ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min ribonucleoprotein_complex GO:0030529 12133 569 42 14 9264 41 2 false 6.975220543161354E-8 6.975220543161354E-8 0.0 translational_initiation GO:0006413 12133 160 42 8 7667 35 2 false 4.4021398825070863E-7 4.4021398825070863E-7 0.0 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 42 8 1239 9 2 false 4.679304551030261E-6 4.679304551030261E-6 4.427655683668096E-244 organelle GO:0043226 12133 7980 42 41 10701 41 1 false 5.8121727425520804E-6 5.8121727425520804E-6 0.0 RNA_catabolic_process GO:0006401 12133 203 42 9 4368 31 3 false 7.00293478727186E-6 7.00293478727186E-6 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 42 14 6457 37 3 false 9.531724920263317E-6 9.531724920263317E-6 0.0 macromolecular_complex GO:0032991 12133 3462 42 27 10701 41 1 false 1.0853469502031202E-5 1.0853469502031202E-5 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 42 37 7569 37 2 false 1.5220354466881462E-5 1.5220354466881462E-5 0.0 organelle_part GO:0044422 12133 5401 42 34 10701 41 2 false 1.5852114957992297E-5 1.5852114957992297E-5 0.0 translational_elongation GO:0006414 12133 121 42 7 3388 25 2 false 1.75418555486862E-5 1.75418555486862E-5 5.332026529203484E-226 mRNA_metabolic_process GO:0016071 12133 573 42 15 3294 30 1 false 4.009794732497698E-5 4.009794732497698E-5 0.0 macromolecule_catabolic_process GO:0009057 12133 820 42 14 6846 37 2 false 4.8044162015959625E-5 4.8044162015959625E-5 0.0 ribosomal_subunit GO:0044391 12133 132 42 6 7199 37 4 false 4.943186092374502E-5 4.943186092374502E-5 2.5906239763169356E-285 translation_regulator_activity GO:0045182 12133 21 42 3 10260 42 2 false 8.05984652978471E-5 8.05984652978471E-5 3.0418957762761004E-65 Prp19_complex GO:0000974 12133 78 42 5 2976 19 1 false 9.483575124565653E-5 9.483575124565653E-5 3.570519754703887E-156 cellular_process_involved_in_reproduction GO:0048610 12133 469 42 9 9699 40 2 false 9.563284170048856E-5 9.563284170048856E-5 0.0 cytosolic_part GO:0044445 12133 178 42 6 5117 24 2 false 1.2997820326183656E-4 1.2997820326183656E-4 0.0 translation GO:0006412 12133 457 42 11 5433 37 3 false 1.5044024065010033E-4 1.5044024065010033E-4 0.0 multi-organism_cellular_process GO:0044764 12133 634 42 10 9702 40 2 false 1.8675092774030695E-4 1.8675092774030695E-4 0.0 regulation_of_biological_quality GO:0065008 12133 2082 42 17 6908 26 1 false 2.1235439916644002E-4 2.1235439916644002E-4 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 42 31 6846 37 2 false 2.6501336886987977E-4 2.6501336886987977E-4 0.0 viral_transcription GO:0019083 12133 145 42 6 2964 21 3 false 3.643368350864719E-4 3.643368350864719E-4 1.0927707330622845E-250 cytosol GO:0005829 12133 2226 42 19 5117 24 1 false 3.943276137600808E-4 3.943276137600808E-4 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 42 37 7451 37 1 false 4.459794255692564E-4 4.459794255692564E-4 0.0 ribosome GO:0005840 12133 210 42 6 6755 36 3 false 7.499827537997174E-4 7.499827537997174E-4 0.0 intracellular_organelle_part GO:0044446 12133 5320 42 34 9083 41 3 false 7.93002825384382E-4 7.93002825384382E-4 0.0 cytosolic_ribosome GO:0022626 12133 92 42 6 296 6 2 false 8.032655512874072E-4 8.032655512874072E-4 4.2784789004852985E-79 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 42 5 3020 26 2 false 9.792941539016166E-4 9.792941539016166E-4 1.1070924240418437E-179 protein_targeting_to_ER GO:0045047 12133 104 42 6 721 10 3 false 0.0010128663461603984 0.0010128663461603984 1.514347826459292E-128 membrane-enclosed_lumen GO:0031974 12133 3005 42 21 10701 41 1 false 0.001429140653256438 0.001429140653256438 0.0 protein_targeting GO:0006605 12133 443 42 8 2378 14 2 false 0.001429704142902502 0.001429704142902502 0.0 cellular_metabolic_process GO:0044237 12133 7256 42 37 10007 40 2 false 0.0017090463705165537 0.0017090463705165537 0.0 RNA_binding GO:0003723 12133 763 42 14 2849 25 1 false 0.001812032559582025 0.001812032559582025 0.0 nucleus GO:0005634 12133 4764 42 31 7259 35 1 false 0.001968518773481567 0.001968518773481567 0.0 death GO:0016265 12133 1528 42 14 8052 34 1 false 0.0022686030711495777 0.0022686030711495777 0.0 regulation_of_cell_death GO:0010941 12133 1062 42 11 6437 27 2 false 0.0023490744773922495 0.0023490744773922495 0.0 gene_expression GO:0010467 12133 3708 42 31 6052 37 1 false 0.0026884542715254474 0.0026884542715254474 0.0 biosynthetic_process GO:0009058 12133 4179 42 28 8027 37 1 false 0.002760044283308014 0.002760044283308014 0.0 translesion_synthesis GO:0019985 12133 9 42 2 273 3 2 false 0.002858764851384279 0.002858764851384279 4.922351021851153E-17 structural_constituent_of_ribosome GO:0003735 12133 152 42 6 526 7 1 false 0.0028822095855405355 0.0028822095855405355 1.18011379183299E-136 RNA_metabolic_process GO:0016070 12133 3294 42 30 5627 37 2 false 0.003178025732137453 0.003178025732137453 0.0 receptor_tyrosine_kinase_binding GO:0030971 12133 31 42 2 918 3 1 false 0.00324435028631014 0.00324435028631014 1.9469822979582718E-58 negative_regulation_of_cell_morphogenesis_involved_in_differentiation GO:0010771 12133 20 42 2 822 4 4 false 0.0032803561683274543 0.0032803561683274543 1.5483743712673206E-40 heterocyclic_compound_binding GO:1901363 12133 4359 42 29 8962 41 1 false 0.0034020496848794516 0.0034020496848794516 0.0 SCF_complex_assembly GO:0010265 12133 1 42 1 284 1 1 false 0.0035211267605635955 0.0035211267605635955 0.0035211267605635955 nitrogen_compound_metabolic_process GO:0006807 12133 5244 42 32 8027 37 1 false 0.0035395636892295397 0.0035395636892295397 0.0 macromolecular_complex_subunit_organization GO:0043933 12133 1256 42 14 3745 22 1 false 0.0036264983563710903 0.0036264983563710903 0.0 cellular_component_disassembly GO:0022411 12133 351 42 6 7663 34 2 false 0.004004635897637475 0.004004635897637475 0.0 response_to_fluid_shear_stress GO:0034405 12133 21 42 2 2540 12 1 false 0.004088844984045102 0.004088844984045102 1.749198470426598E-52 intracellular_organelle GO:0043229 12133 7958 42 41 9096 41 2 false 0.004116008397873967 0.004116008397873967 0.0 organic_cyclic_compound_binding GO:0097159 12133 4407 42 29 8962 41 1 false 0.004171158395995605 0.004171158395995605 0.0 cell_death GO:0008219 12133 1525 42 14 7542 34 2 false 0.004194842649606722 0.004194842649606722 0.0 reproduction GO:0000003 12133 1345 42 12 10446 41 1 false 0.004322056809200406 0.004322056809200406 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 42 32 7341 37 5 false 0.004384055741283905 0.004384055741283905 0.0 PCNA_complex GO:0043626 12133 1 42 1 9248 41 2 false 0.004433391003409335 0.004433391003409335 1.081314878885772E-4 diadenosine_polyphosphate_metabolic_process GO:0015959 12133 3 42 1 1317 2 1 false 0.0045523467953561235 0.0045523467953561235 2.632593673672407E-9 DNA_polymerase_processivity_factor_activity GO:0030337 12133 1 42 1 1517 7 2 false 0.00461437046803261 0.00461437046803261 6.591957811473036E-4 structural_molecule_activity GO:0005198 12133 526 42 7 10257 42 1 false 0.005059121114042302 0.005059121114042302 0.0 postreplication_repair GO:0006301 12133 16 42 2 368 3 1 false 0.0051951734411081725 0.0051951734411081725 2.574562678585272E-28 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 42 13 2643 15 1 false 0.005208844762477344 0.005208844762477344 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 42 6 516 9 1 false 0.0053129434864347905 0.0053129434864347905 8.917305549619806E-119 sperm_entry GO:0035037 12133 1 42 1 2708 16 4 false 0.00590841949778987 0.00590841949778987 3.692762186116122E-4 translational_termination GO:0006415 12133 92 42 6 513 11 2 false 0.006129963743889809 0.006129963743889809 3.4634519853301643E-104 cellular_protein_localization GO:0034613 12133 914 42 11 1438 11 2 false 0.006690789161849351 0.006690789161849351 0.0 steroid_hormone_receptor_activity GO:0003707 12133 53 42 2 636 2 2 false 0.006824146981627158 0.006824146981627158 1.0367751219101854E-78 regulation_of_mRNA_stability_involved_in_response_to_stress GO:0010610 12133 1 42 1 1147 8 2 false 0.006974716652142065 0.006974716652142065 8.718395815173072E-4 protein_complex_disassembly GO:0043241 12133 154 42 6 1031 13 2 false 0.006996214340253404 0.006996214340253404 4.7545827865276796E-188 mRNA_5'-UTR_binding GO:0048027 12133 5 42 2 91 3 1 false 0.00716137794789482 0.00716137794789482 2.1503314800486076E-8 protein_metabolic_process GO:0019538 12133 3431 42 25 7395 37 2 false 0.007528915594505885 0.007528915594505885 0.0 cytoplasmic_stress_granule GO:0010494 12133 29 42 2 5117 24 2 false 0.007923972298875101 0.007923972298875101 2.627932865737447E-77 spliceosomal_complex GO:0005681 12133 150 42 5 3020 26 2 false 0.007969349869048029 0.007969349869048029 2.455159410572961E-258 cell_communication_by_chemical_coupling GO:0010643 12133 2 42 1 3962 16 1 false 0.00806143595155831 0.00806143595155831 1.2744144352388504E-7 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 42 32 7451 37 1 false 0.008179159605957269 0.008179159605957269 0.0 reproductive_process GO:0022414 12133 1275 42 11 10446 41 2 false 0.008393721148904036 0.008393721148904036 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 42 28 7470 37 2 false 0.008610640366686951 0.008610640366686951 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 42 32 7256 37 1 false 0.008886586845711083 0.008886586845711083 0.0 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 42 23 10446 41 1 false 0.008909111333745733 0.008909111333745733 0.0 nucleic_acid_binding GO:0003676 12133 2849 42 25 4407 29 2 false 0.008992920259501734 0.008992920259501734 0.0 macromolecular_complex_disassembly GO:0032984 12133 199 42 6 1380 14 2 false 0.009148497877452148 0.009148497877452148 1.9082717261040364E-246 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 42 32 7256 37 1 false 0.009176345747705667 0.009176345747705667 0.0 positive_regulation_of_deoxyribonuclease_activity GO:0032077 12133 1 42 1 97 1 3 false 0.01030927835051539 0.01030927835051539 0.01030927835051539 cellular_biosynthetic_process GO:0044249 12133 4077 42 28 7290 37 2 false 0.010393879961771994 0.010393879961771994 0.0 intracellular_transport GO:0046907 12133 1148 42 11 2815 15 2 false 0.010882354458415048 0.010882354458415048 0.0 PCNA-p21_complex GO:0070557 12133 2 42 1 4399 26 2 false 0.011787271095227847 0.011787271095227847 1.0337625825683637E-7 negative_regulation_of_nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:2000623 12133 1 42 1 916 11 4 false 0.012008733624442124 0.012008733624442124 0.0010917030567683713 positive_regulation_of_mitochondrion_organization GO:0010822 12133 43 42 2 385 2 3 false 0.01221590909090837 0.01221590909090837 4.6200993055738E-58 diadenosine_polyphosphate_biosynthetic_process GO:0015960 12133 2 42 1 323 2 2 false 0.01236467126896491 0.01236467126896491 1.9229659827317125E-5 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 42 7 374 7 2 false 0.012771584887865001 0.012771584887865001 2.0954491420584897E-111 cellular_macromolecule_localization GO:0070727 12133 918 42 11 2206 15 2 false 0.012910230685906503 0.012910230685906503 0.0 regulation_of_epithelial_to_mesenchymal_transition GO:0010717 12133 37 42 2 975 5 4 false 0.013043372472454011 0.013043372472454011 7.014478245035562E-68 protein_insertion_into_mitochondrial_membrane GO:0051204 12133 25 42 2 1644 12 4 false 0.01335197017141359 0.01335197017141359 7.460154269678152E-56 multi-organism_process GO:0051704 12133 1180 42 10 10446 41 1 false 0.013819071831975645 0.013819071831975645 0.0 negative_regulation_of_catalytic_activity GO:0043086 12133 588 42 6 4970 18 3 false 0.014206197181688526 0.014206197181688526 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 42 24 7980 41 1 false 0.014324930128840658 0.014324930128840658 0.0 multi-organism_reproductive_process GO:0044703 12133 707 42 10 1275 11 1 false 0.014664697659050306 0.014664697659050306 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 42 24 7958 41 2 false 0.014875184479525157 0.014875184479525157 0.0 lysophospholipid_acyltransferase_activity GO:0071617 12133 1 42 1 131 2 1 false 0.01526717557251871 0.01526717557251871 0.007633587786259341 Cdc48p-Npl4p-Ufd1p_AAA_ATPase_complex GO:0034098 12133 4 42 1 5141 20 4 false 0.015475093400744913 0.015475093400744913 3.439757301821322E-14 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 42 32 7275 37 2 false 0.01564566691797693 0.01564566691797693 0.0 peptidyl-serine_phosphorylation GO:0018105 12133 121 42 3 1201 6 2 false 0.015903774137926777 0.015903774137926777 1.0029038835537004E-169 regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900739 12133 24 42 2 315 3 3 false 0.015957967403806332 0.015957967403806332 1.6734366655590734E-36 mRNA_catabolic_process GO:0006402 12133 181 42 9 592 15 2 false 0.01614504831768548 0.01614504831768548 1.4563864024176219E-157 amino_acid_activation GO:0043038 12133 44 42 2 337 2 1 false 0.016709057510245345 0.016709057510245345 3.048791381604643E-56 histone_serine_kinase_activity GO:0035174 12133 3 42 1 710 4 3 false 0.01682996066330867 0.01682996066330867 1.6835011166660507E-8 protein_targeting_to_membrane GO:0006612 12133 145 42 6 443 8 1 false 0.017008620385434173 0.017008620385434173 5.648405296311656E-121 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 42 3 599 3 2 false 0.017413043295882565 0.017413043295882565 1.7219296535416308E-148 macromolecule_localization GO:0033036 12133 1642 42 14 3467 19 1 false 0.018260346745368562 0.018260346745368562 0.0 RNA_processing GO:0006396 12133 601 42 10 3762 31 2 false 0.01843691894093695 0.01843691894093695 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 42 2 3208 17 2 false 0.01920003178841835 0.01920003178841835 7.591030632914061E-95 pre-B_cell_allelic_exclusion GO:0002331 12133 3 42 1 2936 19 2 false 0.01929533414656717 0.01929533414656717 2.373159805606177E-10 cellular_localization GO:0051641 12133 1845 42 14 7707 34 2 false 0.019349358760220998 0.019349358760220998 0.0 DNA-dependent_transcription,_initiation GO:0006352 12133 225 42 5 2751 20 2 false 0.019590848966875345 0.019590848966875345 0.0 prostate_gland_growth GO:0060736 12133 10 42 1 498 1 3 false 0.020080321285142907 0.020080321285142907 4.236088489692508E-21 regulation_of_protein_complex_assembly GO:0043254 12133 185 42 4 1610 10 3 false 0.02028859879112104 0.02028859879112104 1.34790682725651E-248 intracellular_part GO:0044424 12133 9083 42 41 9983 41 2 false 0.020613570307249234 0.020613570307249234 0.0 positive_regulation_of_RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0045899 12133 2 42 1 1043 11 4 false 0.02099178694265062 0.02099178694265062 1.8402548384908118E-6 positive_regulation_of_cell_death GO:0010942 12133 383 42 6 3330 20 3 false 0.021146290443104468 0.021146290443104468 0.0 negative_regulation_of_epithelial_to_mesenchymal_transition GO:0010719 12133 12 42 2 79 2 3 false 0.021421616358324604 0.021421616358324604 1.9527570787405553E-14 DNA-dependent_protein_kinase_activity GO:0004677 12133 4 42 1 709 4 1 false 0.022423831880911543 0.022423831880911543 9.578723432074247E-11 molecular_function GO:0003674 12133 10257 42 42 11221 42 1 false 0.02282386919970995 0.02282386919970995 0.0 regulation_of_mitochondrial_outer_membrane_permeabilization GO:1901028 12133 33 42 2 354 3 4 false 0.023863254429345972 0.023863254429345972 3.0911895026883726E-47 binding GO:0005488 12133 8962 42 41 10257 42 1 false 0.02420666983081707 0.02420666983081707 0.0 mitochondrial_membrane_organization GO:0007006 12133 62 42 2 924 4 2 false 0.02435400549136059 0.02435400549136059 3.431124286579491E-98 small_conjugating_protein_ligase_binding GO:0044389 12133 147 42 3 1005 5 1 false 0.0244996120627892 0.0244996120627892 6.302468729220369E-181 metabolic_process GO:0008152 12133 8027 42 37 10446 41 1 false 0.02458149264622184 0.02458149264622184 0.0 regulation_of_mitochondrion_organization GO:0010821 12133 64 42 2 661 3 2 false 0.025987537745826263 0.025987537745826263 9.542606350434685E-91 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 42 5 1384 13 2 false 0.02607677392449551 0.02607677392449551 1.3395090025049634E-243 primary_metabolic_process GO:0044238 12133 7288 42 37 8027 37 1 false 0.027821035199747258 0.027821035199747258 0.0 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 42 3 1130 5 2 false 0.02783813743683911 0.02783813743683911 2.620015602340521E-209 DNA_damage_induced_protein_phosphorylation GO:0006975 12133 6 42 1 1649 8 2 false 0.028800946903397184 0.028800946903397184 3.613794793797479E-17 death-inducing_signaling_complex GO:0031264 12133 6 42 1 3798 19 2 false 0.02966218414552045 0.02966218414552045 2.4083454718853365E-19 viral_genome_expression GO:0019080 12133 153 42 6 557 10 2 false 0.029964967148050123 0.029964967148050123 1.6461772406083414E-141 apoptotic_signaling_pathway GO:0097190 12133 305 42 4 3954 16 2 false 0.030081463934107697 0.030081463934107697 0.0 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 42 1 6481 33 2 false 0.030176067895662143 0.030176067895662143 9.738359623180132E-21 catalytic_step_2_spliceosome GO:0071013 12133 76 42 5 151 5 3 false 0.030194539258435526 0.030194539258435526 5.422089502503699E-45 N-terminal_peptidyl-lysine_acetylation GO:0018076 12133 4 42 1 131 1 2 false 0.03053435114503736 0.03053435114503736 8.534870065137808E-8 localization_within_membrane GO:0051668 12133 37 42 2 1845 14 1 false 0.030608014417431363 0.030608014417431363 2.8489513256034824E-78 intracellular GO:0005622 12133 9171 42 41 9983 41 1 false 0.03063466242315679 0.03063466242315679 0.0 regulation_of_RNA_stability GO:0043487 12133 37 42 2 2240 17 2 false 0.03089921326070226 0.03089921326070226 2.0388833014238124E-81 ligase_activity GO:0016874 12133 504 42 5 4901 18 1 false 0.031126430637937866 0.031126430637937866 0.0 regulation_of_response_to_reactive_oxygen_species GO:1901031 12133 8 42 1 755 3 2 false 0.03149374851148717 0.03149374851148717 3.9637366579245895E-19 protein_insertion_into_membrane GO:0051205 12133 32 42 2 1452 13 3 false 0.03155306608115824 0.03155306608115824 2.4360077014496946E-66 germ-line_stem_cell_maintenance GO:0030718 12133 3 42 1 93 1 1 false 0.03225806451612856 0.03225806451612856 7.706178814172994E-6 viral_reproductive_process GO:0022415 12133 557 42 10 783 10 2 false 0.032412126507206464 0.032412126507206464 1.4346997744229993E-203 single-stranded_RNA_binding GO:0003727 12133 40 42 3 763 14 1 false 0.0324999099873117 0.0324999099873117 1.1547828689277465E-67 glucocorticoid_receptor_activity GO:0004883 12133 1 42 1 61 2 3 false 0.03278688524590208 0.03278688524590208 0.016393442622951008 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 42 2 1199 10 2 false 0.03390882647561764 0.03390882647561764 9.194442294553035E-70 regulation_of_glucocorticoid_metabolic_process GO:0031943 12133 7 42 1 3984 20 4 false 0.03464144453971269 0.03464144453971269 3.1804287963038033E-22 protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:0001844 12133 25 42 2 305 4 3 false 0.0350042818165589 0.0350042818165589 3.3284741778861134E-37 cellular_protein_metabolic_process GO:0044267 12133 3038 42 25 5899 37 2 false 0.035175278909433116 0.035175278909433116 0.0 small_protein_activating_enzyme_activity GO:0008641 12133 10 42 1 4901 18 1 false 0.036158771679317706 0.036158771679317706 4.580429379813267E-31 positive_regulation_of_signal_transduction_by_p53_class_mediator GO:1901798 12133 11 42 1 881 3 3 false 0.03703323480531765 0.03703323480531765 1.712543759931694E-25 sarcoplasmic_reticulum_lumen GO:0033018 12133 6 42 1 161 1 2 false 0.03726708074534209 0.03726708074534209 4.5426384829177606E-11 DNA_replication_factor_C_complex GO:0005663 12133 6 42 1 3160 20 3 false 0.037408002848972555 0.037408002848972555 7.265620705764964E-19 epithelial_to_mesenchymal_transition GO:0001837 12133 71 42 2 607 3 2 false 0.03745180568679713 0.03745180568679713 1.494030072752519E-94 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 42 4 6813 27 2 false 0.037837880022410716 0.037837880022410716 0.0 mitotic_nuclear_envelope_reassembly GO:0007084 12133 8 42 1 1043 5 3 false 0.03783860220946844 0.03783860220946844 2.957556257561267E-20 negative_regulation_of_phosphate_metabolic_process GO:0045936 12133 278 42 3 2776 8 3 false 0.03800196715490232 0.03800196715490232 0.0 proteasomal_ubiquitin-independent_protein_catabolic_process GO:0010499 12133 3 42 1 231 3 1 false 0.03862274046438957 0.03862274046438957 4.931464965639191E-7 positive_regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902110 12133 37 42 2 1374 12 3 false 0.03930565048528179 0.03930565048528179 1.7604614397711276E-73 pseudopodium GO:0031143 12133 13 42 1 976 3 1 false 0.03946906453027423 0.03946906453027423 9.253153669613935E-30 regulation_of_deoxyribonuclease_activity GO:0032070 12133 4 42 1 99 1 2 false 0.040404040404039644 0.040404040404039644 2.6564827743029676E-7 profilin_binding GO:0005522 12133 8 42 1 6397 33 1 false 0.040553645153220096 0.040553645153220096 1.4441469602605516E-26 telomere_maintenance GO:0000723 12133 61 42 2 888 5 3 false 0.040577335625961206 0.040577335625961206 5.866244325488287E-96 insulin-like_growth_factor_receptor_binding GO:0005159 12133 13 42 1 918 3 1 false 0.04192993796960486 0.04192993796960486 2.0625046407641684E-29 endothelial_cell_chemotaxis GO:0035767 12133 9 42 1 211 1 2 false 0.04265402843601879 0.04265402843601879 5.203960956600414E-16 regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902108 12133 39 42 2 1375 12 3 false 0.04325206396001238 0.04325206396001238 1.4191902379759833E-76 catenin_complex GO:0016342 12133 7 42 1 3002 19 2 false 0.04351408393575141 0.04351408393575141 2.309914750469473E-21 hormone-mediated_signaling_pathway GO:0009755 12133 81 42 2 3587 15 2 false 0.043723510288632944 0.043723510288632944 1.6796576112410598E-167 regulation_of_cellular_component_organization GO:0051128 12133 1152 42 9 7336 31 2 false 0.04379876458098078 0.04379876458098078 0.0 negative_regulation_of_phosphorylation GO:0042326 12133 215 42 3 1463 6 3 false 0.04450593774574067 0.04450593774574067 2.1310280163327356E-264 cellular_response_to_steroid_hormone_stimulus GO:0071383 12133 91 42 2 706 3 4 false 0.045203690664701326 0.045203690664701326 3.3411431818141285E-117 regulation_of_signaling GO:0023051 12133 1793 42 11 6715 25 2 false 0.046286960259013854 0.046286960259013854 0.0 negative_regulation_of_cysteine-type_endopeptidase_activity GO:2000117 12133 66 42 2 303 2 3 false 0.046882171660867056 0.046882171660867056 1.924144504065005E-68 positive_regulation_of_cellular_process GO:0048522 12133 2811 42 17 9694 40 3 false 0.04691556245038418 0.04691556245038418 0.0 stem_cell_development GO:0048864 12133 191 42 3 1273 6 2 false 0.04696310821408031 0.04696310821408031 5.877761968359015E-233 cell_communication_by_electrical_coupling GO:0010644 12133 12 42 1 3962 16 1 false 0.04746284439612858 0.04746284439612858 3.2554041064980747E-35 glycyl-tRNA_aminoacylation GO:0006426 12133 1 42 1 42 2 1 false 0.04761904761904798 0.04761904761904798 0.023809523809523944 outer_membrane GO:0019867 12133 112 42 2 4398 14 1 false 0.047913979754668705 0.047913979754668705 7.412183245910406E-226 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 42 4 7778 34 4 false 0.04800205455594377 0.04800205455594377 0.0 negative_regulation_of_transcription_by_competitive_promoter_binding GO:0010944 12133 9 42 1 734 4 1 false 0.04824848881086175 0.04824848881086175 6.164271250198973E-21 lipoprotein_catabolic_process GO:0042159 12133 4 42 1 561 7 2 false 0.04911350900937934 0.04911350900937934 2.4491441463337857E-10 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 42 3 1881 12 2 false 0.049264161944670176 0.049264161944670176 3.367676499542027E-210 protein_catabolic_process GO:0030163 12133 498 42 7 3569 25 2 false 0.04948088647439644 0.04948088647439644 0.0 regulation_of_mitochondrial_membrane_permeability GO:0046902 12133 46 42 2 2152 17 3 false 0.04959383839067316 0.04959383839067316 4.367031159968052E-96 ligase_activity,_forming_carbon-oxygen_bonds GO:0016875 12133 39 42 2 504 5 1 false 0.050297086041464 0.050297086041464 3.7172333696305043E-59 RS_domain_binding GO:0050733 12133 5 42 1 486 5 1 false 0.05059707735724379 0.05059707735724379 4.51818185951414E-12 glycine-tRNA_ligase_activity GO:0004820 12133 1 42 1 39 2 1 false 0.051282051282051155 0.051282051282051155 0.02564102564102553 negative_regulation_of_protein_phosphorylation GO:0001933 12133 204 42 3 1311 6 4 false 0.051705915133341517 0.051705915133341517 2.3779440904857207E-245 negative_regulation_of_pathway-restricted_SMAD_protein_phosphorylation GO:0060394 12133 5 42 1 286 3 4 false 0.05171403837082064 0.05171403837082064 6.495558059843893E-11 glucocorticoid_mediated_signaling_pathway GO:0043402 12133 2 42 1 74 2 2 false 0.05368382080710871 0.05368382080710871 3.702332469455773E-4 macromolecule_biosynthetic_process GO:0009059 12133 3475 42 25 6537 37 2 false 0.05398804880274355 0.05398804880274355 0.0 regulation_of_translation GO:0006417 12133 210 42 4 3605 25 4 false 0.05404174085145211 0.05404174085145211 0.0 localization GO:0051179 12133 3467 42 19 10446 41 1 false 0.05450455797339455 0.05450455797339455 0.0 N-terminal_protein_amino_acid_acetylation GO:0006474 12133 8 42 1 146 1 2 false 0.05479452054794698 0.05479452054794698 2.3738367166634384E-13 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 42 3 859 5 3 false 0.05756054767908368 0.05756054767908368 4.662302019201105E-186 cell_part GO:0044464 12133 9983 42 41 10701 41 2 false 0.05766405694856179 0.05766405694856179 0.0 histone_kinase_activity GO:0035173 12133 12 42 1 1016 5 2 false 0.05778767310694843 0.05778767310694843 4.226020118885801E-28 cellular_protein_complex_localization GO:0034629 12133 5 42 1 930 11 2 false 0.057878887160746885 0.057878887160746885 1.7435880605018067E-13 cell GO:0005623 12133 9984 42 41 10701 41 1 false 0.05790183491647689 0.05790183491647689 0.0 nuclear_inner_membrane GO:0005637 12133 23 42 1 397 1 2 false 0.05793450881612017 0.05793450881612017 8.364918311433976E-38 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 42 7 2370 14 1 false 0.05802513266874754 0.05802513266874754 0.0 regulation_of_stem_cell_differentiation GO:2000736 12133 64 42 2 922 6 2 false 0.05934655008199918 0.05934655008199918 2.1519323444963246E-100 intracellular_receptor_signaling_pathway GO:0030522 12133 217 42 3 3547 15 1 false 0.05953541028050213 0.05953541028050213 0.0 nucleotide_biosynthetic_process GO:0009165 12133 322 42 2 1318 2 2 false 0.05954697702390379 0.05954697702390379 2.1862113E-317 regulation_of_cell_communication GO:0010646 12133 1796 42 11 6469 25 2 false 0.05987541802713249 0.05987541802713249 0.0 peptidyl-serine_modification GO:0018209 12133 127 42 3 623 5 1 false 0.06016719610304043 0.06016719610304043 3.781982241942545E-136 membrane_depolarization_involved_in_regulation_of_action_potential GO:0086010 12133 10 42 1 166 1 2 false 0.06024096385542515 0.06024096385542515 3.0110974512264137E-16 positive_regulation_of_hemostasis GO:1900048 12133 17 42 1 825 3 3 false 0.060625121319040125 0.060625121319040125 1.1051628781711435E-35 RNA_splicing GO:0008380 12133 307 42 8 601 10 1 false 0.06114627963695109 0.06114627963695109 4.262015823312228E-180 cellular_response_to_fluid_shear_stress GO:0071498 12133 9 42 1 1133 8 2 false 0.06199556967738306 0.06199556967738306 1.2176648713490337E-22 response_to_hypoxia GO:0001666 12133 200 42 3 2540 12 2 false 0.06226951380054953 0.06226951380054953 2.6634431659671552E-303 regulation_of_nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:2000622 12133 1 42 1 127 8 2 false 0.06299212598425244 0.06299212598425244 0.00787401574803151 organic_substance_metabolic_process GO:0071704 12133 7451 42 37 8027 37 1 false 0.06319369494501688 0.06319369494501688 0.0 regulation_of_peptidyl-serine_phosphorylation GO:0033135 12133 59 42 2 818 6 2 false 0.06356574833501547 0.06356574833501547 1.6613120232447818E-91 negative_regulation_of_tyrosine_phosphorylation_of_STAT_protein GO:0042532 12133 5 42 1 78 1 4 false 0.0641025641025628 0.0641025641025628 4.736846842109758E-8 paraspeckles GO:0042382 12133 6 42 1 272 3 1 false 0.06496153196825426 0.06496153196825426 1.8794561691225117E-12 regulation_of_cell_development GO:0060284 12133 446 42 4 1519 6 2 false 0.06513344477719592 0.06513344477719592 0.0 regulation_of_membrane_depolarization GO:0003254 12133 17 42 1 6307 25 3 false 0.06537071586171155 0.06537071586171155 9.192918420232142E-51 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 42 5 2935 19 1 false 0.06574196649167817 0.06574196649167817 0.0 mitochondrial_outer_membrane GO:0005741 12133 96 42 2 372 2 2 false 0.06608121032953254 0.06608121032953254 1.1824719222700171E-91 telomere_organization GO:0032200 12133 62 42 2 689 5 1 false 0.06672627208199454 0.06672627208199454 5.719891778584196E-90 positive_regulation_of_apoptotic_process GO:0043065 12133 362 42 6 1377 12 3 false 0.0669438827963933 0.0669438827963933 0.0 condensed_chromosome_outer_kinetochore GO:0000940 12133 11 42 1 3160 20 3 false 0.06756199450353528 0.06756199450353528 1.2946879868982565E-31 mitochondrial_outer_membrane_permeabilization GO:0097345 12133 37 42 2 319 4 3 false 0.06765383945361679 0.06765383945361679 2.7662883808425E-49 positive_regulation_of_purine_nucleotide_metabolic_process GO:1900544 12133 82 42 1 1209 1 3 false 0.06782464846982056 0.06782464846982056 1.376514335843937E-129 positive_regulation_of_coagulation GO:0050820 12133 19 42 1 822 3 3 false 0.06783326108728513 0.06783326108728513 6.216723100641454E-39 regulation_of_cellular_response_to_oxidative_stress GO:1900407 12133 8 42 1 346 3 2 false 0.06796495555152242 0.06796495555152242 2.1296766372198142E-16 positive_regulation_of_biological_process GO:0048518 12133 3081 42 17 10446 41 2 false 0.06824423041169783 0.06824423041169783 0.0 transcription_factor_binding GO:0008134 12133 715 42 7 6397 33 1 false 0.0682528951474401 0.0682528951474401 0.0 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 42 6 1393 12 3 false 0.06839547572379547 0.06839547572379547 0.0 intracellular_signal_transduction GO:0035556 12133 1813 42 11 3547 15 1 false 0.06972178817606205 0.06972178817606205 0.0 negative_regulation_of_JAK-STAT_cascade GO:0046426 12133 8 42 1 223 2 3 false 0.07061770290469585 0.07061770290469585 7.485721025490751E-15 transcription_factor_complex GO:0005667 12133 266 42 4 3138 19 2 false 0.0709513414741001 0.0709513414741001 0.0 regulation_of_translational_fidelity GO:0006450 12133 9 42 1 2087 17 2 false 0.07109911745046554 0.07109911745046554 4.915442341416784E-25 negative_regulation_of_cellular_process GO:0048523 12133 2515 42 15 9689 40 3 false 0.07202827169232726 0.07202827169232726 0.0 regulation_of_cell_adhesion GO:0030155 12133 244 42 3 6487 26 2 false 0.07233951007656726 0.07233951007656726 0.0 muscle_organ_morphogenesis GO:0048644 12133 60 42 1 819 1 2 false 0.0732600732600436 0.0732600732600436 1.2170784053074551E-92 response_to_abiotic_stimulus GO:0009628 12133 676 42 5 5200 18 1 false 0.07391655643170869 0.07391655643170869 0.0 phosphatidylinositol_kinase_activity GO:0052742 12133 18 42 1 1181 5 3 false 0.07404043037163534 0.07404043037163534 3.6507847269657347E-40 maintenance_of_location_in_cell GO:0051651 12133 100 42 2 7542 34 3 false 0.07424253783981687 0.07424253783981687 3.2184799576057033E-230 aminoacyl-tRNA_editing_activity GO:0002161 12133 7 42 1 94 1 2 false 0.07446808510638464 0.07446808510638464 9.769567241723248E-11 negative_regulation_of_phosphorus_metabolic_process GO:0010563 12133 278 42 3 3568 13 3 false 0.07462839095462726 0.07462839095462726 0.0 negative_regulation_of_cell_development GO:0010721 12133 106 42 2 1346 6 3 false 0.07476580571407469 0.07476580571407469 1.6785551446261856E-160 regulation_of_mRNA_catabolic_process GO:0061013 12133 11 42 1 3126 22 3 false 0.07486343059435577 0.07486343059435577 1.4585681132963846E-31 regulation_of_protein_catabolic_process GO:0042176 12133 150 42 3 1912 13 3 false 0.07557360313742767 0.07557360313742767 1.3832082048306078E-227 kinase_regulator_activity GO:0019207 12133 125 42 2 1851 7 3 false 0.07595776574015668 0.07595776574015668 5.123060762627793E-198 structure-specific_DNA_binding GO:0043566 12133 179 42 3 2091 12 1 false 0.07629638894313087 0.07629638894313087 1.2928223396172998E-264 negative_regulation_of_molecular_function GO:0044092 12133 735 42 6 10257 42 2 false 0.07691604147869971 0.07691604147869971 0.0 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 42 8 10311 42 3 false 0.07708473878824479 0.07708473878824479 0.0 protein_localization_to_organelle GO:0033365 12133 516 42 9 914 11 1 false 0.07711234492611424 0.07711234492611424 5.634955900168089E-271 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 42 3 201 6 3 false 0.07728214218605857 0.07728214218605857 2.854176062301069E-41 single-organism_transport GO:0044765 12133 2323 42 14 8134 34 2 false 0.07784329696241314 0.07784329696241314 0.0 eukaryotic_translation_initiation_factor_3_complex GO:0005852 12133 16 42 1 6481 33 2 false 0.07851791231817842 0.07851791231817842 2.1998593675926732E-48 positive_regulation_of_cell-cell_adhesion GO:0022409 12133 28 42 1 356 1 3 false 0.07865168539326628 0.07865168539326628 3.28873118060419E-42 regulation_of_signal_transduction GO:0009966 12133 1603 42 10 3826 16 4 false 0.07876224021478344 0.07876224021478344 0.0 protein_kinase_C_inhibitor_activity GO:0008426 12133 3 42 1 38 1 2 false 0.0789473684210529 0.0789473684210529 1.1853959222380309E-4 regulation_of_phosphorylation GO:0042325 12133 845 42 5 1820 6 2 false 0.07901609601149316 0.07901609601149316 0.0 inositol_lipid-mediated_signaling GO:0048017 12133 173 42 3 1813 11 1 false 0.07947247388138964 0.07947247388138964 3.525454591975737E-247 N-terminal_protein_amino_acid_modification GO:0031365 12133 14 42 1 2370 14 1 false 0.07980961217796628 0.07980961217796628 5.136161873069576E-37 positive_regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043517 12133 11 42 1 135 1 4 false 0.08148148148148285 0.08148148148148285 2.2345648964968075E-16 fatty_acid_binding GO:0005504 12133 24 42 1 575 2 2 false 0.08180578700199385 0.08180578700199385 5.916135676713764E-43 protein_phosphatase_type_2A_complex GO:0000159 12133 19 42 1 9083 41 2 false 0.08244637133340572 0.08244637133340572 7.7076041303239345E-59 regulation_of_cellular_response_to_stress GO:0080135 12133 270 42 3 6503 25 3 false 0.08309279959383657 0.08309279959383657 0.0 negative_regulation_of_protein_serine/threonine_kinase_activity GO:0071901 12133 98 42 2 757 4 3 false 0.08356432319172051 0.08356432319172051 4.731915708065017E-126 translation_regulator_activity,_nucleic_acid_binding GO:0090079 12133 10 42 1 2852 25 2 false 0.08440768422598777 0.08440768422598777 1.035447096885048E-28 protein_heterotrimerization GO:0070208 12133 6 42 1 71 1 2 false 0.08450704225352183 0.08450704225352183 6.9823138478995105E-9 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 42 25 6146 37 3 false 0.08564345877504076 0.08564345877504076 0.0 protein_kinase_regulator_activity GO:0019887 12133 106 42 2 1026 5 3 false 0.08591635977655551 0.08591635977655551 2.0818014646962408E-147 transforming_growth_factor_beta_receptor,_cytoplasmic_mediator_activity GO:0005072 12133 10 42 1 339 3 1 false 0.08615783018725402 0.08615783018725402 2.0699598961458892E-19 regulation_of_DNA-dependent_transcription,_initiation GO:2000142 12133 15 42 1 2670 16 3 false 0.0864306536031286 0.0864306536031286 5.444282950561458E-40 organelle_outer_membrane GO:0031968 12133 110 42 2 9084 41 4 false 0.08784823781211831 0.08784823781211831 1.1973077012984011E-257 glucocorticoid_metabolic_process GO:0008211 12133 16 42 1 182 1 1 false 0.08791208791208766 0.08791208791208766 2.8465500356811525E-23 intracellular_protein_transport GO:0006886 12133 658 42 8 1672 13 3 false 0.08860394602236851 0.08860394602236851 0.0 regulation_of_hormone_metabolic_process GO:0032350 12133 20 42 1 4508 21 2 false 0.08933776460237428 0.08933776460237428 2.1124053384021654E-55 immature_B_cell_differentiation GO:0002327 12133 7 42 1 78 1 1 false 0.08974358974358793 0.08974358974358793 3.785151586160923E-10 stem_cell_differentiation GO:0048863 12133 239 42 3 2154 10 1 false 0.08984134195161955 0.08984134195161955 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 42 10 2595 15 2 false 0.08999496702191837 0.08999496702191837 0.0 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0036003 12133 8 42 1 682 8 2 false 0.09052458022296851 0.09052458022296851 8.977212769706076E-19 positive_regulation_of_nuclease_activity GO:0032075 12133 63 42 1 692 1 3 false 0.09104046242772555 0.09104046242772555 4.3142510950266016E-91 embryonic_digit_morphogenesis GO:0042733 12133 37 42 1 406 1 2 false 0.09113300492610615 0.09113300492610615 2.2806113874366256E-53 regulation_of_response_to_stimulus GO:0048583 12133 2074 42 11 7292 26 2 false 0.0912144389313724 0.0912144389313724 0.0 ribosomal_small_subunit_assembly GO:0000028 12133 6 42 1 128 2 3 false 0.09190452755905432 0.09190452755905432 1.8437899825856603E-10 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 42 4 1975 5 1 false 0.09191503631023853 0.09191503631023853 0.0 positive_regulation_of_neuron_death GO:1901216 12133 43 42 2 484 6 3 false 0.0919506616118863 0.0919506616118863 1.4718929225094743E-62 regulation_of_hormone_biosynthetic_process GO:0046885 12133 16 42 1 3001 18 3 false 0.09198928401933609 0.09198928401933609 5.0322201579700966E-43 deacetylase_activity GO:0019213 12133 35 42 1 2556 7 1 false 0.0921076626292691 0.0921076626292691 7.098365746650995E-80 negative_regulation_of_biological_process GO:0048519 12133 2732 42 15 10446 41 2 false 0.09221187917328905 0.09221187917328905 0.0 nuclear_part GO:0044428 12133 2767 42 21 6936 41 2 false 0.09346304865312532 0.09346304865312532 0.0 cytoplasmic_transport GO:0016482 12133 666 42 9 1148 11 1 false 0.09354614621682182 0.09354614621682182 0.0 heart_development GO:0007507 12133 343 42 4 2876 15 3 false 0.09363681335641631 0.09363681335641631 0.0 isoleucyl-tRNA_aminoacylation GO:0006428 12133 2 42 1 42 2 1 false 0.09407665505226606 0.09407665505226606 0.0011614401858304456 RNA_localization GO:0006403 12133 131 42 3 1642 14 1 false 0.09440104774602738 0.09440104774602738 1.0675246049472868E-197 regulation_of_gluconeogenesis GO:0006111 12133 17 42 1 3082 18 5 false 0.09501545237066844 0.09501545237066844 1.8201711110678968E-45 sarcoplasmic_reticulum GO:0016529 12133 42 42 1 858 2 2 false 0.09556021574693375 0.09556021574693375 2.4222927576820215E-72 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 42 10 5558 32 3 false 0.0956652371253745 0.0956652371253745 0.0 negative_regulation_of_peptidyl-threonine_phosphorylation GO:0010801 12133 8 42 1 239 3 3 false 0.09748985129774256 0.09748985129774256 4.263415805054857E-15 positive_regulation_of_neuron_apoptotic_process GO:0043525 12133 42 42 2 457 6 4 false 0.0975761020362099 0.0975761020362099 1.8852854762051817E-60 catabolic_process GO:0009056 12133 2164 42 14 8027 37 1 false 0.09790161889239529 0.09790161889239529 0.0 protein_dimerization_activity GO:0046983 12133 779 42 7 6397 33 1 false 0.0982645821703057 0.0982645821703057 0.0 negative_regulation_of_nuclear_division GO:0051784 12133 43 42 1 436 1 3 false 0.0986238532109988 0.0986238532109988 1.634686522119006E-60 transforming_growth_factor_beta_receptor_binding GO:0005160 12133 17 42 1 172 1 1 false 0.09883720930232588 0.09883720930232588 7.980309943146777E-24 response_to_stress GO:0006950 12133 2540 42 12 5200 18 1 false 0.10005669564576111 0.10005669564576111 0.0 cellular_catabolic_process GO:0044248 12133 1972 42 14 7289 37 2 false 0.10022596693313701 0.10022596693313701 0.0 protein_domain_specific_binding GO:0019904 12133 486 42 5 6397 33 1 false 0.10117289813524671 0.10117289813524671 0.0 isoleucine-tRNA_ligase_activity GO:0004822 12133 2 42 1 39 2 1 false 0.1012145748987855 0.1012145748987855 0.0013495276653171407 negative_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043154 12133 63 42 2 1373 12 3 false 0.10174009727107085 0.10174009727107085 1.783777218833555E-110 mitogen-activated_protein_kinase_kinase_binding GO:0031434 12133 12 42 1 341 3 1 false 0.10218987239356263 0.10218987239356263 2.356690583847287E-22 negative_regulation_of_endopeptidase_activity GO:0010951 12133 152 42 2 474 2 3 false 0.10237196813588902 0.10237196813588902 1.8080345918982332E-128 mammary_gland_epithelium_development GO:0061180 12133 68 42 1 661 1 2 false 0.10287443267775957 0.10287443267775957 1.483146375538298E-94 protein_kinase_C_activity GO:0004697 12133 19 42 1 709 4 1 false 0.10317051060648307 0.10317051060648307 1.067786620182717E-37 positive_regulation_of_nuclear-transcribed_mRNA_catabolic_process,_deadenylation-dependent_decay GO:1900153 12133 6 42 1 58 1 3 false 0.10344827586207023 0.10344827586207023 2.470639049072758E-8 mismatch_repair_complex_binding GO:0032404 12133 11 42 1 306 3 1 false 0.10434218985263097 0.10434218985263097 2.173641584292119E-20 nucleolus GO:0005730 12133 1357 42 13 4208 29 3 false 0.106548880430693 0.106548880430693 0.0 extrinsic_to_membrane GO:0019898 12133 111 42 1 2995 3 1 false 0.10714993342944198 0.10714993342944198 1.8304176420472748E-205 Cul5-RING_ubiquitin_ligase_complex GO:0031466 12133 5 42 1 90 2 1 false 0.10861423220973858 0.10861423220973858 2.2753507521444733E-8 organic_substance_catabolic_process GO:1901575 12133 2054 42 14 7502 37 2 false 0.10861467954360135 0.10861467954360135 0.0 regulation_of_DNA_replication GO:0006275 12133 92 42 2 2913 18 3 false 0.10887890271261194 0.10887890271261194 1.0142928746758388E-176 glucocorticoid_biosynthetic_process GO:0006704 12133 11 42 1 101 1 2 false 0.10891089108910726 0.10891089108910726 6.291677879194737E-15 regulation_of_transcription_initiation_from_RNA_polymerase_II_promoter GO:0060260 12133 13 42 1 1243 11 3 false 0.10963198224438052 0.10963198224438052 3.9219319072235074E-31 cellular_response_to_stress GO:0033554 12133 1124 42 7 4743 18 2 false 0.11049624168487882 0.11049624168487882 0.0 positive_regulation_of_blood_coagulation GO:0030194 12133 17 42 1 445 3 4 false 0.11052338259072704 0.11052338259072704 4.6062559690809185E-31 histone_phosphorylation GO:0016572 12133 21 42 1 1447 8 2 false 0.11062736079434198 0.11062736079434198 2.522509168644094E-47 ribosome_assembly GO:0042255 12133 16 42 1 417 3 3 false 0.11100406051433201 0.11100406051433201 3.349634512578164E-29 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 42 6 220 8 2 false 0.11236487439133892 0.11236487439133892 1.3850176335002185E-65 regulation_of_peptidyl-threonine_phosphorylation GO:0010799 12133 19 42 1 804 5 2 false 0.11297307430479209 0.11297307430479209 9.512945795390505E-39 ribonucleoprotein_granule GO:0035770 12133 75 42 2 3365 26 2 false 0.11306543764264525 0.11306543764264525 1.704323678285534E-155 response_to_superoxide GO:0000303 12133 17 42 1 292 2 2 false 0.11323730169937973 0.11323730169937973 7.010604559669941E-28 translation_activator_activity GO:0008494 12133 6 42 1 52 1 2 false 0.11538461538461588 0.11538461538461588 4.911948412752932E-8 negative_regulation_of_intracellular_protein_kinase_cascade GO:0010741 12133 140 42 2 1142 5 3 false 0.11634571587030251 0.11634571587030251 8.254846485029262E-184 protein_serine/threonine_kinase_inhibitor_activity GO:0030291 12133 22 42 1 724 4 3 false 0.11634849782755796 0.11634849782755796 1.8900653580041414E-42 cell_cycle_phase_transition GO:0044770 12133 415 42 4 953 5 1 false 0.11654597731950708 0.11654597731950708 1.4433288987581492E-282 RNA_polymerase_II_activating_transcription_factor_binding GO:0001102 12133 44 42 2 357 5 2 false 0.11661066477161894 0.11661066477161894 2.031577352129153E-57 protein_deneddylation GO:0000338 12133 9 42 1 77 1 1 false 0.1168831168831165 0.1168831168831165 6.198761061406022E-12 regulation_of_cell_differentiation GO:0045595 12133 872 42 6 6612 26 3 false 0.11797658419235126 0.11797658419235126 0.0 mesenchyme_development GO:0060485 12133 139 42 2 2065 9 2 false 0.11864331966247807 0.11864331966247807 1.8744304993238498E-220 establishment_of_localization GO:0051234 12133 2833 42 15 10446 41 2 false 0.11867803115520162 0.11867803115520162 0.0 positive_regulation_of_protein_oligomerization GO:0032461 12133 15 42 1 363 3 3 false 0.11923018984576098 0.11923018984576098 7.002118429057617E-27 mismatched_DNA_binding GO:0030983 12133 13 42 1 109 1 1 false 0.11926605504587218 0.11926605504587218 4.2768695787200344E-17 cAMP_metabolic_process GO:0046058 12133 143 42 1 1194 1 2 false 0.11976549413740027 0.11976549413740027 2.6525041284959264E-189 cell_cycle_phase GO:0022403 12133 253 42 3 953 5 1 false 0.11994489742655098 0.11994489742655098 1.0384727319913012E-238 mRNA_5'-splice_site_recognition GO:0000395 12133 3 42 1 25 1 2 false 0.12000000000000016 0.12000000000000016 4.347826086956512E-4 innate_immune_response GO:0045087 12133 626 42 3 1268 3 2 false 0.12003540610840648 0.12003540610840648 0.0 regulation_of_cardiac_muscle_cell_membrane_potential GO:0086036 12133 26 42 1 216 1 1 false 0.12037037037037071 0.12037037037037071 3.8960304429291735E-34 negative_regulation_of_B_cell_activation GO:0050869 12133 24 42 1 199 1 3 false 0.12060301507537793 0.12060301507537793 1.7692409305576342E-31 activin_receptor_signaling_pathway GO:0032924 12133 28 42 1 232 1 1 false 0.12068965517240773 0.12068965517240773 9.723452082207629E-37 neurotrophin_signaling_pathway GO:0038179 12133 253 42 2 2018 5 2 false 0.12114277777297655 0.12114277777297655 0.0 negative_regulation_of_tyrosine_phosphorylation_of_Stat3_protein GO:0042518 12133 4 42 1 33 1 3 false 0.12121212121212037 0.12121212121212037 2.4437927663734027E-5 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 42 6 145 6 1 false 0.12300365486559368 0.12300365486559368 1.7288474062512548E-37 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 42 2 1054 7 3 false 0.12303940260286206 0.12303940260286206 5.573854633657796E-137 RNA_polymerase_II_transcription_factor_binding GO:0001085 12133 133 42 3 715 7 1 false 0.12384365199007186 0.12384365199007186 1.758868350294454E-148 negative_regulation_of_cell_death GO:0060548 12133 567 42 6 3054 19 3 false 0.12397520329189157 0.12397520329189157 0.0 nuclear_matrix GO:0016363 12133 81 42 2 2767 21 2 false 0.1242948621067273 0.1242948621067273 2.9785824972298125E-158 regulation_of_programmed_cell_death GO:0043067 12133 1031 42 11 1410 12 2 false 0.12532921606905284 0.12532921606905284 0.0 nuclear_envelope_organization GO:0006998 12133 27 42 1 819 4 2 false 0.12570833343431215 0.12570833343431215 3.6853965573892743E-51 negative_regulation_of_mitosis GO:0045839 12133 43 42 1 656 2 5 false 0.1268944330664553 0.1268944330664553 1.8426541499010044E-68 DNA-dependent_transcriptional_preinitiation_complex_assembly GO:0070897 12133 9 42 1 338 5 2 false 0.12694560491829768 0.12694560491829768 7.01716404793524E-18 pathway-restricted_SMAD_protein_phosphorylation GO:0060389 12133 30 42 1 1331 6 2 false 0.1280686945353398 0.1280686945353398 6.939301694879332E-62 negative_regulation_of_peptidase_activity GO:0010466 12133 156 42 2 695 3 3 false 0.12811422331877956 0.12811422331877956 5.1885244604442586E-160 histone-serine_phosphorylation GO:0035404 12133 6 42 1 135 3 2 false 0.1284080848888441 0.1284080848888441 1.3312318799748158E-10 protein_binding GO:0005515 12133 6397 42 33 8962 41 1 false 0.129575473824518 0.129575473824518 0.0 regulation_of_neurological_system_process GO:0031644 12133 172 42 2 1040 4 2 false 0.1298318690490102 0.1298318690490102 8.112526166227745E-202 single-organism_cellular_process GO:0044763 12133 7541 42 34 9888 40 2 false 0.13009465158088068 0.13009465158088068 0.0 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 42 10 5151 32 4 false 0.13084020844513242 0.13084020844513242 0.0 activin_binding GO:0048185 12133 14 42 1 306 3 1 false 0.13148166945810208 0.13148166945810208 1.8681149729885105E-24 positive_regulation_of_mRNA_catabolic_process GO:0061014 12133 10 42 1 1217 17 4 false 0.13168364183352554 0.13168364183352554 5.28393839702249E-25 nucleotide-excision_repair,_DNA_gap_filling GO:0006297 12133 22 42 1 791 5 2 false 0.13185633449423703 0.13185633449423703 2.6234832277484992E-43 negative_regulation_of_B_cell_proliferation GO:0030889 12133 12 42 1 91 1 4 false 0.13186813186813184 0.13186813186813184 3.169549343553539E-15 regulation_of_system_process GO:0044057 12133 373 42 3 2254 8 2 false 0.13228740013690957 0.13228740013690957 0.0 replicative_senescence GO:0090399 12133 9 42 1 68 1 1 false 0.1323529411764698 0.1323529411764698 2.0292180977540448E-11 regulation_of_activin_receptor_signaling_pathway GO:0032925 12133 19 42 1 143 1 2 false 0.13286713286712723 0.13286713286712723 4.753428687059348E-24 positive_regulation_of_cellular_catabolic_process GO:0031331 12133 106 42 2 3311 20 4 false 0.132896406236091 0.132896406236091 4.802217577498734E-203 response_to_growth_factor_stimulus GO:0070848 12133 545 42 4 1783 7 1 false 0.1330603697732573 0.1330603697732573 0.0 regulation_of_signal_transduction_by_p53_class_mediator GO:1901796 12133 24 42 1 1685 10 2 false 0.13397775230434086 0.13397775230434086 2.665493557536061E-54 mammary_gland_duct_morphogenesis GO:0060603 12133 37 42 1 274 1 3 false 0.13503649635036066 0.13503649635036066 1.1164930078248282E-46 RNA_polymerase_II_core_promoter_proximal_region_sequence-specific_DNA_binding GO:0000978 12133 97 42 2 263 2 2 false 0.13514062636051663 0.13514062636051663 1.2573160822677278E-74 protein_binding_transcription_factor_activity GO:0000988 12133 488 42 4 10311 42 3 false 0.13580195002866036 0.13580195002866036 0.0 regulation_of_apoptotic_process GO:0042981 12133 1019 42 11 1381 12 2 false 0.13595639927603473 0.13595639927603473 0.0 viral_infectious_cycle GO:0019058 12133 213 42 6 557 10 1 false 0.13622173873112114 0.13622173873112114 3.455075709157513E-160 RNA_polymerase_II_core_promoter_proximal_region_sequence-specific_DNA_binding_transcription_factor_activity GO:0000982 12133 86 42 2 232 2 2 false 0.13640095536645602 0.13640095536645602 6.846294333328683E-66 phospholipid_metabolic_process GO:0006644 12133 222 42 2 3035 9 3 false 0.136481366359284 0.136481366359284 0.0 sprouting_angiogenesis GO:0002040 12133 41 42 1 300 1 1 false 0.136666666666661 0.136666666666661 1.6101766178150428E-51 regulation_of_protein_autophosphorylation GO:0031952 12133 21 42 1 870 6 2 false 0.13673403216382551 0.13673403216382551 1.2136753132364896E-42 regulation_of_nuclear-transcribed_mRNA_catabolic_process,_deadenylation-dependent_decay GO:1900151 12133 8 42 1 58 1 2 false 0.13793103448276028 0.13793103448276028 5.217035699399583E-10 ubiquitin_ligase_complex GO:0000151 12133 147 42 2 9248 41 2 false 0.13796529583728026 0.13796529583728026 0.0 sphingolipid_metabolic_process GO:0006665 12133 68 42 1 1861 4 2 false 0.13844601619740293 0.13844601619740293 3.889189985048589E-126 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 42 8 1546 13 3 false 0.13962372049052554 0.13962372049052554 0.0 regulation_of_synaptic_plasticity GO:0048167 12133 82 42 2 2092 17 2 false 0.14129372380153574 0.14129372380153574 1.2289450112441968E-149 regulation_of_pathway-restricted_SMAD_protein_phosphorylation GO:0060393 12133 26 42 1 867 5 3 false 0.14152216984833632 0.14152216984833632 2.407355620871874E-50 adrenal_gland_development GO:0030325 12133 21 42 1 284 2 2 false 0.14266162345094516 0.14266162345094516 3.294656869413388E-32 lysophosphatidic_acid_acyltransferase_activity GO:0042171 12133 1 42 1 7 1 2 false 0.14285714285714285 0.14285714285714285 0.14285714285714285 MAP_kinase_kinase_kinase_activity GO:0004709 12133 26 42 1 520 3 3 false 0.1428861561808948 0.1428861561808948 1.8429565665115438E-44 establishment_of_localization_in_cell GO:0051649 12133 1633 42 12 2978 17 2 false 0.14324497673075973 0.14324497673075973 0.0 small_molecule_binding GO:0036094 12133 2102 42 13 8962 41 1 false 0.14386298952420312 0.14386298952420312 0.0 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 42 8 174 9 1 false 0.1443642576062112 0.1443642576062112 2.5039480990851377E-47 protein_serine/threonine_phosphatase_complex GO:0008287 12133 38 42 1 10006 41 2 false 0.14471133908716885 0.14471133908716885 5.4849454028851035E-108 cardiovascular_system_development GO:0072358 12133 655 42 5 2686 12 2 false 0.14473490546795537 0.14473490546795537 0.0 circulatory_system_development GO:0072359 12133 655 42 5 2686 12 1 false 0.14473490546795537 0.14473490546795537 0.0 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 42 5 742 6 2 false 0.14475630470676554 0.14475630470676554 9.121396596563632E-222 smoothened_signaling_pathway GO:0007224 12133 61 42 1 1975 5 1 false 0.14531914208355648 0.14531914208355648 1.2091892042271557E-117 TBP-class_protein_binding GO:0017025 12133 16 42 1 715 7 1 false 0.14708811920861942 0.14708811920861942 5.310604856356121E-33 protein_trimerization GO:0070206 12133 22 42 1 288 2 1 false 0.14718834688344318 0.14718834688344318 2.002068954416936E-33 regulation_of_removal_of_superoxide_radicals GO:2000121 12133 4 42 1 27 1 4 false 0.1481481481481481 0.1481481481481481 5.6980056980056985E-5 maturation_of_SSU-rRNA GO:0030490 12133 8 42 1 104 2 2 false 0.14861837191933652 0.14861837191933652 3.8823564737710265E-12 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 42 8 2877 17 6 false 0.14949388748256698 0.14949388748256698 0.0 transferase_activity,_transferring_acyl_groups GO:0016746 12133 156 42 2 1779 8 1 false 0.15079356066685953 0.15079356066685953 7.715087379917376E-229 regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043516 12133 24 42 1 158 1 3 false 0.15189873417722227 0.15189873417722227 6.672081748801047E-29 ribonucleoprotein_complex_assembly GO:0022618 12133 117 42 2 646 4 3 false 0.1519967411022734 0.1519967411022734 4.631331466925404E-132 regulation_of_transcription_involved_in_G1/S_phase_of_mitotic_cell_cycle GO:0000083 12133 23 42 1 1971 14 3 false 0.1520021343014663 0.1520021343014663 4.905259542985714E-54 cellular_response_to_gamma_radiation GO:0071480 12133 9 42 1 59 1 2 false 0.15254237288135503 0.15254237288135503 7.958190049931479E-11 establishment_of_RNA_localization GO:0051236 12133 124 42 2 2839 16 2 false 0.15261133818118203 0.15261133818118203 1.4765023034812589E-220 apoptotic_mitochondrial_changes GO:0008637 12133 87 42 2 1476 12 2 false 0.15454076176535766 0.15454076176535766 5.447605955370739E-143 NF-kappaB_import_into_nucleus GO:0042348 12133 34 42 1 220 1 2 false 0.15454545454545285 0.15454545454545285 9.912199511410154E-41 striated_muscle_contraction GO:0006941 12133 87 42 2 220 2 1 false 0.15529265255291755 0.15529265255291755 1.3725907999420383E-63 single-organism_developmental_process GO:0044767 12133 2776 42 15 8064 34 2 false 0.15591226064307356 0.15591226064307356 0.0 positive_regulation_of_lyase_activity GO:0051349 12133 64 42 1 1165 3 3 false 0.1560454165372232 0.1560454165372232 4.208539259642897E-107 negative_regulation_of_kinase_activity GO:0033673 12133 172 42 2 1181 5 3 false 0.15648944288099273 0.15648944288099273 3.9159843646516213E-212 core_promoter_proximal_region_DNA_binding GO:0001159 12133 105 42 2 1169 8 1 false 0.1567077517108062 0.1567077517108062 1.0120474547123083E-152 regulation_of_protein_phosphorylation GO:0001932 12133 787 42 5 1444 6 3 false 0.156952629947486 0.156952629947486 0.0 extrinsic_to_plasma_membrane GO:0019897 12133 76 42 1 1352 3 2 false 0.15944820867097814 0.15944820867097814 1.795634708335668E-126 establishment_of_protein_localization GO:0045184 12133 1153 42 9 3010 17 2 false 0.15981794458705345 0.15981794458705345 0.0 positive_regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014068 12133 45 42 1 798 3 3 false 0.16000157199610768 0.16000157199610768 1.088358768929943E-74 phosphorylation GO:0016310 12133 1421 42 6 2776 8 1 false 0.16033337081624674 0.16033337081624674 0.0 mismatch_repair GO:0006298 12133 21 42 1 368 3 1 false 0.16202762764104384 0.16202762764104384 1.1970307087033421E-34 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 42 1 222 1 3 false 0.1621621621621573 0.1621621621621573 2.5456303013282065E-42 phosphatidic_acid_metabolic_process GO:0046473 12133 16 42 1 189 2 1 false 0.16255769447256882 0.16255769447256882 1.516477657108359E-23 cellular_response_to_organic_cyclic_compound GO:0071407 12133 190 42 2 1540 6 2 false 0.1626914616309606 0.1626914616309606 4.3845861432353096E-249 regulation_of_mitosis GO:0007088 12133 100 42 1 611 1 4 false 0.16366612111294565 0.16366612111294565 1.2375244614825155E-117 response_to_cadmium_ion GO:0046686 12133 31 42 1 189 1 1 false 0.16402116402115946 0.16402116402115946 2.9910568629956633E-36 gap_junction GO:0005921 12133 19 42 1 222 2 1 false 0.16420039949449894 0.16420039949449894 7.056867054521962E-28 actomyosin GO:0042641 12133 50 42 1 1139 4 2 false 0.16456750755636815 0.16456750755636815 1.3517358507370187E-88 maintenance_of_protein_location GO:0045185 12133 100 42 2 1490 11 2 false 0.16530561688025092 0.16530561688025092 1.3409119998512189E-158 core_promoter_proximal_region_sequence-specific_DNA_binding GO:0000987 12133 104 42 2 1120 8 2 false 0.16545169786991487 0.16545169786991487 1.0916537651149318E-149 organelle_organization GO:0006996 12133 2031 42 12 7663 34 2 false 0.16549759526506835 0.16549759526506835 0.0 regulation_of_developmental_process GO:0050793 12133 1233 42 7 7209 27 2 false 0.16566964531816256 0.16566964531816256 0.0 positive_regulation_of_reactive_oxygen_species_metabolic_process GO:2000379 12133 30 42 1 1841 11 3 false 0.16575133017508328 0.16575133017508328 3.7602443852481856E-66 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 42 23 5597 34 2 false 0.16582190668565808 0.16582190668565808 0.0 cellular_response_to_tumor_necrosis_factor GO:0071356 12133 66 42 1 397 1 2 false 0.16624685138538736 0.16624685138538736 5.047562099281639E-77 nuclear_periphery GO:0034399 12133 97 42 2 2767 21 2 false 0.1663385353720342 0.1663385353720342 7.041791399430774E-182 protein_complex_subunit_organization GO:0071822 12133 989 42 13 1256 14 1 false 0.16682779346862442 0.16682779346862442 2.2763776011987297E-281 chromatin_binding GO:0003682 12133 309 42 3 8962 41 1 false 0.16690271234633125 0.16690271234633125 0.0 positive_regulation_of_cyclase_activity GO:0031281 12133 63 42 1 1064 3 3 false 0.167469493287751 0.167469493287751 2.5891490792503797E-103 multicellular_organismal_development GO:0007275 12133 3069 42 15 4373 18 2 false 0.16809546871809958 0.16809546871809958 0.0 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 42 10 4582 28 3 false 0.16813511987038576 0.16813511987038576 0.0 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 42 4 1356 6 2 false 0.16825406832426326 0.16825406832426326 0.0 cellular_response_to_vascular_endothelial_growth_factor_stimulus GO:0035924 12133 24 42 1 532 4 1 false 0.16904812607854175 0.16904812607854175 3.9767651939394526E-42 corticosteroid_receptor_signaling_pathway GO:0031958 12133 9 42 1 102 2 1 false 0.16948165404775553 0.16948165404775553 4.366020704126167E-13 phosphatidylinositol_3-kinase_activity GO:0035004 12133 43 42 1 1178 5 2 false 0.1699336293799611 0.1699336293799611 1.1452136778461344E-79 heterocycle_biosynthetic_process GO:0018130 12133 3248 42 23 5588 34 2 false 0.17018074339422257 0.17018074339422257 0.0 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 42 1 953 5 4 false 0.17096169605528005 0.17096169605528005 1.0482452124052062E-64 cysteine-type_endopeptidase_activity GO:0004197 12133 219 42 2 527 2 2 false 0.17222819460181882 0.17222819460181882 1.229090165658057E-154 RNA_polymerase_II_transcription_factor_binding_transcription_factor_activity_involved_in_negative_regulation_of_transcription GO:0001191 12133 24 42 1 521 4 2 false 0.17237799636024845 0.17237799636024845 6.640599439430319E-42 regulation_of_NF-kappaB_import_into_nucleus GO:0042345 12133 34 42 1 197 1 3 false 0.17258883248730078 0.17258883248730078 5.91301474468331E-39 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 42 23 5686 34 2 false 0.1728569945085788 0.1728569945085788 0.0 synaptic_transmission GO:0007268 12133 515 42 3 923 3 2 false 0.17325886333078988 0.17325886333078988 2.6714189194289816E-274 signalosome GO:0008180 12133 32 42 1 4399 26 2 false 0.17334566500129667 0.17334566500129667 7.6195658646057E-82 mitochondrial_transport GO:0006839 12133 124 42 2 2454 15 2 false 0.17348749515175044 0.17348749515175044 1.607876790046367E-212 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 42 3 200 6 3 false 0.1744310455761188 0.1744310455761188 7.491323649368413E-49 collagen_binding GO:0005518 12133 37 42 1 6397 33 1 false 0.17461610045201328 0.17461610045201328 2.3062856812384995E-98 lymphocyte_differentiation GO:0030098 12133 203 42 2 485 2 2 false 0.17468688762034476 0.17468688762034476 1.747932496277033E-142 cellular_response_to_hormone_stimulus GO:0032870 12133 384 42 3 1510 6 3 false 0.17591257625483878 0.17591257625483878 0.0 tRNA_aminoacylation GO:0043039 12133 44 42 2 104 2 2 false 0.17662434652725223 0.17662434652725223 2.147723813188652E-30 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 42 2 2191 15 3 false 0.17664503952373334 0.17664503952373334 2.495063769189982E-191 response_to_osmotic_stress GO:0006970 12133 43 42 1 2681 12 2 false 0.17669462318582374 0.17669462318582374 3.246680302266631E-95 RNA_polymerase_II_transcription_coactivator_activity GO:0001105 12133 20 42 1 836 8 5 false 0.17678672731104045 0.17678672731104045 1.1002182910399087E-40 response_to_tumor_necrosis_factor GO:0034612 12133 82 42 1 461 1 1 false 0.17787418655096068 0.17787418655096068 3.844095875136562E-93 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 42 10 4456 28 4 false 0.17878110508424266 0.17878110508424266 0.0 hydrolase_activity,_acting_on_glycosyl_bonds GO:0016798 12133 71 42 1 2556 7 1 false 0.17916345751538992 0.17916345751538992 2.6242805767004584E-140 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 42 23 5629 34 2 false 0.17946909701148783 0.17946909701148783 0.0 positive_regulation_of_catabolic_process GO:0009896 12133 137 42 2 3517 20 3 false 0.18179039307078626 0.18179039307078626 1.0965595914697655E-250 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 42 1 242 1 2 false 0.18181818181816245 0.18181818181816245 2.220259827778367E-49 deoxyribonuclease_activity GO:0004536 12133 36 42 1 197 1 1 false 0.18274111675125865 0.18274111675125865 2.8214794282741635E-40 female_gamete_generation GO:0007292 12133 65 42 1 355 1 1 false 0.18309859154930105 0.18309859154930105 7.344010792750422E-73 cellular_process GO:0009987 12133 9675 42 40 10446 41 1 false 0.18346155598310235 0.18346155598310235 0.0 cytoplasmic_sequestering_of_NF-kappaB GO:0007253 12133 9 42 1 49 1 3 false 0.18367346938775714 0.18367346938775714 4.867469433024523E-10 heart_process GO:0003015 12133 132 42 2 307 2 1 false 0.18407102254579047 0.18407102254579047 1.7124819377000923E-90 heart_contraction GO:0060047 12133 132 42 2 307 2 2 false 0.18407102254579047 0.18407102254579047 1.7124819377000923E-90 response_to_oxygen_levels GO:0070482 12133 214 42 3 676 5 1 false 0.18491303749934163 0.18491303749934163 1.6255941364061853E-182 regulation_of_steroid_metabolic_process GO:0019218 12133 56 42 1 301 1 2 false 0.18604651162788827 0.18604651162788827 2.659882776337694E-62 I-SMAD_binding GO:0070411 12133 11 42 1 59 1 1 false 0.1864406779661002 0.1864406779661002 3.573064920377458E-12 ligand-activated_sequence-specific_DNA_binding_RNA_polymerase_II_transcription_factor_activity GO:0004879 12133 48 42 1 956 4 3 false 0.18648161294505353 0.18648161294505353 3.5732659423949603E-82 regulation_of_superoxide_metabolic_process GO:0090322 12133 14 42 1 75 1 2 false 0.1866666666666661 0.1866666666666661 1.7836158063330226E-15 negative_regulation_of_peptidyl-serine_phosphorylation GO:0033137 12133 12 42 1 298 5 3 false 0.18692425417648087 0.18692425417648087 1.2223329169573227E-21 regulation_of_synaptic_transmission GO:0050804 12133 146 42 2 527 3 2 false 0.18721633630761783 0.18721633630761783 2.2122601830133273E-134 positive_regulation_of_metabolic_process GO:0009893 12133 1872 42 11 8366 37 3 false 0.1875232519108216 0.1875232519108216 0.0 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 42 5 982 5 1 false 0.18860492831538925 0.18860492831538925 2.6984349291053464E-253 RNA_export_from_nucleus GO:0006405 12133 72 42 2 165 2 2 false 0.18891352549889404 0.18891352549889404 1.3059643179360761E-48 NF-kappaB_binding GO:0051059 12133 21 42 1 715 7 1 false 0.1890657635484379 0.1890657635484379 7.883315092172008E-41 cellular_response_to_superoxide GO:0071451 12133 14 42 1 74 1 2 false 0.18918918918918864 0.18918918918918864 2.1929702536881746E-15 RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0051123 12133 8 42 1 196 5 2 false 0.1898769276666523 0.1898769276666523 2.1395419233362556E-14 NuRD_complex GO:0016581 12133 16 42 1 84 1 3 false 0.19047619047619396 0.19047619047619396 1.5656458332033387E-17 regulation_of_smoothened_signaling_pathway GO:0008589 12133 34 42 1 1623 10 2 false 0.19128573968106863 0.19128573968106863 2.9545758187222615E-71 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 42 1 230 1 4 false 0.1913043478260654 0.1913043478260654 2.6271911283291635E-48 protein_C-terminus_binding GO:0008022 12133 157 42 2 6397 33 1 false 0.19369237205352205 0.19369237205352205 2.34014E-319 cardiac_septum_morphogenesis GO:0060411 12133 40 42 1 2812 15 4 false 0.19381664806319468 0.19381664806319468 1.180500620986412E-90 rRNA_processing GO:0006364 12133 102 42 2 231 2 3 false 0.19390175042345975 0.19390175042345975 2.6685808966337758E-68 positive_regulation_of_nuclear-transcribed_mRNA_poly(A)_tail_shortening GO:0060213 12133 7 42 1 36 1 4 false 0.19444444444444467 0.19444444444444467 1.1979376305751926E-7 phosphatidylinositol-3-phosphate_biosynthetic_process GO:0036092 12133 15 42 1 77 1 1 false 0.19480519480519415 0.19480519480519415 2.8345227270842315E-16 kinase_inhibitor_activity GO:0019210 12133 49 42 1 1377 6 4 false 0.19571535791378636 0.19571535791378636 2.2473743885530668E-91 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 42 1 243 3 2 false 0.19628829474170104 0.19628829474170104 1.7559807727942103E-26 regulation_of_cardiac_muscle_cell_action_potential GO:0086001 12133 23 42 1 117 1 2 false 0.19658119658119338 0.19658119658119338 7.080869783203112E-25 regulation_of_transmission_of_nerve_impulse GO:0051969 12133 160 42 2 2127 11 4 false 0.19815450558193687 0.19815450558193687 7.858109974637731E-246 mitotic_cell_cycle GO:0000278 12133 625 42 5 1295 7 1 false 0.1984061757914341 0.1984061757914341 0.0 hormone_biosynthetic_process GO:0042446 12133 33 42 1 4208 28 2 false 0.19841192521989579 0.19841192521989579 2.505074337388623E-83 artery_morphogenesis GO:0048844 12133 39 42 1 373 2 2 false 0.19843466228486933 0.19843466228486933 8.072827424238311E-54 transforming_growth_factor_beta_receptor,_inhibitory_cytoplasmic_mediator_activity GO:0030617 12133 2 42 1 10 1 1 false 0.1999999999999998 0.1999999999999998 0.022222222222222185 positive_regulation_of_mRNA_processing GO:0050685 12133 19 42 1 1291 15 3 false 0.2003841198373472 0.2003841198373472 1.0846695642468986E-42 protein_complex_localization GO:0031503 12133 29 42 1 1434 11 1 false 0.20190721230802738 0.20190721230802738 3.39152835029198E-61 biological_process GO:0008150 12133 10446 42 41 11221 42 1 false 0.20317405369094815 0.20317405369094815 0.0 DNA_replication_preinitiation_complex GO:0031261 12133 28 42 1 877 7 3 false 0.20381869231936922 0.20381869231936922 1.8592053486968803E-53 cardiac_muscle_contraction GO:0060048 12133 68 42 2 150 2 2 false 0.20384787472035815 0.20384787472035815 2.0634364015669812E-44 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 42 3 1525 10 1 false 0.20411339807916024 0.20411339807916024 1.2095302863090285E-289 negative_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043124 12133 32 42 1 297 2 3 false 0.20420420420417018 0.20420420420417018 1.1075051157890655E-43 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 42 7 307 8 1 false 0.2042182321840784 0.2042182321840784 1.4733469150792184E-83 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds GO:0016810 12133 82 42 1 2556 7 1 false 0.20429250056972828 0.20429250056972828 6.720612726716271E-157 ncRNA_metabolic_process GO:0034660 12133 258 42 4 3294 30 1 false 0.20441293868442248 0.20441293868442248 0.0 bHLH_transcription_factor_binding GO:0043425 12133 23 42 1 715 7 1 false 0.20535384968797338 0.20535384968797338 8.29405091807051E-44 cellular_response_to_glucocorticoid_stimulus GO:0071385 12133 20 42 1 97 1 2 false 0.20618556701030769 0.20618556701030769 3.671962810036931E-21 sarcoplasm GO:0016528 12133 47 42 1 6938 34 1 false 0.20678638352632023 0.20678638352632023 8.759395869796841E-122 MCM_complex GO:0042555 12133 36 42 1 2976 19 2 false 0.20701162121324415 0.20701162121324415 4.093123828825495E-84 MCM_core_complex GO:0097373 12133 36 42 1 2976 19 1 false 0.20701162121324415 0.20701162121324415 4.093123828825495E-84 nucleobase-containing_compound_transport GO:0015931 12133 135 42 2 1584 10 2 false 0.20709808701730406 0.20709808701730406 1.0378441909200412E-199 protein_kinase_inhibitor_activity GO:0004860 12133 46 42 1 1016 5 4 false 0.20715771216070364 0.20715771216070364 7.458157078887417E-81 nuclear_replication_fork GO:0043596 12133 28 42 1 256 2 3 false 0.2071691176470344 0.2071691176470344 5.235583786811974E-38 artery_development GO:0060840 12133 46 42 1 420 2 1 false 0.20728491874075494 0.20728491874075494 1.5213000183086255E-62 protein_complex_binding GO:0032403 12133 306 42 3 6397 33 1 false 0.20804442596318484 0.20804442596318484 0.0 negative_regulation_of_leukocyte_proliferation GO:0070664 12133 42 42 1 559 3 3 false 0.20923712491443625 0.20923712491443625 2.7701370341708057E-64 origin_recognition_complex GO:0000808 12133 37 42 1 3160 20 2 false 0.21043593502476837 0.21043593502476837 5.523329685243896E-87 negative_regulation_of_BMP_signaling_pathway GO:0030514 12133 27 42 1 128 1 3 false 0.21093749999999725 0.21093749999999725 2.661630263374797E-28 protein_autophosphorylation GO:0046777 12133 173 42 2 1195 6 1 false 0.2110255418014463 0.2110255418014463 7.421869914925723E-214 CMG_complex GO:0071162 12133 28 42 1 251 2 4 false 0.21105976095616433 0.21105976095616433 9.388589672695531E-38 cellular_protein_catabolic_process GO:0044257 12133 409 42 5 3174 25 3 false 0.2122870597354859 0.2122870597354859 0.0 cytoplasm GO:0005737 12133 6938 42 34 9083 41 1 false 0.21409570040775275 0.21409570040775275 0.0 wound_healing GO:0042060 12133 543 42 3 905 3 1 false 0.2155220062918256 0.2155220062918256 1.120707554751266E-263 embryonic_appendage_morphogenesis GO:0035113 12133 90 42 1 417 1 2 false 0.21582733812948507 0.21582733812948507 7.345969028832012E-94 negative_regulation_of_lymphocyte_proliferation GO:0050672 12133 40 42 1 185 1 4 false 0.2162162162162233 0.2162162162162233 1.5928211614930067E-41 nuclear_pre-replicative_complex GO:0005656 12133 28 42 1 821 7 4 false 0.216361331928128 0.216361331928128 1.2155097168867057E-52 GINS_complex GO:0000811 12133 28 42 1 244 2 2 false 0.21675774134786 0.21675774134786 2.171851500338737E-37 negative_regulation_of_protein_import_into_nucleus GO:0042308 12133 46 42 1 212 1 4 false 0.2169811320754646 0.2169811320754646 1.0466208389531854E-47 telomere_maintenance_via_semi-conservative_replication GO:0032201 12133 23 42 1 106 1 2 false 0.2169811320754754 0.2169811320754754 8.898323406667189E-24 MRF_binding GO:0043426 12133 5 42 1 23 1 1 false 0.2173913043478261 0.2173913043478261 2.971856518767258E-5 negative_regulation_of_hydrolase_activity GO:0051346 12133 241 42 2 2738 10 3 false 0.21778019746781635 0.21778019746781635 0.0 cardiac_muscle_tissue_morphogenesis GO:0055008 12133 49 42 1 223 1 3 false 0.2197309417040441 0.2197309417040441 1.5641814038205722E-50 purine_ribonucleotide_biosynthetic_process GO:0009152 12133 265 42 1 1206 1 3 false 0.2197346600332827 0.2197346600332827 5.7559641067065754E-275 cellular_response_to_reactive_oxygen_species GO:0034614 12133 71 42 1 606 2 3 false 0.22076753129865984 0.22076753129865984 1.6919333100015078E-94 cardiac_septum_development GO:0003279 12133 52 42 1 3152 15 3 false 0.22126652317970097 0.22126652317970097 1.458377917590102E-114 ATP_binding GO:0005524 12133 1212 42 5 1638 5 3 false 0.22131440535229158 0.22131440535229158 0.0 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 42 1 162 1 5 false 0.22222222222221105 0.22222222222221105 7.1760328941400225E-37 spindle_checkpoint GO:0031577 12133 45 42 1 202 1 1 false 0.22277227722771892 0.22277227722771892 4.3818533729449334E-46 chromosomal_part GO:0044427 12133 512 42 5 5337 34 2 false 0.22289858396839257 0.22289858396839257 0.0 peptidase_activity GO:0008233 12133 614 42 3 2556 7 1 false 0.22333607136408964 0.22333607136408964 0.0 regulation_of_hemostasis GO:1900046 12133 56 42 1 1801 8 2 false 0.22368772463166464 0.22368772463166464 8.285754301677846E-108 regulation_of_protein_oligomerization GO:0032459 12133 22 42 1 447 5 2 false 0.22393050729694464 0.22393050729694464 9.37826543019211E-38 fertilization GO:0009566 12133 65 42 1 546 2 2 false 0.2241153342071744 0.2241153342071744 5.279047514007133E-86 p53_binding GO:0002039 12133 49 42 1 6397 33 1 false 0.2246084143848076 0.2246084143848076 2.351284918255247E-124 heat_shock_protein_binding GO:0031072 12133 49 42 1 6397 33 1 false 0.2246084143848076 0.2246084143848076 2.351284918255247E-124 tyrosine_phosphorylation_of_STAT_protein GO:0007260 12133 51 42 1 227 1 2 false 0.22466960352423768 0.22466960352423768 4.751307982054789E-52 mesoderm_development GO:0007498 12133 92 42 1 1132 3 1 false 0.22471967055992717 0.22471967055992717 6.19400145712131E-138 B_cell_proliferation GO:0042100 12133 56 42 1 249 1 2 false 0.22489959839358484 0.22489959839358484 3.7670734683867574E-57 hydrolase_activity,_hydrolyzing_N-glycosyl_compounds GO:0016799 12133 16 42 1 71 1 1 false 0.2253521126760582 0.2253521126760582 3.1234669899124287E-16 regulation_of_blood_coagulation GO:0030193 12133 56 42 1 687 3 5 false 0.2254505856784637 0.2254505856784637 9.61940110686056E-84 ovulation_cycle GO:0042698 12133 77 42 1 640 2 3 false 0.22631553208143487 0.22631553208143487 1.431548427183746E-101 methylation GO:0032259 12133 195 42 2 8027 37 1 false 0.2265072234606371 0.2265072234606371 0.0 protein_K48-linked_ubiquitination GO:0070936 12133 37 42 1 163 1 1 false 0.22699386503067412 0.22699386503067412 1.6289154422281443E-37 mRNA_binding GO:0003729 12133 91 42 3 763 14 1 false 0.2275425478554972 0.2275425478554972 1.7788235024198917E-120 regulation_of_nuclear-transcribed_mRNA_poly(A)_tail_shortening GO:0060211 12133 8 42 1 35 1 3 false 0.22857142857142917 0.22857142857142917 4.248842827655879E-8 RNA_polymerase_II_transcription_regulatory_region_sequence-specific_DNA_binding_transcription_factor_activity_involved_in_negative_regulation_of_transcription GO:0001227 12133 30 42 1 594 5 2 false 0.2289680671001897 0.2289680671001897 3.4159415441689634E-51 DNA_strand_elongation GO:0022616 12133 40 42 1 791 5 1 false 0.22905447848639196 0.22905447848639196 2.6311932809577697E-68 somitogenesis GO:0001756 12133 48 42 1 2778 15 6 false 0.23057471913761973 0.23057471913761973 9.378192845488376E-105 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 42 11 7638 37 4 false 0.23087493116124272 0.23087493116124272 0.0 positive_regulation_of_response_to_DNA_damage_stimulus GO:2001022 12133 44 42 1 3212 19 4 false 0.23111618490378955 0.23111618490378955 1.7987290458431554E-100 negative_regulation_of_peptidyl-tyrosine_phosphorylation GO:0050732 12133 30 42 1 357 3 3 false 0.2321044575450385 0.2321044575450385 2.443461883518979E-44 cellular_response_to_corticosteroid_stimulus GO:0071384 12133 21 42 1 170 2 2 false 0.23243995823177863 0.23243995823177863 2.681415210742689E-27 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 42 8 2528 14 3 false 0.2334776497245646 0.2334776497245646 0.0 adenyl_ribonucleotide_binding GO:0032559 12133 1231 42 5 1645 5 2 false 0.2341914114340667 0.2341914114340667 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 42 5 1650 5 1 false 0.23443838307454945 0.23443838307454945 0.0 peptidyl-threonine_phosphorylation GO:0018107 12133 52 42 1 1196 6 2 false 0.23454316331823571 0.23454316331823571 2.255232718606443E-92 regulation_of_reactive_oxygen_species_metabolic_process GO:2000377 12133 53 42 1 3998 20 2 false 0.23474502660253194 0.23474502660253194 7.649010394596439E-122 phosphatidic_acid_biosynthetic_process GO:0006654 12133 16 42 1 128 2 2 false 0.23523622047243936 0.23523622047243936 1.071317370201523E-20 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 42 4 673 5 2 false 0.2353973193320656 0.2353973193320656 4.9348138289436974E-201 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 42 23 4989 32 5 false 0.235438102998704 0.235438102998704 0.0 negative_regulation_of_protein_kinase_activity GO:0006469 12133 163 42 2 1050 6 4 false 0.23562618929831006 0.23562618929831006 4.119509868513009E-196 regulation_of_cell_cycle GO:0051726 12133 659 42 4 6583 25 2 false 0.23674522602059173 0.23674522602059173 0.0 response_to_reactive_oxygen_species GO:0000302 12133 119 42 1 942 2 2 false 0.23681271448598604 0.23681271448598604 1.644560738396901E-154 protein_serine/threonine_phosphatase_activity GO:0004722 12133 49 42 1 206 1 1 false 0.23786407766990927 0.23786407766990927 1.2741001335034851E-48 G2_DNA_damage_checkpoint GO:0031572 12133 30 42 1 126 1 1 false 0.23809523809524394 0.23809523809524394 1.1088794169088006E-29 response_to_inorganic_substance GO:0010035 12133 277 42 2 2369 8 1 false 0.23835053746533613 0.23835053746533613 0.0 negative_regulation_of_transferase_activity GO:0051348 12133 180 42 2 2118 11 3 false 0.23879363784680288 0.23879363784680288 1.0892582554699503E-266 regulation_of_steroid_hormone_biosynthetic_process GO:0090030 12133 11 42 1 46 1 2 false 0.23913043478260615 0.23913043478260615 7.495811792367915E-11 somite_development GO:0061053 12133 56 42 1 3099 15 2 false 0.23978927399545502 0.23978927399545502 3.6356024552828968E-121 muscle_tissue_morphogenesis GO:0060415 12133 54 42 1 420 2 2 false 0.2408796454142382 0.2408796454142382 1.79772783426967E-69 proteasome_complex GO:0000502 12133 62 42 1 9248 41 2 false 0.24148748502391984 0.24148748502391984 4.919625587422917E-161 regulation_of_coagulation GO:0050818 12133 61 42 1 1798 8 2 false 0.24169684353600038 0.24169684353600038 4.077561831420737E-115 regulation_of_cell_morphogenesis_involved_in_differentiation GO:0010769 12133 167 42 2 879 5 3 false 0.24207721921196923 0.24207721921196923 7.212819447877608E-185 response_to_endogenous_stimulus GO:0009719 12133 982 42 5 5200 18 1 false 0.24231324030359735 0.24231324030359735 0.0 positive_regulation_of_mRNA_3'-end_processing GO:0031442 12133 12 42 1 93 2 3 false 0.24263674614305222 0.24263674614305222 2.4005002040937513E-15 prostate_gland_development GO:0030850 12133 45 42 1 508 3 3 false 0.24333838415558184 0.24333838415558184 1.535189924421617E-65 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 42 20 8688 38 3 false 0.24418344742517156 0.24418344742517156 0.0 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 42 4 5027 27 3 false 0.2443582857285502 0.2443582857285502 0.0 regulation_of_peptidase_activity GO:0052547 12133 276 42 2 1151 4 2 false 0.24441106590170897 0.24441106590170897 1.6233323078676786E-274 cytokine_biosynthetic_process GO:0042089 12133 89 42 1 364 1 2 false 0.24450549450550926 0.24450549450550926 2.424583571152321E-87 beta-catenin_binding GO:0008013 12133 54 42 1 6397 33 1 false 0.24456049679690123 0.24456049679690123 8.669980621574108E-135 regulation_of_mRNA_3'-end_processing GO:0031440 12133 15 42 1 115 2 2 false 0.2448512585812428 0.2448512585812428 4.172184298573769E-19 negative_regulation_of_metabolic_process GO:0009892 12133 1354 42 8 8327 37 3 false 0.24493941168582922 0.24493941168582922 0.0 monosaccharide_biosynthetic_process GO:0046364 12133 62 42 1 253 1 2 false 0.24505928853752568 0.24505928853752568 1.1247044052233336E-60 negative_regulation_of_mononuclear_cell_proliferation GO:0032945 12133 40 42 1 163 1 3 false 0.24539877300613244 0.24539877300613244 4.944296334627567E-39 single-stranded_DNA_binding GO:0003697 12133 58 42 2 179 3 1 false 0.24562387159031207 0.24562387159031207 1.7047154028422047E-48 single-organism_process GO:0044699 12133 8052 42 34 10446 41 1 false 0.24570567587583278 0.24570567587583278 0.0 regulation_of_catalytic_activity GO:0050790 12133 1692 42 8 6953 25 3 false 0.2472582309987147 0.2472582309987147 0.0 monocarboxylic_acid_binding GO:0033293 12133 46 42 1 186 1 1 false 0.24731182795700146 0.24731182795700146 9.660613526662205E-45 cell_motility GO:0048870 12133 785 42 3 1249 3 3 false 0.24791568496314978 0.24791568496314978 0.0 regulation_of_B_cell_activation GO:0050864 12133 78 42 1 314 1 2 false 0.24840764331208454 0.24840764331208454 6.891800701996175E-76 regulation_of_DNA_metabolic_process GO:0051052 12133 188 42 2 4316 22 3 false 0.24841181874720308 0.24841181874720308 0.0 RNA_methylation GO:0001510 12133 25 42 1 188 2 2 false 0.24889065877798863 0.24889065877798863 1.1533363650630908E-31 regulation_of_intracellular_transport GO:0032386 12133 276 42 3 1731 11 3 false 0.24997871452111223 0.24997871452111223 0.0 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 42 3 630 5 2 false 0.2506922649273034 0.2506922649273034 4.4826406352842784E-178 cyclic_nucleotide_metabolic_process GO:0009187 12133 177 42 1 1317 2 1 false 0.25081873005105243 0.25081873005105243 5.758082552903037E-225 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 42 1 2474 11 3 false 0.2509105385739272 0.2509105385739272 1.917782059478808E-128 phospholipid_biosynthetic_process GO:0008654 12133 143 42 2 4143 28 4 false 0.25155537910759634 0.25155537910759634 2.4357566319257345E-269 developmental_process GO:0032502 12133 3447 42 16 10446 41 1 false 0.2527274454693509 0.2527274454693509 0.0 regulation_of_neuron_differentiation GO:0045664 12133 281 42 2 853 3 2 false 0.2537985083290859 0.2537985083290859 5.679328733626827E-234 regulation_of_purine_nucleotide_biosynthetic_process GO:1900371 12133 146 42 1 574 1 3 false 0.25435540069685475 0.25435540069685475 1.1371703790830463E-140 pre-replicative_complex GO:0036387 12133 28 42 1 110 1 1 false 0.2545454545454507 0.2545454545454507 9.125355053770069E-27 heparin_binding GO:0008201 12133 95 42 1 2306 7 3 false 0.2553780797325806 0.2553780797325806 2.483692414324732E-171 Notch_signaling_pathway GO:0007219 12133 113 42 1 1975 5 1 false 0.2553893818101397 0.2553893818101397 2.33429872590278E-187 macromolecule_methylation GO:0043414 12133 149 42 2 5645 37 3 false 0.25543894937413014 0.25543894937413014 2.745935058350772E-298 regulation_of_metabolic_process GO:0019222 12133 4469 42 21 9189 38 2 false 0.25570723928815575 0.25570723928815575 0.0 muscle_system_process GO:0003012 12133 252 42 2 1272 5 1 false 0.2586930258372821 0.2586930258372821 3.711105192357829E-274 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 42 8 7606 37 4 false 0.2587373858418987 0.2587373858418987 0.0 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 42 9 5303 30 3 false 0.25895278423201973 0.25895278423201973 0.0 cellular_response_to_ionizing_radiation GO:0071479 12133 33 42 1 127 1 2 false 0.2598425196850416 0.2598425196850416 3.1340893590211945E-31 1-phosphatidylinositol-3-kinase_activity GO:0016303 12133 13 42 1 50 1 3 false 0.25999999999999795 0.25999999999999795 2.8180086191194757E-12 lipid_phosphorylation GO:0046834 12133 73 42 1 1493 6 2 false 0.2601454611407624 0.2601454611407624 5.261232871498249E-126 ovulation_cycle_process GO:0022602 12133 71 42 1 8057 34 3 false 0.26033947937522994 0.26033947937522994 5.317350826514013E-176 anchoring_junction GO:0070161 12133 197 42 2 588 3 1 false 0.2611531998767327 0.2611531998767327 4.1212451424432254E-162 steroid_hormone_mediated_signaling_pathway GO:0043401 12133 56 42 2 109 2 2 false 0.2616377845735662 0.2616377845735662 2.1050772619145757E-32 regulation_of_ventricular_cardiac_muscle_cell_membrane_depolarization GO:0060373 12133 5 42 1 19 1 2 false 0.2631578947368417 0.2631578947368417 8.599931200550397E-5 intracellular_organelle_lumen GO:0070013 12133 2919 42 21 5320 34 2 false 0.2632194505792481 0.2632194505792481 0.0 regulation_of_carbohydrate_biosynthetic_process GO:0043255 12133 52 42 1 3097 18 3 false 0.26334887720575567 0.26334887720575567 3.6702105296750396E-114 histone_deacetylase_complex GO:0000118 12133 50 42 1 3138 19 2 false 0.2636607082426544 0.2636607082426544 6.6201010514053174E-111 SMAD_binding GO:0046332 12133 59 42 1 6397 33 1 false 0.2640143480260239 0.2640143480260239 5.080833839367684E-145 cell_aging GO:0007569 12133 68 42 1 7548 34 2 false 0.2653580919274741 0.2653580919274741 6.81322307999876E-168 anatomical_structure_homeostasis GO:0060249 12133 166 42 2 990 6 1 false 0.2654628350389817 0.2654628350389817 1.128853988781411E-193 histone_modification GO:0016570 12133 306 42 3 2375 14 2 false 0.26589070537064285 0.26589070537064285 0.0 base-excision_repair GO:0006284 12133 36 42 1 368 3 1 false 0.266356542325616 0.266356542325616 9.30333826560927E-51 organelle_lumen GO:0043233 12133 2968 42 21 5401 34 2 false 0.2664864192910483 0.2664864192910483 0.0 dendrite GO:0030425 12133 276 42 2 534 2 1 false 0.26666947741225655 0.26666947741225655 6.975042602902724E-160 ERBB_signaling_pathway GO:0038127 12133 199 42 2 586 3 1 false 0.26727091927195856 0.26727091927195856 2.435227003721618E-162 cell_cycle_arrest GO:0007050 12133 202 42 2 998 5 2 false 0.2674552341164177 0.2674552341164177 1.5077994882682823E-217 tRNA_aminoacylation_for_protein_translation GO:0006418 12133 42 42 2 457 11 2 false 0.26778514982659557 0.26778514982659557 1.8852854762051817E-60 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 42 9 3972 26 4 false 0.26793883366341814 0.26793883366341814 0.0 envelope GO:0031975 12133 641 42 4 9983 41 1 false 0.26810165875809355 0.26810165875809355 0.0 DNA_replication GO:0006260 12133 257 42 3 3702 26 3 false 0.2684081008258631 0.2684081008258631 0.0 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 42 5 2780 8 2 false 0.26979802497761823 0.26979802497761823 0.0 molecular_transducer_activity GO:0060089 12133 1070 42 6 10257 42 1 false 0.27060924912703643 0.27060924912703643 0.0 mitotic_spindle_checkpoint GO:0071174 12133 38 42 1 140 1 2 false 0.27142857142856236 0.27142857142856236 3.73538767395573E-35 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 42 1 591 4 3 false 0.27212674677647325 0.27212674677647325 1.267222544612779E-68 regulation_of_tyrosine_phosphorylation_of_STAT_protein GO:0042509 12133 46 42 1 169 1 3 false 0.2721893491124171 0.2721893491124171 1.5655998786815088E-42 DNA_biosynthetic_process GO:0071897 12133 268 42 3 3979 27 3 false 0.27226715863915896 0.27226715863915896 0.0 segmentation GO:0035282 12133 67 42 1 246 1 1 false 0.2723577235772421 0.2723577235772421 4.801196781597085E-62 negative_regulation_of_cell_migration GO:0030336 12133 108 42 1 735 2 3 false 0.27245732080299107 0.27245732080299107 1.4353405807943923E-132 mismatch_base_pair_DNA_N-glycosylase_activity GO:0000700 12133 3 42 1 11 1 1 false 0.27272727272727315 0.27272727272727315 0.006060606060606057 glycerolipid_biosynthetic_process GO:0045017 12133 152 42 2 4148 28 3 false 0.27394240609609916 0.27394240609609916 2.64642542744153E-282 CHD-type_complex GO:0090545 12133 16 42 1 58 1 1 false 0.27586206896552057 0.27586206896552057 1.250622453533436E-14 urogenital_system_development GO:0001655 12133 231 42 2 2686 12 1 false 0.27627243463760065 0.27627243463760065 0.0 hexose_biosynthetic_process GO:0019319 12133 57 42 1 206 1 2 false 0.2766990291262256 0.2766990291262256 2.7565278967151444E-52 reciprocal_meiotic_recombination GO:0007131 12133 33 42 1 1243 12 4 false 0.27700043757431647 0.27700043757431647 1.0168261018961741E-65 negative_regulation_of_leukocyte_activation GO:0002695 12133 79 42 1 528 2 4 false 0.27709734920359097 0.27709734920359097 3.4167726951428884E-96 DNA_repair GO:0006281 12133 368 42 3 977 5 2 false 0.27753420982804294 0.27753420982804294 3.284245924949814E-280 'de_novo'_protein_folding GO:0006458 12133 51 42 1 183 1 1 false 0.27868852459015203 0.27868852459015203 1.4322240237766098E-46 coagulation GO:0050817 12133 446 42 3 4095 17 1 false 0.2803645587473617 0.2803645587473617 0.0 alpha-beta_T_cell_activation GO:0046631 12133 81 42 1 288 1 1 false 0.28124999999998007 0.28124999999998007 9.337463390068025E-74 positive_regulation_of_peptidyl-serine_phosphorylation GO:0033138 12133 47 42 1 594 4 3 false 0.28150285782908385 0.28150285782908385 7.186758669481106E-71 organophosphate_biosynthetic_process GO:0090407 12133 477 42 4 4948 28 2 false 0.281829322054829 0.281829322054829 0.0 positive_regulation_of_purine_nucleotide_biosynthetic_process GO:1900373 12133 77 42 1 273 1 4 false 0.2820512820512513 0.2820512820512513 5.5014514459438226E-70 signal_transducer_activity GO:0004871 12133 1070 42 6 3547 15 2 false 0.28296661911718846 0.28296661911718846 0.0 RNA_polymerase_II_repressing_transcription_factor_binding GO:0001103 12133 31 42 1 296 3 2 false 0.2832883038693895 0.2832883038693895 1.0279031855917918E-42 cytoplasmic_sequestering_of_protein GO:0051220 12133 24 42 1 156 2 2 false 0.28486352357317773 0.28486352357317773 9.286705188012584E-29 mRNA_splice_site_selection GO:0006376 12133 18 42 1 117 2 2 false 0.2851458885941616 0.2851458885941616 1.505085052005422E-21 mammary_gland_morphogenesis GO:0060443 12133 50 42 1 175 1 2 false 0.2857142857142999 0.2857142857142999 5.092262443140402E-45 regulation_of_cAMP_metabolic_process GO:0030814 12133 133 42 1 465 1 3 false 0.28602150537631577 0.28602150537631577 3.255746313776628E-120 kinase_binding GO:0019900 12133 384 42 3 1005 5 1 false 0.28658380374991343 0.28658380374991343 2.0091697589355545E-289 receptor_signaling_protein_activity GO:0005057 12133 339 42 3 1070 6 1 false 0.28706390893590367 0.28706390893590367 2.5248591221043436E-289 negative_regulation_of_cellular_catabolic_process GO:0031330 12133 54 42 1 2906 18 4 false 0.28725250001688085 0.28725250001688085 3.6352902453771176E-116 maintenance_of_protein_location_in_cell GO:0032507 12133 90 42 2 933 11 3 false 0.2874885365813341 0.2874885365813341 6.448935914517526E-128 regulation_of_steroid_biosynthetic_process GO:0050810 12133 42 42 1 146 1 3 false 0.2876712328767199 0.2876712328767199 1.231507741439357E-37 regulation_of_nuclease_activity GO:0032069 12133 68 42 1 4238 21 4 false 0.28858161634938917 0.28858161634938917 9.59850159009872E-151 regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014066 12133 54 42 1 1607 10 2 false 0.29020780413973274 0.29020780413973274 4.2614304493416375E-102 regulation_of_dendrite_development GO:0050773 12133 64 42 1 220 1 2 false 0.2909090909090897 0.2909090909090897 4.1507803256467186E-57 regulation_of_catabolic_process GO:0009894 12133 554 42 4 5455 27 2 false 0.29162165967971476 0.29162165967971476 0.0 gluconeogenesis GO:0006094 12133 54 42 1 185 1 2 false 0.2918918918919016 0.2918918918919016 4.74373526943691E-48 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 42 1 195 1 4 false 0.2923076923077087 0.2923076923077087 1.081664723883568E-50 divalent_inorganic_cation_transmembrane_transporter_activity GO:0072509 12133 126 42 1 431 1 2 false 0.29234338747102684 0.29234338747102684 1.8747555941678357E-112 SWI/SNF_superfamily-type_complex GO:0070603 12133 58 42 1 4399 26 2 false 0.2925413730820072 0.2925413730820072 1.6616943728575192E-133 protein_deacylation GO:0035601 12133 58 42 1 2370 14 1 false 0.29379168244530374 0.29379168244530374 8.732809717864973E-118 ventricular_cardiac_muscle_tissue_development GO:0003229 12133 38 42 1 129 1 1 false 0.29457364341085457 0.29457364341085457 1.4215032216275827E-33 nuclear_envelope_reassembly GO:0031468 12133 8 42 1 27 1 1 false 0.2962962962962964 0.2962962962962964 4.504352330439255E-7 peptidyl-amino_acid_modification GO:0018193 12133 623 42 5 2370 14 1 false 0.29677341265925544 0.29677341265925544 0.0 positive_regulation_of_epithelial_cell_proliferation GO:0050679 12133 105 42 1 649 2 3 false 0.2976088569309488 0.2976088569309488 4.1265464719999905E-124 RNA_polymerase_II_transcription_factor_binding_transcription_factor_activity_involved_in_positive_regulation_of_transcription GO:0001190 12133 30 42 1 697 8 2 false 0.2979727975298194 0.2979727975298194 2.5213218262735515E-53 regulation_of_BMP_signaling_pathway GO:0030510 12133 48 42 1 161 1 2 false 0.2981366459627381 0.2981366459627381 3.648915121282221E-42 regulation_of_endopeptidase_activity GO:0052548 12133 264 42 2 480 2 2 false 0.3019832985387032 0.3019832985387032 9.691263405564588E-143 DNA_methylation GO:0006306 12133 37 42 1 225 2 4 false 0.30246031746029456 0.30246031746029456 2.946192449924989E-43 carboxylic_ester_hydrolase_activity GO:0052689 12133 92 42 1 814 3 1 false 0.302516434467041 0.302516434467041 4.359236908507715E-124 mRNA_cis_splicing,_via_spliceosome GO:0045292 12133 10 42 1 202 7 1 false 0.3029813246677161 0.3029813246677161 4.0230126285336683E-17 negative_regulation_of_cell_differentiation GO:0045596 12133 381 42 3 3552 18 4 false 0.30306263116711296 0.30306263116711296 0.0 intrinsic_apoptotic_signaling_pathway_in_response_to_DNA_damage GO:0008630 12133 45 42 1 647 5 2 false 0.30344267048983053 0.30344267048983053 1.851108938674389E-70 DNA_modification GO:0006304 12133 62 42 1 2948 17 2 false 0.3039533304060471 0.3039533304060471 4.6529599905384535E-130 acylglycerol_O-acyltransferase_activity GO:0016411 12133 7 42 1 23 1 1 false 0.30434782608695654 0.30434782608695654 4.079018751249198E-6 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 42 6 1399 12 3 false 0.30502562813692535 0.30502562813692535 0.0 positive_regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900740 12133 24 42 2 43 2 3 false 0.30564784053156213 0.30564784053156213 1.2492622608986976E-12 protein_kinase_C_binding GO:0005080 12133 39 42 1 341 3 1 false 0.306156220565716 0.306156220565716 3.262596721977534E-52 signal_transduction GO:0007165 12133 3547 42 15 6702 25 4 false 0.30675538174144623 0.30675538174144623 0.0 biological_adhesion GO:0022610 12133 714 42 4 10446 41 1 false 0.3067944534667302 0.3067944534667302 0.0 cellular_response_to_lipid GO:0071396 12133 242 42 2 1527 7 2 false 0.30714127488927545 0.30714127488927545 4.5218037632292525E-289 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 42 1 695 3 3 false 0.30748935789060194 0.30748935789060194 3.5521820546065696E-107 organic_substance_transport GO:0071702 12133 1580 42 10 2783 15 1 false 0.307523374278508 0.307523374278508 0.0 regulation_of_protein_localization GO:0032880 12133 349 42 3 2148 12 2 false 0.30755131809572245 0.30755131809572245 0.0 transcriptional_repressor_complex GO:0017053 12133 60 42 1 3138 19 2 false 0.30779508085191476 0.30779508085191476 2.3309177667820233E-128 negative_regulation_of_apoptotic_process GO:0043066 12133 537 42 6 1377 12 3 false 0.30792874845180024 0.30792874845180024 0.0 recombinational_repair GO:0000725 12133 48 42 1 416 3 2 false 0.3084028421378511 0.3084028421378511 4.005015877906007E-64 small_conjugating_protein_binding GO:0032182 12133 71 42 1 6397 33 1 false 0.3087423964367288 0.3087423964367288 7.493300865579233E-169 perinuclear_region_of_cytoplasm GO:0048471 12133 416 42 3 5117 24 1 false 0.309276641439136 0.309276641439136 0.0 regulation_of_B_cell_proliferation GO:0030888 12133 48 42 1 155 1 3 false 0.3096774193548386 0.3096774193548386 3.1792574555174185E-41 immune_system_development GO:0002520 12133 521 42 3 3460 13 2 false 0.31012691900813516 0.31012691900813516 0.0 membrane_depolarization GO:0051899 12133 67 42 1 216 1 1 false 0.31018518518518196 0.31018518518518196 1.3863236274118357E-57 activating_transcription_factor_binding GO:0033613 12133 294 42 4 715 7 1 false 0.3109939630873293 0.3109939630873293 1.6086726333731214E-209 nucleus_organization GO:0006997 12133 62 42 1 2031 12 1 false 0.3113740072067974 0.3113740072067974 6.73570952581451E-120 transferase_activity GO:0016740 12133 1779 42 8 4901 18 1 false 0.3119416293935337 0.3119416293935337 0.0 regulation_of_mRNA_processing GO:0050684 12133 49 42 1 3175 24 3 false 0.31247083982664364 0.31247083982664364 2.292701139367024E-109 steroid_binding GO:0005496 12133 59 42 1 4749 30 2 false 0.31353616791154176 0.31353616791154176 2.396693248406128E-137 regulation_of_wound_healing GO:0061041 12133 78 42 1 1077 5 2 false 0.31382772735186615 0.31382772735186615 6.057145898993517E-121 cell-cell_adherens_junction GO:0005913 12133 40 42 1 340 3 2 false 0.31385896768504107 0.31385896768504107 4.895581977048006E-53 response_to_laminar_fluid_shear_stress GO:0034616 12133 12 42 2 21 2 1 false 0.3142857142857156 0.3142857142857156 3.4021705848331363E-6 poly(A)_RNA_binding GO:0008143 12133 11 42 1 94 3 2 false 0.31454596998000534 0.31454596998000534 1.4483869139240058E-14 adherens_junction_assembly GO:0034333 12133 52 42 1 165 1 2 false 0.3151515151515289 0.3151515151515289 3.3179738133462556E-44 neuron_apoptotic_process GO:0051402 12133 158 42 2 281 2 2 false 0.3152770716827504 0.3152770716827504 4.7762266380223384E-83 cell_proliferation GO:0008283 12133 1316 42 7 8052 34 1 false 0.31572207951566134 0.31572207951566134 0.0 negative_regulation_of_lymphocyte_activation GO:0051250 12133 71 42 1 411 2 3 false 0.3160049848674232 0.3160049848674232 1.371675996029936E-81 reciprocal_DNA_recombination GO:0035825 12133 33 42 1 190 2 1 false 0.31796157059313146 0.31796157059313146 1.0521505820531533E-37 lipid_metabolic_process GO:0006629 12133 769 42 5 7599 37 3 false 0.31826079662546264 0.31826079662546264 0.0 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 42 2 308 2 2 false 0.31835103007736393 0.31835103007736393 5.66231040699253E-91 cell-cell_junction GO:0005911 12133 222 42 2 588 3 1 false 0.31970366508264203 0.31970366508264203 1.5852162200644845E-168 regulation_of_endothelial_cell_proliferation GO:0001936 12133 63 42 1 197 1 2 false 0.31979695431470434 0.31979695431470434 3.9481293068221625E-53 transcription_factor_import_into_nucleus GO:0042991 12133 64 42 1 200 1 1 false 0.3199999999999909 0.3199999999999909 5.887023324562289E-54 maintenance_of_location GO:0051235 12133 184 42 2 4158 26 2 false 0.32075596970006753 0.32075596970006753 0.0 stem_cell_maintenance GO:0019827 12133 93 42 1 4373 18 4 false 0.3213807286207569 0.3213807286207569 7.918520551520462E-195 O-acyltransferase_activity GO:0008374 12133 23 42 1 131 2 1 false 0.321432765707564 0.321432765707564 4.0422990394657154E-26 mitochondrial_part GO:0044429 12133 557 42 4 7185 37 3 false 0.32183507912957976 0.32183507912957976 0.0 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 42 2 856 4 3 false 0.3218824993045136 0.3218824993045136 2.175375701359491E-221 cell_migration_involved_in_sprouting_angiogenesis GO:0002042 12133 22 42 1 68 1 2 false 0.323529411764705 0.323529411764705 2.4938962391792082E-18 gene_silencing GO:0016458 12133 87 42 1 7626 34 2 false 0.3235958463838462 0.3235958463838462 5.995921436880012E-206 regulation_of_protein_metabolic_process GO:0051246 12133 1388 42 9 5563 30 3 false 0.32377123453077516 0.32377123453077516 0.0 lamellipodium GO:0030027 12133 121 42 1 990 3 2 false 0.32396346314162955 0.32396346314162955 5.739208350847419E-159 regulation_of_kinase_activity GO:0043549 12133 654 42 4 1335 6 3 false 0.3246065206597064 0.3246065206597064 0.0 positive_regulation_of_nucleotide_metabolic_process GO:0045981 12133 83 42 1 2578 12 4 false 0.3253467015242574 0.3253467015242574 1.0942419479084622E-158 regulation_of_cyclic_nucleotide_metabolic_process GO:0030799 12133 156 42 1 478 1 2 false 0.3263598326359788 0.3263598326359788 1.998151187516486E-130 regulatory_region_DNA_binding GO:0000975 12133 1169 42 8 2091 12 2 false 0.3266959780917009 0.3266959780917009 0.0 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 42 1 254 1 3 false 0.3267716535432695 0.3267716535432695 3.7262148804586973E-69 response_to_lipid GO:0033993 12133 515 42 3 1783 7 1 false 0.32758864886561156 0.32758864886561156 0.0 signal_transduction_by_phosphorylation GO:0023014 12133 307 42 2 3947 15 2 false 0.3277021032792121 0.3277021032792121 0.0 microtubule_organizing_center_organization GO:0031023 12133 66 42 1 2031 12 2 false 0.32802096295639005 0.32802096295639005 7.775037316859227E-126 ion_transmembrane_transport GO:0034220 12133 556 42 2 970 2 2 false 0.32830104369452756 0.32830104369452756 1.3121997139332702E-286 glycerophospholipid_biosynthetic_process GO:0046474 12133 128 42 2 223 2 3 false 0.3283642386781312 0.3283642386781312 1.5941891805992847E-65 platelet_degranulation GO:0002576 12133 81 42 1 246 1 1 false 0.3292682926829352 0.3292682926829352 3.708744059509268E-67 negative_regulation_of_protein_modification_process GO:0031400 12133 328 42 3 2431 15 3 false 0.32969771093662237 0.32969771093662237 0.0 protein_localization_to_mitochondrion GO:0070585 12133 67 42 2 516 9 1 false 0.3300285972070836 0.3300285972070836 5.765661430685337E-86 regulation_of_RNA_splicing GO:0043484 12133 52 42 1 3151 24 3 false 0.3302470543580382 0.3302470543580382 1.4828410310444421E-114 response_to_steroid_hormone_stimulus GO:0048545 12133 272 42 2 938 4 3 false 0.33054681663294305 0.33054681663294305 1.788442659003846E-244 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 42 9 5462 33 2 false 0.3317625405697407 0.3317625405697407 0.0 positive_regulation_of_proteasomal_protein_catabolic_process GO:1901800 12133 36 42 1 287 3 4 false 0.3320863988386028 0.3320863988386028 1.2079535246838254E-46 ER-nucleus_signaling_pathway GO:0006984 12133 94 42 1 3547 15 1 false 0.33214851192238426 0.33214851192238426 7.751301219638514E-188 meiosis GO:0007126 12133 122 42 2 1243 12 2 false 0.33261984254063204 0.33261984254063204 1.368721434688107E-172 negative_regulation_of_NF-kappaB_import_into_nucleus GO:0042347 12133 17 42 1 51 1 3 false 0.3333333333333329 0.3333333333333329 6.76999067656327E-14 regulation_of_RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0045898 12133 5 42 1 15 1 2 false 0.33333333333333326 0.33333333333333326 3.330003330003327E-4 purine-specific_mismatch_base_pair_DNA_N-glycosylase_activity GO:0000701 12133 1 42 1 3 1 1 false 0.33333333333333337 0.33333333333333337 0.33333333333333337 endothelial_cell_proliferation GO:0001935 12133 75 42 1 225 1 1 false 0.3333333333333436 0.3333333333333436 1.1255244798812847E-61 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 42 4 3605 25 4 false 0.3347914918322926 0.3347914918322926 0.0 mitotic_recombination GO:0006312 12133 35 42 1 190 2 1 false 0.33528265107210586 0.33528265107210586 5.112114946281329E-39 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 42 9 5528 33 2 false 0.33541480615749086 0.33541480615749086 0.0 platelet_activation GO:0030168 12133 203 42 2 863 5 2 false 0.3359752987224495 0.3359752987224495 1.0918730712206789E-203 regulation_of_cell_cycle_arrest GO:0071156 12133 89 42 1 481 2 2 false 0.33613998614007884 0.33613998614007884 1.91357850692127E-99 regulation_of_proteasomal_protein_catabolic_process GO:0061136 12133 67 42 1 1672 10 5 false 0.3364130934919355 0.3364130934919355 1.5388096674355026E-121 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 42 3 912 5 2 false 0.33659631199769724 0.33659631199769724 2.059888800891414E-267 regulation_of_transferase_activity GO:0051338 12133 667 42 4 2708 12 2 false 0.33964767667674867 0.33964767667674867 0.0 activation_of_MAPKK_activity GO:0000186 12133 64 42 1 496 3 3 false 0.3398910088215636 0.3398910088215636 2.7437381948522894E-82 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 42 1 953 5 3 false 0.3406177604949722 0.3406177604949722 1.5807807987211998E-114 cellular_response_to_radiation GO:0071478 12133 68 42 1 361 2 2 false 0.34167436134190804 0.34167436134190804 2.589995599441981E-75 integral_to_plasma_membrane GO:0005887 12133 801 42 1 2339 1 2 false 0.3424540401883036 0.3424540401883036 0.0 cell_activation GO:0001775 12133 656 42 4 7541 34 1 false 0.34262473958863193 0.34262473958863193 0.0 cellular_response_to_oxygen_levels GO:0071453 12133 85 42 1 1663 8 2 false 0.34336670729653707 0.34336670729653707 4.192529980934564E-145 regulation_of_cytokine_biosynthetic_process GO:0042035 12133 80 42 1 3656 19 5 false 0.34388623018311193 0.34388623018311193 1.557250442043908E-166 termination_of_RNA_polymerase_II_transcription GO:0006369 12133 44 42 1 1385 13 2 false 0.34397619125240464 0.34397619125240464 3.166663017097352E-84 heterocycle_catabolic_process GO:0046700 12133 1243 42 9 5392 33 2 false 0.3440976478042961 0.3440976478042961 0.0 myeloid_cell_homeostasis GO:0002262 12133 111 42 1 1628 6 2 false 0.3458255100264217 0.3458255100264217 2.626378318706563E-175 protein_heterooligomerization GO:0051291 12133 55 42 1 288 2 1 false 0.3460123886952563 0.3460123886952563 1.7091560629948947E-60 regulation_of_JAK-STAT_cascade GO:0046425 12133 66 42 1 656 4 2 false 0.34634789397570803 0.34634789397570803 1.950107224419378E-92 ureteric_bud_development GO:0001657 12133 84 42 1 439 2 2 false 0.3464286828720442 0.3464286828720442 1.7545381819283125E-92 DNA_recombination GO:0006310 12133 190 42 2 791 5 1 false 0.346474535249834 0.346474535249834 1.2250789605162758E-188 RNA_stabilization GO:0043489 12133 22 42 2 37 2 1 false 0.3468468468468479 0.3468468468468479 1.0678969112465738E-10 regulation_of_embryonic_development GO:0045995 12133 73 42 1 1410 8 2 false 0.34713144796136636 0.34713144796136636 3.810799800640736E-124 circulatory_system_process GO:0003013 12133 307 42 2 1272 5 1 false 0.34892198767379046 0.34892198767379046 1.974873217376429E-304 protein_complex_biogenesis GO:0070271 12133 746 42 6 1525 10 1 false 0.3501581797769502 0.3501581797769502 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 42 9 5388 33 2 false 0.3507326231035268 0.3507326231035268 0.0 sequence-specific_DNA_binding GO:0043565 12133 1189 42 8 2091 12 1 false 0.3515773536293131 0.3515773536293131 0.0 positive_regulation_of_endothelial_cell_proliferation GO:0001938 12133 47 42 1 133 1 3 false 0.3533834586466319 0.3533834586466319 4.212877934639662E-37 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 42 3 381 4 2 false 0.3540643726992025 0.3540643726992025 8.855041133991382E-114 regulation_of_ion_homeostasis GO:2000021 12133 124 42 1 630 2 2 false 0.35516188457374487 0.35516188457374487 4.993626171436977E-135 regulation_of_cell_proliferation GO:0042127 12133 999 42 5 6358 25 2 false 0.35529003697858313 0.35529003697858313 0.0 regulation_of_biosynthetic_process GO:0009889 12133 3012 42 18 5483 30 2 false 0.3560225039300789 0.3560225039300789 0.0 hormone_metabolic_process GO:0042445 12133 95 42 1 8045 37 2 false 0.35629181402827476 0.35629181402827476 1.7025855797874937E-223 histone_acetyltransferase_complex GO:0000123 12133 72 42 1 3138 19 2 false 0.3574498438016573 0.3574498438016573 2.423530971941831E-148 protein_N-terminus_binding GO:0047485 12133 85 42 1 6397 33 1 false 0.35759822495972277 0.35759822495972277 1.5319897739448716E-195 cell_chemotaxis GO:0060326 12133 132 42 1 2155 7 3 false 0.35795785061857566 0.35795785061857566 6.49351277121459E-215 regulation_of_receptor_activity GO:0010469 12133 89 42 1 3057 15 3 false 0.3586750708877913 0.3586750708877913 3.874143452259453E-174 negative_regulation_of_cell_motility GO:2000146 12133 110 42 1 800 3 4 false 0.35876518580549177 0.35876518580549177 1.883997981968334E-138 removal_of_superoxide_radicals GO:0019430 12133 14 42 1 39 1 2 false 0.3589743589743575 0.3589743589743575 6.629319556996302E-11 peptidyl-threonine_modification GO:0018210 12133 53 42 1 623 5 1 false 0.3598487795444497 0.3598487795444497 3.249714987562728E-78 erythrocyte_differentiation GO:0030218 12133 88 42 1 243 1 2 false 0.3621399176954674 0.3621399176954674 1.540826297870933E-68 cell_cycle GO:0007049 12133 1295 42 7 7541 34 1 false 0.36464065542671864 0.36464065542671864 0.0 dendritic_spine GO:0043197 12133 121 42 1 596 2 3 false 0.36509503130110676 0.36509503130110676 6.183643418341279E-130 regulation_of_cellular_carbohydrate_metabolic_process GO:0010675 12133 91 42 1 4058 20 3 false 0.36534867862447634 0.36534867862447634 1.6448652824301034E-188 regulation_of_nuclear_division GO:0051783 12133 100 42 1 712 3 2 false 0.3653788754430467 0.3653788754430467 7.811073934054147E-125 RNA_polymerase_II_transcription_cofactor_activity GO:0001104 12133 67 42 1 477 3 3 false 0.365621601172811 0.365621601172811 1.6403588657259362E-83 regulation_of_translational_elongation GO:0006448 12133 15 42 1 308 9 2 false 0.3658334718147628 0.3658334718147628 8.683071731337218E-26 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 42 4 3910 25 3 false 0.36585805163501484 0.36585805163501484 0.0 regulation_of_carbohydrate_metabolic_process GO:0006109 12133 96 42 1 4268 20 2 false 0.3662010328386 0.3662010328386 9.169265262763212E-199 cardiac_chamber_morphogenesis GO:0003206 12133 84 42 1 2812 15 4 false 0.3662256502852363 0.3662256502852363 2.2227786094591774E-163 neural_precursor_cell_proliferation GO:0061351 12133 83 42 1 1316 7 1 false 0.3668855797694319 0.3668855797694319 7.00043909910839E-134 cyclase_activity GO:0009975 12133 123 42 1 4901 18 1 false 0.36765205918243926 0.36765205918243926 7.077862449152851E-249 calcium_ion_transmembrane_transport GO:0070588 12133 131 42 1 640 2 2 false 0.36773278560260514 0.36773278560260514 3.4276218198079466E-140 mitochondrion_organization GO:0007005 12133 215 42 2 2031 12 1 false 0.36804541851119577 0.36804541851119577 4.082912305313268E-297 nuclear_import GO:0051170 12133 203 42 2 2389 15 3 false 0.3686197065249216 0.3686197065249216 7.452348105569065E-301 microtubule_cytoskeleton GO:0015630 12133 734 42 4 1430 6 1 false 0.368689430362632 0.368689430362632 0.0 cellular_lipid_metabolic_process GO:0044255 12133 606 42 4 7304 37 2 false 0.3689543887507001 0.3689543887507001 0.0 RNA_modification GO:0009451 12133 64 42 1 4775 34 2 false 0.3689637473559395 0.3689637473559395 6.812362595459872E-147 MAP_kinase_kinase_activity GO:0004708 12133 74 42 1 521 3 3 false 0.36905141888598725 0.36905141888598725 6.903948166738437E-92 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 42 1 415 4 1 false 0.36926596345186424 0.36926596345186424 2.1919403735850567E-61 female_sex_differentiation GO:0046660 12133 93 42 1 3074 15 2 false 0.3699029991252794 0.3699029991252794 2.0765356282751238E-180 regulation_of_glucose_metabolic_process GO:0010906 12133 74 42 1 200 1 2 false 0.3699999999999865 0.3699999999999865 9.949659617427537E-57 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 42 1 2735 16 4 false 0.3713831175091167 0.3713831175091167 2.836340851870023E-153 exocytosis GO:0006887 12133 246 42 1 1184 2 2 false 0.3725111946265245 0.3725111946265245 6.194714731116342E-262 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 42 2 147 2 1 false 0.37321778026277286 0.37321778026277286 3.485982605742994E-42 response_to_organic_substance GO:0010033 12133 1783 42 7 2369 8 1 false 0.3732995408483496 0.3732995408483496 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 42 1 341 2 4 false 0.37355528721748876 0.37355528721748876 3.257446469032824E-75 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 42 1 1211 1 2 false 0.37489677952107425 0.37489677952107425 0.0 cardiac_chamber_development GO:0003205 12133 97 42 1 3152 15 3 false 0.3749506673703509 0.3749506673703509 1.855454637973827E-187 superoxide_metabolic_process GO:0006801 12133 39 42 1 104 1 1 false 0.3749999999999917 0.3749999999999917 1.6335016088161397E-29 regulation_of_glucocorticoid_biosynthetic_process GO:0031946 12133 6 42 1 16 1 3 false 0.375 0.375 1.248751248751251E-4 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 42 1 170 1 3 false 0.37647058823527946 0.37647058823527946 2.004129732487635E-48 positive_regulation_of_translation GO:0045727 12133 48 42 1 2063 20 5 false 0.37690032647169847 0.37690032647169847 1.726838216473461E-98 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 42 7 4597 17 2 false 0.3774402172171507 0.3774402172171507 0.0 response_to_gamma_radiation GO:0010332 12133 37 42 1 98 1 1 false 0.37755102040815625 0.37755102040815625 7.410936592166628E-28 histone_acetyltransferase_activity GO:0004402 12133 52 42 1 137 1 2 false 0.3795620437956287 0.3795620437956287 4.532765208696966E-39 purine_nucleotide_biosynthetic_process GO:0006164 12133 269 42 1 1265 2 3 false 0.3802096362636539 0.3802096362636539 1.9379490968147627E-283 positive_regulation_of_proteolysis GO:0045862 12133 69 42 1 1334 9 3 false 0.3808866307702632 0.3808866307702632 2.369917275782091E-117 regulation_of_cell-cell_adhesion GO:0022407 12133 65 42 1 440 3 2 false 0.3816698910974741 0.3816698910974741 1.791937567438994E-79 ventricular_septum_development GO:0003281 12133 34 42 1 89 1 2 false 0.3820224719101108 0.3820224719101108 2.2706596082310485E-25 gland_development GO:0048732 12133 251 42 2 2873 15 2 false 0.38202991884924065 0.38202991884924065 0.0 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 42 1 1014 5 1 false 0.382446562382399 0.382446562382399 2.468210871514413E-134 negative_regulation_of_catabolic_process GO:0009895 12133 83 42 1 3124 18 3 false 0.384944410541731 0.384944410541731 1.0289413364876372E-165 chromosome_organization GO:0051276 12133 689 42 5 2031 12 1 false 0.38526382463979814 0.38526382463979814 0.0 DNA_strand_elongation_involved_in_DNA_replication GO:0006271 12133 37 42 1 96 1 2 false 0.38541666666666446 0.38541666666666446 1.924818667899983E-27 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 42 9 3847 31 4 false 0.3882544527472561 0.3882544527472561 0.0 cellular_response_to_topologically_incorrect_protein GO:0035967 12133 87 42 1 2172 12 3 false 0.38849190453880655 0.38849190453880655 5.95891199322288E-158 endocrine_system_development GO:0035270 12133 108 42 1 2686 12 1 false 0.3895157106309701 0.3895157106309701 5.316219465834033E-196 chromosome,_telomeric_region GO:0000781 12133 48 42 1 512 5 1 false 0.3899616013664715 0.3899616013664715 1.088424225361165E-68 replication_fork GO:0005657 12133 48 42 1 512 5 1 false 0.3899616013664715 0.3899616013664715 1.088424225361165E-68 ribonucleotide_biosynthetic_process GO:0009260 12133 275 42 1 1250 2 3 false 0.3917373899121937 0.3917373899121937 3.3374763917028038E-285 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 42 2 587 3 2 false 0.3919741477230232 0.3919741477230232 2.854325455984618E-173 cellular_response_to_oxidative_stress GO:0034599 12133 95 42 1 2340 12 3 false 0.3925846419832684 0.3925846419832684 6.007102514115277E-172 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 42 2 1256 14 1 false 0.39279420467025683 0.39279420467025683 3.1457660386089413E-171 histone_deacetylation GO:0016575 12133 48 42 1 314 3 2 false 0.3931199546672597 0.3931199546672597 7.70276345269051E-58 cell_junction GO:0030054 12133 588 42 3 10701 41 1 false 0.3933998921394263 0.3933998921394263 0.0 histone_deacetylase_activity GO:0004407 12133 26 42 1 66 1 3 false 0.39393939393939675 0.39393939393939675 6.044910921634578E-19 transcription_coactivator_activity GO:0003713 12133 264 42 3 478 4 2 false 0.39415523749414827 0.39415523749414827 4.798051856605128E-142 taxis GO:0042330 12133 488 42 2 1496 4 2 false 0.39472028910172896 0.39472028910172896 0.0 lipoprotein_metabolic_process GO:0042157 12133 68 42 1 3431 25 1 false 0.3948233179817836 0.3948233179817836 1.8884569574824633E-144 hydrolase_activity,_acting_on_ester_bonds GO:0016788 12133 814 42 3 2556 7 1 false 0.3950881349329737 0.3950881349329737 0.0 JAK-STAT_cascade GO:0007259 12133 96 42 1 806 4 1 false 0.39847353541830316 0.39847353541830316 3.5358394194592134E-127 multicellular_organismal_signaling GO:0035637 12133 604 42 3 5594 21 2 false 0.3993150453710902 0.3993150453710902 0.0 positive_regulation_of_adenylate_cyclase_activity GO:0045762 12133 52 42 1 130 1 5 false 0.3999999999999939 0.3999999999999939 1.4124265749856537E-37 divalent_inorganic_cation_transport GO:0072511 12133 243 42 1 606 1 1 false 0.40099009900993665 0.40099009900993665 1.781632444658852E-176 cell_adhesion GO:0007155 12133 712 42 4 7542 34 2 false 0.40191305334822286 0.40191305334822286 0.0 neuron_spine GO:0044309 12133 121 42 1 534 2 1 false 0.4021684901379746 0.4021684901379746 1.9159133440155296E-123 alpha-beta_T_cell_differentiation GO:0046632 12133 62 42 1 154 1 2 false 0.4025974025973964 0.4025974025973964 1.2668794331681672E-44 negative_regulation_of_nucleocytoplasmic_transport GO:0046823 12133 54 42 1 343 3 3 false 0.40283049475389054 0.40283049475389054 2.3530708460848664E-64 inactivation_of_MAPK_activity GO:0000188 12133 25 42 1 62 1 1 false 0.4032258064516162 0.4032258064516162 6.784005293429779E-18 regulation_of_protein_kinase_activity GO:0045859 12133 621 42 4 1169 6 3 false 0.40367069584855936 0.40367069584855936 0.0 transmission_of_nerve_impulse GO:0019226 12133 586 42 3 4105 16 3 false 0.4053740637343272 0.4053740637343272 0.0 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 42 5 1304 5 1 false 0.40559467300726026 0.40559467300726026 1.004636319027547E-252 appendage_development GO:0048736 12133 114 42 1 3347 15 3 false 0.40602515673523343 0.40602515673523343 2.7546219462070674E-215 positive_regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032436 12133 35 42 1 288 4 4 false 0.4061872551922686 0.4061872551922686 7.428075320192054E-46 nucleoplasm GO:0005654 12133 1443 42 12 2767 21 2 false 0.40650128794228474 0.40650128794228474 0.0 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 42 9 4878 32 5 false 0.40688528446584893 0.40688528446584893 0.0 pigment_granule GO:0048770 12133 87 42 1 712 4 1 false 0.40695334576713815 0.40695334576713815 3.4546414966613156E-114 lipid_biosynthetic_process GO:0008610 12133 360 42 3 4386 28 2 false 0.4069959417146599 0.4069959417146599 0.0 receptor_activity GO:0004872 12133 790 42 4 10257 42 1 false 0.4073285611686954 0.4073285611686954 0.0 leukocyte_differentiation GO:0002521 12133 299 42 2 2177 10 2 false 0.40860804465580813 0.40860804465580813 0.0 regulation_of_lipid_biosynthetic_process GO:0046890 12133 85 42 1 3279 20 3 false 0.4095304590436364 0.4095304590436364 1.2266874982723732E-170 positive_regulation_of_organelle_organization GO:0010638 12133 217 42 2 2191 14 3 false 0.4107754662646887 0.4107754662646887 1.6765812392172608E-306 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 42 1 22 2 1 false 0.4112554112554107 0.4112554112554107 3.79737221842484E-5 type_I_transforming_growth_factor_beta_receptor_binding GO:0034713 12133 7 42 1 17 1 1 false 0.41176470588235337 0.41176470588235337 5.141916906622793E-5 nucleoplasm_part GO:0044451 12133 805 42 7 2767 21 2 false 0.41289111138213563 0.41289111138213563 0.0 nuclear_lumen GO:0031981 12133 2490 42 19 3186 23 2 false 0.41327823503518635 0.41327823503518635 0.0 cellular_component GO:0005575 12133 10701 42 41 11221 42 1 false 0.41400005395392103 0.41400005395392103 0.0 reactive_oxygen_species_metabolic_process GO:0072593 12133 104 42 1 7256 37 1 false 0.414621244460339 0.414621244460339 6.643362394593683E-236 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 42 1 6380 25 3 false 0.4147364203688934 0.4147364203688934 2.5067679665083333E-283 basal_RNA_polymerase_II_transcription_machinery_binding GO:0001099 12133 76 42 1 464 3 1 false 0.41603200181074573 0.41603200181074573 2.7883330382309735E-89 dendrite_development GO:0016358 12133 111 42 1 3152 15 3 false 0.4166577370981607 0.4166577370981607 5.679983906241444E-208 negative_regulation_of_developmental_process GO:0051093 12133 463 42 3 4566 23 3 false 0.4172453089711363 0.4172453089711363 0.0 regulation_of_lyase_activity GO:0051339 12133 117 42 1 1793 8 2 false 0.41779627830559596 0.41779627830559596 4.0773224530305873E-187 regulation_of_cell_motility GO:2000145 12133 370 42 2 831 3 3 false 0.4181004063108299 0.4181004063108299 3.695619588048616E-247 negative_regulation_of_cell_activation GO:0050866 12133 88 42 1 2815 17 3 false 0.4181181987034548 0.4181181987034548 2.046439547950988E-169 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 42 3 1192 9 2 false 0.41819248777999707 0.41819248777999707 5.168872172755415E-294 cellular_response_to_hypoxia GO:0071456 12133 79 42 1 1210 8 3 false 0.4182814864782157 0.4182814864782157 3.484581288071841E-126 mitochondrial_membrane GO:0031966 12133 359 42 2 1810 7 3 false 0.4188613367288614 0.4188613367288614 0.0 meiosis_I GO:0007127 12133 55 42 1 1243 12 3 false 0.420478741787758 0.420478741787758 2.718753320211584E-97 negative_regulation_of_protein_complex_assembly GO:0031333 12133 63 42 1 954 8 3 false 0.4222653171014327 0.4222653171014327 3.124938390294621E-100 calcium_ion_transmembrane_transporter_activity GO:0015085 12133 117 42 1 277 1 3 false 0.42238267148015535 0.42238267148015535 2.4235660306174516E-81 tissue_migration GO:0090130 12133 131 42 1 4095 17 1 false 0.42525181096063347 0.42525181096063347 4.3202440607580954E-251 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 42 1 389 2 3 false 0.4253703654626078 0.4253703654626078 8.074632425282073E-93 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 42 1 183 1 2 false 0.4262295081967117 0.4262295081967117 1.0111677973178846E-53 organelle_envelope GO:0031967 12133 629 42 4 7756 41 3 false 0.428307517616807 0.428307517616807 0.0 cellular_response_to_abiotic_stimulus GO:0071214 12133 140 42 1 4330 17 2 false 0.42866977772551207 0.42866977772551207 1.0171050636125265E-267 regulation_of_cyclase_activity GO:0031279 12133 115 42 1 1700 8 2 false 0.42967530018762956 0.42967530018762956 4.764508019192963E-182 sulfur_compound_binding GO:1901681 12133 122 42 1 8962 41 1 false 0.43063565199158654 0.43063565199158654 1.4469175526653028E-279 calcium_channel_activity GO:0005262 12133 104 42 1 241 1 3 false 0.4315352697096034 0.4315352697096034 5.2662088963328235E-71 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 42 2 1376 12 3 false 0.43154101330228006 0.43154101330228006 2.059495184181185E-218 basal_transcription_machinery_binding GO:0001098 12133 464 42 3 6397 33 1 false 0.4326884802740949 0.4326884802740949 0.0 cell_cycle_process GO:0022402 12133 953 42 5 7541 34 2 false 0.4327499984144252 0.4327499984144252 0.0 cellular_component_biogenesis GO:0044085 12133 1525 42 10 3839 23 1 false 0.4328355471948005 0.4328355471948005 0.0 membrane_depolarization_involved_in_regulation_of_cardiac_muscle_cell_action_potential GO:0086012 12133 10 42 1 23 1 2 false 0.43478260869565266 0.43478260869565266 8.740754466962545E-7 regulation_of_protein_localization_to_nucleus GO:1900180 12133 125 42 1 722 3 3 false 0.4351506961067408 0.4351506961067408 8.18717732691146E-144 negative_regulation_of_signal_transduction GO:0009968 12133 571 42 3 3588 15 5 false 0.4356483726718581 0.4356483726718581 0.0 gland_morphogenesis GO:0022612 12133 105 42 1 2812 15 3 false 0.43576130578594496 0.43576130578594496 5.511647482343512E-194 regulation_of_response_to_DNA_damage_stimulus GO:2001020 12133 80 42 1 741 5 2 false 0.4360977116208743 0.4360977116208743 1.553661553762129E-109 cAMP_biosynthetic_process GO:0006171 12133 124 42 1 284 1 3 false 0.4366197183098948 0.4366197183098948 6.647675853046176E-84 spindle_pole GO:0000922 12133 87 42 1 3232 21 3 false 0.4372036341292698 0.4372036341292698 3.214023535487519E-173 mRNA_stabilization GO:0048255 12133 22 42 2 33 2 2 false 0.43750000000000067 0.43750000000000067 5.166978132108427E-9 nuclear_body GO:0016604 12133 272 42 3 805 7 1 false 0.4398898890329874 0.4398898890329874 8.12188174084084E-223 double-strand_break_repair_via_homologous_recombination GO:0000724 12133 48 42 1 109 1 2 false 0.4403669724770689 0.4403669724770689 4.364037891784993E-32 metallopeptidase_activity GO:0008237 12133 103 42 1 586 3 1 false 0.44066381473343075 0.44066381473343075 1.108136232226785E-117 ameboidal_cell_migration GO:0001667 12133 185 42 1 734 2 1 false 0.4408184051951548 0.4408184051951548 3.1688746703355204E-179 response_to_topologically_incorrect_protein GO:0035966 12133 133 42 1 3273 14 2 false 0.441197796767005 0.441197796767005 7.334457285081863E-241 mesenchymal_cell_differentiation GO:0048762 12133 118 42 2 256 3 2 false 0.44129588351081417 0.44129588351081417 3.77778946596228E-76 regulation_of_locomotion GO:0040012 12133 398 42 2 6714 25 2 false 0.44134396056220715 0.44134396056220715 0.0 spindle GO:0005819 12133 221 42 2 4762 32 4 false 0.4415515670557765 0.4415515670557765 0.0 appendage_morphogenesis GO:0035107 12133 107 42 1 2812 15 3 false 0.4419982370386593 0.4419982370386593 8.534046950129346E-197 regulation_of_cell_morphogenesis GO:0022604 12133 267 42 2 1647 9 3 false 0.44231543595788025 0.44231543595788025 3.9027101E-316 rhythmic_process GO:0048511 12133 148 42 1 10446 41 1 false 0.4435498414860072 0.4435498414860072 0.0 regulation_of_ligase_activity GO:0051340 12133 98 42 1 2061 12 2 false 0.4435697641825136 0.4435697641825136 1.6310105681359867E-170 positive_regulation_of_cyclic_nucleotide_metabolic_process GO:0030801 12133 80 42 1 180 1 3 false 0.44444444444442294 0.44444444444442294 3.3247573319336413E-53 protein_deacetylase_activity GO:0033558 12133 28 42 1 63 1 2 false 0.44444444444444187 0.44444444444444187 1.5890462849475085E-18 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 42 1 1198 9 4 false 0.4467314217374293 0.4467314217374293 2.335035261625238E-122 DNA-dependent_transcription,_termination GO:0006353 12133 80 42 1 2751 20 2 false 0.4469514813630655 0.4469514813630655 1.5820458311792457E-156 RNA_polyadenylation GO:0043631 12133 25 42 1 98 2 1 false 0.44708605091520026 0.44708605091520026 7.35522495115787E-24 negative_regulation_of_transcription_factor_import_into_nucleus GO:0042992 12133 34 42 1 76 1 3 false 0.4473684210526281 0.4473684210526281 2.199973770519916E-22 female_gonad_development GO:0008585 12133 73 42 1 163 1 2 false 0.44785276073619185 0.44785276073619185 3.313368928641239E-48 proteolysis GO:0006508 12133 732 42 6 3431 25 1 false 0.4490644700975549 0.4490644700975549 0.0 carboxylic_acid_binding GO:0031406 12133 186 42 1 2280 7 1 false 0.44927245631778867 0.44927245631778867 4.771798836819993E-279 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 42 1 676 7 2 false 0.4494314745448623 0.4494314745448623 2.737610529852072E-82 chromosome,_centromeric_region GO:0000775 12133 148 42 2 512 5 1 false 0.44947894375636493 0.44947894375636493 5.05623540709124E-133 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 42 4 7293 35 3 false 0.4501432009647504 0.4501432009647504 0.0 response_to_hormone_stimulus GO:0009725 12133 611 42 3 1784 7 2 false 0.4504817988636074 0.4504817988636074 0.0 negative_regulation_of_MAP_kinase_activity GO:0043407 12133 62 42 1 343 3 4 false 0.4512254662630904 0.4512254662630904 7.269028156110723E-70 intermediate_filament_cytoskeleton GO:0045111 12133 136 42 1 1430 6 1 false 0.45158497068577264 0.45158497068577264 2.0803615427594252E-194 cytoplasmic_part GO:0044444 12133 5117 42 24 9083 41 2 false 0.4521995286500048 0.4521995286500048 0.0 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 42 2 217 3 1 false 0.45491432381900665 0.45491432381900665 1.2933579260360868E-64 cellular_response_to_hydrogen_peroxide GO:0070301 12133 46 42 1 101 1 2 false 0.45544554455445335 0.45544554455445335 7.411828733171962E-30 transferase_activity,_transferring_one-carbon_groups GO:0016741 12133 130 42 1 1779 8 1 false 0.45572648097350626 0.45572648097350626 2.4341608753326182E-201 regulation_of_multicellular_organismal_development GO:2000026 12133 953 42 5 3481 16 3 false 0.45623144747977284 0.45623144747977284 0.0 chromosome GO:0005694 12133 592 42 5 3226 24 1 false 0.45744520230504965 0.45744520230504965 0.0 response_to_UV GO:0009411 12133 92 42 1 201 1 1 false 0.4577114427860681 0.4577114427860681 1.1329357256666295E-59 negative_regulation_of_protein_transport GO:0051224 12133 90 42 1 1225 8 3 false 0.45788966764896427 0.45788966764896427 4.959816028960601E-139 positive_regulation_of_cAMP_metabolic_process GO:0030816 12133 71 42 1 155 1 4 false 0.4580645161290261 0.4580645161290261 5.885583975701031E-46 signaling GO:0023052 12133 3878 42 16 10446 41 1 false 0.4585784208160141 0.4585784208160141 0.0 negative_regulation_of_cellular_component_movement GO:0051271 12133 114 42 1 3032 16 3 false 0.4592163013328964 0.4592163013328964 2.6462769841807196E-210 DNA_insertion_or_deletion_binding GO:0032135 12133 6 42 1 13 1 1 false 0.4615384615384619 0.4615384615384619 5.827505827505821E-4 U5_snRNP GO:0005682 12133 80 42 5 93 5 1 false 0.4625634506656407 0.4625634506656407 3.852654648545616E-16 embryo_development GO:0009790 12133 768 42 4 3347 15 3 false 0.46313008316597837 0.46313008316597837 0.0 regulation_of_lymphocyte_proliferation GO:0050670 12133 127 42 1 274 1 3 false 0.4635036496350203 0.4635036496350203 1.4165790688232408E-81 cytokine_receptor_binding GO:0005126 12133 172 42 1 918 3 1 false 0.46375834687793493 0.46375834687793493 1.4338329427110724E-191 phosphatidylinositol_phosphorylation GO:0046854 12133 64 42 1 138 1 2 false 0.4637681159420311 0.4637681159420311 6.067366163410429E-41 positive_regulation_of_nucleotide_biosynthetic_process GO:0030810 12133 77 42 1 1402 11 4 false 0.4640166405827142 0.4640166405827142 6.104501177954134E-129 ovarian_follicle_development GO:0001541 12133 39 42 1 84 1 2 false 0.4642857142857246 0.4642857142857246 7.362290770837602E-25 nuclear_export GO:0051168 12133 116 42 2 688 9 2 false 0.4646663908781877 0.4646663908781877 6.892155989004194E-135 regulation_of_neuron_apoptotic_process GO:0043523 12133 143 42 2 1030 11 3 false 0.4650041192360446 0.4650041192360446 1.751953609038846E-179 cellular_component_assembly GO:0022607 12133 1392 42 9 3836 23 2 false 0.46550401025497257 0.46550401025497257 0.0 response_to_hydrogen_peroxide GO:0042542 12133 79 42 1 292 2 2 false 0.46857788447959337 0.46857788447959337 1.759985381548074E-73 nuclear_envelope GO:0005635 12133 258 42 2 3962 24 3 false 0.4696976961853889 0.4696976961853889 0.0 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 42 1 134 1 2 false 0.47014925373133665 0.47014925373133665 8.460684206886756E-40 regulation_of_body_fluid_levels GO:0050878 12133 527 42 3 4595 22 2 false 0.4704810735163274 0.4704810735163274 0.0 carbohydrate_derivative_binding GO:0097367 12133 138 42 1 8962 41 1 false 0.47148221062438245 0.47148221062438245 7.388129485723004E-309 negative_regulation_of_intracellular_transport GO:0032387 12133 72 42 1 1281 11 3 false 0.4721237403122137 0.4721237403122137 8.445033635932749E-120 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 42 1 278 2 3 false 0.47274238371037897 0.47274238371037897 2.8121052478162137E-70 neuron_death GO:0070997 12133 170 42 2 1525 14 1 false 0.47383219130365406 0.47383219130365406 9.045134214386945E-231 regulation_of_neuron_death GO:1901214 12133 151 42 2 1070 11 2 false 0.474074565590584 0.474074565590584 2.12628458479716E-188 membrane_lipid_metabolic_process GO:0006643 12133 90 42 1 606 4 1 false 0.47524671595199663 0.47524671595199663 5.920711661089953E-110 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 42 1 2180 12 2 false 0.4759680873996091 0.4759680873996091 1.341003616993524E-193 cellular_membrane_organization GO:0016044 12133 784 42 4 7541 34 2 false 0.4773542253246001 0.4773542253246001 0.0 positive_regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030804 12133 75 42 1 157 1 4 false 0.4777070063694132 0.4777070063694132 1.0054402594300752E-46 mRNA_polyadenylation GO:0006378 12133 24 42 1 87 2 2 false 0.47794707297515227 0.47794707297515227 5.836090149000628E-22 regulation_of_primary_metabolic_process GO:0080090 12133 3921 42 20 7507 37 2 false 0.4780813229206633 0.4780813229206633 0.0 glycerophospholipid_metabolic_process GO:0006650 12133 189 42 2 273 2 2 false 0.47850678733026264 0.47850678733026264 1.2595264627170145E-72 regulation_of_cellular_component_movement GO:0051270 12133 412 42 2 6475 25 3 false 0.47870397087821465 0.47870397087821465 0.0 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 42 3 2896 15 3 false 0.48024148942283873 0.48024148942283873 0.0 negative_regulation_of_signaling GO:0023057 12133 597 42 3 4884 21 3 false 0.4828235099235195 0.4828235099235195 0.0 positive_regulation_of_cell_adhesion GO:0045785 12133 114 42 1 3174 18 3 false 0.4832526993200828 0.4832526993200828 1.3009596629773978E-212 negative_regulation_of_locomotion GO:0040013 12133 129 42 1 3189 16 3 false 0.48432118381270495 0.48432118381270495 7.329512152442089E-234 mitochondrion GO:0005739 12133 1138 42 6 8213 40 2 false 0.48538474266618975 0.48538474266618975 0.0 mRNA_3'-end_processing GO:0031124 12133 86 42 2 386 7 2 false 0.48614933203046184 0.48614933203046184 2.4694341980396157E-88 histone_mRNA_catabolic_process GO:0071044 12133 13 42 1 186 9 2 false 0.4868137815457034 0.4868137815457034 2.998872478873387E-20 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 42 8 1225 8 2 false 0.48721521817905944 0.48721521817905944 5.928244845001387E-155 Rho_protein_signal_transduction GO:0007266 12133 178 42 1 365 1 1 false 0.4876712328767119 0.4876712328767119 3.561371803691081E-109 regulation_of_protein_import_into_nucleus GO:0042306 12133 121 42 1 248 1 4 false 0.48790322580649104 0.48790322580649104 4.6955049394038436E-74 negative_regulation_of_cell_communication GO:0010648 12133 599 42 3 4860 21 3 false 0.4886135991644433 0.4886135991644433 0.0 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 42 3 5830 22 3 false 0.4892392259780403 0.4892392259780403 0.0 BMP_signaling_pathway GO:0030509 12133 83 42 1 1276 10 2 false 0.4908724318499221 0.4908724318499221 9.874891335860256E-133 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 42 11 6129 37 3 false 0.4918440502863686 0.4918440502863686 0.0 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 42 1 130 1 2 false 0.4923076923076922 0.4923076923076922 1.0680656075518395E-38 regulation_of_cellular_ketone_metabolic_process GO:0010565 12133 133 42 1 3992 20 2 false 0.49304413729324786 0.49304413729324786 1.512735013638228E-252 negative_regulation_of_translation GO:0017148 12133 61 42 1 1470 16 4 false 0.49423058008005627 0.49423058008005627 1.1152524521517982E-109 cytokine_metabolic_process GO:0042107 12133 92 42 1 3431 25 1 false 0.49436032004623937 0.49436032004623937 2.347983592216771E-183 development_of_primary_female_sexual_characteristics GO:0046545 12133 88 42 1 178 1 2 false 0.49438202247194724 0.49438202247194724 4.419703906638309E-53 regulation_of_leukocyte_proliferation GO:0070663 12133 131 42 1 1029 5 2 false 0.4945395446150963 0.4945395446150963 1.1421072529969205E-169 interspecies_interaction_between_organisms GO:0044419 12133 417 42 4 1180 10 1 false 0.4955776145099482 0.4955776145099482 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 42 3 701 4 2 false 0.49579958057426765 0.49579958057426765 1.5434745144062482E-202 negative_regulation_of_cell_growth GO:0030308 12133 117 42 1 2621 15 4 false 0.49685456908715575 0.49685456908715575 6.020174158767381E-207 protein_transport GO:0015031 12133 1099 42 8 1627 11 2 false 0.4976984898251995 0.4976984898251995 0.0 regulation_of_Rho_protein_signal_transduction GO:0035023 12133 149 42 1 299 1 2 false 0.4983277591973189 0.4983277591973189 2.1331125641940734E-89 cation_channel_activity GO:0005261 12133 216 42 1 433 1 2 false 0.4988452655890016 0.4988452655890016 1.1777872542675005E-129 metal_ion_transmembrane_transporter_activity GO:0046873 12133 263 42 1 527 1 2 false 0.49905123339657426 0.49905123339657426 6.55805140577772E-158 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 42 8 6103 37 3 false 0.4995661256143036 0.4995661256143036 0.0 ventricular_septum_morphogenesis GO:0060412 12133 24 42 1 48 1 2 false 0.49999999999999906 0.49999999999999906 3.101005612159816E-14 dinucleotide_insertion_or_deletion_binding GO:0032139 12133 3 42 1 6 1 1 false 0.4999999999999997 0.4999999999999997 0.04999999999999996 regulation_of_leukocyte_activation GO:0002694 12133 278 42 1 948 2 3 false 0.500721799687286 0.500721799687286 2.7935655578419027E-248 kinetochore GO:0000776 12133 102 42 1 4762 32 4 false 0.5010072259840548 0.5010072259840548 2.0967772168942355E-213 neuron_projection_development GO:0031175 12133 575 42 2 812 2 2 false 0.5011905268082553 0.5011905268082553 3.771933680434825E-212 steroid_biosynthetic_process GO:0006694 12133 98 42 1 3573 25 3 false 0.5022495411185848 0.5022495411185848 2.291833143174281E-194 cellular_response_to_organic_substance GO:0071310 12133 1347 42 6 1979 8 2 false 0.5027668224817607 0.5027668224817607 0.0 RNA_3'-end_processing GO:0031123 12133 98 42 2 601 10 1 false 0.5042120832274184 0.5042120832274184 1.9130441150898719E-115 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 42 3 1379 6 2 false 0.5043954659273013 0.5043954659273013 0.0 cysteine-type_peptidase_activity GO:0008234 12133 295 42 2 586 3 1 false 0.505128145188445 0.505128145188445 1.2148857586981575E-175 multicellular_organismal_process GO:0032501 12133 4223 42 17 10446 41 1 false 0.5054557001896789 0.5054557001896789 0.0 cytoplasmic_vesicle GO:0031410 12133 764 42 4 8540 41 3 false 0.5060112976910804 0.5060112976910804 0.0 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 42 21 6638 37 2 false 0.5062392761937733 0.5062392761937733 0.0 Wnt_receptor_signaling_pathway GO:0016055 12133 260 42 1 1975 5 1 false 0.5066544600176255 0.5066544600176255 0.0 negative_regulation_of_immune_system_process GO:0002683 12133 144 42 1 3524 17 3 false 0.5088012338833376 0.5088012338833376 1.8096661454151343E-260 anatomical_structure_development GO:0048856 12133 3099 42 15 3447 16 1 false 0.5090772038767903 0.5090772038767903 0.0 nucleotide_binding GO:0000166 12133 1997 42 13 2103 13 2 false 0.5095018929375557 0.5095018929375557 1.0169073992212018E-181 negative_regulation_of_intracellular_protein_transport GO:0090317 12133 59 42 1 695 8 4 false 0.5100598408879491 0.5100598408879491 3.676422199192608E-87 B_cell_differentiation GO:0030183 12133 78 42 1 260 2 2 false 0.51081081081084 0.51081081081084 1.9566405478463094E-68 cellular_chemical_homeostasis GO:0055082 12133 525 42 2 734 2 2 false 0.5113173810732686 0.5113173810732686 1.1478565010718528E-189 mitochondrial_matrix GO:0005759 12133 236 42 2 3218 23 2 false 0.5115185292997266 0.5115185292997266 0.0 nucleotide-excision_repair GO:0006289 12133 78 42 1 368 3 1 false 0.5116925389541156 0.5116925389541156 5.504322769590107E-82 cellular_amino_acid_metabolic_process GO:0006520 12133 337 42 2 7342 37 3 false 0.5118553785057895 0.5118553785057895 0.0 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_linear_amides GO:0016811 12133 42 42 1 82 1 1 false 0.5121951219512042 0.5121951219512042 2.4115523257823617E-24 chemotaxis GO:0006935 12133 488 42 2 2369 8 2 false 0.5144175970906578 0.5144175970906578 0.0 MAPK_cascade GO:0000165 12133 502 42 3 806 4 1 false 0.5148409174195878 0.5148409174195878 3.7900857366173457E-231 positive_regulation_of_cAMP_biosynthetic_process GO:0030819 12133 69 42 1 134 1 5 false 0.5149253731343213 0.5149253731343213 7.0817799397690005E-40 tube_development GO:0035295 12133 371 42 2 3304 15 2 false 0.5150514376340254 0.5150514376340254 0.0 cation_binding GO:0043169 12133 2758 42 11 4448 17 1 false 0.516263503180616 0.516263503180616 0.0 regulation_of_transcription_factor_import_into_nucleus GO:0042990 12133 63 42 1 122 1 2 false 0.5163934426229579 0.5163934426229579 2.784334919854664E-36 neuron_projection GO:0043005 12133 534 42 2 1043 3 2 false 0.5179908112521974 0.5179908112521974 5.7946905775E-313 response_to_endoplasmic_reticulum_stress GO:0034976 12133 111 42 1 1124 7 1 false 0.5180419857093981 0.5180419857093981 1.1256089410717349E-156 histone_mRNA_metabolic_process GO:0008334 12133 27 42 1 573 15 1 false 0.519641458945738 0.519641458945738 6.871324608301151E-47 GTPase_binding GO:0051020 12133 137 42 1 1005 5 1 false 0.5201736896141022 0.5201736896141022 4.2154504665352884E-173 chromatin_modification GO:0016568 12133 458 42 4 539 4 1 false 0.5202927821931725 0.5202927821931725 1.802023694196357E-98 cation_transmembrane_transporter_activity GO:0008324 12133 365 42 1 701 1 2 false 0.5206847360912653 0.5206847360912653 5.744660517109641E-210 divalent_metal_ion_transport GO:0070838 12133 237 42 1 455 1 2 false 0.5208791208791013 0.5208791208791013 4.2718300435394164E-136 negative_regulation_of_ligase_activity GO:0051352 12133 71 42 1 1003 10 3 false 0.521749277834973 0.521749277834973 8.698138776450475E-111 blood_coagulation GO:0007596 12133 443 42 3 550 3 3 false 0.5218539710855767 0.5218539710855767 4.662213706291943E-117 negative_regulation_of_cell_cycle GO:0045786 12133 298 42 2 3131 18 3 false 0.5224458399515409 0.5224458399515409 0.0 RNA_polymerase_II_transcription_regulatory_region_sequence-specific_DNA_binding_transcription_factor_activity_involved_in_positive_regulation_of_transcription GO:0001228 12133 65 42 1 740 8 2 false 0.5224897328487443 0.5224897328487443 4.721569359537849E-95 DNA_damage_checkpoint GO:0000077 12133 126 42 1 574 3 2 false 0.5252577839731293 0.5252577839731293 1.5833464450994651E-130 cytoplasmic_sequestering_of_transcription_factor GO:0042994 12133 20 42 1 38 1 2 false 0.5263157894736858 0.5263157894736858 2.978140395000689E-11 protein_serine/threonine_kinase_activity GO:0004674 12133 709 42 4 1014 5 1 false 0.5263904827414219 0.5263904827414219 1.8231541307779663E-268 glycerolipid_metabolic_process GO:0046486 12133 243 42 2 606 4 1 false 0.5268003957658728 0.5268003957658728 1.781632444658852E-176 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 42 4 1730 10 2 false 0.527731916103746 0.527731916103746 0.0 regulation_of_action_potential GO:0001508 12133 114 42 1 216 1 1 false 0.5277777777777679 0.5277777777777679 2.440510173476933E-64 regulation_of_nervous_system_development GO:0051960 12133 381 42 2 1805 8 2 false 0.5291249534554102 0.5291249534554102 0.0 mRNA_3'-UTR_binding GO:0003730 12133 20 42 1 91 3 1 false 0.5295303946989349 0.5295303946989349 1.5304206568397613E-20 blood_vessel_endothelial_cell_migration GO:0043534 12133 53 42 1 100 1 1 false 0.5300000000000151 0.5300000000000151 1.1846448146925151E-29 tRNA_metabolic_process GO:0006399 12133 104 42 2 258 4 1 false 0.5308563704641639 0.5308563704641639 5.594663773224907E-75 cellular_ketone_metabolic_process GO:0042180 12133 155 42 1 7667 37 3 false 0.5311505880596671 0.5311505880596671 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 42 1 86 2 2 false 0.5318741450068484 0.5318741450068484 6.233113581740502E-23 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 42 1 1679 12 3 false 0.5333995144005744 0.5333995144005744 1.5952227787322578E-167 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 42 2 3842 16 3 false 0.5341298029926678 0.5341298029926678 0.0 phosphorus-oxygen_lyase_activity GO:0016849 12133 123 42 1 230 1 1 false 0.5347826086956033 0.5347826086956033 1.920154677041111E-68 regulation_of_neurogenesis GO:0050767 12133 344 42 2 1039 5 4 false 0.534961347183373 0.534961347183373 1.1807712079388562E-285 sequence-specific_DNA_binding_RNA_polymerase_II_transcription_factor_activity GO:0000981 12133 226 42 2 1815 14 4 false 0.5359440081986975 0.5359440081986975 1.998611403782172E-295 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 42 6 6622 25 1 false 0.5364740481069162 0.5364740481069162 0.0 cell-substrate_junction GO:0030055 12133 133 42 1 588 3 1 false 0.5373501686549852 0.5373501686549852 7.571970094553597E-136 zinc_ion_binding GO:0008270 12133 1314 42 6 1457 6 1 false 0.537436307924549 0.537436307924549 2.194714234876188E-202 regulation_of_protein_stability GO:0031647 12133 99 42 1 2240 17 2 false 0.5375746659315168 0.5375746659315168 1.7785498552391114E-175 actin_binding GO:0003779 12133 299 42 1 556 1 1 false 0.5377697841725919 0.5377697841725919 6.115970052445393E-166 ribose_phosphate_biosynthetic_process GO:0046390 12133 279 42 1 1586 4 3 false 0.5391725656674378 0.5391725656674378 1.5665E-319 protein_kinase_activity GO:0004672 12133 1014 42 5 1347 6 3 false 0.540344995051022 0.540344995051022 0.0 mesenchymal_cell_development GO:0014031 12133 106 42 2 201 3 2 false 0.541209780244498 0.541209780244498 7.469742798600782E-60 negative_regulation_of_cell_proliferation GO:0008285 12133 455 42 3 2949 18 3 false 0.5412806676088265 0.5412806676088265 0.0 cellular_response_to_laminar_fluid_shear_stress GO:0071499 12133 5 42 1 16 2 2 false 0.5416666666666651 0.5416666666666651 2.2893772893772823E-4 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 42 1 202 7 1 false 0.5419318356902139 0.5419318356902139 5.801734415928739E-29 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 42 1 116 1 3 false 0.5431034482758698 0.5431034482758698 2.4978330889301296E-34 cellular_developmental_process GO:0048869 12133 2267 42 10 7817 34 2 false 0.5437206082959525 0.5437206082959525 0.0 identical_protein_binding GO:0042802 12133 743 42 4 6397 33 1 false 0.5441112279111664 0.5441112279111664 0.0 ceramide_metabolic_process GO:0006672 12133 37 42 1 68 1 1 false 0.5441176470588207 0.5441176470588207 4.563528183708786E-20 positive_regulation_of_gene_expression GO:0010628 12133 1008 42 8 4103 32 3 false 0.5454471599213921 0.5454471599213921 0.0 MutLalpha_complex_binding GO:0032405 12133 6 42 1 11 1 1 false 0.5454545454545465 0.5454545454545465 0.002164502164502163 nuclease_activity GO:0004518 12133 197 42 1 853 3 2 false 0.5456351761429903 0.5456351761429903 1.9441890942275812E-199 ventricular_cardiac_muscle_tissue_morphogenesis GO:0055010 12133 35 42 1 64 1 3 false 0.5468749999999926 0.5468749999999926 7.200365978668321E-19 cardiac_ventricle_morphogenesis GO:0003208 12133 51 42 1 93 1 2 false 0.5483870967741857 0.5483870967741857 1.883975738002296E-27 regulation_of_gene_expression,_epigenetic GO:0040029 12133 120 42 1 2935 19 1 false 0.5487135538672276 0.5487135538672276 6.075348180017095E-217 MAP_kinase_activity GO:0004707 12133 277 42 2 520 3 2 false 0.5490629039759068 0.5490629039759068 2.5282679507054518E-155 RNA_polymerase_II_transcription_factor_binding_transcription_factor_activity GO:0001076 12133 88 42 1 1484 13 4 false 0.549782473875084 0.549782473875084 2.1138779413162717E-144 positive_regulation_of_transferase_activity GO:0051347 12133 445 42 2 2275 9 3 false 0.5507914488302682 0.5507914488302682 0.0 rRNA_metabolic_process GO:0016072 12133 107 42 2 258 4 1 false 0.5508990402784166 0.5508990402784166 1.860360860420455E-75 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 42 1 1813 11 1 false 0.5511915609495245 0.5511915609495245 4.219154160176784E-199 protein-DNA_complex_assembly GO:0065004 12133 126 42 1 538 3 2 false 0.5516661361012092 0.5516661361012092 1.6410350721824938E-126 gene_silencing_by_RNA GO:0031047 12133 48 42 1 87 1 1 false 0.5517241379310461 0.5517241379310461 1.2013602639031232E-25 activation_of_MAPK_activity GO:0000187 12133 158 42 1 286 1 2 false 0.5524475524475345 0.5524475524475345 8.207976102051858E-85 gonad_development GO:0008406 12133 150 42 1 2876 15 4 false 0.5531322094248736 0.5531322094248736 4.529833702866928E-255 G1_DNA_damage_checkpoint GO:0044783 12133 70 42 1 126 1 1 false 0.5555555555555676 0.5555555555555676 3.590272155218709E-37 kinase_activity GO:0016301 12133 1174 42 5 1546 6 2 false 0.5561665966805087 0.5561665966805087 0.0 cell_junction_organization GO:0034330 12133 181 42 1 7663 34 2 false 0.5571359377987468 0.5571359377987468 0.0 response_to_ionizing_radiation GO:0010212 12133 98 42 1 293 2 1 false 0.5578334658002119 0.5578334658002119 1.6270830108212225E-80 RNA_polymerase_II_core_promoter_proximal_region_sequence-specific_DNA_binding_transcription_factor_activity_involved_in_negative_regulation_of_transcription GO:0001078 12133 29 42 1 87 2 2 false 0.5581395348837324 0.5581395348837324 9.860292671679696E-24 negative_regulation_of_MAPK_cascade GO:0043409 12133 99 42 1 537 4 3 false 0.558534083627083 0.558534083627083 7.769471694565091E-111 passive_transmembrane_transporter_activity GO:0022803 12133 304 42 1 544 1 1 false 0.5588235294118147 0.5588235294118147 2.1953421087848878E-161 adherens_junction_organization GO:0034332 12133 85 42 1 152 1 1 false 0.5592105263157607 0.5592105263157607 7.834980933972919E-45 RNA_polymerase_II_regulatory_region_DNA_binding GO:0001012 12133 260 42 2 1169 8 1 false 0.5611601007039169 0.5611601007039169 3.195774442512401E-268 cyclic_purine_nucleotide_metabolic_process GO:0052652 12133 151 42 1 269 1 2 false 0.5613382899628113 0.5613382899628113 1.6379011785432358E-79 regulation_of_cellular_localization GO:0060341 12133 603 42 3 6869 33 3 false 0.5633665875471126 0.5633665875471126 0.0 monosaccharide_metabolic_process GO:0005996 12133 217 42 1 385 1 1 false 0.5636363636363345 0.5636363636363345 7.061110236111427E-114 regulation_of_nucleotide_biosynthetic_process GO:0030808 12133 146 42 1 3406 19 3 false 0.5659836954050764 0.5659836954050764 5.390613252169377E-261 regulation_of_cardiac_muscle_contraction GO:0055117 12133 44 42 1 129 2 3 false 0.5675872093023271 0.5675872093023271 1.5054018361547051E-35 substrate-specific_channel_activity GO:0022838 12133 291 42 1 512 1 2 false 0.5683593749999285 0.5683593749999285 2.547694139879492E-151 endoplasmic_reticulum_lumen GO:0005788 12133 125 42 1 3346 22 2 false 0.5684246098948662 0.5684246098948662 5.341455344292604E-231 macromolecule_modification GO:0043412 12133 2461 42 15 6052 37 1 false 0.5685511666979182 0.5685511666979182 0.0 protein_dephosphorylation GO:0006470 12133 146 42 1 2505 14 2 false 0.5695696524447028 0.5695696524447028 5.1980515318736674E-241 small_ribosomal_subunit GO:0015935 12133 60 42 3 132 6 1 false 0.5697909472713992 0.5697909472713992 4.556510204279982E-39 insulin_receptor_signaling_pathway GO:0008286 12133 151 42 1 617 3 2 false 0.5698540302247384 0.5698540302247384 2.0667953594506098E-148 RNA_polymerase_II_regulatory_region_sequence-specific_DNA_binding GO:0000977 12133 257 42 2 1123 8 2 false 0.5787688700601445 0.5787688700601445 1.6391430287111727E-261 lyase_activity GO:0016829 12133 230 42 1 4901 18 1 false 0.579676429705206 0.579676429705206 0.0 development_of_primary_sexual_characteristics GO:0045137 12133 174 42 1 3105 15 3 false 0.5798169332019039 0.5798169332019039 2.1612319791507408E-290 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 42 1 1130 5 2 false 0.5807283681028067 0.5807283681028067 1.9819409219356823E-214 regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032434 12133 57 42 1 227 3 2 false 0.5818538588489612 0.5818538588489612 4.5524072103258975E-55 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 42 2 2776 8 3 false 0.5828987422659726 0.5828987422659726 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 42 18 4972 30 3 false 0.582921438863838 0.582921438863838 0.0 protein-DNA_complex GO:0032993 12133 110 42 1 3462 27 1 false 0.5832025397047598 0.5832025397047598 4.3156565695482125E-211 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 42 1 1663 10 2 false 0.583273575784077 0.583273575784077 7.181952736648417E-207 response_to_peptide GO:1901652 12133 322 42 1 904 2 2 false 0.5857686766829175 0.5857686766829175 7.8711156655671515E-255 nucleoside_phosphate_biosynthetic_process GO:1901293 12133 323 42 2 4156 25 3 false 0.5897193379855485 0.5897193379855485 0.0 transcription-coupled_nucleotide-excision_repair GO:0006283 12133 46 42 1 78 1 1 false 0.589743589743583 0.589743589743583 1.2785885050503116E-22 protein_modification_by_small_protein_removal GO:0070646 12133 77 42 1 645 7 1 false 0.5911258602827024 0.5911258602827024 7.565398504158586E-102 carbohydrate_biosynthetic_process GO:0016051 12133 132 42 1 4212 28 2 false 0.5911689706419541 0.5911689706419541 3.288354819591378E-254 regulation_of_hydrolase_activity GO:0051336 12133 821 42 3 3094 11 2 false 0.5916195026041355 0.5916195026041355 0.0 regulation_of_tyrosine_phosphorylation_of_Stat3_protein GO:0042516 12133 29 42 1 49 1 2 false 0.591836734693884 0.591836734693884 3.536377094612393E-14 nuclear_chromosome_part GO:0044454 12133 244 42 2 2878 23 3 false 0.5929680790802492 0.5929680790802492 0.0 nucleoside_phosphate_binding GO:1901265 12133 1998 42 13 4407 29 2 false 0.5933709406094857 0.5933709406094857 0.0 sex_differentiation GO:0007548 12133 202 42 1 340 1 1 false 0.5941176470587681 0.5941176470587681 4.342696063294865E-99 regulation_of_homeostatic_process GO:0032844 12133 239 42 1 6742 25 2 false 0.5950390419552565 0.5950390419552565 0.0 muscle_tissue_development GO:0060537 12133 295 42 1 1132 3 1 false 0.5961400979081191 0.5961400979081191 3.412889797328503E-281 DNA_alkylation GO:0006305 12133 37 42 1 62 1 1 false 0.5967741935483936 0.5967741935483936 6.784005293429779E-18 renal_system_development GO:0072001 12133 196 42 1 2686 12 2 false 0.5979523152872872 0.5979523152872872 5.871867151923005E-304 cell_differentiation GO:0030154 12133 2154 42 10 2267 10 1 false 0.5990847135452143 0.5990847135452143 2.602261335719434E-194 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 42 1 3297 19 3 false 0.602892785791233 0.602892785791233 4.623981712175632E-272 blood_vessel_morphogenesis GO:0048514 12133 368 42 2 2812 15 3 false 0.6031756633880558 0.6031756633880558 0.0 regulation_of_neuron_projection_development GO:0010975 12133 182 42 1 686 3 3 false 0.6040581119117614 0.6040581119117614 1.2648422067158072E-171 ion_channel_activity GO:0005216 12133 286 42 1 473 1 2 false 0.6046511627906472 0.6046511627906472 3.7303800171637374E-137 single-multicellular_organism_process GO:0044707 12133 4095 42 17 8057 34 2 false 0.6058834726488691 0.6058834726488691 0.0 protein_stabilization GO:0050821 12133 60 42 1 99 1 1 false 0.6060606060605888 0.6060606060605888 1.818679918792965E-28 transition_metal_ion_binding GO:0046914 12133 1457 42 6 2699 11 1 false 0.6068822979079436 0.6068822979079436 0.0 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 42 4 1541 13 3 false 0.6074290467370571 0.6074290467370571 0.0 cell_development GO:0048468 12133 1255 42 6 3306 16 4 false 0.6084589188143219 0.6084589188143219 0.0 enzyme_binding GO:0019899 12133 1005 42 5 6397 33 1 false 0.6089806966021429 0.6089806966021429 0.0 cellular_carbohydrate_metabolic_process GO:0044262 12133 183 42 1 7315 37 2 false 0.6092750505029559 0.6092750505029559 0.0 hemostasis GO:0007599 12133 447 42 3 527 3 1 false 0.6096024868920356 0.6096024868920356 7.174896528140087E-97 heart_morphogenesis GO:0003007 12133 162 42 1 774 4 2 false 0.6099254402188514 0.6099254402188514 1.0020458463027537E-171 DNA_metabolic_process GO:0006259 12133 791 42 5 5627 37 2 false 0.6101185722698401 0.6101185722698401 0.0 regulation_of_lipid_metabolic_process GO:0019216 12133 182 42 1 4352 22 2 false 0.6102122378797389 0.6102122378797389 0.0 response_to_corticosteroid_stimulus GO:0031960 12133 102 42 1 272 2 1 false 0.6102398523984609 0.6102398523984609 1.4208784693795558E-77 vasculature_development GO:0001944 12133 441 42 2 2686 12 2 false 0.6103252744660355 0.6103252744660355 0.0 telomere_maintenance_via_recombination GO:0000722 12133 25 42 1 67 2 2 false 0.6105834464043538 0.6105834464043538 5.975508959273711E-19 nuclear_membrane GO:0031965 12133 157 42 1 4084 24 3 false 0.610752334952853 0.610752334952853 2.8056123615014062E-288 regulation_of_molecular_function GO:0065009 12133 2079 42 8 10494 42 2 false 0.6109776141920555 0.6109776141920555 0.0 response_to_organic_cyclic_compound GO:0014070 12133 487 42 2 1783 7 1 false 0.6112560215751466 0.6112560215751466 0.0 positive_regulation_of_kinase_activity GO:0033674 12133 438 42 2 1181 5 3 false 0.6113178869150198 0.6113178869150198 0.0 plasma_membrane GO:0005886 12133 2594 42 10 10252 41 3 false 0.612872023054023 0.612872023054023 0.0 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 42 1 217 1 2 false 0.6129032258063943 0.6129032258063943 2.2668758893633536E-62 protein_acylation GO:0043543 12133 155 42 1 2370 14 1 false 0.6131132356525484 0.6131132356525484 6.767829300235778E-248 aging GO:0007568 12133 170 42 1 2776 15 1 false 0.6134116297308598 0.6134116297308598 5.943091023043611E-277 blood_vessel_development GO:0001568 12133 420 42 2 3152 15 3 false 0.6135915721577792 0.6135915721577792 0.0 leukocyte_proliferation GO:0070661 12133 167 42 1 1316 7 1 false 0.6141325562430944 0.6141325562430944 1.1010684152010674E-216 leukocyte_activation GO:0045321 12133 475 42 2 1729 7 2 false 0.6149648305931559 0.6149648305931559 0.0 negative_regulation_of_growth GO:0045926 12133 169 42 1 2922 16 3 false 0.6154816135147136 0.6154816135147136 1.2080528965902671E-279 ion_homeostasis GO:0050801 12133 532 42 2 677 2 1 false 0.6172637724733726 0.6172637724733726 5.041033537922393E-152 single_organism_signaling GO:0044700 12133 3878 42 16 8052 34 2 false 0.6172845383627998 0.6172845383627998 0.0 covalent_chromatin_modification GO:0016569 12133 312 42 3 458 4 1 false 0.6185434585864209 0.6185434585864209 7.826311589520491E-124 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 42 2 1112 5 4 false 0.6189430084453751 0.6189430084453751 1.302733E-318 Golgi_membrane GO:0000139 12133 322 42 1 1835 5 3 false 0.6193641479048081 0.6193641479048081 0.0 enzyme_regulator_activity GO:0030234 12133 771 42 3 10257 42 3 false 0.6211548324366495 0.6211548324366495 0.0 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 42 1 252 1 2 false 0.6230158730158346 0.6230158730158346 5.925442745937436E-72 cellular_response_to_unfolded_protein GO:0034620 12133 82 42 1 131 1 2 false 0.6259541984732812 0.6259541984732812 3.4132414427749756E-37 regulation_of_Wnt_receptor_signaling_pathway GO:0030111 12133 156 42 1 1668 10 2 false 0.6264542953553371 0.6264542953553371 2.89270864030114E-224 immune_system_process GO:0002376 12133 1618 42 6 10446 41 1 false 0.6265122948553541 0.6265122948553541 0.0 response_to_chemical_stimulus GO:0042221 12133 2369 42 8 5200 18 1 false 0.6270956901628082 0.6270956901628082 0.0 tyrosine_phosphorylation_of_Stat3_protein GO:0042503 12133 32 42 1 51 1 1 false 0.6274509803921535 0.6274509803921535 2.0635800457973343E-14 condensed_chromosome,_centromeric_region GO:0000779 12133 83 42 1 213 2 2 false 0.6286207812914815 0.6286207812914815 2.5305638965409774E-61 regulation_of_epithelial_cell_proliferation GO:0050678 12133 186 42 1 1027 5 2 false 0.6325574391427902 0.6325574391427902 3.094967326597681E-210 vesicle GO:0031982 12133 834 42 4 7980 41 1 false 0.6335768492219185 0.6335768492219185 0.0 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 42 1 1097 8 3 false 0.6336759937540541 0.6336759937540541 8.208279871491876E-172 regulation_of_organelle_organization GO:0033043 12133 519 42 3 2487 15 2 false 0.6345061301527832 0.6345061301527832 0.0 cellular_response_to_peptide GO:1901653 12133 247 42 1 625 2 3 false 0.6346000000000278 0.6346000000000278 2.2359681686760748E-181 dephosphorylation GO:0016311 12133 328 42 1 2776 8 1 false 0.6347858846442663 0.6347858846442663 0.0 reproductive_system_development GO:0061458 12133 216 42 1 2686 12 1 false 0.6351155629070817 0.6351155629070817 0.0 lymphocyte_proliferation GO:0046651 12133 160 42 1 404 2 2 false 0.6358253691373246 0.6358253691373246 3.946230420659752E-117 B_cell_activation GO:0042113 12133 160 42 1 403 2 1 false 0.6370134439465078 0.6370134439465078 6.533922499780693E-117 ribosome_biogenesis GO:0042254 12133 144 42 2 243 3 1 false 0.6378585299747147 0.6378585299747147 8.984879194471426E-71 regulation_of_peptidyl-tyrosine_phosphorylation GO:0050730 12133 150 42 1 812 5 2 false 0.6408359104217414 0.6408359104217414 5.072476466269739E-168 peptidyl-lysine_acetylation GO:0018394 12133 127 42 1 198 1 2 false 0.6414141414141271 0.6414141414141271 1.293028032371008E-55 regulation_of_localization GO:0032879 12133 1242 42 5 7621 33 2 false 0.6435278242492108 0.6435278242492108 0.0 DNA_integrity_checkpoint GO:0031570 12133 130 42 1 202 1 1 false 0.6435643564356409 0.6435643564356409 1.23666756413938E-56 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 42 3 381 5 2 false 0.6436061629461944 0.6436061629461944 4.820433761728018E-112 regulation_of_Ras_protein_signal_transduction GO:0046578 12133 270 42 1 417 1 2 false 0.6474820143884905 0.6474820143884905 7.174398789465976E-117 system_process GO:0003008 12133 1272 42 5 4095 17 1 false 0.647771117271526 0.647771117271526 0.0 tissue_morphogenesis GO:0048729 12133 415 42 2 2931 15 3 false 0.6489051016276942 0.6489051016276942 0.0 peptidyl-tyrosine_phosphorylation GO:0018108 12133 191 42 1 1195 6 2 false 0.6491235026020794 0.6491235026020794 2.9198379950600046E-227 cell_leading_edge GO:0031252 12133 252 42 1 9983 41 1 false 0.6501949170544988 0.6501949170544988 0.0 double-strand_break_repair GO:0006302 12133 109 42 1 368 3 1 false 0.6525777528107215 0.6525777528107215 1.714085470943145E-96 regulation_of_muscle_contraction GO:0006937 12133 96 42 1 234 2 2 false 0.6532408935842693 0.6532408935842693 3.0261009246098835E-68 T_cell_differentiation GO:0030217 12133 140 42 1 341 2 2 false 0.6532689322062997 0.6532689322062997 1.226864280824078E-99 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 42 1 835 4 2 false 0.6534717171170541 0.6534717171170541 8.0742416973675315E-196 positive_regulation_of_signal_transduction GO:0009967 12133 782 42 3 3650 15 5 false 0.6539329200136605 0.6539329200136605 0.0 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 42 5 5447 34 3 false 0.6542969451067595 0.6542969451067595 0.0 regulation_of_muscle_system_process GO:0090257 12133 112 42 1 481 4 2 false 0.654958279488881 0.654958279488881 9.996580757849421E-113 chromatin_assembly_or_disassembly GO:0006333 12133 126 42 1 539 4 1 false 0.6564714549348099 0.6564714549348099 1.2574164838803103E-126 regulation_of_striated_muscle_contraction GO:0006942 12133 52 42 1 126 2 2 false 0.657015873015871 0.657015873015871 1.1247408012389437E-36 nuclear_transport GO:0051169 12133 331 42 3 1148 11 1 false 0.6575082655973548 0.6575082655973548 1.3196682196913852E-298 phosphatase_activity GO:0016791 12133 306 42 1 465 1 2 false 0.6580645161290675 0.6580645161290675 4.9712656169712896E-129 negative_regulation_of_organelle_organization GO:0010639 12133 168 42 1 2125 13 3 false 0.6583035366158483 0.6583035366158483 2.2467097914760192E-254 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 42 1 759 8 3 false 0.6587270243640193 0.6587270243640193 1.1458874617943115E-123 reproductive_structure_development GO:0048608 12133 216 42 1 3110 15 3 false 0.6611760164097862 0.6611760164097862 0.0 brain_development GO:0007420 12133 420 42 2 2904 15 3 false 0.661184987052335 0.661184987052335 0.0 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 42 2 750 5 3 false 0.6614221615928493 0.6614221615928493 3.090255244762607E-218 cell_junction_assembly GO:0034329 12133 159 42 1 1406 9 2 false 0.6615408722629956 0.6615408722629956 9.423437086545545E-215 anterior/posterior_pattern_specification GO:0009952 12133 163 42 1 246 1 1 false 0.6626016260162862 0.6626016260162862 9.328053240584328E-68 nuclear_chromosome GO:0000228 12133 278 42 2 2899 23 3 false 0.6626437765252952 0.6626437765252952 0.0 regulation_of_proteolysis GO:0030162 12133 146 42 1 1822 13 2 false 0.6636387455255744 0.6636387455255744 4.197674460173735E-220 response_to_oxidative_stress GO:0006979 12133 221 42 1 2540 12 1 false 0.6654003120072656 0.6654003120072656 0.0 intrinsic_to_plasma_membrane GO:0031226 12133 826 42 1 2695 3 2 false 0.6666213551460727 0.6666213551460727 0.0 CD95_death-inducing_signaling_complex GO:0031265 12133 4 42 1 6 1 1 false 0.6666666666666662 0.6666666666666662 0.06666666666666664 diadenosine_tetraphosphate_metabolic_process GO:0015965 12133 2 42 1 3 1 1 false 0.6666666666666667 0.6666666666666667 0.33333333333333337 Ras_protein_signal_transduction GO:0007265 12133 365 42 1 547 1 1 false 0.667276051188237 0.667276051188237 2.1494674666292624E-150 homeostasis_of_number_of_cells GO:0048872 12133 166 42 1 990 6 1 false 0.6685476925042373 0.6685476925042373 1.128853988781411E-193 cellular_response_to_insulin_stimulus GO:0032869 12133 185 42 1 276 1 2 false 0.6702898550724703 0.6702898550724703 1.999097443178639E-75 regulation_of_response_to_stress GO:0080134 12133 674 42 3 3466 17 2 false 0.6706867747788551 0.6706867747788551 0.0 single_organism_reproductive_process GO:0044702 12133 539 42 2 8107 34 2 false 0.6707484365675813 0.6707484365675813 0.0 phosphoprotein_phosphatase_activity GO:0004721 12133 206 42 1 306 1 1 false 0.6732026143789835 0.6732026143789835 2.1851087098036358E-83 microtubule_cytoskeleton_organization GO:0000226 12133 259 42 1 831 3 2 false 0.6744082844812636 0.6744082844812636 4.0880234187670296E-223 regulation_of_neuronal_synaptic_plasticity GO:0048168 12133 35 42 1 82 2 1 false 0.6744956338452187 0.6744956338452187 5.621776882740478E-24 divalent_inorganic_cation_homeostasis GO:0072507 12133 223 42 1 330 1 1 false 0.6757575757575358 0.6757575757575358 1.0852171628360601E-89 steroid_metabolic_process GO:0008202 12133 182 42 1 5438 33 2 false 0.6759089994893156 0.6759089994893156 0.0 regulation_of_cellular_process GO:0050794 12133 6304 42 25 9757 40 2 false 0.6763513759488542 0.6763513759488542 0.0 positive_regulation_of_signaling GO:0023056 12133 817 42 3 4861 20 3 false 0.6778452027356692 0.6778452027356692 0.0 organ_development GO:0048513 12133 1929 42 9 3099 15 2 false 0.6781238787969397 0.6781238787969397 0.0 positive_regulation_of_mitochondrial_membrane_permeability GO:0035794 12133 38 42 2 46 2 1 false 0.6792270531400901 0.6792270531400901 3.832404138206993E-9 regulation_of_stress-activated_MAPK_cascade GO:0032872 12133 146 42 1 463 3 3 false 0.680012504935372 0.680012504935372 1.1657182873431035E-124 cyclic_nucleotide_biosynthetic_process GO:0009190 12133 151 42 1 348 2 2 false 0.6802477723675473 0.6802477723675473 8.533554981861938E-103 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 42 2 1804 7 2 false 0.6824469438535037 0.6824469438535037 0.0 myeloid_cell_differentiation GO:0030099 12133 237 42 1 2177 10 2 false 0.6849837778643912 0.6849837778643912 0.0 positive_regulation_of_cell_communication GO:0010647 12133 820 42 3 4819 20 3 false 0.68661096254291 0.68661096254291 0.0 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 42 17 6094 34 2 false 0.6868313177471469 0.6868313177471469 0.0 DNA_N-glycosylase_activity GO:0019104 12133 11 42 1 16 1 1 false 0.6874999999999987 0.6874999999999987 2.2893772893772823E-4 cell_periphery GO:0071944 12133 2667 42 10 9983 41 1 false 0.6888453296167979 0.6888453296167979 0.0 regulation_of_biological_process GO:0050789 12133 6622 42 25 10446 41 2 false 0.6895885312605506 0.6895885312605506 0.0 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 42 1 859 5 3 false 0.6900850030601515 0.6900850030601515 3.480270935062193E-190 response_to_insulin_stimulus GO:0032868 12133 216 42 1 313 1 1 false 0.6900958466453341 0.6900958466453341 1.4650294580642456E-83 cellular_ion_homeostasis GO:0006873 12133 478 42 2 575 2 2 false 0.6908226026360981 0.6908226026360981 1.064446434652655E-112 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 42 1 260 3 3 false 0.6915341101388329 0.6915341101388329 1.712440969539876E-70 regulation_of_MAP_kinase_activity GO:0043405 12133 268 42 2 533 4 3 false 0.692424210907808 0.692424210907808 1.0382438249699724E-159 developmental_growth GO:0048589 12133 223 42 1 2952 15 2 false 0.693068734193452 0.693068734193452 0.0 endoplasmic_reticulum_membrane GO:0005789 12133 487 42 1 3544 8 4 false 0.6938978681245338 0.6938978681245338 0.0 endoplasmic_reticulum_unfolded_protein_response GO:0030968 12133 82 42 1 118 1 3 false 0.6949152542372992 0.6949152542372992 3.7748187458517594E-31 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 42 9 181 9 1 false 0.695418000696852 0.695418000696852 8.905994863592909E-13 nitrogen_compound_transport GO:0071705 12133 428 42 2 2783 15 1 false 0.6963812485949854 0.6963812485949854 0.0 phosphatidylinositol_biosynthetic_process GO:0006661 12133 77 42 1 172 2 2 false 0.6963824289405605 0.6963824289405605 7.026012312452779E-51 membrane-bounded_vesicle GO:0031988 12133 762 42 4 834 4 1 false 0.6964013336847047 0.6964013336847047 6.820230733401612E-106 system_development GO:0048731 12133 2686 42 12 3304 15 2 false 0.696460803589019 0.696460803589019 0.0 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 42 4 2771 17 5 false 0.6981527892824639 0.6981527892824639 0.0 protein_kinase_binding GO:0019901 12133 341 42 3 384 3 1 false 0.699583620972628 0.699583620972628 5.20098898434574E-58 regulation_of_membrane_potential GO:0042391 12133 216 42 1 478 2 1 false 0.7000868398201406 0.7000868398201406 3.2092050959317294E-142 protein_phosphorylation GO:0006468 12133 1195 42 6 2577 14 2 false 0.7004542364508857 0.7004542364508857 0.0 chromatin_organization GO:0006325 12133 539 42 4 689 5 1 false 0.7008646561145457 0.7008646561145457 4.375882251809235E-156 organelle_inner_membrane GO:0019866 12133 264 42 1 9083 41 3 false 0.7024130229696502 0.7024130229696502 0.0 epithelial_cell_migration GO:0010631 12133 130 42 1 185 1 2 false 0.7027027027027377 0.7027027027027377 1.9916445787710798E-48 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 42 5 5183 23 2 false 0.7037145601412552 0.7037145601412552 0.0 regulation_of_JNK_cascade GO:0046328 12133 126 42 1 179 1 2 false 0.7039106145250991 0.7039106145250991 9.08597934181437E-47 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 42 3 803 4 1 false 0.7039167912703328 0.7039167912703328 1.0286714317927864E-202 transferase_activity,_transferring_acyl_groups_other_than_amino-acyl_groups GO:0016747 12133 131 42 2 156 2 1 false 0.7043010752687842 0.7043010752687842 1.7588456795479544E-29 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 42 1 650 4 2 false 0.7060649326602031 0.7060649326602031 6.010278185218431E-162 multicellular_organism_reproduction GO:0032504 12133 482 42 2 4643 23 2 false 0.7061748846057216 0.7061748846057216 0.0 cell-cell_signaling GO:0007267 12133 859 42 3 3969 16 2 false 0.7061800655972094 0.7061800655972094 0.0 biological_regulation GO:0065007 12133 6908 42 26 10446 41 1 false 0.7072870034997988 0.7072870034997988 0.0 endocytosis GO:0006897 12133 411 42 1 895 2 2 false 0.7078324772222511 0.7078324772222511 2.7872223899360555E-267 membrane_organization GO:0061024 12133 787 42 4 3745 22 1 false 0.7098239177619214 0.7098239177619214 0.0 adenylate_cyclase_activity GO:0004016 12133 103 42 1 145 1 3 false 0.710344827586197 0.710344827586197 1.7288474062512548E-37 proteasomal_protein_catabolic_process GO:0010498 12133 231 42 3 498 7 2 false 0.7114575535855512 0.7114575535855512 1.2543475178088858E-148 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 42 5 5032 34 4 false 0.7118184060436199 0.7118184060436199 0.0 cardiac_muscle_tissue_development GO:0048738 12133 129 42 1 482 4 2 false 0.7136325420958954 0.7136325420958954 6.1507462834425935E-121 pre-B_cell_differentiation GO:0002329 12133 5 42 1 7 1 1 false 0.7142857142857142 0.7142857142857142 0.047619047619047596 lipid_modification GO:0030258 12133 163 42 1 606 4 1 false 0.7154654478992628 0.7154654478992628 1.5937246255533045E-152 cell-type_specific_apoptotic_process GO:0097285 12133 270 42 2 1373 12 1 false 0.7167414932702227 0.7167414932702227 9.434604867208542E-295 response_to_radiation GO:0009314 12133 293 42 2 676 5 1 false 0.719174252664813 0.719174252664813 4.1946042901139895E-200 lymphocyte_activation GO:0046649 12133 403 42 2 475 2 1 false 0.7195469686876439 0.7195469686876439 3.3805466364584557E-87 cellular_divalent_inorganic_cation_homeostasis GO:0072503 12133 214 42 1 297 1 2 false 0.7205387205386926 0.7205387205386926 7.435405484383431E-76 epithelial_tube_morphogenesis GO:0060562 12133 245 42 1 340 1 2 false 0.7205882352939621 0.7205882352939621 6.979413529141176E-87 regulation_of_stress-activated_protein_kinase_signaling_cascade GO:0070302 12133 147 42 1 765 6 3 false 0.7233531301883886 0.7233531301883886 7.281108340064304E-162 spliceosomal_complex_assembly GO:0000245 12133 38 42 1 259 8 2 false 0.7242638143740101 0.7242638143740101 1.791986159229858E-46 morphogenesis_of_an_epithelium GO:0002009 12133 328 42 1 691 2 2 false 0.724394387466202 0.724394387466202 7.776670515222191E-207 protein_ubiquitination GO:0016567 12133 548 42 6 578 6 1 false 0.7252625707518345 0.7252625707518345 7.913703273197485E-51 neuron_part GO:0097458 12133 612 42 2 9983 41 1 false 0.7257770340168166 0.7257770340168166 0.0 cytosolic_calcium_ion_homeostasis GO:0051480 12133 149 42 1 205 1 1 false 0.726829268292646 0.726829268292646 9.962188539004893E-52 regulation_of_heart_contraction GO:0008016 12133 108 42 1 391 4 2 false 0.7271793723357463 0.7271793723357463 1.86290960303053E-99 negative_regulation_of_transport GO:0051051 12133 243 42 1 4618 24 3 false 0.7276468716729669 0.7276468716729669 0.0 vesicle_membrane GO:0012506 12133 312 42 1 9991 41 4 false 0.7283994661190136 0.7283994661190136 0.0 anatomical_structure_morphogenesis GO:0009653 12133 1664 42 7 3447 16 2 false 0.7289249138908348 0.7289249138908348 0.0 mRNA_transport GO:0051028 12133 106 42 2 124 2 1 false 0.7297403619197234 0.7297403619197234 4.872659948511352E-22 growth GO:0040007 12133 646 42 2 10446 41 1 false 0.7303035650673076 0.7303035650673076 0.0 organelle_assembly GO:0070925 12133 210 42 1 2677 16 2 false 0.7304318473142535 0.7304318473142535 7.5039E-319 epithelial_cell_proliferation GO:0050673 12133 225 42 1 1316 7 1 false 0.7317451545139868 0.7317451545139868 1.264012364925543E-260 positive_regulation_of_phosphorylation GO:0042327 12133 563 42 2 1487 6 3 false 0.7324912960167633 0.7324912960167633 0.0 protein_import GO:0017038 12133 225 42 1 2509 14 2 false 0.7325894376616711 0.7325894376616711 0.0 cellular_response_to_stimulus GO:0051716 12133 4236 42 17 7871 34 2 false 0.7329041638876844 0.7329041638876844 0.0 axon_guidance GO:0007411 12133 295 42 1 611 2 2 false 0.7329290869580484 0.7329290869580484 5.229199602535248E-183 response_to_external_stimulus GO:0009605 12133 1046 42 3 5200 18 1 false 0.7330796803197042 0.7330796803197042 0.0 regulation_of_cell_activation GO:0050865 12133 303 42 1 6351 27 2 false 0.7335748878927446 0.7335748878927446 0.0 poly-purine_tract_binding GO:0070717 12133 14 42 1 40 3 1 false 0.7368421052631625 0.7368421052631625 4.309057712047628E-11 secretory_granule GO:0030141 12133 202 42 1 712 4 1 false 0.7376352700755602 0.7376352700755602 1.1363731817938802E-183 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 42 3 5051 18 3 false 0.7377742498510075 0.7377742498510075 0.0 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 42 5 3780 26 4 false 0.7404280481735499 0.7404280481735499 0.0 interaction_with_host GO:0051701 12133 387 42 4 417 4 2 false 0.7409900906291358 0.7409900906291358 1.9217516081652173E-46 DNA-dependent_DNA_replication GO:0006261 12133 93 42 1 257 3 1 false 0.7418731403066932 0.7418731403066932 1.72483826119428E-72 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 42 1 417 2 4 false 0.7421370595833163 0.7421370595833163 8.022991700655629E-125 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 42 6 106 6 2 false 0.7429136491774406 0.7429136491774406 9.867686559172291E-9 calcium_ion_homeostasis GO:0055074 12133 213 42 1 286 1 2 false 0.7447552447552452 0.7447552447552452 5.1764989660558217E-70 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 42 1 803 4 1 false 0.7451062718951604 0.7451062718951604 7.141936114023743E-209 condensed_chromosome_kinetochore GO:0000777 12133 79 42 1 106 1 2 false 0.7452830188679459 0.7452830188679459 8.498251857674866E-26 lipid_binding GO:0008289 12133 571 42 2 8962 41 1 false 0.7457757991280786 0.7457757991280786 0.0 catalytic_activity GO:0003824 12133 4901 42 18 10478 42 2 false 0.7460362845060713 0.7460362845060713 0.0 nuclear-transcribed_mRNA_poly(A)_tail_shortening GO:0000289 12133 28 42 1 223 10 3 false 0.7463020647495185 0.7463020647495185 3.162563462571223E-36 regulation_of_adenylate_cyclase_activity GO:0045761 12133 103 42 1 138 1 4 false 0.7463768115942113 0.7463768115942113 1.4792034822830027E-33 cell_growth GO:0016049 12133 299 42 1 7559 34 2 false 0.7472297847936066 0.7472297847936066 0.0 N-acetyltransferase_activity GO:0008080 12133 68 42 1 91 1 2 false 0.747252747252751 0.747252747252751 4.74214851415134E-22 single-organism_carbohydrate_metabolic_process GO:0044723 12133 385 42 1 515 1 1 false 0.7475728155339276 0.7475728155339276 1.0653300741927565E-125 protein_oligomerization GO:0051259 12133 288 42 2 743 6 1 false 0.7480032981934184 0.7480032981934184 1.196705520432063E-214 cellular_calcium_ion_homeostasis GO:0006874 12133 205 42 1 274 1 3 false 0.7481751824817352 0.7481751824817352 1.2663672117972438E-66 mammary_gland_development GO:0030879 12133 125 42 1 251 2 1 false 0.7490039840637394 0.7490039840637394 5.503793662567663E-75 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 42 1 1631 10 2 false 0.7490293383221256 0.7490293383221256 3.3133814045702313E-271 endomembrane_system GO:0012505 12133 1211 42 4 9983 41 1 false 0.7498261795181614 0.7498261795181614 0.0 mRNA_processing GO:0006397 12133 374 42 7 763 16 2 false 0.7503515649191341 0.7503515649191341 8.270510506831645E-229 metal_ion_transport GO:0030001 12133 455 42 1 606 1 1 false 0.7508250825082763 0.7508250825082763 4.665536224038032E-147 cellular_homeostasis GO:0019725 12133 585 42 2 7566 34 2 false 0.7511556598370506 0.7511556598370506 0.0 regulation_of_cytokine_production GO:0001817 12133 323 42 1 1562 6 2 false 0.7515428342832455 0.7515428342832455 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 42 5 400 5 2 false 0.7525272191527608 0.7525272191527608 1.150456419433401E-36 pattern_specification_process GO:0007389 12133 326 42 1 4373 18 3 false 0.7527480751078208 0.7527480751078208 0.0 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 42 5 3453 25 4 false 0.7528195066503249 0.7528195066503249 0.0 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 42 1 2943 16 3 false 0.7534927008149841 0.7534927008149841 0.0 single_fertilization GO:0007338 12133 49 42 1 65 1 1 false 0.753846153846139 0.753846153846139 1.543100485620412E-15 regionalization GO:0003002 12133 246 42 1 326 1 1 false 0.754601226993791 0.754601226993791 2.501957085662731E-78 large_ribosomal_subunit GO:0015934 12133 73 42 3 132 6 1 false 0.7546156461233067 0.7546156461233067 5.5437540818743186E-39 regulation_of_protein_ubiquitination GO:0031396 12133 176 42 1 1344 10 2 false 0.7555255669493618 0.7555255669493618 8.0617715234352E-226 immune_response GO:0006955 12133 1006 42 3 5335 20 2 false 0.7569114958660796 0.7569114958660796 0.0 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 42 5 4429 29 3 false 0.7594305456370347 0.7594305456370347 0.0 central_nervous_system_development GO:0007417 12133 571 42 2 2686 12 2 false 0.7597683019620888 0.7597683019620888 0.0 substrate-specific_transmembrane_transporter_activity GO:0022891 12133 502 42 1 660 1 2 false 0.7606060606062449 0.7606060606062449 4.8010140095396714E-157 muscle_contraction GO:0006936 12133 220 42 2 252 2 1 false 0.7617150445834636 0.7617150445834636 2.9388717314840356E-41 regulation_of_cellular_catabolic_process GO:0031329 12133 494 42 2 5000 27 3 false 0.7620980603631287 0.7620980603631287 0.0 cellular_component_morphogenesis GO:0032989 12133 810 42 3 5068 24 4 false 0.7626073132377191 0.7626073132377191 0.0 regulation_of_cell_projection_organization GO:0031344 12133 227 42 1 1532 9 2 false 0.7648292177985091 0.7648292177985091 2.603761260472357E-278 transport GO:0006810 12133 2783 42 15 2833 15 1 false 0.7650842951795587 0.7650842951795587 1.147202604491021E-108 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 42 1 207 3 2 false 0.7656889291561159 0.7656889291561159 2.976076769798144E-59 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 42 1 269 3 2 false 0.7666340200753399 0.7666340200753399 3.613555574654199E-77 regulation_of_anatomical_structure_morphogenesis GO:0022603 12133 528 42 2 2074 10 2 false 0.7668169097304166 0.7668169097304166 0.0 tube_morphogenesis GO:0035239 12133 260 42 1 2815 15 3 false 0.7671731035640279 0.7671731035640279 0.0 JNK_cascade GO:0007254 12133 159 42 1 207 1 1 false 0.7681159420289673 0.7681159420289673 3.1556682987155503E-48 mRNA_export_from_nucleus GO:0006406 12133 60 42 1 116 2 2 false 0.7691154422788684 0.7691154422788684 1.7435958103584361E-34 endothelial_cell_migration GO:0043542 12133 100 42 1 130 1 1 false 0.7692307692307458 0.7692307692307458 3.8279880512589226E-30 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 42 5 4298 29 4 false 0.771914710758814 0.771914710758814 0.0 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 42 1 136 1 2 false 0.7720588235294237 0.7720588235294237 2.4301849830786213E-31 cellular_response_to_organic_nitrogen GO:0071417 12133 323 42 1 1478 6 4 false 0.7729041458285582 0.7729041458285582 0.0 cardiac_ventricle_development GO:0003231 12133 75 42 1 97 1 1 false 0.7731958762886568 0.7731958762886568 2.8989180079238147E-22 DNA_methylation_or_demethylation GO:0044728 12133 48 42 1 62 1 1 false 0.7741935483871082 0.7741935483871082 3.438909653668478E-14 establishment_of_protein_localization_to_mitochondrion GO:0072655 12133 66 42 2 211 8 2 false 0.7744420761209051 0.7744420761209051 1.9619733177914497E-56 histone_acetylation GO:0016573 12133 121 42 1 309 3 2 false 0.7761975540665006 0.7761975540665006 3.1224257129978892E-89 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 42 1 90 1 3 false 0.7777777777777884 0.7777777777777884 1.9615250672171495E-20 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 42 2 1350 6 4 false 0.7786424177823192 0.7786424177823192 0.0 cell_projection GO:0042995 12133 976 42 3 9983 41 1 false 0.7786508666142274 0.7786508666142274 0.0 positive_regulation_of_hydrolase_activity GO:0051345 12133 562 42 1 2891 7 3 false 0.7801698503054695 0.7801698503054695 0.0 interphase GO:0051325 12133 233 42 3 253 3 1 false 0.7802990934809596 0.7802990934809596 4.555981744751407E-30 regulation_of_mononuclear_cell_proliferation GO:0032944 12133 128 42 1 164 1 2 false 0.780487804878083 0.780487804878083 4.363818297439258E-37 muscle_organ_development GO:0007517 12133 308 42 1 1966 9 2 false 0.7849560931084063 0.7849560931084063 0.0 regulation_of_protein_transport GO:0051223 12133 261 42 1 1665 9 3 false 0.7853041231297415 0.7853041231297415 3.65102727546E-313 response_to_DNA_damage_stimulus GO:0006974 12133 570 42 3 1124 7 1 false 0.7856893367789908 0.7856893367789908 0.0 metal_ion_binding GO:0046872 12133 2699 42 11 2758 11 1 false 0.7879615763871749 0.7879615763871749 2.6200760259069314E-123 RNA_biosynthetic_process GO:0032774 12133 2751 42 20 4191 33 3 false 0.7887008497750885 0.7887008497750885 0.0 protein_folding GO:0006457 12133 183 42 1 3038 25 1 false 0.7897701872608754 0.7897701872608754 1.582632936584301E-299 actin_cytoskeleton GO:0015629 12133 327 42 1 1430 6 1 false 0.7900662290170618 0.7900662290170618 0.0 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 42 1 312 1 1 false 0.7916666666666485 0.7916666666666485 8.216510305576978E-69 cell_communication GO:0007154 12133 3962 42 16 7541 34 1 false 0.7921178104138593 0.7921178104138593 0.0 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 42 2 3702 16 3 false 0.7921723562595041 0.7921723562595041 0.0 locomotion GO:0040011 12133 1045 42 3 10446 41 1 false 0.7922081721938508 0.7922081721938508 0.0 purine-containing_compound_biosynthetic_process GO:0072522 12133 280 42 1 4251 23 6 false 0.7922348102692456 0.7922348102692456 0.0 regulation_of_mRNA_stability GO:0043488 12133 33 42 2 37 2 1 false 0.792792792792794 0.792792792792794 1.5141191611779804E-5 neuron_differentiation GO:0030182 12133 812 42 3 2154 10 2 false 0.7933007892887246 0.7933007892887246 0.0 cytokine_production GO:0001816 12133 362 42 1 4095 17 1 false 0.7933350685498347 0.7933350685498347 0.0 cellular_response_to_nitrogen_compound GO:1901699 12133 347 42 1 1721 7 2 false 0.7938900811394496 0.7938900811394496 0.0 condensed_chromosome GO:0000793 12133 160 42 1 592 5 1 false 0.7943746220060388 0.7943746220060388 2.5509694139314793E-149 nuclear_chromatin GO:0000790 12133 151 42 1 368 3 2 false 0.796128284854751 0.796128284854751 1.5117378626822706E-107 stress-activated_MAPK_cascade GO:0051403 12133 207 42 1 504 3 2 false 0.7962170064416874 0.7962170064416874 1.7060805667457382E-147 regulation_of_response_to_external_stimulus GO:0032101 12133 314 42 1 2524 12 2 false 0.7976904976983086 0.7976904976983086 0.0 positive_regulation_of_molecular_function GO:0044093 12133 1303 42 4 10257 42 2 false 0.798632637373857 0.798632637373857 0.0 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 42 1 971 18 2 false 0.7986771547654059 0.7986771547654059 1.7939571902377886E-121 intracellular_protein_kinase_cascade GO:0007243 12133 806 42 4 1813 11 1 false 0.7995208821794034 0.7995208821794034 0.0 spindle_assembly_checkpoint GO:0071173 12133 36 42 1 45 1 1 false 0.8000000000000007 0.8000000000000007 1.1284603934692157E-9 regulation_of_cAMP_biosynthetic_process GO:0030817 12133 124 42 1 155 1 4 false 0.8000000000000121 0.8000000000000121 2.5860077232155615E-33 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 42 1 361 4 1 false 0.8030227978829908 0.8030227978829908 4.560830022372086E-99 macromolecular_complex_assembly GO:0065003 12133 973 42 8 1603 15 2 false 0.8041172294542622 0.8041172294542622 0.0 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 42 17 4395 29 3 false 0.8054035828004871 0.8054035828004871 0.0 induction_of_programmed_cell_death GO:0012502 12133 157 42 2 368 6 1 false 0.807988268854671 0.807988268854671 2.1106051638808005E-108 cellular_cation_homeostasis GO:0030003 12133 289 42 1 513 2 2 false 0.8098196881091319 0.8098196881091319 6.525965777081911E-152 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 42 4 723 7 2 false 0.8103322297077764 0.8103322297077764 2.0953844092707462E-201 regulation_of_lymphocyte_activation GO:0051249 12133 245 42 1 434 2 2 false 0.8109215525592754 0.8109215525592754 2.1869753110099554E-128 induction_of_apoptosis GO:0006917 12133 156 42 2 363 6 2 false 0.8123029180755906 0.8123029180755906 4.583372865169243E-107 second-messenger-mediated_signaling GO:0019932 12133 257 42 1 1813 11 1 false 0.8148411536635637 0.8148411536635637 1.643E-320 cellular_protein_complex_disassembly GO:0043624 12133 149 42 6 154 6 1 false 0.8175954281708957 0.8175954281708957 1.4793035521715585E-9 response_to_stimulus GO:0050896 12133 5200 42 18 10446 41 1 false 0.8186485210056182 0.8186485210056182 0.0 phosphatidylinositol_3-kinase_cascade GO:0014065 12133 75 42 1 173 3 1 false 0.8206512382583309 0.8206512382583309 6.333263082873936E-51 angiogenesis GO:0001525 12133 300 42 1 2776 15 3 false 0.820951796163959 0.820951796163959 0.0 carboxylic_acid_metabolic_process GO:0019752 12133 614 42 2 7453 37 2 false 0.8211827904186553 0.8211827904186553 0.0 endoplasmic_reticulum_part GO:0044432 12133 593 42 2 7185 37 3 false 0.8220197712177397 0.8220197712177397 0.0 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 42 1 506 4 3 false 0.8224197439192596 0.8224197439192596 1.5079927652081954E-141 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 42 3 5778 22 3 false 0.8243600367613666 0.8243600367613666 0.0 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 42 4 3771 26 4 false 0.8248102862322777 0.8248102862322777 0.0 regulation_of_growth GO:0040008 12133 447 42 1 6651 25 2 false 0.8249323034164654 0.8249323034164654 0.0 nervous_system_development GO:0007399 12133 1371 42 5 2686 12 1 false 0.8262220489979906 0.8262220489979906 0.0 protein-DNA_complex_subunit_organization GO:0071824 12133 147 42 1 1256 14 1 false 0.8266260966944896 0.8266260966944896 3.54580927907897E-196 microtubule-based_process GO:0007017 12133 378 42 1 7541 34 1 false 0.8266458716234519 0.8266458716234519 0.0 generation_of_neurons GO:0048699 12133 883 42 3 940 3 1 false 0.8287220853101755 0.8287220853101755 7.799501535546468E-93 peptidyl-lysine_modification GO:0018205 12133 185 42 1 623 5 1 false 0.8294040749452893 0.8294040749452893 7.634244791194444E-164 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 42 4 4044 26 3 false 0.8300101500454877 0.8300101500454877 0.0 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 42 1 415 4 3 false 0.8300398939988625 0.8300398939988625 9.462933237946419E-117 negative_regulation_of_gene_expression GO:0010629 12133 817 42 5 3906 32 3 false 0.8301844161798503 0.8301844161798503 0.0 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 42 5 3631 32 4 false 0.8307555932623978 0.8307555932623978 0.0 substrate-specific_transporter_activity GO:0022892 12133 620 42 1 746 1 1 false 0.8310991957102674 0.8310991957102674 1.886990037563331E-146 hemopoiesis GO:0030097 12133 462 42 3 491 3 1 false 0.8327493480367946 0.8327493480367946 1.8682876304369947E-47 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 42 17 5532 34 4 false 0.8339736740635629 0.8339736740635629 0.0 activation_of_protein_kinase_activity GO:0032147 12133 247 42 1 417 2 1 false 0.8343824940050436 0.8343824940050436 9.475379918718814E-122 regulation_of_cell_growth GO:0001558 12133 243 42 1 1344 9 3 false 0.8348369507571258 0.8348369507571258 4.9010314548000585E-275 localization_of_cell GO:0051674 12133 785 42 3 3467 19 1 false 0.8392456423642483 0.8392456423642483 0.0 cell-cell_junction_organization GO:0045216 12133 152 42 1 181 1 1 false 0.8397790055249296 0.8397790055249296 3.1886200066761254E-34 response_to_decreased_oxygen_levels GO:0036293 12133 202 42 3 214 3 1 false 0.8403267426814965 0.8403267426814965 7.108512362452622E-20 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 42 1 2035 11 3 false 0.8404870154592023 0.8404870154592023 0.0 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 42 7 207 7 1 false 0.8405294364978887 0.8405294364978887 3.3148479610294504E-10 peptidyl-tyrosine_modification GO:0018212 12133 191 42 1 623 5 1 false 0.8408237886034496 0.8408237886034496 5.019013158282893E-166 cellular_metal_ion_homeostasis GO:0006875 12133 259 42 1 308 1 2 false 0.8409090909089498 0.8409090909089498 3.9623191237847456E-58 neurological_system_process GO:0050877 12133 894 42 3 1272 5 1 false 0.8410625404733736 0.8410625404733736 0.0 embryonic_limb_morphogenesis GO:0030326 12133 90 42 1 107 1 2 false 0.8411214953271113 0.8411214953271113 4.308534738445919E-20 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 42 6 645 7 1 false 0.8413579038495537 0.8413579038495537 7.3138241320053254E-93 transmembrane_transporter_activity GO:0022857 12133 544 42 1 904 2 2 false 0.8416781818721326 0.8416781818721326 4.222056161945909E-263 metal_ion_homeostasis GO:0055065 12133 278 42 1 330 1 1 false 0.8424242424241729 0.8424242424241729 6.131976736615521E-62 nucleic_acid_transport GO:0050657 12133 124 42 2 135 2 1 false 0.8431177446102683 0.8431177446102683 2.2345648964967124E-16 adherens_junction GO:0005912 12133 181 42 2 197 2 1 false 0.8437791360198781 0.8437791360198781 7.602023639007691E-24 N-acyltransferase_activity GO:0016410 12133 79 42 1 131 2 1 false 0.844274809160301 0.844274809160301 8.517686978921233E-38 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 42 2 768 4 1 false 0.8448419271963574 0.8448419271963574 1.6461815804374103E-220 cell_morphogenesis GO:0000902 12133 766 42 3 810 3 1 false 0.8455487699571632 0.8455487699571632 9.285456073507826E-74 androgen_receptor_signaling_pathway GO:0030521 12133 62 42 1 102 2 1 false 0.8485730926033468 0.8485730926033468 2.6706454874295595E-29 gamete_generation GO:0007276 12133 355 42 1 581 2 3 false 0.84910083684499 0.84910083684499 6.960007714092178E-168 telomere_maintenance_via_telomere_lengthening GO:0010833 12133 37 42 1 61 2 1 false 0.8491803278688709 0.8491803278688709 1.6824333127705717E-17 regulation_of_intracellular_protein_transport GO:0033157 12133 160 42 1 847 9 3 false 0.849572040168064 0.849572040168064 1.5386851760422239E-177 acetyltransferase_activity GO:0016407 12133 80 42 1 131 2 1 false 0.8502642395771909 0.8502642395771909 1.3104133813724972E-37 transmembrane_transport GO:0055085 12133 728 42 2 7606 34 2 false 0.8502832739344834 0.8502832739344834 0.0 regulation_of_cell_migration GO:0030334 12133 351 42 1 749 3 2 false 0.8504918913856537 0.8504918913856537 5.057884988188172E-224 protein_heterodimerization_activity GO:0046982 12133 317 42 2 779 7 1 false 0.8514074859038012 0.8514074859038012 8.49214053182804E-228 response_to_oxygen-containing_compound GO:1901700 12133 864 42 2 2369 8 1 false 0.8520548133151985 0.8520548133151985 0.0 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 42 1 1398 6 2 false 0.8523846493912179 0.8523846493912179 0.0 cellular_component_movement GO:0006928 12133 1012 42 3 7541 34 1 false 0.8534587774354757 0.8534587774354757 0.0 erythrocyte_homeostasis GO:0034101 12133 95 42 1 111 1 1 false 0.8558558558558544 0.8558558558558544 1.225965890705918E-19 cell_projection_organization GO:0030030 12133 744 42 2 7663 34 2 false 0.8560771289032875 0.8560771289032875 0.0 cytoskeleton_organization GO:0007010 12133 719 42 3 2031 12 1 false 0.8560801791418621 0.8560801791418621 0.0 cytoplasmic_vesicle_part GO:0044433 12133 366 42 1 7185 37 3 false 0.8562172674219612 0.8562172674219612 0.0 cation_homeostasis GO:0055080 12133 330 42 1 532 2 1 false 0.8562720360227958 0.8562720360227958 1.1320770482912473E-152 regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030802 12133 143 42 1 167 1 3 false 0.856287425149713 0.856287425149713 1.5904574919997758E-29 membrane GO:0016020 12133 4398 42 14 10701 41 1 false 0.8570615119677167 0.8570615119677167 0.0 acid-amino_acid_ligase_activity GO:0016881 12133 351 42 2 379 2 1 false 0.8575197889181455 0.8575197889181455 5.324332733169013E-43 anion_binding GO:0043168 12133 2280 42 7 4448 17 1 false 0.8591479708196654 0.8591479708196654 0.0 ubiquitin_binding GO:0043130 12133 61 42 1 71 1 1 false 0.8591549295774618 0.8591549295774618 2.1657301017057942E-12 response_to_wounding GO:0009611 12133 905 42 3 2540 12 1 false 0.8595943371844506 0.8595943371844506 0.0 in_utero_embryonic_development GO:0001701 12133 295 42 1 471 2 1 false 0.8608664227313849 0.8608664227313849 1.719393530200133E-134 positive_regulation_of_protein_modification_process GO:0031401 12133 708 42 3 2417 15 3 false 0.86148665590186 0.86148665590186 0.0 mitochondrial_envelope GO:0005740 12133 378 42 2 803 6 2 false 0.8616570991719563 0.8616570991719563 2.632819629334664E-240 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 42 5 1779 8 1 false 0.8618170344007468 0.8618170344007468 0.0 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 42 2 3447 16 2 false 0.8620629235325369 0.8620629235325369 0.0 developmental_process_involved_in_reproduction GO:0003006 12133 340 42 1 3959 22 2 false 0.86206386695713 0.86206386695713 0.0 regulation_of_nucleocytoplasmic_transport GO:0046822 12133 147 42 1 450 5 2 false 0.8630918634058243 0.8630918634058243 8.40005869125793E-123 organelle_membrane GO:0031090 12133 1619 42 5 9319 41 3 false 0.8634322685799272 0.8634322685799272 0.0 calcium_ion_binding GO:0005509 12133 447 42 1 2699 11 1 false 0.86408767192959 0.86408767192959 0.0 neurogenesis GO:0022008 12133 940 42 3 2425 11 2 false 0.8643338688987297 0.8643338688987297 0.0 actin_cytoskeleton_organization GO:0030036 12133 373 42 1 768 3 2 false 0.8644496902881873 0.8644496902881873 3.0657297438498186E-230 actin_filament-based_process GO:0030029 12133 431 42 1 7541 34 1 false 0.8654084077865807 0.8654084077865807 0.0 inorganic_cation_transmembrane_transporter_activity GO:0022890 12133 316 42 1 365 1 1 false 0.8657534246575868 0.8657534246575868 4.982755146780477E-62 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 42 1 3799 31 1 false 0.866521753867579 0.866521753867579 0.0 methyltransferase_activity GO:0008168 12133 126 42 1 199 2 2 false 0.8666057560529297 0.8666057560529297 2.689097193899432E-56 organic_acid_metabolic_process GO:0006082 12133 676 42 2 7326 37 2 false 0.8682114682743224 0.8682114682743224 0.0 enzyme_inhibitor_activity GO:0004857 12133 240 42 1 1075 8 2 false 0.868491029501825 0.868491029501825 4.258934911432728E-247 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 42 3 614 3 1 false 0.8691326427752593 0.8691326427752593 4.862693095923331E-49 programmed_cell_death GO:0012501 12133 1385 42 12 1525 14 1 false 0.8696363409158624 0.8696363409158624 2.142172117700311E-202 cell-cell_adhesion GO:0016337 12133 284 42 1 712 4 1 false 0.8701577612797144 0.8701577612797144 3.547957392630754E-207 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 42 8 2849 25 1 false 0.8709109003996428 0.8709109003996428 0.0 nuclear_outer_membrane-endoplasmic_reticulum_membrane_network GO:0042175 12133 499 42 1 10252 41 4 false 0.8712543346238351 0.8712543346238351 0.0 axonogenesis GO:0007409 12133 421 42 1 483 1 2 false 0.8716356107660534 0.8716356107660534 7.423880338325494E-80 receptor_binding GO:0005102 12133 918 42 3 6397 33 1 false 0.8720232452548775 0.8720232452548775 0.0 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 42 1 639 3 3 false 0.8738216846868159 0.8738216846868159 1.399157780258238E-191 RNA_polymerase_II_core_promoter_proximal_region_sequence-specific_DNA_binding_transcription_factor_activity_involved_in_positive_regulation_of_transcription GO:0001077 12133 59 42 1 92 2 2 false 0.8738652651695971 0.8738652651695971 9.681536258637415E-26 cell_projection_part GO:0044463 12133 491 42 1 9983 41 2 false 0.8740748183517676 0.8740748183517676 0.0 response_to_cytokine_stimulus GO:0034097 12133 461 42 1 1783 7 1 false 0.8773205057703672 0.8773205057703672 0.0 mitosis GO:0007067 12133 326 42 1 953 5 2 false 0.8773989064136815 0.8773989064136815 4.8424843971573165E-265 muscle_structure_development GO:0061061 12133 413 42 1 3152 15 2 false 0.8789684265218518 0.8789684265218518 0.0 response_to_peptide_hormone_stimulus GO:0043434 12133 313 42 1 619 3 2 false 0.8797927778303735 0.8797927778303735 1.4916788604957572E-185 regulation_of_small_GTPase_mediated_signal_transduction GO:0051056 12133 335 42 1 1759 10 2 false 0.8798241584382245 0.8798241584382245 0.0 chromatin GO:0000785 12133 287 42 2 512 5 1 false 0.8802415477540133 0.8802415477540133 9.050120143931621E-152 response_to_nitrogen_compound GO:1901698 12133 552 42 1 2369 8 1 false 0.8806683303937989 0.8806683303937989 0.0 protein_polyubiquitination GO:0000209 12133 163 42 1 548 6 1 false 0.8811478878838245 0.8811478878838245 3.681189236491621E-144 Golgi_apparatus_part GO:0044431 12133 406 42 1 7185 37 3 false 0.8844104804971976 0.8844104804971976 0.0 ion_binding GO:0043167 12133 4448 42 17 8962 41 1 false 0.8861368295446377 0.8861368295446377 0.0 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 42 1 4239 19 3 false 0.8866573831826252 0.8866573831826252 0.0 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 42 1 71 1 3 false 0.8873239436619828 0.8873239436619828 9.399268641403064E-11 cytoplasmic_vesicle_membrane GO:0030659 12133 302 42 1 719 4 3 false 0.8875414936949452 0.8875414936949452 1.2351303462379864E-211 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 42 1 5157 24 3 false 0.8876587983931111 0.8876587983931111 0.0 glucose_metabolic_process GO:0006006 12133 183 42 1 206 1 1 false 0.888349514563178 0.888349514563178 5.590923529140016E-31 glucocorticoid_receptor_signaling_pathway GO:0042921 12133 8 42 1 9 1 1 false 0.8888888888888886 0.8888888888888886 0.11111111111111104 cell-substrate_adherens_junction GO:0005924 12133 125 42 1 188 2 2 false 0.8888952099214251 0.8888952099214251 1.3846447149399673E-51 neuron_development GO:0048666 12133 654 42 2 1313 6 2 false 0.8893687889661104 0.8893687889661104 0.0 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 42 16 4544 33 3 false 0.8893879691211284 0.8893879691211284 0.0 regulation_of_protein_modification_process GO:0031399 12133 1001 42 5 2566 18 2 false 0.8916408134259431 0.8916408134259431 0.0 cellular_component_organization GO:0016043 12133 3745 42 22 3839 23 1 false 0.8922930495547975 0.8922930495547975 4.153510440731863E-191 positive_regulation_of_cell_proliferation GO:0008284 12133 558 42 2 3155 20 3 false 0.8927377249159913 0.8927377249159913 0.0 cellular_macromolecular_complex_assembly GO:0034622 12133 517 42 3 973 8 1 false 0.8937580691506504 0.8937580691506504 3.312522477266262E-291 homeostatic_process GO:0042592 12133 990 42 6 2082 17 1 false 0.8971587082849855 0.8971587082849855 0.0 organelle_fission GO:0048285 12133 351 42 1 2031 12 1 false 0.898086586855104 0.898086586855104 0.0 cytoskeletal_part GO:0044430 12133 1031 42 4 5573 34 2 false 0.8980872657293147 0.8980872657293147 0.0 endopeptidase_activity GO:0004175 12133 470 42 2 586 3 1 false 0.898451276776388 0.898451276776388 5.73935751356398E-126 response_to_metal_ion GO:0010038 12133 189 42 1 277 2 1 false 0.8998587348925946 0.8998587348925946 1.2236423246824455E-74 phosphatidylinositol_metabolic_process GO:0046488 12133 129 42 1 189 2 1 false 0.9003714961160685 0.9003714961160685 8.124346175289158E-51 apoptotic_process GO:0006915 12133 1373 42 12 1385 12 1 false 0.9004659074747391 0.9004659074747391 1.0085392941984968E-29 ncRNA_processing GO:0034470 12133 186 42 2 649 12 2 false 0.9009894966834394 0.9009894966834394 4.048832162241149E-168 'de_novo'_posttranslational_protein_folding GO:0051084 12133 46 42 1 51 1 1 false 0.9019607843137332 0.9019607843137332 4.2570219577192243E-7 response_to_light_stimulus GO:0009416 12133 201 42 1 293 2 1 false 0.9021459628782462 0.9021459628782462 1.3130246435910127E-78 protein_acetylation GO:0006473 12133 140 42 1 155 1 1 false 0.9032258064516349 0.9032258064516349 3.675799410957308E-21 embryonic_morphogenesis GO:0048598 12133 406 42 1 2812 15 3 false 0.9041796178256096 0.9041796178256096 0.0 nuclear_speck GO:0016607 12133 147 42 1 272 3 1 false 0.9042067626557826 0.9042067626557826 6.6218564870724965E-81 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 42 1 541 4 2 false 0.9062862987827687 0.9062862987827687 1.01164377942614E-160 phosphoric_ester_hydrolase_activity GO:0042578 12133 446 42 1 814 3 1 false 0.9080135224684638 0.9080135224684638 1.3758870371320904E-242 regulation_of_hormone_levels GO:0010817 12133 272 42 1 2082 17 1 false 0.9083619369761877 0.9083619369761877 0.0 repressing_transcription_factor_binding GO:0070491 12133 207 42 1 715 7 1 false 0.90970413899286 0.90970413899286 4.3536836236667346E-186 response_to_organic_nitrogen GO:0010243 12133 519 42 1 1787 7 3 false 0.9098703179217265 0.9098703179217265 0.0 protein_localization GO:0008104 12133 1434 42 11 1642 14 1 false 0.9100603385386954 0.9100603385386954 3.426309620265761E-270 small_conjugating_protein_ligase_activity GO:0019787 12133 335 42 2 351 2 1 false 0.9107855107856718 0.9107855107856718 5.577217121688537E-28 epithelium_development GO:0060429 12133 627 42 1 1132 3 1 false 0.9115083232271376 0.9115083232271376 0.0 microtubule_organizing_center GO:0005815 12133 413 42 1 1076 5 2 false 0.9116955066281125 0.9116955066281125 2.6476518998275E-310 actin_filament_organization GO:0007015 12133 195 42 1 1147 13 2 false 0.9125303093284733 0.9125303093284733 2.5334935844901407E-226 hydrolase_activity GO:0016787 12133 2556 42 7 4901 18 1 false 0.9142044015281098 0.9142044015281098 0.0 regulation_of_gene_expression GO:0010468 12133 2935 42 19 4361 33 2 false 0.9142145626758145 0.9142145626758145 0.0 internal_protein_amino_acid_acetylation GO:0006475 12133 128 42 1 140 1 1 false 0.914285714285699 0.914285714285699 1.3721041217101573E-17 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 42 1 442 3 3 false 0.9148704936520337 0.9148704936520337 4.945935388068452E-131 translation_initiation_factor_activity GO:0003743 12133 50 42 1 191 8 2 false 0.9164034502038457 0.9164034502038457 3.1223441687767467E-47 plasma_membrane_part GO:0044459 12133 1329 42 3 10213 41 3 false 0.9164931866284339 0.9164931866284339 0.0 regulation_of_transport GO:0051049 12133 942 42 3 3017 16 2 false 0.9178567275347196 0.9178567275347196 0.0 defense_response GO:0006952 12133 1018 42 3 2540 12 1 false 0.917892441747517 0.917892441747517 0.0 sexual_reproduction GO:0019953 12133 407 42 2 1345 12 1 false 0.9187868777204916 0.9187868777204916 0.0 T_cell_activation GO:0042110 12133 288 42 1 403 2 1 false 0.9190770712196987 0.9190770712196987 5.060432780788644E-104 small_GTPase_binding GO:0031267 12133 126 42 1 137 1 1 false 0.9197080291970834 0.9197080291970834 1.8889221296599312E-16 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 42 8 2805 8 1 false 0.9201262054482057 0.9201262054482057 1.0460685646312495E-69 glycosaminoglycan_binding GO:0005539 12133 127 42 1 138 1 1 false 0.920289855072456 0.920289855072456 1.738355872947893E-16 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 42 1 929 7 2 false 0.9204512112042013 0.9204512112042013 1.7613668775256747E-246 Golgi_apparatus GO:0005794 12133 828 42 2 8213 40 2 false 0.9223133684255397 0.9223133684255397 0.0 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 42 5 378 5 1 false 0.9227177891663332 0.9227177891663332 2.5686196448553377E-13 centrosome GO:0005813 12133 327 42 1 3226 24 2 false 0.9238272344365488 0.9238272344365488 0.0 centrosome_organization GO:0051297 12133 61 42 1 66 1 1 false 0.924242424242419 0.924242424242419 1.1189527318559458E-7 cation_transport GO:0006812 12133 606 42 1 833 2 1 false 0.9259771216182419 0.9259771216182419 4.047492354513465E-211 nuclear_division GO:0000280 12133 326 42 1 351 1 1 false 0.9287749287750802 0.9287749287750802 8.671827254018066E-39 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 42 35 7976 41 2 false 0.92950993520757 0.92950993520757 0.0 carbohydrate_metabolic_process GO:0005975 12133 515 42 1 7453 37 2 false 0.9297693090448722 0.9297693090448722 0.0 endoplasmic_reticulum GO:0005783 12133 854 42 2 8213 40 2 false 0.9306248249554283 0.9306248249554283 0.0 cell_cycle_checkpoint GO:0000075 12133 202 42 1 217 1 1 false 0.9308755760368301 0.9308755760368301 1.925703524045096E-23 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 42 14 3120 20 4 false 0.9316234429312458 0.9316234429312458 0.0 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 42 1 442 4 3 false 0.9337310150655743 0.9337310150655743 2.4953498472018727E-132 secretion_by_cell GO:0032940 12133 578 42 1 7547 34 3 false 0.9338115655419288 0.9338115655419288 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 42 17 3611 26 3 false 0.9350453597835928 0.9350453597835928 0.0 neuron_projection_morphogenesis GO:0048812 12133 475 42 1 637 2 2 false 0.935620982790638 0.935620982790638 3.7535814082411355E-156 membrane-bounded_organelle GO:0043227 12133 7284 42 35 7980 41 1 false 0.9381735709632244 0.9381735709632244 0.0 limb_morphogenesis GO:0035108 12133 107 42 1 114 1 2 false 0.9385964912280663 0.9385964912280663 2.4303191085943817E-11 cellular_protein_complex_assembly GO:0043623 12133 284 42 1 958 8 2 false 0.940711219234157 0.940711219234157 4.57678794545446E-252 protein_homodimerization_activity GO:0042803 12133 471 42 2 1035 8 2 false 0.9409851191654134 0.9409851191654134 7.159384282986134E-309 response_to_glucocorticoid_stimulus GO:0051384 12133 96 42 1 102 1 1 false 0.9411764705882397 0.9411764705882397 7.426393311971062E-10 double-stranded_DNA_binding GO:0003690 12133 109 42 1 179 3 1 false 0.941761558585837 0.941761558585837 1.5496409193142626E-51 purine_ribonucleotide_binding GO:0032555 12133 1641 42 5 1660 5 2 false 0.9440002696680627 0.9440002696680627 8.870449707822982E-45 internal_peptidyl-lysine_acetylation GO:0018393 12133 124 42 1 131 1 2 false 0.9465648854961779 0.9465648854961779 8.960493506706349E-12 ubiquitin-protein_ligase_activity GO:0004842 12133 321 42 2 558 6 2 false 0.9473668496799156 0.9473668496799156 1.7708856343357755E-164 response_to_unfolded_protein GO:0006986 12133 126 42 1 133 1 1 false 0.9473684210526476 0.9473684210526476 8.038720251232349E-12 membrane_invagination GO:0010324 12133 411 42 1 784 4 1 false 0.9491967151745032 0.9491967151745032 8.658368437912315E-235 hexose_metabolic_process GO:0019318 12133 206 42 1 217 1 1 false 0.9493087557602818 0.9493087557602818 1.0279992997812003E-18 virus-host_interaction GO:0019048 12133 355 42 4 588 10 2 false 0.9494515195180426 0.9494515195180426 1.0104535019427035E-170 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 42 2 2807 8 3 false 0.9497827400700418 0.9497827400700418 0.0 cytoskeletal_protein_binding GO:0008092 12133 556 42 1 6397 33 1 false 0.9506333205916645 0.9506333205916645 0.0 regulation_of_cell_cycle_process GO:0010564 12133 382 42 1 1096 7 2 false 0.9507122340570837 0.9507122340570837 7.137372224746455E-307 protein_modification_process GO:0036211 12133 2370 42 14 3518 26 2 false 0.9510069738942579 0.9510069738942579 0.0 signaling_receptor_activity GO:0038023 12133 633 42 2 1211 7 2 false 0.9515797950328307 0.9515797950328307 0.0 tissue_development GO:0009888 12133 1132 42 3 3099 15 1 false 0.9518397692126751 0.9518397692126751 0.0 Ras_GTPase_binding GO:0017016 12133 120 42 1 126 1 1 false 0.9523809523809658 0.9523809523809658 2.030392220357244E-10 protein_complex_assembly GO:0006461 12133 743 42 6 1214 14 3 false 0.9529369394056769 0.9529369394056769 0.0 protein_import_into_nucleus GO:0006606 12133 200 42 1 690 9 5 false 0.9550445959185055 0.9550445959185055 1.1794689955817937E-179 transporter_activity GO:0005215 12133 746 42 1 10383 42 2 false 0.9566286771169613 0.9566286771169613 0.0 multicellular_organismal_reproductive_process GO:0048609 12133 477 42 2 1275 11 2 false 0.9569183813670752 0.9569183813670752 0.0 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 42 1 4947 28 2 false 0.9571652891854175 0.9571652891854175 0.0 ion_transmembrane_transporter_activity GO:0015075 12133 469 42 1 589 2 2 false 0.9587678874605325 0.9587678874605325 1.1842155919657181E-128 organonitrogen_compound_biosynthetic_process GO:1901566 12133 548 42 1 5099 28 2 false 0.9589304925729596 0.9589304925729596 0.0 regulation_of_immune_system_process GO:0002682 12133 794 42 1 6789 26 2 false 0.960843224349893 0.960843224349893 0.0 activation_of_adenylate_cyclase_activity GO:0007190 12133 50 42 1 52 1 1 false 0.9615384615384723 0.9615384615384723 7.54147812971345E-4 calcium_ion_transport GO:0006816 12133 228 42 1 237 1 1 false 0.962025316455779 0.962025316455779 1.7939063205832563E-16 organophosphate_metabolic_process GO:0019637 12133 1549 42 4 7521 37 2 false 0.9627303352213397 0.9627303352213397 0.0 mononuclear_cell_proliferation GO:0032943 12133 161 42 1 167 1 1 false 0.9640718562873847 0.9640718562873847 3.634774947475864E-11 nucleocytoplasmic_transport GO:0006913 12133 327 42 3 331 3 1 false 0.9640751355092443 0.9640751355092443 2.036102168267257E-9 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 42 1 1079 6 3 false 0.9650636614902305 0.9650636614902305 5.98264E-319 striated_muscle_tissue_development GO:0014706 12133 285 42 1 295 1 1 false 0.9661016949152815 0.9661016949152815 8.482306621073292E-19 cell_projection_morphogenesis GO:0048858 12133 541 42 1 946 4 3 false 0.966691056673613 0.966691056673613 1.1683643564827775E-279 cell_part_morphogenesis GO:0032990 12133 551 42 1 810 3 1 false 0.9675654637983137 0.9675654637983137 1.1709501739830369E-219 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 42 5 672 14 1 false 0.9693137412280293 0.9693137412280293 6.935915883902889E-199 nuclear-transcribed_mRNA_catabolic_process,_deadenylation-dependent_decay GO:0000288 12133 55 42 1 174 9 1 false 0.9703717786421064 0.9703717786421064 1.101517519027427E-46 oxoacid_metabolic_process GO:0043436 12133 667 42 2 676 2 1 false 0.9735305719925577 0.9735305719925577 1.2985791548492531E-20 small_molecule_metabolic_process GO:0044281 12133 2423 42 5 2877 8 1 false 0.9747472730128239 0.9747472730128239 0.0 chordate_embryonic_development GO:0043009 12133 471 42 2 477 2 1 false 0.974974895618767 0.974974895618767 6.308586670641318E-14 purine_nucleoside_binding GO:0001883 12133 1631 42 5 1639 5 1 false 0.9758027023683856 0.9758027023683856 7.876250956196666E-22 focal_adhesion GO:0005925 12133 122 42 1 125 1 1 false 0.9759999999999686 0.9759999999999686 3.1471282454758027E-6 integral_to_membrane GO:0016021 12133 2318 42 1 2375 1 1 false 0.9760000000014666 0.9760000000014666 3.0839384482043954E-116 vesicle-mediated_transport GO:0016192 12133 895 42 2 2783 15 1 false 0.976208371491136 0.976208371491136 0.0 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 42 1 766 4 2 false 0.9764458681720793 0.9764458681720793 4.217322594612318E-222 organ_morphogenesis GO:0009887 12133 649 42 1 2908 15 3 false 0.977597055834819 0.977597055834819 0.0 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 42 5 3547 15 1 false 0.9777868458943839 0.9777868458943839 0.0 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 42 1 1218 1 2 false 0.9786535303778344 0.9786535303778344 3.12960829510125E-54 single-organism_metabolic_process GO:0044710 12133 2877 42 8 8027 37 1 false 0.9797477589310829 0.9797477589310829 0.0 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 42 2 199 2 1 false 0.9799502563321717 0.9799502563321717 5.075884472869322E-5 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 42 1 1813 11 1 false 0.9810034143427269 0.9810034143427269 0.0 purine_ribonucleoside_binding GO:0032550 12133 1629 42 5 1635 5 2 false 0.9817633940188508 0.9817633940188508 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 42 5 1639 5 1 false 0.9818076284736421 0.9818076284736421 3.7483303336303164E-17 ion_transport GO:0006811 12133 833 42 2 2323 14 1 false 0.9826403077506173 0.9826403077506173 0.0 protein_deacetylation GO:0006476 12133 57 42 1 58 1 1 false 0.982758620689673 0.982758620689673 0.017241379310345032 ribose_phosphate_metabolic_process GO:0019693 12133 1207 42 1 3007 8 3 false 0.9836169458319619 0.9836169458319619 0.0 viral_reproduction GO:0016032 12133 633 42 10 634 10 1 false 0.9842271293377558 0.9842271293377558 0.0015772870662463625 transcription_cofactor_activity GO:0003712 12133 456 42 3 482 4 2 false 0.9842794591643454 0.9842794591643454 1.3948726648763881E-43 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 42 5 2560 15 2 false 0.9850839436021728 0.9850839436021728 0.0 cytoskeleton GO:0005856 12133 1430 42 6 3226 24 1 false 0.9852897912929904 0.9852897912929904 0.0 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 42 2 504 5 1 false 0.9852912014754428 0.9852912014754428 6.011520399617331E-122 chemical_homeostasis GO:0048878 12133 677 42 2 990 6 1 false 0.9862898501374915 0.9862898501374915 1.9931274413677286E-267 cell_migration GO:0016477 12133 734 42 2 785 3 1 false 0.9880884523075354 0.9880884523075354 1.8763224028220524E-81 transcription,_DNA-dependent GO:0006351 12133 2643 42 15 4063 32 3 false 0.98923854142164 0.98923854142164 0.0 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 42 4 7461 37 2 false 0.9901287463107544 0.9901287463107544 0.0 extracellular_region GO:0005576 12133 1152 42 1 10701 41 1 false 0.990713563682547 0.990713563682547 0.0 purine_nucleotide_metabolic_process GO:0006163 12133 1208 42 1 1337 2 2 false 0.9907559600320303 0.9907559600320303 1.5771526523631757E-183 secretion GO:0046903 12133 661 42 1 2323 14 1 false 0.9909354237052037 0.9909354237052037 0.0 intrinsic_to_membrane GO:0031224 12133 2375 42 1 2995 3 1 false 0.9911627839229261 0.9911627839229261 0.0 protein_complex GO:0043234 12133 2976 42 19 3462 27 1 false 0.9912138448817964 0.9912138448817964 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 42 8 7256 37 1 false 0.991600519919603 0.991600519919603 0.0 protein_targeting_to_nucleus GO:0044744 12133 200 42 1 443 8 1 false 0.9922256996977943 0.9922256996977943 9.352491047681514E-132 ribonucleotide_metabolic_process GO:0009259 12133 1202 42 1 1318 2 2 false 0.9923148093732888 0.9923148093732888 7.680938106405399E-170 epithelium_migration GO:0090132 12133 130 42 1 131 1 1 false 0.9923664122137256 0.9923664122137256 0.007633587786259341 nucleoside_binding GO:0001882 12133 1639 42 5 4455 29 3 false 0.9941115439834548 0.9941115439834548 0.0 protein_localization_to_nucleus GO:0034504 12133 233 42 1 516 9 1 false 0.9957646384198807 0.9957646384198807 1.4955266190313754E-153 cellular_protein_modification_process GO:0006464 12133 2370 42 14 3038 25 2 false 0.9965355841828056 0.9965355841828056 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 42 2 1319 2 1 false 0.9969685500003617 0.9969685500003617 1.1504554077729292E-6 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 42 14 3220 25 4 false 0.998205158060542 0.998205158060542 0.0 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 42 2 5657 32 2 false 0.9982564517508583 0.9982564517508583 0.0 DNA_binding GO:0003677 12133 2091 42 12 2849 25 1 false 0.9983093389888706 0.9983093389888706 0.0 purine-containing_compound_metabolic_process GO:0072521 12133 1232 42 1 5323 32 5 false 0.9997865510837124 0.9997865510837124 0.0 membrane_part GO:0044425 12133 2995 42 3 10701 41 2 false 0.999803539194726 0.999803539194726 0.0 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 42 1 7451 37 1 false 0.9998590915927001 0.9998590915927001 0.0 purine_nucleotide_binding GO:0017076 12133 1650 42 5 1997 13 1 false 0.9999511976381341 0.9999511976381341 0.0 ribonucleotide_binding GO:0032553 12133 1651 42 5 1997 13 1 false 0.9999523622856362 0.9999523622856362 0.0 GO:0000000 12133 11221 42 42 0 0 0 true 1.0 1.0 1.0 aminoacyl-tRNA_ligase_activity GO:0004812 12133 39 42 2 39 2 1 true 1.0 1.0 1.0 blood_circulation GO:0008015 12133 307 42 2 307 2 1 true 1.0 1.0 1.0 cullin_deneddylation GO:0010388 12133 9 42 1 9 1 1 true 1.0 1.0 1.0 channel_activity GO:0015267 12133 304 42 1 304 1 1 true 1.0 1.0 1.0 diadenosine_tetraphosphate_biosynthetic_process GO:0015966 12133 2 42 1 2 1 2 true 1.0 1.0 1.0 ligase_activity,_forming_aminoacyl-tRNA_and_related_compounds GO:0016876 12133 39 42 2 39 2 1 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 42 3 147 3 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 42 1 87 1 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 42 8 1169 8 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 42 4 417 4 1 true 1.0 1.0 1.0 phosphatidylinositol-mediated_signaling GO:0048015 12133 173 42 3 173 3 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 42 2 124 2 2 true 1.0 1.0 1.0 limb_development GO:0060173 12133 114 42 1 114 1 1 true 1.0 1.0 1.0