ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min mRNA_metabolic_process GO:0016071 12133 573 45 29 3294 39 1 false 5.669413378138403E-15 5.669413378138403E-15 0.0 ribonucleoprotein_complex GO:0030529 12133 569 45 21 9264 45 2 false 2.3546157499310235E-14 2.3546157499310235E-14 0.0 RNA_processing GO:0006396 12133 601 45 28 3762 40 2 false 2.367686069334307E-14 2.367686069334307E-14 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 45 36 10701 45 1 false 6.183421606058721E-13 6.183421606058721E-13 0.0 spliceosomal_complex GO:0005681 12133 150 45 15 3020 40 2 false 1.8994693000679573E-10 1.8994693000679573E-10 2.455159410572961E-258 RNA_binding GO:0003723 12133 763 45 28 2849 36 1 false 1.9668388074002713E-10 1.9668388074002713E-10 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 45 42 6846 44 2 false 3.285622934175728E-9 3.285622934175728E-9 0.0 nuclear_part GO:0044428 12133 2767 45 37 6936 45 2 false 6.537815582897203E-9 6.537815582897203E-9 0.0 Prp19_complex GO:0000974 12133 78 45 8 2976 19 1 false 9.285763580586475E-9 9.285763580586475E-9 3.570519754703887E-156 nucleus GO:0005634 12133 4764 45 43 7259 43 1 false 1.2783477170065453E-8 1.2783477170065453E-8 0.0 organelle_part GO:0044422 12133 5401 45 40 10701 45 2 false 5.190880030091693E-8 5.190880030091693E-8 0.0 nucleic_acid_binding GO:0003676 12133 2849 45 36 4407 36 2 false 1.398276353252595E-7 1.398276353252595E-7 0.0 macromolecular_complex GO:0032991 12133 3462 45 31 10701 45 1 false 5.340149034570718E-7 5.340149034570718E-7 0.0 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 45 3 6481 28 2 false 1.4322665457457936E-6 1.4322665457457936E-6 9.738359623180132E-21 intracellular_organelle_lumen GO:0070013 12133 2919 45 36 5320 40 2 false 1.6639447872285822E-6 1.6639447872285822E-6 0.0 organelle_lumen GO:0043233 12133 2968 45 36 5401 40 2 false 1.7487972119575676E-6 1.7487972119575676E-6 0.0 organelle GO:0043226 12133 7980 45 45 10701 45 1 false 1.7876771983441899E-6 1.7876771983441899E-6 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 45 44 7569 44 2 false 1.8530489840496343E-6 1.8530489840496343E-6 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 45 42 8027 44 1 false 2.031059444952757E-6 2.031059444952757E-6 0.0 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 45 9 3020 40 2 false 2.1006245902178364E-6 2.1006245902178364E-6 1.1070924240418437E-179 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 45 42 7341 44 5 false 2.880708206051987E-6 2.880708206051987E-6 0.0 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 45 42 7451 44 1 false 8.13690396077718E-6 8.13690396077718E-6 0.0 intracellular_organelle_part GO:0044446 12133 5320 45 40 9083 45 3 false 8.733217416218085E-6 8.733217416218085E-6 0.0 cellular_metabolic_process GO:0044237 12133 7256 45 44 10007 45 2 false 9.132578302665505E-6 9.132578302665505E-6 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 45 42 7256 44 1 false 9.352980663439544E-6 9.352980663439544E-6 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 45 42 7256 44 1 false 9.873922451028958E-6 9.873922451028958E-6 0.0 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 45 8 1256 14 1 false 1.0206329015949871E-5 1.0206329015949871E-5 3.1457660386089413E-171 gene_expression GO:0010467 12133 3708 45 40 6052 44 1 false 1.0435489300041378E-5 1.0435489300041378E-5 0.0 RNA_metabolic_process GO:0016070 12133 3294 45 39 5627 44 2 false 1.2801397916826415E-5 1.2801397916826415E-5 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 45 36 8962 45 1 false 1.4606055490228308E-5 1.4606055490228308E-5 0.0 organic_cyclic_compound_binding GO:0097159 12133 4407 45 36 8962 45 1 false 1.986090689999058E-5 1.986090689999058E-5 0.0 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 45 9 1525 13 1 false 2.296829869497107E-5 2.296829869497107E-5 1.2095302863090285E-289 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 45 42 7275 44 2 false 2.457627063914141E-5 2.457627063914141E-5 0.0 ribonucleoprotein_complex_assembly GO:0022618 12133 117 45 8 646 10 3 false 3.065535876856989E-5 3.065535876856989E-5 4.631331466925404E-132 RNA_splicing GO:0008380 12133 307 45 24 601 28 1 false 1.0113690894608717E-4 1.0113690894608717E-4 4.262015823312228E-180 metabolic_process GO:0008152 12133 8027 45 44 10446 45 1 false 1.0118577038228174E-4 1.0118577038228174E-4 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 45 44 7451 44 1 false 1.0311215815900698E-4 1.0311215815900698E-4 0.0 termination_of_RNA_polymerase_II_transcription GO:0006369 12133 44 45 5 1385 17 2 false 1.1975980758614123E-4 1.1975980758614123E-4 3.166663017097352E-84 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 45 5 201 5 3 false 1.6763109433064554E-4 1.6763109433064554E-4 2.854176062301069E-41 establishment_of_RNA_localization GO:0051236 12133 124 45 5 2839 14 2 false 2.1381050903766812E-4 2.1381050903766812E-4 1.4765023034812589E-220 translational_initiation GO:0006413 12133 160 45 5 7667 28 2 false 2.477505358430323E-4 2.477505358430323E-4 0.0 cytosolic_part GO:0044445 12133 178 45 5 5117 19 2 false 3.7637574614168297E-4 3.7637574614168297E-4 0.0 mRNA_processing GO:0006397 12133 374 45 24 763 30 2 false 3.929454522872259E-4 3.929454522872259E-4 8.270510506831645E-229 macromolecular_complex_subunit_organization GO:0043933 12133 1256 45 14 3745 19 1 false 3.9603929158168175E-4 3.9603929158168175E-4 0.0 multi-organism_cellular_process GO:0044764 12133 634 45 10 9702 45 2 false 5.224814084335797E-4 5.224814084335797E-4 0.0 small_molecule_binding GO:0036094 12133 2102 45 21 8962 45 1 false 5.249287212048322E-4 5.249287212048322E-4 0.0 nucleobase-containing_compound_transport GO:0015931 12133 135 45 5 1584 10 2 false 7.424695563303026E-4 7.424695563303026E-4 1.0378441909200412E-199 DNA-dependent_transcription,_termination GO:0006353 12133 80 45 5 2751 27 2 false 8.957635056649435E-4 8.957635056649435E-4 1.5820458311792457E-156 ribosomal_subunit GO:0044391 12133 132 45 5 7199 43 4 false 0.001057246003657694 0.001057246003657694 2.5906239763169356E-285 Mre11_complex GO:0030870 12133 6 45 2 4399 38 2 false 0.0010665146593014877 0.0010665146593014877 9.96988681802558E-20 nuclear_lumen GO:0031981 12133 2490 45 36 3186 37 2 false 0.0011861788501496885 0.0011861788501496885 0.0 helicase_activity GO:0004386 12133 140 45 4 1059 5 1 false 0.0013192358497582993 0.0013192358497582993 6.632628106941949E-179 ribosome GO:0005840 12133 210 45 6 6755 40 3 false 0.001332741205806624 0.001332741205806624 0.0 regulation_of_RNA_stability GO:0043487 12133 37 45 3 2240 14 2 false 0.0013330858670916562 0.0013330858670916562 2.0388833014238124E-81 RNA_localization GO:0006403 12133 131 45 5 1642 12 1 false 0.0015022054977856252 0.0015022054977856252 1.0675246049472868E-197 structural_constituent_of_ribosome GO:0003735 12133 152 45 5 526 5 1 false 0.0019218135525632587 0.0019218135525632587 1.18011379183299E-136 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 45 20 374 24 2 false 0.002037454350884024 0.002037454350884024 2.0954491420584897E-111 structure-specific_DNA_binding GO:0043566 12133 179 45 5 2091 12 1 false 0.00209424797738518 0.00209424797738518 1.2928223396172998E-264 binding GO:0005488 12133 8962 45 45 10257 45 1 false 0.002271069070078511 0.002271069070078511 0.0 nuclear_export GO:0051168 12133 116 45 6 688 10 2 false 0.0023894465650440206 0.0023894465650440206 6.892155989004194E-135 intracellular_organelle GO:0043229 12133 7958 45 45 9096 45 2 false 0.0024050473845869604 0.0024050473845869604 0.0 histone_pre-mRNA_3'end_processing_complex GO:0071204 12133 6 45 2 3020 40 2 false 0.0024815336466915893 0.0024815336466915893 9.537822615543818E-19 translational_termination GO:0006415 12133 92 45 5 513 7 2 false 0.0026154238505750253 0.0026154238505750253 3.4634519853301643E-104 protein_complex_disassembly GO:0043241 12133 154 45 5 1031 8 2 false 0.0026775694523056967 0.0026775694523056967 4.7545827865276796E-188 response_to_methylglyoxal GO:0051595 12133 1 45 1 1822 5 2 false 0.002744237102082279 0.002744237102082279 5.488474204168676E-4 multi-organism_process GO:0051704 12133 1180 45 12 10446 45 1 false 0.0033735649314315386 0.0033735649314315386 0.0 protein_targeting_to_membrane GO:0006612 12133 145 45 5 443 5 1 false 0.003584199765355926 0.003584199765355926 5.648405296311656E-121 negative_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060266 12133 3 45 1 738 1 8 false 0.004065040650405498 0.004065040650405498 1.4988203684165303E-8 cytoplasmic_transport GO:0016482 12133 666 45 10 1148 10 1 false 0.004196715758109199 0.004196715758109199 0.0 translational_elongation GO:0006414 12133 121 45 5 3388 31 2 false 0.004311857223226152 0.004311857223226152 5.332026529203484E-226 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 45 5 1239 8 2 false 0.004822773366721623 0.004822773366721623 4.427655683668096E-244 cellular_process_involved_in_reproduction GO:0048610 12133 469 45 7 9699 45 2 false 0.005434693666470646 0.005434693666470646 0.0 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 45 3 22 3 1 false 0.006493506493506468 0.006493506493506468 3.79737221842484E-5 laminin_receptor_activity GO:0005055 12133 2 45 1 807 3 2 false 0.007425719741344356 0.007425719741344356 3.0748321910333906E-6 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 45 5 516 7 1 false 0.0075643209539283385 0.0075643209539283385 8.917305549619806E-119 nucleoplasm GO:0005654 12133 1443 45 27 2767 37 2 false 0.007654835982382492 0.007654835982382492 0.0 protein_targeting_to_ER GO:0045047 12133 104 45 5 721 10 3 false 0.007874624975346623 0.007874624975346623 1.514347826459292E-128 paraspeckles GO:0042382 12133 6 45 2 272 7 1 false 0.008131732047607977 0.008131732047607977 1.8794561691225117E-12 negative_regulation_of_muscle_cell_differentiation GO:0051148 12133 33 45 2 584 3 3 false 0.008974321396881084 0.008974321396881084 1.1148204606376211E-54 regulation_of_muscle_cell_differentiation GO:0051147 12133 103 45 3 987 5 2 false 0.009450063993803525 0.009450063993803525 9.48284116235963E-143 reproduction GO:0000003 12133 1345 45 12 10446 45 1 false 0.009674653072638253 0.009674653072638253 0.0 biosynthetic_process GO:0009058 12133 4179 45 31 8027 44 1 false 0.010001112955659374 0.010001112955659374 0.0 positive_regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060265 12133 2 45 1 589 3 7 false 0.010169432798585589 0.010169432798585589 5.774805677789514E-6 viral_transcription GO:0019083 12133 145 45 5 2964 28 3 false 0.010319620950829368 0.010319620950829368 1.0927707330622845E-250 cellular_component_biogenesis GO:0044085 12133 1525 45 13 3839 19 1 false 0.010656842029560208 0.010656842029560208 0.0 regulation_of_ATP_biosynthetic_process GO:2001169 12133 3 45 1 516 2 3 false 0.011605328516593199 0.011605328516593199 4.3926965270440784E-8 negative_regulation_of_DNA-dependent_DNA_replication GO:2000104 12133 13 45 2 115 2 3 false 0.01189931350114451 0.01189931350114451 2.046754411614714E-17 RNA-dependent_DNA_replication GO:0006278 12133 17 45 2 257 3 1 false 0.011916342412450813 0.011916342412450813 6.56310052416544E-27 cytosolic_ribosome GO:0022626 12133 92 45 5 296 6 2 false 0.012104380893537848 0.012104380893537848 4.2784789004852985E-79 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 45 17 2643 22 1 false 0.012372238142873575 0.012372238142873575 0.0 cellular_component_disassembly GO:0022411 12133 351 45 5 7663 31 2 false 0.012460406663064265 0.012460406663064265 0.0 positive_regulation_of_energy_homeostasis GO:2000507 12133 2 45 1 477 3 4 false 0.012552190687597678 0.012552190687597678 8.808554868491117E-6 regulation_of_protein_acetylation GO:1901983 12133 34 45 2 1097 6 2 false 0.012941433020418664 0.012941433020418664 2.1258425781065562E-65 positive_regulation_of_ATP_biosynthetic_process GO:2001171 12133 2 45 1 154 1 4 false 0.012987012987012915 0.012987012987012915 8.488243782360448E-5 ATP_metabolic_process GO:0046034 12133 381 45 5 1209 6 3 false 0.013548338378414137 0.013548338378414137 0.0 positive_regulation_of_chromatin_silencing GO:0031937 12133 3 45 1 2824 13 3 false 0.013751570225854584 0.013751570225854584 2.6669733159706177E-10 response_to_stress GO:0006950 12133 2540 45 12 5200 15 1 false 0.013960848173336626 0.013960848173336626 0.0 regulation_of_respiratory_burst_involved_in_inflammatory_response GO:0060264 12133 4 45 1 1701 6 6 false 0.014047197978466687 0.014047197978466687 2.8769144126071423E-12 primary_metabolic_process GO:0044238 12133 7288 45 44 8027 44 1 false 0.014099858911253472 0.014099858911253472 0.0 intracellular_part GO:0044424 12133 9083 45 45 9983 45 2 false 0.014102304898676237 0.014102304898676237 0.0 macromolecule_biosynthetic_process GO:0009059 12133 3475 45 31 6537 44 2 false 0.014519595085747069 0.014519595085747069 0.0 multi-organism_reproductive_process GO:0044703 12133 707 45 10 1275 11 1 false 0.014664697659050306 0.014664697659050306 0.0 negative_regulation_of_protein_localization_to_nucleus GO:1900181 12133 3 45 1 2595 13 3 false 0.014959475443077406 0.014959475443077406 3.4374896537028804E-10 response_to_osmotic_stress GO:0006970 12133 43 45 2 2681 12 2 false 0.014979520622048046 0.014979520622048046 3.246680302266631E-95 snRNA_binding GO:0017069 12133 15 45 3 763 28 1 false 0.014995470731084065 0.014995470731084065 8.685184804619145E-32 maturation_of_SSU-rRNA GO:0030490 12133 8 45 2 104 3 2 false 0.015068312612572342 0.015068312612572342 3.8823564737710265E-12 cellular_localization GO:0051641 12133 1845 45 12 7707 27 2 false 0.015262994490453643 0.015262994490453643 0.0 cellular_component_assembly GO:0022607 12133 1392 45 12 3836 19 2 false 0.015434981651744648 0.015434981651744648 0.0 basal_transcription_machinery_binding GO:0001098 12133 464 45 7 6397 37 1 false 0.015467289878591412 0.015467289878591412 0.0 positive_regulation_of_nucleoside_metabolic_process GO:0045979 12133 3 45 1 2103 11 3 false 0.015617323266652243 0.015617323266652243 6.460307848228921E-10 progressive_alteration_of_chromatin_involved_in_cell_aging GO:0001301 12133 2 45 1 509 4 2 false 0.015670683600694114 0.015670683600694114 7.73478953637772E-6 regulation_of_transporter_activity GO:0032409 12133 88 45 2 2973 7 3 false 0.016514044138644494 0.016514044138644494 1.555650039308817E-171 reproductive_process GO:0022414 12133 1275 45 11 10446 45 2 false 0.01712235464477372 0.01712235464477372 0.0 protein_acylation GO:0043543 12133 155 45 3 2370 9 1 false 0.017199916436605588 0.017199916436605588 6.767829300235778E-248 molecular_function GO:0003674 12133 10257 45 45 11221 45 1 false 0.017413437592995712 0.017413437592995712 0.0 small_ribosomal_subunit GO:0015935 12133 60 45 5 132 5 1 false 0.017656551242117884 0.017656551242117884 4.556510204279982E-39 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 45 3 243 9 2 false 0.01848759273618207 0.01848759273618207 1.7559807727942103E-26 protein_binding_transcription_factor_activity GO:0000988 12133 488 45 6 10311 45 3 false 0.018518773658022764 0.018518773658022764 0.0 mRNA_splice_site_selection GO:0006376 12133 18 45 4 117 8 2 false 0.018999267131837798 0.018999267131837798 1.505085052005422E-21 ribose_phosphate_metabolic_process GO:0019693 12133 1207 45 6 3007 7 3 false 0.019091934602469635 0.019091934602469635 0.0 intracellular_transport GO:0046907 12133 1148 45 10 2815 14 2 false 0.020084807956473695 0.020084807956473695 0.0 nucleoside_metabolic_process GO:0009116 12133 1083 45 6 2072 6 4 false 0.02025599938871698 0.02025599938871698 0.0 RS_domain_binding GO:0050733 12133 5 45 1 486 2 1 false 0.02049128165966221 0.02049128165966221 4.51818185951414E-12 nuclear_body GO:0016604 12133 272 45 7 805 10 1 false 0.02059997324331801 0.02059997324331801 8.12188174084084E-223 intracellular GO:0005622 12133 9171 45 45 9983 45 1 false 0.02178601799264479 0.02178601799264479 0.0 positive_regulation_of_homeostatic_process GO:0032846 12133 51 45 2 3482 16 3 false 0.022141821429555626 0.022141821429555626 5.214077402857871E-115 RNA_helicase_activity GO:0003724 12133 27 45 3 140 4 1 false 0.0227060496953122 0.0227060496953122 1.8047202528374888E-29 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 45 5 220 5 2 false 0.02353664919289961 0.02353664919289961 1.3850176335002185E-65 macromolecule_localization GO:0033036 12133 1642 45 12 3467 16 1 false 0.023540641428223767 0.023540641428223767 0.0 regulation_of_DNA-dependent_DNA_replication GO:0090329 12133 25 45 2 159 2 2 false 0.02388344877000262 0.02388344877000262 1.0490694573587729E-29 tRNA-splicing_ligase_complex GO:0072669 12133 5 45 1 9248 45 2 false 0.024099124195148112 0.024099124195148112 1.775872679278938E-18 protein_targeting GO:0006605 12133 443 45 5 2378 10 2 false 0.024302520928449756 0.024302520928449756 0.0 chromosome,_telomeric_region GO:0000781 12133 48 45 2 512 3 1 false 0.02431291009553834 0.02431291009553834 1.088424225361165E-68 negative_regulation_of_chromosome_organization GO:2001251 12133 42 45 2 797 5 3 false 0.02451118431154545 0.02451118431154545 5.8071042649554035E-71 transition_metal_ion_binding GO:0046914 12133 1457 45 6 2699 6 1 false 0.024630800812799006 0.024630800812799006 0.0 nuclear_export_signal_receptor_activity GO:0005049 12133 3 45 1 121 1 2 false 0.02479338842975232 0.02479338842975232 3.4724633655116144E-6 nucleotidyltransferase_activity GO:0016779 12133 123 45 2 1304 3 1 false 0.02485349191780578 0.02485349191780578 3.0641101871346933E-176 ATPase_activity GO:0016887 12133 307 45 4 1069 5 2 false 0.025904293056529564 0.025904293056529564 1.5605649392254874E-277 negative_regulation_of_respiratory_burst GO:0060268 12133 3 45 1 1370 12 3 false 0.026066746419598927 0.026066746419598927 2.3385202648234984E-9 cellular_protein_localization GO:0034613 12133 914 45 8 1438 8 2 false 0.026340778786013524 0.026340778786013524 0.0 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 45 31 6146 44 3 false 0.027203309058294094 0.027203309058294094 0.0 release_from_viral_latency GO:0019046 12133 2 45 1 355 5 2 false 0.02800986711228314 0.02800986711228314 1.591469722288648E-5 cellular_response_to_stress GO:0033554 12133 1124 45 7 4743 14 2 false 0.02882235640911347 0.02882235640911347 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 45 31 7470 44 2 false 0.029125920421989686 0.029125920421989686 0.0 positive_regulation_of_gluconeogenesis GO:0045722 12133 6 45 1 1223 6 4 false 0.029136023528378997 0.029136023528378997 2.1782531209525989E-16 regulation_of_chromosome_organization GO:0033044 12133 114 45 3 1070 7 2 false 0.029944599980602192 0.029944599980602192 5.856752364330647E-157 regulation_of_energy_homeostasis GO:2000505 12133 8 45 1 1583 6 3 false 0.02998844406254562 0.02998844406254562 1.040799649171348E-21 nucleolus GO:0005730 12133 1357 45 19 4208 40 3 false 0.031062581728955672 0.031062581728955672 0.0 cellular_process GO:0009987 12133 9675 45 45 10446 45 1 false 0.03149583576421484 0.03149583576421484 0.0 respiratory_burst_involved_in_defense_response GO:0002679 12133 9 45 1 1100 4 3 false 0.032371439784106386 0.032371439784106386 1.590299388551981E-22 viral_reproductive_process GO:0022415 12133 557 45 10 783 10 2 false 0.032412126507206464 0.032412126507206464 1.4346997744229993E-203 ATP-dependent_helicase_activity GO:0008026 12133 98 45 4 228 4 2 false 0.03294131916018363 0.03294131916018363 4.1384935546953996E-67 male_sex_determination GO:0030238 12133 13 45 1 3069 8 2 false 0.03342666739813937 0.03342666739813937 2.9810795844016348E-36 telomere_maintenance_in_response_to_DNA_damage GO:0043247 12133 4 45 1 590 5 2 false 0.0335541648171193 0.0335541648171193 2.000914391865E-10 positive_regulation_of_respiratory_burst GO:0060267 12133 5 45 1 1885 13 3 false 0.034046047105899355 0.034046047105899355 5.069092992061398E-15 negative_regulation_of_DNA_replication GO:0008156 12133 35 45 2 1037 9 4 false 0.03433971893238439 0.03433971893238439 5.175732417390482E-66 cellular_biosynthetic_process GO:0044249 12133 4077 45 31 7290 44 2 false 0.03464261823494211 0.03464261823494211 0.0 cellular_sodium_ion_homeostasis GO:0006883 12133 5 45 1 283 2 3 false 0.03508508132220518 0.03508508132220518 6.84978827344915E-11 regulation_of_DNA_endoreduplication GO:0032875 12133 7 45 1 389 2 3 false 0.03571144621419081 0.03571144621419081 3.947846080793853E-15 negative_regulation_of_sodium_ion_transport GO:0010766 12133 5 45 1 135 1 3 false 0.03703703703703773 0.03703703703703773 2.884335739945468E-9 organic_substance_metabolic_process GO:0071704 12133 7451 45 44 8027 44 1 false 0.03742188293167165 0.03742188293167165 0.0 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 45 6 2935 22 1 false 0.03853087492411135 0.03853087492411135 0.0 regulation_of_organelle_organization GO:0033043 12133 519 45 5 2487 10 2 false 0.03856272613378494 0.03856272613378494 0.0 negative_regulation_of_mRNA_processing GO:0050686 12133 13 45 2 1096 27 3 false 0.038578296606238606 0.038578296606238606 2.031276795679201E-30 nuclear_transport GO:0051169 12133 331 45 6 1148 10 1 false 0.03863017329583109 0.03863017329583109 1.3196682196913852E-298 macromolecular_complex_disassembly GO:0032984 12133 199 45 5 1380 14 2 false 0.0394275937825532 0.0394275937825532 1.9082717261040364E-246 biological_process GO:0008150 12133 10446 45 45 11221 45 1 false 0.039671633752355134 0.039671633752355134 0.0 negative_regulation_of_DNA_endoreduplication GO:0032876 12133 5 45 1 250 2 4 false 0.03967871485943928 0.03967871485943928 1.2792580221601644E-10 positive_regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033145 12133 9 45 1 856 4 3 false 0.04146903386423576 0.04146903386423576 1.5339974177634096E-21 muscle_cell_differentiation GO:0042692 12133 267 45 3 2218 7 2 false 0.04172025099291707 0.04172025099291707 0.0 positive_regulation_of_chromosome_organization GO:2001252 12133 49 45 2 847 6 3 false 0.04236753547875974 0.04236753547875974 8.5635846172251E-81 ribosome_assembly GO:0042255 12133 16 45 2 417 9 3 false 0.042498308573086584 0.042498308573086584 3.349634512578164E-29 histone_H3-K27_acetylation GO:0043974 12133 2 45 1 47 1 1 false 0.04255319148936153 0.04255319148936153 9.250693802035048E-4 RNA-dependent_ATPase_activity GO:0008186 12133 21 45 2 228 4 1 false 0.043395866376402914 0.043395866376402914 4.020483440001667E-30 RNA_catabolic_process GO:0006401 12133 203 45 5 4368 42 3 false 0.04342239791324415 0.04342239791324415 0.0 cell_part GO:0044464 12133 9983 45 45 10701 45 2 false 0.043626839575912596 0.043626839575912596 0.0 cell_cycle_DNA_replication GO:0044786 12133 11 45 1 989 4 2 false 0.04381803484051147 0.04381803484051147 4.766880938994118E-26 cell GO:0005623 12133 9984 45 45 10701 45 1 false 0.0438243652609677 0.0438243652609677 0.0 negative_regulation_of_metabolic_process GO:0009892 12133 1354 45 12 8327 44 3 false 0.043990509341968784 0.043990509341968784 0.0 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 45 6 2807 7 3 false 0.04480625875933395 0.04480625875933395 0.0 rRNA_transport GO:0051029 12133 8 45 1 2392 14 2 false 0.045940616161778 0.045940616161778 3.806450242643356E-23 RNA_phosphodiester_bond_hydrolysis GO:0090501 12133 4 45 1 3418 40 2 false 0.04601551038238064 0.04601551038238064 1.7615121152244582E-13 intracellular_receptor_signaling_pathway GO:0030522 12133 217 45 2 3547 6 1 false 0.0474532274410358 0.0474532274410358 0.0 hormone_receptor_binding GO:0051427 12133 122 45 2 918 3 1 false 0.04801370752195857 0.04801370752195857 1.5301276126382055E-155 Leydig_cell_differentiation GO:0033327 12133 10 45 1 2446 12 4 false 0.04807722396091816 0.04807722396091816 4.821684083574537E-28 cellular_glucose_homeostasis GO:0001678 12133 56 45 2 571 4 2 false 0.049846086512974695 0.049846086512974695 4.9142508899008383E-79 negative_regulation_of_transcription_regulatory_region_DNA_binding GO:2000678 12133 10 45 1 1177 6 3 false 0.0500105484272407 0.0500105484272407 7.390052951321887E-25 cellular_macromolecular_complex_assembly GO:0034622 12133 517 45 9 973 11 1 false 0.05002808375152391 0.05002808375152391 3.312522477266262E-291 positive_regulation_of_protein_autophosphorylation GO:0031954 12133 11 45 1 648 3 3 false 0.0501424726366448 0.0501424726366448 5.139167705065388E-24 regulation_of_biological_quality GO:0065008 12133 2082 45 13 6908 28 1 false 0.050480123632862264 0.050480123632862264 0.0 production_of_molecular_mediator_involved_in_inflammatory_response GO:0002532 12133 18 45 1 4184 12 2 false 0.05048589031859362 0.05048589031859362 4.3012458861645E-50 nitrogen_compound_transport GO:0071705 12133 428 45 5 2783 14 1 false 0.05087747322552694 0.05087747322552694 0.0 ephrin_receptor_signaling_pathway GO:0048013 12133 30 45 1 586 1 1 false 0.05119453924913826 0.05119453924913826 5.184030943639595E-51 regulation_of_transmembrane_transporter_activity GO:0022898 12133 78 45 2 563 3 3 false 0.05180276569455496 0.05180276569455496 8.813007984613145E-98 regulation_of_respiratory_burst GO:0060263 12133 9 45 1 4476 27 2 false 0.05304416180894752 0.05304416180894752 5.072797550268562E-28 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 45 5 2556 6 1 false 0.05323829826648905 0.05323829826648905 0.0 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 45 4 2776 7 3 false 0.05375971122432485 0.05375971122432485 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 45 24 7980 45 1 false 0.054068469024378625 0.054068469024378625 0.0 regulation_of_glutamate_receptor_signaling_pathway GO:1900449 12133 18 45 1 1626 5 2 false 0.05420380687243483 0.05420380687243483 1.1147667968820106E-42 negative_regulation_of_RNA_splicing GO:0033119 12133 15 45 2 1037 27 3 false 0.055653675312422816 0.055653675312422816 8.39457188486895E-34 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 45 24 7958 45 2 false 0.0557970278603452 0.0557970278603452 0.0 microtubule_organizing_center GO:0005815 12133 413 45 3 1076 3 2 false 0.05629425455675659 0.05629425455675659 2.6476518998275E-310 telomere_cap_complex GO:0000782 12133 10 45 1 519 3 3 false 0.056804341025211105 0.056804341025211105 2.7923954404854774E-21 RNA_export_from_nucleus GO:0006405 12133 72 45 5 165 6 2 false 0.05700994684236248 0.05700994684236248 1.3059643179360761E-48 ribosomal_small_subunit_assembly GO:0000028 12133 6 45 2 128 9 3 false 0.05711463166828633 0.05711463166828633 1.8437899825856603E-10 circulatory_system_process GO:0003013 12133 307 45 2 1272 2 1 false 0.058106824221044205 0.058106824221044205 1.974873217376429E-304 telomere_maintenance GO:0000723 12133 61 45 2 888 6 3 false 0.05820485741061766 0.05820485741061766 5.866244325488287E-96 negative_regulation_of_DNA_metabolic_process GO:0051053 12133 58 45 2 1888 13 4 false 0.058231504357619694 0.058231504357619694 5.587452620659773E-112 regulation_of_mitotic_recombination GO:0000019 12133 4 45 1 68 1 2 false 0.05882352941176431 0.05882352941176431 1.2279204553129108E-6 replicative_cell_aging GO:0001302 12133 4 45 1 68 1 1 false 0.05882352941176431 0.05882352941176431 1.2279204553129108E-6 innate_immune_response GO:0045087 12133 626 45 4 1268 4 2 false 0.05911625138782176 0.05911625138782176 0.0 histone_acetylation GO:0016573 12133 121 45 3 309 3 2 false 0.05913791467694063 0.05913791467694063 3.1224257129978892E-89 regulation_of_ion_transmembrane_transporter_activity GO:0032412 12133 73 45 2 485 3 3 false 0.060589408554015886 0.060589408554015886 1.1784649326580688E-88 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 45 20 307 24 1 false 0.06124236356772187 0.06124236356772187 1.4733469150792184E-83 regulation_of_metabolic_process GO:0019222 12133 4469 45 27 9189 44 2 false 0.06125449268870323 0.06125449268870323 0.0 response_to_extracellular_stimulus GO:0009991 12133 260 45 2 1046 2 1 false 0.061606301517776976 0.061606301517776976 6.4524154237794786E-254 sex_determination GO:0007530 12133 21 45 1 340 1 1 false 0.0617647058823462 0.0617647058823462 6.623492102010024E-34 energy_homeostasis GO:0097009 12133 8 45 1 128 1 1 false 0.0624999999999992 0.0624999999999992 6.994461389025716E-13 RNA_polymerase_II_core_binding GO:0000993 12133 8 45 1 373 3 3 false 0.06313893208493673 0.06313893208493673 1.1605711850361222E-16 mRNA_cis_splicing,_via_spliceosome GO:0045292 12133 10 45 3 202 20 1 false 0.0636627699086899 0.0636627699086899 4.0230126285336683E-17 respiratory_burst GO:0045730 12133 21 45 1 2877 9 1 false 0.06389399033365326 0.06389399033365326 1.2658513282149024E-53 telomeric_loop_formation GO:0031627 12133 2 45 1 61 2 1 false 0.06502732240437312 0.06502732240437312 5.464480874317068E-4 regulation_of_histone_modification GO:0031056 12133 77 45 2 1240 7 3 false 0.06521879633886025 0.06521879633886025 1.0351200557646026E-124 positive_regulation_of_telomere_maintenance GO:0032206 12133 5 45 1 225 3 5 false 0.06548152893444568 0.06548152893444568 2.1762089818012272E-10 positive_regulation_of_sodium_ion_transport GO:0010765 12133 11 45 1 166 1 3 false 0.06626506024096748 0.06626506024096748 2.123209741249517E-17 multivesicular_body_sorting_pathway GO:0071985 12133 17 45 1 2490 10 2 false 0.06632957835583483 0.06632957835583483 6.909596477174519E-44 telomere_organization GO:0032200 12133 62 45 2 689 5 1 false 0.06672627208199454 0.06672627208199454 5.719891778584196E-90 ligand-dependent_nuclear_receptor_binding GO:0016922 12133 21 45 1 918 3 1 false 0.06714101799035216 0.06714101799035216 3.879215472117617E-43 positive_regulation_of_organelle_organization GO:0010638 12133 217 45 3 2191 10 3 false 0.06811828032523704 0.06811828032523704 1.6765812392172608E-306 chromatin_binding GO:0003682 12133 309 45 4 8962 45 1 false 0.06842069522732569 0.06842069522732569 0.0 protein_binding GO:0005515 12133 6397 45 37 8962 45 1 false 0.06930622957087063 0.06930622957087063 0.0 regulation_of_telomere_maintenance_via_semi-conservative_replication GO:0032213 12133 2 45 1 57 2 3 false 0.06954887218045179 0.06954887218045179 6.265664160401061E-4 glutamate_receptor_signaling_pathway GO:0007215 12133 47 45 1 1975 3 1 false 0.06974140040643054 0.06974140040643054 5.762476809327894E-96 sodium_channel_inhibitor_activity GO:0019871 12133 3 45 1 43 1 3 false 0.06976744186046464 0.06976744186046464 8.103071063933269E-5 regulation_of_protein_autophosphorylation GO:0031952 12133 21 45 1 870 3 2 false 0.0707593528674328 0.0707593528674328 1.2136753132364896E-42 cellular_macromolecule_localization GO:0070727 12133 918 45 8 2206 12 2 false 0.07155477315634315 0.07155477315634315 0.0 glutamate_receptor_activity GO:0008066 12133 39 45 1 545 1 2 false 0.07155963302752853 0.07155963302752853 1.566822417867833E-60 vacuolar_protein_catabolic_process GO:0007039 12133 10 45 1 409 3 1 false 0.07174222782591703 0.07174222782591703 3.095189671373722E-20 U2_snRNP GO:0005686 12133 5 45 2 93 9 1 false 0.07184271360012436 0.07184271360012436 1.9241395291318295E-8 translation GO:0006412 12133 457 45 7 5433 44 3 false 0.07215357457941876 0.07215357457941876 0.0 protein_localization_to_organelle GO:0033365 12133 516 45 7 914 8 1 false 0.07310534987478283 0.07310534987478283 5.634955900168089E-271 positive_regulation_of_actin_cytoskeleton_reorganization GO:2000251 12133 10 45 1 134 1 3 false 0.07462686567164051 0.07462686567164051 2.742420554791422E-15 regulation_of_gene_silencing GO:0060968 12133 19 45 1 6310 26 2 false 0.07555573120528596 0.07555573120528596 7.876216148484232E-56 lipid_oxidation GO:0034440 12133 63 45 1 829 1 2 false 0.07599517490952237 0.07599517490952237 3.0071957971693384E-96 excretion GO:0007588 12133 50 45 1 1272 2 1 false 0.07710093077804782 0.07710093077804782 4.8139348402185623E-91 ubiquitin-dependent_protein_catabolic_process_via_the_multivesicular_body_sorting_pathway GO:0043162 12133 10 45 1 379 3 3 false 0.0772843448669261 0.0772843448669261 6.689174917849262E-20 regulation_of_chromatin_silencing GO:0031935 12133 12 45 1 2529 17 3 false 0.07791123139076009 0.07791123139076009 7.182938226109868E-33 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 45 6 723 6 2 false 0.07853739610101801 0.07853739610101801 2.0953844092707462E-201 structural_molecule_activity GO:0005198 12133 526 45 5 10257 45 1 false 0.07893193506499518 0.07893193506499518 0.0 negative_regulation_of_innate_immune_response GO:0045824 12133 14 45 1 685 4 4 false 0.0794483695190343 0.0794483695190343 1.989838073929195E-29 deacetylase_activity GO:0019213 12133 35 45 1 2556 6 1 false 0.07947297801360549 0.07947297801360549 7.098365746650995E-80 nucleoside_phosphate_binding GO:1901265 12133 1998 45 21 4407 36 2 false 0.08033670889997305 0.08033670889997305 0.0 water_homeostasis GO:0030104 12133 14 45 1 677 4 1 false 0.08035994471001838 0.08035994471001838 2.3492827505763342E-29 nuclear_telomere_cap_complex GO:0000783 12133 10 45 1 244 2 3 false 0.08044930176076072 0.08044930176076072 5.8481730272741835E-18 response_to_activity GO:0014823 12133 29 45 1 5200 15 1 false 0.08057006479424235 0.08057006479424235 1.6459337475648036E-77 nucleolus_organization GO:0007000 12133 5 45 1 62 1 1 false 0.08064516129032337 0.08064516129032337 1.545355726980193E-7 peptidyl-lysine_modification GO:0018205 12133 185 45 3 623 4 1 false 0.08074867223236055 0.08074867223236055 7.634244791194444E-164 cellular_macromolecule_catabolic_process GO:0044265 12133 672 45 8 6457 44 3 false 0.08103508915065602 0.08103508915065602 0.0 ATP_catabolic_process GO:0006200 12133 318 45 4 1012 6 4 false 0.0817245312892031 0.0817245312892031 1.0026310858617265E-272 cellular_response_to_oxidative_stress GO:0034599 12133 95 45 2 2340 12 3 false 0.08262335812528548 0.08262335812528548 6.007102514115277E-172 regulation_of_Rac_protein_signal_transduction GO:0035020 12133 23 45 1 278 1 2 false 0.08273381294964618 0.08273381294964618 4.034778444759645E-34 negative_regulation_of_histone_H3-K27_acetylation GO:1901675 12133 1 45 1 12 1 3 false 0.08333333333333322 0.08333333333333322 0.08333333333333322 Sin3-type_complex GO:0070822 12133 12 45 1 280 2 3 false 0.0840245775729564 0.0840245775729564 2.6196359374220302E-21 rRNA_3'-end_processing GO:0031125 12133 3 45 1 105 3 2 false 0.08407126853728226 0.08407126853728226 5.334471353888465E-6 rRNA_processing GO:0006364 12133 102 45 3 231 3 3 false 0.08467325346002468 0.08467325346002468 2.6685808966337758E-68 negative_regulation_of_protein_acetylation GO:1901984 12133 13 45 1 447 3 3 false 0.08492017626114272 0.08492017626114272 2.610849740119753E-25 RNA_polymerase_binding GO:0070063 12133 15 45 1 1005 6 1 false 0.08648386541722936 0.08648386541722936 1.3477288899053611E-33 interleukin-1_binding GO:0019966 12133 9 45 1 201 2 2 false 0.08776119402984126 0.08776119402984126 8.126485509638212E-16 regulation_of_transcription_regulatory_region_DNA_binding GO:2000677 12133 18 45 1 1186 6 2 false 0.08785473274154279 0.08785473274154279 3.3815858455495472E-40 translation_regulator_activity GO:0045182 12133 21 45 1 10260 45 2 false 0.08825791292541135 0.08825791292541135 3.0418957762761004E-65 regulation_of_histone_acetylation GO:0035065 12133 31 45 2 166 3 3 false 0.08985387225176907 0.08985387225176907 2.4571391045681945E-34 basal_RNA_polymerase_II_transcription_machinery_binding GO:0001099 12133 76 45 3 464 7 1 false 0.09025020934538645 0.09025020934538645 2.7883330382309735E-89 preribosome GO:0030684 12133 14 45 2 569 21 1 false 0.09039784395299143 0.09039784395299143 2.7469396354391632E-28 Rac_protein_signal_transduction GO:0016601 12133 33 45 1 365 1 1 false 0.0904109589041143 0.0904109589041143 1.0734561739608448E-47 telomeric_DNA_binding GO:0042162 12133 16 45 1 1189 7 1 false 0.09069811792461757 0.09069811792461757 1.4512187070438412E-36 mRNA_5'-splice_site_recognition GO:0000395 12133 3 45 2 25 5 2 false 0.09130434782608648 0.09130434782608648 4.347826086956512E-4 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 45 1 1014 1 1 false 0.09171597633136892 0.09171597633136892 2.468210871514413E-134 ephrin_receptor_binding GO:0046875 12133 29 45 1 918 3 1 false 0.09190589577385679 0.09190589577385679 1.6526990639165767E-55 positive_regulation_of_transporter_activity GO:0032411 12133 34 45 1 2101 6 4 false 0.0933587942700212 0.0933587942700212 4.2098203958278254E-75 positive_regulation_of_fatty_acid_metabolic_process GO:0045923 12133 21 45 1 1935 9 4 false 0.09372549246542754 0.09372549246542754 5.436803324891044E-50 sarcoplasmic_reticulum GO:0016529 12133 42 45 1 858 2 2 false 0.09556021574693375 0.09556021574693375 2.4222927576820215E-72 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_oxidative_stress GO:0043619 12133 6 45 1 122 2 2 false 0.09632841078444868 0.09632841078444868 2.4739517141595845E-10 negative_regulation_of_telomere_maintenance_via_semi-conservative_replication GO:0032214 12133 2 45 1 41 2 4 false 0.09634146341463547 0.09634146341463547 0.001219512195121968 telomere_maintenance_via_telomere_shortening GO:0010834 12133 3 45 1 61 2 1 false 0.0967213114754121 0.0967213114754121 2.7785495971103487E-5 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 45 11 7606 44 4 false 0.09803381375314549 0.09803381375314549 0.0 regulation_of_telomere_maintenance GO:0032204 12133 13 45 1 511 4 4 false 0.09822116918278304 0.09822116918278304 4.483811812406489E-26 histone_modification GO:0016570 12133 306 45 3 2375 9 2 false 0.09842440534828822 0.09842440534828822 0.0 prespliceosome GO:0071010 12133 1 45 1 150 15 1 false 0.10000000000000095 0.10000000000000095 0.006666666666666822 negative_regulation_of_homeostatic_process GO:0032845 12133 24 45 1 3207 14 3 false 0.10001696937550118 0.10001696937550118 4.828346180922529E-61 regulation_of_mRNA_processing GO:0050684 12133 49 45 2 3175 35 3 false 0.1006410926863239 0.1006410926863239 2.292701139367024E-109 aging GO:0007568 12133 170 45 2 2776 9 1 false 0.10106785712452258 0.10106785712452258 5.943091023043611E-277 cytoplasmic_stress_granule GO:0010494 12133 29 45 1 5117 19 2 false 0.10253172350264572 0.10253172350264572 2.627932865737447E-77 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 45 4 3702 11 3 false 0.1061681402833372 0.1061681402833372 0.0 regulation_of_potassium_ion_transmembrane_transport GO:1901379 12133 12 45 1 216 2 3 false 0.10826873385011943 0.10826873385011943 6.338882729411382E-20 viral_genome_expression GO:0019080 12133 153 45 5 557 10 2 false 0.10831563950520157 0.10831563950520157 1.6461772406083414E-141 Cul5-RING_ubiquitin_ligase_complex GO:0031466 12133 5 45 1 90 2 1 false 0.10861423220973858 0.10861423220973858 2.2753507521444733E-8 negative_regulation_of_translation GO:0017148 12133 61 45 2 1470 14 4 false 0.11195074549726211 0.11195074549726211 1.1152524521517982E-109 regulation_of_RNA_splicing GO:0043484 12133 52 45 2 3151 35 3 false 0.11262154094111529 0.11262154094111529 1.4828410310444421E-114 cleavage_involved_in_rRNA_processing GO:0000469 12133 4 45 1 102 3 2 false 0.11417588817705338 0.11417588817705338 2.353176494119972E-7 regulation_of_potassium_ion_transmembrane_transporter_activity GO:1901016 12133 9 45 1 153 2 3 false 0.11455108359131388 0.11455108359131388 1.0038611131963863E-14 laminin_binding GO:0043236 12133 21 45 1 6400 37 2 false 0.11480715906994349 0.11480715906994349 6.206260279857665E-61 regulation_of_gluconeogenesis GO:0006111 12133 17 45 1 3082 22 5 false 0.11494310788142661 0.11494310788142661 1.8201711110678968E-45 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 45 1 695 1 3 false 0.11510791366907402 0.11510791366907402 3.5521820546065696E-107 manganese_ion_binding GO:0030145 12133 30 45 1 1457 6 1 false 0.11754556216850202 0.11754556216850202 4.4711575218911957E-63 cellular_component GO:0005575 12133 10701 45 45 11221 45 1 false 0.11770883813810341 0.11770883813810341 0.0 positive_regulation_of_protein_acetylation GO:1901985 12133 17 45 1 823 6 3 false 0.11805087664834522 0.11805087664834522 1.1521858928998402E-35 chromosome_organization_involved_in_meiosis GO:0070192 12133 18 45 1 1696 12 4 false 0.12054994395943286 0.12054994395943286 5.199839023113478E-43 double-stranded_telomeric_DNA_binding GO:0003691 12133 5 45 1 120 3 2 false 0.12083392679105748 0.12083392679105748 5.247194713279229E-9 regulation_of_actin_cytoskeleton_organization GO:0032956 12133 166 45 2 476 2 3 false 0.12114108801419537 0.12114108801419537 5.437988564533384E-133 lamellipodium GO:0030027 12133 121 45 1 990 1 2 false 0.1222222222222129 0.1222222222222129 5.739208350847419E-159 SH2_domain_binding GO:0042169 12133 31 45 1 486 2 1 false 0.12362649017858361 0.12362649017858361 1.1318841086292139E-49 carbohydrate_homeostasis GO:0033500 12133 109 45 2 677 4 1 false 0.12363934904891102 0.12363934904891102 4.176760407078775E-129 regulation_of_ion_transport GO:0043269 12133 307 45 2 1393 3 2 false 0.12409610274007385 0.12409610274007385 3.368915E-318 regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033143 12133 43 45 1 1642 5 2 false 0.12440092037783716 0.12440092037783716 5.767987369966462E-86 regulation_of_protein_stability GO:0031647 12133 99 45 2 2240 14 2 false 0.12466957057693781 0.12466957057693781 1.7785498552391114E-175 H4_histone_acetyltransferase_activity GO:0010485 12133 10 45 1 80 1 2 false 0.12500000000000064 0.12500000000000064 6.073518323310398E-13 regulation_of_histone_H3-K27_acetylation GO:1901674 12133 2 45 1 31 2 2 false 0.1268817204301071 0.1268817204301071 0.002150537634408595 germ_cell_nucleus GO:0043073 12133 15 45 1 4764 43 1 false 0.12733742285428212 0.12733742285428212 9.047009090366007E-44 activation_of_MAPKK_activity GO:0000186 12133 64 45 1 496 1 3 false 0.12903225806453644 0.12903225806453644 2.7437381948522894E-82 cis_assembly_of_pre-catalytic_spliceosome GO:0000354 12133 2 45 1 120 8 3 false 0.12941176470588361 0.12941176470588361 1.4005602240896732E-4 negative_regulation_of_inflammatory_response GO:0050728 12133 56 45 1 432 1 4 false 0.12962962962960567 0.12962962962960567 7.653768457766755E-72 immune_effector_process GO:0002252 12133 445 45 3 1618 5 1 false 0.1313227649376348 0.1313227649376348 0.0 muscle_structure_development GO:0061061 12133 413 45 3 3152 10 2 false 0.13283050623824388 0.13283050623824388 0.0 telomere_maintenance_via_telomerase GO:0007004 12133 16 45 2 43 2 3 false 0.13289036544850544 0.13289036544850544 3.770992892805634E-12 MLL5-L_complex GO:0070688 12133 8 45 1 60 1 1 false 0.13333333333333472 0.13333333333333472 3.9083555578552816E-10 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 45 5 174 5 1 false 0.13358452669951057 0.13358452669951057 2.5039480990851377E-47 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 45 29 5597 43 2 false 0.13360191538915434 0.13360191538915434 0.0 regulation_of_potassium_ion_transport GO:0043266 12133 32 45 1 238 1 2 false 0.13445378151259108 0.13445378151259108 2.0777607490676014E-40 positive_regulation_of_kinase_activity GO:0033674 12133 438 45 2 1181 2 3 false 0.13734841200357736 0.13734841200357736 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 45 29 5588 43 2 false 0.1378506799048202 0.1378506799048202 0.0 regulation_of_tight_junction_assembly GO:2000810 12133 8 45 1 58 1 2 false 0.13793103448276028 0.13793103448276028 5.217035699399583E-10 electron_transport_chain GO:0022900 12133 109 45 1 788 1 2 false 0.1383248730963905 0.1383248730963905 6.953764732633874E-137 positive_regulation_of_fatty_acid_oxidation GO:0046321 12133 10 45 1 72 1 3 false 0.13888888888888892 0.13888888888888892 1.8649342542466167E-12 histone_pre-mRNA_DCP_binding GO:0071208 12133 4 45 1 763 28 1 false 0.1391634538424584 0.1391634538424584 7.13729230310747E-11 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 45 29 5686 43 2 false 0.14047294940902633 0.14047294940902633 0.0 regulation_of_DNA_replication GO:0006275 12133 92 45 2 2913 21 3 false 0.14076475912678382 0.14076475912678382 1.0142928746758388E-176 sister_chromatid_cohesion GO:0007062 12133 31 45 1 1441 7 3 false 0.14148804199609755 0.14148804199609755 1.3727179636790552E-64 MAP_kinase_kinase_activity GO:0004708 12133 74 45 1 521 1 3 false 0.14203454894434142 0.14203454894434142 6.903948166738437E-92 protein_localization_to_chromosome,_telomeric_region GO:0070198 12133 6 45 1 42 1 1 false 0.14285714285714374 0.14285714285714374 1.9062920218247967E-7 positive_regulation_of_leukocyte_differentiation GO:1902107 12133 89 45 1 613 1 3 false 0.1451876019576035 0.1451876019576035 1.1276416375337016E-109 positive_regulation_of_cation_channel_activity GO:2001259 12133 17 45 1 224 2 3 false 0.14634048686738452 0.14634048686738452 7.366387194248368E-26 negative_regulation_of_ion_transport GO:0043271 12133 50 45 1 974 3 3 false 0.146376168515357 0.146376168515357 4.081641839466338E-85 viral_latency GO:0019042 12133 11 45 1 355 5 1 false 0.146397134559191 0.146397134559191 4.136206699450328E-21 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 45 29 5629 43 2 false 0.14697225664389163 0.14697225664389163 0.0 regulation_of_N-methyl-D-aspartate_selective_glutamate_receptor_activity GO:2000310 12133 11 45 1 144 2 4 false 0.14743589743588256 0.14743589743588256 1.0696206202759193E-16 DNA_repair GO:0006281 12133 368 45 4 977 6 2 false 0.1478110639300022 0.1478110639300022 3.284245924949814E-280 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 45 4 768 4 1 false 0.14809844354772278 0.14809844354772278 1.6461815804374103E-220 negative_regulation_of_immune_response GO:0050777 12133 48 45 1 1512 5 4 false 0.14915184182303287 0.14915184182303287 6.35137019676024E-92 macromolecule_catabolic_process GO:0009057 12133 820 45 8 6846 44 2 false 0.1492549360053967 0.1492549360053967 0.0 Set1C/COMPASS_complex GO:0048188 12133 9 45 1 60 1 1 false 0.1500000000000016 0.1500000000000016 6.764461542441828E-11 cytosol GO:0005829 12133 2226 45 11 5117 19 1 false 0.15020564648152931 0.15020564648152931 0.0 sarcoplasm GO:0016528 12133 47 45 1 6938 24 1 false 0.15075538244649697 0.15075538244649697 8.759395869796841E-122 cellular_homeostasis GO:0019725 12133 585 45 4 7566 27 2 false 0.1515387893991458 0.1515387893991458 0.0 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 45 3 742 3 2 false 0.152626152129731 0.152626152129731 9.121396596563632E-222 in_utero_embryonic_development GO:0001701 12133 295 45 4 471 4 1 false 0.15271523237654053 0.15271523237654053 1.719393530200133E-134 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 45 24 8688 44 3 false 0.15305052677070485 0.15305052677070485 0.0 DNA_recombination GO:0006310 12133 190 45 3 791 6 1 false 0.15347109068455161 0.15347109068455161 1.2250789605162758E-188 chromosome_organization GO:0051276 12133 689 45 5 2031 9 1 false 0.15357872470798506 0.15357872470798506 0.0 rRNA_export_from_nucleus GO:0006407 12133 5 45 1 214 7 3 false 0.15455249958594583 0.15455249958594583 2.8025299229048785E-10 negative_regulation_of_organelle_organization GO:0010639 12133 168 45 2 2125 9 3 false 0.15502586850936975 0.15502586850936975 2.2467097914760192E-254 positive_regulation_of_phosphorylation GO:0042327 12133 563 45 3 1487 4 3 false 0.15513831081328724 0.15513831081328724 0.0 positive_regulation_of_glucose_metabolic_process GO:0010907 12133 30 45 1 192 1 3 false 0.15625000000000785 0.15625000000000785 9.188249429629057E-36 DNA_polymerase_activity GO:0034061 12133 49 45 2 123 2 1 false 0.15673730507796635 0.15673730507796635 1.6565752525035403E-35 regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014066 12133 54 45 1 1607 5 2 false 0.157279137222033 0.157279137222033 4.2614304493416375E-102 mRNA_5'-UTR_binding GO:0048027 12133 5 45 1 91 3 1 false 0.15759147219821418 0.15759147219821418 2.1503314800486076E-8 telomere_capping GO:0016233 12133 5 45 1 61 2 1 false 0.1584699453551949 0.1584699453551949 1.6809132468907094E-7 positive_regulation_of_phosphatidylinositol_3-kinase_cascade GO:0014068 12133 45 45 1 798 3 3 false 0.16000157199610768 0.16000157199610768 1.088358768929943E-74 ubiquitin_ligase_complex GO:0000151 12133 147 45 2 9248 45 2 false 0.16006653429060894 0.16006653429060894 0.0 regulation_of_transmembrane_transport GO:0034762 12133 183 45 2 6614 26 3 false 0.16093358524385226 0.16093358524385226 0.0 regulation_of_peptidyl-lysine_acetylation GO:2000756 12133 33 45 2 128 3 2 false 0.16291713535808267 0.16291713535808267 2.3260819461485724E-31 cellular_monovalent_inorganic_cation_homeostasis GO:0030004 12133 26 45 1 306 2 2 false 0.1629701060752021 0.1629701060752021 2.8281153145438213E-38 positive_regulation_of_immune_response GO:0050778 12133 394 45 3 1600 6 4 false 0.1631704304749873 0.1631704304749873 0.0 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 45 4 5027 23 3 false 0.16392735714639806 0.16392735714639806 0.0 negative_regulation_of_systemic_arterial_blood_pressure GO:0003085 12133 11 45 1 67 1 2 false 0.16417910447761364 0.16417910447761364 7.781717560880856E-13 regulation_of_biosynthetic_process GO:0009889 12133 3012 45 22 5483 34 2 false 0.16466740336184799 0.16466740336184799 0.0 extracellular_matrix_binding GO:0050840 12133 36 45 1 8962 45 1 false 0.1660436943352891 0.1660436943352891 2.063133026894305E-101 regulation_of_actin_cytoskeleton_reorganization GO:2000249 12133 17 45 1 196 2 2 false 0.16635269492412802 0.16635269492412802 7.814357632608707E-25 sodium_ion_homeostasis GO:0055078 12133 26 45 1 299 2 2 false 0.16661803326525756 0.16661803326525756 5.299686091705976E-38 regulation_of_granulocyte_differentiation GO:0030852 12133 13 45 1 78 1 2 false 0.1666666666666632 0.1666666666666632 4.535236363334804E-15 positive_regulation_of_metabolic_process GO:0009893 12133 1872 45 13 8366 44 3 false 0.16691047012538252 0.16691047012538252 0.0 negative_regulation_of_histone_modification GO:0031057 12133 27 45 1 606 4 4 false 0.16704325531538364 0.16704325531538364 1.4639212349007274E-47 positive_regulation_of_ion_transmembrane_transporter_activity GO:0032414 12133 28 45 1 473 3 3 false 0.1676180370698185 0.1676180370698185 8.750359231366189E-46 positive_regulation_of_cellular_carbohydrate_metabolic_process GO:0010676 12133 39 45 1 1899 9 4 false 0.17068663554821942 0.17068663554821942 4.146985053845577E-82 DNA-directed_RNA_polymerase_II,_core_complex GO:0005665 12133 15 45 1 809 10 3 false 0.1715624086619244 0.1715624086619244 3.580788070603621E-32 negative_regulation_of_telomere_maintenance GO:0032205 12133 9 45 1 149 3 5 false 0.17156850042755914 0.17156850042755914 1.2825398549514826E-14 myeloid_cell_differentiation GO:0030099 12133 237 45 2 2177 7 2 false 0.17188437285088434 0.17188437285088434 0.0 regulation_of_sodium_ion_transport GO:0002028 12133 37 45 1 215 1 2 false 0.17209302325580766 0.17209302325580766 1.8499074186131244E-42 regulation_of_protein_localization_to_nucleus GO:1900180 12133 125 45 1 722 1 3 false 0.17313019390583745 0.17313019390583745 8.18717732691146E-144 passive_transmembrane_transporter_activity GO:0022803 12133 304 45 3 544 3 1 false 0.17375013041648396 0.17375013041648396 2.1953421087848878E-161 respiratory_burst_involved_in_inflammatory_response GO:0002536 12133 4 45 1 23 1 2 false 0.1739130434782608 0.1739130434782608 1.1293054771315566E-4 positive_regulation_of_transferase_activity GO:0051347 12133 445 45 2 2275 4 3 false 0.17394777597298464 0.17394777597298464 0.0 regulation_of_ion_transmembrane_transport GO:0034765 12133 176 45 2 662 3 3 false 0.17404737854849717 0.17404737854849717 9.171243521861199E-166 double-strand_break_repair_via_nonhomologous_end_joining GO:0006303 12133 19 45 1 109 1 2 false 0.17431192660550582 0.17431192660550582 1.2517149851754563E-21 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 45 5 145 5 1 false 0.17571950695084984 0.17571950695084984 1.7288474062512548E-37 positive_regulation_of_granulocyte_differentiation GO:0030854 12133 9 45 1 51 1 3 false 0.17647058823529416 0.17647058823529416 3.2869734759482606E-10 single-stranded_RNA_binding GO:0003727 12133 40 45 3 763 28 1 false 0.17665380449382267 0.17665380449382267 1.1547828689277465E-67 cellular_response_to_carbohydrate_stimulus GO:0071322 12133 54 45 1 1414 5 3 false 0.17714127621611675 0.17714127621611675 4.832993554429222E-99 embryo_development GO:0009790 12133 768 45 4 3347 10 3 false 0.17795481242557085 0.17795481242557085 0.0 RNA-directed_DNA_polymerase_activity GO:0003964 12133 21 45 2 49 2 1 false 0.17857142857142932 0.17857142857142932 2.560824792650333E-14 sodium_channel_regulator_activity GO:0017080 12133 14 45 1 78 1 2 false 0.17948717948717585 0.17948717948717585 9.768201397951623E-16 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 45 7 4597 14 2 false 0.18092569636601086 0.18092569636601086 0.0 cellular_senescence GO:0090398 12133 32 45 1 1140 7 2 false 0.18113479612139693 0.18113479612139693 6.165063165267623E-63 regulation_of_cell_junction_assembly GO:1901888 12133 35 45 1 1245 7 3 false 0.18134769701939218 0.18134769701939218 7.812749785355693E-69 negative_regulation_of_DNA_binding GO:0043392 12133 35 45 1 2119 12 3 false 0.1815859357097767 0.1815859357097767 5.275494739019896E-77 regulation_of_protein_catabolic_process GO:0042176 12133 150 45 2 1912 10 3 false 0.1818948218127262 0.1818948218127262 1.3832082048306078E-227 regulation_of_muscle_organ_development GO:0048634 12133 106 45 1 1105 2 2 false 0.1827316545347932 0.1827316545347932 5.2870889259577626E-151 deoxyribonuclease_activity GO:0004536 12133 36 45 1 197 1 1 false 0.18274111675125865 0.18274111675125865 2.8214794282741635E-40 substrate-specific_channel_activity GO:0022838 12133 291 45 3 512 3 2 false 0.18277962940308515 0.18277962940308515 2.547694139879492E-151 growth_factor_binding GO:0019838 12133 135 45 2 6397 37 1 false 0.18322530329667455 0.18322530329667455 1.7435678435075742E-283 regulation_of_fatty_acid_oxidation GO:0046320 12133 18 45 1 98 1 2 false 0.18367346938775092 0.18367346938775092 4.860716398592285E-20 regulation_of_actin_filament-based_process GO:0032970 12133 192 45 2 6365 26 2 false 0.18416125475387993 0.18416125475387993 0.0 DNA_endoreduplication GO:0042023 12133 7 45 1 38 1 2 false 0.18421052631579016 0.18421052631579016 7.923769533676653E-8 U1_snRNP GO:0005685 12133 2 45 1 93 9 1 false 0.185133239831703 0.185133239831703 2.337540906965817E-4 channel_inhibitor_activity GO:0016248 12133 20 45 1 304 3 2 false 0.18523806894453362 0.18523806894453362 1.0141079171115058E-31 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 45 3 1350 4 4 false 0.18749775817510592 0.18749775817510592 0.0 granulocyte_differentiation GO:0030851 12133 24 45 1 128 1 1 false 0.18749999999999817 0.18749999999999817 1.6570718546380516E-26 ion_transmembrane_transport GO:0034220 12133 556 45 3 970 3 2 false 0.18789129980041192 0.18789129980041192 1.3121997139332702E-286 positive_regulation_of_myeloid_leukocyte_differentiation GO:0002763 12133 36 45 1 191 1 4 false 0.18848167539267968 0.18848167539267968 9.635399898750637E-40 chromatin_silencing GO:0006342 12133 32 45 1 777 5 3 false 0.1900928404201125 0.1900928404201125 1.6134532448312596E-57 peptidyl-amino_acid_modification GO:0018193 12133 623 45 4 2370 9 1 false 0.19020285394171688 0.19020285394171688 0.0 Cul4B-RING_ubiquitin_ligase_complex GO:0031465 12133 4 45 1 21 1 1 false 0.19047619047619052 0.19047619047619052 1.6708437761069314E-4 sodium_channel_activity GO:0005272 12133 26 45 1 256 2 3 false 0.1931678921568402 0.1931678921568402 3.647595212320824E-36 activating_transcription_factor_binding GO:0033613 12133 294 45 4 715 6 1 false 0.19406604035015398 0.19406604035015398 1.6086726333731214E-209 reciprocal_meiotic_recombination GO:0007131 12133 33 45 1 1243 8 4 false 0.1941651749996487 0.1941651749996487 1.0168261018961741E-65 rRNA_metabolic_process GO:0016072 12133 107 45 3 258 4 1 false 0.19479563667378919 0.19479563667378919 1.860360860420455E-75 negative_regulation_of_response_to_external_stimulus GO:0032102 12133 105 45 1 1508 3 3 false 0.1947990951993517 0.1947990951993517 8.164414473234676E-165 temperature_homeostasis GO:0001659 12133 25 45 1 128 1 1 false 0.19531249999999717 0.19531249999999717 3.983345804418197E-27 ion_channel_inhibitor_activity GO:0008200 12133 20 45 1 286 3 2 false 0.19609967497291256 0.19609967497291256 3.5818833657211076E-31 positive_regulation_of_cell_division GO:0051781 12133 51 45 1 3061 13 3 false 0.19656058439359403 0.19656058439359403 3.9220691729316426E-112 digestion GO:0007586 12133 74 45 1 4095 12 1 false 0.19678290413969574 0.19678290413969574 3.1691649898109646E-160 regulation_of_defense_response_to_virus GO:0050688 12133 61 45 1 586 2 5 false 0.19751465826555156 0.19751465826555156 1.8588202781282113E-84 regulation_of_immune_effector_process GO:0002697 12133 188 45 2 891 4 2 false 0.19759313793644598 0.19759313793644598 1.2449327492079068E-198 RNA_stabilization GO:0043489 12133 22 45 3 37 3 1 false 0.19819819819819917 0.19819819819819917 1.0678969112465738E-10 positive_regulation_of_myeloid_cell_differentiation GO:0045639 12133 61 45 1 580 2 3 false 0.1994461318563808 0.1994461318563808 3.6055170484101864E-84 negative_regulation_of_gene_expression,_epigenetic GO:0045814 12133 37 45 1 852 5 2 false 0.1995064819236799 0.1995064819236799 1.1400135698836375E-65 U1_snRNA_binding GO:0030619 12133 1 45 1 15 3 1 false 0.20000000000000015 0.20000000000000015 0.06666666666666664 U12-type_spliceosomal_complex GO:0005689 12133 24 45 4 150 15 1 false 0.2001152362369203 0.2001152362369203 2.5760759444825708E-28 protein_deacylation GO:0035601 12133 58 45 1 2370 9 1 false 0.20018515745939636 0.20018515745939636 8.732809717864973E-118 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 45 1 1881 3 2 false 0.20032645954745992 0.20032645954745992 3.367676499542027E-210 regulation_of_peptidyl-serine_phosphorylation GO:0033135 12133 59 45 1 818 3 2 false 0.20137786697215734 0.20137786697215734 1.6613120232447818E-91 organic_substance_transport GO:0071702 12133 1580 45 10 2783 14 1 false 0.20231012676618865 0.20231012676618865 0.0 positive_regulation_of_inflammatory_response GO:0050729 12133 58 45 1 543 2 4 false 0.20239478637879924 0.20239478637879924 1.3309637222630526E-79 positive_regulation_of_defense_response GO:0031349 12133 229 45 2 1621 6 3 false 0.20298863870833012 0.20298863870833012 6.85443065618377E-286 regulation_of_signal_transduction GO:0009966 12133 1603 45 5 3826 8 4 false 0.20419020946012623 0.20419020946012623 0.0 mRNA_export_from_nucleus GO:0006406 12133 60 45 4 116 5 2 false 0.20430934974991413 0.20430934974991413 1.7435958103584361E-34 spliceosomal_complex_assembly GO:0000245 12133 38 45 5 259 22 2 false 0.20465555363850196 0.20465555363850196 1.791986159229858E-46 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 45 6 1319 6 1 false 0.2057162601404176 0.2057162601404176 6.536050345296563E-309 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 45 22 4972 32 3 false 0.20696776393457808 0.20696776393457808 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 45 3 6813 33 2 false 0.20819136831201845 0.20819136831201845 0.0 RNA_polymerase_II_transcription_corepressor_activity GO:0001106 12133 17 45 1 588 8 5 false 0.21032356264719 0.21032356264719 3.74158836742943E-33 endocytosis GO:0006897 12133 411 45 2 895 2 2 false 0.2106032769674332 0.2106032769674332 2.7872223899360555E-267 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 45 9 4429 32 3 false 0.21402179034961377 0.21402179034961377 0.0 regulation_of_striated_muscle_cell_differentiation GO:0051153 12133 68 45 2 227 3 2 false 0.21432198874639413 0.21432198874639413 1.1311225924750782E-59 small_conjugating_protein_ligase_binding GO:0044389 12133 147 45 2 1005 6 1 false 0.214469897514792 0.214469897514792 6.302468729220369E-181 monocyte_chemotaxis GO:0002548 12133 23 45 1 107 1 1 false 0.21495327102804263 0.21495327102804263 6.985599683738772E-24 signaling_adaptor_activity GO:0035591 12133 65 45 1 839 3 2 false 0.21511447922078772 0.21511447922078772 9.48818477040309E-99 post-embryonic_development GO:0009791 12133 81 45 1 4373 13 3 false 0.2160351461735856 0.2160351461735856 1.5270071764931075E-174 ncRNA_3'-end_processing GO:0043628 12133 8 45 1 270 8 2 false 0.216392470694484 0.216392470694484 1.585153186118045E-15 phosphoprotein_binding GO:0051219 12133 42 45 1 6397 37 1 false 0.2168398431256396 0.2168398431256396 2.265958128878875E-109 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 45 43 7976 45 2 false 0.2170642271904186 0.2170642271904186 0.0 cell_aging GO:0007569 12133 68 45 1 7548 27 2 false 0.21711487458946943 0.21711487458946943 6.81322307999876E-168 negative_regulation_of_defense_response GO:0031348 12133 72 45 1 1505 5 3 false 0.21764625337957635 0.21764625337957635 5.674310231559274E-125 nuclear_chromosome,_telomeric_region GO:0000784 12133 21 45 1 268 3 2 false 0.21788529263792436 0.21788529263792436 1.1663885505356195E-31 non-recombinational_repair GO:0000726 12133 22 45 1 368 4 1 false 0.21934360144187376 0.21934360144187376 7.589243686304588E-36 positive_regulation_of_peptidyl-serine_phosphorylation GO:0033138 12133 47 45 1 594 3 3 false 0.21942681797238892 0.21942681797238892 7.186758669481106E-71 positive_regulation_of_ion_transport GO:0043270 12133 86 45 1 1086 3 3 false 0.21943839699604084 0.21943839699604084 6.3756507891276546E-130 brown_fat_cell_differentiation GO:0050873 12133 27 45 1 123 1 1 false 0.21951219512194683 0.21951219512194683 8.890153945907316E-28 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 45 2 217 2 1 false 0.21979006656423947 0.21979006656423947 1.2933579260360868E-64 ion_channel_activity GO:0005216 12133 286 45 3 473 3 2 false 0.2201431551884613 0.2201431551884613 3.7303800171637374E-137 positive_regulation_of_protein_kinase_B_signaling_cascade GO:0051897 12133 58 45 1 495 2 3 false 0.2208236208237305 0.2208236208237305 3.926574524631079E-77 negative_regulation_of_histone_acetylation GO:0035067 12133 11 45 1 138 3 4 false 0.22206069035040435 0.22206069035040435 1.738355872947967E-16 Ada2/Gcn5/Ada3_transcription_activator_complex GO:0005671 12133 16 45 1 72 1 1 false 0.2222222222222221 0.2222222222222221 2.4293632143762976E-16 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 45 1 676 3 2 false 0.22506803855816837 0.22506803855816837 2.737610529852072E-82 positive_regulation_of_carbohydrate_metabolic_process GO:0045913 12133 44 45 1 2267 13 3 false 0.22545547198965443 0.22545547198965443 9.271079205444775E-94 negative_regulation_of_striated_muscle_cell_differentiation GO:0051154 12133 17 45 1 208 3 3 false 0.22670024677729736 0.22670024677729736 2.72756232006883E-25 transcription_factor_binding GO:0008134 12133 715 45 6 6397 37 1 false 0.22721224276251095 0.22721224276251095 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 45 1 3208 20 2 false 0.22742666513234114 0.22742666513234114 7.591030632914061E-95 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 45 9 4298 32 4 false 0.22747359783170557 0.22747359783170557 0.0 protein_kinase_B_signaling_cascade GO:0043491 12133 98 45 1 806 2 1 false 0.22852519149853287 0.22852519149853287 6.677067387386742E-129 positive_regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033148 12133 8 45 1 35 1 3 false 0.22857142857142917 0.22857142857142917 4.248842827655879E-8 protein_C-terminus_binding GO:0008022 12133 157 45 2 6397 37 1 false 0.22990818286736903 0.22990818286736903 2.34014E-319 single-stranded_DNA_specific_endodeoxyribonuclease_activity GO:0000014 12133 6 45 1 26 1 1 false 0.23076923076923053 0.23076923076923053 4.3434826043521345E-6 regulation_of_protein_complex_assembly GO:0043254 12133 185 45 2 1610 8 3 false 0.2320194100788854 0.2320194100788854 1.34790682725651E-248 regulation_of_protein_kinase_B_signaling_cascade GO:0051896 12133 80 45 1 646 2 2 false 0.23251013991895722 0.23251013991895722 1.7925842553941532E-104 macromolecular_complex_assembly GO:0065003 12133 973 45 11 1603 15 2 false 0.23274837890821698 0.23274837890821698 0.0 regulation_of_receptor_activity GO:0010469 12133 89 45 1 3057 9 3 false 0.23376414586346647 0.23376414586346647 3.874143452259453E-174 response_to_virus GO:0009615 12133 230 45 2 475 2 1 false 0.23393293359989506 0.23393293359989506 3.548520767075247E-142 positive_regulation_of_signal_transduction GO:0009967 12133 782 45 3 3650 8 5 false 0.2350859107756004 0.2350859107756004 0.0 membrane-bounded_organelle GO:0043227 12133 7284 45 43 7980 45 1 false 0.23525326842983135 0.23525326842983135 0.0 protein_export_from_nucleus GO:0006611 12133 46 45 1 2428 14 3 false 0.23548232608273684 0.23548232608273684 1.6048237175829586E-98 actin_cytoskeleton_organization GO:0030036 12133 373 45 2 768 2 2 false 0.2355565514993044 0.2355565514993044 3.0657297438498186E-230 purine_NTP-dependent_helicase_activity GO:0070035 12133 98 45 4 140 4 1 false 0.23564062111150447 0.23564062111150447 9.838676628741767E-37 repressing_transcription_factor_binding GO:0070491 12133 207 45 3 715 6 1 false 0.235810506132139 0.235810506132139 4.3536836236667346E-186 fibroblast_growth_factor_binding GO:0017134 12133 17 45 1 135 2 1 false 0.23681592039799662 0.23681592039799662 6.193063943061966E-22 response_to_DNA_damage_stimulus GO:0006974 12133 570 45 5 1124 7 1 false 0.23768394728372022 0.23768394728372022 0.0 ribonucleoprotein_complex_binding GO:0043021 12133 54 45 1 8962 45 1 false 0.23863080109888138 0.23863080109888138 1.0067816763681274E-142 negative_regulation_of_immune_effector_process GO:0002698 12133 45 45 1 518 3 3 false 0.23905364330890744 0.23905364330890744 6.135357945972138E-66 negative_regulation_of_blood_pressure GO:0045776 12133 28 45 1 117 1 1 false 0.2393162393162351 0.2393162393162351 1.267799191286988E-27 regulation_of_immune_response GO:0050776 12133 533 45 3 2461 8 3 false 0.2404201413786482 0.2404201413786482 0.0 response_to_muscle_activity GO:0014850 12133 7 45 1 29 1 1 false 0.24137931034482749 0.24137931034482749 6.407052883814491E-7 synapsis GO:0007129 12133 14 45 1 58 1 2 false 0.24137931034483048 0.24137931034483048 9.859073675355085E-14 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 45 9 5447 43 3 false 0.24187019323221623 0.24187019323221623 0.0 regulation_of_GTPase_activity GO:0043087 12133 277 45 1 1145 1 3 false 0.24192139737991364 0.24192139737991364 2.6919247726004267E-274 male_sex_differentiation GO:0046661 12133 105 45 1 3074 8 2 false 0.24297443939248878 0.24297443939248878 4.0305150218166505E-198 nucleus_organization GO:0006997 12133 62 45 1 2031 9 1 false 0.24390032584020607 0.24390032584020607 6.73570952581451E-120 cytokine_biosynthetic_process GO:0042089 12133 89 45 1 364 1 2 false 0.24450549450550926 0.24450549450550926 2.424583571152321E-87 insulin_receptor_signaling_pathway GO:0008286 12133 151 45 1 617 1 2 false 0.24473257698538148 0.24473257698538148 2.0667953594506098E-148 monosaccharide_biosynthetic_process GO:0046364 12133 62 45 1 253 1 2 false 0.24505928853752568 0.24505928853752568 1.1247044052233336E-60 positive_regulation_of_innate_immune_response GO:0045089 12133 178 45 2 740 4 4 false 0.24554603277379125 0.24554603277379125 1.4450011889246649E-176 RNA_polymerase_II_transcription_factor_binding_transcription_factor_activity_involved_in_negative_regulation_of_transcription GO:0001191 12133 24 45 1 521 6 2 false 0.24750467547247806 0.24750467547247806 6.640599439430319E-42 metal_ion_transmembrane_transporter_activity GO:0046873 12133 263 45 2 527 2 2 false 0.24857685009499134 0.24857685009499134 6.55805140577772E-158 commitment_complex GO:0000243 12133 1 45 1 4 1 2 false 0.25000000000000006 0.25000000000000006 0.25000000000000006 regulation_of_response_to_biotic_stimulus GO:0002831 12133 80 45 1 2255 8 2 false 0.2513084626939449 0.2513084626939449 1.6552927666708391E-149 channel_regulator_activity GO:0016247 12133 66 45 1 10257 45 2 false 0.2525746728264413 0.2525746728264413 1.2576121117294417E-172 regulation_of_cell_differentiation GO:0045595 12133 872 45 5 6612 26 3 false 0.2527640973541711 0.2527640973541711 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 45 1 2025 3 2 false 0.2535744732677491 0.2535744732677491 5.184659787643375E-271 positive_regulation_of_protein_modification_process GO:0031401 12133 708 45 4 2417 9 3 false 0.2540232358884416 0.2540232358884416 0.0 identical_protein_binding GO:0042802 12133 743 45 6 6397 37 1 false 0.254841084632997 0.254841084632997 0.0 regulation_of_transferase_activity GO:0051338 12133 667 45 2 2708 4 2 false 0.25542175436437853 0.25542175436437853 0.0 RNA_polymerase_II_transcription_cofactor_activity GO:0001104 12133 67 45 2 477 7 3 false 0.2564062890987355 0.2564062890987355 1.6403588657259362E-83 DNA_replication_initiation GO:0006270 12133 38 45 1 791 6 2 false 0.2564787951974037 0.2564787951974037 9.550826810910352E-66 negative_regulation_of_peptidyl-lysine_acetylation GO:2000757 12133 12 45 1 128 3 3 false 0.2575342144731943 0.2575342144731943 4.214777386482513E-17 positive_regulation_of_histone_modification GO:0031058 12133 40 45 1 963 7 4 false 0.2576382720368672 0.2576382720368672 8.380486405163906E-72 regulation_of_neuron_apoptotic_process GO:0043523 12133 143 45 1 1030 2 3 false 0.2585109494560741 0.2585109494560741 1.751953609038846E-179 single-organism_transport GO:0044765 12133 2323 45 10 8134 28 2 false 0.25870860553376007 0.25870860553376007 0.0 inositol_lipid-mediated_signaling GO:0048017 12133 173 45 1 1813 3 1 false 0.25994797504812645 0.25994797504812645 3.525454591975737E-247 muscle_tissue_development GO:0060537 12133 295 45 1 1132 1 1 false 0.26060070671386704 0.26060070671386704 3.412889797328503E-281 regulation_of_phosphorylation GO:0042325 12133 845 45 3 1820 4 2 false 0.26069661167854885 0.26069661167854885 0.0 cellular_chemical_homeostasis GO:0055082 12133 525 45 4 734 4 2 false 0.2608760978250313 0.2608760978250313 1.1478565010718528E-189 regulation_of_fatty_acid_metabolic_process GO:0019217 12133 55 45 1 392 2 3 false 0.26123492875407356 0.26123492875407356 1.5856324392591436E-68 regulation_of_homeostatic_process GO:0032844 12133 239 45 2 6742 28 2 false 0.2613890172569857 0.2613890172569857 0.0 peptidyl-lysine_acetylation GO:0018394 12133 127 45 3 198 3 2 false 0.26163557254926695 0.26163557254926695 1.293028032371008E-55 methyltransferase_complex GO:0034708 12133 62 45 1 9248 45 2 false 0.2617166092780113 0.2617166092780113 4.919625587422917E-161 regulation_of_neuron_death GO:1901214 12133 151 45 1 1070 2 2 false 0.2624410970162303 0.2624410970162303 2.12628458479716E-188 regulation_of_cell_division GO:0051302 12133 75 45 1 6427 26 2 false 0.26345899398191186 0.26345899398191186 9.599183496643589E-177 protein_tetramerization GO:0051262 12133 76 45 1 288 1 1 false 0.26388888888887596 0.26388888888887596 1.240191410365077E-71 actin_cytoskeleton_reorganization GO:0031532 12133 53 45 1 373 2 1 false 0.2643201014730844 0.2643201014730844 1.0372113100782682E-65 gene_silencing GO:0016458 12133 87 45 1 7626 27 2 false 0.2667936282504206 0.2667936282504206 5.995921436880012E-206 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 45 19 10446 45 1 false 0.2689714045772513 0.2689714045772513 0.0 negative_regulation_of_biological_process GO:0048519 12133 2732 45 14 10446 45 2 false 0.2724455427800331 0.2724455427800331 0.0 U2-type_spliceosomal_complex GO:0005684 12133 3 45 1 150 15 1 false 0.27263740250317997 0.27263740250317997 1.813894431344149E-6 positive_regulation_of_endocytosis GO:0045807 12133 63 45 1 1023 5 4 false 0.27272517922708284 0.27272517922708284 3.3235317732048763E-102 peptidyl-serine_phosphorylation GO:0018105 12133 121 45 1 1201 3 2 false 0.27302324515508136 0.27302324515508136 1.0029038835537004E-169 pore_complex GO:0046930 12133 84 45 1 5051 19 3 false 0.2732755458728679 0.2732755458728679 5.4712090537168384E-185 membrane_invagination GO:0010324 12133 411 45 2 784 2 1 false 0.27450347955270393 0.27450347955270393 8.658368437912315E-235 hexose_biosynthetic_process GO:0019319 12133 57 45 1 206 1 2 false 0.2766990291262256 0.2766990291262256 2.7565278967151444E-52 regulation_of_innate_immune_response GO:0045088 12133 226 45 2 868 4 3 false 0.2791147566981166 0.2791147566981166 2.196344369914344E-215 response_to_carbohydrate_stimulus GO:0009743 12133 116 45 1 1822 5 2 false 0.2805660638054063 0.2805660638054063 8.541992370523989E-187 response_to_oxidative_stress GO:0006979 12133 221 45 2 2540 12 1 false 0.2809296133244933 0.2809296133244933 0.0 regulation_of_lipid_metabolic_process GO:0019216 12133 182 45 2 4352 25 2 false 0.2812832280288968 0.2812832280288968 0.0 positive_regulation_of_purine_nucleotide_biosynthetic_process GO:1900373 12133 77 45 1 273 1 4 false 0.2820512820512513 0.2820512820512513 5.5014514459438226E-70 mRNA_stabilization GO:0048255 12133 22 45 3 33 3 2 false 0.28225806451612856 0.28225806451612856 5.166978132108427E-9 cellular_potassium_ion_transport GO:0071804 12133 92 45 1 7541 27 2 false 0.28251363517681627 0.28251363517681627 4.105440908779901E-215 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 45 11 6103 44 3 false 0.28292300931117376 0.28292300931117376 0.0 DNA_geometric_change GO:0032392 12133 55 45 1 194 1 1 false 0.2835051546391922 0.2835051546391922 9.185000733353143E-50 fatty_acid_oxidation GO:0019395 12133 61 45 1 215 1 2 false 0.2837209302325442 0.2837209302325442 3.380632905361965E-55 activation_of_immune_response GO:0002253 12133 341 45 2 1618 5 2 false 0.2847795440822618 0.2847795440822618 0.0 immune_system_development GO:0002520 12133 521 45 2 3460 7 2 false 0.28499293027971145 0.28499293027971145 0.0 reproductive_system_development GO:0061458 12133 216 45 1 2686 4 1 false 0.2850447402487203 0.2850447402487203 0.0 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 45 1 856 1 3 false 0.285046728972063 0.285046728972063 2.175375701359491E-221 U2-type_prespliceosome GO:0071004 12133 1 45 1 7 2 4 false 0.2857142857142857 0.2857142857142857 0.14285714285714285 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 45 1 1199 11 2 false 0.2859222507360302 0.2859222507360302 9.194442294553035E-70 negative_regulation_of_neuron_death GO:1901215 12133 97 45 1 626 2 3 false 0.286103514376935 0.286103514376935 1.335599710621913E-116 negative_regulation_of_neuron_apoptotic_process GO:0043524 12133 92 45 1 593 2 4 false 0.2864386308738622 0.2864386308738622 1.6237814014065637E-110 regulation_of_steroid_biosynthetic_process GO:0050810 12133 42 45 1 146 1 3 false 0.2876712328767199 0.2876712328767199 1.231507741439357E-37 negative_regulation_of_mRNA_splicing,_via_spliceosome GO:0048025 12133 11 45 2 207 20 4 false 0.2878005198750699 0.2878005198750699 1.749347829328537E-18 positive_regulation_of_nucleotide_biosynthetic_process GO:0030810 12133 77 45 1 1402 6 4 false 0.28790746185077565 0.28790746185077565 6.104501177954134E-129 RNA_polymerase_II_transcription_factor_binding_transcription_factor_activity GO:0001076 12133 88 45 2 1484 18 4 false 0.28968814313851887 0.28968814313851887 2.1138779413162717E-144 regulation_of_myeloid_leukocyte_differentiation GO:0002761 12133 70 45 1 240 1 3 false 0.29166666666666835 0.29166666666666835 2.1370679189634935E-62 gluconeogenesis GO:0006094 12133 54 45 1 185 1 2 false 0.2918918918919016 0.2918918918919016 4.74373526943691E-48 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 45 1 195 1 4 false 0.2923076923077087 0.2923076923077087 1.081664723883568E-50 exonuclease_activity GO:0004527 12133 58 45 1 197 1 1 false 0.2944162436548024 0.2944162436548024 2.2584639500539737E-51 nuclear_matrix GO:0016363 12133 81 45 2 2767 37 2 false 0.29534814046091273 0.29534814046091273 2.9785824972298125E-158 histone_H4-K5_acetylation GO:0043981 12133 13 45 1 44 1 1 false 0.29545454545454575 0.29545454545454575 1.9262060287683342E-11 histone_H4-K8_acetylation GO:0043982 12133 13 45 1 44 1 1 false 0.29545454545454575 0.29545454545454575 1.9262060287683342E-11 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 45 9 3780 32 4 false 0.2959099211380111 0.2959099211380111 0.0 DNA-dependent_DNA_replication GO:0006261 12133 93 45 2 257 3 1 false 0.29732132639047293 0.29732132639047293 1.72483826119428E-72 myeloid_cell_homeostasis GO:0002262 12133 111 45 1 1628 5 2 false 0.29780079548482163 0.29780079548482163 2.626378318706563E-175 hydrolase_activity GO:0016787 12133 2556 45 6 4901 9 1 false 0.29787301704008745 0.29787301704008745 0.0 RNA_3'-end_processing GO:0031123 12133 98 45 6 601 28 1 false 0.2981905071256968 0.2981905071256968 1.9130441150898719E-115 mRNA_3'-splice_site_recognition GO:0000389 12133 5 45 2 18 4 1 false 0.29901960784313913 0.29901960784313913 1.1671335200746984E-4 ATP_binding GO:0005524 12133 1212 45 4 1638 4 3 false 0.29936071055097485 0.29936071055097485 0.0 positive_regulation_of_histone_acetylation GO:0035066 12133 16 45 1 144 3 4 false 0.2995173840244142 0.2995173840244142 1.4536629180584386E-21 positive_regulation_of_mitochondrion_organization GO:0010822 12133 43 45 1 385 3 3 false 0.2997249160761194 0.2997249160761194 4.6200993055738E-58 ATPase_activity,_coupled GO:0042623 12133 228 45 4 307 4 1 false 0.3021471043694826 0.3021471043694826 1.7947531856464704E-75 endodeoxyribonuclease_activity GO:0004520 12133 26 45 1 86 1 2 false 0.302325581395351 0.302325581395351 1.385136351497846E-22 negative_regulation_of_binding GO:0051100 12133 72 45 1 9054 45 3 false 0.3024372075848774 0.3024372075848774 1.0408990583833388E-181 positive_regulation_of_nucleotide_metabolic_process GO:0045981 12133 83 45 1 2578 11 4 false 0.30280393833045316 0.30280393833045316 1.0942419479084622E-158 meiosis_I GO:0007127 12133 55 45 1 1243 8 3 false 0.3044830673092818 0.3044830673092818 2.718753320211584E-97 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 45 9 5032 43 4 false 0.30526963269480917 0.30526963269480917 0.0 regulation_of_cellular_component_organization GO:0051128 12133 1152 45 7 7336 35 2 false 0.30562680158555383 0.30562680158555383 0.0 regulation_of_skeletal_muscle_tissue_development GO:0048641 12133 63 45 1 206 1 2 false 0.3058252427184593 0.3058252427184593 1.364605297408496E-54 transferase_activity,_transferring_acyl_groups GO:0016746 12133 156 45 1 1779 4 1 false 0.3074848080273228 0.3074848080273228 7.715087379917376E-229 90S_preribosome GO:0030686 12133 8 45 2 14 2 1 false 0.3076923076923073 0.3076923076923073 3.330003330003327E-4 response_to_abiotic_stimulus GO:0009628 12133 676 45 3 5200 15 1 false 0.30829275607750356 0.30829275607750356 0.0 immune_response GO:0006955 12133 1006 45 4 5335 15 2 false 0.309204597749566 0.309204597749566 0.0 RNA_polymerase_II_transcription_factor_binding GO:0001085 12133 133 45 2 715 6 1 false 0.3101820606549322 0.3101820606549322 1.758868350294454E-148 monovalent_inorganic_cation_homeostasis GO:0055067 12133 56 45 1 330 2 1 false 0.31102514506767237 0.31102514506767237 9.24814230107908E-65 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 45 29 4989 42 5 false 0.31132413819031723 0.31132413819031723 0.0 regulation_of_carbohydrate_biosynthetic_process GO:0043255 12133 52 45 1 3097 22 3 false 0.31188942244856843 0.31188942244856843 3.6702105296750396E-114 adenyl_ribonucleotide_binding GO:0032559 12133 1231 45 4 1645 4 2 false 0.31320954047549715 0.31320954047549715 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 45 4 1650 4 1 false 0.31347325632894396 0.31347325632894396 0.0 pre-mRNA_binding GO:0036002 12133 10 45 1 763 28 1 false 0.3134946618372232 0.3134946618372232 5.757557985229243E-23 cell_cycle GO:0007049 12133 1295 45 6 7541 27 1 false 0.31362680418210176 0.31362680418210176 0.0 regulation_of_DNA_metabolic_process GO:0051052 12133 188 45 2 4316 26 3 false 0.31399758428440117 0.31399758428440117 0.0 poly(A)_RNA_binding GO:0008143 12133 11 45 1 94 3 2 false 0.31454596998000534 0.31454596998000534 1.4483869139240058E-14 regulation_of_DNA_binding GO:0051101 12133 67 45 1 2162 12 2 false 0.31527762318704966 0.31527762318704966 3.7616659824415835E-129 maturation_of_5.8S_rRNA GO:0000460 12133 12 45 1 102 3 1 false 0.31578334304018757 0.31578334304018757 7.4019739755232135E-16 cellular_cation_homeostasis GO:0030003 12133 289 45 2 513 2 2 false 0.31688596491226906 0.31688596491226906 6.525965777081911E-152 intracellular_protein_transport GO:0006886 12133 658 45 6 1672 12 3 false 0.3173004526338583 0.3173004526338583 0.0 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 45 9 3453 31 4 false 0.31746305426417254 0.31746305426417254 0.0 sodium_ion_transport GO:0006814 12133 95 45 1 545 2 2 false 0.3185037776579273 0.3185037776579273 6.918862196703055E-109 sodium_ion_transmembrane_transport GO:0035725 12133 68 45 1 565 3 2 false 0.31984590445849154 0.31984590445849154 1.2033655972436562E-89 cell-cell_junction_assembly GO:0007043 12133 58 45 1 181 1 2 false 0.3204419889502846 0.3204419889502846 7.851737058026464E-49 histone_deacetylase_complex GO:0000118 12133 50 45 1 3138 24 2 false 0.3208544855759179 0.3208544855759179 6.6201010514053174E-111 viral_infectious_cycle GO:0019058 12133 213 45 5 557 10 1 false 0.3222641120333822 0.3222641120333822 3.455075709157513E-160 regulation_of_primary_metabolic_process GO:0080090 12133 3921 45 25 7507 44 2 false 0.32380436409852387 0.32380436409852387 0.0 establishment_of_localization GO:0051234 12133 2833 45 14 10446 45 2 false 0.3243715860832883 0.3243715860832883 0.0 positive_regulation_of_immune_effector_process GO:0002699 12133 87 45 1 706 3 3 false 0.3264066190047665 0.3264066190047665 7.573271162497966E-114 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 45 1 254 1 3 false 0.3267716535432695 0.3267716535432695 3.7262148804586973E-69 regulation_of_defense_response_to_virus_by_host GO:0050691 12133 20 45 1 61 1 1 false 0.32786885245902 0.32786885245902 1.6034257630742549E-16 neurotrophin_signaling_pathway GO:0038179 12133 253 45 1 2018 3 2 false 0.33107409492035167 0.33107409492035167 0.0 microtubule_cytoskeleton GO:0015630 12133 734 45 3 1430 4 1 false 0.3324420855496282 0.3324420855496282 0.0 anatomical_structure_homeostasis GO:0060249 12133 166 45 2 990 7 1 false 0.3330532836994742 0.3330532836994742 1.128853988781411E-193 regulation_of_muscle_tissue_development GO:1901861 12133 105 45 1 1351 5 2 false 0.33312882852355696 0.33312882852355696 1.3105194568745759E-159 importin-alpha_export_receptor_activity GO:0008262 12133 1 45 1 3 1 1 false 0.33333333333333337 0.33333333333333337 0.33333333333333337 histone_acetyltransferase_activity_(H4-K16_specific) GO:0046972 12133 7 45 1 21 1 2 false 0.33333333333333354 0.33333333333333354 8.599931200550419E-6 nucleotide_binding GO:0000166 12133 1997 45 21 2103 21 2 false 0.3357354753026629 0.3357354753026629 1.0169073992212018E-181 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 45 5 5778 20 3 false 0.33674032002463933 0.33674032002463933 0.0 positive_regulation_of_biological_process GO:0048518 12133 3081 45 15 10446 45 2 false 0.3371594142189658 0.3371594142189658 0.0 fat_cell_differentiation GO:0045444 12133 123 45 1 2154 7 1 false 0.33779475283904337 0.33779475283904337 4.3402768719462724E-204 regulation_of_steroid_metabolic_process GO:0019218 12133 56 45 1 301 2 2 false 0.3379844961239699 0.3379844961239699 2.659882776337694E-62 cellular_protein_catabolic_process GO:0044257 12133 409 45 3 3174 16 3 false 0.3407599137175472 0.3407599137175472 0.0 chromatin_DNA_binding GO:0031490 12133 25 45 1 434 7 2 false 0.34183135502553524 0.34183135502553524 3.625934707175437E-41 multicellular_organismal_homeostasis GO:0048871 12133 128 45 1 4332 14 2 false 0.34330868153140603 0.34330868153140603 8.184767611609268E-250 energy_derivation_by_oxidation_of_organic_compounds GO:0015980 12133 271 45 1 788 1 2 false 0.34390862944148476 0.34390862944148476 1.8657076333624725E-219 positive_regulation_of_purine_nucleotide_metabolic_process GO:1900544 12133 82 45 1 1209 6 3 false 0.3444702493631746 0.3444702493631746 1.376514335843937E-129 neuronal_cell_body GO:0043025 12133 215 45 1 621 1 2 false 0.34621578099842243 0.34621578099842243 3.1563152846547707E-173 purine_nucleoside_metabolic_process GO:0042278 12133 1054 45 6 1257 6 2 false 0.34676131873282445 0.34676131873282445 1.399683863089717E-240 carboxylic_acid_binding GO:0031406 12133 186 45 1 2280 5 1 false 0.34680970332911004 0.34680970332911004 4.771798836819993E-279 positive_regulation_of_peptidyl-lysine_acetylation GO:2000758 12133 17 45 1 127 3 3 false 0.35262092238470233 0.35262092238470233 1.8751500945612253E-21 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 45 1 2735 15 4 false 0.352824405610372 0.352824405610372 2.836340851870023E-153 steroid_hormone_receptor_binding GO:0035258 12133 62 45 2 104 2 1 false 0.3530619865571091 0.3530619865571091 4.2931773052216616E-30 cytokine_metabolic_process GO:0042107 12133 92 45 1 3431 16 1 false 0.3532872641322658 0.3532872641322658 2.347983592216771E-183 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 45 1 1663 5 2 false 0.35401125767979397 0.35401125767979397 7.181952736648417E-207 regulation_of_cation_channel_activity GO:2001257 12133 33 45 1 244 3 2 false 0.35458869202029614 0.35458869202029614 1.3783310605710322E-41 positive_regulation_of_response_to_external_stimulus GO:0032103 12133 126 45 1 1783 6 3 false 0.3562035591881383 0.3562035591881383 4.953245093659787E-197 muscle_system_process GO:0003012 12133 252 45 1 1272 2 1 false 0.35710256372210103 0.35710256372210103 3.711105192357829E-274 regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033146 12133 20 45 1 56 1 2 false 0.35714285714286187 0.35714285714286187 1.2728904491493287E-15 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 45 6 10311 45 3 false 0.3572752940311332 0.3572752940311332 0.0 cell_chemotaxis GO:0060326 12133 132 45 1 2155 7 3 false 0.35795785061857566 0.35795785061857566 6.49351277121459E-215 RNA_polymerase_II_repressing_transcription_factor_binding GO:0001103 12133 31 45 1 296 4 2 false 0.3591178689889594 0.3591178689889594 1.0279031855917918E-42 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 45 1 630 1 2 false 0.3603174603174997 0.3603174603174997 4.4826406352842784E-178 establishment_of_localization_in_cell GO:0051649 12133 1633 45 10 2978 16 2 false 0.36060615293246034 0.36060615293246034 0.0 organelle_assembly GO:0070925 12133 210 45 2 2677 16 2 false 0.36103992519876266 0.36103992519876266 7.5039E-319 SAGA-type_complex GO:0070461 12133 26 45 1 72 1 1 false 0.36111111111111127 0.36111111111111127 3.624038800506386E-20 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 45 2 1975 3 1 false 0.3614353520127967 0.3614353520127967 0.0 regulation_of_defense_response GO:0031347 12133 387 45 2 1253 4 2 false 0.36390463686130814 0.36390463686130814 0.0 telomere_maintenance_via_telomere_lengthening GO:0010833 12133 37 45 2 61 2 1 false 0.3639344262295161 0.3639344262295161 1.6824333127705717E-17 protein_stabilization GO:0050821 12133 60 45 2 99 2 1 false 0.36487322201606387 0.36487322201606387 1.818679918792965E-28 ncRNA_metabolic_process GO:0034660 12133 258 45 4 3294 39 1 false 0.36536096271718566 0.36536096271718566 0.0 positive_regulation_of_cell_cycle GO:0045787 12133 98 45 1 3492 16 3 false 0.3664667393874437 0.3664667393874437 2.23767062140918E-193 DNA_biosynthetic_process GO:0071897 12133 268 45 3 3979 32 3 false 0.36676096183175266 0.36676096183175266 0.0 regulation_of_striated_muscle_tissue_development GO:0016202 12133 105 45 1 286 1 3 false 0.36713286713287985 0.36713286713287985 4.516187028693684E-81 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 45 1 1198 7 4 false 0.36870162603449513 0.36870162603449513 2.335035261625238E-122 development_of_primary_sexual_characteristics GO:0045137 12133 174 45 1 3105 8 3 false 0.369912549401378 0.369912549401378 2.1612319791507408E-290 regulation_of_glucose_metabolic_process GO:0010906 12133 74 45 1 200 1 2 false 0.3699999999999865 0.3699999999999865 9.949659617427537E-57 transcriptional_repressor_complex GO:0017053 12133 60 45 1 3138 24 2 false 0.37190135765371096 0.37190135765371096 2.3309177667820233E-128 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 45 26 6638 44 2 false 0.3724501111989107 0.3724501111989107 0.0 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 45 2 147 2 1 false 0.37321778026277286 0.37321778026277286 3.485982605742994E-42 immune_response-regulating_cell_surface_receptor_signaling_pathway_involved_in_phagocytosis GO:0002433 12133 72 45 1 500 3 2 false 0.37341304295339856 0.37341304295339856 6.2427882790248544E-89 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 45 1 859 2 3 false 0.3735329474564912 0.3735329474564912 3.480270935062193E-190 nuclear_periphery GO:0034399 12133 97 45 2 2767 37 2 false 0.37464034750209474 0.37464034750209474 7.041791399430774E-182 protein_autophosphorylation GO:0046777 12133 173 45 1 1195 3 1 false 0.37473497880419065 0.37473497880419065 7.421869914925723E-214 neuron_death GO:0070997 12133 170 45 1 1525 4 1 false 0.37703581203251874 0.37703581203251874 9.045134214386945E-231 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 45 2 7778 32 4 false 0.3770788075251189 0.3770788075251189 0.0 potassium_ion_transport GO:0006813 12133 115 45 1 545 2 2 false 0.37779951430121167 0.37779951430121167 2.5935886393871475E-121 protein_transporter_activity GO:0008565 12133 81 45 1 1579 9 2 false 0.37822999221456594 0.37822999221456594 3.989743647530564E-138 cellular_response_to_interferon-gamma GO:0071346 12133 83 45 1 392 2 2 false 0.37906466934595223 0.37906466934595223 2.629901965674187E-87 sodium_ion_transmembrane_transporter_activity GO:0015081 12133 67 45 1 316 2 3 false 0.37962628089210476 0.37962628089210476 2.2934303131006308E-70 negative_regulation_of_cellular_process GO:0048523 12133 2515 45 13 9689 45 3 false 0.38062055541339634 0.38062055541339634 0.0 SH3/SH2_adaptor_activity GO:0005070 12133 48 45 1 126 1 2 false 0.38095238095239137 0.38095238095239137 5.926155314091347E-36 coagulation GO:0050817 12133 446 45 2 4095 12 1 false 0.38187081312816606 0.38187081312816606 0.0 gonad_development GO:0008406 12133 150 45 1 2876 9 4 false 0.38293205186802104 0.38293205186802104 4.529833702866928E-255 regulation_of_inflammatory_response GO:0050727 12133 151 45 1 702 2 3 false 0.3841723870255134 0.3841723870255134 5.1007818439049374E-158 cation_homeostasis GO:0055080 12133 330 45 2 532 2 1 false 0.3843294677373803 0.3843294677373803 1.1320770482912473E-152 response_to_cytokine_stimulus GO:0034097 12133 461 45 2 1783 5 1 false 0.38524450295567825 0.38524450295567825 0.0 DNA_replication GO:0006260 12133 257 45 3 3702 32 3 false 0.3852940828106542 0.3852940828106542 0.0 nucleoside_triphosphate_biosynthetic_process GO:0009142 12133 94 45 1 1209 6 2 false 0.38533893989139484 0.38533893989139484 7.9535920251409005E-143 endonuclease_activity GO:0004519 12133 76 45 1 197 1 1 false 0.3857868020304401 0.3857868020304401 1.5249800288122344E-56 telomere_maintenance_via_semi-conservative_replication GO:0032201 12133 23 45 1 106 2 2 false 0.3884995507637007 0.3884995507637007 8.898323406667189E-24 chromosome_segregation GO:0007059 12133 136 45 1 7541 27 1 false 0.3887439687389389 0.3887439687389389 5.819868354628029E-295 recombinational_repair GO:0000725 12133 48 45 1 416 4 2 false 0.3887821728336801 0.3887821728336801 4.005015877906007E-64 response_to_starvation GO:0042594 12133 104 45 1 2586 12 2 false 0.3896018241661966 0.3896018241661966 1.0260437683061592E-188 protein_catabolic_process GO:0030163 12133 498 45 3 3569 16 2 false 0.39045629336412513 0.39045629336412513 0.0 protein_N-terminus_binding GO:0047485 12133 85 45 1 6397 37 1 false 0.3912451480157369 0.3912451480157369 1.5319897739448716E-195 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 45 2 1079 3 3 false 0.3915421137192442 0.3915421137192442 5.98264E-319 regulation_of_leukocyte_differentiation GO:1902105 12133 144 45 1 1523 5 3 false 0.39183219700247846 0.39183219700247846 2.939857689533629E-206 regulation_of_cytoskeleton_organization GO:0051493 12133 250 45 2 955 5 2 false 0.39207588611192734 0.39207588611192734 1.2229840665192896E-237 positive_regulation_of_lipid_metabolic_process GO:0045834 12133 83 45 1 2379 14 3 false 0.39259085421608286 0.39259085421608286 9.636146254923238E-156 positive_regulation_of_cytoskeleton_organization GO:0051495 12133 96 45 1 818 4 3 false 0.39366767598464736 0.39366767598464736 7.819752088827555E-128 regulation_of_DNA_recombination GO:0000018 12133 38 45 1 324 4 2 false 0.3943702061316567 0.3943702061316567 1.9894741609704344E-50 striated_muscle_contraction GO:0006941 12133 87 45 1 220 1 1 false 0.39545454545453296 0.39545454545453296 1.3725907999420383E-63 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 45 1 750 1 3 false 0.39866666666682765 0.39866666666682765 3.090255244762607E-218 regulation_of_cytokine_biosynthetic_process GO:0042035 12133 80 45 1 3656 23 5 false 0.39975951464750864 0.39975951464750864 1.557250442043908E-166 regulation_of_mitochondrion_organization GO:0010821 12133 64 45 1 661 5 2 false 0.39999257858682696 0.39999257858682696 9.542606350434685E-91 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 45 4 2780 7 2 false 0.40232898291120606 0.40232898291120606 0.0 skeletal_muscle_cell_differentiation GO:0035914 12133 57 45 1 251 2 2 false 0.40331474103583304 0.40331474103583304 6.638453930425573E-58 cell_cycle_phase_transition GO:0044770 12133 415 45 2 953 3 1 false 0.4036377908452264 0.4036377908452264 1.4433288987581492E-282 regulation_of_protein_metabolic_process GO:0051246 12133 1388 45 9 5563 32 3 false 0.4038181763399422 0.4038181763399422 0.0 Fc_receptor_signaling_pathway GO:0038093 12133 76 45 1 188 1 1 false 0.40425531914892643 0.40425531914892643 1.381050418692459E-54 catabolic_process GO:0009056 12133 2164 45 13 8027 44 1 false 0.4044646406917414 0.4044646406917414 0.0 transcription_corepressor_activity GO:0003714 12133 180 45 3 479 6 2 false 0.40530280434460897 0.40530280434460897 5.2319775680795235E-137 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 45 1 1130 3 2 false 0.4060954260582573 0.4060954260582573 1.9819409219356823E-214 transporter_activity GO:0005215 12133 746 45 4 10383 45 2 false 0.40680754932078356 0.40680754932078356 0.0 peptidyl-tyrosine_phosphorylation GO:0018108 12133 191 45 1 1195 3 2 false 0.4072252560363684 0.4072252560363684 2.9198379950600046E-227 regulation_of_Rho_GTPase_activity GO:0032319 12133 95 45 1 233 1 2 false 0.40772532188845706 0.40772532188845706 7.3761210037366725E-68 nuclease_activity GO:0004518 12133 197 45 1 853 2 2 false 0.4087699310360668 0.4087699310360668 1.9441890942275812E-199 glutamate_binding GO:0016595 12133 45 45 1 110 1 1 false 0.40909090909090273 0.40909090909090273 6.211900206572506E-32 histone_H4-K16_acetylation GO:0043984 12133 18 45 1 44 1 1 false 0.4090909090909085 0.4090909090909085 9.7131635117721E-13 cellular_catabolic_process GO:0044248 12133 1972 45 13 7289 44 2 false 0.41006915270582556 0.41006915270582556 0.0 RNA_polymerase_II_activating_transcription_factor_binding GO:0001102 12133 44 45 1 357 4 2 false 0.4105171354714594 0.4105171354714594 2.031577352129153E-57 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 45 1 912 1 2 false 0.4111842105262834 0.4111842105262834 2.059888800891414E-267 Cul4-RING_ubiquitin_ligase_complex GO:0080008 12133 21 45 1 90 2 1 false 0.41423220973782965 0.41423220973782965 5.884575201651408E-21 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 45 2 1398 5 2 false 0.41470074881286517 0.41470074881286517 0.0 platelet_activation GO:0030168 12133 203 45 1 863 2 2 false 0.4153293561283654 0.4153293561283654 1.0918730712206789E-203 MLL1/2_complex GO:0044665 12133 25 45 1 60 1 1 false 0.41666666666667024 0.41666666666667024 1.9262093107921078E-17 intracellular_protein_kinase_cascade GO:0007243 12133 806 45 2 1813 3 1 false 0.41714583710526376 0.41714583710526376 0.0 regulation_of_immune_system_process GO:0002682 12133 794 45 4 6789 28 2 false 0.4177815185935835 0.4177815185935835 0.0 potassium_ion_transmembrane_transport GO:0071805 12133 92 45 1 556 3 2 false 0.41941821311218713 0.41941821311218713 1.0312185181817459E-107 regulation_of_myeloid_cell_differentiation GO:0045637 12133 124 45 1 1656 7 4 false 0.42064861793291736 0.42064861793291736 1.1641273300011644E-190 regulation_of_cellular_carbohydrate_metabolic_process GO:0010675 12133 91 45 1 4058 24 3 false 0.4206732941600473 0.4206732941600473 1.6448652824301034E-188 purine_nucleoside_triphosphate_biosynthetic_process GO:0009145 12133 88 45 1 1010 6 2 false 0.4221177943912318 0.4221177943912318 3.834842802403038E-129 localization GO:0051179 12133 3467 45 16 10446 45 1 false 0.4223049348192458 0.4223049348192458 0.0 ligand-dependent_nuclear_receptor_transcription_coactivator_activity GO:0030374 12133 44 45 1 264 3 1 false 0.42261922038712346 0.42261922038712346 3.338461966138287E-51 transferase_activity GO:0016740 12133 1779 45 4 4901 9 1 false 0.4237964414704048 0.4237964414704048 0.0 purine_ribonucleoside_triphosphate_biosynthetic_process GO:0009206 12133 88 45 1 1004 6 3 false 0.424102990641689 0.424102990641689 6.6360285282771E-129 response_to_biotic_stimulus GO:0009607 12133 494 45 2 5200 15 1 false 0.42415515600330356 0.42415515600330356 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 45 5 1180 12 1 false 0.4263990830523085 0.4263990830523085 0.0 Fc_receptor_mediated_stimulatory_signaling_pathway GO:0002431 12133 76 45 1 178 1 1 false 0.42696629213485654 0.42696629213485654 2.9073989409378337E-52 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 45 1 6380 26 3 false 0.42716924228418424 0.42716924228418424 2.5067679665083333E-283 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 45 1 587 1 2 false 0.42759795570703146 0.42759795570703146 2.854325455984618E-173 homeostatic_process GO:0042592 12133 990 45 7 2082 13 1 false 0.4283021353684524 0.4283021353684524 0.0 histone_acetyltransferase_complex GO:0000123 12133 72 45 1 3138 24 2 false 0.42831144713162483 0.42831144713162483 2.423530971941831E-148 organic_substance_catabolic_process GO:1901575 12133 2054 45 13 7502 44 2 false 0.4292686862667794 0.4292686862667794 0.0 leukocyte_chemotaxis GO:0030595 12133 107 45 1 249 1 2 false 0.4297188755020236 0.4297188755020236 2.556499812614757E-73 signal_transduction_by_phosphorylation GO:0023014 12133 307 45 1 3947 7 2 false 0.432919524656724 0.432919524656724 0.0 positive_regulation_of_DNA_metabolic_process GO:0051054 12133 92 45 1 2322 14 4 false 0.4331187402288247 0.4331187402288247 1.6937907011714837E-167 phosphatidylinositol_3-kinase_cascade GO:0014065 12133 75 45 1 173 1 1 false 0.4335260115606976 0.4335260115606976 6.333263082873936E-51 ribonucleoside_triphosphate_biosynthetic_process GO:0009201 12133 91 45 1 1007 6 2 false 0.43434598261888113 0.43434598261888113 4.751039484875125E-132 regulation_of_carbohydrate_metabolic_process GO:0006109 12133 96 45 1 4268 25 2 false 0.43468298658573395 0.43468298658573395 9.169265262763212E-199 positive_regulation_of_cell_communication GO:0010647 12133 820 45 3 4819 14 3 false 0.43484172620914213 0.43484172620914213 0.0 response_to_interferon-gamma GO:0034341 12133 97 45 1 900 5 2 false 0.4353488650541955 0.4353488650541955 5.665951698458868E-133 regulation_of_endocytosis GO:0030100 12133 113 45 1 1437 7 3 false 0.43704311299997234 0.43704311299997234 3.3139638850760945E-171 histone_acetyltransferase_activity_(H4-K5_specific) GO:0043995 12133 7 45 1 16 1 2 false 0.4374999999999999 0.4374999999999999 8.741258741258732E-5 histone_acetyltransferase_activity_(H4-K8_specific) GO:0043996 12133 7 45 1 16 1 2 false 0.4374999999999999 0.4374999999999999 8.741258741258732E-5 reciprocal_DNA_recombination GO:0035825 12133 33 45 1 190 3 1 false 0.4376810821379547 0.4376810821379547 1.0521505820531533E-37 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 45 11 2595 22 2 false 0.4379994280129275 0.4379994280129275 0.0 positive_regulation_of_immune_system_process GO:0002684 12133 540 45 3 3595 16 3 false 0.4397350066884987 0.4397350066884987 0.0 regulation_of_protein_modification_process GO:0031399 12133 1001 45 5 2566 11 2 false 0.43988017323943973 0.43988017323943973 0.0 regulation_of_lipid_biosynthetic_process GO:0046890 12133 85 45 1 3279 22 3 false 0.43993419979657816 0.43993419979657816 1.2266874982723732E-170 double-strand_break_repair_via_homologous_recombination GO:0000724 12133 48 45 1 109 1 2 false 0.4403669724770689 0.4403669724770689 4.364037891784993E-32 organelle_organization GO:0006996 12133 2031 45 9 7663 31 2 false 0.44152679648624615 0.44152679648624615 0.0 regulation_of_purine_nucleotide_biosynthetic_process GO:1900371 12133 146 45 1 574 2 3 false 0.4443451240795597 0.4443451240795597 1.1371703790830463E-140 protein_deacetylase_activity GO:0033558 12133 28 45 1 63 1 2 false 0.44444444444444187 0.44444444444444187 1.5890462849475085E-18 purine_nucleoside_biosynthetic_process GO:0042451 12133 113 45 1 1209 6 3 false 0.4456957616262503 0.4456957616262503 2.4070126005742053E-162 regulation_of_skeletal_muscle_cell_differentiation GO:2001014 12133 27 45 1 105 2 3 false 0.4499999999999779 0.4499999999999779 1.1402717682449654E-25 protein_localization_to_chromosome GO:0034502 12133 42 45 1 516 7 1 false 0.4500534398693141 0.4500534398693141 9.147552356323976E-63 response_to_organic_nitrogen GO:0010243 12133 519 45 2 1787 5 3 false 0.4520960171104089 0.4520960171104089 0.0 protein_phosphorylated_amino_acid_binding GO:0045309 12133 19 45 1 42 1 1 false 0.45238095238095566 0.45238095238095566 2.238261550776809E-12 leukocyte_migration GO:0050900 12133 224 45 1 1975 5 2 false 0.45258906432742335 0.45258906432742335 1.7898344026900835E-302 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 45 3 3605 21 4 false 0.4530168887699799 0.4530168887699799 0.0 cardiac_muscle_contraction GO:0060048 12133 68 45 1 150 1 2 false 0.45333333333334686 0.45333333333334686 2.0634364015669812E-44 regulation_of_peptidyl-tyrosine_phosphorylation GO:0050730 12133 150 45 1 812 3 2 false 0.45857103937838595 0.45857103937838595 5.072476466269739E-168 mitotic_recombination GO:0006312 12133 35 45 1 190 3 1 false 0.4590332213512377 0.4590332213512377 5.112114946281329E-39 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 45 3 2370 9 1 false 0.4613117337406659 0.4613117337406659 0.0 cellular_response_to_monosaccharide_stimulus GO:0071326 12133 48 45 1 104 1 2 false 0.4615384615384517 0.4615384615384517 8.570018550150511E-31 actin_filament-based_process GO:0030029 12133 431 45 2 7541 27 1 false 0.4620771841645117 0.4620771841645117 0.0 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 45 5 4044 21 3 false 0.4640751301600107 0.4640751301600107 0.0 endonucleolytic_cleavage_to_generate_mature_3'-end_of_SSU-rRNA_from_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000461 12133 2 45 1 8 2 3 false 0.46428571428571414 0.46428571428571414 0.035714285714285705 positive_regulation_of_peptidyl-tyrosine_phosphorylation GO:0050731 12133 113 45 1 602 3 3 false 0.4646529317139472 0.4646529317139472 1.3602790060815964E-125 cellular_respiration GO:0045333 12133 126 45 1 271 1 1 false 0.46494464944648656 0.46494464944648656 1.0574236582097445E-80 cytokine_binding GO:0019955 12133 107 45 1 6397 37 1 false 0.46521799656355567 0.46521799656355567 1.7233195864585648E-235 lipid_modification GO:0030258 12133 163 45 1 606 2 1 false 0.4659302293867891 0.4659302293867891 1.5937246255533045E-152 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 45 2 2896 9 3 false 0.4671491187604114 0.4671491187604114 0.0 monocarboxylic_acid_metabolic_process GO:0032787 12133 287 45 1 614 1 1 false 0.4674267100978451 0.4674267100978451 1.6797243192352778E-183 phagocytosis GO:0006909 12133 149 45 1 2417 10 2 false 0.47139489918050037 0.47139489918050037 3.130675140672653E-242 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 45 2 5157 18 3 false 0.47192472553298714 0.47192472553298714 0.0 regulation_of_translation GO:0006417 12133 210 45 2 3605 27 4 false 0.47250022615124154 0.47250022615124154 0.0 regulation_of_cellular_component_size GO:0032535 12133 157 45 1 7666 31 3 false 0.4741526361169677 0.4741526361169677 0.0 apoptotic_signaling_pathway GO:0097190 12133 305 45 1 3954 8 2 false 0.4741762602358457 0.4741762602358457 0.0 substrate-specific_transporter_activity GO:0022892 12133 620 45 4 746 4 1 false 0.4763203408868518 0.4763203408868518 1.886990037563331E-146 Fc-gamma_receptor_signaling_pathway_involved_in_phagocytosis GO:0038096 12133 72 45 1 151 1 4 false 0.47682119205296153 0.47682119205296153 6.349846956956757E-45 transmembrane_transporter_activity GO:0022857 12133 544 45 3 904 4 2 false 0.47807384233427536 0.47807384233427536 4.222056161945909E-263 regulation_of_systemic_arterial_blood_pressure GO:0003073 12133 56 45 1 117 1 1 false 0.4786324786324643 0.4786324786324643 9.090542259133476E-35 binding,_bridging GO:0060090 12133 129 45 1 8962 45 1 false 0.4800697308135832 0.4800697308135832 1.7318913122999068E-292 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 45 3 3910 21 3 false 0.48297292266885505 0.48297292266885505 0.0 response_to_growth_factor_stimulus GO:0070848 12133 545 45 2 1783 5 1 false 0.48353325630671695 0.48353325630671695 0.0 regulation_of_kinase_activity GO:0043549 12133 654 45 2 1335 3 3 false 0.48482215141370644 0.48482215141370644 0.0 transmembrane_transport GO:0055085 12133 728 45 3 7606 27 2 false 0.48523877777417174 0.48523877777417174 0.0 N-methyl-D-aspartate_selective_glutamate_receptor_activity GO:0004972 12133 17 45 1 35 1 1 false 0.4857142857142865 0.4857142857142865 2.2038238923005066E-10 RNA_polymerase_complex GO:0030880 12133 136 45 1 9248 45 2 false 0.4874114521831541 0.4874114521831541 4.112311514468251E-307 Rho_protein_signal_transduction GO:0007266 12133 178 45 1 365 1 1 false 0.4876712328767119 0.4876712328767119 3.561371803691081E-109 negative_regulation_of_immune_system_process GO:0002683 12133 144 45 1 3524 16 3 false 0.48777488955555337 0.48777488955555337 1.8096661454151343E-260 ribonucleotide_catabolic_process GO:0009261 12133 946 45 5 1294 6 3 false 0.48931961266204416 0.48931961266204416 0.0 purine_ribonucleoside_biosynthetic_process GO:0046129 12133 113 45 1 1064 6 3 false 0.4910171268962752 0.4910171268962752 9.6209174897115E-156 extracellular_ligand-gated_ion_channel_activity GO:0005230 12133 58 45 1 118 1 1 false 0.49152542372880365 0.49152542372880365 4.1752337744784736E-35 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 45 1 417 1 4 false 0.4916067146282839 0.4916067146282839 8.022991700655629E-125 protein_binding,_bridging GO:0030674 12133 116 45 1 6397 37 2 false 0.49289007343590857 0.49289007343590857 3.1111419589573665E-251 cell_cycle_arrest GO:0007050 12133 202 45 1 998 3 2 false 0.49299100914787947 0.49299100914787947 1.5077994882682823E-217 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 45 1 803 2 1 false 0.494616509784253 0.494616509784253 7.141936114023743E-209 cellular_response_to_hexose_stimulus GO:0071331 12133 47 45 1 95 1 2 false 0.4947368421052526 0.4947368421052526 3.1079707417037665E-28 calcium_ion_transmembrane_transport GO:0070588 12133 131 45 1 640 3 2 false 0.4975556775869845 0.4975556775869845 3.4276218198079466E-140 cation_channel_activity GO:0005261 12133 216 45 2 433 3 2 false 0.49826387958618773 0.49826387958618773 1.1777872542675005E-129 regulation_of_Rho_protein_signal_transduction GO:0035023 12133 149 45 1 299 1 2 false 0.4983277591973189 0.4983277591973189 2.1331125641940734E-89 nucleotide_catabolic_process GO:0009166 12133 969 45 5 1318 6 2 false 0.4989127590945578 0.4989127590945578 0.0 potassium_ion_transmembrane_transporter_activity GO:0015079 12133 92 45 1 315 2 3 false 0.4994843797391358 0.4994843797391358 4.7759735730125735E-82 divalent_inorganic_cation_transmembrane_transporter_activity GO:0072509 12133 126 45 1 431 2 2 false 0.49970323207273065 0.49970323207273065 1.8747555941678357E-112 maturation_of_5.8S_rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000466 12133 6 45 1 12 1 1 false 0.4999999999999995 0.4999999999999995 0.0010822510822510805 progressive_alteration_of_chromatin_involved_in_replicative_cell_aging GO:0001304 12133 2 45 1 4 1 2 false 0.5000000000000001 0.5000000000000001 0.16666666666666674 ribosome_binding GO:0043022 12133 27 45 1 54 1 1 false 0.5000000000000027 0.5000000000000027 5.136266628670832E-16 regulation_of_Ras_GTPase_activity GO:0032318 12133 179 45 1 357 1 2 false 0.5014005602241169 0.5014005602241169 8.083441090582102E-107 regulation_of_MAP_kinase_activity GO:0043405 12133 268 45 1 533 1 3 false 0.5028142589118941 0.5028142589118941 1.0382438249699724E-159 ion_transmembrane_transporter_activity GO:0015075 12133 469 45 3 589 3 2 false 0.5042023369134521 0.5042023369134521 1.1842155919657181E-128 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 45 2 1399 4 3 false 0.5055502323904327 0.5055502323904327 0.0 response_to_peptide_hormone_stimulus GO:0043434 12133 313 45 1 619 1 2 false 0.5056542810985368 0.5056542810985368 1.4916788604957572E-185 negative_regulation_of_apoptotic_process GO:0043066 12133 537 45 2 1377 4 3 false 0.5075209096889128 0.5075209096889128 0.0 protein_polymerization GO:0051258 12133 145 45 1 284 1 1 false 0.5105633802817375 0.5105633802817375 7.244587792673789E-85 catalytic_step_2_spliceosome GO:0071013 12133 76 45 8 151 15 3 false 0.5109247956417549 0.5109247956417549 5.422089502503699E-45 immune_response-regulating_signaling_pathway GO:0002764 12133 310 45 1 3626 8 2 false 0.5111452873247169 0.5111452873247169 0.0 kinetochore GO:0000776 12133 102 45 1 4762 33 4 false 0.5117677466918218 0.5117677466918218 2.0967772168942355E-213 response_to_nitrogen_compound GO:1901698 12133 552 45 2 2369 7 1 false 0.5120172715210006 0.5120172715210006 0.0 reproductive_structure_development GO:0048608 12133 216 45 1 3110 10 3 false 0.5136920558440304 0.5136920558440304 0.0 regulation_of_cell_cycle GO:0051726 12133 659 45 3 6583 27 2 false 0.5164837885059994 0.5164837885059994 0.0 male_gonad_development GO:0008584 12133 84 45 1 162 1 2 false 0.5185185185184836 0.5185185185184836 3.0520910486495067E-48 positive_regulation_of_signaling GO:0023056 12133 817 45 3 4861 16 3 false 0.5195576444267728 0.5195576444267728 0.0 chromatin_modification GO:0016568 12133 458 45 4 539 4 1 false 0.5202927821931725 0.5202927821931725 1.802023694196357E-98 ribonucleoside_biosynthetic_process GO:0042455 12133 124 45 1 1078 6 2 false 0.5204991787620286 0.5204991787620286 2.1378441518501445E-166 ATP_biosynthetic_process GO:0006754 12133 78 45 1 572 5 4 false 0.5208748719821598 0.5208748719821598 2.3320614053513515E-98 U7_snRNP GO:0005683 12133 7 45 1 93 9 1 false 0.5218971620651147 0.5218971620651147 1.0555624376114707E-10 single-stranded_DNA_binding GO:0003697 12133 58 45 2 179 5 1 false 0.5222584897370834 0.5222584897370834 1.7047154028422047E-48 cell_junction_organization GO:0034330 12133 181 45 1 7663 31 2 false 0.5240668209589553 0.5240668209589553 0.0 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 45 1 381 1 2 false 0.52755905511812 0.52755905511812 8.855041133991382E-114 mRNA_3'-UTR_binding GO:0003730 12133 20 45 1 91 3 1 false 0.5295303946989349 0.5295303946989349 1.5304206568397613E-20 cation_transmembrane_transporter_activity GO:0008324 12133 365 45 2 701 3 2 false 0.5310537368441485 0.5310537368441485 5.744660517109641E-210 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 45 10 5462 43 2 false 0.5318219814923482 0.5318219814923482 0.0 MAP_kinase_activity GO:0004707 12133 277 45 1 520 1 2 false 0.5326923076922037 0.5326923076922037 2.5282679507054518E-155 receptor_signaling_protein_activity GO:0005057 12133 339 45 1 1070 2 1 false 0.5334708829110854 0.5334708829110854 2.5248591221043436E-289 tight_junction_assembly GO:0070830 12133 31 45 1 58 1 2 false 0.5344827586206974 0.5344827586206974 3.809192954277456E-17 protein_complex_binding GO:0032403 12133 306 45 2 6397 37 1 false 0.5344852459164677 0.5344852459164677 0.0 defense_response_to_virus GO:0051607 12133 160 45 1 1130 5 3 false 0.5345953935452211 0.5345953935452211 2.076664675339186E-199 enzyme_binding GO:0019899 12133 1005 45 6 6397 37 1 false 0.5357203568110152 0.5357203568110152 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 45 10 5528 43 2 false 0.5362820644524245 0.5362820644524245 0.0 ionotropic_glutamate_receptor_activity GO:0004970 12133 35 45 1 65 1 3 false 0.5384615384615321 0.5384615384615321 3.3232458363084325E-19 fatty_acid_metabolic_process GO:0006631 12133 214 45 1 666 2 2 false 0.5397231818285628 0.5397231818285628 7.544095427296943E-181 histone_methyltransferase_complex GO:0035097 12133 60 45 1 807 10 2 false 0.5402629639236507 0.5402629639236507 3.052234764972827E-92 development_of_primary_male_sexual_characteristics GO:0046546 12133 97 45 1 179 1 2 false 0.5418994413407667 0.5418994413407667 4.0970386268467766E-53 purine_nucleotide_metabolic_process GO:0006163 12133 1208 45 6 1337 6 2 false 0.5433645969325496 0.5433645969325496 1.5771526523631757E-183 myeloid_leukocyte_differentiation GO:0002573 12133 128 45 1 395 2 2 false 0.5436483968385992 0.5436483968385992 2.058300578728218E-107 regulation_of_vesicle-mediated_transport GO:0060627 12133 196 45 1 6585 26 3 false 0.5448594379808548 0.5448594379808548 0.0 poly-pyrimidine_tract_binding GO:0008187 12133 9 45 1 40 3 1 false 0.5450404858299631 0.5450404858299631 3.657124400158464E-9 respiratory_electron_transport_chain GO:0022904 12133 83 45 1 152 1 2 false 0.5460526315789233 0.5460526315789233 5.148701756610971E-45 taxis GO:0042330 12133 488 45 1 1496 2 2 false 0.5461449036903218 0.5461449036903218 0.0 heterocycle_catabolic_process GO:0046700 12133 1243 45 10 5392 43 2 false 0.5468314105722477 0.5468314105722477 0.0 ribonucleoprotein_granule GO:0035770 12133 75 45 1 3365 35 2 false 0.5475024275789182 0.5475024275789182 1.704323678285534E-155 regulation_of_blood_pressure GO:0008217 12133 117 45 1 2120 14 2 false 0.5494556592670881 0.5494556592670881 6.820682324461924E-196 activation_of_MAPK_activity GO:0000187 12133 158 45 1 286 1 2 false 0.5524475524475345 0.5524475524475345 8.207976102051858E-85 aromatic_compound_catabolic_process GO:0019439 12133 1249 45 10 5388 43 2 false 0.554790962471193 0.554790962471193 0.0 actin_filament_polymerization GO:0030041 12133 91 45 1 164 1 2 false 0.5548780487805057 0.5548780487805057 1.838515686014353E-48 steroid_biosynthetic_process GO:0006694 12133 98 45 1 3573 29 3 false 0.5550279539561251 0.5550279539561251 2.291833143174281E-194 regulation_of_cellular_ketone_metabolic_process GO:0010565 12133 133 45 1 3992 24 2 false 0.5576328209500843 0.5576328209500843 1.512735013638228E-252 intracellular_estrogen_receptor_signaling_pathway GO:0030520 12133 34 45 1 102 2 1 false 0.5577557755775552 0.5577557755775552 7.615480469304384E-28 negative_regulation_of_developmental_process GO:0051093 12133 463 45 2 4566 18 3 false 0.5580658225891193 0.5580658225891193 0.0 negative_regulation_of_cell_differentiation GO:0045596 12133 381 45 2 3552 17 4 false 0.5584209645120883 0.5584209645120883 0.0 skeletal_muscle_organ_development GO:0060538 12133 172 45 1 308 1 1 false 0.5584415584415203 0.5584415584415203 3.4535917571053045E-91 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 45 1 442 1 3 false 0.5588235294116876 0.5588235294116876 4.945935388068452E-131 response_to_endogenous_stimulus GO:0009719 12133 982 45 3 5200 15 1 false 0.5592458940855978 0.5592458940855978 0.0 neuron_apoptotic_process GO:0051402 12133 158 45 1 281 1 2 false 0.5622775800711791 0.5622775800711791 4.7762266380223384E-83 positive_regulation_of_cellular_process GO:0048522 12133 2811 45 13 9694 45 3 false 0.5627360921079472 0.5627360921079472 0.0 metal_ion_transport GO:0030001 12133 455 45 2 606 2 1 false 0.5634290701797242 0.5634290701797242 4.665536224038032E-147 meiosis GO:0007126 12133 122 45 1 1243 8 2 false 0.5634774950547374 0.5634774950547374 1.368721434688107E-172 monosaccharide_metabolic_process GO:0005996 12133 217 45 1 385 1 1 false 0.5636363636363345 0.5636363636363345 7.061110236111427E-114 actin_polymerization_or_depolymerization GO:0008154 12133 110 45 1 195 1 1 false 0.5641025641025998 0.5641025641025998 1.7262451149741302E-57 response_to_chemical_stimulus GO:0042221 12133 2369 45 7 5200 15 1 false 0.5653558465018469 0.5653558465018469 0.0 positive_regulation_of_catabolic_process GO:0009896 12133 137 45 1 3517 21 3 false 0.5669124422594294 0.5669124422594294 1.0965595914697655E-250 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 45 22 4395 34 3 false 0.5671255660558439 0.5671255660558439 0.0 regulation_of_developmental_process GO:0050793 12133 1233 45 5 7209 29 2 false 0.5688586581789004 0.5688586581789004 0.0 protein_homodimerization_activity GO:0042803 12133 471 45 3 1035 6 2 false 0.5689774914686936 0.5689774914686936 7.159384282986134E-309 ribonucleotide_metabolic_process GO:0009259 12133 1202 45 6 1318 6 2 false 0.5747195280802102 0.5747195280802102 7.680938106405399E-170 regulation_of_binding GO:0051098 12133 172 45 1 9142 45 2 false 0.5754778058505539 0.5754778058505539 0.0 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 45 1 309 1 2 false 0.5760517799352067 0.5760517799352067 7.558729588417702E-91 ligand-gated_channel_activity GO:0022834 12133 118 45 1 204 1 1 false 0.578431372549022 0.578431372549022 8.558639163508173E-60 sequence-specific_DNA_binding GO:0043565 12133 1189 45 7 2091 12 1 false 0.5796159493536974 0.5796159493536974 0.0 response_to_inorganic_substance GO:0010035 12133 277 45 1 2369 7 1 false 0.581721453033018 0.581721453033018 0.0 skeletal_muscle_tissue_development GO:0007519 12133 168 45 1 288 1 2 false 0.5833333333332881 0.5833333333332881 2.348024843062379E-84 signal_transducer_activity GO:0004871 12133 1070 45 2 3547 6 2 false 0.5835666197086795 0.5835666197086795 0.0 cell-type_specific_apoptotic_process GO:0097285 12133 270 45 1 1373 4 1 false 0.5839414602078256 0.5839414602078256 9.434604867208542E-295 regulation_of_protein_phosphorylation GO:0001932 12133 787 45 3 1444 5 3 false 0.5840613485709915 0.5840613485709915 0.0 response_to_peptide GO:1901652 12133 322 45 1 904 2 2 false 0.5857686766829175 0.5857686766829175 7.8711156655671515E-255 3'-5'_exonuclease_activity GO:0008408 12133 34 45 1 58 1 1 false 0.5862068965517337 0.5862068965517337 7.792892525947503E-17 nuclear_speck GO:0016607 12133 147 45 4 272 7 1 false 0.5888642787861007 0.5888642787861007 6.6218564870724965E-81 amino_acid_binding GO:0016597 12133 110 45 1 186 1 1 false 0.5913978494623976 0.5913978494623976 3.905422178213833E-54 activation_of_protein_kinase_activity GO:0032147 12133 247 45 1 417 1 1 false 0.5923261390887407 0.5923261390887407 9.475379918718814E-122 regulation_of_nucleoside_metabolic_process GO:0009118 12133 308 45 2 3785 24 2 false 0.5931248335695656 0.5931248335695656 0.0 positive_regulation_of_cellular_component_movement GO:0051272 12133 216 45 1 3234 13 3 false 0.5935770950057808 0.5935770950057808 0.0 cellular_ketone_metabolic_process GO:0042180 12133 155 45 1 7667 44 3 false 0.5939166444600285 0.5939166444600285 0.0 erythrocyte_differentiation GO:0030218 12133 88 45 1 243 2 2 false 0.5940890385333677 0.5940890385333677 1.540826297870933E-68 sex_differentiation GO:0007548 12133 202 45 1 340 1 1 false 0.5941176470587681 0.5941176470587681 4.342696063294865E-99 regulation_of_body_fluid_levels GO:0050878 12133 527 45 2 4595 17 2 false 0.5967317183698331 0.5967317183698331 0.0 DNA_metabolic_process GO:0006259 12133 791 45 6 5627 44 2 false 0.5983613111460249 0.5983613111460249 0.0 glycosyl_compound_biosynthetic_process GO:1901659 12133 132 45 1 4856 33 2 false 0.5984825020854289 0.5984825020854289 1.7381228665477006E-262 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 45 20 207 20 1 false 0.5985184735868585 0.5985184735868585 3.3148479610294504E-10 peptidyl-serine_modification GO:0018209 12133 127 45 1 623 4 1 false 0.5992264766801916 0.5992264766801916 3.781982241942545E-136 ATP-dependent_RNA_helicase_activity GO:0004004 12133 20 45 1 99 4 3 false 0.6008631975126484 0.6008631975126484 2.332161908415525E-21 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 45 2 1730 5 2 false 0.6008711111121041 0.6008711111121041 0.0 regulation_of_multi-organism_process GO:0043900 12133 193 45 1 6817 32 2 false 0.6019465584279218 0.6019465584279218 0.0 regulation_of_gene_expression,_epigenetic GO:0040029 12133 120 45 1 2935 22 1 false 0.6021841843079152 0.6021841843079152 6.075348180017095E-217 cellular_response_to_organic_substance GO:0071310 12133 1347 45 5 1979 7 2 false 0.6028826099912697 0.6028826099912697 0.0 N-acyltransferase_activity GO:0016410 12133 79 45 1 131 1 1 false 0.6030534351144949 0.6030534351144949 8.517686978921233E-38 cell_cycle_phase GO:0022403 12133 253 45 1 953 3 1 false 0.6041594581636611 0.6041594581636611 1.0384727319913012E-238 regulation_of_response_to_external_stimulus GO:0032101 12133 314 45 1 2524 7 2 false 0.6059002849909821 0.6059002849909821 0.0 nuclear_pore GO:0005643 12133 69 45 1 2781 37 3 false 0.6077057751712713 0.6077057751712713 8.971129873692015E-140 estrogen_receptor_binding GO:0030331 12133 23 45 1 62 2 1 false 0.6081438392385131 0.6081438392385131 1.6756493074771417E-17 purine_nucleotide_catabolic_process GO:0006195 12133 956 45 5 1223 6 3 false 0.6103320141827606 0.6103320141827606 6.80299167777575E-278 acetyltransferase_activity GO:0016407 12133 80 45 1 131 1 1 false 0.6106870229007448 0.6106870229007448 1.3104133813724972E-37 transcription_factor_complex GO:0005667 12133 266 45 2 3138 24 2 false 0.6164253723007516 0.6164253723007516 0.0 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 45 7 5303 31 3 false 0.6180858614517994 0.6180858614517994 0.0 covalent_chromatin_modification GO:0016569 12133 312 45 3 458 4 1 false 0.6185434585864209 0.6185434585864209 7.826311589520491E-124 establishment_of_protein_localization GO:0045184 12133 1153 45 6 3010 16 2 false 0.6194746034162397 0.6194746034162397 0.0 regulation_of_nucleotide_biosynthetic_process GO:0030808 12133 146 45 1 3406 22 3 false 0.6197403792925174 0.6197403792925174 5.390613252169377E-261 glycosyl_compound_metabolic_process GO:1901657 12133 1093 45 6 7599 44 2 false 0.621869086038593 0.621869086038593 0.0 nucleoside_biosynthetic_process GO:0009163 12133 132 45 1 4282 31 5 false 0.6224825043348841 0.6224825043348841 3.6074601902532293E-255 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 45 1 252 1 2 false 0.6230158730158346 0.6230158730158346 5.925442745937436E-72 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 45 5 1202 6 3 false 0.6234256527068106 0.6234256527068106 1.616697592155103E-269 cellular_component_organization GO:0016043 12133 3745 45 19 3839 19 1 false 0.6236678377274834 0.6236678377274834 4.153510440731863E-191 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 45 12 6129 44 3 false 0.6237152046613623 0.6237152046613623 0.0 ligase_activity GO:0016874 12133 504 45 1 4901 9 1 false 0.6237471819324355 0.6237471819324355 0.0 response_to_hypoxia GO:0001666 12133 200 45 1 2540 12 2 false 0.6270778934915058 0.6270778934915058 2.6634431659671552E-303 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 45 4 3771 20 4 false 0.6283924345899932 0.6283924345899932 0.0 cell_motility GO:0048870 12133 785 45 1 1249 1 3 false 0.6285028022420741 0.6285028022420741 0.0 carbohydrate_biosynthetic_process GO:0016051 12133 132 45 1 4212 31 2 false 0.6286640601927063 0.6286640601927063 3.288354819591378E-254 regulation_of_biological_process GO:0050789 12133 6622 45 28 10446 45 2 false 0.6294109825470802 0.6294109825470802 0.0 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 45 10 4878 42 5 false 0.6302557244577818 0.6302557244577818 0.0 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 45 2 5051 10 3 false 0.6320377567553257 0.6320377567553257 0.0 U5_snRNP GO:0005682 12133 80 45 8 93 9 1 false 0.6328920783325254 0.6328920783325254 3.852654648545616E-16 protein-DNA_complex GO:0032993 12133 110 45 1 3462 31 1 false 0.6341023810951751 0.6341023810951751 4.3156565695482125E-211 cellular_response_to_peptide GO:1901653 12133 247 45 1 625 2 3 false 0.6346000000000278 0.6346000000000278 2.2359681686760748E-181 mitochondrion_organization GO:0007005 12133 215 45 1 2031 9 1 false 0.6354650233131169 0.6354650233131169 4.082912305313268E-297 PML_body GO:0016605 12133 77 45 2 272 7 1 false 0.6365611953426293 0.6365611953426293 7.662735942565743E-70 apical_junction_assembly GO:0043297 12133 37 45 1 58 1 1 false 0.6379310344827669 0.6379310344827669 2.991639077401756E-16 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 45 22 6094 43 2 false 0.6384487081718254 0.6384487081718254 0.0 regulation_of_actin_filament_length GO:0030832 12133 90 45 1 226 2 2 false 0.6389380530973381 0.6389380530973381 1.910049666821174E-65 muscle_organ_development GO:0007517 12133 308 45 1 1966 6 2 false 0.6407562046309138 0.6407562046309138 0.0 chromosome,_centromeric_region GO:0000775 12133 148 45 1 512 3 1 false 0.6415277497983706 0.6415277497983706 5.05623540709124E-133 divalent_inorganic_cation_transport GO:0072511 12133 243 45 1 606 2 1 false 0.6415841584161986 0.6415841584161986 1.781632444658852E-176 RNA_biosynthetic_process GO:0032774 12133 2751 45 27 4191 42 3 false 0.6417979087805927 0.6417979087805927 0.0 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 45 5 1541 17 3 false 0.6426352039982932 0.6426352039982932 0.0 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 45 2 202 20 1 false 0.6443185844324255 0.6443185844324255 5.801734415928739E-29 ATP-dependent_DNA_helicase_activity GO:0004003 12133 32 45 1 142 4 3 false 0.6443879871914913 0.6443879871914913 1.5505006270676482E-32 leukocyte_differentiation GO:0002521 12133 299 45 1 2177 7 2 false 0.6450299733336113 0.6450299733336113 0.0 actin_cytoskeleton GO:0015629 12133 327 45 1 1430 4 1 false 0.646477821928872 0.646477821928872 0.0 regulation_of_Ras_protein_signal_transduction GO:0046578 12133 270 45 1 417 1 2 false 0.6474820143884905 0.6474820143884905 7.174398789465976E-117 wound_healing GO:0042060 12133 543 45 2 905 3 1 false 0.6481595272399266 0.6481595272399266 1.120707554751266E-263 blood_coagulation GO:0007596 12133 443 45 2 550 2 3 false 0.6484716012585028 0.6484716012585028 4.662213706291943E-117 nucleic_acid_transport GO:0050657 12133 124 45 5 135 5 1 false 0.6494082610727934 0.6494082610727934 2.2345648964967124E-16 positive_regulation_of_defense_response_to_virus_by_host GO:0002230 12133 13 45 1 20 1 1 false 0.6500000000000001 0.6500000000000001 1.2899896800825618E-5 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 45 2 1356 5 2 false 0.650031361290332 0.650031361290332 0.0 regulation_of_small_GTPase_mediated_signal_transduction GO:0051056 12133 335 45 1 1759 5 2 false 0.6527527588203688 0.6527527588203688 0.0 nuclear_chromatin GO:0000790 12133 151 45 1 368 2 2 false 0.6529439639853226 0.6529439639853226 1.5117378626822706E-107 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 45 1 1813 3 1 false 0.6597510000674004 0.6597510000674004 0.0 regulation_of_metal_ion_transport GO:0010959 12133 159 45 1 527 3 2 false 0.6603439884478202 0.6603439884478202 1.9143009234930405E-139 DNA-dependent_transcription,_initiation GO:0006352 12133 225 45 2 2751 27 2 false 0.6613278749019309 0.6613278749019309 0.0 cell_body GO:0044297 12133 239 45 1 9983 45 1 false 0.6647493550094821 0.6647493550094821 0.0 age-dependent_telomere_shortening GO:0001309 12133 2 45 1 3 1 2 false 0.6666666666666667 0.6666666666666667 0.33333333333333337 RNA_polymerase_core_enzyme_binding GO:0043175 12133 10 45 1 15 1 1 false 0.6666666666666671 0.6666666666666671 3.330003330003327E-4 calcium_ion_transmembrane_transporter_activity GO:0015085 12133 117 45 1 277 2 3 false 0.6672421911787834 0.6672421911787834 2.4235660306174516E-81 Ras_protein_signal_transduction GO:0007265 12133 365 45 1 547 1 1 false 0.667276051188237 0.667276051188237 2.1494674666292624E-150 single-organism_developmental_process GO:0044767 12133 2776 45 9 8064 28 2 false 0.6685148475628935 0.6685148475628935 0.0 nucleoplasm_part GO:0044451 12133 805 45 10 2767 37 2 false 0.6699782093851422 0.6699782093851422 0.0 mRNA_binding GO:0003729 12133 91 45 3 763 28 1 false 0.670027093302416 0.670027093302416 1.7788235024198917E-120 cellular_response_to_insulin_stimulus GO:0032869 12133 185 45 1 276 1 2 false 0.6702898550724703 0.6702898550724703 1.999097443178639E-75 cytokine_production GO:0001816 12133 362 45 1 4095 12 1 false 0.6711719197242241 0.6711719197242241 0.0 regulation_of_actin_filament_polymerization GO:0030833 12133 80 45 1 119 1 3 false 0.6722689075630337 0.6722689075630337 2.6187871314203243E-32 cellular_carbohydrate_metabolic_process GO:0044262 12133 183 45 1 7315 44 2 false 0.6730952412731559 0.6730952412731559 0.0 cardiovascular_system_development GO:0072358 12133 655 45 1 2686 4 2 false 0.6733350968058435 0.6733350968058435 0.0 circulatory_system_development GO:0072359 12133 655 45 1 2686 4 1 false 0.6733350968058435 0.6733350968058435 0.0 regulation_of_protein_polymerization GO:0032271 12133 99 45 1 231 2 2 false 0.6745341614905945 0.6745341614905945 5.823008262858585E-68 heart_process GO:0003015 12133 132 45 1 307 2 1 false 0.6758638308742387 0.6758638308742387 1.7124819377000923E-90 heart_contraction GO:0060047 12133 132 45 1 307 2 2 false 0.6758638308742387 0.6758638308742387 1.7124819377000923E-90 intracellular_signal_transduction GO:0035556 12133 1813 45 3 3547 6 1 false 0.6770346240497745 0.6770346240497745 0.0 calcium_channel_activity GO:0005262 12133 104 45 1 241 2 3 false 0.6778699861688137 0.6778699861688137 5.2662088963328235E-71 programmed_cell_death GO:0012501 12133 1385 45 4 1525 4 1 false 0.6800591999761461 0.6800591999761461 2.142172117700311E-202 regulation_of_GTP_catabolic_process GO:0033124 12133 279 45 1 642 2 3 false 0.6806829282517377 0.6806829282517377 4.2701237450964594E-190 cell_cycle_process GO:0022402 12133 953 45 3 7541 27 2 false 0.6813695470456307 0.6813695470456307 0.0 response_to_oxygen_levels GO:0070482 12133 214 45 1 676 3 1 false 0.6814406420890696 0.6814406420890696 1.6255941364061853E-182 response_to_metal_ion GO:0010038 12133 189 45 1 277 1 1 false 0.6823104693141068 0.6823104693141068 1.2236423246824455E-74 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 45 2 1804 7 2 false 0.6824469438535037 0.6824469438535037 0.0 cell_leading_edge GO:0031252 12133 252 45 1 9983 45 1 false 0.6843401316558565 0.6843401316558565 0.0 receptor_activity GO:0004872 12133 790 45 3 10257 45 1 false 0.684413797358776 0.684413797358776 0.0 regulation_of_catabolic_process GO:0009894 12133 554 45 3 5455 34 2 false 0.6858706775242136 0.6858706775242136 0.0 regulation_of_cytokine_production GO:0001817 12133 323 45 1 1562 5 2 false 0.6865090704865826 0.6865090704865826 0.0 interaction_with_host GO:0051701 12133 387 45 5 417 5 2 false 0.6871651445785305 0.6871651445785305 1.9217516081652173E-46 ribose_phosphate_biosynthetic_process GO:0046390 12133 279 45 1 1586 6 3 false 0.6874241817099958 0.6874241817099958 1.5665E-319 response_to_insulin_stimulus GO:0032868 12133 216 45 1 313 1 1 false 0.6900958466453341 0.6900958466453341 1.4650294580642456E-83 mRNA_3'-end_processing GO:0031124 12133 86 45 5 386 25 2 false 0.6914697492776135 0.6914697492776135 2.4694341980396157E-88 small-subunit_processome GO:0032040 12133 6 45 1 14 2 1 false 0.6923076923076915 0.6923076923076915 3.330003330003332E-4 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 45 1 541 2 2 false 0.6929554323269613 0.6929554323269613 1.01164377942614E-160 anatomical_structure_development GO:0048856 12133 3099 45 10 3447 11 1 false 0.6932713698272199 0.6932713698272199 0.0 response_to_salt_stress GO:0009651 12133 19 45 1 43 2 1 false 0.694352159468437 0.694352159468437 1.2492622608986976E-12 proteolysis GO:0006508 12133 732 45 3 3431 16 1 false 0.6959683389022753 0.6959683389022753 0.0 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 45 1 5033 19 3 false 0.6969898657205746 0.6969898657205746 0.0 cell_differentiation GO:0030154 12133 2154 45 7 2267 7 1 false 0.6987917792378382 0.6987917792378382 2.602261335719434E-194 protein_serine/threonine_kinase_activity GO:0004674 12133 709 45 1 1014 1 1 false 0.6992110453650483 0.6992110453650483 1.8231541307779663E-268 double-stranded_DNA_binding GO:0003690 12133 109 45 3 179 5 1 false 0.7000020649529881 0.7000020649529881 1.5496409193142626E-51 regulation_of_membrane_potential GO:0042391 12133 216 45 1 478 2 1 false 0.7000868398201406 0.7000868398201406 3.2092050959317294E-142 chromatin_organization GO:0006325 12133 539 45 4 689 5 1 false 0.7008646561145457 0.7008646561145457 4.375882251809235E-156 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 45 2 5830 20 3 false 0.7014006175119554 0.7014006175119554 0.0 regulation_of_mRNA_stability GO:0043488 12133 33 45 3 37 3 1 false 0.7021879021879068 0.7021879021879068 1.5141191611779804E-5 negative_regulation_of_signal_transduction GO:0009968 12133 571 45 1 3588 7 5 false 0.7031217238420311 0.7031217238420311 0.0 nuclear_envelope GO:0005635 12133 258 45 2 3962 37 3 false 0.7052334796911853 0.7052334796911853 0.0 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 45 1 2943 14 3 false 0.7062074482542715 0.7062074482542715 0.0 cellular_metal_ion_homeostasis GO:0006875 12133 259 45 2 308 2 2 false 0.7066923304706553 0.7066923304706553 3.9623191237847456E-58 inflammatory_response GO:0006954 12133 381 45 1 1437 4 2 false 0.7088122508081162 0.7088122508081162 0.0 cellular_response_to_organic_nitrogen GO:0071417 12133 323 45 1 1478 5 4 false 0.7091198320044863 0.7091198320044863 0.0 metal_ion_homeostasis GO:0055065 12133 278 45 2 330 2 1 false 0.7092751220410046 0.7092751220410046 6.131976736615521E-62 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 45 3 1779 4 1 false 0.7093826649910489 0.7093826649910489 0.0 negative_regulation_of_transport GO:0051051 12133 243 45 1 4618 23 3 false 0.71243965426487 0.71243965426487 0.0 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 45 2 1384 17 2 false 0.7152439297576337 0.7152439297576337 1.3395090025049634E-243 hemostasis GO:0007599 12133 447 45 2 527 2 1 false 0.7191939452097564 0.7191939452097564 7.174896528140087E-97 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 45 3 645 3 1 false 0.7192329577808879 0.7192329577808879 7.3138241320053254E-93 cellular_response_to_glucose_stimulus GO:0071333 12133 47 45 1 100 2 3 false 0.7216161616161718 0.7216161616161718 1.1846448146925151E-29 endonucleolytic_cleavage_in_ITS1_to_separate_SSU-rRNA_from_5.8S_rRNA_and_LSU-rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000447 12133 4 45 1 9 2 3 false 0.7222222222222212 0.7222222222222212 0.007936507936507922 organophosphate_catabolic_process GO:0046434 12133 1000 45 5 2495 14 2 false 0.7234349742703508 0.7234349742703508 0.0 regulation_of_response_to_stimulus GO:0048583 12133 2074 45 7 7292 28 2 false 0.7236514125258102 0.7236514125258102 0.0 homeostasis_of_number_of_cells GO:0048872 12133 166 45 1 990 7 1 false 0.7244634273054049 0.7244634273054049 1.128853988781411E-193 cellular_response_to_stimulus GO:0051716 12133 4236 45 14 7871 28 2 false 0.7250019592569725 0.7250019592569725 0.0 nuclear_hormone_receptor_binding GO:0035257 12133 104 45 2 122 2 1 false 0.7256469313101672 0.7256469313101672 6.677251530520905E-22 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 45 2 1211 6 2 false 0.7262630714498959 0.7262630714498959 0.0 cytosolic_calcium_ion_homeostasis GO:0051480 12133 149 45 1 205 1 1 false 0.726829268292646 0.726829268292646 9.962188539004893E-52 monovalent_inorganic_cation_transmembrane_transporter_activity GO:0015077 12133 198 45 1 413 2 2 false 0.7296010719577959 0.7296010719577959 1.708187099767858E-123 Cajal_body GO:0015030 12133 46 45 1 272 7 1 false 0.7309519575702558 0.7309519575702558 3.189172863463676E-53 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 45 9 7638 44 4 false 0.7320522049725263 0.7320522049725263 0.0 protein_acetylation GO:0006473 12133 140 45 3 155 3 1 false 0.7353228681501589 0.7353228681501589 3.675799410957308E-21 poly-purine_tract_binding GO:0070717 12133 14 45 1 40 3 1 false 0.7368421052631625 0.7368421052631625 4.309057712047628E-11 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 45 1 442 2 3 false 0.7414350355528618 0.7414350355528618 2.4953498472018727E-132 cellular_developmental_process GO:0048869 12133 2267 45 7 7817 28 2 false 0.744872048690087 0.744872048690087 0.0 histone_H4_acetylation GO:0043967 12133 44 45 1 121 3 1 false 0.7459893048128603 0.7459893048128603 4.76799917217802E-34 N-acetyltransferase_activity GO:0008080 12133 68 45 1 91 1 2 false 0.747252747252751 0.747252747252751 4.74214851415134E-22 single-organism_carbohydrate_metabolic_process GO:0044723 12133 385 45 1 515 1 1 false 0.7475728155339276 0.7475728155339276 1.0653300741927565E-125 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 45 1 639 2 3 false 0.748038912682166 0.748038912682166 1.399157780258238E-191 monovalent_inorganic_cation_transport GO:0015672 12133 302 45 1 606 2 1 false 0.748760330578956 0.748760330578956 1.1660817479890875E-181 inorganic_cation_transmembrane_transporter_activity GO:0022890 12133 316 45 2 365 2 1 false 0.7492096944151887 0.7492096944151887 4.982755146780477E-62 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 45 2 4239 24 3 false 0.7495997282324524 0.7495997282324524 0.0 transcription_coactivator_activity GO:0003713 12133 264 45 3 478 6 2 false 0.7498476044696977 0.7498476044696977 4.798051856605128E-142 maturation_of_SSU-rRNA_from_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000462 12133 7 45 2 8 2 1 false 0.7500000000000001 0.7500000000000001 0.12499999999999997 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 45 2 3799 42 1 false 0.7502015675495082 0.7502015675495082 0.0 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 45 5 2517 14 2 false 0.7504719369476486 0.7504719369476486 0.0 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 45 1 504 1 1 false 0.7519841269840213 0.7519841269840213 6.011520399617331E-122 chromosomal_part GO:0044427 12133 512 45 3 5337 40 2 false 0.752765065205275 0.752765065205275 0.0 anion_binding GO:0043168 12133 2280 45 5 4448 11 1 false 0.7535258484571147 0.7535258484571147 0.0 spliceosomal_snRNP_assembly GO:0000387 12133 30 45 2 259 22 2 false 0.7543637391381208 0.7543637391381208 6.073894661120439E-40 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 45 3 3547 6 1 false 0.7560588664535783 0.7560588664535783 0.0 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 45 1 1112 3 4 false 0.7562550173939411 0.7562550173939411 1.302733E-318 double-strand_break_repair GO:0006302 12133 109 45 1 368 4 1 false 0.7563285060808744 0.7563285060808744 1.714085470943145E-96 substrate-specific_transmembrane_transporter_activity GO:0022891 12133 502 45 3 660 4 2 false 0.7564033419186302 0.7564033419186302 4.8010140095396714E-157 ion_transport GO:0006811 12133 833 45 3 2323 10 1 false 0.7571018377735741 0.7571018377735741 0.0 regulatory_region_DNA_binding GO:0000975 12133 1169 45 6 2091 12 2 false 0.7605149444220171 0.7605149444220171 0.0 steroid_metabolic_process GO:0008202 12133 182 45 1 5438 42 2 false 0.7619407746662259 0.7619407746662259 0.0 response_to_organic_substance GO:0010033 12133 1783 45 5 2369 7 1 false 0.762092322366978 0.762092322366978 0.0 histone_mRNA_metabolic_process GO:0008334 12133 27 45 1 573 29 1 false 0.7621254261037765 0.7621254261037765 6.871324608301151E-47 purine_nucleotide_biosynthetic_process GO:0006164 12133 269 45 1 1265 6 3 false 0.7625252483902081 0.7625252483902081 1.9379490968147627E-283 internal_protein_amino_acid_acetylation GO:0006475 12133 128 45 3 140 3 1 false 0.7627150453549966 0.7627150453549966 1.3721041217101573E-17 negative_regulation_of_cell_death GO:0060548 12133 567 45 2 3054 14 3 false 0.7642406130234449 0.7642406130234449 0.0 histone_acetyltransferase_activity GO:0004402 12133 52 45 1 137 3 2 false 0.7643957826439874 0.7643957826439874 4.532765208696966E-39 biological_regulation GO:0065007 12133 6908 45 28 10446 45 1 false 0.7644897072844306 0.7644897072844306 0.0 cell_junction_assembly GO:0034329 12133 159 45 1 1406 12 2 false 0.7645172960901837 0.7645172960901837 9.423437086545545E-215 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 45 6 2877 22 6 false 0.7663152027044037 0.7663152027044037 0.0 nuclear_membrane GO:0031965 12133 157 45 1 4084 37 3 false 0.7670662507427211 0.7670662507427211 2.8056123615014062E-288 peptidyl-tyrosine_modification GO:0018212 12133 191 45 1 623 4 1 false 0.7697895447325441 0.7697895447325441 5.019013158282893E-166 cellular_response_to_hormone_stimulus GO:0032870 12133 384 45 1 1510 5 3 false 0.769949021627118 0.769949021627118 0.0 divalent_metal_ion_transport GO:0070838 12133 237 45 1 455 2 2 false 0.7709928837685269 0.7709928837685269 4.2718300435394164E-136 DNA_helicase_activity GO:0003678 12133 45 45 1 147 4 2 false 0.7724084910298401 0.7724084910298401 6.658599492091069E-39 histone_H3_acetylation GO:0043966 12133 47 45 1 121 3 1 false 0.7749010347941183 0.7749010347941183 1.0569119149264125E-34 purine_ribonucleotide_biosynthetic_process GO:0009152 12133 265 45 1 1206 6 3 false 0.7751321315136926 0.7751321315136926 5.7559641067065754E-275 ribonucleotide_biosynthetic_process GO:0009260 12133 275 45 1 1250 6 3 false 0.7755638769665476 0.7755638769665476 3.3374763917028038E-285 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 45 7 5558 42 3 false 0.7758283436024984 0.7758283436024984 0.0 defense_response GO:0006952 12133 1018 45 4 2540 12 1 false 0.7769237410398824 0.7769237410398824 0.0 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 45 1 2035 9 3 false 0.7771091045720074 0.7771091045720074 0.0 negative_regulation_of_cell_cycle GO:0045786 12133 298 45 1 3131 15 3 false 0.7777122134101359 0.7777122134101359 0.0 DNA-dependent_ATPase_activity GO:0008094 12133 71 45 1 228 4 1 false 0.7778608998293051 0.7778608998293051 6.772142656773899E-61 transport GO:0006810 12133 2783 45 14 2833 14 1 false 0.7788994684404359 0.7788994684404359 1.147202604491021E-108 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 45 5 106 5 2 false 0.7816070684054375 0.7816070684054375 9.867686559172291E-9 protein_domain_specific_binding GO:0019904 12133 486 45 2 6397 37 1 false 0.7836254713776923 0.7836254713776923 0.0 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 45 1 673 2 2 false 0.7854489492677783 0.7854489492677783 4.9348138289436974E-201 cellular_membrane_organization GO:0016044 12133 784 45 2 7541 27 2 false 0.7872193238691259 0.7872193238691259 0.0 regulation_of_response_to_stress GO:0080134 12133 674 45 2 3466 14 2 false 0.788426984842075 0.788426984842075 0.0 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 45 5 2643 14 2 false 0.7899447386972327 0.7899447386972327 0.0 response_to_oxygen-containing_compound GO:1901700 12133 864 45 2 2369 7 1 false 0.790802035356762 0.790802035356762 0.0 phosphorylation GO:0016310 12133 1421 45 3 2776 7 1 false 0.7927752875840228 0.7927752875840228 0.0 intrinsic_to_membrane GO:0031224 12133 2375 45 1 2995 1 1 false 0.792988313854418 0.792988313854418 0.0 cellular_response_to_nitrogen_compound GO:1901699 12133 347 45 1 1721 7 2 false 0.7938900811394496 0.7938900811394496 0.0 envelope GO:0031975 12133 641 45 2 9983 45 1 false 0.7943604266582721 0.7943604266582721 0.0 cation_binding GO:0043169 12133 2758 45 6 4448 11 1 false 0.7961079989449412 0.7961079989449412 0.0 negative_regulation_of_protein_modification_process GO:0031400 12133 328 45 1 2431 11 3 false 0.7976700415270926 0.7976700415270926 0.0 ligand-gated_ion_channel_activity GO:0015276 12133 118 45 1 286 3 3 false 0.79881082594204 0.79881082594204 1.3590920268081467E-83 regulation_of_mRNA_splicing,_via_spliceosome GO:0048024 12133 32 45 2 231 20 3 false 0.7994736213575722 0.7994736213575722 5.789429371590664E-40 protection_from_non-homologous_end_joining_at_telomere GO:0031848 12133 4 45 1 5 1 2 false 0.7999999999999997 0.7999999999999997 0.19999999999999996 perinuclear_region_of_cytoplasm GO:0048471 12133 416 45 1 5117 19 1 false 0.800916941708657 0.800916941708657 0.0 chemotaxis GO:0006935 12133 488 45 1 2369 7 2 false 0.8014978131418949 0.8014978131418949 0.0 regulation_of_actin_polymerization_or_depolymerization GO:0008064 12133 89 45 1 111 1 2 false 0.8018018018017868 0.8018018018017868 1.0524930806279637E-23 cell_division GO:0051301 12133 438 45 1 7541 27 1 false 0.8018025469712393 0.8018025469712393 0.0 protein_transport GO:0015031 12133 1099 45 6 1627 10 2 false 0.8052089183055873 0.8052089183055873 0.0 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 45 2 982 3 1 false 0.8052164321323856 0.8052164321323856 2.6984349291053464E-253 death GO:0016265 12133 1528 45 4 8052 28 1 false 0.8061388183437151 0.8061388183437151 0.0 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 45 7 3631 42 4 false 0.8066142777472012 0.8066142777472012 0.0 regulation_of_nucleotide_catabolic_process GO:0030811 12133 306 45 1 1279 6 3 false 0.8068713872237524 0.8068713872237524 9.116385096369177E-305 ionotropic_glutamate_receptor_signaling_pathway GO:0035235 12133 38 45 1 47 1 1 false 0.808510638297866 0.808510638297866 7.338646222098485E-10 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 45 5 6622 28 1 false 0.8104538265493613 0.8104538265493613 0.0 purine_nucleoside_catabolic_process GO:0006152 12133 939 45 5 1085 6 3 false 0.812474742301533 0.812474742301533 2.1746006434797338E-185 DNA-directed_RNA_polymerase_II,_holoenzyme GO:0016591 12133 124 45 1 809 10 2 false 0.8124963163123412 0.8124963163123412 8.164850025378603E-150 glycosyl_compound_catabolic_process GO:1901658 12133 956 45 5 2175 14 2 false 0.8130722310707115 0.8130722310707115 0.0 activation_of_innate_immune_response GO:0002218 12133 155 45 1 362 3 2 false 0.81418825852076 0.81418825852076 1.0665156090103768E-106 actin_filament_organization GO:0007015 12133 195 45 1 1147 9 2 false 0.8142818119753246 0.8142818119753246 2.5334935844901407E-226 nucleotide_biosynthetic_process GO:0009165 12133 322 45 1 1318 6 2 false 0.8144502130323884 0.8144502130323884 2.1862113E-317 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 45 22 5532 43 4 false 0.8151334391282188 0.8151334391282188 0.0 DNA_conformation_change GO:0071103 12133 194 45 1 791 6 1 false 0.8163054261914755 0.8163054261914755 1.3022788504353465E-190 cation_transport GO:0006812 12133 606 45 2 833 3 1 false 0.8180159560354237 0.8180159560354237 4.047492354513465E-211 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 45 5 181 5 1 false 0.8191651174969621 0.8191651174969621 8.905994863592909E-13 regulation_of_anatomical_structure_size GO:0090066 12133 256 45 1 2082 13 1 false 0.819295177267355 0.819295177267355 0.0 regulation_of_cellular_component_movement GO:0051270 12133 412 45 1 6475 26 3 false 0.8196328812854141 0.8196328812854141 0.0 regulation_of_cell_cycle_process GO:0010564 12133 382 45 1 1096 4 2 false 0.8204128829347301 0.8204128829347301 7.137372224746455E-307 ion_gated_channel_activity GO:0022839 12133 204 45 1 469 3 2 false 0.8204977184808485 0.8204977184808485 9.436824095674645E-139 regulation_of_cell_development GO:0060284 12133 446 45 1 1519 5 2 false 0.8246044782232831 0.8246044782232831 0.0 cell_death GO:0008219 12133 1525 45 4 7542 27 2 false 0.825385120995608 0.825385120995608 0.0 regulation_of_alternative_mRNA_splicing,_via_spliceosome GO:0000381 12133 16 45 1 37 3 2 false 0.8288288288288314 0.8288288288288314 7.76652299088412E-11 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 45 7 5151 42 4 false 0.8298257594672431 0.8298257594672431 0.0 regulation_of_protein_localization GO:0032880 12133 349 45 1 2148 10 2 false 0.8308787872937301 0.8308787872937301 0.0 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 45 6 2528 17 3 false 0.8335683475619025 0.8335683475619025 0.0 developmental_process_involved_in_reproduction GO:0003006 12133 340 45 1 3959 20 2 false 0.8347670207259337 0.8347670207259337 0.0 nuclear_chromosome_part GO:0044454 12133 244 45 2 2878 37 3 false 0.834871342614785 0.834871342614785 0.0 response_to_external_stimulus GO:0009605 12133 1046 45 2 5200 15 1 false 0.8359195706348628 0.8359195706348628 0.0 lipid_metabolic_process GO:0006629 12133 769 45 3 7599 44 3 false 0.8366588734270155 0.8366588734270155 0.0 multicellular_organismal_development GO:0007275 12133 3069 45 8 4373 13 2 false 0.8386338243755858 0.8386338243755858 0.0 cell_surface GO:0009986 12133 396 45 1 9983 45 1 false 0.8388649055193411 0.8388649055193411 0.0 transferase_activity,_transferring_acyl_groups_other_than_amino-acyl_groups GO:0016747 12133 131 45 1 156 1 1 false 0.8397435897435931 0.8397435897435931 1.7588456795479544E-29 cell-cell_junction_organization GO:0045216 12133 152 45 1 181 1 1 false 0.8397790055249296 0.8397790055249296 3.1886200066761254E-34 positive_regulation_of_molecular_function GO:0044093 12133 1303 45 4 10257 45 2 false 0.8407647941713999 0.8407647941713999 0.0 virus-host_interaction GO:0019048 12133 355 45 5 588 10 2 false 0.8419619448949766 0.8419619448949766 1.0104535019427035E-170 small_molecule_metabolic_process GO:0044281 12133 2423 45 7 2877 9 1 false 0.8423490185516569 0.8423490185516569 0.0 regulation_of_hydrolase_activity GO:0051336 12133 821 45 1 3094 6 2 false 0.8430673917455678 0.8430673917455678 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 45 3 400 3 2 false 0.8435387463631769 0.8435387463631769 1.150456419433401E-36 chromosome GO:0005694 12133 592 45 3 3226 24 1 false 0.844288364551153 0.844288364551153 0.0 response_to_monosaccharide_stimulus GO:0034284 12133 98 45 1 116 1 1 false 0.8448275862069218 0.8448275862069218 1.7787368796427923E-21 regulation_of_localization GO:0032879 12133 1242 45 4 7621 35 2 false 0.8450934947820926 0.8450934947820926 0.0 protein_dimerization_activity GO:0046983 12133 779 45 3 6397 37 1 false 0.8456562530572015 0.8456562530572015 0.0 cellular_protein_complex_disassembly GO:0043624 12133 149 45 5 154 5 1 false 0.8459841583156823 0.8459841583156823 1.4793035521715585E-9 internal_peptidyl-lysine_acetylation GO:0018393 12133 124 45 3 131 3 2 false 0.8469977741058898 0.8469977741058898 8.960493506706349E-12 nuclear_DNA-directed_RNA_polymerase_complex GO:0055029 12133 136 45 1 2767 37 2 false 0.8470040831797019 0.8470040831797019 8.223970221232538E-235 mRNA_transport GO:0051028 12133 106 45 4 124 5 1 false 0.8472541668483583 0.8472541668483583 4.872659948511352E-22 immune_system_process GO:0002376 12133 1618 45 5 10446 45 1 false 0.84736521773067 0.84736521773067 0.0 regulation_of_multicellular_organismal_development GO:2000026 12133 953 45 2 3481 11 3 false 0.8478991758894155 0.8478991758894155 0.0 ribonucleoside_catabolic_process GO:0042454 12133 946 45 5 1073 6 2 false 0.8483117236043369 0.8483117236043369 9.25790942536024E-169 androgen_receptor_signaling_pathway GO:0030521 12133 62 45 1 102 2 1 false 0.8485730926033468 0.8485730926033468 2.6706454874295595E-29 positive_regulation_of_cell_differentiation GO:0045597 12133 439 45 1 3709 15 4 false 0.8494403430671982 0.8494403430671982 0.0 single-multicellular_organism_process GO:0044707 12133 4095 45 12 8057 28 2 false 0.8494800900052887 0.8494800900052887 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 45 1 701 2 2 false 0.8497819441612448 0.8497819441612448 1.5434745144062482E-202 transmembrane_signaling_receptor_activity GO:0004888 12133 539 45 1 633 1 1 false 0.8515007898894003 0.8515007898894003 7.293829448224349E-115 protein_ubiquitination GO:0016567 12133 548 45 3 578 3 1 false 0.8519897942868612 0.8519897942868612 7.913703273197485E-51 chemical_homeostasis GO:0048878 12133 677 45 4 990 7 1 false 0.8528410389624927 0.8528410389624927 1.9931274413677286E-267 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 45 5 1054 6 2 false 0.8538987797871762 0.8538987797871762 2.3625686453162704E-163 androgen_receptor_binding GO:0050681 12133 38 45 1 62 2 1 false 0.8540454785827765 0.8540454785827765 1.0311688046013243E-17 erythrocyte_homeostasis GO:0034101 12133 95 45 1 111 1 1 false 0.8558558558558544 0.8558558558558544 1.225965890705918E-19 striated_muscle_cell_differentiation GO:0051146 12133 203 45 2 267 3 1 false 0.8562511855215267 0.8562511855215267 2.4098375851666058E-63 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 45 5 1060 6 3 false 0.8572839855249366 0.8572839855249366 8.715047292960447E-163 MAPK_cascade GO:0000165 12133 502 45 1 806 2 1 false 0.8580336914137126 0.8580336914137126 3.7900857366173457E-231 cell_proliferation GO:0008283 12133 1316 45 3 8052 28 1 false 0.8591816169085706 0.8591816169085706 0.0 response_to_wounding GO:0009611 12133 905 45 3 2540 12 1 false 0.8595943371844506 0.8595943371844506 0.0 protein_oligomerization GO:0051259 12133 288 45 1 743 4 1 false 0.8600859784869808 0.8600859784869808 1.196705520432063E-214 regulation_of_purine_nucleotide_catabolic_process GO:0033121 12133 305 45 1 1088 6 3 false 0.8618167303416443 0.8618167303416443 1.7563474810306042E-279 positive_regulation_of_gene_expression GO:0010628 12133 1008 45 8 4103 43 3 false 0.8641136359031378 0.8641136359031378 0.0 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 45 6 4456 31 4 false 0.8643348212828044 0.8643348212828044 0.0 male_germ_cell_nucleus GO:0001673 12133 13 45 1 15 1 1 false 0.8666666666666659 0.8666666666666659 0.009523809523809518 regulation_of_cellular_process GO:0050794 12133 6304 45 26 9757 45 2 false 0.8673948099839083 0.8673948099839083 0.0 protein_phosphorylation GO:0006468 12133 1195 45 3 2577 9 2 false 0.8694503719158911 0.8694503719158911 0.0 muscle_contraction GO:0006936 12133 220 45 1 252 1 1 false 0.8730158730158051 0.8730158730158051 2.9388717314840356E-41 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 45 1 3842 18 3 false 0.8755004374430829 0.8755004374430829 0.0 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 45 6 4582 32 3 false 0.8760566989508328 0.8760566989508328 0.0 purine-containing_compound_catabolic_process GO:0072523 12133 959 45 5 1651 11 6 false 0.87606234907007 0.87606234907007 0.0 response_to_hormone_stimulus GO:0009725 12133 611 45 1 1784 5 2 false 0.8774692541473388 0.8774692541473388 0.0 metal_ion_binding GO:0046872 12133 2699 45 6 2758 6 1 false 0.8782133475058598 0.8782133475058598 2.6200760259069314E-123 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 45 6 1218 6 2 false 0.8783281168061138 0.8783281168061138 3.12960829510125E-54 negative_regulation_of_cell_communication GO:0010648 12133 599 45 1 4860 16 3 false 0.8785231997190367 0.8785231997190367 0.0 purine-containing_compound_biosynthetic_process GO:0072522 12133 280 45 1 4251 31 6 false 0.8799655581439709 0.8799655581439709 0.0 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 45 5 2771 27 5 false 0.8807163783762474 0.8807163783762474 0.0 nuclear_chromosome GO:0000228 12133 278 45 2 2899 37 3 false 0.8834343536005611 0.8834343536005611 0.0 cytoskeleton_organization GO:0007010 12133 719 45 2 2031 9 1 false 0.8843343721516745 0.8843343721516745 0.0 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 45 6 1225 7 2 false 0.8849621359025622 0.8849621359025622 5.928244845001387E-155 hemopoiesis GO:0030097 12133 462 45 2 491 2 1 false 0.8852487634564072 0.8852487634564072 1.8682876304369947E-47 protein_modification_process GO:0036211 12133 2370 45 9 3518 16 2 false 0.8864888292585039 0.8864888292585039 0.0 regulation_of_cell_communication GO:0010646 12133 1796 45 5 6469 26 2 false 0.8871642985859397 0.8871642985859397 0.0 protein_kinase_binding GO:0019901 12133 341 45 1 384 1 1 false 0.8880208333333595 0.8880208333333595 5.20098898434574E-58 glucose_metabolic_process GO:0006006 12133 183 45 1 206 1 1 false 0.888349514563178 0.888349514563178 5.590923529140016E-31 zinc_ion_binding GO:0008270 12133 1314 45 5 1457 6 1 false 0.8897054845473631 0.8897054845473631 2.194714234876188E-202 organelle_envelope GO:0031967 12133 629 45 2 7756 45 3 false 0.8901424686054326 0.8901424686054326 0.0 cellular_lipid_metabolic_process GO:0044255 12133 606 45 2 7304 44 2 false 0.8905171163785094 0.8905171163785094 0.0 negative_regulation_of_signaling GO:0023057 12133 597 45 1 4884 17 3 false 0.8914237320470845 0.8914237320470845 0.0 divalent_inorganic_cation_homeostasis GO:0072507 12133 223 45 1 330 2 1 false 0.895532835958329 0.895532835958329 1.0852171628360601E-89 positive_regulation_of_transport GO:0051050 12133 413 45 1 4769 25 3 false 0.8967442740906602 0.8967442740906602 0.0 generation_of_precursor_metabolites_and_energy GO:0006091 12133 364 45 1 7256 44 1 false 0.8968405521474767 0.8968405521474767 0.0 regulation_of_protein_kinase_activity GO:0045859 12133 621 45 1 1169 3 3 false 0.8972853672880982 0.8972853672880982 0.0 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 45 6 1072 6 2 false 0.8980313246139551 0.8980313246139551 3.811291228230986E-41 hydrolase_activity,_acting_on_ester_bonds GO:0016788 12133 814 45 1 2556 6 1 false 0.9000619773632907 0.9000619773632907 0.0 regulation_of_signaling GO:0023051 12133 1793 45 5 6715 28 2 false 0.9035724572857736 0.9035724572857736 0.0 negative_regulation_of_cell_proliferation GO:0008285 12133 455 45 1 2949 14 3 false 0.9047970573206607 0.9047970573206607 0.0 nucleoside-triphosphatase_activity GO:0017111 12133 1059 45 5 1080 5 1 false 0.9063189430130167 0.9063189430130167 1.2343281293318376E-44 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 45 21 3611 31 3 false 0.9077264752057023 0.9077264752057023 0.0 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 45 6 3972 32 4 false 0.9092284318759385 0.9092284318759385 0.0 membrane-bounded_vesicle GO:0031988 12133 762 45 1 834 1 1 false 0.9136690647483704 0.9136690647483704 6.820230733401612E-106 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 45 4 5183 26 2 false 0.914131927789503 0.914131927789503 0.0 organophosphate_metabolic_process GO:0019637 12133 1549 45 6 7521 44 2 false 0.9145535525244137 0.9145535525244137 0.0 cell_activation GO:0001775 12133 656 45 1 7541 27 1 false 0.9147107421364558 0.9147107421364558 0.0 chromatin GO:0000785 12133 287 45 1 512 3 1 false 0.9157685334406216 0.9157685334406216 9.050120143931621E-152 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 45 5 1587 11 3 false 0.9158987102915673 0.9158987102915673 0.0 receptor_binding GO:0005102 12133 918 45 3 6397 37 1 false 0.9166577583078503 0.9166577583078503 0.0 nucleoside_phosphate_biosynthetic_process GO:1901293 12133 323 45 1 4156 31 3 false 0.9193422762131573 0.9193422762131573 0.0 developmental_process GO:0032502 12133 3447 45 11 10446 45 1 false 0.919620920305552 0.919620920305552 0.0 interphase GO:0051325 12133 233 45 1 253 1 1 false 0.9209486166006322 0.9209486166006322 4.555981744751407E-30 cellular_divalent_inorganic_cation_homeostasis GO:0072503 12133 214 45 1 297 2 2 false 0.9225816725815424 0.9225816725815424 7.435405484383431E-76 centrosome GO:0005813 12133 327 45 1 3226 24 2 false 0.9238272344365488 0.9238272344365488 0.0 ubiquitin-protein_ligase_activity GO:0004842 12133 321 45 1 558 3 2 false 0.9239386506663139 0.9239386506663139 1.7708856343357755E-164 positive_regulation_of_developmental_process GO:0051094 12133 603 45 1 4731 19 3 false 0.925415491717986 0.925415491717986 0.0 acid-amino_acid_ligase_activity GO:0016881 12133 351 45 1 379 1 1 false 0.9261213720316644 0.9261213720316644 5.324332733169013E-43 system_process GO:0003008 12133 1272 45 2 4095 12 1 false 0.9264793212773441 0.9264793212773441 0.0 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 45 1 803 2 1 false 0.9272180693969024 0.9272180693969024 1.0286714317927864E-202 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 45 5 1007 6 2 false 0.9275546322763955 0.9275546322763955 1.4040993054667365E-118 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 45 3 672 8 1 false 0.9276716105161639 0.9276716105161639 6.935915883902889E-199 nucleocytoplasmic_transport GO:0006913 12133 327 45 6 331 6 1 false 0.9291270197700552 0.9291270197700552 2.036102168267257E-9 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 45 6 7451 44 1 false 0.9295526059784944 0.9295526059784944 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 45 7 2805 7 1 false 0.929762774590391 0.929762774590391 1.0460685646312495E-69 lipid_biosynthetic_process GO:0008610 12133 360 45 1 4386 31 2 false 0.9303658572497444 0.9303658572497444 0.0 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 45 5 1006 6 2 false 0.9307446549706176 0.9307446549706176 2.1893990019353197E-116 cell_cycle_checkpoint GO:0000075 12133 202 45 1 217 1 1 false 0.9308755760368301 0.9308755760368301 1.925703524045096E-23 oxidation-reduction_process GO:0055114 12133 740 45 1 2877 9 1 false 0.9314676254290971 0.9314676254290971 0.0 cell_adhesion GO:0007155 12133 712 45 1 7542 27 2 false 0.9315914262368172 0.9315914262368172 0.0 nucleoside_catabolic_process GO:0009164 12133 952 45 5 1516 11 5 false 0.9317717030835099 0.9317717030835099 0.0 membrane_organization GO:0061024 12133 787 45 2 3745 19 1 false 0.9320138165593868 0.9320138165593868 0.0 protein_metabolic_process GO:0019538 12133 3431 45 16 7395 44 2 false 0.9329365569180386 0.9329365569180386 0.0 cell_migration GO:0016477 12133 734 45 1 785 1 1 false 0.9350318471340443 0.9350318471340443 1.8763224028220524E-81 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 45 5 1002 6 3 false 0.9351478172895329 0.9351478172895329 5.68242981185093E-113 ribonucleoside_metabolic_process GO:0009119 12133 1071 45 6 1083 6 1 false 0.9351869937110345 0.9351869937110345 1.9559437642804265E-28 calcium_ion_homeostasis GO:0055074 12133 213 45 1 286 2 2 false 0.9355171144644476 0.9355171144644476 5.1764989660558217E-70 cellular_calcium_ion_homeostasis GO:0006874 12133 205 45 1 274 2 3 false 0.9372744044275667 0.9372744044275667 1.2663672117972438E-66 regulation_of_programmed_cell_death GO:0043067 12133 1031 45 2 1410 4 2 false 0.9382470063945383 0.9382470063945383 0.0 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 45 5 1546 18 3 false 0.9417099789626018 0.9417099789626018 0.0 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 45 6 1014 6 1 false 0.9421288967944271 0.9421288967944271 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 45 6 1014 6 1 false 0.9421288967944271 0.9421288967944271 3.301546202575714E-24 neuron_part GO:0097458 12133 612 45 1 9983 45 1 false 0.9423502219180524 0.9423502219180524 0.0 regulation_of_apoptotic_process GO:0042981 12133 1019 45 2 1381 4 2 false 0.942386315685787 0.942386315685787 0.0 response_to_decreased_oxygen_levels GO:0036293 12133 202 45 1 214 1 1 false 0.9439252336448956 0.9439252336448956 7.108512362452622E-20 kinase_binding GO:0019900 12133 384 45 1 1005 6 1 false 0.9448525058381093 0.9448525058381093 2.0091697589355545E-289 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 45 20 4544 43 3 false 0.9462945460056954 0.9462945460056954 0.0 purine-containing_compound_metabolic_process GO:0072521 12133 1232 45 6 5323 42 5 false 0.9464846958676805 0.9464846958676805 0.0 protein_complex_biogenesis GO:0070271 12133 746 45 4 1525 13 1 false 0.9465447268454039 0.9465447268454039 0.0 Fc-gamma_receptor_signaling_pathway GO:0038094 12133 72 45 1 76 1 1 false 0.9473684210526206 0.9473684210526206 7.79438414622254E-7 signaling_receptor_activity GO:0038023 12133 633 45 1 1211 4 2 false 0.9483855586534191 0.9483855586534191 0.0 hexose_metabolic_process GO:0019318 12133 206 45 1 217 1 1 false 0.9493087557602818 0.9493087557602818 1.0279992997812003E-18 transcription_cofactor_activity GO:0003712 12133 456 45 6 482 7 2 false 0.9502552012114622 0.9502552012114622 1.3948726648763881E-43 chordate_embryonic_development GO:0043009 12133 471 45 4 477 4 1 false 0.9504738609333354 0.9504738609333354 6.308586670641318E-14 regulation_of_cell_death GO:0010941 12133 1062 45 2 6437 27 2 false 0.9516305950993013 0.9516305950993013 0.0 regulation_of_cellular_localization GO:0060341 12133 603 45 1 6869 33 3 false 0.9521398975330181 0.9521398975330181 0.0 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 45 3 378 3 1 false 0.9530102651893163 0.9530102651893163 2.5686196448553377E-13 small_conjugating_protein_ligase_activity GO:0019787 12133 335 45 1 351 1 1 false 0.9544159544159461 0.9544159544159461 5.577217121688537E-28 kinase_activity GO:0016301 12133 1174 45 2 1546 4 2 false 0.9545486457447276 0.9545486457447276 0.0 purine_ribonucleotide_binding GO:0032555 12133 1641 45 4 1660 4 2 false 0.9549569007756471 0.9549569007756471 8.870449707822982E-45 endoplasmic_reticulum GO:0005783 12133 854 45 2 8213 45 2 false 0.9559145841916451 0.9559145841916451 0.0 molecular_transducer_activity GO:0060089 12133 1070 45 2 10257 45 1 false 0.956447111912985 0.956447111912985 0.0 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 45 6 5657 42 2 false 0.957125269059197 0.957125269059197 0.0 negative_regulation_of_gene_expression GO:0010629 12133 817 45 5 3906 42 3 false 0.9571598801506312 0.9571598801506312 0.0 carbohydrate_metabolic_process GO:0005975 12133 515 45 1 7453 44 2 false 0.957574081489691 0.957574081489691 0.0 biological_adhesion GO:0022610 12133 714 45 1 10446 45 1 false 0.958949834645769 0.958949834645769 0.0 response_to_hexose_stimulus GO:0009746 12133 94 45 1 98 1 1 false 0.9591836734693473 0.9591836734693473 2.7683346805893783E-7 regulation_of_molecular_function GO:0065009 12133 2079 45 5 10494 45 2 false 0.9595510280317168 0.9595510280317168 0.0 organ_development GO:0048513 12133 1929 45 4 3099 10 2 false 0.9603785757181613 0.9603785757181613 0.0 calcium_ion_transport GO:0006816 12133 228 45 1 237 1 1 false 0.962025316455779 0.962025316455779 1.7939063205832563E-16 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 45 6 1007 6 2 false 0.9646921028825098 0.9646921028825098 7.008686204750717E-16 negative_regulation_of_molecular_function GO:0044092 12133 735 45 1 10257 45 2 false 0.9650371687066691 0.9650371687066691 0.0 gated_channel_activity GO:0022836 12133 204 45 1 304 3 1 false 0.9651230807986271 0.9651230807986271 4.829178211839583E-83 organophosphate_biosynthetic_process GO:0090407 12133 477 45 1 4948 33 2 false 0.9651496527977215 0.9651496527977215 0.0 apoptotic_process GO:0006915 12133 1373 45 4 1385 4 1 false 0.9657541518448847 0.9657541518448847 1.0085392941984968E-29 striated_muscle_tissue_development GO:0014706 12133 285 45 1 295 1 1 false 0.9661016949152815 0.9661016949152815 8.482306621073292E-19 vesicle-mediated_transport GO:0016192 12133 895 45 2 2783 14 1 false 0.966917671356314 0.966917671356314 0.0 ion_homeostasis GO:0050801 12133 532 45 2 677 4 1 false 0.9674468248424752 0.9674468248424752 5.041033537922393E-152 regulation_of_cellular_catabolic_process GO:0031329 12133 494 45 1 5000 33 3 false 0.9680810886396848 0.9680810886396848 0.0 transcription,_DNA-dependent GO:0006351 12133 2643 45 22 4063 42 3 false 0.9688264894480406 0.9688264894480406 0.0 mRNA_catabolic_process GO:0006402 12133 181 45 5 592 29 2 false 0.9702076762828444 0.9702076762828444 1.4563864024176219E-157 regulation_of_transport GO:0051049 12133 942 45 2 3017 15 2 false 0.9718194959332135 0.9718194959332135 0.0 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 45 6 3847 42 4 false 0.9740701078270289 0.9740701078270289 0.0 ribosome_biogenesis GO:0042254 12133 144 45 3 243 9 1 false 0.9743632217906907 0.9743632217906907 8.984879194471426E-71 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 45 1 4947 33 2 false 0.975643973803384 0.975643973803384 0.0 integral_to_membrane GO:0016021 12133 2318 45 1 2375 1 1 false 0.9760000000014666 0.9760000000014666 3.0839384482043954E-116 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 45 6 7461 44 2 false 0.9762811393734149 0.9762811393734149 0.0 organonitrogen_compound_biosynthetic_process GO:1901566 12133 548 45 1 5099 33 2 false 0.9768217548702023 0.9768217548702023 0.0 carboxylic_acid_metabolic_process GO:0019752 12133 614 45 1 7453 44 2 false 0.9775024105975275 0.9775024105975275 0.0 immune_response-activating_signal_transduction GO:0002757 12133 299 45 1 352 2 2 false 0.9776936026935474 0.9776936026935474 2.8561568566531905E-64 response_to_glucose_stimulus GO:0009749 12133 92 45 1 94 1 1 false 0.9787234042553515 0.9787234042553515 2.2878059940517224E-4 endomembrane_system GO:0012505 12133 1211 45 2 9983 45 1 false 0.9787829242032179 0.9787829242032179 0.0 cellular_protein_complex_assembly GO:0043623 12133 284 45 1 958 11 2 false 0.9795996171288442 0.9795996171288442 4.57678794545446E-252 cellular_component_movement GO:0006928 12133 1012 45 1 7541 27 1 false 0.9797167539005474 0.9797167539005474 0.0 cytoplasmic_part GO:0044444 12133 5117 45 19 9083 45 2 false 0.9801183186508877 0.9801183186508877 0.0 response_to_other_organism GO:0051707 12133 475 45 2 1194 12 2 false 0.9801670312310111 0.9801670312310111 0.0 purine_nucleoside_binding GO:0001883 12133 1631 45 4 1639 4 1 false 0.9806007488464052 0.9806007488464052 7.876250956196666E-22 mitotic_cell_cycle GO:0000278 12133 625 45 1 1295 6 1 false 0.981027784219541 0.981027784219541 0.0 multicellular_organismal_process GO:0032501 12133 4223 45 12 10446 45 1 false 0.9813927044198252 0.9813927044198252 0.0 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 45 5 1085 5 1 false 0.9816686606152377 0.9816686606152377 1.7413918354446858E-11 DNA_duplex_unwinding GO:0032508 12133 54 45 1 55 1 1 false 0.9818181818181652 0.9818181818181652 0.018181818181817966 protein_deacetylation GO:0006476 12133 57 45 1 58 1 1 false 0.982758620689673 0.982758620689673 0.017241379310345032 cellular_ion_homeostasis GO:0006873 12133 478 45 2 575 4 2 false 0.9835953445431125 0.9835953445431125 1.064446434652655E-112 localization_of_cell GO:0051674 12133 785 45 1 3467 16 1 false 0.9837196355090332 0.9837196355090332 0.0 viral_reproduction GO:0016032 12133 633 45 10 634 10 1 false 0.9842271293377558 0.9842271293377558 0.0015772870662463625 protein_complex_subunit_organization GO:0071822 12133 989 45 8 1256 14 1 false 0.9842948833314364 0.9842948833314364 2.2763776011987297E-281 protein_kinase_activity GO:0004672 12133 1014 45 1 1347 3 3 false 0.9849936396497404 0.9849936396497404 0.0 cellular_protein_metabolic_process GO:0044267 12133 3038 45 16 5899 44 2 false 0.985281925997052 0.985281925997052 0.0 purine_ribonucleoside_binding GO:0032550 12133 1629 45 4 1635 4 2 false 0.9853883665513075 0.9853883665513075 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 45 4 1639 4 1 false 0.9854238628325719 0.9854238628325719 3.7483303336303164E-17 cytoplasmic_vesicle GO:0031410 12133 764 45 1 8540 45 3 false 0.9854298996035233 0.9854298996035233 0.0 protein_localization_to_nucleus GO:0034504 12133 233 45 1 516 7 1 false 0.9855712000745093 0.9855712000745093 1.4955266190313754E-153 organic_acid_metabolic_process GO:0006082 12133 676 45 1 7326 44 2 false 0.9860593325667337 0.9860593325667337 0.0 cytoskeletal_part GO:0044430 12133 1031 45 3 5573 40 2 false 0.9861957603224206 0.9861957603224206 0.0 GTPase_activity GO:0003924 12133 612 45 1 1061 5 2 false 0.9866017251196354 0.9866017251196354 4.702100395E-313 oxoacid_metabolic_process GO:0043436 12133 667 45 1 676 1 1 false 0.9866863905329417 0.9866863905329417 1.2985791548492531E-20 cellular_protein_modification_process GO:0006464 12133 2370 45 9 3038 16 2 false 0.9875904039797088 0.9875904039797088 0.0 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 45 1 7293 43 3 false 0.9880946422126156 0.9880946422126156 0.0 protein_localization GO:0008104 12133 1434 45 8 1642 12 1 false 0.9883786584805039 0.9883786584805039 3.426309620265761E-270 GTP_metabolic_process GO:0046039 12133 625 45 1 1193 6 3 false 0.9885129091672802 0.9885129091672802 0.0 tissue_development GO:0009888 12133 1132 45 1 3099 10 1 false 0.9894758021730015 0.9894758021730015 0.0 mitochondrion GO:0005739 12133 1138 45 2 8213 45 2 false 0.9901175127102143 0.9901175127102143 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 45 1 6358 27 2 false 0.9902022975651505 0.9902022975651505 0.0 cell_projection GO:0042995 12133 976 45 1 9983 45 1 false 0.9903466610337179 0.9903466610337179 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 45 6 1319 6 1 false 0.9909194554665322 0.9909194554665322 1.1504554077729292E-6 regulation_of_gene_expression GO:0010468 12133 2935 45 22 4361 43 2 false 0.9910510444498442 0.9910510444498442 0.0 locomotion GO:0040011 12133 1045 45 1 10446 45 1 false 0.9913802946468543 0.9913802946468543 0.0 response_to_stimulus GO:0050896 12133 5200 45 15 10446 45 1 false 0.991401092915936 0.991401092915936 0.0 single-organism_metabolic_process GO:0044710 12133 2877 45 9 8027 44 1 false 0.9914799503053688 0.9914799503053688 0.0 Golgi_apparatus GO:0005794 12133 828 45 1 8213 45 2 false 0.991733940661577 0.991733940661577 0.0 single-organism_process GO:0044699 12133 8052 45 28 10446 45 1 false 0.9923918470219423 0.9923918470219423 0.0 vesicle GO:0031982 12133 834 45 1 7980 45 1 false 0.9931389202590947 0.9931389202590947 0.0 response_to_nutrient_levels GO:0031667 12133 238 45 1 260 2 1 false 0.9931392931394337 0.9931392931394337 2.081158575166241E-32 extracellular_region GO:0005576 12133 1152 45 1 10701 45 1 false 0.9941231130926833 0.9941231130926833 0.0 GTP_catabolic_process GO:0006184 12133 614 45 1 957 5 4 false 0.994195848452219 0.994195848452219 2.3934835856107606E-270 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 45 1 956 5 2 false 0.9944996427718976 0.9944996427718976 3.936677708897206E-269 cell_development GO:0048468 12133 1255 45 1 3306 11 4 false 0.9948136999220352 0.9948136999220352 0.0 ncRNA_processing GO:0034470 12133 186 45 3 649 28 2 false 0.9950130799603997 0.9950130799603997 4.048832162241149E-168 pyrophosphatase_activity GO:0016462 12133 1080 45 5 1081 5 1 false 0.995374653099011 0.995374653099011 9.250693802031629E-4 single-organism_cellular_process GO:0044763 12133 7541 45 27 9888 45 2 false 0.9953933462402935 0.9953933462402935 0.0 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 45 1 1304 3 1 false 0.9955700497870652 0.9955700497870652 1.004636319027547E-252 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 45 1 1053 6 1 false 0.9961158568153077 0.9961158568153077 1.6418245301060377E-306 regulation_of_catalytic_activity GO:0050790 12133 1692 45 2 6953 29 3 false 0.9968677143452993 0.9968677143452993 0.0 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 45 17 3120 28 4 false 0.9969345601652304 0.9969345601652304 0.0 protein_complex_assembly GO:0006461 12133 743 45 4 1214 14 3 false 0.9972043956357958 0.9972043956357958 0.0 plasma_membrane GO:0005886 12133 2594 45 4 10252 45 3 false 0.9986686360424725 0.9986686360424725 0.0 macromolecule_modification GO:0043412 12133 2461 45 9 6052 44 1 false 0.9987400638097084 0.9987400638097084 0.0 cytoskeleton GO:0005856 12133 1430 45 4 3226 24 1 false 0.9990770998667002 0.9990770998667002 0.0 single_organism_signaling GO:0044700 12133 3878 45 6 8052 28 2 false 0.9991321156316616 0.9991321156316616 0.0 anatomical_structure_morphogenesis GO:0009653 12133 1664 45 1 3447 11 2 false 0.9993012460725064 0.9993012460725064 0.0 cell_periphery GO:0071944 12133 2667 45 4 9983 45 1 false 0.9993097931704911 0.9993097931704911 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 45 18 3220 32 4 false 0.9993325402562281 0.9993325402562281 0.0 system_development GO:0048731 12133 2686 45 4 3304 10 2 false 0.9994492166906862 0.9994492166906862 0.0 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 45 6 2849 36 1 false 0.9995976118656947 0.9995976118656947 0.0 cell_communication GO:0007154 12133 3962 45 6 7541 27 1 false 0.999705536030839 0.999705536030839 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 45 7 7256 44 1 false 0.9997452610663887 0.9997452610663887 0.0 signal_transduction GO:0007165 12133 3547 45 6 6702 27 4 false 0.9997463798540251 0.9997463798540251 0.0 cytoplasm GO:0005737 12133 6938 45 24 9083 45 1 false 0.9998131027846059 0.9998131027846059 0.0 organelle_membrane GO:0031090 12133 1619 45 1 9319 45 3 false 0.999817724408247 0.999817724408247 0.0 ion_binding GO:0043167 12133 4448 45 11 8962 45 1 false 0.9998558404144596 0.9998558404144596 0.0 protein_complex GO:0043234 12133 2976 45 19 3462 31 1 false 0.9998713253287231 0.9998713253287231 0.0 nucleoside_binding GO:0001882 12133 1639 45 4 4455 36 3 false 0.9998947426116649 0.9998947426116649 0.0 signaling GO:0023052 12133 3878 45 6 10446 45 1 false 0.999909350874403 0.999909350874403 0.0 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 45 4 2560 21 2 false 0.9999492302181102 0.9999492302181102 0.0 catalytic_activity GO:0003824 12133 4901 45 9 10478 45 2 false 0.9999543510145914 0.9999543510145914 0.0 membrane GO:0016020 12133 4398 45 6 10701 45 1 false 0.9999893929490371 0.9999893929490371 0.0 membrane_part GO:0044425 12133 2995 45 1 10701 45 2 false 0.9999996305919192 0.9999996305919192 0.0 DNA_binding GO:0003677 12133 2091 45 12 2849 36 1 false 0.9999999196216339 0.9999999196216339 0.0 purine_nucleotide_binding GO:0017076 12133 1650 45 4 1997 21 1 false 0.9999999999910657 0.9999999999910657 0.0 ribonucleotide_binding GO:0032553 12133 1651 45 4 1997 21 1 false 0.9999999999924688 0.9999999999924688 0.0 GO:0000000 12133 11221 45 45 0 0 0 true 1.0 1.0 1.0 DNA-directed_RNA_polymerase_complex GO:0000428 12133 136 45 1 136 1 1 true 1.0 1.0 1.0 endonucleolytic_cleavage_involved_in_rRNA_processing GO:0000478 12133 4 45 1 4 1 2 true 1.0 1.0 1.0 endonucleolytic_cleavage_of_tricistronic_rRNA_transcript_(SSU-rRNA,_5.8S_rRNA,_LSU-rRNA) GO:0000479 12133 4 45 1 4 1 1 true 1.0 1.0 1.0 telomerase_activity GO:0003720 12133 21 45 2 21 2 1 true 1.0 1.0 1.0 blood_circulation GO:0008015 12133 307 45 2 307 2 1 true 1.0 1.0 1.0 channel_activity GO:0015267 12133 304 45 3 304 3 1 true 1.0 1.0 1.0 Sin3_complex GO:0016580 12133 12 45 1 12 1 1 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 45 2 147 2 1 true 1.0 1.0 1.0 glucose_homeostasis GO:0042593 12133 109 45 2 109 2 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 45 6 1169 6 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 45 5 417 5 1 true 1.0 1.0 1.0 phosphatidylinositol-mediated_signaling GO:0048015 12133 173 45 1 173 1 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 45 5 124 5 2 true 1.0 1.0 1.0 MLL1_complex GO:0071339 12133 25 45 1 25 1 1 true 1.0 1.0 1.0 RNA_phosphodiester_bond_hydrolysis,_endonucleolytic GO:0090502 12133 4 45 1 4 1 1 true 1.0 1.0 1.0