ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min translational_initiation GO:0006413 12133 160 31 17 7667 30 2 false 1.0821451601570401E-21 1.0821451601570401E-21 0.0 ribosomal_subunit GO:0044391 12133 132 31 16 7199 30 4 false 7.55600348304802E-21 7.55600348304802E-21 2.5906239763169356E-285 viral_transcription GO:0019083 12133 145 31 17 2964 23 3 false 1.6310018277428594E-18 1.6310018277428594E-18 1.0927707330622845E-250 cytosolic_part GO:0044445 12133 178 31 16 5117 26 2 false 9.212883505454538E-18 9.212883505454538E-18 0.0 translational_elongation GO:0006414 12133 121 31 16 3388 26 2 false 1.0149809459489502E-17 1.0149809459489502E-17 5.332026529203484E-226 ribosome GO:0005840 12133 210 31 16 6755 30 3 false 4.268655350288487E-17 4.268655350288487E-17 0.0 multi-organism_cellular_process GO:0044764 12133 634 31 20 9702 31 2 false 6.482939672968271E-17 6.482939672968271E-17 0.0 RNA_catabolic_process GO:0006401 12133 203 31 16 4368 24 3 false 1.4026260577856495E-16 1.4026260577856495E-16 0.0 ribonucleoprotein_complex GO:0030529 12133 569 31 19 9264 31 2 false 5.017789921696401E-16 5.017789921696401E-16 0.0 cellular_process_involved_in_reproduction GO:0048610 12133 469 31 17 9699 31 2 false 4.609967285830958E-15 4.609967285830958E-15 0.0 translation GO:0006412 12133 457 31 19 5433 28 3 false 8.878741232333866E-15 8.878741232333866E-15 0.0 structural_molecule_activity GO:0005198 12133 526 31 17 10257 31 1 false 1.2388181941701656E-14 1.2388181941701656E-14 0.0 cellular_component_disassembly GO:0022411 12133 351 31 16 7663 30 2 false 2.1742175345475907E-14 2.1742175345475907E-14 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 31 20 6457 29 3 false 6.916465020345538E-14 6.916465020345538E-14 0.0 multi-organism_process GO:0051704 12133 1180 31 21 10446 31 1 false 1.5945566401785426E-13 1.5945566401785426E-13 0.0 protein_targeting_to_ER GO:0045047 12133 104 31 16 721 17 3 false 1.8471717146994961E-13 1.8471717146994961E-13 1.514347826459292E-128 reproductive_process GO:0022414 12133 1275 31 21 10446 31 2 false 7.452160844157071E-13 7.452160844157071E-13 0.0 macromolecule_catabolic_process GO:0009057 12133 820 31 20 6846 29 2 false 1.0387682832444181E-12 1.0387682832444181E-12 0.0 reproduction GO:0000003 12133 1345 31 21 10446 31 1 false 2.147910922850502E-12 2.147910922850502E-12 0.0 protein_targeting GO:0006605 12133 443 31 17 2378 18 2 false 4.542344319064996E-12 4.542344319064996E-12 0.0 protein_complex_disassembly GO:0043241 12133 154 31 16 1031 19 2 false 1.9791287040721775E-11 1.9791287040721775E-11 4.7545827865276796E-188 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 31 16 1239 18 2 false 3.1501728130382764E-11 3.1501728130382764E-11 4.427655683668096E-244 macromolecular_complex_disassembly GO:0032984 12133 199 31 16 1380 21 2 false 2.127358977543354E-10 2.127358977543354E-10 1.9082717261040364E-246 translational_termination GO:0006415 12133 92 31 16 513 19 2 false 2.2063232380198003E-10 2.2063232380198003E-10 3.4634519853301643E-104 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 31 16 516 17 1 false 2.512484765029421E-10 2.512484765029421E-10 8.917305549619806E-119 cytosolic_ribosome GO:0022626 12133 92 31 16 296 16 2 false 2.870079013128308E-9 2.870079013128308E-9 4.2784789004852985E-79 mRNA_metabolic_process GO:0016071 12133 573 31 17 3294 23 1 false 3.553235851431845E-9 3.553235851431845E-9 0.0 macromolecular_complex GO:0032991 12133 3462 31 25 10701 31 1 false 4.222895214094919E-8 4.222895214094919E-8 0.0 mRNA_catabolic_process GO:0006402 12133 181 31 16 592 17 2 false 4.487519645713196E-8 4.487519645713196E-8 1.4563864024176219E-157 viral_genome_expression GO:0019080 12133 153 31 17 557 20 2 false 7.401279018077148E-8 7.401279018077148E-8 1.6461772406083414E-141 intracellular_transport GO:0046907 12133 1148 31 18 2815 18 2 false 8.99123655794222E-8 8.99123655794222E-8 0.0 protein_targeting_to_membrane GO:0006612 12133 145 31 16 443 17 1 false 1.1767131734792354E-7 1.1767131734792354E-7 5.648405296311656E-121 macromolecular_complex_subunit_organization GO:0043933 12133 1256 31 21 3745 25 1 false 2.6881885323176427E-7 2.6881885323176427E-7 0.0 macromolecule_localization GO:0033036 12133 1642 31 20 3467 20 1 false 3.03234016547811E-7 3.03234016547811E-7 0.0 establishment_of_protein_localization GO:0045184 12133 1153 31 18 3010 19 2 false 3.534109065645008E-7 3.534109065645008E-7 0.0 structural_constituent_of_ribosome GO:0003735 12133 152 31 15 526 17 1 false 3.7357005647153887E-7 3.7357005647153887E-7 1.18011379183299E-136 catabolic_process GO:0009056 12133 2164 31 21 8027 29 1 false 4.2080344824787977E-7 4.2080344824787977E-7 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 31 21 7502 29 2 false 5.566395290518708E-7 5.566395290518708E-7 0.0 cellular_macromolecule_localization GO:0070727 12133 918 31 19 2206 20 2 false 6.365222850990878E-7 6.365222850990878E-7 0.0 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 31 25 10446 31 1 false 7.074220432839831E-7 7.074220432839831E-7 0.0 cellular_localization GO:0051641 12133 1845 31 20 7707 30 2 false 8.241016633706212E-7 8.241016633706212E-7 0.0 protein_metabolic_process GO:0019538 12133 3431 31 26 7395 29 2 false 1.2682336897650833E-6 1.2682336897650833E-6 0.0 viral_infectious_cycle GO:0019058 12133 213 31 18 557 20 1 false 1.582342833051729E-6 1.582342833051729E-6 3.455075709157513E-160 cytosol GO:0005829 12133 2226 31 23 5117 26 1 false 2.3787661313035208E-6 2.3787661313035208E-6 0.0 cellular_catabolic_process GO:0044248 12133 1972 31 20 7289 29 2 false 2.911019064191373E-6 2.911019064191373E-6 0.0 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 31 16 220 16 2 false 3.8035095661228895E-6 3.8035095661228895E-6 1.3850176335002185E-65 intracellular_protein_transport GO:0006886 12133 658 31 17 1672 19 3 false 7.897841489806129E-6 7.897841489806129E-6 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 31 16 5462 25 2 false 1.1964351792585708E-5 1.1964351792585708E-5 0.0 heterocycle_catabolic_process GO:0046700 12133 1243 31 16 5392 25 2 false 1.3795612278353373E-5 1.3795612278353373E-5 0.0 cellular_protein_metabolic_process GO:0044267 12133 3038 31 26 5899 29 2 false 1.4505432924704535E-5 1.4505432924704535E-5 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 31 16 5388 25 2 false 1.487969495707178E-5 1.487969495707178E-5 0.0 biosynthetic_process GO:0009058 12133 4179 31 26 8027 29 1 false 1.8838017326482654E-5 1.8838017326482654E-5 0.0 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 31 16 4878 24 5 false 1.9308458523969985E-5 1.9308458523969985E-5 0.0 organelle_part GO:0044422 12133 5401 31 27 10701 31 2 false 2.0635438069046087E-5 2.0635438069046087E-5 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 31 16 5528 26 2 false 2.561026918278472E-5 2.561026918278472E-5 0.0 macromolecule_biosynthetic_process GO:0009059 12133 3475 31 26 6537 29 2 false 3.025294804425384E-5 3.025294804425384E-5 0.0 organic_substance_transport GO:0071702 12133 1580 31 18 2783 18 1 false 3.600019701579183E-5 3.600019701579183E-5 0.0 RNA_binding GO:0003723 12133 763 31 14 2849 20 1 false 6.37694576093663E-5 6.37694576093663E-5 0.0 multi-organism_reproductive_process GO:0044703 12133 707 31 20 1275 21 1 false 6.72478049842445E-5 6.72478049842445E-5 0.0 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 31 26 6146 29 3 false 6.922661549567955E-5 6.922661549567955E-5 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 31 26 7470 29 2 false 7.608619172822598E-5 7.608619172822598E-5 0.0 cytokine_production GO:0001816 12133 362 31 5 4095 7 1 false 9.505617462502724E-5 9.505617462502724E-5 0.0 cellular_biosynthetic_process GO:0044249 12133 4077 31 26 7290 29 2 false 9.6459096238445E-5 9.6459096238445E-5 0.0 organelle GO:0043226 12133 7980 31 31 10701 31 1 false 1.1053126653138068E-4 1.1053126653138068E-4 0.0 ligase_activity GO:0016874 12133 504 31 7 4901 13 1 false 1.1524778774291651E-4 1.1524778774291651E-4 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 31 23 7980 31 1 false 1.3956852595852873E-4 1.3956852595852873E-4 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 31 23 7958 31 2 false 1.466988844425569E-4 1.466988844425569E-4 0.0 negative_regulation_of_ERBB_signaling_pathway GO:1901185 12133 39 31 3 705 3 3 false 1.5715667311408347E-4 1.5715667311408347E-4 4.9570646354646075E-65 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 31 29 7569 29 2 false 1.6842153733786757E-4 1.6842153733786757E-4 0.0 establishment_of_localization GO:0051234 12133 2833 31 18 10446 31 2 false 2.7572516839203447E-4 2.7572516839203447E-4 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 31 3 3208 11 2 false 2.9792068805733064E-4 2.9792068805733064E-4 7.591030632914061E-95 single-organism_transport GO:0044765 12133 2323 31 18 8134 30 2 false 3.143076297499189E-4 3.143076297499189E-4 0.0 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 31 23 4989 24 5 false 3.308227304169925E-4 3.308227304169925E-4 0.0 localization GO:0051179 12133 3467 31 20 10446 31 1 false 3.4455515627385814E-4 3.4455515627385814E-4 0.0 modulation_by_symbiont_of_host_cellular_process GO:0044068 12133 12 31 2 6306 16 2 false 3.925395143777834E-4 3.925395143777834E-4 1.2241582266777141E-37 heterocyclic_compound_binding GO:1901363 12133 4359 31 24 8962 30 1 false 4.189697890835898E-4 4.189697890835898E-4 0.0 protein_localization_to_organelle GO:0033365 12133 516 31 17 914 18 1 false 4.5695636235736656E-4 4.5695636235736656E-4 5.634955900168089E-271 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 31 3 1199 6 2 false 4.680423570379355E-4 4.680423570379355E-4 9.194442294553035E-70 organic_cyclic_compound_binding GO:0097159 12133 4407 31 24 8962 30 1 false 5.149148693178842E-4 5.149148693178842E-4 0.0 intracellular_organelle_part GO:0044446 12133 5320 31 27 9083 31 3 false 6.003203481805268E-4 6.003203481805268E-4 0.0 cytoplasmic_transport GO:0016482 12133 666 31 17 1148 18 1 false 7.219506141135771E-4 7.219506141135771E-4 0.0 gene_expression GO:0010467 12133 3708 31 26 6052 29 1 false 7.297464171051355E-4 7.297464171051355E-4 0.0 protein_transport GO:0015031 12133 1099 31 18 1627 18 2 false 8.188136657225988E-4 8.188136657225988E-4 0.0 establishment_of_localization_in_cell GO:0051649 12133 1633 31 18 2978 20 2 false 8.564621599927479E-4 8.564621599927479E-4 0.0 viral_reproductive_process GO:0022415 12133 557 31 20 783 20 2 false 9.959457750958116E-4 9.959457750958116E-4 1.4346997744229993E-203 cytoplasmic_part GO:0044444 12133 5117 31 26 9083 31 2 false 0.00113423491380959 0.00113423491380959 0.0 cellular_response_to_oxygen_levels GO:0071453 12133 85 31 3 1663 5 2 false 0.0011970916717897575 0.0011970916717897575 4.192529980934564E-145 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 31 16 174 16 1 false 0.0012147749679994263 0.0012147749679994263 2.5039480990851377E-47 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 31 10 200 16 3 false 0.0012179217870406272 0.0012179217870406272 7.491323649368413E-49 positive_regulation_of_signal_transduction GO:0009967 12133 782 31 7 3650 10 5 false 0.0013153765145482415 0.0013153765145482415 0.0 positive_regulation_of_signaling GO:0023056 12133 817 31 7 4861 12 3 false 0.0013399257275641175 0.0013399257275641175 0.0 positive_regulation_of_cell_communication GO:0010647 12133 820 31 7 4819 12 3 false 0.001445732266052584 0.001445732266052584 0.0 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 31 8 5778 14 3 false 0.001812412502458519 0.001812412502458519 0.0 regulation_of_cytokine_production GO:0001817 12133 323 31 5 1562 6 2 false 0.0018365685362777711 0.0018365685362777711 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 31 24 6846 29 2 false 0.0019317488139267121 0.0019317488139267121 0.0 intracellular_receptor_signaling_pathway GO:0030522 12133 217 31 4 3547 10 1 false 0.0021353277241842037 0.0021353277241842037 0.0 regulation_of_ERBB_signaling_pathway GO:1901184 12133 61 31 3 1663 8 2 false 0.0023073943448622763 0.0023073943448622763 5.186655572840897E-113 endosome_membrane GO:0010008 12133 248 31 4 1627 5 2 false 0.0023260615545245087 0.0023260615545245087 8.244139595488818E-301 single-organism_cellular_process GO:0044763 12133 7541 31 30 9888 31 2 false 0.0023681438690559098 0.0023681438690559098 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 31 29 7451 29 1 false 0.0023733422340506656 0.0023733422340506656 0.0 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 31 23 5597 27 2 false 0.002450942685613721 0.002450942685613721 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 31 23 5588 27 2 false 0.002566107843382308 0.002566107843382308 0.0 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 31 23 5686 27 2 false 0.0026387732145450047 0.0026387732145450047 0.0 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 31 4 2776 4 3 false 0.0028048017365793097 0.0028048017365793097 0.0 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 31 23 5629 27 2 false 0.0028213961082189055 0.0028213961082189055 0.0 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 31 16 145 16 1 false 0.0029040738052793606 0.0029040738052793606 1.7288474062512548E-37 single-organism_process GO:0044699 12133 8052 31 30 10446 31 1 false 0.003166537555508387 0.003166537555508387 0.0 endodermal-mesodermal_cell_signaling GO:0003133 12133 3 31 1 859 1 1 false 0.0034924330617009873 0.0034924330617009873 9.499264419714167E-9 cellular_metabolic_process GO:0044237 12133 7256 31 29 10007 31 2 false 0.0037026146258363085 0.0037026146258363085 0.0 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 31 3 1130 3 2 false 0.003985327842894698 0.003985327842894698 1.9819409219356823E-214 regulation_of_hematopoietic_stem_cell_proliferation GO:1902033 12133 1 31 1 1460 6 4 false 0.004109589041097461 0.004109589041097461 6.849315068495772E-4 regulation_of_hematopoietic_stem_cell_differentiation GO:1902036 12133 1 31 1 1459 6 4 false 0.004112405757371782 0.004112405757371782 6.85400959561964E-4 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 31 6 1975 6 1 false 0.004467463292033737 0.004467463292033737 0.0 cellular_response_to_hypoxia GO:0071456 12133 79 31 3 1210 6 3 false 0.004646305277229505 0.004646305277229505 3.484581288071841E-126 peptidyl-lysine_demalonylation GO:0036047 12133 1 31 1 185 1 2 false 0.005405405405405614 0.005405405405405614 0.005405405405405614 peptidyl-lysine_desuccinylation GO:0036049 12133 1 31 1 185 1 2 false 0.005405405405405614 0.005405405405405614 0.005405405405405614 protein_palmitoleylation GO:0045234 12133 1 31 1 177 1 2 false 0.005649717514124592 0.005649717514124592 0.005649717514124592 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 31 5 3842 12 3 false 0.006219372544478424 0.006219372544478424 0.0 NAD_binding GO:0051287 12133 43 31 2 2023 6 2 false 0.0062722756179691246 0.0062722756179691246 6.584917033488586E-90 endosome GO:0005768 12133 455 31 6 8213 31 2 false 0.006301564837107112 0.006301564837107112 0.0 virion_assembly GO:0019068 12133 11 31 2 2070 24 4 false 0.006649840608851373 0.006649840608851373 1.3710102562261885E-29 modulation_by_virus_of_host_process GO:0019054 12133 10 31 2 356 5 3 false 0.006804274947670941 0.006804274947670941 1.2608248051925915E-19 evasion_or_tolerance_of_defense_response_of_other_organism_involved_in_symbiotic_interaction GO:0051807 12133 1 31 1 1018 7 2 false 0.006876227897838474 0.006876227897838474 9.82318271119466E-4 immune_response-regulating_signaling_pathway GO:0002764 12133 310 31 4 3626 10 2 false 0.007265012632333966 0.007265012632333966 0.0 negative_regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042059 12133 39 31 3 197 3 3 false 0.007282710038330277 0.007282710038330277 3.777320475653026E-42 RNA_biosynthetic_process GO:0032774 12133 2751 31 23 4191 26 3 false 0.008253278966780188 0.008253278966780188 0.0 cellular_protein_localization GO:0034613 12133 914 31 18 1438 20 2 false 0.008328215761046694 0.008328215761046694 0.0 Notch_receptor_processing GO:0007220 12133 17 31 2 3038 26 1 false 0.00885317829473683 0.00885317829473683 2.325698863690895E-45 positive_regulation_of_NIK/NF-kappaB_cascade GO:1901224 12133 1 31 1 789 7 3 false 0.008871989860582368 0.008871989860582368 0.0012674271229399306 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 31 3 859 3 3 false 0.008928634106756954 0.008928634106756954 3.480270935062193E-190 negative_regulation_of_type_I_interferon_production GO:0032480 12133 32 31 3 148 3 3 false 0.00936916788188788 0.00936916788188788 3.492638478654734E-33 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 31 4 1384 7 2 false 0.009461630479255757 0.009461630479255757 1.3395090025049634E-243 endocytic_vesicle GO:0030139 12133 152 31 3 712 3 1 false 0.00957864000005613 0.00957864000005613 1.2528026489004738E-159 proteasomal_protein_catabolic_process GO:0010498 12133 231 31 6 498 6 2 false 0.009616077757712723 0.009616077757712723 1.2543475178088858E-148 regulation_of_Wnt_receptor_signaling_pathway_involved_in_heart_development GO:0003307 12133 5 31 1 1030 2 3 false 0.009689867625274226 0.009689867625274226 1.0452441066010245E-13 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 31 2 1977 8 3 false 0.009852874426445696 0.009852874426445696 8.49513097758148E-83 endodermal_cell_fate_specification GO:0001714 12133 7 31 1 2776 4 3 false 0.010053781797962128 0.010053781797962128 3.9974426345444845E-21 NLRP3_inflammasome_complex_assembly GO:0044546 12133 1 31 1 284 3 1 false 0.010563380281691362 0.010563380281691362 0.0035211267605635955 regulation_of_NLRP3_inflammasome_complex_assembly GO:1900225 12133 1 31 1 185 2 2 false 0.010810810810810634 0.010810810810810634 0.005405405405405614 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 31 4 5157 11 3 false 0.01131401555866475 0.01131401555866475 0.0 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 31 7 2370 11 1 false 0.012231267855482317 0.012231267855482317 0.0 HLH_domain_binding GO:0043398 12133 3 31 1 486 2 1 false 0.012320224004070186 0.012320224004070186 5.2592992299311226E-8 RING-like_zinc_finger_domain_binding GO:0071535 12133 3 31 1 486 2 1 false 0.012320224004070186 0.012320224004070186 5.2592992299311226E-8 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 31 2 2474 7 3 false 0.012724367001554845 0.012724367001554845 1.917782059478808E-128 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 31 3 2025 6 2 false 0.012756411376677806 0.012756411376677806 5.184659787643375E-271 membrane-enclosed_lumen GO:0031974 12133 3005 31 15 10701 31 1 false 0.012836902080322718 0.012836902080322718 0.0 cytoplasm GO:0005737 12133 6938 31 29 9083 31 1 false 0.01288317089685155 0.01288317089685155 0.0 negative_regulation_of_osteoblast_proliferation GO:0033689 12133 6 31 1 462 1 3 false 0.012987012987013687 0.012987012987013687 7.64957664126846E-14 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 31 2 243 3 2 false 0.013300361848079175 0.013300361848079175 1.7559807727942103E-26 regulation_of_osteoblast_proliferation GO:0033688 12133 14 31 1 1001 1 2 false 0.013986013986015233 0.013986013986015233 9.418706790424818E-32 induction_by_virus_of_host_cell-cell_fusion GO:0006948 12133 1 31 1 355 5 2 false 0.014084507042256035 0.014084507042256035 0.0028169014084507586 regulation_of_response_to_stimulus GO:0048583 12133 2074 31 10 7292 18 2 false 0.014176622254900061 0.014176622254900061 0.0 metabolic_process GO:0008152 12133 8027 31 29 10446 31 1 false 0.014836397971229265 0.014836397971229265 0.0 multi-organism_transport GO:0044766 12133 29 31 2 3441 23 2 false 0.015552040656447632 0.015552040656447632 2.716860412473803E-72 intracellular_organelle GO:0043229 12133 7958 31 31 9096 31 2 false 0.015753443067923204 0.015753443067923204 0.0 RNA_metabolic_process GO:0016070 12133 3294 31 23 5627 29 2 false 0.015766109849188026 0.015766109849188026 0.0 regulation_of_heart_induction_by_regulation_of_canonical_Wnt_receptor_signaling_pathway GO:0090081 12133 2 31 1 119 1 4 false 0.01680672268907591 0.01680672268907591 1.4242985329725256E-4 eukaryotic_translation_initiation_factor_2alpha_kinase_activity GO:0004694 12133 4 31 1 709 3 1 false 0.016853597304736817 0.016853597304736817 9.578723432074247E-11 protein_demalonylation GO:0036046 12133 1 31 1 58 1 1 false 0.017241379310345032 0.017241379310345032 0.017241379310345032 protein_desuccinylation GO:0036048 12133 1 31 1 58 1 1 false 0.017241379310345032 0.017241379310345032 0.017241379310345032 response_to_cytokine_stimulus GO:0034097 12133 461 31 4 1783 5 1 false 0.017581385603541267 0.017581385603541267 0.0 negative_regulation_of_gene_silencing_by_RNA GO:0060967 12133 1 31 1 55 1 3 false 0.018181818181817966 0.018181818181817966 0.018181818181817966 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 31 5 2935 14 1 false 0.0185840273783067 0.0185840273783067 0.0 regulation_of_hematopoietic_progenitor_cell_differentiation GO:1901532 12133 5 31 1 1597 6 4 false 0.018667815297184854 0.018667815297184854 1.1624617259156877E-14 positive_regulation_of_kinase_activity GO:0033674 12133 438 31 4 1181 4 3 false 0.01875600298706486 0.01875600298706486 0.0 regulation_of_kinetochore_assembly GO:0090234 12133 2 31 1 207 2 4 false 0.019276769382298758 0.019276769382298758 4.690211528539842E-5 endodermal_cell_differentiation GO:0035987 12133 15 31 1 3056 4 3 false 0.0194989301853292 0.0194989301853292 7.147345659783312E-41 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 31 4 1112 4 4 false 0.019597670536456294 0.019597670536456294 1.302733E-318 regulation_of_centromere_complex_assembly GO:0090230 12133 3 31 1 453 3 3 false 0.019779705130830022 0.019779705130830022 6.497377073847173E-8 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 31 4 3702 7 3 false 0.01996010766452965 0.01996010766452965 0.0 ubiquitin-protein_ligase_activity GO:0004842 12133 321 31 7 558 7 2 false 0.020272092062046058 0.020272092062046058 1.7708856343357755E-164 activation_of_immune_response GO:0002253 12133 341 31 4 1618 6 2 false 0.02028023146783341 0.02028023146783341 0.0 positive_regulation_of_phosphorylation GO:0042327 12133 563 31 4 1487 4 3 false 0.020412935633327325 0.020412935633327325 0.0 endocytic_vesicle_membrane GO:0030666 12133 97 31 3 352 3 2 false 0.020457320457324638 0.020457320457324638 2.1109282121886535E-89 positive_regulation_of_execution_phase_of_apoptosis GO:1900119 12133 6 31 1 2848 10 3 false 0.02090154163909879 0.02090154163909879 1.356380151997615E-18 endosomal_part GO:0044440 12133 257 31 4 7185 30 3 false 0.02108369253800245 0.02108369253800245 0.0 modification_by_symbiont_of_host_morphology_or_physiology GO:0044003 12133 20 31 2 404 5 2 false 0.02131541928475349 0.02131541928475349 2.92490996935113E-34 regulation_of_heart_induction GO:0090381 12133 5 31 1 1810 8 4 false 0.0219289848599793 0.0219289848599793 6.211404032103846E-15 cellular_macromolecular_complex_assembly GO:0034622 12133 517 31 6 973 6 1 false 0.02219875996083815 0.02219875996083815 3.312522477266262E-291 chromatin_silencing GO:0006342 12133 32 31 2 777 6 3 false 0.02223643428965976 0.02223643428965976 1.6134532448312596E-57 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 31 4 2035 8 3 false 0.022784937841071957 0.022784937841071957 0.0 protein_nitrosylation GO:0017014 12133 5 31 1 2370 11 1 false 0.023011574198101205 0.023011574198101205 1.6116589453687428E-15 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 31 6 742 6 2 false 0.023048120002052003 0.023048120002052003 9.121396596563632E-222 protein-malonyllysine_demalonylase_activity GO:0036054 12133 1 31 1 42 1 2 false 0.023809523809523944 0.023809523809523944 0.023809523809523944 protein-succinyllysine_desuccinylase_activity GO:0036055 12133 1 31 1 42 1 2 false 0.023809523809523944 0.023809523809523944 0.023809523809523944 osteoblast_proliferation GO:0033687 12133 16 31 1 1316 2 1 false 0.02417742438777983 0.02417742438777983 2.8332381652186863E-37 cell_projection_membrane GO:0031253 12133 147 31 2 1575 3 2 false 0.024375967492480492 0.024375967492480492 1.960515926193566E-211 negative_regulation_of_gene_expression,_epigenetic GO:0045814 12133 37 31 2 852 6 2 false 0.024664332166836715 0.024664332166836715 1.1400135698836375E-65 regulation_of_spindle_assembly GO:0090169 12133 3 31 1 240 2 4 false 0.024895397489536265 0.024895397489536265 4.3950634647156217E-7 AP-2_adaptor_complex GO:0030122 12133 8 31 1 1584 5 5 false 0.02503003843597826 0.02503003843597826 1.0355430852867986E-21 RNA-directed_RNA_polymerase_activity GO:0003968 12133 1 31 1 39 1 1 false 0.02564102564102553 0.02564102564102553 0.02564102564102553 NAD+_binding GO:0070403 12133 10 31 1 2303 6 2 false 0.025799507513255368 0.025799507513255368 8.817010194783993E-28 regulation_of_protein_stability GO:0031647 12133 99 31 2 2240 6 2 false 0.02582138808432029 0.02582138808432029 1.7785498552391114E-175 regulation_of_response_to_stress GO:0080134 12133 674 31 6 3466 13 2 false 0.026135128398273852 0.026135128398273852 0.0 RNA_phosphodiester_bond_hydrolysis GO:0090501 12133 4 31 1 3418 23 2 false 0.026657442180610277 0.026657442180610277 1.7615121152244582E-13 regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042058 12133 60 31 3 198 3 2 false 0.026856150859049993 0.026856150859049993 2.9049351003528108E-52 protein_polyubiquitination GO:0000209 12133 163 31 5 548 7 1 false 0.026925354773889514 0.026925354773889514 3.681189236491621E-144 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 31 4 1350 4 4 false 0.027371570248674346 0.027371570248674346 0.0 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 31 2 1056 4 3 false 0.02789899497435438 0.02789899497435438 4.764817151311381E-118 rRNA_3'-end_processing GO:0031125 12133 3 31 1 105 1 2 false 0.02857142857142789 0.02857142857142789 5.334471353888465E-6 negative_regulation_of_posttranscriptional_gene_silencing GO:0060149 12133 1 31 1 35 1 3 false 0.02857142857142864 0.02857142857142864 0.02857142857142864 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 31 3 86 3 2 false 0.02858119992183012 0.02858119992183012 6.233113581740502E-23 protein_K11-linked_ubiquitination GO:0070979 12133 26 31 3 163 5 1 false 0.029219831487858745 0.029219831487858745 1.0086078814809758E-30 ncRNA_3'-end_processing GO:0043628 12133 8 31 1 270 1 2 false 0.029629629629628444 0.029629629629628444 1.585153186118045E-15 clathrin_coat_of_coated_pit GO:0030132 12133 14 31 1 1370 3 3 false 0.030366667817244387 0.030366667817244387 1.135698186932346E-33 DNA_repair GO:0006281 12133 368 31 5 977 6 2 false 0.03080377829719192 0.03080377829719192 3.284245924949814E-280 T_cell_receptor_complex GO:0042101 12133 14 31 1 1342 3 2 false 0.030994080896309978 0.030994080896309978 1.5185236398759265E-33 negative_regulation_of_gene_silencing GO:0060969 12133 8 31 1 2538 10 3 false 0.031131972462372072 0.031131972462372072 2.3680102545031748E-23 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 31 2 2735 10 4 false 0.031153876092567315 0.031153876092567315 2.836340851870023E-153 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 31 3 1631 6 2 false 0.03127717593134499 0.03127717593134499 3.3133814045702313E-271 response_to_oxygen_levels GO:0070482 12133 214 31 3 676 3 1 false 0.03142091822302614 0.03142091822302614 1.6255941364061853E-182 regulation_of_chromosome_organization GO:0033044 12133 114 31 2 1070 3 2 false 0.03142438763046449 0.03142438763046449 5.856752364330647E-157 progesterone_receptor_binding GO:0033142 12133 2 31 1 62 1 1 false 0.032258064516129344 0.032258064516129344 5.288207297726192E-4 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 31 3 5033 12 3 false 0.032484070684791255 0.032484070684791255 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 31 24 8027 29 1 false 0.032628766278749666 0.032628766278749666 0.0 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 31 3 1663 9 2 false 0.03299568447839929 0.03299568447839929 7.181952736648417E-207 Wnt_receptor_signaling_pathway_involved_in_heart_development GO:0003306 12133 9 31 1 270 1 2 false 0.033333333333332014 0.033333333333332014 5.445182700405629E-17 immune_response GO:0006955 12133 1006 31 6 5335 14 2 false 0.033527398134000186 0.033527398134000186 0.0 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 31 2 953 4 3 false 0.033897798496316967 0.033897798496316967 1.5807807987211998E-114 coreceptor_activity GO:0015026 12133 22 31 1 633 1 1 false 0.034755134281206614 0.034755134281206614 3.8036191062904157E-41 intracellular_transport_of_viral_material GO:0075733 12133 23 31 2 355 5 2 false 0.035674744243478156 0.035674744243478156 1.1844258992565298E-36 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 31 6 381 6 2 false 0.036000327941680024 0.036000327941680024 4.820433761728018E-112 regulation_of_asymmetric_cell_division GO:0009786 12133 3 31 1 82 1 2 false 0.036585365853657646 0.036585365853657646 1.1291779584462383E-5 hematopoietic_stem_cell_differentiation GO:0060218 12133 8 31 1 644 3 2 false 0.036862637685546214 0.036862637685546214 1.4236055824919782E-18 fibrillar_center GO:0001650 12133 1 31 1 27 1 1 false 0.037037037037037035 0.037037037037037035 0.037037037037037035 signal_transduction_by_phosphorylation GO:0023014 12133 307 31 3 3947 10 2 false 0.0370742013037973 0.0370742013037973 0.0 regulation_of_execution_phase_of_apoptosis GO:1900117 12133 10 31 1 1061 4 2 false 0.03722255174759668 0.03722255174759668 2.0945178645052615E-24 hematopoietic_stem_cell_proliferation GO:0071425 12133 10 31 1 528 2 2 false 0.03755534471852874 0.03755534471852874 2.347802409190518E-21 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 31 24 7341 29 5 false 0.0376961297351633 0.0376961297351633 0.0 response_to_arsenic-containing_substance GO:0046685 12133 13 31 1 2369 7 1 false 0.03783335761682287 0.03783335761682287 8.694788313698481E-35 endocytic_recycling GO:0032456 12133 12 31 1 936 3 2 false 0.03801066465128626 0.03801066465128626 1.1370414551560961E-27 response_to_hypoxia GO:0001666 12133 200 31 3 2540 10 2 false 0.0381536866970381 0.0381536866970381 2.6634431659671552E-303 nucleic_acid_binding GO:0003676 12133 2849 31 20 4407 24 2 false 0.03873184163773796 0.03873184163773796 0.0 regulation_of_signal_transduction GO:0009966 12133 1603 31 8 3826 11 4 false 0.03903724193443395 0.03903724193443395 0.0 cleavage_involved_in_rRNA_processing GO:0000469 12133 4 31 1 102 1 2 false 0.039215686274509706 0.039215686274509706 2.353176494119972E-7 cell-cell_signaling_involved_in_cell_fate_commitment GO:0045168 12133 39 31 1 990 1 2 false 0.03939393939393697 0.03939393939393697 6.444259008282229E-71 ribosomal_protein_import_into_nucleus GO:0006610 12133 4 31 1 200 2 1 false 0.03969849246230797 0.03969849246230797 1.545954661787468E-8 negative_regulation_of_gene_silencing_by_miRNA GO:0060965 12133 1 31 1 25 1 4 false 0.04000000000000006 0.04000000000000006 0.04000000000000006 regulation_of_immune_system_process GO:0002682 12133 794 31 5 6789 17 2 false 0.04029414465180217 0.04029414465180217 0.0 beta-catenin_destruction_complex GO:0030877 12133 10 31 1 6481 27 2 false 0.04091572877982723 0.04091572877982723 2.794858090312749E-32 peptidyl-cysteine_S-nitrosylase_activity GO:0035605 12133 1 31 1 24 1 2 false 0.04166666666666653 0.04166666666666653 0.04166666666666653 evasion_or_tolerance_of_host_defenses_by_virus GO:0019049 12133 3 31 1 355 5 2 false 0.041777432733922586 0.041777432733922586 1.352523843304735E-7 Notch_signaling_pathway GO:0007219 12133 113 31 2 1975 6 1 false 0.041833544613526834 0.041833544613526834 2.33429872590278E-187 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 31 2 1813 5 1 false 0.04232506044786486 0.04232506044786486 4.219154160176784E-199 endoderm_development GO:0007492 12133 48 31 1 1132 1 1 false 0.0424028268551357 0.0424028268551357 8.876126303867437E-86 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 31 4 2780 4 2 false 0.042762081910899835 0.042762081910899835 0.0 cilium_membrane GO:0060170 12133 13 31 1 1781 6 3 false 0.043063551761928824 0.043063551761928824 3.586858251098541E-33 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 31 7 10311 31 3 false 0.043573214345485924 0.043573214345485924 0.0 cardiac_cell_fate_commitment GO:0060911 12133 11 31 1 252 1 2 false 0.043650793650789506 0.043650793650789506 1.913730632450975E-19 negative_regulation_of_metabolic_process GO:0009892 12133 1354 31 9 8327 30 3 false 0.04380560035161224 0.04380560035161224 0.0 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 31 2 6380 16 3 false 0.04393974009102448 0.04393974009102448 2.5067679665083333E-283 virus-infected_cell_apoptotic_process GO:0006926 12133 4 31 1 270 3 1 false 0.043950014487652726 0.043950014487652726 4.617949104611506E-9 asymmetric_cell_division GO:0008356 12133 10 31 1 438 2 1 false 0.04519189576084573 0.04519189576084573 1.5487001790918433E-20 gene_silencing GO:0016458 12133 87 31 2 7626 30 2 false 0.04553012870897904 0.04553012870897904 5.995921436880012E-206 regulation_of_phosphorylation GO:0042325 12133 845 31 4 1820 4 2 false 0.04628986651905065 0.04628986651905065 0.0 regulation_of_cell_fate_commitment GO:0010453 12133 22 31 1 938 2 2 false 0.04638266208215971 0.04638266208215971 5.88957448731009E-45 regulation_of_transcription_from_RNA_polymerase_II_promoter_involved_in_heart_development GO:1901213 12133 11 31 1 1376 6 2 false 0.047100606572507905 0.047100606572507905 1.2409561144903161E-27 regulation_of_gene_silencing GO:0060968 12133 19 31 1 6310 16 2 false 0.04715945281934153 0.04715945281934153 7.876216148484232E-56 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 31 9 7606 30 4 false 0.04771416228295017 0.04771416228295017 0.0 nucleosome_binding GO:0031491 12133 15 31 1 309 1 1 false 0.04854368932038486 0.04854368932038486 8.261563394863615E-26 cardiac_cell_fate_determination GO:0060913 12133 2 31 1 41 1 2 false 0.04878048780487835 0.04878048780487835 0.001219512195121968 regulation_of_cell_communication GO:0010646 12133 1796 31 8 6469 16 2 false 0.04883839775810912 0.04883839775810912 0.0 specification_of_organ_identity GO:0010092 12133 35 31 1 2782 4 3 false 0.049407921440110955 0.049407921440110955 3.589254890604921E-81 mRNA_transcription_from_RNA_polymerase_II_promoter GO:0042789 12133 10 31 1 1367 7 2 false 0.05020471404742211 0.05020471404742211 1.6459156458763548E-25 regulation_of_spindle_organization GO:0090224 12133 8 31 1 470 3 3 false 0.05030494011123726 0.05030494011123726 1.7978325867226666E-17 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 31 6 201 16 3 false 0.050403159779292536 0.050403159779292536 2.854176062301069E-41 regulation_of_chromatin_silencing GO:0031935 12133 12 31 1 2529 11 3 false 0.05107236713916721 0.05107236713916721 7.182938226109868E-33 regulation_of_multi-organism_process GO:0043900 12133 193 31 3 6817 30 2 false 0.051816219371186974 0.051816219371186974 0.0 positive_regulation_of_transferase_activity GO:0051347 12133 445 31 4 2275 8 3 false 0.052022149448980606 0.052022149448980606 0.0 BMP_signaling_pathway GO:0030509 12133 83 31 2 1276 6 2 false 0.05283968304778204 0.05283968304778204 9.874891335860256E-133 intracellular_part GO:0044424 12133 9083 31 31 9983 31 2 false 0.053211661177561084 0.053211661177561084 0.0 type_I_interferon_production GO:0032606 12133 71 31 3 362 5 1 false 0.05373302340837874 0.05373302340837874 2.8677775679244762E-77 regulation_of_transcription_involved_in_cell_fate_commitment GO:0060850 12133 11 31 1 1197 6 1 false 0.053996813362421583 0.053996813362421583 5.7827407119601044E-27 hematopoietic_progenitor_cell_differentiation GO:0002244 12133 30 31 1 2177 4 2 false 0.05402922703388543 0.05402922703388543 2.371815780130227E-68 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 31 3 207 3 2 false 0.05427764450713636 0.05427764450713636 2.976076769798144E-59 defense_response GO:0006952 12133 1018 31 7 2540 10 1 false 0.05499631257963539 0.05499631257963539 0.0 cell_surface_receptor_signaling_pathway_involved_in_heart_development GO:0061311 12133 20 31 1 2131 6 2 false 0.055069887550071674 0.055069887550071674 7.13339017282697E-49 peptidyl-cysteine_modification GO:0018198 12133 12 31 1 623 3 1 false 0.056768477401296244 0.056768477401296244 1.5587442311057763E-25 mRNA_transcription GO:0009299 12133 14 31 1 2643 11 1 false 0.05685297819485276 0.05685297819485276 1.1117998206344079E-37 cell_fate_determination GO:0001709 12133 33 31 1 2267 4 2 false 0.057004548628628915 0.057004548628628915 2.043725560941805E-74 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 31 24 7451 29 1 false 0.05718477138986727 0.05718477138986727 0.0 regulation_of_signaling GO:0023051 12133 1793 31 8 6715 17 2 false 0.057320838337456034 0.057320838337456034 0.0 regulation_of_kinase_activity GO:0043549 12133 654 31 4 1335 4 3 false 0.05732552547320177 0.05732552547320177 0.0 phosphatase_regulator_activity GO:0019208 12133 58 31 1 1010 1 2 false 0.05742574257426631 0.05742574257426631 7.00162504875011E-96 innate_immune_response GO:0045087 12133 626 31 6 1268 7 2 false 0.05796152672738568 0.05796152672738568 0.0 MHC_protein_binding GO:0042287 12133 27 31 1 918 2 1 false 0.057989608056976255 0.057989608056976255 1.6140071806590973E-52 oxidoreductase_activity,_acting_on_the_aldehyde_or_oxo_group_of_donors GO:0016903 12133 29 31 1 491 1 1 false 0.05906313645620593 0.05906313645620593 1.868287630437393E-47 apoptotic_signaling_pathway GO:0097190 12133 305 31 3 3954 12 2 false 0.05933304530133754 0.05933304530133754 0.0 response_to_defenses_of_other_organism_involved_in_symbiotic_interaction GO:0052173 12133 8 31 1 788 6 2 false 0.05957292819785683 0.05957292819785683 2.8105528686978E-19 response_to_host GO:0075136 12133 8 31 1 779 6 2 false 0.06024566288678615 0.06024566288678615 3.082345174293856E-19 heterocycle_metabolic_process GO:0046483 12133 4933 31 24 7256 29 1 false 0.06043033296815742 0.06043033296815742 0.0 primary_metabolic_process GO:0044238 12133 7288 31 29 8027 29 1 false 0.060445642683722337 0.060445642683722337 0.0 regulation_of_type_I_interferon_production GO:0032479 12133 67 31 3 325 5 2 false 0.06129146488586309 0.06129146488586309 2.788484219003069E-71 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 31 4 803 6 1 false 0.06130733176686068 0.06130733176686068 7.141936114023743E-209 molecular_function GO:0003674 12133 10257 31 31 11221 31 1 false 0.06151172539502195 0.06151172539502195 0.0 methylation-dependent_chromatin_silencing GO:0006346 12133 10 31 1 320 2 2 false 0.06161833855798284 0.06161833855798284 3.7149193025568033E-19 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 31 2 2180 8 2 false 0.061728829523017226 0.061728829523017226 1.341003616993524E-193 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 31 24 7256 29 1 false 0.06173062365299983 0.06173062365299983 0.0 nucleus GO:0005634 12133 4764 31 19 7259 23 1 false 0.06200593221642533 0.06200593221642533 0.0 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 31 2 1130 3 2 false 0.06290023596932136 0.06290023596932136 2.620015602340521E-209 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 31 3 750 3 3 false 0.06297950208128138 0.06297950208128138 3.090255244762607E-218 regulation_of_methylation-dependent_chromatin_silencing GO:0090308 12133 4 31 1 125 2 3 false 0.06322580645161026 0.06322580645161026 1.0318453263855228E-7 stem_cell_differentiation GO:0048863 12133 239 31 2 2154 4 1 false 0.06323118943497395 0.06323118943497395 0.0 NIK/NF-kappaB_cascade GO:0038061 12133 24 31 1 1828 5 2 false 0.0640124979865541 0.0640124979865541 3.725046499789671E-55 negative_regulation_of_response_to_DNA_damage_stimulus GO:2001021 12133 17 31 1 2816 11 4 false 0.06454891945623285 0.06454891945623285 8.478694604609857E-45 eukaryotic_translation_initiation_factor_3_complex GO:0005852 12133 16 31 1 6481 27 2 false 0.06468620504267297 0.06468620504267297 2.1998593675926732E-48 regulation_of_stem_cell_proliferation GO:0072091 12133 67 31 1 1017 1 2 false 0.06588003933137915 0.06588003933137915 1.0886769242827302E-106 translation_preinitiation_complex GO:0070993 12133 14 31 1 5307 26 2 false 0.06652564316478535 0.06652564316478535 6.309201044742604E-42 protein_kinase_A_binding GO:0051018 12133 21 31 1 6397 21 1 false 0.06682294117562289 0.06682294117562289 6.26776595449863E-61 regulation_of_protein_complex_assembly GO:0043254 12133 185 31 2 1610 4 3 false 0.06738670557640365 0.06738670557640365 1.34790682725651E-248 mitochondrial_intermembrane_space GO:0005758 12133 38 31 1 562 1 3 false 0.06761565836298093 0.06761565836298093 6.085523831675301E-60 phosphorylation GO:0016310 12133 1421 31 4 2776 4 1 false 0.06851762062747499 0.06851762062747499 0.0 stress-activated_MAPK_cascade GO:0051403 12133 207 31 3 504 3 2 false 0.06868931544483572 0.06868931544483572 1.7060805667457382E-147 negative_regulation_of_cytokine_production GO:0001818 12133 114 31 3 529 5 3 false 0.06959095738547397 0.06959095738547397 4.407958658606205E-119 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 31 6 2771 12 5 false 0.06962393072487083 0.06962393072487083 0.0 endosomal_transport GO:0016197 12133 133 31 3 2454 18 2 false 0.06993660761181657 0.06993660761181657 7.966947585336105E-224 modification_of_morphology_or_physiology_of_other_organism GO:0035821 12133 54 31 2 2831 23 2 false 0.07000201623995118 0.07000201623995118 1.511771633347702E-115 regulation_of_viral_reproduction GO:0050792 12133 101 31 2 6451 28 3 false 0.07050600941199517 0.07050600941199517 3.49743359338843E-225 vesicle_membrane GO:0012506 12133 312 31 3 9991 31 4 false 0.07128471457421082 0.07128471457421082 0.0 intracellular GO:0005622 12133 9171 31 31 9983 31 1 false 0.07178428704093864 0.07178428704093864 0.0 kinetochore_assembly GO:0051382 12133 9 31 1 487 4 4 false 0.07211424535318102 0.07211424535318102 2.5368495161977886E-19 DNA-directed_RNA_polymerase_II,_core_complex GO:0005665 12133 15 31 1 809 4 3 false 0.0722586881995281 0.0722586881995281 3.580788070603621E-32 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 31 3 856 4 3 false 0.07236948579893135 0.07236948579893135 2.175375701359491E-221 cytoplasmic_vesicle_membrane GO:0030659 12133 302 31 3 719 3 3 false 0.07367534920336355 0.07367534920336355 1.2351303462379864E-211 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 31 2 278 2 3 false 0.07402020621770027 0.07402020621770027 2.8121052478162137E-70 response_to_stress GO:0006950 12133 2540 31 10 5200 14 1 false 0.07620494366561886 0.07620494366561886 0.0 transferase_activity,_transferring_nitrogenous_groups GO:0016769 12133 20 31 1 1779 7 1 false 0.07621521134644912 0.07621521134644912 2.686330211236786E-47 blastocyst_development GO:0001824 12133 62 31 1 3152 4 3 false 0.07642433256478443 0.07642433256478443 7.043878358987507E-132 endodermal-mesodermal_cell_signaling_involved_in_heart_induction GO:0003134 12133 3 31 1 39 1 3 false 0.07692307692307658 0.07692307692307658 1.0942116205274074E-4 7-methylguanosine_mRNA_capping GO:0006370 12133 29 31 1 376 1 2 false 0.07712765957446956 0.07712765957446956 5.589278039185299E-44 positive_regulation_of_SMAD_protein_import_into_nucleus GO:0060391 12133 9 31 1 116 1 4 false 0.07758620689655255 0.07758620689655255 1.3117164604108179E-13 protein_K48-linked_ubiquitination GO:0070936 12133 37 31 3 163 5 1 false 0.07760692858417274 0.07760692858417274 1.6289154422281443E-37 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 31 2 3297 10 3 false 0.07799948427522659 0.07799948427522659 4.623981712175632E-272 rough_endoplasmic_reticulum GO:0005791 12133 34 31 1 854 2 1 false 0.07808506140341588 0.07808506140341588 1.2294025878223725E-61 regulation_of_ligase_activity GO:0051340 12133 98 31 2 2061 10 2 false 0.07852462050068407 0.07852462050068407 1.6310105681359867E-170 regulation_of_protein_kinase_activity GO:0045859 12133 621 31 4 1169 4 3 false 0.07927489096661264 0.07927489096661264 0.0 PML_body GO:0016605 12133 77 31 2 272 2 1 false 0.07939005860646028 0.07939005860646028 7.662735942565743E-70 organ_formation GO:0048645 12133 57 31 1 2776 4 3 false 0.07967909212181783 0.07967909212181783 3.8391380569752305E-120 synaptonemal_complex GO:0000795 12133 21 31 1 263 1 2 false 0.07984790874523809 0.07984790874523809 1.759650819297894E-31 positive_regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033145 12133 9 31 1 856 8 3 false 0.08140236098353648 0.08140236098353648 1.5339974177634096E-21 regulation_of_NIK/NF-kappaB_cascade GO:1901222 12133 17 31 1 1605 8 2 false 0.08183163035645301 0.08183163035645301 1.2442844653745033E-40 negative_regulation_of_ligase_activity GO:0051352 12133 71 31 2 1003 7 3 false 0.08229531999617463 0.08229531999617463 8.698138776450475E-111 binding GO:0005488 12133 8962 31 30 10257 31 1 false 0.08317644226994689 0.08317644226994689 0.0 regulation_of_heart_morphogenesis GO:2000826 12133 21 31 1 252 1 2 false 0.08333333333332552 0.08333333333332552 4.4779360311280245E-31 negative_regulation_of_DNA_repair GO:0045738 12133 7 31 1 407 5 4 false 0.08348458354514686 0.08348458354514686 2.8694471713419923E-15 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 31 24 7275 29 2 false 0.08777524044320002 0.08777524044320002 0.0 regulation_of_protein_phosphorylation GO:0001932 12133 787 31 4 1444 4 3 false 0.08792659036055317 0.08792659036055317 0.0 movement_in_environment_of_other_organism_involved_in_symbiotic_interaction GO:0052192 12133 21 31 1 1376 6 2 false 0.08830075092031327 0.08830075092031327 7.31086617582885E-47 regulation_of_cell_cycle_arrest GO:0071156 12133 89 31 2 481 3 2 false 0.08944461564503181 0.08944461564503181 1.91357850692127E-99 modification_of_morphology_or_physiology_of_other_organism_involved_in_symbiotic_interaction GO:0051817 12133 45 31 2 424 5 2 false 0.08953890183241332 0.08953890183241332 7.904014725959392E-62 cellular_response_to_stress GO:0033554 12133 1124 31 6 4743 14 2 false 0.08981687763836581 0.08981687763836581 0.0 intracellular_mRNA_localization GO:0008298 12133 5 31 1 1020 19 2 false 0.08990134893136566 0.08990134893136566 1.0976008922561835E-13 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 31 4 5830 15 3 false 0.09067448847058553 0.09067448847058553 0.0 glyceraldehyde-3-phosphate_dehydrogenase_(NAD+)_(phosphorylating)_activity GO:0004365 12133 2 31 1 22 1 1 false 0.09090909090909058 0.09090909090909058 0.004329004329004323 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 31 7 5447 25 3 false 0.09177081048458151 0.09177081048458151 0.0 positive_regulation_of_immune_system_process GO:0002684 12133 540 31 4 3595 12 3 false 0.09224386138495655 0.09224386138495655 0.0 cellular_process GO:0009987 12133 9675 31 31 10446 31 1 false 0.092509384158238 0.092509384158238 0.0 protein_C-terminus_binding GO:0008022 12133 157 31 2 6397 21 1 false 0.09275785658984576 0.09275785658984576 2.34014E-319 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds GO:0016810 12133 82 31 1 2556 3 1 false 0.09322480547204352 0.09322480547204352 6.720612726716271E-157 receptor_signaling_protein_activity GO:0005057 12133 339 31 3 1070 4 1 false 0.09657545088108514 0.09657545088108514 2.5248591221043436E-289 NADP_binding GO:0050661 12133 34 31 1 2023 6 2 false 0.09681179881570369 0.09681179881570369 1.5396057835546512E-74 microtubule_cytoskeleton_organization GO:0000226 12133 259 31 2 831 2 2 false 0.09688138836934784 0.09688138836934784 4.0880234187670296E-223 regulation_of_gene_silencing_by_RNA GO:0060966 12133 6 31 1 61 1 2 false 0.09836065573770608 0.09836065573770608 1.800978478811498E-8 heart_formation GO:0060914 12133 19 31 1 193 1 2 false 0.0984455958549198 0.0984455958549198 1.1408138520654599E-26 BMP_signaling_pathway_involved_in_heart_development GO:0061312 12133 5 31 1 98 2 3 false 0.09993688196928 0.09993688196928 1.472518447122031E-8 formation_of_primary_germ_layer GO:0001704 12133 74 31 1 2776 4 3 false 0.10249308774663271 0.10249308774663271 1.3578470482055665E-147 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 31 5 5051 13 3 false 0.10328788284813356 0.10328788284813356 0.0 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 31 2 260 2 3 false 0.10353430353430498 0.10353430353430498 1.712440969539876E-70 RNA_capping GO:0036260 12133 32 31 1 601 2 1 false 0.10373821408763463 0.10373821408763463 7.261717621132174E-54 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 31 2 859 3 3 false 0.10388739442771636 0.10388739442771636 4.662302019201105E-186 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 31 2 695 5 3 false 0.10392391312398955 0.10392391312398955 3.5521820546065696E-107 clathrin_coat_assembly GO:0048268 12133 11 31 1 305 3 2 false 0.10467285727709638 0.10467285727709638 2.2546926264184052E-20 cell_fate_specification GO:0001708 12133 62 31 1 2267 4 2 false 0.10505583407694809 0.10505583407694809 6.690929414026208E-123 cellular_protein_catabolic_process GO:0044257 12133 409 31 6 3174 26 3 false 0.10790176442186694 0.10790176442186694 0.0 biological_process GO:0008150 12133 10446 31 31 11221 31 1 false 0.10842626168848005 0.10842626168848005 0.0 regulation_of_transferase_activity GO:0051338 12133 667 31 4 2708 8 2 false 0.10844796325821897 0.10844796325821897 0.0 viral_assembly,_maturation,_egress,_and_release GO:0019067 12133 16 31 2 557 20 2 false 0.10875922200033208 0.10875922200033208 3.0295698614548545E-31 AP-type_membrane_coat_adaptor_complex GO:0030119 12133 32 31 1 7525 27 4 false 0.10886716049932874 0.10886716049932874 2.515530338610607E-89 organ_induction GO:0001759 12133 24 31 1 844 4 5 false 0.10916964782461135 0.10916964782461135 5.056432293707103E-47 regulation_of_gene_expression,_epigenetic GO:0040029 12133 120 31 2 2935 14 1 false 0.10954491902032079 0.10954491902032079 6.075348180017095E-217 NF-kappaB_binding GO:0051059 12133 21 31 1 715 4 1 false 0.11263341684968581 0.11263341684968581 7.883315092172008E-41 DNA-dependent_transcription,_initiation GO:0006352 12133 225 31 4 2751 23 2 false 0.11292302444627596 0.11292302444627596 0.0 positive_regulation_of_ligase_activity GO:0051351 12133 84 31 2 1424 10 3 false 0.11373097844722022 0.11373097844722022 5.130084211911676E-138 coated_membrane GO:0048475 12133 66 31 1 4398 8 1 false 0.11402062923121394 0.11402062923121394 3.1181974111959693E-148 organic_substance_metabolic_process GO:0071704 12133 7451 31 29 8027 29 1 false 0.11494111851622556 0.11494111851622556 0.0 response_to_DNA_damage_stimulus GO:0006974 12133 570 31 5 1124 6 1 false 0.11555273915385783 0.11555273915385783 0.0 cell_part GO:0044464 12133 9983 31 31 10701 31 2 false 0.11576517687873572 0.11576517687873572 0.0 ERBB_signaling_pathway GO:0038127 12133 199 31 3 586 4 1 false 0.11598346775781913 0.11598346775781913 2.435227003721618E-162 cell GO:0005623 12133 9984 31 31 10701 31 1 false 0.11612574359014964 0.11612574359014964 0.0 positive_regulation_of_peptidase_activity GO:0010952 12133 121 31 1 1041 1 3 false 0.11623439000961067 0.11623439000961067 8.90382030646545E-162 response_to_interferon-alpha GO:0035455 12133 14 31 1 461 4 1 false 0.11641478072498923 0.11641478072498923 5.434668916459107E-27 protein_ADP-ribosylation GO:0006471 12133 16 31 1 137 1 1 false 0.11678832116788625 0.11678832116788625 3.378397483752711E-21 maturation_of_5.8S_rRNA GO:0000460 12133 12 31 1 102 1 1 false 0.11764705882352931 0.11764705882352931 7.4019739755232135E-16 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 31 3 417 3 4 false 0.11792410371980254 0.11792410371980254 8.022991700655629E-125 regulation_of_SMAD_protein_import_into_nucleus GO:0060390 12133 10 31 1 244 3 3 false 0.11844726449790495 0.11844726449790495 5.8481730272741835E-18 regulation_of_organelle_assembly GO:1902115 12133 25 31 1 807 4 3 false 0.11848574099679855 0.11848574099679855 4.807442974661034E-48 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 31 7 5032 25 4 false 0.11938248821094233 0.11938248821094233 0.0 T_cell_selection GO:0045058 12133 34 31 1 1618 6 2 false 0.11981626261348999 0.11981626261348999 3.2849261872322015E-71 nucleolar_part GO:0044452 12133 27 31 1 2767 13 2 false 0.11992994554644255 0.11992994554644255 1.4388099017390093E-65 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 31 2 506 2 3 false 0.12191132156696709 0.12191132156696709 1.5079927652081954E-141 miRNA_binding GO:0035198 12133 7 31 1 763 14 1 false 0.1220369318391563 0.1220369318391563 3.4414852859627354E-17 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 31 9 6103 29 3 false 0.12253536204068881 0.12253536204068881 0.0 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 31 3 639 3 3 false 0.12266269311991101 0.12266269311991101 1.399157780258238E-191 bHLH_transcription_factor_binding GO:0043425 12133 23 31 1 715 4 1 false 0.12284028574029406 0.12284028574029406 8.29405091807051E-44 regulation_of_cell_cycle_process GO:0010564 12133 382 31 3 1096 4 2 false 0.1246763452532411 0.1246763452532411 7.137372224746455E-307 cell_fate_commitment_involved_in_formation_of_primary_germ_layer GO:0060795 12133 30 31 1 239 1 2 false 0.12552301255229012 0.12552301255229012 7.886166302670767E-39 fibroblast_growth_factor_binding GO:0017134 12133 17 31 1 135 1 1 false 0.12592592592592816 0.12592592592592816 6.193063943061966E-22 defense_response_to_bacterium GO:0042742 12133 98 31 2 1083 7 2 false 0.12613452826837515 0.12613452826837515 3.52130313437132E-142 regulation_of_MAP_kinase_activity GO:0043405 12133 268 31 3 533 3 3 false 0.12641375435924845 0.12641375435924845 1.0382438249699724E-159 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 31 2 415 2 3 false 0.12662825213904125 0.12662825213904125 9.462933237946419E-117 protein_maturation GO:0051604 12133 123 31 2 5551 28 2 false 0.1268831042075098 0.1268831042075098 1.3126924681575497E-255 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 31 3 1398 5 2 false 0.12830715566673562 0.12830715566673562 0.0 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 31 2 630 2 2 false 0.12946223534461737 0.12946223534461737 4.4826406352842784E-178 regulation_of_calcium-mediated_signaling GO:0050848 12133 29 31 1 1639 8 2 false 0.13335481750972622 0.13335481750972622 6.791382068091653E-63 regulation_of_stem_cell_differentiation GO:2000736 12133 64 31 1 922 2 2 false 0.1340804228169086 0.1340804228169086 2.1519323444963246E-100 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 31 7 504 7 1 false 0.13410101019481088 0.13410101019481088 6.011520399617331E-122 centromere_complex_assembly GO:0034508 12133 33 31 1 705 3 2 false 0.13413637601764414 0.13413637601764414 1.9002913958117045E-57 cofactor_binding GO:0048037 12133 192 31 2 8962 30 1 false 0.13460591764157437 0.13460591764157437 0.0 microtubule_cytoskeleton GO:0015630 12133 734 31 3 1430 3 1 false 0.13496297470255245 0.13496297470255245 0.0 ribosomal_small_subunit_assembly GO:0000028 12133 6 31 1 128 3 3 false 0.1351471691038638 0.1351471691038638 1.8437899825856603E-10 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 31 2 2896 4 3 false 0.1358423872398073 0.1358423872398073 0.0 viral_protein_processing GO:0019082 12133 10 31 2 256 17 2 false 0.13634922286745357 0.13634922286745357 3.5864633505920636E-18 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 31 2 835 3 2 false 0.1365123312065017 0.1365123312065017 8.0742416973675315E-196 positive_regulation_of_catenin_import_into_nucleus GO:0035413 12133 10 31 1 73 1 3 false 0.13698630136986392 0.13698630136986392 1.6094638084594247E-12 cytoplasmic_stress_granule GO:0010494 12133 29 31 1 5117 26 2 false 0.13768471697807683 0.13768471697807683 2.627932865737447E-77 cardiocyte_differentiation GO:0035051 12133 82 31 1 2247 4 2 false 0.13826180258716458 0.13826180258716458 3.1286242033829293E-152 stem_cell_maintenance GO:0019827 12133 93 31 1 4373 7 4 false 0.13978961958962494 0.13978961958962494 7.918520551520462E-195 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 31 2 170 2 3 false 0.14034110685692527 0.14034110685692527 2.004129732487635E-48 regulation_of_cellular_response_to_stress GO:0080135 12133 270 31 2 6503 16 3 false 0.14080107089739669 0.14080107089739669 0.0 response_to_biotic_stimulus GO:0009607 12133 494 31 3 5200 14 1 false 0.14132758044457994 0.14132758044457994 0.0 cell-type_specific_apoptotic_process GO:0097285 12133 270 31 3 1373 7 1 false 0.14180992426446676 0.14180992426446676 9.434604867208542E-295 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 31 2 522 3 3 false 0.1419289912108517 0.1419289912108517 1.2617392241842968E-123 protein_complex_subunit_organization GO:0071822 12133 989 31 19 1256 21 1 false 0.1430998431102407 0.1430998431102407 2.2763776011987297E-281 antigen_processing_and_presentation GO:0019882 12133 185 31 2 1618 6 1 false 0.14326125444908244 0.14326125444908244 5.091289488805967E-249 protein_catabolic_process GO:0030163 12133 498 31 6 3569 26 2 false 0.14394747922184392 0.14394747922184392 0.0 ribosome_assembly GO:0042255 12133 16 31 1 417 4 3 false 0.14536139150895494 0.14536139150895494 3.349634512578164E-29 egress_of_virus_within_host_cell GO:0046788 12133 11 31 2 28 2 2 false 0.14550264550264613 0.14550264550264613 4.656755228837597E-8 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 31 2 269 2 2 false 0.1457304555290202 0.1457304555290202 3.613555574654199E-77 cellular_response_to_organic_substance GO:0071310 12133 1347 31 5 1979 5 2 false 0.14573955205350939 0.14573955205350939 0.0 metal_cluster_binding GO:0051540 12133 47 31 1 8962 30 1 false 0.14615142223068198 0.14615142223068198 5.036293134785758E-127 regulation_of_posttranscriptional_gene_silencing GO:0060147 12133 6 31 1 41 1 2 false 0.1463414634146351 0.1463414634146351 2.2240073587955856E-7 kinetochore_organization GO:0051383 12133 12 31 1 1607 21 2 false 0.14648656385269462 0.14648656385269462 1.682773852302611E-30 coated_pit GO:0005905 12133 52 31 1 10213 31 3 false 0.14655545344040458 0.14655545344040458 3.070128605674566E-141 stem_cell_proliferation GO:0072089 12133 101 31 1 1316 2 1 false 0.14765911218473513 0.14765911218473513 4.366742485719316E-154 maturation_of_SSU-rRNA GO:0030490 12133 8 31 1 104 2 2 false 0.14861837191933652 0.14861837191933652 3.8823564737710265E-12 positive_regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001244 12133 23 31 1 154 1 3 false 0.1493506493506485 0.1493506493506485 7.088148088578188E-28 glycolysis GO:0006096 12133 56 31 1 374 1 2 false 0.14973262032084086 0.14973262032084086 4.51855378952521E-68 MAP_kinase_activity GO:0004707 12133 277 31 3 520 3 2 false 0.15039073565077132 0.15039073565077132 2.5282679507054518E-155 transferase_activity GO:0016740 12133 1779 31 7 4901 13 1 false 0.1518971988642357 0.1518971988642357 0.0 positive_regulation_of_innate_immune_response GO:0045089 12133 178 31 3 740 6 4 false 0.15393217205730883 0.15393217205730883 1.4450011889246649E-176 membrane_raft GO:0045121 12133 163 31 1 2995 3 1 false 0.15459616354073002 0.15459616354073002 3.9757527534590165E-274 SUMO_binding GO:0032183 12133 11 31 1 71 1 1 false 0.15492957746478972 0.15492957746478972 3.905414937502235E-13 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 31 7 2528 11 3 false 0.1560499334501797 0.1560499334501797 0.0 positive_regulation_of_defense_response GO:0031349 12133 229 31 3 1621 10 3 false 0.15710281144709842 0.15710281144709842 6.85443065618377E-286 small_conjugating_protein_ligase_binding GO:0044389 12133 147 31 2 1005 5 1 false 0.15757862113600965 0.15757862113600965 6.302468729220369E-181 positive_regulation_of_immune_response GO:0050778 12133 394 31 4 1600 9 4 false 0.1581966902686595 0.1581966902686595 0.0 protein_lipidation GO:0006497 12133 37 31 1 2373 11 2 false 0.159057708694303 0.159057708694303 2.3726752619035733E-82 lipid_particle GO:0005811 12133 34 31 1 5117 26 1 false 0.15950160702314534 0.15950160702314534 2.5784478668075694E-88 glycoprotein_binding GO:0001948 12133 53 31 1 6397 21 1 false 0.16053241403290558 0.16053241403290558 1.0185621678386298E-132 regulation_of_intrinsic_apoptotic_signaling_pathway GO:2001242 12133 31 31 1 193 1 2 false 0.16062176165802722 0.16062176165802722 1.4758328099403201E-36 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 31 3 1525 9 1 false 0.1608645264142318 0.1608645264142318 1.2095302863090285E-289 regulation_of_reproductive_process GO:2000241 12133 171 31 2 6891 29 2 false 0.16116217341502492 0.16116217341502492 0.0 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 31 8 4429 26 3 false 0.16117698382063572 0.16117698382063572 0.0 regulation_of_catenin_import_into_nucleus GO:0035412 12133 20 31 1 123 1 2 false 0.16260162601625683 0.16260162601625683 1.9835487661021454E-23 positive_regulation_of_calcium-mediated_signaling GO:0050850 12133 21 31 1 828 7 3 false 0.16513889447138405 0.16513889447138405 3.4735570070766575E-42 neurotrophin_signaling_pathway GO:0038179 12133 253 31 2 2018 6 2 false 0.16713630256194487 0.16713630256194487 0.0 activation_of_MAPK_activity GO:0000187 12133 158 31 3 286 3 2 false 0.1671675988948046 0.1671675988948046 8.207976102051858E-85 spindle_assembly GO:0051225 12133 41 31 1 907 4 3 false 0.1691817204444357 0.1691817204444357 4.582948722247768E-72 response_to_growth_factor_stimulus GO:0070848 12133 545 31 3 1783 5 1 false 0.17035954117265265 0.17035954117265265 0.0 heart_induction GO:0003129 12133 7 31 1 41 1 3 false 0.17073170731707424 0.17073170731707424 4.4480147175911587E-8 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 31 2 650 3 2 false 0.17078806316095163 0.17078806316095163 6.010278185218431E-162 extracellular_membrane-bounded_organelle GO:0065010 12133 59 31 1 7284 23 2 false 0.17083952584405315 0.17083952584405315 2.3146567535480854E-148 regulation_of_cell_division GO:0051302 12133 75 31 1 6427 16 2 false 0.17141105666013418 0.17141105666013418 9.599183496643589E-177 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 31 8 4298 26 4 false 0.17149310190610878 0.17149310190610878 0.0 clathrin_vesicle_coat GO:0030125 12133 20 31 1 116 1 3 false 0.1724137931034499 0.1724137931034499 7.110456703810784E-23 SUMO_ligase_activity GO:0019789 12133 9 31 1 335 7 1 false 0.17501138861289775 0.17501138861289775 7.610794818623194E-18 regulation_of_interleukin-2_biosynthetic_process GO:0045076 12133 17 31 1 97 1 3 false 0.1752577319587615 0.1752577319587615 2.6463900392336375E-19 condensed_nuclear_chromosome GO:0000794 12133 64 31 1 363 1 2 false 0.1763085399449078 0.1763085399449078 6.85090242714841E-73 double-stranded_RNA_binding GO:0003725 12133 42 31 2 763 14 1 false 0.17725072660579314 0.17725072660579314 3.809412344480898E-70 neuron_death GO:0070997 12133 170 31 2 1525 7 1 false 0.17854396643861403 0.17854396643861403 9.045134214386945E-231 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 31 2 183 2 2 false 0.18032786885244478 0.18032786885244478 1.0111677973178846E-53 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 31 6 6622 17 1 false 0.18036957186837382 0.18036957186837382 0.0 leading_edge_membrane GO:0031256 12133 93 31 1 1450 3 2 false 0.18045296609768569 0.18045296609768569 2.320023810279922E-149 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 31 2 217 4 1 false 0.18364127079832696 0.18364127079832696 4.514459380304185E-47 regulation_of_organ_morphogenesis GO:2000027 12133 133 31 1 1378 2 3 false 0.18378123705567792 0.18378123705567792 3.250421699031885E-189 cell_cycle_arrest GO:0007050 12133 202 31 2 998 4 2 false 0.18419960366416965 0.18419960366416965 1.5077994882682823E-217 SMAD_protein_import_into_nucleus GO:0007184 12133 16 31 1 402 5 2 false 0.1846294700483104 0.1846294700483104 6.086139815551782E-29 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 31 2 201 4 3 false 0.18541781726359863 0.18541781726359863 9.949481941404742E-44 regulation_of_innate_immune_response GO:0045088 12133 226 31 3 868 6 3 false 0.18550558121572458 0.18550558121572458 2.196344369914344E-215 carbon-oxygen_lyase_activity GO:0016835 12133 43 31 1 230 1 1 false 0.18695652173911087 0.18695652173911087 1.1165562295399568E-47 interleukin-2_biosynthetic_process GO:0042094 12133 20 31 1 106 1 2 false 0.188679245283022 0.188679245283022 5.142035106935522E-22 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 31 3 912 4 2 false 0.19181994038116423 0.19181994038116423 2.059888800891414E-267 positive_regulation_of_molecular_function GO:0044093 12133 1303 31 6 10257 31 2 false 0.19328515545140112 0.19328515545140112 0.0 cytoplasmic_vesicle_part GO:0044433 12133 366 31 3 7185 30 3 false 0.19473934334941664 0.19473934334941664 0.0 organelle_envelope_lumen GO:0031970 12133 43 31 1 5320 27 3 false 0.1972076909335132 0.1972076909335132 4.373804248541692E-108 extracellular_organelle GO:0043230 12133 59 31 1 8358 31 2 false 0.19748504340533726 0.19748504340533726 6.7158083402639515E-152 positive_regulation_of_cytokine_biosynthetic_process GO:0042108 12133 54 31 1 1741 7 5 false 0.19823688226945593 0.19823688226945593 5.2585096848750585E-104 regulation_of_immune_response GO:0050776 12133 533 31 4 2461 11 3 false 0.19926004486532672 0.19926004486532672 0.0 protein_K6-linked_ubiquitination GO:0085020 12133 7 31 1 163 5 1 false 0.19930625804897323 0.19930625804897323 1.878573514862509E-12 regulation_of_microtubule-based_process GO:0032886 12133 89 31 1 6442 16 2 false 0.19976666006194047 0.19976666006194047 3.020423949382438E-203 evasion_or_tolerance_of_host_immune_response GO:0020012 12133 1 31 1 5 1 3 false 0.19999999999999996 0.19999999999999996 0.19999999999999996 peptidyl-cysteine_S-trans-nitrosylation GO:0035606 12133 1 31 1 5 1 1 false 0.19999999999999996 0.19999999999999996 0.19999999999999996 evasion_or_tolerance_of_immune_response_of_other_organism_involved_in_symbiotic_interaction GO:0051805 12133 1 31 1 5 1 2 false 0.19999999999999996 0.19999999999999996 0.19999999999999996 transcription_factor_binding GO:0008134 12133 715 31 4 6397 21 1 false 0.20154411012793844 0.20154411012793844 0.0 lymphocyte_costimulation GO:0031294 12133 60 31 1 1618 6 2 false 0.20314701461125875 0.20314701461125875 7.286021331162317E-111 protein_K63-linked_ubiquitination GO:0070534 12133 28 31 2 163 5 1 false 0.20422951361453845 0.20422951361453845 4.092462206953933E-32 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 31 2 195 3 4 false 0.2050416438964213 0.2050416438964213 1.081664723883568E-50 regulation_of_translation GO:0006417 12133 210 31 3 3605 27 4 false 0.20572549689243405 0.20572549689243405 0.0 negative_regulation_of_signaling GO:0023057 12133 597 31 3 4884 13 3 false 0.20603538023323464 0.20603538023323464 0.0 catenin_import_into_nucleus GO:0035411 12133 22 31 1 200 2 1 false 0.2083919597989768 0.2083919597989768 8.8863587295584E-30 small_conjugating_protein_binding GO:0032182 12133 71 31 1 6397 21 1 false 0.2092317639014242 0.2092317639014242 7.493300865579233E-169 heart_morphogenesis GO:0003007 12133 162 31 1 774 1 2 false 0.20930232558134837 0.20930232558134837 1.0020458463027537E-171 negative_regulation_of_cell_communication GO:0010648 12133 599 31 3 4860 13 3 false 0.20958014001206438 0.20958014001206438 0.0 regulation_of_defense_response GO:0031347 12133 387 31 4 1253 8 2 false 0.20985228033357473 0.20985228033357473 0.0 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 31 4 1541 8 3 false 0.21003043894779816 0.21003043894779816 0.0 regulation_of_cell_cycle GO:0051726 12133 659 31 3 6583 16 2 false 0.21104271799838326 0.21104271799838326 0.0 organelle_assembly GO:0070925 12133 210 31 2 2677 11 2 false 0.2114904764313492 0.2114904764313492 7.5039E-319 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I GO:0042590 12133 73 31 2 158 2 2 false 0.21188422155928965 0.21188422155928965 6.794891168245598E-47 activation_of_innate_immune_response GO:0002218 12133 155 31 3 362 4 2 false 0.21191280677554653 0.21191280677554653 1.0665156090103768E-106 membrane_coat GO:0030117 12133 66 31 1 7525 27 4 false 0.212009269667399 0.212009269667399 1.024710613883824E-163 regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033143 12133 43 31 1 1642 9 2 false 0.2129164344154671 0.2129164344154671 5.767987369966462E-86 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 31 2 759 7 3 false 0.21460465880977522 0.21460465880977522 1.1458874617943115E-123 DNA_metabolic_process GO:0006259 12133 791 31 6 5627 29 2 false 0.21461829006400196 0.21461829006400196 0.0 damaged_DNA_binding GO:0003684 12133 50 31 1 2091 10 1 false 0.21537878036690203 0.21537878036690203 5.270282333276611E-102 negative_regulation_of_viral_reproduction GO:0048525 12133 28 31 1 2903 25 4 false 0.21597349484094194 0.21597349484094194 3.8119989558045655E-68 positive_regulation_of_interleukin-2_biosynthetic_process GO:0045086 12133 13 31 1 60 1 3 false 0.21666666666666876 0.21666666666666876 1.935410165204454E-13 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 31 3 129 3 1 false 0.2176684673136865 0.2176684673136865 3.5310664374642874E-37 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 31 2 929 3 2 false 0.2188569736891108 0.2188569736891108 1.7613668775256747E-246 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 31 2 134 2 2 false 0.21916732128828628 0.21916732128828628 8.460684206886756E-40 nucleosome GO:0000786 12133 61 31 1 519 2 3 false 0.22145349312977564 0.22145349312977564 4.729950878459035E-81 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 31 8 3780 26 4 false 0.2248319690762393 0.2248319690762393 0.0 enzyme_binding GO:0019899 12133 1005 31 5 6397 21 1 false 0.22509861820348187 0.22509861820348187 0.0 positive_regulation_of_cytokine_production GO:0001819 12133 175 31 3 614 6 3 false 0.22761502176016643 0.22761502176016643 1.2195240299259301E-158 regulation_of_MAPK_cascade GO:0043408 12133 429 31 3 701 3 2 false 0.22857867056859496 0.22857867056859496 1.5434745144062482E-202 protein_phosphatase_regulator_activity GO:0019888 12133 49 31 1 214 1 2 false 0.2289719626168252 0.2289719626168252 1.5290549326601881E-49 cellular_component GO:0005575 12133 10701 31 31 11221 31 1 false 0.22924542411722967 0.22924542411722967 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 31 2 6813 19 2 false 0.22988547290565542 0.22988547290565542 0.0 BMP_signaling_pathway_involved_in_heart_induction GO:0003130 12133 3 31 1 13 1 3 false 0.23076923076923084 0.23076923076923084 0.0034965034965034974 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 31 2 2943 11 3 false 0.23295979208513343 0.23295979208513343 0.0 regulation_of_receptor_activity GO:0010469 12133 89 31 1 3057 9 3 false 0.23376414586346647 0.23376414586346647 3.874143452259453E-174 membrane_budding GO:0006900 12133 38 31 1 2595 18 4 false 0.2338773172852438 0.2338773172852438 1.2575474095115043E-85 regulation_of_cell_fate_specification GO:0042659 12133 16 31 1 68 1 2 false 0.23529411764705738 0.23529411764705738 6.804717202532545E-16 positive_regulation_of_endopeptidase_activity GO:0010950 12133 112 31 1 476 1 3 false 0.23529411764709918 0.23529411764709918 3.786215967470695E-112 ER-nucleus_signaling_pathway GO:0006984 12133 94 31 1 3547 10 1 false 0.2358059795395181 0.2358059795395181 7.751301219638514E-188 protein_deacylation GO:0035601 12133 58 31 1 2370 11 1 false 0.23900688687336133 0.23900688687336133 8.732809717864973E-118 hydrolase_activity,_acting_on_ester_bonds GO:0016788 12133 814 31 2 2556 3 1 false 0.23957164354070903 0.23957164354070903 0.0 regulation_of_peptidase_activity GO:0052547 12133 276 31 1 1151 1 2 false 0.23979148566463482 0.23979148566463482 1.6233323078676786E-274 regulation_of_gene_silencing_by_miRNA GO:0060964 12133 6 31 1 25 1 3 false 0.24000000000000046 0.24000000000000046 5.646527385657787E-6 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 31 2 130 2 2 false 0.2404293381037601 0.2404293381037601 1.0680656075518395E-38 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 31 2 442 2 3 false 0.24046541693606321 0.24046541693606321 2.4953498472018727E-132 MAPK_cascade GO:0000165 12133 502 31 3 806 3 1 false 0.24105962489080368 0.24105962489080368 3.7900857366173457E-231 regulation_of_organ_formation GO:0003156 12133 36 31 1 149 1 2 false 0.24161073825504298 0.24161073825504298 2.1790645078572627E-35 non-membrane_spanning_protein_tyrosine_kinase_activity GO:0004715 12133 44 31 1 180 1 1 false 0.24444444444443322 0.24444444444443322 4.841672635603901E-43 movement_in_host_environment GO:0052126 12133 21 31 1 387 5 2 false 0.24455729537809648 0.24455729537809648 4.0397291631939195E-35 monosaccharide_biosynthetic_process GO:0046364 12133 62 31 1 253 1 2 false 0.24505928853752568 0.24505928853752568 1.1247044052233336E-60 protein_N-terminus_binding GO:0047485 12133 85 31 1 6397 21 1 false 0.24523626496863907 0.24523626496863907 1.5319897739448716E-195 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 31 3 178 3 1 false 0.24661969148737378 0.24661969148737378 1.7238002808689451E-50 negative_regulation_of_translation GO:0017148 12133 61 31 2 1470 23 4 false 0.24679747863176987 0.24679747863176987 1.1152524521517982E-109 formation_of_translation_initiation_complex GO:0001732 12133 4 31 1 249 17 2 false 0.2477188238967937 0.2477188238967937 6.396290110799597E-9 hormone_receptor_binding GO:0051427 12133 122 31 1 918 2 1 false 0.24825910007774046 0.24825910007774046 1.5301276126382055E-155 cellular_protein_complex_assembly GO:0043623 12133 284 31 3 958 6 2 false 0.2486458128884505 0.2486458128884505 4.57678794545446E-252 cellular_response_to_topologically_incorrect_protein GO:0035967 12133 87 31 1 2172 7 3 false 0.2491587883511222 0.2491587883511222 5.95891199322288E-158 negative_regulation_of_signal_transduction GO:0009968 12133 571 31 3 3588 11 5 false 0.24921720036541598 0.24921720036541598 0.0 endonucleolytic_cleavage_to_generate_mature_3'-end_of_SSU-rRNA_from_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000461 12133 2 31 1 8 1 3 false 0.24999999999999994 0.24999999999999994 0.035714285714285705 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 31 3 129 3 1 false 0.253387657938109 0.253387657938109 2.4714073881998435E-36 DNA-(apurinic_or_apyrimidinic_site)_lyase_activity GO:0003906 12133 11 31 1 43 1 1 false 0.25581395348837 0.25581395348837 1.738524415708855E-10 clathrin_coat_of_endocytic_vesicle GO:0030128 12133 9 31 1 35 1 2 false 0.2571428571428579 0.2571428571428579 1.4162809425519529E-8 oxidation-reduction_process GO:0055114 12133 740 31 1 2877 1 1 false 0.2572123740010639 0.2572123740010639 0.0 protein_localization GO:0008104 12133 1434 31 19 1642 20 1 false 0.2580219929178529 0.2580219929178529 3.426309620265761E-270 defense_response_to_virus GO:0051607 12133 160 31 2 1130 7 3 false 0.2598208083378447 0.2598208083378447 2.076664675339186E-199 regulation_of_cell_death GO:0010941 12133 1062 31 4 6437 16 2 false 0.26439936706857153 0.26439936706857153 0.0 microtubule_associated_complex GO:0005875 12133 110 31 1 3267 9 3 false 0.2655504217656697 0.2655504217656697 2.821671595839563E-208 endoderm_formation GO:0001706 12133 24 31 1 90 1 2 false 0.2666666666666713 0.2666666666666713 2.273233616090178E-22 regulation_of_cytokine_biosynthetic_process GO:0042035 12133 80 31 1 3656 14 5 false 0.26677698550640455 0.26677698550640455 1.557250442043908E-166 negative_regulation_of_cellular_process GO:0048523 12133 2515 31 10 9689 31 3 false 0.26869797717385613 0.26869797717385613 0.0 tubulin_binding GO:0015631 12133 150 31 1 556 1 1 false 0.2697841726618369 0.2697841726618369 4.293395323631497E-140 response_to_abiotic_stimulus GO:0009628 12133 676 31 3 5200 14 1 false 0.27065626800730735 0.27065626800730735 0.0 vesicle_coat GO:0030120 12133 38 31 1 381 3 3 false 0.2710011842187785 0.2710011842187785 2.9673810590707202E-53 extracellular_vesicular_exosome GO:0070062 12133 58 31 1 763 4 2 false 0.27158906822018636 0.27158906822018636 1.4131645972383266E-88 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 31 8 3453 26 4 false 0.2725259975684512 0.2725259975684512 0.0 lipoprotein_biosynthetic_process GO:0042158 12133 42 31 1 3412 26 2 false 0.27618983193247926 0.27618983193247926 7.435979921136148E-98 hexose_biosynthetic_process GO:0019319 12133 57 31 1 206 1 2 false 0.2766990291262256 0.2766990291262256 2.7565278967151444E-52 negative_regulation_of_biological_process GO:0048519 12133 2732 31 10 10446 31 2 false 0.2772362748185671 0.2772362748185671 0.0 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 31 2 381 2 2 false 0.2776626605885186 0.2776626605885186 8.855041133991382E-114 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 31 2 599 4 2 false 0.27912889848581784 0.27912889848581784 1.7219296535416308E-148 vesicle_organization GO:0016050 12133 93 31 1 2031 7 1 false 0.28006881634915587 0.28006881634915587 2.372545997452078E-163 DNA-directed_RNA_polymerase_activity GO:0003899 12133 39 31 1 2751 23 2 false 0.280879548576567 0.280879548576567 1.9363403456708335E-88 regulatory_region_DNA_binding GO:0000975 12133 1169 31 7 2091 10 2 false 0.2850939118833907 0.2850939118833907 0.0 external_side_of_plasma_membrane GO:0009897 12133 154 31 1 1452 3 2 false 0.2858036291041428 0.2858036291041428 1.5920516906253226E-212 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 31 2 1097 9 3 false 0.2865259713057655 0.2865259713057655 8.208279871491876E-172 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 31 2 673 2 2 false 0.28735937168333336 0.28735937168333336 4.9348138289436974E-201 cilium_part GO:0044441 12133 69 31 1 5535 27 4 false 0.2878765645899842 0.2878765645899842 1.3900483239048332E-160 cell_cycle_phase GO:0022403 12133 253 31 2 953 4 1 false 0.2879036989487487 0.2879036989487487 1.0384727319913012E-238 gastrulation GO:0007369 12133 117 31 1 406 1 1 false 0.2881773399014751 0.2881773399014751 2.9879060124816245E-105 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_I GO:0002474 12133 88 31 2 163 2 1 false 0.2899341058849978 0.2899341058849978 2.2957799692832176E-48 positive_regulation_of_biological_process GO:0048518 12133 3081 31 11 10446 31 2 false 0.289959356650679 0.289959356650679 0.0 negative_regulation_of_viral_genome_replication GO:0045071 12133 27 31 1 93 1 4 false 0.2903225806451571 0.2903225806451571 5.123998834104114E-24 negative_regulation_of_DNA_metabolic_process GO:0051053 12133 58 31 1 1888 11 4 false 0.2911773258215603 0.2911773258215603 5.587452620659773E-112 gluconeogenesis GO:0006094 12133 54 31 1 185 1 2 false 0.2918918918919016 0.2918918918919016 4.74373526943691E-48 heart_field_specification GO:0003128 12133 12 31 1 41 1 2 false 0.2926829268292705 0.2926829268292705 1.266038344665403E-10 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 31 2 116 2 3 false 0.2928035982009022 0.2928035982009022 2.4978330889301296E-34 positive_regulation_of_apoptotic_signaling_pathway GO:2001235 12133 47 31 1 973 7 3 false 0.2936676580157305 0.2936676580157305 2.8956045317480326E-81 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 31 3 305 4 2 false 0.29419348391070643 0.29419348391070643 3.640759676212702E-91 receptor_complex GO:0043235 12133 146 31 1 2976 7 1 false 0.29706329371593615 0.29706329371593615 3.091225804524361E-252 ATP_binding GO:0005524 12133 1212 31 4 1638 4 3 false 0.29936071055097485 0.29936071055097485 0.0 RNA_3'-end_processing GO:0031123 12133 98 31 1 601 2 1 false 0.2997615085968001 0.2997615085968001 1.9130441150898719E-115 DNA_damage_checkpoint GO:0000077 12133 126 31 2 574 5 2 false 0.3028741595057191 0.3028741595057191 1.5833464450994651E-130 positive_regulation_of_stress-activated_protein_kinase_signaling_cascade GO:0070304 12133 61 31 1 539 3 3 false 0.30303992284019055 0.30303992284019055 4.088710484286359E-82 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 31 3 1356 5 2 false 0.3040020562414041 0.3040020562414041 0.0 signal_transduction GO:0007165 12133 3547 31 10 6702 16 4 false 0.3044593000829655 0.3044593000829655 0.0 clathrin-coated_endocytic_vesicle GO:0045334 12133 31 31 1 272 3 2 false 0.30541687769815945 0.30541687769815945 1.6415618681542047E-41 cytokine-mediated_signaling_pathway GO:0019221 12133 318 31 2 2013 7 2 false 0.3057248723790234 0.3057248723790234 0.0 sequence-specific_DNA_binding GO:0043565 12133 1189 31 7 2091 10 1 false 0.3065413854345159 0.3065413854345159 0.0 G1_DNA_damage_checkpoint GO:0044783 12133 70 31 2 126 2 1 false 0.30666666666666786 0.30666666666666786 3.590272155218709E-37 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 31 1 1881 5 2 false 0.31119164934293764 0.31119164934293764 3.367676499542027E-210 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 31 7 2643 11 1 false 0.3123418052793837 0.3123418052793837 0.0 cell_fate_commitment GO:0045165 12133 203 31 1 2267 4 2 false 0.3130588716153479 0.3130588716153479 5.088065815511718E-296 adenyl_ribonucleotide_binding GO:0032559 12133 1231 31 4 1645 4 2 false 0.31320954047549715 0.31320954047549715 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 31 4 1650 4 1 false 0.31347325632894396 0.31347325632894396 0.0 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 31 2 53 2 2 false 0.31567489114658837 0.31567489114658837 1.6040955778771873E-15 regulation_of_protein_localization_to_nucleus GO:1900180 12133 125 31 1 722 2 3 false 0.3164848759611147 0.3164848759611147 8.18717732691146E-144 RNA_polymerase_activity GO:0034062 12133 39 31 1 123 1 1 false 0.3170731707317023 0.3170731707317023 5.565765306949106E-33 negative_regulation_of_cell_cycle GO:0045786 12133 298 31 2 3131 12 3 false 0.3187855600390487 0.3187855600390487 0.0 regulation_of_microtubule_cytoskeleton_organization GO:0070507 12133 76 31 1 435 2 3 false 0.3192330102229589 0.3192330102229589 5.9731911660851205E-87 ruffle GO:0001726 12133 119 31 1 990 3 2 false 0.3192796196759389 0.3192796196759389 2.995179002772035E-157 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 31 1 1014 4 1 false 0.3198157339218555 0.3198157339218555 2.468210871514413E-134 protein_kinase_activity GO:0004672 12133 1014 31 4 1347 4 3 false 0.32066005283062343 0.32066005283062343 0.0 transcription_elongation_from_RNA_polymerase_II_promoter GO:0006368 12133 75 31 1 1386 7 2 false 0.3231404324191566 0.3231404324191566 4.445398870391459E-126 posttranscriptional_gene_silencing GO:0016441 12133 28 31 1 444 6 3 false 0.325058540721369 0.325058540721369 5.432926029416489E-45 ion_transmembrane_transport GO:0034220 12133 556 31 2 970 2 2 false 0.32830104369452756 0.32830104369452756 1.3121997139332702E-286 regulation_of_response_to_biotic_stimulus GO:0002831 12133 80 31 1 2255 11 2 false 0.32849535864377594 0.32849535864377594 1.6552927666708391E-149 negative_regulation_of_multi-organism_process GO:0043901 12133 51 31 1 3360 26 3 false 0.32912135085051175 0.32912135085051175 3.258164733926273E-114 protein_sumoylation GO:0016925 12133 32 31 1 578 7 1 false 0.3302362120417018 0.3302362120417018 2.618927943730716E-53 maintenance_of_location_in_cell GO:0051651 12133 100 31 1 7542 30 3 false 0.33049063653059957 0.33049063653059957 3.2184799576057033E-230 nuclear_lumen GO:0031981 12133 2490 31 13 3186 15 2 false 0.3315555743315747 0.3315555743315747 0.0 protein_destabilization GO:0031648 12133 18 31 1 99 2 1 false 0.33209647495360395 0.33209647495360395 3.976949780666304E-20 evasion_or_tolerance_of_host_defense_response GO:0030682 12133 1 31 1 3 1 2 false 0.33333333333333337 0.33333333333333337 0.33333333333333337 evasion_or_tolerance_by_virus_of_host_immune_response GO:0030683 12133 1 31 1 3 1 2 false 0.33333333333333337 0.33333333333333337 0.33333333333333337 MHC_class_II_protein_binding GO:0042289 12133 9 31 1 27 1 1 false 0.33333333333333354 0.33333333333333354 2.133640577576491E-7 regulation_of_protein_ubiquitination GO:0031396 12133 176 31 2 1344 9 2 false 0.3338724508863661 0.3338724508863661 8.0617715234352E-226 calcium-mediated_signaling GO:0019722 12133 86 31 1 257 1 1 false 0.33463035019455556 0.33463035019455556 1.363801895693069E-70 defense_response_to_Gram-negative_bacterium GO:0050829 12133 18 31 1 98 2 1 false 0.3351567431096045 0.3351567431096045 4.860716398592285E-20 death GO:0016265 12133 1528 31 7 8052 30 1 false 0.3383039096802126 0.3383039096802126 0.0 execution_phase_of_apoptosis GO:0097194 12133 103 31 1 7541 30 2 false 0.33859242234761405 0.33859242234761405 8.404030944176242E-236 activation_of_MAPKK_activity GO:0000186 12133 64 31 1 496 3 3 false 0.3398910088215636 0.3398910088215636 2.7437381948522894E-82 response_to_topologically_incorrect_protein GO:0035966 12133 133 31 1 3273 10 2 false 0.3399406113545117 0.3399406113545117 7.334457285081863E-241 transferase_activity,_transferring_pentosyl_groups GO:0016763 12133 41 31 1 120 1 1 false 0.3416666666666674 0.3416666666666674 4.473761349509658E-33 immune_system_development GO:0002520 12133 521 31 2 3460 8 2 false 0.34467267694705245 0.34467267694705245 0.0 protein_autoubiquitination GO:0051865 12133 32 31 1 548 7 1 false 0.34529839384845046 0.34529839384845046 1.513679138085879E-52 immune_system_process GO:0002376 12133 1618 31 6 10446 31 1 false 0.34570690940967297 0.34570690940967297 0.0 regulation_of_catalytic_activity GO:0050790 12133 1692 31 5 6953 16 3 false 0.34587704765543525 0.34587704765543525 0.0 nucleoplasm GO:0005654 12133 1443 31 8 2767 13 2 false 0.34639630265589516 0.34639630265589516 0.0 activation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0006919 12133 81 31 1 1375 7 3 false 0.34686268246921154 0.34686268246921154 4.023711257429167E-133 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 31 4 1546 7 3 false 0.34718508503946255 0.34718508503946255 0.0 signal_transducer_activity GO:0004871 12133 1070 31 4 3547 10 2 false 0.3547250788401447 0.3547250788401447 0.0 glucose_catabolic_process GO:0006007 12133 68 31 1 191 1 2 false 0.3560209424083976 0.3560209424083976 1.6292167386385306E-53 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 31 1 1679 7 3 false 0.3585206720292864 0.3585206720292864 1.5952227787322578E-167 growth_factor_binding GO:0019838 12133 135 31 1 6397 21 1 false 0.3614970060035334 0.3614970060035334 1.7435678435075742E-283 SUMO_polymer_binding GO:0032184 12133 4 31 1 11 1 1 false 0.36363636363636415 0.36363636363636415 0.003030303030303028 vesicle_coating GO:0006901 12133 34 31 1 93 1 2 false 0.3655913978494587 0.3655913978494587 3.5394863741255215E-26 monosaccharide_catabolic_process GO:0046365 12133 82 31 1 224 1 2 false 0.36607142857142033 0.36607142857142033 2.289161155703443E-63 large_ribosomal_subunit GO:0015934 12133 73 31 10 132 16 1 false 0.36635669606886123 0.36635669606886123 5.5437540818743186E-39 positive_regulation_of_nucleocytoplasmic_transport GO:0046824 12133 75 31 1 367 2 3 false 0.3674007236342441 0.3674007236342441 3.7707577442500014E-80 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 31 3 982 3 1 false 0.3680090724980044 0.3680090724980044 2.6984349291053464E-253 RNA_polymerase_complex GO:0030880 12133 136 31 1 9248 31 2 false 0.3687288478786189 0.3687288478786189 4.112311514468251E-307 MAP_kinase_kinase_activity GO:0004708 12133 74 31 1 521 3 3 false 0.36905141888598725 0.36905141888598725 6.903948166738437E-92 estrogen_receptor_binding GO:0030331 12133 23 31 1 62 1 1 false 0.3709677419354874 0.3709677419354874 1.6756493074771417E-17 ribonucleoprotein_complex_assembly GO:0022618 12133 117 31 2 646 7 3 false 0.3709763770305571 0.3709763770305571 4.631331466925404E-132 hexose_catabolic_process GO:0019320 12133 78 31 1 209 1 2 false 0.3732057416268218 0.3732057416268218 1.9037581511122798E-59 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 31 2 217 2 2 false 0.37455197132611834 0.37455197132611834 2.2668758893633536E-62 avoidance_of_host_defenses GO:0044413 12133 3 31 1 8 1 2 false 0.3749999999999999 0.3749999999999999 0.017857142857142835 avoidance_of_defenses_of_other_organism_involved_in_symbiotic_interaction GO:0051832 12133 3 31 1 8 1 1 false 0.3749999999999999 0.3749999999999999 0.017857142857142835 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 31 1 2191 9 3 false 0.37694905351796826 0.37694905351796826 2.495063769189982E-191 regulation_of_DNA_repair GO:0006282 12133 46 31 1 508 5 3 false 0.3790812233625401 0.3790812233625401 1.525242689490639E-66 negative_regulation_of_molecular_function GO:0044092 12133 735 31 3 10257 31 2 false 0.38521567561404324 0.38521567561404324 0.0 SH3_domain_binding GO:0017124 12133 105 31 1 486 2 1 false 0.38577065037539837 0.38577065037539837 1.6190468269923415E-109 endonuclease_activity GO:0004519 12133 76 31 1 197 1 1 false 0.3857868020304401 0.3857868020304401 1.5249800288122344E-56 stem_cell_development GO:0048864 12133 191 31 1 1273 3 2 false 0.38621588474597024 0.38621588474597024 5.877761968359015E-233 somatic_stem_cell_maintenance GO:0035019 12133 36 31 1 93 1 1 false 0.3870967741935424 0.3870967741935424 1.303259155873185E-26 transferase_activity,_transferring_glycosyl_groups GO:0016757 12133 120 31 1 1779 7 1 false 0.3871964005676505 0.3871964005676505 3.8700015520954533E-190 early_endosome GO:0005769 12133 167 31 3 455 6 1 false 0.3872046608305421 0.3872046608305421 3.2726776377044107E-129 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 31 6 3631 24 4 false 0.38773339298262866 0.38773339298262866 0.0 protein_monoubiquitination GO:0006513 12133 37 31 1 548 7 1 false 0.38868172421333913 0.38868172421333913 2.2069453336747442E-58 positive_regulation_of_stress-activated_MAPK_cascade GO:0032874 12133 60 31 1 397 3 4 false 0.3891547557969134 0.3891547557969134 1.0807496408600027E-72 cilium GO:0005929 12133 161 31 1 7595 23 2 false 0.38952769600616177 0.38952769600616177 0.0 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 31 4 3605 27 4 false 0.3907666289864349 0.3907666289864349 0.0 nucleotidyltransferase_activity GO:0016779 12133 123 31 1 1304 5 1 false 0.3911450753861123 0.3911450753861123 3.0641101871346933E-176 positive_regulation_of_chemokine_production GO:0032722 12133 29 31 1 191 3 3 false 0.3915679250482416 0.3915679250482416 5.88047963496205E-35 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 31 3 7293 23 3 false 0.3927493229905602 0.3927493229905602 0.0 negative_regulation_of_reproductive_process GO:2000242 12133 65 31 1 3420 26 3 false 0.39392933617184905 0.39392933617184905 2.9542142879788904E-139 dephosphorylation GO:0016311 12133 328 31 1 2776 4 1 false 0.3954365000684697 0.3954365000684697 0.0 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 31 2 254 4 3 false 0.3956712708202845 0.3956712708202845 3.7262148804586973E-69 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 31 6 2595 11 2 false 0.3960053731724855 0.3960053731724855 0.0 intracellular_protein_kinase_cascade GO:0007243 12133 806 31 3 1813 5 1 false 0.39679960024137045 0.39679960024137045 0.0 heart_development GO:0007507 12133 343 31 1 2876 4 3 false 0.39846287342598796 0.39846287342598796 0.0 positive_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090100 12133 57 31 1 918 8 3 false 0.4024120202647475 0.4024120202647475 3.1386577853752424E-92 cell_death GO:0008219 12133 1525 31 7 7542 30 2 false 0.4048452425075799 0.4048452425075799 0.0 ribonucleoprotein_granule GO:0035770 12133 75 31 1 3365 23 2 false 0.4055691516319948 0.4055691516319948 1.704323678285534E-155 T_cell_costimulation GO:0031295 12133 59 31 1 145 1 2 false 0.40689655172412764 0.40689655172412764 4.1748509083178786E-42 lipoprotein_metabolic_process GO:0042157 12133 68 31 1 3431 26 1 false 0.40690553007205826 0.40690553007205826 1.8884569574824633E-144 molecular_transducer_activity GO:0060089 12133 1070 31 4 10257 31 1 false 0.40779315190197735 0.40779315190197735 0.0 protein_phosphatase_type_2A_regulator_activity GO:0008601 12133 20 31 1 49 1 1 false 0.40816326530612645 0.40816326530612645 3.536377094612393E-14 vesicle GO:0031982 12133 834 31 4 7980 31 1 false 0.4092116805332284 0.4092116805332284 0.0 positive_regulation_of_cellular_process GO:0048522 12133 2811 31 10 9694 31 3 false 0.409530215121705 0.409530215121705 0.0 positive_regulation_of_protein_modification_process GO:0031401 12133 708 31 4 2417 11 3 false 0.40963718951840683 0.40963718951840683 0.0 modulation_by_virus_of_host_morphology_or_physiology GO:0044792 12133 13 31 2 20 2 1 false 0.4105263157894751 0.4105263157894751 1.2899896800825618E-5 T_cell_differentiation GO:0030217 12133 140 31 1 341 1 2 false 0.4105571847507756 0.4105571847507756 1.226864280824078E-99 regulation_of_viral_transcription GO:0046782 12133 61 31 1 2689 23 4 false 0.4113718818661657 0.4113718818661657 6.28444466749328E-126 DNA_integrity_checkpoint GO:0031570 12133 130 31 2 202 2 1 false 0.41303384069746746 0.41303384069746746 1.23666756413938E-56 chromatin_assembly_or_disassembly GO:0006333 12133 126 31 1 539 2 1 false 0.4132187515089518 0.4132187515089518 1.2574164838803103E-126 DNA_packaging GO:0006323 12133 135 31 1 7668 30 3 false 0.4136820045294104 0.4136820045294104 3.2587442798347094E-294 positive_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043280 12133 101 31 1 1376 7 3 false 0.41424569922224425 0.41424569922224425 4.055423334241229E-156 regulation_of_interleukin-2_production GO:0032663 12133 33 31 1 327 5 2 false 0.4145463164219776 0.4145463164219776 4.834102143986747E-46 rRNA_metabolic_process GO:0016072 12133 107 31 1 258 1 1 false 0.4147286821705359 0.4147286821705359 1.860360860420455E-75 nuclear_body GO:0016604 12133 272 31 2 805 4 1 false 0.41551948572068936 0.41551948572068936 8.12188174084084E-223 cysteine-type_endopeptidase_activity GO:0004197 12133 219 31 1 527 1 2 false 0.4155597722959447 0.4155597722959447 1.229090165658057E-154 peptidyl-cysteine_S-nitrosylation GO:0018119 12133 5 31 1 12 1 2 false 0.41666666666666613 0.41666666666666613 0.001262626262626259 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 31 2 541 3 2 false 0.41838125492735057 0.41838125492735057 1.01164377942614E-160 lymphocyte_differentiation GO:0030098 12133 203 31 1 485 1 2 false 0.4185567010308444 0.4185567010308444 1.747932496277033E-142 pattern_specification_process GO:0007389 12133 326 31 1 4373 7 3 false 0.4188236725600164 0.4188236725600164 0.0 regulation_of_viral_genome_replication GO:0045069 12133 43 31 1 181 2 3 false 0.4197053406997896 0.4197053406997896 1.1493804978494703E-42 clathrin-coated_endocytic_vesicle_membrane GO:0030669 12133 26 31 1 157 3 3 false 0.42130675981094745 0.42130675981094745 2.9127380680410067E-30 chromosome_segregation GO:0007059 12133 136 31 1 7541 30 1 false 0.4213414946915143 0.4213414946915143 5.819868354628029E-295 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 31 4 3910 27 3 false 0.42416191536419007 0.42416191536419007 0.0 positive_regulation_of_viral_reproduction GO:0048524 12133 75 31 1 3144 23 4 false 0.4272410676942665 0.4272410676942665 2.949907770701524E-153 positive_regulation_of_multi-organism_process GO:0043902 12133 79 31 1 3594 25 3 false 0.42738477436632394 0.42738477436632394 2.7290707848948588E-164 protein-DNA_complex_assembly GO:0065004 12133 126 31 2 538 6 2 false 0.4285970458937021 0.4285970458937021 1.6410350721824938E-126 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 31 3 309 4 2 false 0.43352496749598646 0.43352496749598646 7.558729588417702E-91 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 31 16 106 16 2 false 0.43367760112906195 0.43367760112906195 9.867686559172291E-9 endoplasmic_reticulum_lumen GO:0005788 12133 125 31 1 3346 15 2 false 0.435789234983901 0.435789234983901 5.341455344292604E-231 interleukin-2_production GO:0032623 12133 39 31 1 362 5 1 false 0.43635152102464103 0.43635152102464103 2.768478137430898E-53 system_development GO:0048731 12133 2686 31 4 3304 4 2 false 0.4365985378504265 0.4365985378504265 0.0 clathrin-coated_vesicle_membrane GO:0030665 12133 87 31 1 197 1 2 false 0.44162436548220174 0.44162436548220174 3.3450134544276105E-58 regulation_of_defense_response_to_virus_by_virus GO:0050690 12133 27 31 1 61 1 1 false 0.44262295081967723 0.44262295081967723 6.333484478576399E-18 chromosome_organization GO:0051276 12133 689 31 3 2031 7 1 false 0.44298932592677964 0.44298932592677964 0.0 endonucleolytic_cleavage_in_ITS1_to_separate_SSU-rRNA_from_5.8S_rRNA_and_LSU-rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000447 12133 4 31 1 9 1 3 false 0.44444444444444403 0.44444444444444403 0.007936507936507922 leukocyte_differentiation GO:0002521 12133 299 31 1 2177 4 2 false 0.4464487375800614 0.4464487375800614 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 31 2 341 7 4 false 0.44676380325261345 0.44676380325261345 3.257446469032824E-75 microtubule-based_process GO:0007017 12133 378 31 2 7541 30 1 false 0.4480718239920394 0.4480718239920394 0.0 positive_regulation_of_lymphocyte_activation GO:0051251 12133 188 31 1 419 1 3 false 0.44868735083532396 0.44868735083532396 1.71987955515036E-124 negative_regulation_of_protein_modification_process GO:0031400 12133 328 31 2 2431 11 3 false 0.4488852875072332 0.4488852875072332 0.0 positive_regulation_of_T_cell_activation GO:0050870 12133 145 31 1 323 1 3 false 0.4489164086687781 0.4489164086687781 7.1027996669547384E-96 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 31 2 3799 24 1 false 0.44928053414927094 0.44928053414927094 0.0 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 31 1 676 7 2 false 0.4494314745448623 0.4494314745448623 2.737610529852072E-82 endodermal_cell_fate_commitment GO:0001711 12133 14 31 1 31 1 2 false 0.45161290322580533 0.45161290322580533 3.770987549047572E-9 cell_projection_part GO:0044463 12133 491 31 2 9983 31 2 false 0.4550422741308549 0.4550422741308549 0.0 chromatin_assembly GO:0031497 12133 105 31 1 1438 8 3 false 0.4556207223575439 0.4556207223575439 1.4446222867318886E-162 endocytosis GO:0006897 12133 411 31 1 895 1 2 false 0.4592178770950004 0.4592178770950004 2.7872223899360555E-267 nuclear_import GO:0051170 12133 203 31 2 2389 18 3 false 0.46036113929533923 0.46036113929533923 7.452348105569065E-301 activation_of_protein_kinase_activity GO:0032147 12133 247 31 3 417 4 1 false 0.46152187731227684 0.46152187731227684 9.475379918718814E-122 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 31 7 645 7 1 false 0.4623023256502833 0.4623023256502833 7.3138241320053254E-93 embryonic_morphogenesis GO:0048598 12133 406 31 1 2812 4 3 false 0.4642468702323579 0.4642468702323579 0.0 response_to_endoplasmic_reticulum_stress GO:0034976 12133 111 31 1 1124 6 1 false 0.4649165243526429 0.4649165243526429 1.1256089410717349E-156 lyase_activity GO:0016829 12133 230 31 1 4901 13 1 false 0.4650832360606648 0.4650832360606648 0.0 positive_regulation_of_reproductive_process GO:2000243 12133 95 31 1 3700 24 3 false 0.4654015561518178 0.4654015561518178 3.66052287534838E-191 protein_autophosphorylation GO:0046777 12133 173 31 1 1195 4 1 false 0.4654823350686204 0.4654823350686204 7.421869914925723E-214 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 31 4 5183 14 2 false 0.46595524595862914 0.46595524595862914 0.0 negative_regulation_of_catalytic_activity GO:0043086 12133 588 31 2 4970 13 3 false 0.46617641548940214 0.46617641548940214 0.0 macromolecule_glycosylation GO:0043413 12133 137 31 1 2464 11 2 false 0.46772009167577017 0.46772009167577017 5.229995253563594E-229 condensed_chromosome GO:0000793 12133 160 31 1 592 2 1 false 0.46782823432593557 0.46782823432593557 2.5509694139314793E-149 ruffle_membrane GO:0032587 12133 56 31 1 207 2 3 false 0.46883354439284075 0.46883354439284075 5.291580376353652E-52 negative_regulation_of_gene_expression GO:0010629 12133 817 31 6 3906 26 3 false 0.4692725974968723 0.4692725974968723 0.0 mitochondrial_envelope GO:0005740 12133 378 31 1 803 1 2 false 0.4707347447072874 0.4707347447072874 2.632819629334664E-240 response_to_chemical_stimulus GO:0042221 12133 2369 31 7 5200 14 1 false 0.47081823800583333 0.47081823800583333 0.0 positive_regulation_of_cysteine-type_endopeptidase_activity GO:2001056 12133 106 31 1 224 1 3 false 0.4732142857142555 0.4732142857142555 9.593761035739944E-67 positive_regulation_of_protein_import_into_nucleus GO:0042307 12133 61 31 1 222 2 4 false 0.47495006318529487 0.47495006318529487 3.438523611225612E-56 nuclear_part GO:0044428 12133 2767 31 13 6936 31 2 false 0.47559959349335984 0.47559959349335984 0.0 response_to_virus GO:0009615 12133 230 31 2 475 3 1 false 0.47627360477090974 0.47627360477090974 3.548520767075247E-142 protein_glycosylation GO:0006486 12133 137 31 1 2394 11 3 false 0.4777552581698975 0.4777552581698975 3.0420045355065773E-227 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 31 2 362 7 4 false 0.4813975755532108 0.4813975755532108 1.827388630734988E-82 nuclear_DNA-directed_RNA_polymerase_complex GO:0055029 12133 136 31 1 2767 13 2 false 0.48141832848664984 0.48141832848664984 8.223970221232538E-235 positive_regulation_of_metabolic_process GO:0009893 12133 1872 31 7 8366 29 3 false 0.4814396837913071 0.4814396837913071 0.0 T_cell_receptor_signaling_pathway GO:0050852 12133 88 31 3 112 3 1 false 0.4814671814671709 0.4814671814671709 5.828412725788921E-25 protein_domain_specific_binding GO:0019904 12133 486 31 2 6397 21 1 false 0.4814891047414856 0.4814891047414856 0.0 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 31 2 129 3 1 false 0.4824236632484805 0.4824236632484805 2.169508265339551E-38 axon_guidance GO:0007411 12133 295 31 1 611 1 2 false 0.48281505728322394 0.48281505728322394 5.229199602535248E-183 regulation_of_defense_response_to_virus GO:0050688 12133 61 31 1 586 6 5 false 0.48445111944522173 0.48445111944522173 1.8588202781282113E-84 DNA-directed_RNA_polymerase_II,_holoenzyme GO:0016591 12133 124 31 1 809 4 2 false 0.4866857832621907 0.4866857832621907 8.164850025378603E-150 single-organism_carbohydrate_catabolic_process GO:0044724 12133 110 31 1 386 2 2 false 0.48926720947434577 0.48926720947434577 1.4747416896601825E-99 cell_development GO:0048468 12133 1255 31 2 3306 4 4 false 0.4893361733809376 0.4893361733809376 0.0 protein_import GO:0017038 12133 225 31 2 2509 18 2 false 0.4895472805332033 0.4895472805332033 0.0 proteolysis GO:0006508 12133 732 31 6 3431 26 1 false 0.49048326388508484 0.49048326388508484 0.0 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 31 3 129 3 1 false 0.4912676249771082 0.4912676249771082 2.104544859412626E-28 ncRNA_processing GO:0034470 12133 186 31 1 649 2 2 false 0.49136848713125975 0.49136848713125975 4.048832162241149E-168 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 31 2 129 3 1 false 0.49414026735030403 0.49414026735030403 2.1037655906323275E-38 nucleosome_organization GO:0034728 12133 115 31 1 566 3 2 false 0.49476734399503236 0.49476734399503236 1.9962820173380563E-123 negative_regulation_of_NF-kappaB_transcription_factor_activity GO:0032088 12133 51 31 1 103 1 1 false 0.4951456310679525 0.4951456310679525 1.2633713261943138E-30 cation_binding GO:0043169 12133 2758 31 8 4448 12 1 false 0.4958173042837445 0.4958173042837445 0.0 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 31 5 4597 13 2 false 0.49624521049118087 0.49624521049118087 0.0 response_to_interferon-gamma GO:0034341 12133 97 31 1 900 6 2 false 0.49654569197003107 0.49654569197003107 5.665951698458868E-133 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 31 4 2560 6 2 false 0.49657074389148936 0.49657074389148936 0.0 motile_cilium GO:0031514 12133 80 31 1 161 1 1 false 0.49689440993789236 0.49689440993789236 5.465858030116064E-48 regulation_of_response_to_DNA_damage_stimulus GO:2001020 12133 80 31 1 741 6 2 false 0.49739143861842805 0.49739143861842805 1.553661553762129E-109 maturation_of_5.8S_rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000466 12133 6 31 1 12 1 1 false 0.4999999999999995 0.4999999999999995 0.0010822510822510805 coenzyme_binding GO:0050662 12133 136 31 2 192 2 1 false 0.5006544502618249 0.5006544502618249 7.328444571917932E-50 peptidyl-tyrosine_phosphorylation GO:0018108 12133 191 31 1 1195 4 2 false 0.5022084574603523 0.5022084574603523 2.9198379950600046E-227 cysteine-type_peptidase_activity GO:0008234 12133 295 31 1 586 1 1 false 0.5034129692832179 0.5034129692832179 1.2148857586981575E-175 cytokine_metabolic_process GO:0042107 12133 92 31 1 3431 26 1 false 0.5080182327175504 0.5080182327175504 2.347983592216771E-183 programmed_cell_death GO:0012501 12133 1385 31 7 1525 7 1 false 0.5089242854062838 0.5089242854062838 2.142172117700311E-202 response_to_endogenous_stimulus GO:0009719 12133 982 31 3 5200 14 1 false 0.5094432276461115 0.5094432276461115 0.0 regulation_of_DNA_metabolic_process GO:0051052 12133 188 31 1 4316 16 3 false 0.5102428692850086 0.5102428692850086 0.0 cellular_response_to_interferon-gamma GO:0071346 12133 83 31 1 392 3 2 false 0.5112124448441729 0.5112124448441729 2.629901965674187E-87 hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_linear_amides GO:0016811 12133 42 31 1 82 1 1 false 0.5121951219512042 0.5121951219512042 2.4115523257823617E-24 regulation_of_metabolic_process GO:0019222 12133 4469 31 15 9189 30 2 false 0.5124672162718391 0.5124672162718391 0.0 organ_development GO:0048513 12133 1929 31 3 3099 4 2 false 0.5142974774649111 0.5142974774649111 0.0 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 31 3 252 4 2 false 0.5148534033687004 0.5148534033687004 5.925442745937436E-72 dendrite GO:0030425 12133 276 31 1 534 1 1 false 0.516853932584358 0.516853932584358 6.975042602902724E-160 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 31 16 181 16 1 false 0.5171604421585043 0.5171604421585043 8.905994863592909E-13 immune_response-activating_signal_transduction GO:0002757 12133 299 31 4 352 4 2 false 0.5190298812936133 0.5190298812936133 2.8561568566531905E-64 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 31 6 3547 10 1 false 0.5221207198774869 0.5221207198774869 0.0 regulation_of_organelle_organization GO:0033043 12133 519 31 2 2487 8 2 false 0.5221639979132839 0.5221639979132839 0.0 immune_effector_process GO:0002252 12133 445 31 2 1618 6 1 false 0.5246127341851377 0.5246127341851377 0.0 positive_regulation_of_cell_activation GO:0050867 12133 215 31 1 3002 10 3 false 0.5249279367799413 0.5249279367799413 0.0 protein_acylation GO:0043543 12133 155 31 1 2370 11 1 false 0.5255703808460663 0.5255703808460663 6.767829300235778E-248 cell_division GO:0051301 12133 438 31 2 7541 30 1 false 0.5270399697297555 0.5270399697297555 0.0 endomembrane_system GO:0012505 12133 1211 31 4 9983 31 1 false 0.5287932131973085 0.5287932131973085 0.0 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 31 14 8688 30 3 false 0.5303630671316569 0.5303630671316569 0.0 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 31 7 1225 7 2 false 0.5331789180072765 0.5331789180072765 5.928244845001387E-155 cytoplasmic_vesicle GO:0031410 12133 764 31 3 8540 31 3 false 0.533191759346484 0.533191759346484 0.0 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 31 7 7638 29 4 false 0.5334828987721836 0.5334828987721836 0.0 chemokine_production GO:0032602 12133 51 31 1 362 5 1 false 0.534120172670536 0.534120172670536 2.007633269301741E-63 second-messenger-mediated_signaling GO:0019932 12133 257 31 1 1813 5 1 false 0.5347754937298086 0.5347754937298086 1.643E-320 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 31 2 389 7 3 false 0.5354949289154036 0.5354949289154036 8.074632425282073E-93 cell_cycle_process GO:0022402 12133 953 31 4 7541 30 2 false 0.5360187545538817 0.5360187545538817 0.0 NAD+_ADP-ribosyltransferase_activity GO:0003950 12133 22 31 1 41 1 1 false 0.5365853658536638 0.5365853658536638 4.087260223157657E-12 cellular_component_organization GO:0016043 12133 3745 31 25 3839 25 1 false 0.537015980525344 0.537015980525344 4.153510440731863E-191 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 31 1 374 1 2 false 0.5401069518716204 0.5401069518716204 2.0954491420584897E-111 protein_tyrosine_kinase_activity GO:0004713 12133 180 31 1 1014 4 1 false 0.5429577662118797 0.5429577662118797 3.660578992202259E-205 regulation_of_cell_activation GO:0050865 12133 303 31 1 6351 16 2 false 0.5430139713290764 0.5430139713290764 0.0 positive_regulation_of_viral_transcription GO:0050434 12133 50 31 1 1309 20 7 false 0.5437608476656812 0.5437608476656812 1.1161947571885395E-91 regulation_of_Wnt_receptor_signaling_pathway GO:0030111 12133 156 31 1 1668 8 2 false 0.5449161703858014 0.5449161703858014 2.89270864030114E-224 nuclease_activity GO:0004518 12133 197 31 1 853 3 2 false 0.5456351761429903 0.5456351761429903 1.9441890942275812E-199 taxis GO:0042330 12133 488 31 1 1496 2 2 false 0.5461449036903218 0.5461449036903218 0.0 regulation_of_nucleocytoplasmic_transport GO:0046822 12133 147 31 1 450 2 2 false 0.5471121009650309 0.5471121009650309 8.40005869125793E-123 cell_leading_edge GO:0031252 12133 252 31 1 9983 31 1 false 0.5478698209184669 0.5478698209184669 0.0 regulation_of_T_cell_activation GO:0050863 12133 186 31 1 339 1 2 false 0.548672566371674 0.548672566371674 1.0254523445533855E-100 transcription_factor_complex GO:0005667 12133 266 31 1 3138 9 2 false 0.5498874352532566 0.5498874352532566 0.0 regulation_of_endopeptidase_activity GO:0052548 12133 264 31 1 480 1 2 false 0.550000000000017 0.550000000000017 9.691263405564588E-143 intracellular_organelle_lumen GO:0070013 12133 2919 31 15 5320 27 2 false 0.550836852824745 0.550836852824745 0.0 nucleoplasm_part GO:0044451 12133 805 31 4 2767 13 2 false 0.5510626233444677 0.5510626233444677 0.0 transcription_coactivator_activity GO:0003713 12133 264 31 1 478 1 2 false 0.5523012552300889 0.5523012552300889 4.798051856605128E-142 regulation_of_chemokine_production GO:0032642 12133 48 31 1 325 5 2 false 0.5526546192614696 0.5526546192614696 1.2887394790079774E-58 organelle_lumen GO:0043233 12133 2968 31 15 5401 27 2 false 0.5543631782398142 0.5543631782398142 0.0 protein-DNA_complex GO:0032993 12133 110 31 1 3462 25 1 false 0.555181639021372 0.555181639021372 4.3156565695482125E-211 single-organism_carbohydrate_metabolic_process GO:0044723 12133 385 31 2 515 2 1 false 0.5584979789202698 0.5584979789202698 1.0653300741927565E-125 regulation_of_peptidyl-tyrosine_phosphorylation GO:0050730 12133 150 31 1 812 4 2 false 0.5589595982083191 0.5589595982083191 5.072476466269739E-168 regulation_of_canonical_Wnt_receptor_signaling_pathway GO:0060828 12133 108 31 1 193 1 2 false 0.5595854922279625 0.5595854922279625 5.446526497036233E-57 peptidase_activity GO:0008233 12133 614 31 1 2556 3 1 false 0.5615663854022671 0.5615663854022671 0.0 carbohydrate_biosynthetic_process GO:0016051 12133 132 31 1 4212 26 2 false 0.5641087124351576 0.5641087124351576 3.288354819591378E-254 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 31 2 129 3 1 false 0.5642996932796249 0.5642996932796249 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 31 2 129 3 1 false 0.5642996932796249 0.5642996932796249 3.3394798770258706E-38 regulation_of_lymphocyte_activation GO:0051249 12133 245 31 1 434 1 2 false 0.5645161290321338 0.5645161290321338 2.1869753110099554E-128 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 31 1 308 1 2 false 0.5649350649350205 0.5649350649350205 5.66231040699253E-91 positive_regulation_of_peptidyl-tyrosine_phosphorylation GO:0050731 12133 113 31 1 602 4 3 false 0.5656449496040904 0.5656449496040904 1.3602790060815964E-125 Wnt_receptor_signaling_pathway GO:0016055 12133 260 31 1 1975 6 1 false 0.571766054126764 0.571766054126764 0.0 cell_projection_morphogenesis GO:0048858 12133 541 31 1 946 1 3 false 0.5718816067655231 0.5718816067655231 1.1683643564827775E-279 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 31 2 587 4 2 false 0.5722819993743713 0.5722819993743713 2.854325455984618E-173 cellular_protein_complex_disassembly GO:0043624 12133 149 31 16 154 16 1 false 0.5733940510516966 0.5733940510516966 1.4793035521715585E-9 regulation_of_stress-activated_protein_kinase_signaling_cascade GO:0070302 12133 147 31 1 765 4 3 false 0.5748960268452475 0.5748960268452475 7.281108340064304E-162 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 31 2 129 3 1 false 0.5759161554660286 0.5759161554660286 4.0186961232005657E-38 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 31 4 2877 12 6 false 0.5789740548427159 0.5789740548427159 0.0 acid-amino_acid_ligase_activity GO:0016881 12133 351 31 7 379 7 1 false 0.5817449121489696 0.5817449121489696 5.324332733169013E-43 posttranscriptional_gene_silencing_by_RNA GO:0035194 12133 28 31 1 48 1 2 false 0.5833333333333295 0.5833333333333295 5.975257849517426E-14 peptidyl-amino_acid_modification GO:0018193 12133 623 31 3 2370 11 1 false 0.5843296740665151 0.5843296740665151 0.0 canonical_Wnt_receptor_signaling_pathway GO:0060070 12133 152 31 1 260 1 1 false 0.5846153846154019 0.5846153846154019 4.5351475920205146E-76 cell_cycle_phase_transition GO:0044770 12133 415 31 2 953 4 1 false 0.5853115834898164 0.5853115834898164 1.4433288987581492E-282 nucleolus GO:0005730 12133 1357 31 8 4208 25 3 false 0.5855363338543843 0.5855363338543843 0.0 regulation_of_anatomical_structure_morphogenesis GO:0022603 12133 528 31 1 2074 3 2 false 0.586012275077466 0.586012275077466 0.0 endoplasmic_reticulum_membrane GO:0005789 12133 487 31 1 3544 6 4 false 0.5883603543390443 0.5883603543390443 0.0 transcription-coupled_nucleotide-excision_repair GO:0006283 12133 46 31 1 78 1 1 false 0.589743589743583 0.589743589743583 1.2785885050503116E-22 clathrin_coat GO:0030118 12133 39 31 1 66 1 1 false 0.5909090909090968 0.5909090909090968 4.080314872103393E-19 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 31 1 1376 7 3 false 0.591893193522645 0.591893193522645 2.059495184181185E-218 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 31 5 5558 25 3 false 0.5923141862954531 0.5923141862954531 0.0 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 31 1 3447 4 2 false 0.5927132874822924 0.5927132874822924 0.0 DNA-dependent_transcription,_elongation GO:0006354 12133 105 31 1 2751 23 2 false 0.5929114142573185 0.5929114142573185 5.761796228239027E-193 neuron_apoptotic_process GO:0051402 12133 158 31 2 281 3 2 false 0.5932633069299459 0.5932633069299459 4.7762266380223384E-83 glycoprotein_metabolic_process GO:0009100 12133 205 31 1 6720 29 3 false 0.593574205380517 0.593574205380517 0.0 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 31 2 136 2 2 false 0.5947712418300675 0.5947712418300675 2.4301849830786213E-31 glycosylation GO:0070085 12133 140 31 1 385 2 1 false 0.5956439393939456 0.5956439393939456 5.964220032896676E-109 cell_projection GO:0042995 12133 976 31 3 9983 31 1 false 0.5957940379067037 0.5957940379067037 0.0 steroid_hormone_receptor_binding GO:0035258 12133 62 31 1 104 1 1 false 0.5961538461538246 0.5961538461538246 4.2931773052216616E-30 regulation_of_molecular_function GO:0065009 12133 2079 31 6 10494 31 2 false 0.5970512999652584 0.5970512999652584 0.0 regulation_of_cytoskeleton_organization GO:0051493 12133 250 31 1 955 3 2 false 0.5981421519852418 0.5981421519852418 1.2229840665192896E-237 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 31 2 90 2 3 false 0.6029962546816539 0.6029962546816539 1.9615250672171495E-20 cell_cycle GO:0007049 12133 1295 31 5 7541 30 1 false 0.6047334153861934 0.6047334153861934 0.0 carbohydrate_metabolic_process GO:0005975 12133 515 31 2 7453 29 2 false 0.6052653169580842 0.6052653169580842 0.0 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 31 1 766 1 2 false 0.6070496083553625 0.6070496083553625 4.217322594612318E-222 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 31 3 1730 8 2 false 0.608548951900602 0.608548951900602 0.0 gamete_generation GO:0007276 12133 355 31 1 581 1 3 false 0.6110154905334247 0.6110154905334247 6.960007714092178E-168 response_to_bacterium GO:0009617 12133 273 31 2 475 3 1 false 0.6115022402260493 0.6115022402260493 5.69705453618735E-140 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 31 2 1256 21 1 false 0.6115252352039517 0.6115252352039517 3.1457660386089413E-171 regulation_of_multicellular_organismal_development GO:2000026 12133 953 31 2 3481 7 3 false 0.6125333210153256 0.6125333210153256 0.0 spindle_organization GO:0007051 12133 78 31 1 1776 21 3 false 0.612732069484281 0.612732069484281 2.2015050227101385E-138 androgen_receptor_binding GO:0050681 12133 38 31 1 62 1 1 false 0.6129032258064553 0.6129032258064553 1.0311688046013243E-17 clathrin_adaptor_complex GO:0030131 12133 27 31 1 44 1 2 false 0.6136363636363645 0.6136363636363645 1.4569745267658192E-12 cellular_membrane_organization GO:0016044 12133 784 31 3 7541 30 2 false 0.6166237967047147 0.6166237967047147 0.0 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 31 1 768 1 1 false 0.6210937499998362 0.6210937499998362 1.6461815804374103E-220 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 31 2 129 3 1 false 0.6219528245742534 0.6219528245742534 1.1512773005265922E-37 response_to_immune_response_of_other_organism_involved_in_symbiotic_interaction GO:0052564 12133 5 31 1 8 1 1 false 0.6249999999999999 0.6249999999999999 0.01785714285714285 response_to_host_immune_response GO:0052572 12133 5 31 1 8 1 2 false 0.6249999999999999 0.6249999999999999 0.01785714285714285 cellular_response_to_unfolded_protein GO:0034620 12133 82 31 1 131 1 2 false 0.6259541984732812 0.6259541984732812 3.4132414427749756E-37 in_utero_embryonic_development GO:0001701 12133 295 31 1 471 1 1 false 0.6263269639064891 0.6263269639064891 1.719393530200133E-134 kinase_binding GO:0019900 12133 384 31 2 1005 5 1 false 0.6318876615800691 0.6318876615800691 2.0091697589355545E-289 coated_vesicle GO:0030135 12133 202 31 1 712 3 1 false 0.6331033658454712 0.6331033658454712 1.1363731817938802E-183 negative_regulation_of_cell_death GO:0060548 12133 567 31 2 3054 11 3 false 0.6340867619179767 0.6340867619179767 0.0 organ_morphogenesis GO:0009887 12133 649 31 1 2908 4 3 false 0.6360601244355812 0.6360601244355812 0.0 perinuclear_region_of_cytoplasm GO:0048471 12133 416 31 2 5117 26 1 false 0.63664658693855 0.63664658693855 0.0 ribosome_biogenesis GO:0042254 12133 144 31 2 243 3 1 false 0.6378585299747147 0.6378585299747147 8.984879194471426E-71 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 31 3 1079 7 3 false 0.6384691899267152 0.6384691899267152 5.98264E-319 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 31 2 217 4 1 false 0.6427939873263465 0.6427939873263465 1.2933579260360868E-64 regulation_of_cell_differentiation GO:0045595 12133 872 31 2 6612 16 3 false 0.6433446502853447 0.6433446502853447 0.0 organelle_membrane GO:0031090 12133 1619 31 5 9319 31 3 false 0.6461843061027142 0.6461843061027142 0.0 embryo_development GO:0009790 12133 768 31 1 3347 4 3 false 0.6476692952336565 0.6476692952336565 0.0 maintenance_of_location GO:0051235 12133 184 31 1 4158 23 2 false 0.6478970722989327 0.6478970722989327 0.0 protein_heterodimerization_activity GO:0046982 12133 317 31 1 779 2 1 false 0.6485805082650417 0.6485805082650417 8.49214053182804E-228 intracellular_signal_transduction GO:0035556 12133 1813 31 5 3547 10 1 false 0.6503328683232849 0.6503328683232849 0.0 protein_serine/threonine_kinase_activity GO:0004674 12133 709 31 3 1014 4 1 false 0.6503933932458723 0.6503933932458723 1.8231541307779663E-268 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 31 5 5151 25 4 false 0.6507826061077702 0.6507826061077702 0.0 chromatin_binding GO:0003682 12133 309 31 1 8962 30 1 false 0.6515836941228086 0.6515836941228086 0.0 kinase_activity GO:0016301 12133 1174 31 4 1546 5 2 false 0.6526159370466273 0.6526159370466273 0.0 protein_binding GO:0005515 12133 6397 31 21 8962 30 1 false 0.6531400121668117 0.6531400121668117 0.0 anatomical_structure_development GO:0048856 12133 3099 31 4 3447 4 1 false 0.6531850279989884 0.6531850279989884 0.0 peptidyl-lysine_modification GO:0018205 12133 185 31 1 623 3 1 false 0.6532056564572516 0.6532056564572516 7.634244791194444E-164 phosphatase_activity GO:0016791 12133 306 31 1 465 1 2 false 0.6580645161290675 0.6580645161290675 4.9712656169712896E-129 carbohydrate_catabolic_process GO:0016052 12133 112 31 1 2356 22 2 false 0.659193525882628 0.659193525882628 5.972721726257644E-195 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 31 2 86 2 2 false 0.6607387140902996 0.6607387140902996 1.0344828145516245E-17 zinc_ion_binding GO:0008270 12133 1314 31 4 1457 4 1 false 0.6612235173177182 0.6612235173177182 2.194714234876188E-202 anatomical_structure_morphogenesis GO:0009653 12133 1664 31 2 3447 4 2 false 0.661272382174249 0.661272382174249 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 31 2 81 2 2 false 0.6620370370370483 0.6620370370370483 1.2278945146862784E-16 synapse GO:0045202 12133 368 31 1 10701 31 1 false 0.662564615577691 0.662564615577691 0.0 formation_of_translation_preinitiation_complex GO:0001731 12133 15 31 1 249 17 2 false 0.664768846623158 0.664768846623158 2.2924908925658003E-24 peptidyl-tyrosine_modification GO:0018212 12133 191 31 1 623 3 1 false 0.6672949131334875 0.6672949131334875 5.019013158282893E-166 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 31 1 1379 2 2 false 0.6678194901554977 0.6678194901554977 0.0 phosphoprotein_phosphatase_activity GO:0004721 12133 206 31 1 306 1 1 false 0.6732026143789835 0.6732026143789835 2.1851087098036358E-83 cardiovascular_system_development GO:0072358 12133 655 31 1 2686 4 2 false 0.6733350968058435 0.6733350968058435 0.0 circulatory_system_development GO:0072359 12133 655 31 1 2686 4 1 false 0.6733350968058435 0.6733350968058435 0.0 toll-like_receptor_signaling_pathway GO:0002224 12133 129 31 3 147 3 1 false 0.6738530650805338 0.6738530650805338 1.843896992838607E-23 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 31 1 307 1 1 false 0.6742671009771501 0.6742671009771501 1.4733469150792184E-83 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 31 6 5303 28 3 false 0.6743462018850541 0.6743462018850541 0.0 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 31 2 129 3 1 false 0.6781038271379052 0.6781038271379052 8.751505837166389E-37 regulation_of_stress-activated_MAPK_cascade GO:0032872 12133 146 31 1 463 3 3 false 0.680012504935372 0.680012504935372 1.1657182873431035E-124 cell_part_morphogenesis GO:0032990 12133 551 31 1 810 1 1 false 0.6802469135803918 0.6802469135803918 1.1709501739830369E-219 covalent_chromatin_modification GO:0016569 12133 312 31 1 458 1 1 false 0.6812227074236363 0.6812227074236363 7.826311589520491E-124 mitochondrial_matrix GO:0005759 12133 236 31 1 3218 15 2 false 0.6818008649625451 0.6818008649625451 0.0 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 31 2 185 2 1 false 0.6831962397181021 0.6831962397181021 1.2806047113744547E-36 macromolecule_modification GO:0043412 12133 2461 31 11 6052 29 1 false 0.6842406156556943 0.6842406156556943 0.0 interaction_with_host GO:0051701 12133 387 31 5 417 5 2 false 0.6871651445785305 0.6871651445785305 1.9217516081652173E-46 protein_ubiquitination GO:0016567 12133 548 31 7 578 7 1 false 0.6872243240342412 0.6872243240342412 7.913703273197485E-51 rRNA_processing GO:0006364 12133 102 31 1 231 2 3 false 0.6892151326932874 0.6892151326932874 2.6685808966337758E-68 regulation_of_growth GO:0040008 12133 447 31 1 6651 17 2 false 0.694014136325315 0.694014136325315 0.0 endoplasmic_reticulum_unfolded_protein_response GO:0030968 12133 82 31 1 118 1 3 false 0.6949152542372992 0.6949152542372992 3.7748187458517594E-31 regulation_of_immune_effector_process GO:0002697 12133 188 31 1 891 5 2 false 0.6951546227820826 0.6951546227820826 1.2449327492079068E-198 membrane-bounded_vesicle GO:0031988 12133 762 31 4 834 4 1 false 0.6964013336847047 0.6964013336847047 6.820230733401612E-106 nucleotide-excision_repair GO:0006289 12133 78 31 1 368 5 1 false 0.6983196370800016 0.6983196370800016 5.504322769590107E-82 regulation_of_biosynthetic_process GO:0009889 12133 3012 31 14 5483 27 2 false 0.6984597999326198 0.6984597999326198 0.0 sequence-specific_DNA_binding_RNA_polymerase_II_transcription_factor_activity GO:0000981 12133 226 31 1 1815 9 4 false 0.6987020807123276 0.6987020807123276 1.998611403782172E-295 receptor_activity GO:0004872 12133 790 31 2 10257 31 1 false 0.701449505381248 0.701449505381248 0.0 coated_vesicle_membrane GO:0030662 12133 122 31 1 368 3 2 false 0.7024937803577667 0.7024937803577667 6.74679218492705E-101 protein_homodimerization_activity GO:0042803 12133 471 31 1 1035 2 2 false 0.7032938076413167 0.7032938076413167 7.159384282986134E-309 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 31 6 4582 26 3 false 0.7054080439264838 0.7054080439264838 0.0 microtubule_binding GO:0008017 12133 106 31 1 150 1 1 false 0.706666666666671 0.706666666666671 5.3333104558304893E-39 neuron_projection_development GO:0031175 12133 575 31 1 812 1 2 false 0.7081280788176632 0.7081280788176632 3.771933680434825E-212 modification-dependent_protein_catabolic_process GO:0019941 12133 378 31 6 400 6 2 false 0.7106143107441765 0.7106143107441765 1.150456419433401E-36 nuclear_chromosome_part GO:0044454 12133 244 31 1 2878 14 3 false 0.7115480410252923 0.7115480410252923 0.0 T_cell_activation GO:0042110 12133 288 31 1 403 1 1 false 0.7146401985111832 0.7146401985111832 5.060432780788644E-104 cell_surface GO:0009986 12133 396 31 1 9983 31 1 false 0.7154005727700524 0.7154005727700524 0.0 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 31 2 220 6 1 false 0.7173795484161145 0.7173795484161145 2.4407604211478482E-62 cellular_component_biogenesis GO:0044085 12133 1525 31 9 3839 25 1 false 0.7176907124792116 0.7176907124792116 0.0 glycoprotein_biosynthetic_process GO:0009101 12133 174 31 1 3677 26 3 false 0.717711356021129 0.717711356021129 1.653253662203381E-303 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 31 6 4456 26 4 false 0.7184558022979666 0.7184558022979666 0.0 organelle_organization GO:0006996 12133 2031 31 7 7663 30 2 false 0.718684274637692 0.718684274637692 0.0 small_conjugating_protein_ligase_activity GO:0019787 12133 335 31 7 351 7 1 false 0.7192948026797681 0.7192948026797681 5.577217121688537E-28 transition_metal_ion_binding GO:0046914 12133 1457 31 4 2699 8 1 false 0.7201433396411623 0.7201433396411623 0.0 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 31 5 1779 7 1 false 0.7205983190045485 0.7205983190045485 0.0 positive_regulation_of_leukocyte_activation GO:0002696 12133 206 31 1 756 4 4 false 0.7207019847263902 0.7207019847263902 1.5163059036704027E-191 negative_regulation_of_developmental_process GO:0051093 12133 463 31 1 4566 12 3 false 0.7232563467563878 0.7232563467563878 0.0 transport GO:0006810 12133 2783 31 18 2833 18 1 false 0.7250637983225824 0.7250637983225824 1.147202604491021E-108 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 31 15 6638 29 2 false 0.7253442702420194 0.7253442702420194 0.0 protein-DNA_complex_subunit_organization GO:0071824 12133 147 31 2 1256 21 1 false 0.7253532128317237 0.7253532128317237 3.54580927907897E-196 positive_regulation_of_hydrolase_activity GO:0051345 12133 562 31 1 2891 6 3 false 0.726986662990926 0.726986662990926 0.0 regulation_of_primary_metabolic_process GO:0080090 12133 3921 31 14 7507 29 2 false 0.7304187817724286 0.7304187817724286 0.0 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 31 11 3120 14 4 false 0.7321760028685407 0.7321760028685407 0.0 nucleotide_binding GO:0000166 12133 1997 31 6 2103 6 2 false 0.7329393431774106 0.7329393431774106 1.0169073992212018E-181 regulation_of_protein_metabolic_process GO:0051246 12133 1388 31 6 5563 28 3 false 0.7348781322025074 0.7348781322025074 0.0 maintenance_of_protein_location GO:0045185 12133 100 31 1 1490 19 2 false 0.7350735545965356 0.7350735545965356 1.3409119998512189E-158 organelle_fission GO:0048285 12133 351 31 1 2031 7 1 false 0.7356038663658698 0.7356038663658698 0.0 regulation_of_protein_import_into_nucleus GO:0042306 12133 121 31 1 248 2 4 false 0.7387684471724912 0.7387684471724912 4.6955049394038436E-74 small_molecule_binding GO:0036094 12133 2102 31 6 8962 30 1 false 0.7388494661835228 0.7388494661835228 0.0 cellular_component_assembly GO:0022607 12133 1392 31 8 3836 25 2 false 0.7400444147225885 0.7400444147225885 0.0 oxidoreductase_activity GO:0016491 12133 491 31 1 4974 13 2 false 0.7414936454418086 0.7414936454418086 0.0 negative_regulation_of_cell_differentiation GO:0045596 12133 381 31 1 3552 12 4 false 0.7443136084964423 0.7443136084964423 0.0 protein_dimerization_activity GO:0046983 12133 779 31 2 6397 21 1 false 0.7445700874148262 0.7445700874148262 0.0 neuron_projection_morphogenesis GO:0048812 12133 475 31 1 637 1 2 false 0.7456828885398858 0.7456828885398858 3.7535814082411355E-156 chromosomal_part GO:0044427 12133 512 31 2 5337 27 2 false 0.74691842924625 0.74691842924625 0.0 neuron_development GO:0048666 12133 654 31 1 1313 2 2 false 0.7482828841045447 0.7482828841045447 0.0 regulation_of_protein_modification_process GO:0031399 12133 1001 31 4 2566 12 2 false 0.7535564911894704 0.7535564911894704 0.0 regionalization GO:0003002 12133 246 31 1 326 1 1 false 0.754601226993791 0.754601226993791 2.501957085662731E-78 cytokine_biosynthetic_process GO:0042089 12133 89 31 1 364 5 2 false 0.7560741558003254 0.7560741558003254 2.424583571152321E-87 response_to_stimulus GO:0050896 12133 5200 31 14 10446 31 1 false 0.7560818192569747 0.7560818192569747 0.0 nuclear_chromosome GO:0000228 12133 278 31 1 2899 14 3 false 0.7569964729551473 0.7569964729551473 0.0 oxidoreductase_activity,_acting_on_the_aldehyde_or_oxo_group_of_donors,_NAD_or_NADP_as_acceptor GO:0016620 12133 22 31 1 29 1 1 false 0.7586206896551748 0.7586206896551748 6.407052883814491E-7 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 31 7 6129 29 3 false 0.7590560169094219 0.7590560169094219 0.0 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 31 6 3972 26 4 false 0.7599544532538598 0.7599544532538598 0.0 RNA_splicing GO:0008380 12133 307 31 1 601 2 1 false 0.7611148086524555 0.7611148086524555 4.262015823312228E-180 response_to_organic_substance GO:0010033 12133 1783 31 5 2369 7 1 false 0.762092322366978 0.762092322366978 0.0 male_gamete_generation GO:0048232 12133 271 31 1 355 1 1 false 0.7633802816901516 0.7633802816901516 8.83354474391846E-84 catalytic_activity GO:0003824 12133 4901 31 13 10478 31 2 false 0.7636416563565461 0.7636416563565461 0.0 calcium_ion_binding GO:0005509 12133 447 31 1 2699 8 1 false 0.7655620596604489 0.7655620596604489 0.0 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 31 5 3847 24 4 false 0.7695737995136476 0.7695737995136476 0.0 positive_regulation_of_cell_death GO:0010942 12133 383 31 1 3330 12 3 false 0.7697978338313749 0.7697978338313749 0.0 signaling GO:0023052 12133 3878 31 10 10446 31 1 false 0.7702268143445707 0.7702268143445707 0.0 cytoskeleton_organization GO:0007010 12133 719 31 2 2031 7 1 false 0.7734430569948572 0.7734430569948572 0.0 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 31 2 185 2 1 false 0.7757344300823621 0.7757344300823621 5.464989090238489E-29 generation_of_precursor_metabolites_and_energy GO:0006091 12133 364 31 1 7256 29 1 false 0.7758674325683126 0.7758674325683126 0.0 positive_regulation_of_developmental_process GO:0051094 12133 603 31 1 4731 11 3 false 0.7771998612949302 0.7771998612949302 0.0 protein_binding_transcription_factor_activity GO:0000988 12133 488 31 1 10311 31 3 false 0.7780428684688545 0.7780428684688545 0.0 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 31 7 2849 20 1 false 0.7797558597442149 0.7797558597442149 0.0 early_endosome_membrane GO:0031901 12133 72 31 1 322 6 2 false 0.7839266358910794 0.7839266358910794 9.050748521775936E-74 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 31 2 71 2 3 false 0.785915492957749 0.785915492957749 9.399268641403064E-11 plasma_membrane_part GO:0044459 12133 1329 31 3 10213 31 3 false 0.7874147175912806 0.7874147175912806 0.0 nuclear_outer_membrane-endoplasmic_reticulum_membrane_network GO:0042175 12133 499 31 1 10252 31 4 false 0.7875735778371213 0.7875735778371213 0.0 protein_kinase_binding GO:0019901 12133 341 31 2 384 2 1 false 0.7883213664057611 0.7883213664057611 5.20098898434574E-58 mitotic_cell_cycle GO:0000278 12133 625 31 2 1295 5 1 false 0.7905088524567245 0.7905088524567245 0.0 basal_transcription_machinery_binding GO:0001098 12133 464 31 1 6397 21 1 false 0.7948174235993761 0.7948174235993761 0.0 phosphoric_ester_hydrolase_activity GO:0042578 12133 446 31 1 814 2 1 false 0.7959207110498319 0.7959207110498319 1.3758870371320904E-242 transmembrane_transport GO:0055085 12133 728 31 2 7606 30 2 false 0.7964703891798267 0.7964703891798267 0.0 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 31 4 803 6 1 false 0.7979957534984075 0.7979957534984075 1.0286714317927864E-202 chemotaxis GO:0006935 12133 488 31 1 2369 7 2 false 0.8014978131418949 0.8014978131418949 0.0 regulation_of_biological_quality GO:0065008 12133 2082 31 4 6908 17 1 false 0.8018582652100181 0.8018582652100181 0.0 activation_of_cysteine-type_endopeptidase_activity GO:0097202 12133 85 31 1 106 1 1 false 0.801886792452837 0.801886792452837 1.25561322378657E-22 gene_silencing_by_RNA GO:0031047 12133 48 31 1 87 2 1 false 0.8019246190858309 0.8019246190858309 1.2013602639031232E-25 clathrin-coated_vesicle GO:0030136 12133 162 31 1 202 1 1 false 0.8019801980198291 0.8019801980198291 3.1333299685548734E-43 endopeptidase_activity GO:0004175 12133 470 31 1 586 1 1 false 0.802047781569667 0.802047781569667 5.73935751356398E-126 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 31 14 4972 26 3 false 0.8041009786973432 0.8041009786973432 0.0 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 31 3 312 4 1 false 0.8072229948349612 0.8072229948349612 8.216510305576978E-69 chromatin GO:0000785 12133 287 31 1 512 2 1 false 0.8073630136987906 0.8073630136987906 9.050120143931621E-152 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 31 4 1304 5 1 false 0.8074511462633006 0.8074511462633006 1.004636319027547E-252 monosaccharide_metabolic_process GO:0005996 12133 217 31 1 385 2 1 false 0.8102272727273129 0.8102272727273129 7.061110236111427E-114 RNA_localization GO:0006403 12133 131 31 1 1642 20 1 false 0.8123134875483622 0.8123134875483622 1.0675246049472868E-197 mitosis GO:0007067 12133 326 31 1 953 4 2 false 0.813244883125815 0.813244883125815 4.8424843971573165E-265 negative_regulation_of_cell_proliferation GO:0008285 12133 455 31 1 2949 10 3 false 0.813359927175908 0.813359927175908 0.0 regulation_of_developmental_process GO:0050793 12133 1233 31 2 7209 17 2 false 0.8145374573272264 0.8145374573272264 0.0 cell_differentiation GO:0030154 12133 2154 31 4 2267 4 1 false 0.8149225803350817 0.8149225803350817 2.602261335719434E-194 DNA_conformation_change GO:0071103 12133 194 31 1 791 6 1 false 0.8163054261914755 0.8163054261914755 1.3022788504353465E-190 regulation_of_leukocyte_activation GO:0002694 12133 278 31 1 948 5 3 false 0.8244405585363674 0.8244405585363674 2.7935655578419027E-248 receptor_binding GO:0005102 12133 918 31 2 6397 21 1 false 0.8257938050889124 0.8257938050889124 0.0 positive_regulation_of_intracellular_transport GO:0032388 12133 126 31 1 1370 18 3 false 0.8258835891913148 0.8258835891913148 5.304932497681123E-182 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 31 2 1399 7 3 false 0.8269894738086447 0.8269894738086447 0.0 small_ribosomal_subunit GO:0015935 12133 60 31 6 132 16 1 false 0.828417640548852 0.828417640548852 4.556510204279982E-39 negative_regulation_of_apoptotic_process GO:0043066 12133 537 31 2 1377 7 3 false 0.8285663730561423 0.8285663730561423 0.0 RNA_polymerase_II_regulatory_region_DNA_binding GO:0001012 12133 260 31 1 1169 7 1 false 0.8289966589606199 0.8289966589606199 3.195774442512401E-268 anion_binding GO:0043168 12133 2280 31 5 4448 12 1 false 0.8299021217279657 0.8299021217279657 0.0 locomotion GO:0040011 12133 1045 31 2 10446 31 1 false 0.8310226397292364 0.8310226397292364 0.0 protein_phosphorylation GO:0006468 12133 1195 31 4 2577 11 2 false 0.833488095378512 0.833488095378512 0.0 plasma_membrane GO:0005886 12133 2594 31 6 10252 31 3 false 0.8335982679358676 0.8335982679358676 0.0 mRNA_binding GO:0003729 12133 91 31 1 763 14 1 false 0.833764963986531 0.833764963986531 1.7788235024198917E-120 extracellular_matrix_structural_constituent GO:0005201 12133 52 31 1 526 17 1 false 0.8344699471282674 0.8344699471282674 3.530187938425485E-73 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 31 2 165 2 2 false 0.8370288248337823 0.8370288248337823 1.3866478491946915E-20 tissue_development GO:0009888 12133 1132 31 1 3099 4 1 false 0.8378762037379238 0.8378762037379238 0.0 RNA_polymerase_II_regulatory_region_sequence-specific_DNA_binding GO:0000977 12133 257 31 1 1123 7 2 false 0.83873278181286 0.83873278181286 1.6391430287111727E-261 response_to_decreased_oxygen_levels GO:0036293 12133 202 31 3 214 3 1 false 0.8403267426814965 0.8403267426814965 7.108512362452622E-20 metal_ion_binding GO:0046872 12133 2699 31 8 2758 8 1 false 0.8409543520491872 0.8409543520491872 2.6200760259069314E-123 maintenance_of_protein_location_in_cell GO:0032507 12133 90 31 1 933 18 3 false 0.841758032209377 0.841758032209377 6.448935914517526E-128 small_molecule_metabolic_process GO:0044281 12133 2423 31 1 2877 1 1 false 0.842196732708071 0.842196732708071 0.0 regulation_of_hydrolase_activity GO:0051336 12133 821 31 1 3094 6 2 false 0.8430673917455678 0.8430673917455678 0.0 protein_processing GO:0016485 12133 113 31 2 123 2 1 false 0.8433959749433164 0.8433959749433164 6.665856545071852E-15 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 31 1 971 21 2 false 0.8463474126805075 0.8463474126805075 1.7939571902377886E-121 protein_stabilization GO:0050821 12133 60 31 1 99 2 1 false 0.8472479901050973 0.8472479901050973 1.818679918792965E-28 endoplasmic_reticulum GO:0005783 12133 854 31 2 8213 31 2 false 0.8476382569725044 0.8476382569725044 0.0 ncRNA_metabolic_process GO:0034660 12133 258 31 1 3294 23 1 false 0.8477876862193389 0.8477876862193389 0.0 interphase GO:0051325 12133 233 31 2 253 2 1 false 0.8478574565529252 0.8478574565529252 4.555981744751407E-30 lymphocyte_activation GO:0046649 12133 403 31 1 475 1 1 false 0.8484210526316471 0.8484210526316471 3.3805466364584557E-87 androgen_receptor_signaling_pathway GO:0030521 12133 62 31 1 102 2 1 false 0.8485730926033468 0.8485730926033468 2.6706454874295595E-29 neuron_differentiation GO:0030182 12133 812 31 1 2154 4 2 false 0.8495839211866583 0.8495839211866583 0.0 nucleosome_assembly GO:0006334 12133 94 31 1 154 2 3 false 0.8497580850520956 0.8497580850520956 2.9283606569953104E-44 transmembrane_signaling_receptor_activity GO:0004888 12133 539 31 1 633 1 1 false 0.8515007898894003 0.8515007898894003 7.293829448224349E-115 cytoskeletal_protein_binding GO:0008092 12133 556 31 1 6397 21 1 false 0.8523043135710432 0.8523043135710432 0.0 nuclear_hormone_receptor_binding GO:0035257 12133 104 31 1 122 1 1 false 0.8524590163934733 0.8524590163934733 6.677251530520905E-22 leukocyte_activation GO:0045321 12133 475 31 1 1729 6 2 false 0.8549277067806478 0.8549277067806478 0.0 regulation_of_cellular_component_organization GO:0051128 12133 1152 31 3 7336 29 2 false 0.8559525271769434 0.8559525271769434 0.0 neurogenesis GO:0022008 12133 940 31 1 2425 4 2 false 0.8595965440312778 0.8595965440312778 0.0 neuron_part GO:0097458 12133 612 31 1 9983 31 1 false 0.8597357589071315 0.8597357589071315 0.0 growth GO:0040007 12133 646 31 1 10446 31 1 false 0.8621899954434018 0.8621899954434018 0.0 JNK_cascade GO:0007254 12133 159 31 2 207 3 1 false 0.8650262365857009 0.8650262365857009 3.1556682987155503E-48 cell_cycle_checkpoint GO:0000075 12133 202 31 2 217 2 1 false 0.8662314388120638 0.8662314388120638 1.925703524045096E-23 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 31 4 3771 28 4 false 0.8673860380227871 0.8673860380227871 0.0 axonogenesis GO:0007409 12133 421 31 1 483 1 2 false 0.8716356107660534 0.8716356107660534 7.423880338325494E-80 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 31 4 4044 28 3 false 0.8718137316948759 0.8718137316948759 0.0 envelope GO:0031975 12133 641 31 1 9983 31 1 false 0.8726052296157965 0.8726052296157965 0.0 cell_periphery GO:0071944 12133 2667 31 6 9983 31 1 false 0.8734695938602863 0.8734695938602863 0.0 single_organism_reproductive_process GO:0044702 12133 539 31 1 8107 30 2 false 0.8735366556465988 0.8735366556465988 0.0 maturation_of_SSU-rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000462 12133 7 31 1 8 1 1 false 0.8749999999999999 0.8749999999999999 0.12499999999999997 multicellular_organismal_development GO:0007275 12133 3069 31 4 4373 7 2 false 0.8764719566673371 0.8764719566673371 0.0 chromatin_organization GO:0006325 12133 539 31 2 689 3 1 false 0.8788682922734476 0.8788682922734476 4.375882251809235E-156 regulation_of_biological_process GO:0050789 12133 6622 31 17 10446 31 2 false 0.8794463221125817 0.8794463221125817 0.0 viral_genome_replication GO:0019079 12133 55 31 1 557 20 2 false 0.8796825558653665 0.8796825558653665 1.9020892479615726E-77 activating_transcription_factor_binding GO:0033613 12133 294 31 1 715 4 1 false 0.8805055006784788 0.8805055006784788 1.6086726333731214E-209 positive_regulation_of_apoptotic_process GO:0043065 12133 362 31 1 1377 7 3 false 0.8824145075684673 0.8824145075684673 0.0 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 31 1 1393 7 3 false 0.8838417676364535 0.8838417676364535 0.0 neuron_projection GO:0043005 12133 534 31 1 1043 3 2 false 0.8841258138002114 0.8841258138002114 5.7946905775E-313 hemopoiesis GO:0030097 12133 462 31 2 491 2 1 false 0.8852487634564072 0.8852487634564072 1.8682876304369947E-47 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 31 3 78 3 1 false 0.887599242862369 0.887599242862369 1.3144749986854762E-5 glucose_metabolic_process GO:0006006 12133 183 31 1 206 1 1 false 0.888349514563178 0.888349514563178 5.590923529140016E-31 biological_adhesion GO:0022610 12133 714 31 1 10446 31 1 false 0.8889820450829791 0.8889820450829791 0.0 extracellular_region_part GO:0044421 12133 740 31 1 10701 31 2 false 0.8918986522419307 0.8918986522419307 0.0 membrane_invagination GO:0010324 12133 411 31 1 784 3 1 false 0.892763877165275 0.892763877165275 8.658368437912315E-235 ion_binding GO:0043167 12133 4448 31 12 8962 30 1 false 0.8928378255059338 0.8928378255059338 0.0 gene_silencing_by_miRNA GO:0035195 12133 25 31 1 28 1 1 false 0.8928571428571428 0.8928571428571428 3.052503052503051E-4 positive_regulation_of_transport GO:0051050 12133 413 31 1 4769 25 3 false 0.8967442740906602 0.8967442740906602 0.0 positive_regulation_of_protein_transport GO:0051222 12133 154 31 1 1301 18 3 false 0.8980877225409989 0.8980877225409989 9.736449433094532E-205 positive_regulation_of_intracellular_protein_transport GO:0090316 12133 92 31 1 737 17 4 false 0.8990861602135869 0.8990861602135869 7.301092489476398E-120 protein_complex_biogenesis GO:0070271 12133 746 31 3 1525 9 1 false 0.8997115328560774 0.8997115328560774 0.0 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 31 6 378 6 1 false 0.9078751437642244 0.9078751437642244 2.5686196448553377E-13 cellular_response_to_stimulus GO:0051716 12133 4236 31 13 7871 30 2 false 0.9093387268434647 0.9093387268434647 0.0 regulation_of_programmed_cell_death GO:0043067 12133 1031 31 4 1410 7 2 false 0.9113102399330901 0.9113102399330901 0.0 mitochondrial_part GO:0044429 12133 557 31 1 7185 30 3 false 0.9115992669993485 0.9115992669993485 0.0 enzyme_regulator_activity GO:0030234 12133 771 31 1 10257 31 3 false 0.9116224111846354 0.9116224111846354 0.0 cell-cell_signaling GO:0007267 12133 859 31 1 3969 10 2 false 0.9130177983365462 0.9130177983365462 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 31 5 1180 21 1 false 0.9147132448625985 0.9147132448625985 0.0 regulation_of_apoptotic_process GO:0042981 12133 1019 31 4 1381 7 2 false 0.9182292253841724 0.9182292253841724 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I,_TAP-dependent GO:0002479 12133 70 31 2 73 2 1 false 0.9189497716895059 0.9189497716895059 1.607820438613435E-5 multicellular_organism_reproduction GO:0032504 12133 482 31 1 4643 23 2 false 0.9201220261007317 0.9201220261007317 0.0 membrane_organization GO:0061024 12133 787 31 3 3745 25 1 false 0.9213730026742865 0.9213730026742865 0.0 endoplasmic_reticulum_part GO:0044432 12133 593 31 1 7185 30 3 false 0.9249517257654114 0.9249517257654114 0.0 identical_protein_binding GO:0042802 12133 743 31 1 6397 21 1 false 0.9255112447264549 0.9255112447264549 0.0 positive_regulation_of_gene_expression GO:0010628 12133 1008 31 4 4103 27 3 false 0.9274467409182312 0.9274467409182312 0.0 organelle_envelope GO:0031967 12133 629 31 1 7756 31 3 false 0.9277174549248743 0.9277174549248743 0.0 nuclear_division GO:0000280 12133 326 31 1 351 1 1 false 0.9287749287750802 0.9287749287750802 8.671827254018066E-39 regulation_of_cellular_localization GO:0060341 12133 603 31 1 6869 29 3 false 0.9307640111086599 0.9307640111086599 0.0 purine_nucleotide_binding GO:0017076 12133 1650 31 4 1997 6 1 false 0.9309585698913158 0.9309585698913158 0.0 ribonucleotide_binding GO:0032553 12133 1651 31 4 1997 6 1 false 0.9314687281996884 0.9314687281996884 0.0 biological_regulation GO:0065007 12133 6908 31 17 10446 31 1 false 0.9333084947723659 0.9333084947723659 0.0 cell_activation GO:0001775 12133 656 31 1 7541 30 1 false 0.9351579680538761 0.9351579680538761 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 31 1 6358 16 2 false 0.9353332547188333 0.9353332547188333 0.0 RNA_processing GO:0006396 12133 601 31 2 3762 26 2 false 0.9362790175985652 0.9362790175985652 0.0 generation_of_neurons GO:0048699 12133 883 31 1 940 1 1 false 0.9393617021272437 0.9393617021272437 7.799501535546468E-93 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 31 14 4395 27 3 false 0.9403088088641701 0.9403088088641701 0.0 apoptotic_process GO:0006915 12133 1373 31 7 1385 7 1 false 0.9407789962372466 0.9407789962372466 1.0085392941984968E-29 chromosome GO:0005694 12133 592 31 2 3226 23 1 false 0.9423924569337871 0.9423924569337871 0.0 nervous_system_development GO:0007399 12133 1371 31 1 2686 4 1 false 0.942685277150912 0.942685277150912 0.0 cell_morphogenesis GO:0000902 12133 766 31 1 810 1 1 false 0.9456790123456539 0.9456790123456539 9.285456073507826E-74 transcription_cofactor_activity GO:0003712 12133 456 31 1 482 1 2 false 0.9460580912862344 0.9460580912862344 1.3948726648763881E-43 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 31 1 4947 26 2 false 0.9463218247556301 0.9463218247556301 0.0 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 31 11 6094 28 2 false 0.9467443126650126 0.9467443126650126 0.0 response_to_unfolded_protein GO:0006986 12133 126 31 1 133 1 1 false 0.9473684210526476 0.9473684210526476 8.038720251232349E-12 cell_adhesion GO:0007155 12133 712 31 1 7542 30 2 false 0.9492534122774628 0.9492534122774628 0.0 hexose_metabolic_process GO:0019318 12133 206 31 1 217 1 1 false 0.9493087557602818 0.9493087557602818 1.0279992997812003E-18 regulation_of_cellular_process GO:0050794 12133 6304 31 16 9757 31 2 false 0.953482734132317 0.953482734132317 0.0 cell_projection_organization GO:0030030 12133 744 31 1 7663 30 2 false 0.9535830080056356 0.9535830080056356 0.0 regulation_of_protein_transport GO:0051223 12133 261 31 1 1665 18 3 false 0.9543253185100347 0.9543253185100347 3.65102727546E-313 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 31 1 614 1 1 false 0.9543973941371671 0.9543973941371671 4.862693095923331E-49 purine_ribonucleotide_binding GO:0032555 12133 1641 31 4 1660 4 2 false 0.9549569007756471 0.9549569007756471 8.870449707822982E-45 regulation_of_intracellular_transport GO:0032386 12133 276 31 1 1731 18 3 false 0.9568629034541094 0.9568629034541094 0.0 response_to_external_stimulus GO:0009605 12133 1046 31 1 5200 14 1 false 0.9570892028829279 0.9570892028829279 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 31 4 2805 4 1 false 0.959260743642875 0.959260743642875 1.0460685646312495E-69 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 31 3 149 3 1 false 0.9600036277888687 0.9600036277888687 9.06947215672054E-5 regulation_of_protein_localization GO:0032880 12133 349 31 1 2148 19 2 false 0.966100670817631 0.966100670817631 0.0 single_organism_signaling GO:0044700 12133 3878 31 10 8052 30 2 false 0.9662795011018122 0.9662795011018122 0.0 cell_proliferation GO:0008283 12133 1316 31 2 8052 30 1 false 0.9677637354264913 0.9677637354264913 0.0 viral_reproduction GO:0016032 12133 633 31 20 634 20 1 false 0.9684542586750651 0.9684542586750651 0.0015772870662463625 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 31 11 5532 27 4 false 0.9692350315290903 0.9692350315290903 0.0 regulation_of_gene_expression GO:0010468 12133 2935 31 14 4361 27 2 false 0.9698793670416389 0.9698793670416389 0.0 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 31 3 199 3 1 false 0.9700015227652451 0.9700015227652451 5.075884472869322E-5 extracellular_region GO:0005576 12133 1152 31 1 10701 31 1 false 0.9708755252876029 0.9708755252876029 0.0 regulation_of_intracellular_protein_transport GO:0033157 12133 160 31 1 847 17 3 false 0.972598993285585 0.972598993285585 1.5386851760422239E-177 developmental_induction GO:0031128 12133 38 31 1 39 1 1 false 0.9743589743589666 0.9743589743589666 0.02564102564102553 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 31 11 4544 27 3 false 0.9744006111946824 0.9744006111946824 0.0 membrane GO:0016020 12133 4398 31 8 10701 31 1 false 0.9751772145654883 0.9751772145654883 0.0 signaling_receptor_activity GO:0038023 12133 633 31 1 1211 5 2 false 0.9754542756140617 0.9754542756140617 0.0 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 31 1 207 1 1 false 0.9758454106280321 0.9758454106280321 3.3148479610294504E-10 nucleocytoplasmic_transport GO:0006913 12133 327 31 2 331 2 1 false 0.9759406756385482 0.9759406756385482 2.036102168267257E-9 integral_to_membrane GO:0016021 12133 2318 31 1 2375 1 1 false 0.9760000000014666 0.9760000000014666 3.0839384482043954E-116 protein_import_into_nucleus GO:0006606 12133 200 31 2 690 17 5 false 0.9776305317524713 0.9776305317524713 1.1794689955817937E-179 chromatin_modification GO:0016568 12133 458 31 1 539 2 1 false 0.97765378540757 0.97765378540757 1.802023694196357E-98 purine_nucleoside_binding GO:0001883 12133 1631 31 4 1639 4 1 false 0.9806007488464052 0.9806007488464052 7.876250956196666E-22 nuclear_transport GO:0051169 12133 331 31 2 1148 18 1 false 0.9824599520135375 0.9824599520135375 1.3196682196913852E-298 protein_deacetylation GO:0006476 12133 57 31 1 58 1 1 false 0.982758620689673 0.982758620689673 0.017241379310345032 purine_ribonucleoside_binding GO:0032550 12133 1629 31 4 1635 4 2 false 0.9853883665513075 0.9853883665513075 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 31 4 1639 4 1 false 0.9854238628325719 0.9854238628325719 3.7483303336303164E-17 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 31 1 723 4 2 false 0.9861535056678041 0.9861535056678041 2.0953844092707462E-201 chordate_embryonic_development GO:0043009 12133 471 31 1 477 1 1 false 0.9874213836479633 0.9874213836479633 6.308586670641318E-14 regulation_of_translational_initiation GO:0006446 12133 60 31 1 300 19 2 false 0.9875891303874371 0.9875891303874371 1.1059627794090193E-64 cellular_developmental_process GO:0048869 12133 2267 31 4 7817 30 2 false 0.9876248349709318 0.9876248349709318 0.0 response_to_wounding GO:0009611 12133 905 31 1 2540 10 1 false 0.9879060566321771 0.9879060566321771 0.0 nucleoside_phosphate_binding GO:1901265 12133 1998 31 6 4407 24 2 false 0.9884911512469483 0.9884911512469483 0.0 multicellular_organismal_process GO:0032501 12133 4223 31 7 10446 31 1 false 0.9889668893288005 0.9889668893288005 0.0 cellular_component_morphogenesis GO:0032989 12133 810 31 1 5068 26 4 false 0.9893272140786181 0.9893272140786181 0.0 cell_communication GO:0007154 12133 3962 31 10 7541 30 1 false 0.9895113252224024 0.9895113252224024 0.0 mitochondrion GO:0005739 12133 1138 31 1 8213 31 2 false 0.9902725813471182 0.9902725813471182 0.0 intrinsic_to_membrane GO:0031224 12133 2375 31 1 2995 3 1 false 0.9911627839229261 0.9911627839229261 0.0 nucleoside_binding GO:0001882 12133 1639 31 4 4455 24 3 false 0.9917335414923634 0.9917335414923634 0.0 hydrolase_activity GO:0016787 12133 2556 31 3 4901 13 1 false 0.9926347000429838 0.9926347000429838 0.0 DNA_binding GO:0003677 12133 2091 31 10 2849 20 1 false 0.9935723586806803 0.9935723586806803 0.0 regulation_of_localization GO:0032879 12133 1242 31 1 7621 30 2 false 0.9952424975366161 0.9952424975366161 0.0 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 31 1 1192 18 2 false 0.9954148029048584 0.9954148029048584 5.168872172755415E-294 translation_initiation_factor_activity GO:0003743 12133 50 31 1 191 17 2 false 0.9956203242475912 0.9956203242475912 3.1223441687767467E-47 spermatogenesis GO:0007283 12133 270 31 1 271 1 1 false 0.9963099630996762 0.9963099630996762 0.0036900369003690227 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 31 6 672 20 1 false 0.9963348138370534 0.9963348138370534 6.935915883902889E-199 ion_transport GO:0006811 12133 833 31 2 2323 18 1 false 0.996362659847878 0.996362659847878 0.0 cytoskeletal_part GO:0044430 12133 1031 31 1 5573 28 2 false 0.9967958315340696 0.9967958315340696 0.0 membrane_part GO:0044425 12133 2995 31 3 10701 31 2 false 0.9968687824339368 0.9968687824339368 0.0 transcription,_DNA-dependent GO:0006351 12133 2643 31 11 4063 27 3 false 0.9973177714522203 0.9973177714522203 0.0 developmental_process GO:0032502 12133 3447 31 4 10446 31 1 false 0.9973250970562453 0.9973250970562453 0.0 response_to_other_organism GO:0051707 12133 475 31 3 1194 21 2 false 0.9976459975911979 0.9976459975911979 0.0 single-organism_developmental_process GO:0044767 12133 2776 31 4 8064 30 2 false 0.9977318970477561 0.9977318970477561 0.0 protein_modification_process GO:0036211 12133 2370 31 11 3518 26 2 false 0.9977621272836635 0.9977621272836635 0.0 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 31 23 7976 31 2 false 0.9988001992245282 0.9988001992245282 0.0 regulation_of_transport GO:0051049 12133 942 31 1 3017 18 2 false 0.9988414252103932 0.9988414252103932 0.0 membrane-bounded_organelle GO:0043227 12133 7284 31 23 7980 31 1 false 0.9990344501242595 0.9990344501242595 0.0 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 31 1 7451 29 1 false 0.9990374204206436 0.9990374204206436 0.0 vesicle-mediated_transport GO:0016192 12133 895 31 1 2783 18 1 false 0.9990975550892245 0.9990975550892245 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 31 13 3611 26 3 false 0.9991960563903824 0.9991960563903824 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 31 4 7256 29 1 false 0.9992480976447606 0.9992480976447606 0.0 macromolecular_complex_assembly GO:0065003 12133 973 31 6 1603 21 2 false 0.9993849674099969 0.9993849674099969 0.0 single-multicellular_organism_process GO:0044707 12133 4095 31 7 8057 30 2 false 0.9994860981565801 0.9994860981565801 0.0 sexual_reproduction GO:0019953 12133 407 31 1 1345 21 1 false 0.9995177185328976 0.9995177185328976 0.0 protein_localization_to_nucleus GO:0034504 12133 233 31 2 516 17 1 false 0.9995346626720466 0.9995346626720466 1.4955266190313754E-153 protein_targeting_to_nucleus GO:0044744 12133 200 31 2 443 17 1 false 0.9995468715324217 0.9995468715324217 9.352491047681514E-132 cytoskeleton GO:0005856 12133 1430 31 3 3226 23 1 false 0.9997564208130774 0.9997564208130774 0.0 virus-host_interaction GO:0019048 12133 355 31 5 588 20 2 false 0.9997777383907032 0.9997777383907032 1.0104535019427035E-170 multicellular_organismal_reproductive_process GO:0048609 12133 477 31 1 1275 21 2 false 0.9999518069136767 0.9999518069136767 0.0 cellular_protein_modification_process GO:0006464 12133 2370 31 11 3038 26 2 false 0.9999856691746101 0.9999856691746101 0.0 mRNA_processing GO:0006397 12133 374 31 1 763 17 2 false 0.9999910839722356 0.9999910839722356 8.270510506831645E-229 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 31 11 3220 26 4 false 0.9999947210659018 0.9999947210659018 0.0 single-organism_metabolic_process GO:0044710 12133 2877 31 1 8027 29 1 false 0.9999974993398708 0.9999974993398708 0.0 protein_complex_assembly GO:0006461 12133 743 31 3 1214 21 3 false 0.9999989417468714 0.9999989417468714 0.0 protein_complex GO:0043234 12133 2976 31 7 3462 25 1 false 0.9999999999933401 0.9999999999933401 0.0 GO:0000000 12133 11221 31 31 0 0 0 true 1.0 1.0 1.0 DNA-directed_RNA_polymerase_complex GO:0000428 12133 136 31 1 136 1 1 true 1.0 1.0 1.0 endonucleolytic_cleavage_involved_in_rRNA_processing GO:0000478 12133 4 31 1 4 1 2 true 1.0 1.0 1.0 endonucleolytic_cleavage_of_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000479 12133 4 31 1 4 1 1 true 1.0 1.0 1.0 7-methylguanosine_RNA_capping GO:0009452 12133 32 31 1 32 1 1 true 1.0 1.0 1.0 eukaryotic_43S_preinitiation_complex GO:0016282 12133 14 31 1 14 1 1 true 1.0 1.0 1.0 entry_into_host_cell GO:0030260 12133 21 31 1 21 1 2 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 31 2 147 2 1 true 1.0 1.0 1.0 eukaryotic_48S_preinitiation_complex GO:0033290 12133 14 31 1 14 1 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 31 7 1169 7 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 31 5 417 5 1 true 1.0 1.0 1.0 entry_into_host GO:0044409 12133 21 31 1 21 1 2 true 1.0 1.0 1.0 evasion_or_tolerance_of_host_defenses GO:0044415 12133 3 31 1 3 1 2 true 1.0 1.0 1.0 iron-sulfur_cluster_binding GO:0051536 12133 47 31 1 47 1 1 true 1.0 1.0 1.0 entry_into_cell_of_other_organism_involved_in_symbiotic_interaction GO:0051806 12133 21 31 1 21 1 1 true 1.0 1.0 1.0 entry_into_other_organism_involved_in_symbiotic_interaction GO:0051828 12133 21 31 1 21 1 1 true 1.0 1.0 1.0 evasion_or_tolerance_of_defenses_of_other_organism_involved_in_symbiotic_interaction GO:0051834 12133 3 31 1 3 1 1 true 1.0 1.0 1.0 response_to_host_defenses GO:0052200 12133 8 31 1 8 1 2 true 1.0 1.0 1.0 RNA_phosphodiester_bond_hydrolysis,_endonucleolytic GO:0090502 12133 4 31 1 4 1 1 true 1.0 1.0 1.0