morphogenesis_involved_in_differentiation GO:0010769 12133 167 49 2 879 8 3 false 0.46750289536290895 0.46750289536290895 7.212819447877608E-185 peptidyl-asparagine_modification GO:0018196 12133 62 49 1 623 6 1 false 0.4682762772517688 0.4682762772517688 4.0133790136329974E-87 ruffle_membrane GO:0032587 12133 56 49 1 207 2 3 false 0.46883354439284075 0.46883354439284075 5.291580376353652E-52 protein_heterodimerization_activity GO:0046982 12133 317 49 3 779 6 1 false 0.470097824261235 0.470097824261235 8.49214053182804E-228 regulation_of_cell_cycle GO:0051726 12133 659 49 4 6583 35 2 false 0.47011001463159585 0.47011001463159585 0.0 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 49 11 2643 20 1 false 0.4705339985046526 0.4705339985046526 0.0 neuron_differentiation GO:0030182 12133 812 49 7 2154 17 2 false 0.4734989243219399 0.4734989243219399 0.0 negative_regulation_of_protein_serine/threonine_kinase_activity GO:0071901 12133 98 49 2 757 12 3 false 0.4737024068360924 0.4737024068360924 4.731915708065017E-126 protein_N-linked_glycosylation GO:0006487 12133 65 49 1 137 1 1 false 0.4744525547445422 0.4744525547445422 1.0074837927766115E-40 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 49 4 305 7 2 false 0.47465985127301114 0.47465985127301114 3.640759676212702E-91 tube_morphogenesis GO:0035239 12133 260 49 2 2815 17 3 false 0.474886997187187 0.474886997187187 0.0 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 49 7 1079 15 3 false 0.47591057262193404 0.47591057262193404 5.98264E-319 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 49 26 6094 48 2 false 0.47605684778390395 0.47605684778390395 0.0 dendrite_development GO:0016358 12133 111 49 1 3152 18 3 false 0.476434026969192 0.476434026969192 5.679983906241444E-208 gland_morphogenesis GO:0022612 12133 105 49 1 2812 17 3 false 0.4773367247237676 0.4773367247237676 5.511647482343512E-194 positive_regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030804 12133 75 49 1 157 1 4 false 0.4777070063694132 0.4777070063694132 1.0054402594300752E-46 regulation_of_synaptic_transmission GO:0050804 12133 146 49 1 527 2 2 false 0.4777093960362299 0.4777093960362299 2.2122601830133273E-134 mRNA_polyadenylation GO:0006378 12133 24 49 1 87 2 2 false 0.47794707297515227 0.47794707297515227 5.836090149000628E-22 regulation_of_cell_proliferation GO:0042127 12133 999 49 6 6358 35 2 false 0.4783861125941312 0.4783861125941312 0.0 regulation_of_apoptotic_process GO:0042981 12133 1019 49 11 1381 14 2 false 0.4785070399527773 0.4785070399527773 0.0 regulation_of_systemic_arterial_blood_pressure GO:0003073 12133 56 49 1 117 1 1 false 0.4786324786324643 0.4786324786324643 9.090542259133476E-35 T_cell_receptor_signaling_pathway GO:0050852 12133 88 49 3 112 3 1 false 0.4814671814671709 0.4814671814671709 5.828412725788921E-25 regulation_of_protein_import_into_nucleus GO:0042306 12133 121 49 2 248 3 4 false 0.48178456187070967 0.48178456187070967 4.6955049394038436E-74 cell_junction_assembly GO:0034329 12133 159 49 2 1406 14 2 false 0.48181101135819004 0.48181101135819004 9.423437086545545E-215 endocrine_system_development GO:0035270 12133 108 49 1 2686 16 1 false 0.4823759612644021 0.4823759612644021 5.316219465834033E-196 appendage_development GO:0048736 12133 114 49 1 3347 19 3 false 0.48326900146340634 0.48326900146340634 2.7546219462070674E-215 appendage_morphogenesis GO:0035107 12133 107 49 1 2812 17 3 false 0.483881983173073 0.483881983173073 8.534046950129346E-197 multicellular_organismal_homeostasis GO:0048871 12133 128 49 1 4332 22 2 false 0.4839090752544215 0.4839090752544215 8.184767611609268E-250 response_to_inorganic_substance GO:0010035 12133 277 49 3 2369 22 1 false 0.48415926228208284 0.48415926228208284 0.0 regulation_of_viral_reproduction GO:0050792 12133 101 49 1 6451 42 3 false 0.4856784207314819 0.4856784207314819 3.49743359338843E-225 protein_oligomerization GO:0051259 12133 288 49 4 743 9 1 false 0.4863708512911262 0.4863708512911262 1.196705520432063E-214 sex_chromatin GO:0001739 12133 18 49 1 37 1 2 false 0.4864864864864845 0.4864864864864845 5.658466750501292E-11 coated_vesicle GO:0030135 12133 202 49 1 712 2 1 false 0.4872113971462813 0.4872113971462813 1.1363731817938802E-183 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 49 1 2735 23 4 false 0.4873733617086872 0.4873733617086872 2.836340851870023E-153 regulation_of_DNA_repair GO:0006282 12133 46 49 1 508 7 3 false 0.48755868889829823 0.48755868889829823 1.525242689490639E-66 Rac_protein_signal_transduction GO:0016601 12133 33 49 1 365 7 1 false 0.4878448822203272 0.4878448822203272 1.0734561739608448E-47 positive_regulation_of_Ras_GTPase_activity GO:0032320 12133 131 49 2 266 3 2 false 0.48867989011984425 0.48867989011984425 1.778046339762686E-79 cellular_response_to_molecule_of_bacterial_origin GO:0071219 12133 101 49 2 205 3 2 false 0.48897102995951797 0.48897102995951797 3.5711217717453676E-61 K63-linked_polyubiquitin_binding GO:0070530 12133 7 49 1 25 2 1 false 0.4900000000000001 0.4900000000000001 2.08029956313708E-6 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 49 3 5157 30 3 false 0.49041398880672443 0.49041398880672443 0.0 histone_binding GO:0042393 12133 102 49 1 6397 42 1 false 0.49200103947674145 0.49200103947674145 1.3332295224304937E-226 negative_regulation_of_NF-kappaB_transcription_factor_activity GO:0032088 12133 51 49 2 103 3 1 false 0.4926463520138246 0.4926463520138246 1.2633713261943138E-30 epithelial_cell_migration GO:0010631 12133 130 49 2 185 2 2 false 0.4926556991774518 0.4926556991774518 1.9916445787710798E-48 positive_regulation_of_lyase_activity GO:0051349 12133 64 49 1 1165 12 3 false 0.49406261752769576 0.49406261752769576 4.208539259642897E-107 Golgi_vesicle_transport GO:0048193 12133 170 49 2 2599 25 3 false 0.49413762442862097 0.49413762442862097 6.28157499519694E-272 regulation_of_cytoskeleton_organization GO:0051493 12133 250 49 2 955 6 2 false 0.49416462896839314 0.49416462896839314 1.2229840665192896E-237 dendritic_spine GO:0043197 12133 121 49 1 596 3 3 false 0.4944275249247668 0.4944275249247668 6.183643418341279E-130 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 49 1 676 8 2 false 0.49469495571096733 0.49469495571096733 2.737610529852072E-82 bone_remodeling GO:0046849 12133 51 49 1 103 1 1 false 0.4951456310679525 0.4951456310679525 1.2633713261943138E-30 signal_transducer_activity GO:0004871 12133 1070 49 8 3547 25 2 false 0.4956167951395981 0.4956167951395981 0.0 ATP-dependent_RNA_helicase_activity GO:0004004 12133 20 49 1 99 3 3 false 0.4958271968581023 0.4958271968581023 2.332161908415525E-21 nuclear_chromosome_part GO:0044454 12133 244 49 3 2878 31 3 false 0.49633648648677664 0.49633648648677664 0.0 regulation_of_Rho_protein_signal_transduction GO:0035023 12133 149 49 3 299 5 2 false 0.4968433269833272 0.4968433269833272 2.1331125641940734E-89 mammary_gland_development GO:0030879 12133 125 49 1 251 1 1 false 0.4980079681274882 0.4980079681274882 5.503793662567663E-75 negative_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043124 12133 32 49 1 297 6 3 false 0.49852103903874595 0.49852103903874595 1.1075051157890655E-43 positive_regulation_of_cell_growth GO:0030307 12133 79 49 1 2912 25 4 false 0.4986681459345088 0.4986681459345088 5.548863790318827E-157 cation_channel_activity GO:0005261 12133 216 49 1 433 1 2 false 0.4988452655890016 0.4988452655890016 1.1777872542675005E-129 cellular_response_to_steroid_hormone_stimulus GO:0071383 12133 91 49 1 706 5 4 false 0.4994612790710555 0.4994612790710555 3.3411431818141285E-117 immune_effector_process GO:0002252 12133 445 49 4 1618 13 1 false 0.49950072882273294 0.49950072882273294 0.0 regulation_of_cholesterol_transport GO:0032374 12133 25 49 1 50 1 2 false 0.4999999999999955 0.4999999999999955 7.910728602448565E-15 glycogen_(starch)_synthase_activity GO:0004373 12133 6 49 1 12 1 1 false 0.4999999999999995 0.4999999999999995 0.0010822510822510805 aggresome_assembly GO:0070842 12133 5 49 1 10 1 1 false 0.4999999999999995 0.4999999999999995 0.003968253968253954 DNA_topoisomerase_type_I_activity GO:0003917 12133 4 49 1 8 1 1 false 0.4999999999999997 0.4999999999999997 0.014285714285714268 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 49 1 195 2 4 false 0.5002379064234905 0.5002379064234905 1.081664723883568E-50 virus-host_interaction GO:0019048 12133 355 49 12 588 19 2 false 0.5008282008780844 0.5008282008780844 1.0104535019427035E-170 cellular_component_movement GO:0006928 12133 1012 49 6 7541 42 1 false 0.5023043472350324 0.5023043472350324 0.0 cell_activation GO:0001775 12133 656 49 4 7541 42 1 false 0.5027369029830706 0.5027369029830706 0.0 positive_regulation_of_blood_vessel_endothelial_cell_migration GO:0043536 12133 21 49 1 71 2 3 false 0.5070422535211306 0.5070422535211306 1.8270708961531386E-18 negative_regulation_of_cell_death GO:0060548 12133 567 49 5 3054 25 3 false 0.5071942269016079 0.5071942269016079 0.0 catalytic_step_2_spliceosome GO:0071013 12133 76 49 4 151 7 3 false 0.5073922278319152 0.5073922278319152 5.422089502503699E-45 regulation_of_DNA_replication GO:0006275 12133 92 49 1 2913 22 3 false 0.5076789240386413 0.5076789240386413 1.0142928746758388E-176 positive_regulation_of_autophagy GO:0010508 12133 25 49 1 191 5 3 false 0.5080847674166012 0.5080847674166012 7.553410603891602E-32 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 49 3 129 4 1 false 0.509331319050262 0.509331319050262 8.751505837166389E-37 negative_regulation_of_cell_projection_organization GO:0031345 12133 71 49 1 936 9 3 false 0.5099023996497324 0.5099023996497324 1.4196570412903908E-108 extrinsic_apoptotic_signaling_pathway GO:0097191 12133 77 49 1 2096 19 2 false 0.5104508061291675 0.5104508061291675 1.0680041317028193E-142 response_to_peptide_hormone_stimulus GO:0043434 12133 313 49 3 619 5 2 false 0.5106353324086704 0.5106353324086704 1.4916788604957572E-185 telomere_maintenance GO:0000723 12133 61 49 1 888 10 3 false 0.5110212373281687 0.5110212373281687 5.866244325488287E-96 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 49 10 5151 45 4 false 0.5123260613615913 0.5123260613615913 0.0 system_development GO:0048731 12133 2686 49 16 3304 19 2 false 0.512597713489373 0.512597713489373 0.0 regulation_of_osteoblast_differentiation GO:0045667 12133 89 49 1 913 7 3 false 0.5134688227030315 0.5134688227030315 4.590259289121949E-126 organophosphate_catabolic_process GO:0046434 12133 1000 49 12 2495 29 2 false 0.5137006058343915 0.5137006058343915 0.0 positive_regulation_of_cAMP_biosynthetic_process GO:0030819 12133 69 49 1 134 1 5 false 0.5149253731343213 0.5149253731343213 7.0817799397690005E-40 endosome GO:0005768 12133 455 49 3 8213 49 2 false 0.515413800666572 0.515413800666572 0.0 protein-DNA_complex_assembly GO:0065004 12133 126 49 2 538 7 2 false 0.5158706563436039 0.5158706563436039 1.6410350721824938E-126 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 49 10 803 13 1 false 0.516135181089591 0.516135181089591 1.0286714317927864E-202 mRNA_export_from_nucleus GO:0006406 12133 60 49 1 116 1 2 false 0.5172413793103448 0.5172413793103448 1.7435958103584361E-34 regulation_of_cellular_carbohydrate_metabolic_process GO:0010675 12133 91 49 1 4058 32 3 false 0.5174070674707981 0.5174070674707981 1.6448652824301034E-188 regulation_of_carbohydrate_metabolic_process GO:0006109 12133 96 49 1 4268 32 2 false 0.5184190811040879 0.5184190811040879 9.169265262763212E-199 male_gonad_development GO:0008584 12133 84 49 1 162 1 2 false 0.5185185185184836 0.5185185185184836 3.0520910486495067E-48 epithelial_tube_morphogenesis GO:0060562 12133 245 49 2 340 2 2 false 0.5186534790907084 0.5186534790907084 6.979413529141176E-87 organelle_envelope GO:0031967 12133 629 49 4 7756 46 3 false 0.519039437106329 0.519039437106329 0.0 homeostasis_of_number_of_cells GO:0048872 12133 166 49 1 990 4 1 false 0.5206679836178234 0.5206679836178234 1.128853988781411E-193 leukocyte_migration GO:0050900 12133 224 49 2 1975 15 2 false 0.5210046239980479 0.5210046239980479 1.7898344026900835E-302 positive_regulation_of_cyclase_activity GO:0031281 12133 63 49 1 1064 12 3 false 0.5211481107632503 0.5211481107632503 2.5891490792503797E-103 dephosphorylation GO:0016311 12133 328 49 3 2776 23 1 false 0.5223425990822753 0.5223425990822753 0.0 cyclase_activity GO:0009975 12133 123 49 1 4901 29 1 false 0.5225234642001292 0.5225234642001292 7.077862449152851E-249 regulation_of_blood_pressure GO:0008217 12133 117 49 1 2120 13 2 false 0.5229663688815576 0.5229663688815576 6.820682324461924E-196 response_to_starvation GO:0042594 12133 104 49 1 2586 18 2 false 0.5235284504611867 0.5235284504611867 1.0260437683061592E-188 positive_regulation_of_apoptotic_process GO:0043065 12133 362 49 4 1377 14 3 false 0.5241311204890116 0.5241311204890116 0.0 dendrite GO:0030425 12133 276 49 2 534 3 1 false 0.5253188201654738 0.5253188201654738 6.975042602902724E-160 nucleoplasm_part GO:0044451 12133 805 49 9 2767 30 2 false 0.5254878857726156 0.5254878857726156 0.0 regulation_of_Ras_protein_signal_transduction GO:0046578 12133 270 49 5 417 7 2 false 0.526186870141658 0.526186870141658 7.174398789465976E-117 prostanoid_biosynthetic_process GO:0046457 12133 20 49 1 38 1 3 false 0.5263157894736858 0.5263157894736858 2.978140395000689E-11 response_to_ketone GO:1901654 12133 70 49 1 1822 19 2 false 0.5267517769925426 0.5267517769925426 2.649255790995827E-128 response_to_acid GO:0001101 12133 79 49 1 2369 22 1 false 0.527415674002459 0.527415674002459 8.553881899527543E-150 regulation_of_cell_growth GO:0001558 12133 243 49 3 1344 15 3 false 0.5275272510372653 0.5275272510372653 4.9010314548000585E-275 regulation_of_extrinsic_apoptotic_signaling_pathway GO:2001236 12133 43 49 1 138 2 2 false 0.5276631757113946 0.5276631757113946 9.021503775464772E-37 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 49 1 6380 35 3 false 0.5279011048842266 0.5279011048842266 2.5067679665083333E-283 mRNA_3'-UTR_binding GO:0003730 12133 20 49 1 91 3 1 false 0.5295303946989349 0.5295303946989349 1.5304206568397613E-20 nucleosome GO:0000786 12133 61 49 1 519 6 3 false 0.5295599776710647 0.5295599776710647 4.729950878459035E-81 positive_regulation_of_nucleotide_metabolic_process GO:0045981 12133 83 49 1 2578 23 4 false 0.5304418755395877 0.5304418755395877 1.0942419479084622E-158 regulation_of_nuclear_division GO:0051783 12133 100 49 1 712 5 2 false 0.5318813937193715 0.5318813937193715 7.811073934054147E-125 adherens_junction_assembly GO:0034333 12133 52 49 1 165 2 2 false 0.5322985957132393 0.5322985957132393 3.3179738133462556E-44 single-stranded_RNA_binding GO:0003727 12133 40 49 1 763 14 1 false 0.5325967094070094 0.5325967094070094 1.1547828689277465E-67 tight_junction_assembly GO:0070830 12133 31 49 1 58 1 2 false 0.5344827586206974 0.5344827586206974 3.809192954277456E-17 phosphorus-oxygen_lyase_activity GO:0016849 12133 123 49 1 230 1 1 false 0.5347826086956033 0.5347826086956033 1.920154677041111E-68 B_cell_homeostasis GO:0001782 12133 23 49 1 43 1 1 false 0.534883720930229 0.534883720930229 1.0410518840822442E-12 mesoderm_development GO:0007498 12133 92 49 1 1132 9 1 false 0.534998876229925 0.534998876229925 6.19400145712131E-138 chromosome_segregation GO:0007059 12133 136 49 1 7541 42 1 false 0.5353530966234878 0.5353530966234878 5.819868354628029E-295 tyrosine_phosphorylation_of_STAT_protein GO:0007260 12133 51 49 1 227 3 2 false 0.5357166062402183 0.5357166062402183 4.751307982054789E-52 negative_regulation_of_translation GO:0017148 12133 61 49 1 1470 18 4 false 0.535791703399944 0.535791703399944 1.1152524521517982E-109 phosphoric_diester_hydrolase_activity GO:0008081 12133 142 49 1 446 2 1 false 0.5358895550965578 0.5358895550965578 1.6123657849683337E-120 neuron_spine GO:0044309 12133 121 49 1 534 3 1 false 0.5381414463284787 0.5381414463284787 1.9159133440155296E-123 regulation_of_Rho_GTPase_activity GO:0032319 12133 95 49 2 233 4 2 false 0.5389350918431005 0.5389350918431005 7.3761210037366725E-68 cell-cell_junction_assembly GO:0007043 12133 58 49 1 181 2 2 false 0.5394106813995944 0.5394106813995944 7.851737058026464E-49 peptidyl-amino_acid_modification GO:0018193 12133 623 49 6 2370 22 1 false 0.5394185781355215 0.5394185781355215 0.0 cholesterol_efflux GO:0033344 12133 27 49 1 50 1 1 false 0.539999999999996 0.539999999999996 9.255552464864819E-15 development_of_primary_male_sexual_characteristics GO:0046546 12133 97 49 1 179 1 2 false 0.5418994413407667 0.5418994413407667 4.0970386268467766E-53 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 49 1 202 7 1 false 0.5419318356902139 0.5419318356902139 5.801734415928739E-29 DNA_packaging GO:0006323 12133 135 49 1 7668 44 3 false 0.5433177754551547 0.5433177754551547 3.2587442798347094E-294 lipase_activity GO:0016298 12133 187 49 1 814 3 1 false 0.5434893521481462 0.5434893521481462 8.941328372617339E-190 ceramide_metabolic_process GO:0006672 12133 37 49 1 68 1 1 false 0.5441176470588207 0.5441176470588207 4.563528183708786E-20 chromosome_organization GO:0051276 12133 689 49 4 2031 11 1 false 0.5445451882164594 0.5445451882164594 0.0 ubiquitin_ligase_complex GO:0000151 12133 147 49 1 9248 49 2 false 0.5448776113502685 0.5448776113502685 0.0 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 49 4 803 13 1 false 0.5452833563754103 0.5452833563754103 7.141936114023743E-209 microtubule_associated_complex GO:0005875 12133 110 49 1 3267 23 3 false 0.54636356089151 0.54636356089151 2.821671595839563E-208 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 49 6 2771 22 5 false 0.5479686984687043 0.5479686984687043 0.0 developmental_process_involved_in_reproduction GO:0003006 12133 340 49 3 3959 33 2 false 0.5482565515879906 0.5482565515879906 0.0 regulation_of_T_cell_activation GO:0050863 12133 186 49 1 339 1 2 false 0.548672566371674 0.548672566371674 1.0254523445533855E-100 regulation_of_cell_motility GO:2000145 12133 370 49 3 831 6 3 false 0.5491290470459627 0.5491290470459627 3.695619588048616E-247 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 49 19 3120 23 4 false 0.5492506554964492 0.5492506554964492 0.0 negative_regulation_of_cell_migration GO:0030336 12133 108 49 1 735 5 3 false 0.5493091966707726 0.5493091966707726 1.4353405807943923E-132 skeletal_system_development GO:0001501 12133 301 49 2 2686 16 1 false 0.5498076668741445 0.5498076668741445 0.0 macromolecular_complex_assembly GO:0065003 12133 973 49 13 1603 21 2 false 0.5502320904982521 0.5502320904982521 0.0 protein_kinase_binding GO:0019901 12133 341 49 5 384 5 1 false 0.550399032535713 0.550399032535713 5.20098898434574E-58 negative_regulation_of_neurogenesis GO:0050768 12133 81 49 1 956 9 3 false 0.5508120870652822 0.5508120870652822 7.263496623051508E-120 chromatin_assembly_or_disassembly GO:0006333 12133 126 49 1 539 3 1 false 0.5508992679146121 0.5508992679146121 1.2574164838803103E-126 DNA-dependent_transcription,_termination GO:0006353 12133 80 49 1 2751 27 2 false 0.5509667645348874 0.5509667645348874 1.5820458311792457E-156 regulation_of_receptor_activity GO:0010469 12133 89 49 1 3057 27 3 false 0.5512088800967551 0.5512088800967551 3.874143452259453E-174 single_organism_reproductive_process GO:0044702 12133 539 49 3 8107 43 2 false 0.5519108262145633 0.5519108262145633 0.0 regulatory_region_DNA_binding GO:0000975 12133 1169 49 7 2091 12 2 false 0.5526561741843292 0.5526561741843292 0.0 oogenesis GO:0048477 12133 36 49 1 65 1 1 false 0.5538461538461481 0.5538461538461481 3.9878950035701057E-19 negative_regulation_of_cellular_component_movement GO:0051271 12133 114 49 1 3032 21 3 false 0.5540385465268374 0.5540385465268374 2.6462769841807196E-210 cellular_response_to_extracellular_stimulus GO:0031668 12133 130 49 1 4577 28 4 false 0.5547937130148635 0.5547937130148635 5.475296256672863E-256 negative_regulation_of_ligase_activity GO:0051352 12133 71 49 1 1003 11 3 false 0.5559444452804049 0.5559444452804049 8.698138776450475E-111 cellular_response_to_hypoxia GO:0071456 12133 79 49 1 1210 12 3 false 0.5569413397492198 0.5569413397492198 3.484581288071841E-126 positive_regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900740 12133 24 49 1 43 1 3 false 0.558139534883719 0.558139534883719 1.2492622608986976E-12 anchoring_junction GO:0070161 12133 197 49 1 588 2 1 false 0.558199770538777 0.558199770538777 4.1212451424432254E-162 intracellular_transport_of_viral_material GO:0075733 12133 23 49 1 355 12 2 false 0.5582312590246705 0.5582312590246705 1.1844258992565298E-36 single-organism_carbohydrate_metabolic_process GO:0044723 12133 385 49 2 515 2 1 false 0.5584979789202698 0.5584979789202698 1.0653300741927565E-125 negative_regulation_of_NF-kappaB_import_into_nucleus GO:0042347 12133 17 49 1 51 2 3 false 0.5599999999999957 0.5599999999999957 6.76999067656327E-14 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 49 2 1663 22 2 false 0.5608745370806438 0.5608745370806438 7.181952736648417E-207 cyclic_purine_nucleotide_metabolic_process GO:0052652 12133 151 49 1 269 1 2 false 0.5613382899628113 0.5613382899628113 1.6379011785432358E-79 angiogenesis GO:0001525 12133 300 49 2 2776 17 3 false 0.5628526106271989 0.5628526106271989 0.0 cellular_cation_homeostasis GO:0030003 12133 289 49 1 513 1 2 false 0.5633528265106433 0.5633528265106433 6.525965777081911E-152 metal_ion_transport GO:0030001 12133 455 49 2 606 2 1 false 0.5634290701797242 0.5634290701797242 4.665536224038032E-147 regulation_of_protein_localization GO:0032880 12133 349 49 4 2148 24 2 false 0.5636244673551193 0.5636244673551193 0.0 regulation_of_lymphocyte_activation GO:0051249 12133 245 49 1 434 1 2 false 0.5645161290321338 0.5645161290321338 2.1869753110099554E-128 positive_regulation_of_endocytosis GO:0045807 12133 63 49 1 1023 13 4 false 0.5645369904662538 0.5645369904662538 3.3235317732048763E-102 calcium_ion_binding GO:0005509 12133 447 49 2 2699 11 1 false 0.5660141138860189 0.5660141138860189 0.0 cell_periphery GO:0071944 12133 2667 49 13 9983 49 1 false 0.5660909166700314 0.5660909166700314 0.0 cellular_response_to_interleukin-1 GO:0071347 12133 39 49 1 397 8 2 false 0.5661312713879894 0.5661312713879894 6.2361767471504674E-55 glucan_biosynthetic_process GO:0009250 12133 38 49 1 67 1 2 false 0.5671641791044822 0.5671641791044822 1.2679738523337074E-19 myeloid_cell_differentiation GO:0030099 12133 237 49 2 2177 17 2 false 0.5672524654801314 0.5672524654801314 0.0 negative_regulation_of_catabolic_process GO:0009895 12133 83 49 1 3124 31 3 false 0.5677936406736923 0.5677936406736923 1.0289413364876372E-165 positive_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090100 12133 57 49 1 918 13 3 false 0.5678643992445075 0.5678643992445075 3.1386577853752424E-92 regulation_of_cell_cycle_process GO:0010564 12133 382 49 3 1096 8 2 false 0.5691779323288817 0.5691779323288817 7.137372224746455E-307 polysome GO:0005844 12133 22 49 1 569 21 1 false 0.5697040254785257 0.5697040254785257 4.138788255326549E-40 induction_of_programmed_cell_death GO:0012502 12133 157 49 2 368 4 1 false 0.5708921289377847 0.5708921289377847 2.1106051638808005E-108 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 49 7 5447 44 3 false 0.571025596587694 0.571025596587694 0.0 protein_transporter_activity GO:0008565 12133 81 49 1 1579 16 2 false 0.5711768895668847 0.5711768895668847 3.989743647530564E-138 positive_regulation_of_purine_nucleotide_metabolic_process GO:1900544 12133 82 49 1 1209 12 3 false 0.5712195754045664 0.5712195754045664 1.376514335843937E-129 morphogenesis_of_a_branching_structure GO:0001763 12133 169 49 1 4284 21 3 false 0.5714014010976401 0.5714014010976401 2.023740855196032E-308 glomerular_visceral_epithelial_cell_development GO:0072015 12133 8 49 1 14 1 2 false 0.5714285714285714 0.5714285714285714 3.330003330003327E-4 NF-kappaB_import_into_nucleus GO:0042348 12133 34 49 1 220 5 2 false 0.5716604273220898 0.5716604273220898 9.912199511410154E-41 phosphoric_ester_hydrolase_activity GO:0042578 12133 446 49 2 814 3 1 false 0.5717350882131222 0.5717350882131222 1.3758870371320904E-242 regulation_of_angiogenesis GO:0045765 12133 127 49 1 665 4 3 false 0.572521880177929 0.572521880177929 3.739492527906887E-140 cardiovascular_system_development GO:0072358 12133 655 49 4 2686 16 2 false 0.5730675720622165 0.5730675720622165 0.0 circulatory_system_development GO:0072359 12133 655 49 4 2686 16 1 false 0.5730675720622165 0.5730675720622165 0.0 substrate-specific_transporter_activity GO:0022892 12133 620 49 3 746 3 1 false 0.5735915936445926 0.5735915936445926 1.886990037563331E-146 focal_adhesion_assembly GO:0048041 12133 45 49 1 130 2 2 false 0.5742397137745947 0.5742397137745947 5.211006355919991E-36 activation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0006919 12133 81 49 1 1375 14 3 false 0.5743715200981543 0.5743715200981543 4.023711257429167E-133 protein_complex_subunit_organization GO:0071822 12133 989 49 16 1256 20 1 false 0.5744267876553225 0.5744267876553225 2.2763776011987297E-281 apoptotic_mitochondrial_changes GO:0008637 12133 87 49 1 1476 14 2 false 0.5744655509537402 0.5744655509537402 5.447605955370739E-143 positive_regulation_of_ligase_activity GO:0051351 12133 84 49 1 1424 14 3 false 0.5748167577029543 0.5748167577029543 5.130084211911676E-138 germ_cell_development GO:0007281 12133 107 49 1 1560 12 4 false 0.5750555297189234 0.5750555297189234 1.0972879965646868E-168 positive_regulation_of_canonical_Wnt_receptor_signaling_pathway GO:0090263 12133 41 49 1 166 3 3 false 0.575575027382331 0.575575027382331 6.994942788129516E-40 induction_of_apoptosis GO:0006917 12133 156 49 2 363 4 2 false 0.5761649533199166 0.5761649533199166 4.583372865169243E-107 regulation_of_actin_cytoskeleton_organization GO:0032956 12133 166 49 1 476 2 3 false 0.576337903582687 0.576337903582687 5.437988564533384E-133 negative_regulation_of_MAPK_cascade GO:0043409 12133 99 49 2 537 10 3 false 0.5771485281983016 0.5771485281983016 7.769471694565091E-111 stem_cell_differentiation GO:0048863 12133 239 49 2 2154 17 1 false 0.5781884525428047 0.5781884525428047 0.0 transcription_coactivator_activity GO:0003713 12133 264 49 2 478 3 2 false 0.5783288763521566 0.5783288763521566 4.798051856605128E-142 phospholipase_C_activity GO:0004629 12133 107 49 1 185 1 2 false 0.5783783783783866 0.5783783783783866 3.369173077902444E-54 cellular_response_to_starvation GO:0009267 12133 87 49 1 1156 11 3 false 0.5787632256077081 0.5787632256077081 1.942511852273073E-133 intramolecular_oxidoreductase_activity GO:0016860 12133 43 49 1 123 2 1 false 0.5788351326136157 0.5788351326136157 3.559837991950172E-34 steroid_biosynthetic_process GO:0006694 12133 98 49 1 3573 31 3 false 0.5793001448611257 0.5793001448611257 2.291833143174281E-194 response_to_temperature_stimulus GO:0009266 12133 91 49 1 676 6 1 false 0.5814501835579939 0.5814501835579939 2.3046402907653703E-115 regulation_of_autophagy GO:0010506 12133 56 49 1 546 8 2 false 0.5817294651415651 0.5817294651415651 6.882802628685981E-78 vesicle-mediated_transport GO:0016192 12133 895 49 8 2783 25 1 false 0.5819950220996196 0.5819950220996196 0.0 spliceosomal_snRNP_assembly GO:0000387 12133 30 49 1 259 7 2 false 0.5821185930396944 0.5821185930396944 6.073894661120439E-40 nuclear_chromosome GO:0000228 12133 278 49 3 2899 31 3 false 0.5829155844859781 0.5829155844859781 0.0 regulation_of_phospholipase_activity GO:0010517 12133 105 49 1 180 1 2 false 0.5833333333333213 0.5833333333333213 1.3354430203572309E-52 positive_regulation_of_protein_kinase_B_signaling_cascade GO:0051897 12133 58 49 1 495 7 3 false 0.5844098699359429 0.5844098699359429 3.926574524631079E-77 ligase_activity GO:0016874 12133 504 49 3 4901 29 1 false 0.5854913228578446 0.5854913228578446 0.0 DNA_catabolic_process GO:0006308 12133 66 49 1 2145 28 3 false 0.585513418417536 0.585513418417536 1.9973602853494904E-127 synaptic_transmission GO:0007268 12133 515 49 2 923 3 2 false 0.5866484319796914 0.5866484319796914 2.6714189194289816E-274 cellular_response_to_inorganic_substance GO:0071241 12133 73 49 1 1690 20 2 false 0.5886187000784311 0.5886187000784311 5.009564075302306E-130 negative_regulation_of_cell_motility GO:2000146 12133 110 49 1 800 6 4 false 0.5895596968628678 0.5895596968628678 1.883997981968334E-138 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 49 4 1393 15 3 false 0.5896048568536336 0.5896048568536336 0.0 toll-like_receptor_signaling_pathway GO:0002224 12133 129 49 4 147 4 1 false 0.5896214319454524 0.5896214319454524 1.843896992838607E-23 transcription-coupled_nucleotide-excision_repair GO:0006283 12133 46 49 1 78 1 1 false 0.589743589743583 0.589743589743583 1.2785885050503116E-22 endothelial_cell_migration GO:0043542 12133 100 49 2 130 2 1 false 0.5903398926654729 0.5903398926654729 3.8279880512589226E-30 Ras_GTPase_activator_activity GO:0005099 12133 87 49 1 339 3 3 false 0.5904867373174395 0.5904867373174395 2.872872762914377E-83 protein_modification_by_small_protein_removal GO:0070646 12133 77 49 1 645 7 1 false 0.5911258602827024 0.5911258602827024 7.565398504158586E-102 amino_acid_binding GO:0016597 12133 110 49 1 186 1 1 false 0.5913978494623976 0.5913978494623976 3.905422178213833E-54 cellular_macromolecular_complex_assembly GO:0034622 12133 517 49 7 973 13 1 false 0.591767689366377 0.591767689366377 3.312522477266262E-291 regulation_of_tyrosine_phosphorylation_of_Stat3_protein GO:0042516 12133 29 49 1 49 1 2 false 0.591836734693884 0.591836734693884 3.536377094612393E-14 positive_regulation_of_lipase_activity GO:0060193 12133 104 49 1 632 5 3 false 0.5942826350901387 0.5942826350901387 4.344193956592552E-122 regulation_of_histone_modification GO:0031056 12133 77 49 1 1240 14 3 false 0.5944108781430092 0.5944108781430092 1.0351200557646026E-124 RNA_stabilization GO:0043489 12133 22 49 1 37 1 1 false 0.5945945945945961 0.5945945945945961 1.0678969112465738E-10 regulation_of_chromosome_organization GO:0033044 12133 114 49 1 1070 8 2 false 0.595208893451874 0.595208893451874 5.856752364330647E-157 glycosylation GO:0070085 12133 140 49 1 385 2 1 false 0.5956439393939456 0.5956439393939456 5.964220032896676E-109 localization_of_cell GO:0051674 12133 785 49 6 3467 27 1 false 0.5958639643341909 0.5958639643341909 0.0 DNA_methylation_or_demethylation GO:0044728 12133 48 49 2 62 2 1 false 0.596509783183519 0.596509783183519 3.438909653668478E-14 basal_transcription_machinery_binding GO:0001098 12133 464 49 3 6397 42 1 false 0.5965722430993515 0.5965722430993515 0.0 cellular_response_to_nitrogen_compound GO:1901699 12133 347 49 4 1721 20 2 false 0.5966739283322113 0.5966739283322113 0.0 nucleosome_organization GO:0034728 12133 115 49 1 566 4 2 false 0.5979676200883093 0.5979676200883093 1.9962820173380563E-123 negative_regulation_of_locomotion GO:0040013 12133 129 49 1 3189 22 3 false 0.5980799811471212 0.5980799811471212 7.329512152442089E-234 gonad_development GO:0008406 12133 150 49 1 2876 17 4 false 0.5987694712264228 0.5987694712264228 4.529833702866928E-255 regulation_of_androgen_receptor_signaling_pathway GO:0060765 12133 21 49 1 81 3 2 false 0.5989217065166448 0.5989217065166448 7.333410898212426E-20 lamellipodium GO:0030027 12133 121 49 1 990 7 2 false 0.5996836673011983 0.5996836673011983 5.739208350847419E-159 regulation_of_glycogen_biosynthetic_process GO:0005979 12133 24 49 1 40 1 3 false 0.6000000000000054 0.6000000000000054 1.59103669367912E-11 cellular_response_to_lipid GO:0071396 12133 242 49 3 1527 19 2 false 0.6001686843556173 0.6001686843556173 4.5218037632292525E-289 positive_regulation_of_cell_adhesion GO:0045785 12133 114 49 1 3174 25 3 false 0.6006761264175686 0.6006761264175686 1.3009596629773978E-212 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 49 42 7976 46 2 false 0.6012945905619216 0.6012945905619216 0.0 cellular_response_to_abiotic_stimulus GO:0071214 12133 140 49 1 4330 28 2 false 0.602754229062687 0.602754229062687 1.0171050636125265E-267 response_to_molecule_of_bacterial_origin GO:0002237 12133 194 49 2 1960 20 3 false 0.6037044895799482 0.6037044895799482 5.221043387884517E-274 generation_of_neurons GO:0048699 12133 883 49 8 940 8 1 false 0.6050943601555309 0.6050943601555309 7.799501535546468E-93 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 49 6 1804 20 2 false 0.6050971568627194 0.6050971568627194 0.0 regulation_of_focal_adhesion_assembly GO:0051893 12133 27 49 1 73 2 3 false 0.6061643835616477 0.6061643835616477 1.3403979125160586E-20 plasma_membrane GO:0005886 12133 2594 49 12 10252 49 3 false 0.606547278641689 0.606547278641689 0.0 response_to_nitrogen_compound GO:1901698 12133 552 49 5 2369 22 1 false 0.6081001021121366 0.6081001021121366 0.0 transferase_activity,_transferring_hexosyl_groups GO:0016758 12133 73 49 1 120 1 1 false 0.608333333333335 0.608333333333335 1.7281938068391106E-34 anatomical_structure_morphogenesis GO:0009653 12133 1664 49 10 3447 21 2 false 0.6086549432440227 0.6086549432440227 0.0 proteolysis GO:0006508 12133 732 49 7 3431 34 1 false 0.6101476288739534 0.6101476288739534 0.0 cellular_response_to_topologically_incorrect_protein GO:0035967 12133 87 49 1 2172 23 3 false 0.6113688317315178 0.6113688317315178 5.95891199322288E-158 response_to_bacterium GO:0009617 12133 273 49 2 475 3 1 false 0.6115022402260493 0.6115022402260493 5.69705453618735E-140 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 49 1 147 1 1 false 0.6122448979591654 0.6122448979591654 3.485982605742994E-42 cell-cell_junction GO:0005911 12133 222 49 1 588 2 1 false 0.6129576191637892 0.6129576191637892 1.5852162200644845E-168 positive_regulation_of_phospholipase_activity GO:0010518 12133 100 49 1 163 1 3 false 0.613496932515323 0.613496932515323 9.231150730946075E-47 establishment_of_cell_polarity GO:0030010 12133 64 49 1 104 1 1 false 0.615384615384606 0.615384615384606 1.0052317592714408E-29 small_conjugating_protein-specific_protease_activity GO:0019783 12133 51 49 1 295 5 1 false 0.6156499490065142 0.6156499490065142 1.675313493425089E-58 response_to_oxygen_levels GO:0070482 12133 214 49 2 676 6 1 false 0.6157972717151244 0.6157972717151244 1.6255941364061853E-182 nucleotide-excision_repair GO:0006289 12133 78 49 1 368 4 1 false 0.6160431744652615 0.6160431744652615 5.504322769590107E-82 response_to_topologically_incorrect_protein GO:0035966 12133 133 49 1 3273 23 2 false 0.6161202925454865 0.6161202925454865 7.334457285081863E-241 regulation_of_NF-kappaB_import_into_nucleus GO:0042345 12133 34 49 1 197 5 3 false 0.6163549013523795 0.6163549013523795 5.91301474468331E-39 protein_folding GO:0006457 12133 183 49 2 3038 34 1 false 0.6169571295449607 0.6169571295449607 1.582632936584301E-299 histone_deacetylase_binding GO:0042826 12133 62 49 1 1005 15 1 false 0.6179050864140622 0.6179050864140622 1.577479125629217E-100 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 49 1 207 2 2 false 0.6187796069602799 0.6187796069602799 2.976076769798144E-59 cation_homeostasis GO:0055080 12133 330 49 1 532 1 1 false 0.6203007518797987 0.6203007518797987 1.1320770482912473E-152 enteroendocrine_cell_differentiation GO:0035883 12133 18 49 1 29 1 1 false 0.6206896551724117 0.6206896551724117 2.890399797209533E-8 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 49 7 3631 35 4 false 0.6208683337410252 0.6208683337410252 0.0 negative_regulation_of_canonical_Wnt_receptor_signaling_pathway GO:0090090 12133 66 49 1 172 2 3 false 0.621583027335766 0.621583027335766 2.9232002422047036E-49 vascular_process_in_circulatory_system GO:0003018 12133 118 49 1 307 2 1 false 0.6217666219580926 0.6217666219580926 3.250495259622763E-88 response_to_type_I_interferon GO:0034340 12133 60 49 1 900 14 2 false 0.6221273732056791 0.6221273732056791 3.4610416117449214E-95 dendrite_morphogenesis GO:0048813 12133 66 49 1 511 7 3 false 0.6225127063439624 0.6225127063439624 7.698657029517716E-85 positive_regulation_of_endothelial_cell_migration GO:0010595 12133 45 49 1 117 2 3 false 0.6233421750663073 0.6233421750663073 1.8451178464107226E-33 cyclin-dependent_protein_kinase_activity GO:0097472 12133 105 49 1 1997 18 2 false 0.623367774363498 0.623367774363498 5.046200754373572E-178 regulation_of_programmed_cell_death GO:0043067 12133 1031 49 11 1410 15 2 false 0.6234199483380368 0.6234199483380368 0.0 regulation_of_ion_transport GO:0043269 12133 307 49 2 1393 9 2 false 0.6236895265241287 0.6236895265241287 3.368915E-318 cellular_response_to_organic_nitrogen GO:0071417 12133 323 49 4 1478 19 4 false 0.6239221065357058 0.6239221065357058 0.0 regulation_of_ligase_activity GO:0051340 12133 98 49 1 2061 20 2 false 0.6243059160893205 0.6243059160893205 1.6310105681359867E-170 cellular_response_to_unfolded_protein GO:0034620 12133 82 49 1 131 1 2 false 0.6259541984732812 0.6259541984732812 3.4132414427749756E-37 regulation_of_cell-substrate_junction_assembly GO:0090109 12133 27 49 1 70 2 2 false 0.6260869565217374 0.6260869565217374 5.491922830490753E-20 membrane-bounded_organelle GO:0043227 12133 7284 49 42 7980 46 1 false 0.6265570982939255 0.6265570982939255 0.0 tyrosine_phosphorylation_of_Stat3_protein GO:0042503 12133 32 49 1 51 1 1 false 0.6274509803921535 0.6274509803921535 2.0635800457973343E-14 negative_regulation_of_kinase_activity GO:0033673 12133 172 49 2 1181 14 3 false 0.6276460953970918 0.6276460953970918 3.9159843646516213E-212 nuclear_transport GO:0051169 12133 331 49 5 1148 18 1 false 0.628353482724116 0.628353482724116 1.3196682196913852E-298 negative_regulation_of_organelle_organization GO:0010639 12133 168 49 1 2125 12 3 false 0.6287893947917216 0.6287893947917216 2.2467097914760192E-254 cell-substrate_junction_assembly GO:0007044 12133 62 49 1 159 2 1 false 0.6293288750895543 0.6293288750895543 1.0273123292116476E-45 osteoblast_differentiation GO:0001649 12133 126 49 1 2191 17 2 false 0.6360287297098639 0.6360287297098639 1.111366645898294E-208 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 49 26 5532 47 4 false 0.6371722230509499 0.6371722230509499 0.0 apical_junction_assembly GO:0043297 12133 37 49 1 58 1 1 false 0.6379310344827669 0.6379310344827669 2.991639077401756E-16 positive_regulation_of_DNA_metabolic_process GO:0051054 12133 92 49 1 2322 25 4 false 0.6379783292938042 0.6379783292938042 1.6937907011714837E-167 cell_morphogenesis GO:0000902 12133 766 49 8 810 8 1 false 0.6383842231108815 0.6383842231108815 9.285456073507826E-74 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 49 2 1130 13 2 false 0.6385344408728197 0.6385344408728197 1.9819409219356823E-214 multicellular_organism_reproduction GO:0032504 12133 482 49 3 4643 31 2 false 0.6385552335961837 0.6385552335961837 0.0 transport GO:0006810 12133 2783 49 25 2833 25 1 false 0.6394913861456424 0.6394913861456424 1.147202604491021E-108 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 49 1 2180 19 2 false 0.6411508638640603 0.6411508638640603 1.341003616993524E-193 peptidyl-lysine_acetylation GO:0018394 12133 127 49 1 198 1 2 false 0.6414141414141271 0.6414141414141271 1.293028032371008E-55 glycogen_metabolic_process GO:0005977 12133 58 49 1 145 2 2 false 0.6416666666666049 0.6416666666666049 6.156136085146564E-42 organic_hydroxy_compound_transport GO:0015850 12133 103 49 1 2569 25 2 false 0.6422397719831734 0.6422397719831734 4.89938384254503E-187 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 49 7 5032 44 4 false 0.642483262481319 0.642483262481319 0.0 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 49 7 3453 31 4 false 0.6427192985819058 0.6427192985819058 0.0 mitochondrial_envelope GO:0005740 12133 378 49 2 803 4 2 false 0.6427771696734769 0.6427771696734769 2.632819629334664E-240 organelle_organization GO:0006996 12133 2031 49 11 7663 44 2 false 0.6459511330739413 0.6459511330739413 0.0 tube_development GO:0035295 12133 371 49 2 3304 19 2 false 0.6467280781193331 0.6467280781193331 0.0 development_of_primary_sexual_characteristics GO:0045137 12133 174 49 1 3105 18 3 false 0.6468977431812297 0.6468977431812297 2.1612319791507408E-290 inactivation_of_MAPK_activity GO:0000188 12133 25 49 1 62 2 1 false 0.6478053939714584 0.6478053939714584 6.784005293429779E-18 regulation_of_peptide_transport GO:0090087 12133 133 49 1 962 7 2 false 0.648336106118831 0.648336106118831 3.702869511284133E-167 morphogenesis_of_an_epithelium GO:0002009 12133 328 49 2 691 4 2 false 0.6490672720816876 0.6490672720816876 7.776670515222191E-207 cytoplasmic_vesicle GO:0031410 12133 764 49 4 8540 49 3 false 0.6497607804304952 0.6497607804304952 0.0 transferase_activity,_transferring_glycosyl_groups GO:0016757 12133 120 49 1 1779 15 1 false 0.6507053239345516 0.6507053239345516 3.8700015520954533E-190 kinase_regulator_activity GO:0019207 12133 125 49 1 1851 15 3 false 0.651083341663661 0.651083341663661 5.123060762627793E-198 carbohydrate_biosynthetic_process GO:0016051 12133 132 49 1 4212 33 2 false 0.6517438329659233 0.6517438329659233 3.288354819591378E-254 regulation_of_ERK1_and_ERK2_cascade GO:0070372 12133 101 49 2 439 9 2 false 0.6518035708713739 0.6518035708713739 3.260158634829054E-102 regulation_of_nucleotide_biosynthetic_process GO:0030808 12133 146 49 1 3406 24 3 false 0.6518491960877608 0.6518491960877608 5.390613252169377E-261 cellular_response_to_oxygen_levels GO:0071453 12133 85 49 1 1663 20 2 false 0.6519828901811663 0.6519828901811663 4.192529980934564E-145 cell-substrate_adherens_junction_assembly GO:0007045 12133 45 49 1 69 1 2 false 0.6521739130434739 0.6521739130434739 4.3372108507464655E-19 regulation_of_cyclin-dependent_protein_serine/threonine_kinase_activity GO:0000079 12133 77 49 1 918 12 3 false 0.6528191337473981 0.6528191337473981 2.8017058584530626E-114 regulation_of_reproductive_process GO:2000241 12133 171 49 1 6891 42 2 false 0.6530486931561461 0.6530486931561461 0.0 positive_regulation_of_growth GO:0045927 12133 130 49 1 3267 26 3 false 0.6535025567983521 0.6535025567983521 1.2617745932569076E-236 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 49 7 3780 33 4 false 0.6535120075573037 0.6535120075573037 0.0 regulation_of_vasculature_development GO:1901342 12133 141 49 1 1139 8 2 false 0.6537904501454375 0.6537904501454375 1.7255097841170828E-184 syncytium_formation_by_plasma_membrane_fusion GO:0000768 12133 19 49 1 29 1 2 false 0.6551724137931041 0.6551724137931041 4.992508740634664E-8 glycogen_biosynthetic_process GO:0005978 12133 38 49 1 58 1 2 false 0.6551724137931088 0.6551724137931088 5.413442140060302E-16 translation_elongation_factor_activity GO:0003746 12133 22 49 1 180 8 2 false 0.6553479626331454 0.6553479626331454 1.0368938565383413E-28 Notch_signaling_pathway GO:0007219 12133 113 49 1 1975 18 1 false 0.6553549107313855 0.6553549107313855 2.33429872590278E-187 chromatin_assembly GO:0031497 12133 105 49 1 1438 14 3 false 0.6557938229279443 0.6557938229279443 1.4446222867318886E-162 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 49 7 4429 36 3 false 0.6559457167581434 0.6559457167581434 0.0 positive_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043280 12133 101 49 1 1376 14 3 false 0.6578679748565819 0.6578679748565819 4.055423334241229E-156 regulation_of_actin_filament-based_process GO:0032970 12133 192 49 1 6365 35 2 false 0.6586829063134061 0.6586829063134061 0.0 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 49 1 759 8 3 false 0.6587270243640193 0.6587270243640193 1.1458874617943115E-123 regulation_of_Ras_GTPase_activity GO:0032318 12133 179 49 3 357 6 2 false 0.6602150815239478 0.6602150815239478 8.083441090582102E-107 biological_adhesion GO:0022610 12133 714 49 3 10446 49 1 false 0.6603842541816537 0.6603842541816537 0.0 single-multicellular_organism_process GO:0044707 12133 4095 49 21 8057 43 2 false 0.6607169459137843 0.6607169459137843 0.0 positive_regulation_of_GTPase_activity GO:0043547 12133 241 49 2 923 8 3 false 0.6610416642859963 0.6610416642859963 2.240962289646545E-229 zinc_ion_binding GO:0008270 12133 1314 49 4 1457 4 1 false 0.6612235173177182 0.6612235173177182 2.194714234876188E-202 cell_cortex GO:0005938 12133 175 49 1 6402 39 2 false 0.6618213519090521 0.6618213519090521 0.0 anterior/posterior_pattern_specification GO:0009952 12133 163 49 1 246 1 1 false 0.6626016260162862 0.6626016260162862 9.328053240584328E-68 cytoplasmic_vesicle_membrane GO:0030659 12133 302 49 1 719 2 3 false 0.6639715482278123 0.6639715482278123 1.2351303462379864E-211 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 49 2 1631 17 2 false 0.6641789348541638 0.6641789348541638 3.3133814045702313E-271 ERK1_and_ERK2_cascade GO:0070371 12133 118 49 2 502 9 1 false 0.6646319923832538 0.6646319923832538 3.0844274691588307E-118 cell-substrate_adherens_junction GO:0005924 12133 125 49 1 188 1 2 false 0.6648936170212674 0.6648936170212674 1.3846447149399673E-51 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 49 1 1813 15 1 false 0.6650412511830434 0.6650412511830434 4.219154160176784E-199 negative_regulation_of_protein_kinase_activity GO:0006469 12133 163 49 2 1050 14 4 false 0.6650932460602628 0.6650932460602628 4.119509868513009E-196 embryo_development GO:0009790 12133 768 49 4 3347 19 3 false 0.665672875636468 0.665672875636468 0.0 response_to_wounding GO:0009611 12133 905 49 6 2540 18 1 false 0.6663581401294291 0.6663581401294291 0.0 mRNA_stabilization GO:0048255 12133 22 49 1 33 1 2 false 0.6666666666666647 0.6666666666666647 5.166978132108427E-9 PML_body_organization GO:0030578 12133 4 49 1 6 1 1 false 0.6666666666666662 0.6666666666666662 0.06666666666666664 neurotrophin_TRK_receptor_binding GO:0005167 12133 6 49 1 9 1 1 false 0.6666666666666665 0.6666666666666665 0.011904761904761887 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 49 2 217 3 2 false 0.667225139618147 0.667225139618147 2.2668758893633536E-62 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 49 1 695 9 3 false 0.669584165066607 0.669584165066607 3.5521820546065696E-107 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 49 2 522 9 3 false 0.6709793556213086 0.6709793556213086 1.2617392241842968E-123 ribosome_biogenesis GO:0042254 12133 144 49 3 243 5 1 false 0.671036189309024 0.671036189309024 8.984879194471426E-71 response_to_mechanical_stimulus GO:0009612 12133 123 49 1 1395 12 2 false 0.6711813511233571 0.6711813511233571 5.1192974954704945E-180 positive_regulation_of_peptidase_activity GO:0010952 12133 121 49 1 1041 9 3 false 0.6726238453490432 0.6726238453490432 8.90382030646545E-162 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 49 7 4298 36 4 false 0.6727221869170212 0.6727221869170212 0.0 blood_vessel_morphogenesis GO:0048514 12133 368 49 2 2812 17 3 false 0.6728438114000858 0.6728438114000858 0.0 phosphoprotein_phosphatase_activity GO:0004721 12133 206 49 1 306 1 1 false 0.6732026143789835 0.6732026143789835 2.1851087098036358E-83 establishment_of_RNA_localization GO:0051236 12133 124 49 1 2839 25 2 false 0.6741613370010215 0.6741613370010215 1.4765023034812589E-220 nuclear_envelope GO:0005635 12133 258 49 2 3962 35 3 false 0.6756267787552988 0.6756267787552988 0.0 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 49 2 929 7 2 false 0.6767246262161694 0.6767246262161694 1.7613668775256747E-246 ER_to_Golgi_vesicle-mediated_transport GO:0006888 12133 53 49 1 735 15 2 false 0.6782139753715921 0.6782139753715921 3.564785772570493E-82 negative_regulation_of_Wnt_receptor_signaling_pathway GO:0030178 12133 93 49 1 705 8 3 false 0.6794785051299509 0.6794785051299509 8.718998498418959E-119 cellular_membrane_fusion GO:0006944 12133 93 49 1 786 9 2 false 0.6800323440159295 0.6800323440159295 1.7836379235146202E-123 regulation_of_anatomical_structure_morphogenesis GO:0022603 12133 528 49 3 2074 13 2 false 0.6818123528011824 0.6818123528011824 0.0 positive_regulation_of_nucleocytoplasmic_transport GO:0046824 12133 75 49 1 367 5 3 false 0.6833961832805786 0.6833961832805786 3.7707577442500014E-80 apoptotic_DNA_fragmentation GO:0006309 12133 26 49 1 38 1 2 false 0.6842105263157929 0.6842105263157929 3.6934780388979485E-10 mitotic_cell_cycle GO:0000278 12133 625 49 5 1295 11 1 false 0.6858512291804721 0.6858512291804721 0.0 response_to_organic_nitrogen GO:0010243 12133 519 49 5 1787 19 3 false 0.6874257102134091 0.6874257102134091 0.0 fatty_acid_metabolic_process GO:0006631 12133 214 49 1 666 3 2 false 0.6880654093717447 0.6880654093717447 7.544095427296943E-181 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 49 9 4582 38 3 false 0.6884480486988936 0.6884480486988936 0.0 double-strand_break_repair_via_homologous_recombination GO:0000724 12133 48 49 1 109 2 2 false 0.6890927624872707 0.6890927624872707 4.364037891784993E-32 DNA_conformation_change GO:0071103 12133 194 49 2 791 9 1 false 0.6896332248569956 0.6896332248569956 1.3022788504353465E-190 regulation_of_JAK-STAT_cascade GO:0046425 12133 66 49 1 656 11 2 false 0.6914608938047481 0.6914608938047481 1.950107224419378E-92 membrane_fusion GO:0061025 12133 96 49 1 787 9 1 false 0.6918597569920519 0.6918597569920519 4.051495195188967E-126 mRNA_3'-end_processing GO:0031124 12133 86 49 2 386 10 2 false 0.6925817247981638 0.6925817247981638 2.4694341980396157E-88 transporter_activity GO:0005215 12133 746 49 3 10383 49 2 false 0.6939670594429631 0.6939670594429631 0.0 cellular_response_to_type_I_interferon GO:0071357 12133 59 49 1 382 7 2 false 0.694114894836959 0.694114894836959 7.131731716015008E-71 RNA_3'-end_processing GO:0031123 12133 98 49 2 601 14 1 false 0.6948829471312459 0.6948829471312459 1.9130441150898719E-115 DNA_replication GO:0006260 12133 257 49 2 3702 34 3 false 0.6950545069514542 0.6950545069514542 0.0 negative_regulation_of_apoptotic_process GO:0043066 12133 537 49 5 1377 14 3 false 0.6952837373491874 0.6952837373491874 0.0 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 49 9 181 9 1 false 0.695418000696852 0.695418000696852 8.905994863592909E-13 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 49 1 254 3 3 false 0.696626977951671 0.696626977951671 3.7262148804586973E-69 protein-DNA_complex_subunit_organization GO:0071824 12133 147 49 2 1256 20 1 false 0.6994539310196161 0.6994539310196161 3.54580927907897E-196 regulation_of_multi-organism_process GO:0043900 12133 193 49 1 6817 42 2 false 0.7017843443451978 0.7017843443451978 0.0 generation_of_precursor_metabolites_and_energy GO:0006091 12133 364 49 2 7256 48 1 false 0.7021082510147217 0.7021082510147217 0.0 cell_projection_part GO:0044463 12133 491 49 2 9983 49 2 false 0.7021423468872898 0.7021423468872898 0.0 protein_modification_process GO:0036211 12133 2370 49 22 3518 34 2 false 0.7022906288476902 0.7022906288476902 0.0 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 49 1 361 3 1 false 0.7037065615217533 0.7037065615217533 4.560830022372086E-99 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 49 11 2517 29 2 false 0.7040595207780092 0.7040595207780092 0.0 cell-cell_junction_organization GO:0045216 12133 152 49 2 181 2 1 false 0.704481276857021 0.704481276857021 3.1886200066761254E-34 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 49 9 4456 38 4 false 0.7046538636435343 0.7046538636435343 0.0 cellular_carbohydrate_metabolic_process GO:0044262 12133 183 49 1 7315 48 2 false 0.7047905580237843 0.7047905580237843 0.0 regulation_of_lyase_activity GO:0051339 12133 117 49 1 1793 18 2 false 0.70495896261402 0.70495896261402 4.0773224530305873E-187 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 49 7 106 7 2 false 0.7057679667186002 0.7057679667186002 9.867686559172291E-9 type_B_pancreatic_cell_development GO:0003323 12133 12 49 1 17 1 2 false 0.705882352941178 0.705882352941178 1.6160310277957323E-4 negative_regulation_of_phosphorylation GO:0042326 12133 215 49 2 1463 16 3 false 0.7062536233982488 0.7062536233982488 2.1310280163327356E-264 microtubule_binding GO:0008017 12133 106 49 1 150 1 1 false 0.706666666666671 0.706666666666671 5.3333104558304893E-39 mitochondrion_organization GO:0007005 12133 215 49 1 2031 11 1 false 0.7088829521991253 0.7088829521991253 4.082912305313268E-297 regulation_of_endocytosis GO:0030100 12133 113 49 1 1437 15 3 false 0.709101996091283 0.709101996091283 3.3139638850760945E-171 macroautophagy GO:0016236 12133 49 49 1 146 3 2 false 0.7098094788222307 0.7098094788222307 4.979783011193841E-40 cell_division GO:0051301 12133 438 49 2 7541 42 1 false 0.7100200389388711 0.7100200389388711 0.0 sensory_perception GO:0007600 12133 302 49 1 894 3 1 false 0.7101272656643685 0.7101272656643685 1.7003226454977518E-247 adenylate_cyclase_activity GO:0004016 12133 103 49 1 145 1 3 false 0.710344827586197 0.710344827586197 1.7288474062512548E-37 type_I_interferon-mediated_signaling_pathway GO:0060337 12133 59 49 1 318 6 2 false 0.7112590031421937 0.7112590031421937 9.855417365479732E-66 tissue_homeostasis GO:0001894 12133 93 49 1 201 2 2 false 0.7125373134327752 0.7125373134327752 9.66633233825566E-60 U12-type_spliceosomal_complex GO:0005689 12133 24 49 1 150 7 1 false 0.7129259911610224 0.7129259911610224 2.5760759444825708E-28 blood_vessel_development GO:0001568 12133 420 49 2 3152 18 3 false 0.7136752249135716 0.7136752249135716 0.0 protein_localization_to_microtubule_cytoskeleton GO:0072698 12133 5 49 1 7 1 1 false 0.7142857142857142 0.7142857142857142 0.047619047619047596 T_cell_activation GO:0042110 12133 288 49 1 403 1 1 false 0.7146401985111832 0.7146401985111832 5.060432780788644E-104 cellular_chemical_homeostasis GO:0055082 12133 525 49 1 734 1 2 false 0.7152588555855657 0.7152588555855657 1.1478565010718528E-189 cellular_lipid_catabolic_process GO:0044242 12133 105 49 1 2404 28 3 false 0.7156960805743233 0.7156960805743233 1.0885633436927589E-186 maintenance_of_protein_location GO:0045185 12133 100 49 1 1490 18 2 false 0.715764046913331 0.715764046913331 1.3409119998512189E-158 tissue_morphogenesis GO:0048729 12133 415 49 2 2931 17 3 false 0.7170138682127124 0.7170138682127124 0.0 vacuolar_part GO:0044437 12133 186 49 1 7185 48 3 false 0.7172370276659876 0.7172370276659876 0.0 macromolecule_glycosylation GO:0043413 12133 137 49 1 2464 22 2 false 0.7175032610164378 0.7175032610164378 5.229995253563594E-229 regulation_of_homeostatic_process GO:0032844 12133 239 49 1 6742 35 2 false 0.718186585695962 0.718186585695962 0.0 regulation_of_cyclase_activity GO:0031279 12133 115 49 1 1700 18 2 false 0.7184276840797641 0.7184276840797641 4.764508019192963E-182 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 49 3 673 6 2 false 0.7226718913326854 0.7226718913326854 4.9348138289436974E-201 vesicle GO:0031982 12133 834 49 4 7980 46 1 false 0.722752708573587 0.722752708573587 0.0 DNA_repair GO:0006281 12133 368 49 4 977 12 2 false 0.7230787477867916 0.7230787477867916 3.284245924949814E-280 enzyme_regulator_activity GO:0030234 12133 771 49 3 10257 49 3 false 0.7235775486992192 0.7235775486992192 0.0 endomembrane_system GO:0012505 12133 1211 49 5 9983 49 1 false 0.725161919984015 0.725161919984015 0.0 nuclear_hormone_receptor_binding GO:0035257 12133 104 49 2 122 2 1 false 0.7256469313101672 0.7256469313101672 6.677251530520905E-22 regulation_of_nucleocytoplasmic_transport GO:0046822 12133 147 49 2 450 7 2 false 0.7261920419127679 0.7261920419127679 8.40005869125793E-123 morphogenesis_of_a_branching_epithelium GO:0061138 12133 160 49 1 336 2 2 false 0.7263681592040939 0.7263681592040939 2.40154258695507E-100 cell_proliferation GO:0008283 12133 1316 49 6 8052 43 1 false 0.7264958613350444 0.7264958613350444 0.0 protein_glycosylation GO:0006486 12133 137 49 1 2394 22 3 false 0.7281035028763321 0.7281035028763321 3.0420045355065773E-227 mitochondrial_transport GO:0006839 12133 124 49 1 2454 25 2 false 0.728237768275049 0.728237768275049 1.607876790046367E-212 monovalent_inorganic_cation_transmembrane_transporter_activity GO:0015077 12133 198 49 1 413 2 2 false 0.7296010719577959 0.7296010719577959 1.708187099767858E-123 lipid_metabolic_process GO:0006629 12133 769 49 4 7599 48 3 false 0.7299296696483959 0.7299296696483959 0.0 Cajal_body GO:0015030 12133 46 49 1 272 7 1 false 0.7309519575702558 0.7309519575702558 3.189172863463676E-53 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 49 7 307 11 1 false 0.7328460029543132 0.7328460029543132 1.4733469150792184E-83 ubiquitin_binding GO:0043130 12133 61 49 2 71 2 1 false 0.7364185110663888 0.7364185110663888 2.1657301017057942E-12 negative_regulation_of_protein_phosphorylation GO:0001933 12133 204 49 2 1311 16 4 false 0.7380642459493979 0.7380642459493979 2.3779440904857207E-245 cellular_response_to_metal_ion GO:0071248 12133 69 49 1 192 3 2 false 0.7394073780656771 0.7394073780656771 5.854997654482861E-54 positive_regulation_of_endopeptidase_activity GO:0010950 12133 112 49 1 476 5 3 false 0.7401969540304025 0.7401969540304025 3.786215967470695E-112 kinase_binding GO:0019900 12133 384 49 5 1005 15 1 false 0.7403940304985992 0.7403940304985992 2.0091697589355545E-289 microtubule_organizing_center GO:0005815 12133 413 49 2 1076 6 2 false 0.741435208952675 0.741435208952675 2.6476518998275E-310 Golgi_membrane GO:0000139 12133 322 49 1 1835 7 3 false 0.7415601437986994 0.7415601437986994 0.0 ncRNA_metabolic_process GO:0034660 12133 258 49 2 3294 33 1 false 0.7436695698680242 0.7436695698680242 0.0 maintenance_of_location GO:0051235 12133 184 49 1 4158 30 2 false 0.7440309714130102 0.7440309714130102 0.0 carboxylic_acid_transport GO:0046942 12133 137 49 1 184 1 2 false 0.7445652173913182 0.7445652173913182 5.817887468260403E-45 carboxylic_acid_binding GO:0031406 12133 186 49 1 2280 16 1 false 0.7449476719853563 0.7449476719853563 4.771798836819993E-279 regulation_of_mRNA_splicing,_via_spliceosome GO:0048024 12133 32 49 1 231 9 3 false 0.7453234433520137 0.7453234433520137 5.789429371590664E-40 regulation_of_adenylate_cyclase_activity GO:0045761 12133 103 49 1 138 1 4 false 0.7463768115942113 0.7463768115942113 1.4792034822830027E-33 early_endosome GO:0005769 12133 167 49 1 455 3 1 false 0.7473757913469177 0.7473757913469177 3.2726776377044107E-129 regulation_of_peptide_hormone_secretion GO:0090276 12133 131 49 1 175 1 3 false 0.7485714285714798 0.7485714285714798 2.0027366567035167E-42 metal_ion_transmembrane_transporter_activity GO:0046873 12133 263 49 1 527 2 2 false 0.749525616698638 0.749525616698638 6.55805140577772E-158 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 49 1 220 3 1 false 0.7497977766860263 0.7497977766860263 2.4407604211478482E-62 DNA_topoisomerase_II_activity GO:0061505 12133 6 49 1 8 1 1 false 0.7500000000000001 0.7500000000000001 0.035714285714285705 organic_acid_transport GO:0015849 12133 138 49 1 2569 25 2 false 0.7501821642348235 0.7501821642348235 8.315109453797594E-233 cellular_response_to_hormone_stimulus GO:0032870 12133 384 49 4 1510 19 3 false 0.7522450626434276 0.7522450626434276 0.0 lyase_activity GO:0016829 12133 230 49 1 4901 29 1 false 0.7529122583242165 0.7529122583242165 0.0 glycosyl_compound_catabolic_process GO:1901658 12133 956 49 11 2175 28 2 false 0.7540700099139503 0.7540700099139503 0.0 regionalization GO:0003002 12133 246 49 1 326 1 1 false 0.754601226993791 0.754601226993791 2.501957085662731E-78 Rho_protein_signal_transduction GO:0007266 12133 178 49 3 365 7 1 false 0.7549235823802274 0.7549235823802274 3.561371803691081E-109 positive_regulation_of_developmental_process GO:0051094 12133 603 49 3 4731 30 3 false 0.7555018454318386 0.7555018454318386 0.0 GDP_binding GO:0019003 12133 192 49 1 2280 16 3 false 0.7564329751478531 0.7564329751478531 2.6392786162156387E-285 regulation_of_lipid_metabolic_process GO:0019216 12133 182 49 1 4352 33 2 false 0.7570901523641569 0.7570901523641569 0.0 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 49 5 1399 15 3 false 0.7571431308570099 0.7571431308570099 0.0 transcription_corepressor_activity GO:0003714 12133 180 49 1 479 3 2 false 0.7576951469081828 0.7576951469081828 5.2319775680795235E-137 cell_junction GO:0030054 12133 588 49 2 10701 49 1 false 0.7593300807545778 0.7593300807545778 0.0 regulation_of_cell_morphogenesis GO:0022604 12133 267 49 2 1647 16 3 false 0.7597194756237333 0.7597194756237333 3.9027101E-316 protein_kinase_B_signaling_cascade GO:0043491 12133 98 49 1 806 11 1 false 0.7620203646045809 0.7620203646045809 6.677067387386742E-129 nitrogen_compound_transport GO:0071705 12133 428 49 3 2783 25 1 false 0.7636121724500408 0.7636121724500408 0.0 branching_morphogenesis_of_an_epithelial_tube GO:0048754 12133 137 49 1 267 2 2 false 0.7638759820900669 0.7638759820900669 9.47152683261942E-80 response_to_drug GO:0042493 12133 286 49 2 2369 22 1 false 0.7642313259219651 0.7642313259219651 0.0 endoplasmic_reticulum GO:0005783 12133 854 49 4 8213 49 2 false 0.7643450566351357 0.7643450566351357 0.0 proteasomal_protein_catabolic_process GO:0010498 12133 231 49 4 498 10 2 false 0.7648177614768569 0.7648177614768569 1.2543475178088858E-148 organelle_inner_membrane GO:0019866 12133 264 49 1 9083 49 3 false 0.7652411126153186 0.7652411126153186 0.0 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 49 11 2643 29 2 false 0.7653216526504318 0.7653216526504318 0.0 vasculature_development GO:0001944 12133 441 49 2 2686 16 2 false 0.765867526955635 0.765867526955635 0.0 regulation_of_protein_kinase_B_signaling_cascade GO:0051896 12133 80 49 1 646 11 2 false 0.7692533599430537 0.7692533599430537 1.7925842553941532E-104 cation_transmembrane_transporter_activity GO:0008324 12133 365 49 1 701 2 2 false 0.7706134094151502 0.7706134094151502 5.744660517109641E-210 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 49 12 1218 12 2 false 0.7709585115548149 0.7709585115548149 3.12960829510125E-54 cell_adhesion GO:0007155 12133 712 49 3 7542 42 2 false 0.7719295627621698 0.7719295627621698 0.0 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 49 1 136 1 2 false 0.7720588235294237 0.7720588235294237 2.4301849830786213E-31 cellular_lipid_metabolic_process GO:0044255 12133 606 49 3 7304 48 2 false 0.7728605686704917 0.7728605686704917 0.0 regulation_of_phospholipase_C_activity GO:1900274 12133 92 49 1 119 1 2 false 0.7731092436975002 0.7731092436975002 2.4296023527654974E-27 regulation_of_canonical_Wnt_receptor_signaling_pathway GO:0060828 12133 108 49 2 193 4 2 false 0.7734865904623296 0.7734865904623296 5.446526497036233E-57 glycoprotein_metabolic_process GO:0009100 12133 205 49 1 6720 48 3 false 0.7751659029204777 0.7751659029204777 0.0 centrosome GO:0005813 12133 327 49 2 3226 27 2 false 0.7754425592134706 0.7754425592134706 0.0 nucleotidyltransferase_activity GO:0016779 12133 123 49 1 1304 15 1 false 0.7756563187383847 0.7756563187383847 3.0641101871346933E-176 protein_acylation GO:0043543 12133 155 49 1 2370 22 1 false 0.7757266630362528 0.7757266630362528 6.767829300235778E-248 small_GTPase_binding GO:0031267 12133 126 49 3 137 3 1 false 0.7764419636468166 0.7764419636468166 1.8889221296599312E-16 alcohol_metabolic_process GO:0006066 12133 218 49 1 2438 16 2 false 0.7776690728295736 0.7776690728295736 4.437115E-318 steroid_metabolic_process GO:0008202 12133 182 49 1 5438 44 2 false 0.7777302414300664 0.7777302414300664 0.0 DNA-dependent_ATPase_activity GO:0008094 12133 71 49 1 228 4 1 false 0.7778608998293051 0.7778608998293051 6.772142656773899E-61 ubiquitin_thiolesterase_activity GO:0004221 12133 67 49 1 86 1 1 false 0.7790697674418556 0.7790697674418556 1.8312273425292562E-19 inositol_lipid-mediated_signaling GO:0048017 12133 173 49 1 1813 15 1 false 0.7791881265895004 0.7791881265895004 3.525454591975737E-247 protein_phosphatase_binding GO:0019903 12133 75 49 2 108 3 1 false 0.7793060208860243 0.7793060208860243 1.6262935863243163E-28 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 49 1 971 17 2 false 0.7797454193186343 0.7797454193186343 1.7939571902377886E-121 transmembrane_transport GO:0055085 12133 728 49 3 7606 42 2 false 0.7802067855229251 0.7802067855229251 0.0 lipid_biosynthetic_process GO:0008610 12133 360 49 2 4386 34 2 false 0.7814853217444448 0.7814853217444448 0.0 lymphocyte_homeostasis GO:0002260 12133 43 49 1 55 1 1 false 0.7818181818181777 0.7818181818181777 2.27930752242823E-12 cytoplasmic_sequestering_of_transcription_factor GO:0042994 12133 20 49 1 38 2 2 false 0.7823613086771004 0.7823613086771004 2.978140395000689E-11 GTPase_activator_activity GO:0005096 12133 192 49 1 732 5 4 false 0.7825829242023007 0.7825829242023007 3.4613287013713416E-182 protein_kinase_regulator_activity GO:0019887 12133 106 49 1 1026 14 3 false 0.7849760520925402 0.7849760520925402 2.0818014646962408E-147 cAMP_metabolic_process GO:0046058 12133 143 49 1 1194 12 2 false 0.7852704627858882 0.7852704627858882 2.6525041284959264E-189 ion_homeostasis GO:0050801 12133 532 49 1 677 1 1 false 0.7858197932053073 0.7858197932053073 5.041033537922393E-152 generation_of_a_signal_involved_in_cell-cell_signaling GO:0003001 12133 271 49 1 7541 42 2 false 0.7859208277491565 0.7859208277491565 0.0 signal_release GO:0023061 12133 271 49 1 7541 42 2 false 0.7859208277491565 0.7859208277491565 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 49 23 2805 23 1 false 0.7866477145571245 0.7866477145571245 1.0460685646312495E-69 regulation_of_transport GO:0051049 12133 942 49 7 3017 27 2 false 0.786687715545974 0.786687715545974 0.0 metal_ion_binding GO:0046872 12133 2699 49 11 2758 11 1 false 0.7879615763871749 0.7879615763871749 2.6200760259069314E-123 glycoprotein_biosynthetic_process GO:0009101 12133 174 49 1 3677 32 3 false 0.7894471274785686 0.7894471274785686 1.653253662203381E-303 vesicle_membrane GO:0012506 12133 312 49 1 9991 49 4 false 0.7895243952361877 0.7895243952361877 0.0 gland_development GO:0048732 12133 251 49 1 2873 17 2 false 0.7895862600812985 0.7895862600812985 0.0 cellular_protein_complex_disassembly GO:0043624 12133 149 49 7 154 7 1 false 0.7899739610029685 0.7899739610029685 1.4793035521715585E-9 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 49 2 859 13 3 false 0.7901886726858061 0.7901886726858061 3.480270935062193E-190 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 49 5 614 5 1 false 0.7912369415620175 0.7912369415620175 4.862693095923331E-49 positive_regulation_of_phospholipase_C_activity GO:0010863 12133 91 49 1 115 1 3 false 0.7913043478260915 0.7913043478260915 2.8677617706911523E-25 cellular_protein_complex_assembly GO:0043623 12133 284 49 3 958 13 2 false 0.7915078966950062 0.7915078966950062 4.57678794545446E-252 chromatin_organization GO:0006325 12133 539 49 3 689 4 1 false 0.7918358220602055 0.7918358220602055 4.375882251809235E-156 regulation_of_lipase_activity GO:0060191 12133 127 49 1 877 10 2 false 0.7925977705530587 0.7925977705530587 7.685839486208197E-157 acid-amino_acid_ligase_activity GO:0016881 12133 351 49 3 379 3 1 false 0.7938313165316235 0.7938313165316235 5.324332733169013E-43 negative_regulation_of_gene_expression GO:0010629 12133 817 49 6 3906 36 3 false 0.7948508641946194 0.7948508641946194 0.0 lipid_transport GO:0006869 12133 158 49 1 2581 25 3 false 0.7954394593111622 0.7954394593111622 2.1688704965711523E-257 RNA_localization GO:0006403 12133 131 49 1 1642 19 1 false 0.7958343098472181 0.7958343098472181 1.0675246049472868E-197 glucan_metabolic_process GO:0044042 12133 59 49 1 74 1 1 false 0.7972972972973 0.7972972972973 5.482425634220572E-16 carboxylic_acid_biosynthetic_process GO:0046394 12133 206 49 1 4363 33 3 false 0.7985297272633396 0.7985297272633396 0.0 regulation_of_protein_transport GO:0051223 12133 261 49 2 1665 18 3 false 0.7996175653333418 0.7996175653333418 3.65102727546E-313 response_to_calcium_ion GO:0051592 12133 78 49 1 189 3 1 false 0.7997000218526662 0.7997000218526662 3.918456545099658E-55 organic_acid_biosynthetic_process GO:0016053 12133 206 49 1 4345 33 3 false 0.7999004252593382 0.7999004252593382 0.0 regulation_of_cAMP_biosynthetic_process GO:0030817 12133 124 49 1 155 1 4 false 0.8000000000000121 0.8000000000000121 2.5860077232155615E-33 nucleobase-containing_compound_transport GO:0015931 12133 135 49 1 1584 18 2 false 0.800611973395303 0.800611973395303 1.0378441909200412E-199 lipid_binding GO:0008289 12133 571 49 2 8962 46 1 false 0.8008743409304534 0.8008743409304534 0.0 chromatin_binding GO:0003682 12133 309 49 1 8962 46 1 false 0.8017359879422059 0.8017359879422059 0.0 Fc-gamma_receptor_signaling_pathway GO:0038094 12133 72 49 4 76 4 1 false 0.8018784465792268 0.8018784465792268 7.79438414622254E-7 activation_of_cysteine-type_endopeptidase_activity GO:0097202 12133 85 49 1 106 1 1 false 0.801886792452837 0.801886792452837 1.25561322378657E-22 clathrin-coated_vesicle GO:0030136 12133 162 49 1 202 1 1 false 0.8019801980198291 0.8019801980198291 3.1333299685548734E-43 positive_regulation_of_gene_expression GO:0010628 12133 1008 49 8 4103 40 3 false 0.8024757641513993 0.8024757641513993 0.0 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 49 7 2528 19 3 false 0.8045671177370143 0.8045671177370143 0.0 nucleoside-triphosphatase_activity GO:0017111 12133 1059 49 11 1080 11 1 false 0.8049201158180093 0.8049201158180093 1.2343281293318376E-44 maintenance_of_protein_location_in_cell GO:0032507 12133 90 49 1 933 16 3 false 0.8054187776220335 0.8054187776220335 6.448935914517526E-128 cell_cycle_checkpoint GO:0000075 12133 202 49 3 217 3 1 false 0.8057966872670375 0.8057966872670375 1.925703524045096E-23 passive_transmembrane_transporter_activity GO:0022803 12133 304 49 1 544 2 1 false 0.8058173545663869 0.8058173545663869 2.1953421087848878E-161 organelle_assembly GO:0070925 12133 210 49 1 2677 20 2 false 0.806010442860999 0.806010442860999 7.5039E-319 adherens_junction_organization GO:0034332 12133 85 49 1 152 2 1 false 0.8073370512372312 0.8073370512372312 7.834980933972919E-45 positive_regulation_of_cell_migration GO:0030335 12133 206 49 1 736 5 3 false 0.807387018205538 0.807387018205538 9.676188091528093E-189 regulation_of_transmission_of_nerve_impulse GO:0051969 12133 160 49 1 2127 21 4 false 0.8080169130821133 0.8080169130821133 7.858109974637731E-246 regulation_of_intracellular_protein_transport GO:0033157 12133 160 49 2 847 15 3 false 0.8081567284327871 0.8081567284327871 1.5386851760422239E-177 cytoskeleton_organization GO:0007010 12133 719 49 3 2031 11 1 false 0.8082372392290036 0.8082372392290036 0.0 purine_nucleotide_binding GO:0017076 12133 1650 49 14 1997 18 1 false 0.8100607411626308 0.8100607411626308 0.0 monosaccharide_metabolic_process GO:0005996 12133 217 49 1 385 2 1 false 0.8102272727273129 0.8102272727273129 7.061110236111427E-114 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 49 2 2896 17 3 false 0.8108414732351813 0.8108414732351813 0.0 ribonucleotide_binding GO:0032553 12133 1651 49 14 1997 18 1 false 0.8116970755583753 0.8116970755583753 0.0 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 49 8 3847 39 4 false 0.8132930730434066 0.8132930730434066 0.0 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 49 8 3972 36 4 false 0.8133112816223493 0.8133112816223493 0.0 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 49 1 86 1 2 false 0.8139534883720972 0.8139534883720972 1.0344828145516245E-17 substrate-specific_channel_activity GO:0022838 12133 291 49 1 512 2 2 false 0.8141664628182496 0.8141664628182496 2.547694139879492E-151 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 49 1 81 1 2 false 0.8148148148148179 0.8148148148148179 1.2278945146862784E-16 positive_regulation_of_locomotion GO:0040017 12133 216 49 1 3440 26 3 false 0.8159277688731235 0.8159277688731235 0.0 regulation_of_hormone_secretion GO:0046883 12133 155 49 1 2003 21 5 false 0.8173603879301417 0.8173603879301417 3.773183112631131E-236 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 49 3 1541 13 3 false 0.8173924347777879 0.8173924347777879 0.0 regulation_of_insulin_secretion GO:0050796 12133 121 49 1 148 1 2 false 0.8175675675675318 0.8175675675675318 3.4478322296397875E-30 regulation_of_cell_activation GO:0050865 12133 303 49 1 6351 35 2 false 0.8201574549361426 0.8201574549361426 0.0 response_to_steroid_hormone_stimulus GO:0048545 12133 272 49 1 938 5 3 false 0.8203369754447682 0.8203369754447682 1.788442659003846E-244 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 49 11 1072 11 2 false 0.8206627625050398 0.8206627625050398 3.811291228230986E-41 synapse GO:0045202 12133 368 49 1 10701 49 1 false 0.8206934346707428 0.8206934346707428 0.0 ATPase_activity,_coupled GO:0042623 12133 228 49 4 307 6 1 false 0.8207230123474982 0.8207230123474982 1.7947531856464704E-75 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 49 3 1192 16 2 false 0.8209369927195732 0.8209369927195732 5.168872172755415E-294 Rho_GTPase_binding GO:0017048 12133 52 49 1 120 3 1 false 0.8215496368038911 0.8215496368038911 2.990284088371456E-35 peptide_hormone_secretion GO:0030072 12133 153 49 1 186 1 2 false 0.8225806451613688 0.8225806451613688 2.2720406169547848E-37 transmembrane_transporter_activity GO:0022857 12133 544 49 2 904 4 2 false 0.8233442994068068 0.8233442994068068 4.222056161945909E-263 RNA_export_from_nucleus GO:0006405 12133 72 49 1 165 3 2 false 0.8234788404772495 0.8234788404772495 1.3059643179360761E-48 positive_regulation_of_cellular_component_movement GO:0051272 12133 216 49 1 3234 25 3 false 0.8235661317863903 0.8235661317863903 0.0 cyclic_nucleotide_metabolic_process GO:0009187 12133 177 49 1 1317 12 1 false 0.8244388605691616 0.8244388605691616 5.758082552903037E-225 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 49 3 3447 21 2 false 0.8251140661905974 0.8251140661905974 0.0 DNA_damage_checkpoint GO:0000077 12133 126 49 1 574 7 2 false 0.8253955679674932 0.8253955679674932 1.5833464450994651E-130 positive_regulation_of_mitochondrial_membrane_permeability GO:0035794 12133 38 49 1 46 1 1 false 0.8260869565217287 0.8260869565217287 3.832404138206993E-9 mitochondrion GO:0005739 12133 1138 49 5 8213 49 2 false 0.8281035508239097 0.8281035508239097 0.0 regulation_of_purine_nucleotide_biosynthetic_process GO:1900371 12133 146 49 1 574 6 3 false 0.8296702050150014 0.8296702050150014 1.1371703790830463E-140 system_process GO:0003008 12133 1272 49 5 4095 21 1 false 0.8299176016137496 0.8299176016137496 0.0 protein_polyubiquitination GO:0000209 12133 163 49 1 548 5 1 false 0.830166587160386 0.830166587160386 3.681189236491621E-144 protein_deubiquitination GO:0016579 12133 64 49 1 77 1 1 false 0.8311688311688372 0.8311688311688372 5.4422836360017854E-15 positive_regulation_of_cell_differentiation GO:0045597 12133 439 49 2 3709 26 4 false 0.8312205694462308 0.8312205694462308 0.0 cellular_ion_homeostasis GO:0006873 12133 478 49 1 575 1 2 false 0.8313043478262244 0.8313043478262244 1.064446434652655E-112 regulation_of_biosynthetic_process GO:0009889 12133 3012 49 21 5483 43 2 false 0.8316484967645431 0.8316484967645431 0.0 prostaglandin_biosynthetic_process GO:0001516 12133 20 49 1 24 1 2 false 0.8333333333333302 0.8333333333333302 9.410878976096304E-5 neurotrophin_TRKA_receptor_binding GO:0005168 12133 5 49 1 6 1 1 false 0.8333333333333331 0.8333333333333331 0.1666666666666666 epithelial_cell_differentiation GO:0030855 12133 397 49 2 2228 17 2 false 0.8343604093895968 0.8343604093895968 0.0 positive_regulation_of_Rho_GTPase_activity GO:0032321 12133 70 49 1 156 3 2 false 0.8351003834874613 0.8351003834874613 3.8844004028867194E-46 amide_transport GO:0042886 12133 167 49 1 2393 25 2 false 0.8376517045679108 0.8376517045679108 2.949417857518552E-262 actin_cytoskeleton GO:0015629 12133 327 49 1 1430 7 1 false 0.8382743351343328 0.8382743351343328 0.0 regulation_of_hormone_levels GO:0010817 12133 272 49 1 2082 13 1 false 0.838892255105912 0.838892255105912 0.0 purine-containing_compound_catabolic_process GO:0072523 12133 959 49 11 1651 22 6 false 0.8392881757913765 0.8392881757913765 0.0 phospholipid_metabolic_process GO:0006644 12133 222 49 1 3035 24 3 false 0.8396270227614073 0.8396270227614073 0.0 protein_localization_to_mitochondrion GO:0070585 12133 67 49 1 516 13 1 false 0.8397541799838345 0.8397541799838345 5.765661430685337E-86 nucleoside-triphosphatase_regulator_activity GO:0060589 12133 361 49 2 1452 12 2 false 0.840169669467794 0.840169669467794 0.0 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 49 7 207 7 1 false 0.8405294364978887 0.8405294364978887 3.3148479610294504E-10 organic_hydroxy_compound_metabolic_process GO:1901615 12133 279 49 1 7451 48 1 false 0.8408283771574968 0.8408283771574968 0.0 cellular_metal_ion_homeostasis GO:0006875 12133 259 49 1 308 1 2 false 0.8409090909089498 0.8409090909089498 3.9623191237847456E-58 neurological_system_process GO:0050877 12133 894 49 3 1272 5 1 false 0.8410625404733736 0.8410625404733736 0.0 epithelium_development GO:0060429 12133 627 49 4 1132 9 1 false 0.8410865831463221 0.8410865831463221 0.0 embryonic_limb_morphogenesis GO:0030326 12133 90 49 1 107 1 2 false 0.8411214953271113 0.8411214953271113 4.308534738445919E-20 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 49 6 645 7 1 false 0.8413579038495537 0.8413579038495537 7.3138241320053254E-93 positive_regulation_of_intracellular_transport GO:0032388 12133 126 49 1 1370 19 3 false 0.8421104144610186 0.8421104144610186 5.304932497681123E-182 metal_ion_homeostasis GO:0055065 12133 278 49 1 330 1 1 false 0.8424242424241729 0.8424242424241729 6.131976736615521E-62 ion_channel_activity GO:0005216 12133 286 49 1 473 2 2 false 0.8442057548285732 0.8442057548285732 3.7303800171637374E-137 spindle GO:0005819 12133 221 49 1 4762 39 4 false 0.8444696582850395 0.8444696582850395 0.0 positive_regulation_of_cell_motility GO:2000147 12133 210 49 1 790 6 4 false 0.8444738970781135 0.8444738970781135 6.640105808226973E-198 anatomical_structure_development GO:0048856 12133 3099 49 18 3447 21 1 false 0.8447691739560637 0.8447691739560637 0.0 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 49 2 768 4 1 false 0.8448419271963574 0.8448419271963574 1.6461815804374103E-220 RNA_polymerase_II_transcription_factor_binding GO:0001085 12133 133 49 1 715 9 1 false 0.844936024821732 0.844936024821732 1.758868350294454E-148 pattern_specification_process GO:0007389 12133 326 49 1 4373 24 3 false 0.8450208804242524 0.8450208804242524 0.0 positive_regulation_of_cell_activation GO:0050867 12133 215 49 1 3002 25 3 false 0.8451932490272408 0.8451932490272408 0.0 transcription_cofactor_activity GO:0003712 12133 456 49 3 482 3 2 false 0.8464449927103619 0.8464449927103619 1.3948726648763881E-43 lipid_catabolic_process GO:0016042 12133 155 49 1 2566 30 2 false 0.8474381983591751 0.8474381983591751 2.0289846670236068E-253 positive_regulation_of_intracellular_protein_transport GO:0090316 12133 92 49 1 737 14 4 false 0.848105888828306 0.848105888828306 7.301092489476398E-120 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 49 2 252 4 2 false 0.8481365416131726 0.8481365416131726 5.925442745937436E-72 lymphocyte_activation GO:0046649 12133 403 49 1 475 1 1 false 0.8484210526316471 0.8484210526316471 3.3805466364584557E-87 organelle_membrane GO:0031090 12133 1619 49 6 9319 47 3 false 0.8494196296026487 0.8494196296026487 0.0 nucleosome_assembly GO:0006334 12133 94 49 1 154 2 3 false 0.8497580850520956 0.8497580850520956 2.9283606569953104E-44 GTP_metabolic_process GO:0046039 12133 625 49 5 1193 12 3 false 0.8502405974308703 0.8502405974308703 0.0 phospholipase_activity GO:0004620 12133 159 49 1 187 1 1 false 0.8502673796791042 0.8502673796791042 6.26556876547974E-34 multicellular_organismal_signaling GO:0035637 12133 604 49 2 5594 30 2 false 0.8504023344870322 0.8504023344870322 0.0 condensed_chromosome GO:0000793 12133 160 49 1 592 6 1 false 0.8504224252072546 0.8504224252072546 2.5509694139314793E-149 purine_ribonucleotide_binding GO:0032555 12133 1641 49 14 1660 14 2 false 0.8506085363850413 0.8506085363850413 8.870449707822982E-45 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 49 4 78 4 1 false 0.8520952731478723 0.8520952731478723 1.3144749986854762E-5 androgen_receptor_binding GO:0050681 12133 38 49 1 62 2 1 false 0.8540454785827765 0.8540454785827765 1.0311688046013243E-17 carbohydrate_metabolic_process GO:0005975 12133 515 49 2 7453 48 2 false 0.8541159896024476 0.8541159896024476 0.0 mRNA_transport GO:0051028 12133 106 49 1 124 1 1 false 0.8548387096773871 0.8548387096773871 4.872659948511352E-22 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 49 7 1225 8 2 false 0.854924816804767 0.854924816804767 5.928244845001387E-155 membrane GO:0016020 12133 4398 49 17 10701 49 1 false 0.8554717386328539 0.8554717386328539 0.0 substrate-specific_transmembrane_transporter_activity GO:0022891 12133 502 49 2 660 3 2 false 0.8559436140652248 0.8559436140652248 4.8010140095396714E-157 cyclin-dependent_protein_serine/threonine_kinase_activity GO:0004693 12133 105 49 1 709 12 2 false 0.8562603151356286 0.8562603151356286 1.7307728384071896E-128 regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030802 12133 143 49 1 167 1 3 false 0.856287425149713 0.856287425149713 1.5904574919997758E-29 protein_import_into_nucleus GO:0006606 12133 200 49 3 690 15 5 false 0.857821366992458 0.857821366992458 1.1794689955817937E-179 U5_snRNP GO:0005682 12133 80 49 4 93 5 1 false 0.8581769282086231 0.8581769282086231 3.852654648545616E-16 cellular_component_disassembly_involved_in_execution_phase_of_apoptosis GO:0006921 12133 80 49 1 372 8 2 false 0.8588684256429158 0.8588684256429158 1.5687432555814248E-83 male_gamete_generation GO:0048232 12133 271 49 2 355 3 1 false 0.8593388728202609 0.8593388728202609 8.83354474391846E-84 regulation_of_cell_migration GO:0030334 12133 351 49 2 749 6 2 false 0.8593770238253702 0.8593770238253702 5.057884988188172E-224 protein_homooligomerization GO:0051260 12133 183 49 2 288 4 1 false 0.8607674952345452 0.8607674952345452 1.8197847122731807E-81 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 49 3 178 6 1 false 0.8626628860087611 0.8626628860087611 1.7238002808689451E-50 Ras_GTPase_binding GO:0017016 12133 120 49 3 126 3 1 false 0.8627956989246989 0.8627956989246989 2.030392220357244E-10 hormone_transport GO:0009914 12133 189 49 1 2386 24 2 false 0.8633910057196604 0.8633910057196604 4.465203217560849E-286 response_to_virus GO:0009615 12133 230 49 1 475 3 1 false 0.8635953761622366 0.8635953761622366 3.548520767075247E-142 peptide_transport GO:0015833 12133 165 49 1 1580 18 2 false 0.864216893973817 0.864216893973817 6.47320563865109E-229 mitochondrial_inner_membrane GO:0005743 12133 241 49 1 382 2 2 false 0.8643690481097188 0.8643690481097188 1.3545216387089424E-108 actin_cytoskeleton_organization GO:0030036 12133 373 49 1 768 3 2 false 0.8644496902881873 0.8644496902881873 3.0657297438498186E-230 immune_system_development GO:0002520 12133 521 49 2 3460 22 2 false 0.8656532771785135 0.8656532771785135 0.0 inorganic_cation_transmembrane_transporter_activity GO:0022890 12133 316 49 1 365 1 1 false 0.8657534246575868 0.8657534246575868 4.982755146780477E-62 viral_genome_replication GO:0019079 12133 55 49 1 557 19 2 false 0.8659818117090146 0.8659818117090146 1.9020892479615726E-77 male_germ_cell_nucleus GO:0001673 12133 13 49 1 15 1 1 false 0.8666666666666659 0.8666666666666659 0.009523809523809518 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 49 1 1097 16 3 false 0.8668612962920634 0.8668612962920634 8.208279871491876E-172 positive_regulation_of_protein_transport GO:0051222 12133 154 49 1 1301 16 3 false 0.8684309890454426 0.8684309890454426 9.736449433094532E-205 small_conjugating_protein_ligase_activity GO:0019787 12133 335 49 3 351 3 1 false 0.8690303011221425 0.8690303011221425 5.577217121688537E-28 regulation_of_cAMP_metabolic_process GO:0030814 12133 133 49 1 465 6 3 false 0.8692490495255016 0.8692490495255016 3.255746313776628E-120 GTPase_activity GO:0003924 12133 612 49 5 1061 11 2 false 0.8706535665620452 0.8706535665620452 4.702100395E-313 response_to_oxygen-containing_compound GO:1901700 12133 864 49 6 2369 22 1 false 0.8707436569633366 0.8707436569633366 0.0 neuron_projection GO:0043005 12133 534 49 3 1043 8 2 false 0.8715648081028163 0.8715648081028163 5.7946905775E-313 chromosome,_centromeric_region GO:0000775 12133 148 49 1 512 6 1 false 0.8724236304301034 0.8724236304301034 5.05623540709124E-133 cytokine_receptor_binding GO:0005126 12133 172 49 1 918 10 1 false 0.8758305029875277 0.8758305029875277 1.4338329427110724E-191 organelle_fission GO:0048285 12133 351 49 1 2031 11 1 false 0.8766536281875208 0.8766536281875208 0.0 peptidyl-lysine_modification GO:0018205 12133 185 49 1 623 6 1 false 0.8804724343872099 0.8804724343872099 7.634244791194444E-164 cellular_glucan_metabolic_process GO:0006073 12133 59 49 1 67 1 2 false 0.8805970149253893 0.8805970149253893 1.5331870071919512E-10 microtubule GO:0005874 12133 288 49 1 3267 23 3 false 0.8811704941872642 0.8811704941872642 0.0 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 49 3 381 7 2 false 0.8823969953534825 0.8823969953534825 4.820433761728018E-112 ribonucleoside_metabolic_process GO:0009119 12133 1071 49 11 1083 11 1 false 0.8841428045764028 0.8841428045764028 1.9559437642804265E-28 small_molecule_biosynthetic_process GO:0044283 12133 305 49 1 2426 16 2 false 0.8843103090106132 0.8843103090106132 0.0 GTPase_regulator_activity GO:0030695 12133 351 49 2 621 5 2 false 0.8844204936419252 0.8844204936419252 7.115229923126785E-184 hemopoiesis GO:0030097 12133 462 49 2 491 2 1 false 0.8852487634564072 0.8852487634564072 1.8682876304369947E-47 heart_development GO:0007507 12133 343 49 1 2876 17 3 false 0.88529169095898 0.88529169095898 0.0 microtubule-based_process GO:0007017 12133 378 49 1 7541 42 1 false 0.8853574516173328 0.8853574516173328 0.0 organic_anion_transport GO:0015711 12133 184 49 1 1631 18 2 false 0.8854376231204197 0.8854376231204197 8.274450263154378E-249 regulation_of_neuron_projection_development GO:0010975 12133 182 49 1 686 7 3 false 0.8857363835582682 0.8857363835582682 1.2648422067158072E-171 regulation_of_translation GO:0006417 12133 210 49 1 3605 36 4 false 0.8859971465620126 0.8859971465620126 0.0 cytoskeletal_part GO:0044430 12133 1031 49 5 5573 40 2 false 0.8867175617302467 0.8867175617302467 0.0 nucleoside_catabolic_process GO:0009164 12133 952 49 11 1516 21 5 false 0.8879042810428608 0.8879042810428608 0.0 glucose_metabolic_process GO:0006006 12133 183 49 1 206 1 1 false 0.888349514563178 0.888349514563178 5.590923529140016E-31 response_to_decreased_oxygen_levels GO:0036293 12133 202 49 2 214 2 1 false 0.8907463472423881 0.8907463472423881 7.108512362452622E-20 transmission_of_nerve_impulse GO:0019226 12133 586 49 2 4105 25 3 false 0.8909428305308271 0.8909428305308271 0.0 cytoskeletal_protein_binding GO:0008092 12133 556 49 2 6397 42 1 false 0.8910802073106241 0.8910802073106241 0.0 regulation_of_mRNA_stability GO:0043488 12133 33 49 1 37 1 1 false 0.8918918918918968 0.8918918918918968 1.5141191611779804E-5 lipid_localization GO:0010876 12133 181 49 1 1642 19 1 false 0.8926960009693414 0.8926960009693414 1.1319861049738569E-246 ion_transmembrane_transporter_activity GO:0015075 12133 469 49 2 589 3 2 false 0.8928807979173973 0.8928807979173973 1.1842155919657181E-128 positive_regulation_of_leukocyte_activation GO:0002696 12133 206 49 1 756 7 4 false 0.8932576270408341 0.8932576270408341 1.5163059036704027E-191 mitochondrial_part GO:0044429 12133 557 49 2 7185 48 3 false 0.8961293957515213 0.8961293957515213 0.0 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 49 11 1014 11 1 false 0.896225032019661 0.896225032019661 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 49 11 1014 11 1 false 0.896225032019661 0.896225032019661 3.301546202575714E-24 plasma_membrane_part GO:0044459 12133 1329 49 4 10213 49 3 false 0.8965566618078377 0.8965566618078377 0.0 covalent_chromatin_modification GO:0016569 12133 312 49 1 458 2 1 false 0.8988562200800765 0.8988562200800765 7.826311589520491E-124 single-organism_biosynthetic_process GO:0044711 12133 313 49 1 5633 40 2 false 0.8992326103277003 0.8992326103277003 0.0 response_to_extracellular_stimulus GO:0009991 12133 260 49 1 1046 8 1 false 0.8992465891509783 0.8992465891509783 6.4524154237794786E-254 second-messenger-mediated_signaling GO:0019932 12133 257 49 1 1813 15 1 false 0.9000003735238241 0.9000003735238241 1.643E-320 negative_regulation_of_cell_cycle GO:0045786 12133 298 49 1 3131 23 3 false 0.9006310880153107 0.9006310880153107 0.0 striated_muscle_tissue_development GO:0014706 12133 285 49 3 295 3 1 false 0.9013898612028302 0.9013898612028302 8.482306621073292E-19 insulin_secretion GO:0030073 12133 138 49 1 153 1 1 false 0.901960784313682 0.901960784313682 4.508804313440429E-21 ubiquitin-specific_protease_activity GO:0004843 12133 46 49 1 51 1 1 false 0.9019607843137332 0.9019607843137332 4.2570219577192243E-7 ribose_phosphate_biosynthetic_process GO:0046390 12133 279 49 1 1586 12 3 false 0.9027722655070747 0.9027722655070747 1.5665E-319 canonical_Wnt_receptor_signaling_pathway GO:0060070 12133 152 49 2 260 5 1 false 0.9027811379523004 0.9027811379523004 4.5351475920205146E-76 protein_acetylation GO:0006473 12133 140 49 1 155 1 1 false 0.9032258064516349 0.9032258064516349 3.675799410957308E-21 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 49 21 4544 43 3 false 0.9038210580542312 0.9038210580542312 0.0 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 49 5 1053 11 1 false 0.9043478622857127 0.9043478622857127 1.6418245301060377E-306 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 49 6 378 6 1 false 0.9078751437642244 0.9078751437642244 2.5686196448553377E-13 small_ribosomal_subunit GO:0015935 12133 60 49 2 132 7 1 false 0.9079560102508866 0.9079560102508866 4.556510204279982E-39 regulation_of_cyclic_nucleotide_metabolic_process GO:0030799 12133 156 49 1 478 6 2 false 0.9079758897124062 0.9079758897124062 1.998151187516486E-130 endoplasmic_reticulum_unfolded_protein_response GO:0030968 12133 82 49 1 118 2 3 false 0.908735332464137 0.908735332464137 3.7748187458517594E-31 purine-containing_compound_biosynthetic_process GO:0072522 12133 280 49 1 4251 35 6 false 0.9087995347463402 0.9087995347463402 0.0 ionotropic_glutamate_receptor_binding GO:0035255 12133 15 49 1 22 2 1 false 0.90909090909091 0.90909090909091 5.863589454920721E-6 cellular_process_involved_in_reproduction_in_multicellular_organism GO:0022412 12133 136 49 1 756 12 2 false 0.9092122645485501 0.9092122645485501 5.066786164679353E-154 heme_binding GO:0020037 12133 72 49 1 79 1 1 false 0.9113924050632815 0.9113924050632815 3.4497584076401995E-10 protein_localization_to_nucleus GO:0034504 12133 233 49 4 516 13 1 false 0.9117148247728547 0.9117148247728547 1.4955266190313754E-153 transcription,_DNA-dependent GO:0006351 12133 2643 49 20 4063 36 3 false 0.9137229998100898 0.9137229998100898 0.0 internal_protein_amino_acid_acetylation GO:0006475 12133 128 49 1 140 1 1 false 0.914285714285699 0.914285714285699 1.3721041217101573E-17 response_to_nutrient_levels GO:0031667 12133 238 49 1 260 1 1 false 0.9153846153846938 0.9153846153846938 2.081158575166241E-32 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 49 1 3799 38 1 false 0.9154927857475822 0.9154927857475822 0.0 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 49 2 4947 37 2 false 0.9158655823900645 0.9158655823900645 0.0 actin_filament-based_process GO:0030029 12133 431 49 1 7541 42 1 false 0.9161524331342541 0.9161524331342541 0.0 DNA_recombination GO:0006310 12133 190 49 1 791 9 1 false 0.916827286918658 0.916827286918658 1.2250789605162758E-188 nucleic_acid_transport GO:0050657 12133 124 49 1 135 1 1 false 0.9185185185185545 0.9185185185185545 2.2345648964967124E-16 adherens_junction GO:0005912 12133 181 49 1 197 1 1 false 0.9187817258882387 0.9187817258882387 7.602023639007691E-24 cellular_response_to_organic_cyclic_compound GO:0071407 12133 190 49 1 1540 19 2 false 0.9193504159387147 0.9193504159387147 4.3845861432353096E-249 cytoplasmic_vesicle_part GO:0044433 12133 366 49 1 7185 48 3 false 0.9193820274736025 0.9193820274736025 0.0 organ_morphogenesis GO:0009887 12133 649 49 2 2908 17 3 false 0.9202283692093368 0.9202283692093368 0.0 enzyme_inhibitor_activity GO:0004857 12133 240 49 1 1075 10 2 false 0.9210196033086114 0.9210196033086114 4.258934911432728E-247 regulation_of_system_process GO:0044057 12133 373 49 1 2254 14 2 false 0.9211873117065292 0.9211873117065292 0.0 regulation_of_protein_ubiquitination GO:0031396 12133 176 49 1 1344 18 2 false 0.9214286484036365 0.9214286484036365 8.0617715234352E-226 regulation_of_cell_projection_organization GO:0031344 12133 227 49 1 1532 16 2 false 0.9242003994331096 0.9242003994331096 2.603761260472357E-278 protein_N-linked_glycosylation_via_asparagine GO:0018279 12133 61 49 1 66 1 2 false 0.924242424242419 0.924242424242419 1.1189527318559458E-7 regulation_of_secretion GO:0051046 12133 367 49 1 1193 7 2 false 0.9243227340391846 0.9243227340391846 6.7239E-319 response_to_organic_cyclic_compound GO:0014070 12133 487 49 3 1783 19 1 false 0.9258071417660987 0.9258071417660987 0.0 lytic_vacuole GO:0000323 12133 258 49 2 310 3 1 false 0.9259321323836572 0.9259321323836572 2.1177419387644615E-60 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 49 2 7293 42 3 false 0.9264339719276143 0.9264339719276143 0.0 guanyl_nucleotide_binding GO:0019001 12133 450 49 2 1650 14 1 false 0.928455091729548 0.928455091729548 0.0 nuclear_division GO:0000280 12133 326 49 1 351 1 1 false 0.9287749287750802 0.9287749287750802 8.671827254018066E-39 embryonic_morphogenesis GO:0048598 12133 406 49 1 2812 17 3 false 0.9299826382922356 0.9299826382922356 0.0 guanyl_ribonucleotide_binding GO:0032561 12133 450 49 2 1641 14 2 false 0.9300600345589918 0.9300600345589918 0.0 transition_metal_ion_binding GO:0046914 12133 1457 49 4 2699 11 1 false 0.9306571247570712 0.9306571247570712 0.0 regulation_of_cell_development GO:0060284 12133 446 49 2 1519 13 2 false 0.9310142551571111 0.9310142551571111 0.0 regulation_of_peptidyl-tyrosine_phosphorylation GO:0050730 12133 150 49 1 812 13 2 false 0.9312356463591618 0.9312356463591618 5.072476466269739E-168 cell-cell_signaling GO:0007267 12133 859 49 3 3969 25 2 false 0.9313581520720412 0.9313581520720412 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 49 21 4972 42 3 false 0.9320207844946957 0.9320207844946957 0.0 purine_nucleoside_binding GO:0001883 12133 1631 49 14 1639 14 1 false 0.9335362298342772 0.9335362298342772 7.876250956196666E-22 response_to_hormone_stimulus GO:0009725 12133 611 49 4 1784 19 2 false 0.9336514959660194 0.9336514959660194 0.0 sex_differentiation GO:0007548 12133 202 49 1 340 3 1 false 0.9340001047283858 0.9340001047283858 4.342696063294865E-99 activation_of_phospholipase_C_activity GO:0007202 12133 85 49 1 91 1 1 false 0.9340659340659245 0.9340659340659245 1.5002312651502098E-9 homeostatic_process GO:0042592 12133 990 49 4 2082 13 1 false 0.9346758697271255 0.9346758697271255 0.0 cation_transport GO:0006812 12133 606 49 2 833 4 1 false 0.9360578328622643 0.9360578328622643 4.047492354513465E-211 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 49 11 1007 11 2 false 0.9360682142659145 0.9360682142659145 7.008686204750717E-16 protein_tyrosine_kinase_activity GO:0004713 12133 180 49 1 1014 14 1 false 0.9364233280179458 0.9364233280179458 3.660578992202259E-205 GTP_binding GO:0005525 12133 292 49 1 1635 14 3 false 0.937117793307638 0.937117793307638 0.0 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 49 11 1587 23 3 false 0.9373423943749638 0.9373423943749638 0.0 limb_morphogenesis GO:0035108 12133 107 49 1 114 1 2 false 0.9385964912280663 0.9385964912280663 2.4303191085943817E-11 chromatin GO:0000785 12133 287 49 2 512 6 1 false 0.9387819654639951 0.9387819654639951 9.050120143931621E-152 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 49 1 2935 22 1 false 0.9389322496533745 0.9389322496533745 0.0 regulation_of_stress-activated_protein_kinase_signaling_cascade GO:0070302 12133 147 49 1 765 13 3 false 0.9391040394907988 0.9391040394907988 7.281108340064304E-162 activating_transcription_factor_binding GO:0033613 12133 294 49 2 715 9 1 false 0.9391895302592115 0.9391895302592115 1.6086726333731214E-209 Golgi_apparatus_part GO:0044431 12133 406 49 1 7185 48 3 false 0.9392755947669476 0.9392755947669476 0.0 stress-activated_MAPK_cascade GO:0051403 12133 207 49 2 504 9 2 false 0.9393370801652658 0.9393370801652658 1.7060805667457382E-147 chromatin_modification GO:0016568 12133 458 49 2 539 3 1 false 0.9395362201059612 0.9395362201059612 1.802023694196357E-98 regulation_of_neuron_differentiation GO:0045664 12133 281 49 1 853 7 2 false 0.9397658175182078 0.9397658175182078 5.679328733626827E-234 nucleocytoplasmic_transport GO:0006913 12133 327 49 5 331 5 1 false 0.9406689703262207 0.9406689703262207 2.036102168267257E-9 nucleoside_phosphate_biosynthetic_process GO:1901293 12133 323 49 1 4156 35 3 false 0.9417970627268846 0.9417970627268846 0.0 androgen_receptor_signaling_pathway GO:0030521 12133 62 49 1 102 3 1 false 0.9424577751892574 0.9424577751892574 2.6706454874295595E-29 ncRNA_processing GO:0034470 12133 186 49 2 649 14 2 false 0.9433126417837296 0.9433126417837296 4.048832162241149E-168 purine_nucleotide_biosynthetic_process GO:0006164 12133 269 49 1 1265 12 3 false 0.9440418149192948 0.9440418149192948 1.9379490968147627E-283 response_to_lipid GO:0033993 12133 515 49 3 1783 19 1 false 0.9440844628237373 0.9440844628237373 0.0 GTP_catabolic_process GO:0006184 12133 614 49 5 957 11 4 false 0.9442314624531111 0.9442314624531111 2.3934835856107606E-270 receptor-mediated_endocytosis GO:0006898 12133 157 49 1 411 6 1 false 0.9455449371868854 0.9455449371868854 4.873503831957431E-118 internal_peptidyl-lysine_acetylation GO:0018393 12133 124 49 1 131 1 2 false 0.9465648854961779 0.9465648854961779 8.960493506706349E-12 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 49 4 149 4 1 false 0.9468528931616569 0.9468528931616569 9.06947215672054E-5 JNK_cascade GO:0007254 12133 159 49 1 207 2 1 false 0.9470944139580413 0.9470944139580413 3.1556682987155503E-48 mitosis GO:0007067 12133 326 49 1 953 7 2 false 0.9472505406695634 0.9472505406695634 4.8424843971573165E-265 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 49 5 956 11 2 false 0.9473043371352223 0.9473043371352223 3.936677708897206E-269 ubiquitin-protein_ligase_activity GO:0004842 12133 321 49 2 558 6 2 false 0.9473668496799156 0.9473668496799156 1.7708856343357755E-164 response_to_unfolded_protein GO:0006986 12133 126 49 1 133 1 1 false 0.9473684210526476 0.9473684210526476 8.038720251232349E-12 cell_migration GO:0016477 12133 734 49 5 785 6 1 false 0.9475275175878457 0.9475275175878457 1.8763224028220524E-81 phospholipid_binding GO:0005543 12133 403 49 1 2392 16 2 false 0.9482938526505968 0.9482938526505968 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 49 6 400 7 2 false 0.9486881407397041 0.9486881407397041 1.150456419433401E-36 hexose_metabolic_process GO:0019318 12133 206 49 1 217 1 1 false 0.9493087557602818 0.9493087557602818 1.0279992997812003E-18 purine_ribonucleoside_binding GO:0032550 12133 1629 49 14 1635 14 2 false 0.9496357549497613 0.9496357549497613 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 49 14 1639 14 1 false 0.9497562285849342 0.9497562285849342 3.7483303336303164E-17 purine_ribonucleotide_biosynthetic_process GO:0009152 12133 265 49 1 1206 12 3 false 0.9498621630752238 0.9498621630752238 5.7559641067065754E-275 ribonucleotide_biosynthetic_process GO:0009260 12133 275 49 1 1250 12 3 false 0.9500400537788227 0.9500400537788227 3.3374763917028038E-285 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 49 5 199 5 1 false 0.9502563321658456 0.9502563321658456 5.075884472869322E-5 integral_to_membrane GO:0016021 12133 2318 49 2 2375 2 1 false 0.952566133110128 0.952566133110128 3.0839384482043954E-116 histone_modification GO:0016570 12133 306 49 1 2375 22 2 false 0.9525929228091217 0.9525929228091217 0.0 establishment_of_protein_localization_to_mitochondrion GO:0072655 12133 66 49 1 211 8 2 false 0.9532627725295859 0.9532627725295859 1.9619733177914497E-56 regulation_of_nervous_system_development GO:0051960 12133 381 49 1 1805 13 2 false 0.9546707604026144 0.9546707604026144 0.0 repressing_transcription_factor_binding GO:0070491 12133 207 49 1 715 9 1 false 0.9548120226666581 0.9548120226666581 4.3536836236667346E-186 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 49 7 2849 26 1 false 0.9557149824014116 0.9557149824014116 0.0 DNA_integrity_checkpoint GO:0031570 12133 130 49 1 202 3 1 false 0.9559332052607724 0.9559332052607724 1.23666756413938E-56 peptide_binding GO:0042277 12133 178 49 2 182 2 1 false 0.9564082326512648 0.9564082326512648 2.2611831618281403E-8 protein_complex_assembly GO:0006461 12133 743 49 9 1214 20 3 false 0.9565590038213051 0.9565590038213051 0.0 hydrolase_activity,_acting_on_ester_bonds GO:0016788 12133 814 49 3 2556 18 1 false 0.9574343059770327 0.9574343059770327 0.0 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 49 11 1085 11 1 false 0.9600050591336591 0.9600050591336591 1.7413918354446858E-11 perinuclear_region_of_cytoplasm GO:0048471 12133 416 49 1 5117 38 1 false 0.9606144705750246 0.9606144705750246 0.0 protein_targeting_to_nucleus GO:0044744 12133 200 49 3 443 12 1 false 0.9607764480926142 0.9607764480926142 9.352491047681514E-132 positive_regulation_of_cysteine-type_endopeptidase_activity GO:2001056 12133 106 49 1 224 5 3 false 0.9610589426436591 0.9610589426436591 9.593761035739944E-67 activation_of_adenylate_cyclase_activity GO:0007190 12133 50 49 1 52 1 1 false 0.9615384615384723 0.9615384615384723 7.54147812971345E-4 spindle_assembly_checkpoint GO:0071173 12133 36 49 1 45 2 1 false 0.9636363636363635 0.9636363636363635 1.1284603934692157E-9 Golgi_apparatus GO:0005794 12133 828 49 2 8213 49 2 false 0.9648048815966568 0.9648048815966568 0.0 secretion_by_cell GO:0032940 12133 578 49 1 7547 42 3 false 0.965125199781627 0.965125199781627 0.0 protein_ubiquitination GO:0016567 12133 548 49 5 578 6 1 false 0.9656811024927741 0.9656811024927741 7.913703273197485E-51 nucleotide_biosynthetic_process GO:0009165 12133 322 49 1 1318 12 2 false 0.9658769071048519 0.9658769071048519 2.1862113E-317 cation_binding GO:0043169 12133 2758 49 11 4448 24 1 false 0.9659019507434906 0.9659019507434906 0.0 oxidation-reduction_process GO:0055114 12133 740 49 2 2877 18 1 false 0.9661281120290188 0.9661281120290188 0.0 cellular_homeostasis GO:0019725 12133 585 49 1 7566 42 2 false 0.9662714802786865 0.9662714802786865 0.0 response_to_radiation GO:0009314 12133 293 49 1 676 6 1 false 0.9674849447560223 0.9674849447560223 4.1946042901139895E-200 regulation_of_stress-activated_MAPK_cascade GO:0032872 12133 146 49 1 463 9 3 false 0.9681203375765 0.9681203375765 1.1657182873431035E-124 regulation_of_leukocyte_activation GO:0002694 12133 278 49 1 948 10 3 false 0.9695181565938363 0.9695181565938363 2.7935655578419027E-248 viral_reproduction GO:0016032 12133 633 49 19 634 19 1 false 0.9700315457414661 0.9700315457414661 0.0015772870662463625 enzyme_activator_activity GO:0008047 12133 321 49 1 1413 14 2 false 0.9734022852191863 0.9734022852191863 0.0 regulation_of_neurogenesis GO:0050767 12133 344 49 1 1039 9 4 false 0.9736473585024764 0.9736473585024764 1.1807712079388562E-285 chordate_embryonic_development GO:0043009 12133 471 49 2 477 2 1 false 0.974974895618767 0.974974895618767 6.308586670641318E-14 inflammatory_response GO:0006954 12133 381 49 1 1437 12 2 false 0.9756082215067723 0.9756082215067723 0.0 focal_adhesion GO:0005925 12133 122 49 1 125 1 1 false 0.9759999999999686 0.9759999999999686 3.1471282454758027E-6 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 49 20 3611 32 3 false 0.9761533466739285 0.9761533466739285 0.0 cellular_protein_modification_process GO:0006464 12133 2370 49 22 3038 34 2 false 0.9771846702834218 0.9771846702834218 0.0 protein_homodimerization_activity GO:0042803 12133 471 49 2 1035 10 2 false 0.9788852482058238 0.9788852482058238 7.159384282986134E-309 organophosphate_biosynthetic_process GO:0090407 12133 477 49 1 4948 38 2 false 0.9790862960638621 0.9790862960638621 0.0 phosphotyrosine_binding GO:0001784 12133 13 49 1 19 3 1 false 0.979360165118681 0.979360165118681 3.6856848002358886E-5 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 49 6 672 17 1 false 0.9797422603174206 0.9797422603174206 6.935915883902889E-199 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 49 20 4395 40 3 false 0.979934896264447 0.979934896264447 0.0 receptor_activity GO:0004872 12133 790 49 1 10257 49 1 false 0.9804907658767046 0.9804907658767046 0.0 membrane_part GO:0044425 12133 2995 49 8 10701 49 2 false 0.9810195137744888 0.9810195137744888 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 49 12 1319 12 1 false 0.9818803273272403 0.9818803273272403 1.1504554077729292E-6 carboxylic_acid_metabolic_process GO:0019752 12133 614 49 1 7453 48 2 false 0.9840843763515721 0.9840843763515721 0.0 epithelium_migration GO:0090132 12133 130 49 2 131 2 1 false 0.9847328244274453 0.9847328244274453 0.007633587786259341 leukocyte_activation GO:0045321 12133 475 49 1 1729 13 2 false 0.984896801145482 0.984896801145482 0.0 organonitrogen_compound_biosynthetic_process GO:1901566 12133 548 49 1 5099 37 2 false 0.9853397189160633 0.9853397189160633 0.0 cytoskeleton GO:0005856 12133 1430 49 7 3226 27 1 false 0.9854069236438263 0.9854069236438263 0.0 sexual_reproduction GO:0019953 12133 407 49 3 1345 23 1 false 0.9858948049576111 0.9858948049576111 0.0 phosphatase_activity GO:0016791 12133 306 49 1 465 4 2 false 0.9866683297845483 0.9866683297845483 4.9712656169712896E-129 oxoacid_metabolic_process GO:0043436 12133 667 49 1 676 1 1 false 0.9866863905329417 0.9866863905329417 1.2985791548492531E-20 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 49 19 3220 30 4 false 0.9890652560476318 0.9890652560476318 0.0 ion_transport GO:0006811 12133 833 49 4 2323 24 1 false 0.9896233063074777 0.9896233063074777 0.0 pyrophosphatase_activity GO:0016462 12133 1080 49 11 1081 11 1 false 0.9898242368169569 0.9898242368169569 9.250693802031629E-4 chemical_homeostasis GO:0048878 12133 677 49 1 990 4 1 false 0.9901391255124399 0.9901391255124399 1.9931274413677286E-267 myotube_differentiation GO:0014902 12133 44 49 1 57 3 1 false 0.9902255639097692 0.9902255639097692 4.0844733797899586E-13 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 49 3 723 9 2 false 0.9902747866424313 0.9902747866424313 2.0953844092707462E-201 organic_acid_metabolic_process GO:0006082 12133 676 49 1 7326 48 2 false 0.9905594234979255 0.9905594234979255 0.0 regulation_of_gene_expression GO:0010468 12133 2935 49 22 4361 43 2 false 0.9910510444498442 0.9910510444498442 0.0 positive_regulation_of_cell_proliferation GO:0008284 12133 558 49 1 3155 25 3 false 0.9924509814709455 0.9924509814709455 0.0 spermatogenesis GO:0007283 12133 270 49 2 271 2 1 false 0.9926199261993315 0.9926199261993315 0.0036900369003690227 apoptotic_process GO:0006915 12133 1373 49 14 1385 15 1 false 0.993209407952703 0.993209407952703 1.0085392941984968E-29 response_to_other_organism GO:0051707 12133 475 49 3 1194 20 2 false 0.9964050161726433 0.9964050161726433 0.0 multicellular_organismal_reproductive_process GO:0048609 12133 477 49 3 1275 22 2 false 0.9969759729378731 0.9969759729378731 0.0 membrane-bounded_vesicle GO:0031988 12133 762 49 2 834 4 1 false 0.9976778499174307 0.9976778499174307 6.820230733401612E-106 DNA_binding GO:0003677 12133 2091 49 12 2849 26 1 false 0.9992430276809986 0.9992430276809986 0.0 secretion GO:0046903 12133 661 49 1 2323 24 1 false 0.999691486472336 0.999691486472336 0.0 intrinsic_to_membrane GO:0031224 12133 2375 49 2 2995 8 1 false 0.9998959090010966 0.9998959090010966 0.0 protein_complex GO:0043234 12133 2976 49 21 3462 36 1 false 0.9999913373436594 0.9999913373436594 0.0 GO:0000000 12133 11221 49 49 0 0 0 true 1.0 1.0 1.0 telomerase_activity GO:0003720 12133 21 49 1 21 1 1 true 1.0 1.0 1.0 adenosylhomocysteinase_activity GO:0004013 12133 3 49 1 3 1 1 true 1.0 1.0 1.0 lysosome GO:0005764 12133 258 49 2 258 2 1 true 1.0 1.0 1.0 prostaglandin_metabolic_process GO:0006693 12133 24 49 1 24 1 1 true 1.0 1.0 1.0 blood_circulation GO:0008015 12133 307 49 2 307 2 1 true 1.0 1.0 1.0 macrophage_derived_foam_cell_differentiation GO:0010742 12133 26 49 1 26 1 1 true 1.0 1.0 1.0 channel_activity GO:0015267 12133 304 49 1 304 1 1 true 1.0 1.0 1.0 Sin3_complex GO:0016580 12133 12 49 1 12 1 1 true 1.0 1.0 1.0 cholesterol_transport GO:0030301 12133 50 49 1 50 1 1 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 49 4 147 4 1 true 1.0 1.0 1.0 protein_localization_to_microtubule GO:0035372 12133 5 49 1 5 1 1 true 1.0 1.0 1.0 slit_diaphragm GO:0036057 12133 6 49 1 6 1 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 49 1 87 1 1 true 1.0 1.0 1.0 hypermethylation_of_CpG_island GO:0044027 12133 3 49 1 3 1 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 49 7 1169 7 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 49 12 417 12 1 true 1.0 1.0 1.0 phosphatidylinositol-mediated_signaling GO:0048015 12133 173 49 1 173 1 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 49 1 124 1 2 true 1.0 1.0 1.0 limb_development GO:0060173 12133 114 49 1 114 1 1 true 1.0 1.0 1.0 glomerular_visceral_epithelial_cell_differentiation GO:0072112 12133 14 49 1 14 1 2 true 1.0 1.0 1.0