ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min translational_elongation GO:0006414 12133 121 16 10 3388 12 2 false 1.4503732684409086E-13 1.4503732684409086E-13 5.332026529203484E-226 ribosomal_subunit GO:0044391 12133 132 16 9 7199 15 4 false 8.124436008086258E-13 8.124436008086258E-13 2.5906239763169356E-285 translational_initiation GO:0006413 12133 160 16 9 7667 15 2 false 2.696192053735909E-12 2.696192053735909E-12 0.0 ribosome GO:0005840 12133 210 16 9 6755 14 3 false 4.005361631341192E-11 4.005361631341192E-11 0.0 viral_transcription GO:0019083 12133 145 16 9 2964 11 3 false 6.372549681570782E-11 6.372549681570782E-11 1.0927707330622845E-250 multi-organism_cellular_process GO:0044764 12133 634 16 11 9702 15 2 false 9.157222995247454E-11 9.157222995247454E-11 0.0 cytosolic_part GO:0044445 12133 178 16 9 5117 14 2 false 1.0526194183517689E-10 1.0526194183517689E-10 0.0 ribonucleoprotein_complex GO:0030529 12133 569 16 11 9264 16 2 false 1.4082171842048453E-10 1.4082171842048453E-10 0.0 structural_molecule_activity GO:0005198 12133 526 16 10 10257 16 1 false 7.00966985986528E-10 7.00966985986528E-10 0.0 cellular_component_disassembly GO:0022411 12133 351 16 9 7663 14 2 false 1.3112943877072638E-9 1.3112943877072638E-9 0.0 RNA_catabolic_process GO:0006401 12133 203 16 9 4368 14 3 false 1.3903419769820085E-9 1.3903419769820085E-9 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 16 11 6457 14 3 false 3.901755729665291E-9 3.901755729665291E-9 0.0 multi-organism_process GO:0051704 12133 1180 16 12 10446 16 1 false 4.834374444756724E-9 4.834374444756724E-9 0.0 cellular_process_involved_in_reproduction GO:0048610 12133 469 16 9 9699 15 2 false 5.173889684254037E-9 5.173889684254037E-9 0.0 catabolic_process GO:0009056 12133 2164 16 14 8027 14 1 false 1.0386786678083344E-8 1.0386786678083344E-8 0.0 cellular_catabolic_process GO:0044248 12133 1972 16 14 7289 14 2 false 1.0881378366032275E-8 1.0881378366032275E-8 0.0 translation GO:0006412 12133 457 16 10 5433 14 3 false 1.1872300967891883E-8 1.1872300967891883E-8 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 16 14 7502 14 2 false 1.2879983968573203E-8 1.2879983968573203E-8 0.0 macromolecule_catabolic_process GO:0009057 12133 820 16 11 6846 14 2 false 1.7699691682005307E-8 1.7699691682005307E-8 0.0 protein_targeting_to_ER GO:0045047 12133 104 16 9 721 10 3 false 1.7518235957111476E-7 1.7518235957111476E-7 1.514347826459292E-128 reproductive_process GO:0022414 12133 1275 16 11 10446 16 2 false 2.0931463297228197E-7 2.0931463297228197E-7 0.0 reproduction GO:0000003 12133 1345 16 11 10446 16 1 false 3.648380009544616E-7 3.648380009544616E-7 0.0 protein_targeting GO:0006605 12133 443 16 10 2378 11 2 false 4.2476796437256933E-7 4.2476796437256933E-7 0.0 macromolecular_complex GO:0032991 12133 3462 16 15 10701 16 1 false 4.867805398611261E-7 4.867805398611261E-7 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 16 12 5462 14 2 false 1.0857314987079156E-6 1.0857314987079156E-6 0.0 mRNA_metabolic_process GO:0016071 12133 573 16 10 3294 12 1 false 1.1179810577290831E-6 1.1179810577290831E-6 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 16 12 5528 14 2 false 1.1259964762266586E-6 1.1259964762266586E-6 0.0 translational_termination GO:0006415 12133 92 16 9 513 10 2 false 1.1710647925598236E-6 1.1710647925598236E-6 3.4634519853301643E-104 heterocycle_catabolic_process GO:0046700 12133 1243 16 12 5392 14 2 false 1.2245418048904433E-6 1.2245418048904433E-6 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 16 12 5388 14 2 false 1.3054081867549076E-6 1.3054081867549076E-6 0.0 cellular_localization GO:0051641 12133 1845 16 12 7707 14 2 false 1.910014872821988E-6 1.910014872821988E-6 0.0 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 16 12 4878 14 5 false 3.1110442597093898E-6 3.1110442597093898E-6 0.0 macromolecular_complex_disassembly GO:0032984 12133 199 16 9 1380 12 2 false 3.3994758683640937E-6 3.3994758683640937E-6 1.9082717261040364E-246 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 16 9 1239 11 2 false 3.997294788552297E-6 3.997294788552297E-6 4.427655683668096E-244 protein_complex_disassembly GO:0043241 12133 154 16 9 1031 12 2 false 4.412369324822407E-6 4.412369324822407E-6 4.7545827865276796E-188 macromolecular_complex_subunit_organization GO:0043933 12133 1256 16 12 3745 13 1 false 1.7600235453663197E-5 1.7600235453663197E-5 0.0 cytosolic_ribosome GO:0022626 12133 92 16 9 296 9 2 false 2.04346628581382E-5 2.04346628581382E-5 4.2784789004852985E-79 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 16 9 516 11 1 false 4.13049678158211E-5 4.13049678158211E-5 8.917305549619806E-119 viral_genome_expression GO:0019080 12133 153 16 9 557 10 2 false 5.7071191897673434E-5 5.7071191897673434E-5 1.6461772406083414E-141 viral_infectious_cycle GO:0019058 12133 213 16 10 557 10 1 false 5.8530777730238104E-5 5.8530777730238104E-5 3.455075709157513E-160 structural_constituent_of_ribosome GO:0003735 12133 152 16 9 526 10 1 false 8.880769527858203E-5 8.880769527858203E-5 1.18011379183299E-136 establishment_of_localization GO:0051234 12133 2833 16 12 10446 16 2 false 9.019296484654738E-5 9.019296484654738E-5 0.0 localization GO:0051179 12133 3467 16 13 10446 16 1 false 1.0899368183623642E-4 1.0899368183623642E-4 0.0 mRNA_catabolic_process GO:0006402 12133 181 16 9 592 10 2 false 1.489235242469682E-4 1.489235242469682E-4 1.4563864024176219E-157 cytosol GO:0005829 12133 2226 16 13 5117 14 1 false 1.6382896128138704E-4 1.6382896128138704E-4 0.0 protein_targeting_to_membrane GO:0006612 12133 145 16 9 443 10 1 false 2.608021229977895E-4 2.608021229977895E-4 5.648405296311656E-121 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 16 13 10446 16 1 false 3.5516605167121946E-4 3.5516605167121946E-4 0.0 protein_metabolic_process GO:0019538 12133 3431 16 13 7395 14 2 false 3.639281459255743E-4 3.639281459255743E-4 0.0 intracellular_transport GO:0046907 12133 1148 16 11 2815 12 2 false 3.802517959758819E-4 3.802517959758819E-4 0.0 single-organism_transport GO:0044765 12133 2323 16 11 8134 15 2 false 4.1495827252379524E-4 4.1495827252379524E-4 0.0 cellular_macromolecule_localization GO:0070727 12133 918 16 11 2206 12 2 false 4.66404536177025E-4 4.66404536177025E-4 0.0 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 16 9 220 9 2 false 0.0010661294527465597 0.0010661294527465597 1.3850176335002185E-65 negative_regulation_of_RNA_splicing GO:0033119 12133 15 16 2 1037 4 3 false 0.001153265829264147 0.001153265829264147 8.39457188486895E-34 cellular_protein_metabolic_process GO:0044267 12133 3038 16 13 5899 14 2 false 0.001295829972356678 0.001295829972356678 0.0 multi-organism_reproductive_process GO:0044703 12133 707 16 11 1275 11 1 false 0.0014717486347527865 0.0014717486347527865 0.0 protein_localization_to_organelle GO:0033365 12133 516 16 11 914 11 1 false 0.0017715956927696792 0.0017715956927696792 5.634955900168089E-271 RNA_binding GO:0003723 12133 763 16 7 2849 9 1 false 0.0020549546084569614 0.0020549546084569614 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 16 12 7980 15 1 false 0.002130743643851768 0.002130743643851768 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 16 12 7958 15 2 false 0.002191852368200201 0.002191852368200201 0.0 organelle_part GO:0044422 12133 5401 16 14 10701 16 2 false 0.0023309572282126743 0.0023309572282126743 0.0 intracellular_protein_transport GO:0006886 12133 658 16 10 1672 12 3 false 0.0023557832584555965 0.0023557832584555965 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 16 11 8962 12 1 false 0.002383644534798485 0.002383644534798485 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 16 14 8027 14 1 false 0.002563983738985992 0.002563983738985992 0.0 regulation_of_RNA_splicing GO:0043484 12133 52 16 2 3151 5 3 false 0.0025880037556097624 0.0025880037556097624 1.4828410310444421E-114 pore_complex GO:0046930 12133 84 16 2 5051 5 3 false 0.0026455898600971067 0.0026455898600971067 5.4712090537168384E-185 organic_cyclic_compound_binding GO:0097159 12133 4407 16 11 8962 12 1 false 0.0026653462771640112 0.0026653462771640112 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 16 14 7341 14 5 false 0.0029139073844013734 0.0029139073844013734 0.0 negative_regulation_of_ERBB_signaling_pathway GO:1901185 12133 39 16 2 705 2 3 false 0.0029859767891684606 0.0029859767891684606 4.9570646354646075E-65 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 16 2 2474 4 3 false 0.003823096982751501 0.003823096982751501 1.917782059478808E-128 regulation_of_ERBB_signaling_pathway GO:1901184 12133 61 16 2 1663 3 2 false 0.0038785645962926348 0.0038785645962926348 5.186655572840897E-113 intracellular_transport_of_viral_material GO:0075733 12133 23 16 2 355 2 2 false 0.004026418397390288 0.004026418397390288 1.1844258992565298E-36 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 16 14 7451 14 1 false 0.004255319117506023 0.004255319117506023 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 16 14 7256 14 1 false 0.004479452808094114 0.004479452808094114 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 16 14 7256 14 1 false 0.004569387687544263 0.004569387687544263 0.0 multi-organism_transport GO:0044766 12133 29 16 2 3441 13 2 false 0.005051184069897385 0.005051184069897385 2.716860412473803E-72 establishment_of_protein_localization GO:0045184 12133 1153 16 10 3010 13 2 false 0.00533852107909145 0.00533852107909145 0.0 GTP_binding GO:0005525 12133 292 16 3 1635 3 3 false 0.005648301156507907 0.005648301156507907 0.0 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 16 14 7275 14 2 false 0.006392703200658609 0.006392703200658609 0.0 regulation_of_ligase_activity GO:0051340 12133 98 16 2 2061 3 2 false 0.006508192737853441 0.006508192737853441 1.6310105681359867E-170 macromolecule_localization GO:0033036 12133 1642 16 11 3467 13 1 false 0.006660029431938832 0.006660029431938832 0.0 cellular_protein_localization GO:0034613 12133 914 16 11 1438 11 2 false 0.006690789161849351 0.006690789161849351 0.0 protein_localization_to_nuclear_pore GO:0090204 12133 1 16 1 233 2 1 false 0.00858369098712472 0.00858369098712472 0.004291845493562596 cytoplasmic_part GO:0044444 12133 5117 16 14 9083 16 2 false 0.008753849957544258 0.008753849957544258 0.0 Notch_signaling_pathway GO:0007219 12133 113 16 2 1975 3 1 false 0.009373490683346924 0.009373490683346924 2.33429872590278E-187 biosynthetic_process GO:0009058 12133 4179 16 12 8027 14 1 false 0.009734002840782147 0.009734002840782147 0.0 positive_regulation_of_ligase_activity GO:0051351 12133 84 16 2 1424 3 3 false 0.009925183586972058 0.009925183586972058 5.130084211911676E-138 gene_expression GO:0010467 12133 3708 16 13 6052 14 1 false 0.010281214648074057 0.010281214648074057 0.0 nuclear_pore GO:0005643 12133 69 16 2 2781 7 3 false 0.011756351570883436 0.011756351570883436 8.971129873692015E-140 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 16 5 201 9 3 false 0.011771421469452589 0.011771421469452589 2.854176062301069E-41 macromolecule_biosynthetic_process GO:0009059 12133 3475 16 12 6537 14 2 false 0.012014803124495512 0.012014803124495512 0.0 cytoplasm GO:0005737 12133 6938 16 16 9083 16 1 false 0.013375298008689317 0.013375298008689317 0.0 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 16 2 1097 2 3 false 0.013733540046170455 0.013733540046170455 8.208279871491876E-172 intracellular_organelle_part GO:0044446 12133 5320 16 14 9083 16 3 false 0.01381612291568843 0.01381612291568843 0.0 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 16 2 1813 3 1 false 0.013940585910630117 0.013940585910630117 4.219154160176784E-199 negative_regulation_of_ligase_activity GO:0051352 12133 71 16 2 1003 3 3 false 0.014153970399010828 0.014153970399010828 8.698138776450475E-111 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 16 14 7569 14 2 false 0.015148493180212188 0.015148493180212188 0.0 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 16 2 2180 4 2 false 0.015176948826402189 0.015176948826402189 1.341003616993524E-193 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 16 2 759 2 3 false 0.015521742606744798 0.015521742606744798 1.1458874617943115E-123 ligase_activity GO:0016874 12133 504 16 3 4901 6 1 false 0.01705050657838708 0.01705050657838708 0.0 regulation_of_protein_ubiquitination GO:0031396 12133 176 16 2 1344 2 2 false 0.017063787540350758 0.017063787540350758 8.0617715234352E-226 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 16 12 6146 14 3 false 0.017298048980765902 0.017298048980765902 0.0 regulation_of_protein_catabolic_process GO:0042176 12133 150 16 2 1912 3 3 false 0.017402643328565365 0.017402643328565365 1.3832082048306078E-227 organic_substance_biosynthetic_process GO:1901576 12133 4134 16 12 7470 14 2 false 0.01800346648754931 0.01800346648754931 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 16 12 6846 14 2 false 0.018490084383548423 0.018490084383548423 0.0 protein_transport GO:0015031 12133 1099 16 10 1627 10 2 false 0.01951202998674833 0.01951202998674833 0.0 cellular_biosynthetic_process GO:0044249 12133 4077 16 12 7290 14 2 false 0.019981402968157598 0.019981402968157598 0.0 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 16 3 2370 3 1 false 0.02008914484716724 0.02008914484716724 0.0 guanyl_nucleotide_binding GO:0019001 12133 450 16 3 1650 3 1 false 0.020187152394412516 0.020187152394412516 0.0 guanyl_ribonucleotide_binding GO:0032561 12133 450 16 3 1641 3 2 false 0.02052132914292768 0.02052132914292768 0.0 transcription_factor_binding GO:0008134 12133 715 16 3 6397 6 1 false 0.021452834272537424 0.021452834272537424 0.0 cytoplasmic_transport GO:0016482 12133 666 16 10 1148 11 1 false 0.021971909039371896 0.021971909039371896 0.0 regulation_of_binding GO:0051098 12133 172 16 2 9142 13 2 false 0.023956740438987364 0.023956740438987364 0.0 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 16 9 174 9 1 false 0.025298559612664015 0.025298559612664015 2.5039480990851377E-47 establishment_of_localization_in_cell GO:0051649 12133 1633 16 11 2978 13 2 false 0.025945378012743305 0.025945378012743305 0.0 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 16 2 1056 4 3 false 0.02789899497435438 0.02789899497435438 4.764817151311381E-118 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 16 2 3297 6 3 false 0.029428786540914725 0.029428786540914725 4.623981712175632E-272 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 16 1 1199 1 2 false 0.030025020850713485 0.030025020850713485 9.194442294553035E-70 RNA_metabolic_process GO:0016070 12133 3294 16 12 5627 14 2 false 0.031233692139722716 0.031233692139722716 0.0 intracellular_receptor_signaling_pathway GO:0030522 12133 217 16 2 3547 5 1 false 0.03294721469176112 0.03294721469176112 0.0 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 16 2 953 4 3 false 0.033897798496316967 0.033897798496316967 1.5807807987211998E-114 regulation_of_cell_cycle_arrest GO:0071156 12133 89 16 2 481 2 2 false 0.03392238392239327 0.03392238392239327 1.91357850692127E-99 positive_regulation_of_protein_binding GO:0032092 12133 37 16 1 6397 6 3 false 0.034218989776948594 0.034218989776948594 2.3062856812384995E-98 antigen_processing_and_presentation GO:0019882 12133 185 16 2 1618 3 1 false 0.03608539885798134 0.03608539885798134 5.091289488805967E-249 negative_regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042059 12133 39 16 2 197 2 3 false 0.03838185020200678 0.03838185020200678 3.777320475653026E-42 proteasome_accessory_complex GO:0022624 12133 23 16 1 9248 16 3 false 0.03908982029574336 0.03908982029574336 1.6042989552874397E-69 telomeric_DNA_binding GO:0042162 12133 16 16 1 1189 3 1 false 0.039862339873044016 0.039862339873044016 1.4512187070438412E-36 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 16 9 145 9 1 false 0.04140665375930323 0.04140665375930323 1.7288474062512548E-37 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 16 2 341 2 4 false 0.04286700017249871 0.04286700017249871 3.257446469032824E-75 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 16 2 362 2 4 false 0.048361671844634496 0.048361671844634496 1.827388630734988E-82 negative_regulation_of_DNA_binding GO:0043392 12133 35 16 1 2119 3 3 false 0.0487603613858628 0.0487603613858628 5.275494739019896E-77 negative_regulation_of_protein_modification_process GO:0031400 12133 328 16 2 2431 3 3 false 0.04959567167858437 0.04959567167858437 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 16 1 3208 4 2 false 0.050173479210917075 0.050173479210917075 7.591030632914061E-95 regulation_of_cell_cycle GO:0051726 12133 659 16 3 6583 9 2 false 0.052992394795297215 0.052992394795297215 0.0 cellular_metabolic_process GO:0044237 12133 7256 16 14 10007 15 2 false 0.05371762987471756 0.05371762987471756 0.0 organic_substance_transport GO:0071702 12133 1580 16 10 2783 12 1 false 0.05389526430686675 0.05389526430686675 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 16 14 7451 14 1 false 0.0542441885933158 0.0542441885933158 0.0 protein_complex_subunit_organization GO:0071822 12133 989 16 12 1256 12 1 false 0.05601131550008343 0.05601131550008343 2.2763776011987297E-281 cellular_protein_complex_localization GO:0034629 12133 5 16 1 930 11 2 false 0.057878887160746885 0.057878887160746885 1.7435880605018067E-13 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 16 2 389 2 3 false 0.05792012296928627 0.05792012296928627 8.074632425282073E-93 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 16 1 1977 3 3 false 0.05804959566653817 0.05804959566653817 8.49513097758148E-83 palate_development GO:0060021 12133 62 16 1 3099 3 1 false 0.05884520433084847 0.05884520433084847 2.0367343521071395E-131 organelle GO:0043226 12133 7980 16 15 10701 16 1 false 0.05891472192275929 0.05891472192275929 0.0 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 16 2 3842 4 3 false 0.06131820816817354 0.06131820816817354 0.0 virion_assembly GO:0019068 12133 11 16 1 2070 12 4 false 0.06209735314181334 0.06209735314181334 1.3710102562261885E-29 response_to_cytokine_stimulus GO:0034097 12133 461 16 2 1783 2 1 false 0.06674207646346839 0.06674207646346839 0.0 cytokine-mediated_signaling_pathway GO:0019221 12133 318 16 2 2013 3 2 false 0.06684620209545143 0.06684620209545143 0.0 regulation_of_innate_immune_response GO:0045088 12133 226 16 2 868 2 3 false 0.06756972238610445 0.06756972238610445 2.196344369914344E-215 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 16 1 243 1 2 false 0.06995884773662231 0.06995884773662231 1.7559807727942103E-26 Notch_receptor_processing GO:0007220 12133 17 16 1 3038 13 1 false 0.07048692085338076 0.07048692085338076 2.325698863690895E-45 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 16 2 278 2 3 false 0.07402020621770027 0.07402020621770027 2.8121052478162137E-70 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 16 2 1398 2 2 false 0.07413187670699904 0.07413187670699904 0.0 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 16 3 2556 3 1 false 0.0763686001761799 0.0763686001761799 0.0 cell_cycle GO:0007049 12133 1295 16 5 7541 14 1 false 0.07661757196380667 0.07661757196380667 0.0 regulation_of_cellular_amino_acid_metabolic_process GO:0006521 12133 55 16 1 4147 6 4 false 0.07702825670874143 0.07702825670874143 1.925356420452305E-126 coated_pit GO:0005905 12133 52 16 1 10213 16 3 false 0.07848211089748264 0.07848211089748264 3.070128605674566E-141 SUMO_ligase_activity GO:0019789 12133 9 16 1 335 3 1 false 0.07868007430078185 0.07868007430078185 7.610794818623194E-18 negative_regulation_of_metabolic_process GO:0009892 12133 1354 16 5 8327 15 3 false 0.08216426743597074 0.08216426743597074 0.0 regulation_of_protein_binding GO:0043393 12133 95 16 1 6398 6 2 false 0.08588029047175079 0.08588029047175079 5.5524328548337306E-214 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 16 5 7606 15 4 false 0.08671795032301062 0.08671795032301062 0.0 protein_polyubiquitination GO:0000209 12133 163 16 2 548 2 1 false 0.08809164787360622 0.08809164787360622 3.681189236491621E-144 nucleus_organization GO:0006997 12133 62 16 1 2031 3 1 false 0.08885570173255763 0.08885570173255763 6.73570952581451E-120 single-organism_process GO:0044699 12133 8052 16 15 10446 16 1 false 0.08925783265217596 0.08925783265217596 0.0 cell_cycle_process GO:0022402 12133 953 16 4 7541 14 2 false 0.08999454058110973 0.08999454058110973 0.0 cellular_response_to_stress GO:0033554 12133 1124 16 3 4743 5 2 false 0.09015485629631748 0.09015485629631748 0.0 regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042058 12133 60 16 2 198 2 2 false 0.09075526842023063 0.09075526842023063 2.9049351003528108E-52 nuclear_envelope GO:0005635 12133 258 16 2 3962 8 3 false 0.0911621307589016 0.0911621307589016 0.0 regulation_of_defense_response GO:0031347 12133 387 16 2 1253 2 2 false 0.09522322145702387 0.09522322145702387 0.0 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 16 11 5597 14 2 false 0.09550946039284838 0.09550946039284838 0.0 nuclear_body_organization GO:0030575 12133 6 16 1 62 1 1 false 0.09677419354838807 0.09677419354838807 1.626690238926508E-8 microtubule_cytoskeleton_organization GO:0000226 12133 259 16 2 831 2 2 false 0.09688138836934784 0.09688138836934784 4.0880234187670296E-223 regulation_of_response_to_cytokine_stimulus GO:0060759 12133 76 16 1 2275 3 2 false 0.09695024881975448 0.09695024881975448 4.9547358949088833E-144 heterocycle_biosynthetic_process GO:0018130 12133 3248 16 11 5588 14 2 false 0.09739617568084995 0.09739617568084995 0.0 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 16 11 5686 14 2 false 0.09855161425227396 0.09855161425227396 0.0 regulation_of_cellular_amine_metabolic_process GO:0033238 12133 69 16 1 4026 6 3 false 0.09858363769386617 0.09858363769386617 5.643300821418702E-151 negative_regulation_of_binding GO:0051100 12133 72 16 1 9054 13 3 false 0.09865040453062812 0.09865040453062812 1.0408990583833388E-181 proteasomal_protein_catabolic_process GO:0010498 12133 231 16 3 498 3 2 false 0.09910781244015684 0.09910781244015684 1.2543475178088858E-148 cellular_response_to_oxygen_levels GO:0071453 12133 85 16 1 1663 2 2 false 0.09964159417878483 0.09964159417878483 4.192529980934564E-145 positive_regulation_of_binding GO:0051099 12133 73 16 1 9050 13 3 false 0.09999705377437344 0.09999705377437344 8.738239425278628E-184 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 16 11 5629 14 2 false 0.10140214493978356 0.10140214493978356 0.0 negative_regulation_of_molecular_function GO:0044092 12133 735 16 3 10257 16 2 false 0.10211157877906593 0.10211157877906593 0.0 proteasome_complex GO:0000502 12133 62 16 1 9248 16 2 false 0.10211680674750058 0.10211680674750058 4.919625587422917E-161 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 16 2 260 2 3 false 0.10353430353430498 0.10353430353430498 1.712440969539876E-70 cytoplasmic_microtubule GO:0005881 12133 41 16 1 5210 14 2 false 0.10483508607731051 0.10483508607731051 1.5944596258703277E-103 regulation_of_cytokine-mediated_signaling_pathway GO:0001959 12133 70 16 1 1785 3 3 false 0.11315465400313536 0.11315465400313536 1.145730192869727E-127 ERBB_signaling_pathway GO:0038127 12133 199 16 2 586 2 1 false 0.1149383040168364 0.1149383040168364 2.435227003721618E-162 regulation_of_proteasomal_protein_catabolic_process GO:0061136 12133 67 16 1 1672 3 5 false 0.11552873310719307 0.11552873310719307 1.5388096674355026E-121 regulation_of_DNA_binding GO:0051101 12133 67 16 1 2162 4 2 false 0.11839354128497535 0.11839354128497535 3.7616659824415835E-129 endomembrane_system GO:0012505 12133 1211 16 4 9983 16 1 false 0.11962058487559837 0.11962058487559837 0.0 regulation_of_immune_response GO:0050776 12133 533 16 2 2461 3 3 false 0.12028374649395612 0.12028374649395612 0.0 RNA_biosynthetic_process GO:0032774 12133 2751 16 11 4191 13 3 false 0.12215944078516638 0.12215944078516638 0.0 DNA_damage_checkpoint GO:0000077 12133 126 16 2 574 3 2 false 0.12289778922392475 0.12289778922392475 1.5833464450994651E-130 nucleus GO:0005634 12133 4764 16 8 7259 9 1 false 0.12889264989135094 0.12889264989135094 0.0 response_to_DNA_damage_stimulus GO:0006974 12133 570 16 3 1124 3 1 false 0.13007580831542515 0.13007580831542515 0.0 hormone_receptor_binding GO:0051427 12133 122 16 1 918 1 1 false 0.1328976034858756 0.1328976034858756 1.5301276126382055E-155 membrane-enclosed_lumen GO:0031974 12133 3005 16 7 10701 16 1 false 0.13312521264384353 0.13312521264384353 0.0 protein_C-terminus_binding GO:0008022 12133 157 16 1 6397 6 1 false 0.1385624537097233 0.1385624537097233 2.34014E-319 regulation_of_response_to_interferon-gamma GO:0060330 12133 23 16 1 319 2 3 false 0.1392125549575066 0.1392125549575066 1.507111625705858E-35 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 16 2 2943 8 3 false 0.1394123181589053 0.1394123181589053 0.0 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 16 2 170 2 3 false 0.14034110685692527 0.14034110685692527 2.004129732487635E-48 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 16 1 1384 1 2 false 0.14089595375722647 0.14089595375722647 1.3395090025049634E-243 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 16 5 6103 14 3 false 0.14126914846183403 0.14126914846183403 0.0 GTP_metabolic_process GO:0046039 12133 625 16 3 1193 3 3 false 0.14345780882292297 0.14345780882292297 0.0 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 16 2 269 2 2 false 0.1457304555290202 0.1457304555290202 3.613555574654199E-77 small_conjugating_protein_ligase_binding GO:0044389 12133 147 16 1 1005 1 1 false 0.1462686567164614 0.1462686567164614 6.302468729220369E-181 positive_regulation_of_proteolysis GO:0045862 12133 69 16 1 1334 3 3 false 0.1473893636505883 0.1473893636505883 2.369917275782091E-117 negative_regulation_of_catalytic_activity GO:0043086 12133 588 16 2 4970 6 3 false 0.15190361330374724 0.15190361330374724 0.0 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 16 3 742 3 2 false 0.152626152129731 0.152626152129731 9.121396596563632E-222 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 16 1 1130 1 2 false 0.15309734513280862 0.15309734513280862 2.620015602340521E-209 microtubule-based_process GO:0007017 12133 378 16 2 7541 14 1 false 0.1534913535852493 0.1534913535852493 0.0 positive_regulation_of_cell_cycle GO:0045787 12133 98 16 1 3492 6 3 false 0.15710846147363922 0.15710846147363922 2.23767062140918E-193 protein_sumoylation GO:0016925 12133 32 16 1 578 3 1 false 0.15732150745917822 0.15732150745917822 2.618927943730716E-53 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 16 1 6380 8 3 false 0.15733903412904593 0.15733903412904593 2.5067679665083333E-283 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 16 1 1130 1 2 false 0.159292035398306 0.159292035398306 1.9819409219356823E-214 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 16 1 2735 6 4 false 0.15950463274758916 0.15950463274758916 2.836340851870023E-153 mitotic_cell_cycle GO:0000278 12133 625 16 4 1295 5 1 false 0.16605486347118137 0.16605486347118137 0.0 negative_regulation_of_cellular_process GO:0048523 12133 2515 16 6 9689 15 3 false 0.17007555846417177 0.17007555846417177 0.0 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 16 4 200 9 3 false 0.1704382094734657 0.1704382094734657 7.491323649368413E-49 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 16 1 1054 2 3 false 0.17049146650674626 0.17049146650674626 5.573854633657796E-137 regulation_of_response_to_stress GO:0080134 12133 674 16 2 3466 4 2 false 0.17226005584802956 0.17226005584802956 0.0 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 16 1 1679 3 3 false 0.17307564331753364 0.17307564331753364 1.5952227787322578E-167 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 16 4 5447 14 3 false 0.1741813983729164 0.1741813983729164 0.0 nuclear_lumen GO:0031981 12133 2490 16 7 3186 7 2 false 0.17777621015662515 0.17777621015662515 0.0 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 16 1 1198 3 4 false 0.17863849634194232 0.17863849634194232 2.335035261625238E-122 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 16 2 183 2 2 false 0.18032786885244478 0.18032786885244478 1.0111677973178846E-53 ribose_phosphate_metabolic_process GO:0019693 12133 1207 16 3 3007 4 3 false 0.18065952312646538 0.18065952312646538 0.0 negative_regulation_of_signal_transduction GO:0009968 12133 571 16 2 3588 5 5 false 0.18176875448970184 0.18176875448970184 0.0 embryonic_organ_development GO:0048568 12133 275 16 1 2873 2 3 false 0.1823055786894839 0.1823055786894839 0.0 cellular_response_to_hypoxia GO:0071456 12133 79 16 1 1210 3 3 false 0.18349963188627 0.18349963188627 3.484581288071841E-126 sequence-specific_DNA_binding GO:0043565 12133 1189 16 3 2091 3 1 false 0.18365817113669242 0.18365817113669242 0.0 regulation_of_cellular_ketone_metabolic_process GO:0010565 12133 133 16 1 3992 6 2 false 0.1840769898853915 0.1840769898853915 1.512735013638228E-252 cell_cycle_arrest GO:0007050 12133 202 16 2 998 4 2 false 0.18419960366416965 0.18419960366416965 1.5077994882682823E-217 protein_export_from_nucleus GO:0006611 12133 46 16 1 2428 11 3 false 0.19009648372271326 0.19009648372271326 1.6048237175829586E-98 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 16 3 381 3 2 false 0.19141479693878807 0.19141479693878807 4.820433761728018E-112 GTPase_activity GO:0003924 12133 612 16 3 1061 3 2 false 0.19151608627176514 0.19151608627176514 4.702100395E-313 regulation_of_interferon-gamma-mediated_signaling_pathway GO:0060334 12133 22 16 1 114 1 3 false 0.1929824561403555 0.1929824561403555 5.496543393824805E-24 nucleic_acid_binding GO:0003676 12133 2849 16 9 4407 11 2 false 0.19306125610476518 0.19306125610476518 0.0 cell_division GO:0051301 12133 438 16 2 7541 14 1 false 0.19367971564153896 0.19367971564153896 0.0 type_I_interferon_production GO:0032606 12133 71 16 1 362 1 1 false 0.19613259668509953 0.19613259668509953 2.8677775679244762E-77 mRNA_binding GO:0003729 12133 91 16 2 763 7 1 false 0.1987744195292825 0.1987744195292825 1.7788235024198917E-120 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 16 1 859 1 3 false 0.20023282887085594 0.20023282887085594 4.662302019201105E-186 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 16 11 4989 14 5 false 0.20086326757511447 0.20086326757511447 0.0 protein_complex_localization GO:0031503 12133 29 16 1 1434 11 1 false 0.20190721230802738 0.20190721230802738 3.39152835029198E-61 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 16 1 201 1 3 false 0.20398009950248341 0.20398009950248341 9.949481941404742E-44 response_to_interferon-gamma GO:0034341 12133 97 16 1 900 2 2 false 0.20404647138796903 0.20404647138796903 5.665951698458868E-133 angiogenesis GO:0001525 12133 300 16 1 2776 2 3 false 0.2044941194790333 0.2044941194790333 0.0 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 16 4 5032 14 4 false 0.20511210933372215 0.20511210933372215 0.0 regulation_of_type_I_interferon_production GO:0032479 12133 67 16 1 325 1 2 false 0.2061538461538324 0.2061538461538324 2.788484219003069E-71 regulation_of_cytokine_production GO:0001817 12133 323 16 1 1562 1 2 false 0.20678617157496743 0.20678617157496743 0.0 positive_regulation_of_protein_modification_process GO:0031401 12133 708 16 2 2417 3 3 false 0.20703984434167866 0.20703984434167866 0.0 negative_regulation_of_signaling GO:0023057 12133 597 16 2 4884 7 3 false 0.20711602456452002 0.20711602456452002 0.0 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 16 1 859 1 3 false 0.2083818393481664 0.2083818393481664 3.480270935062193E-190 negative_regulation_of_cell_cycle GO:0045786 12133 298 16 2 3131 9 3 false 0.2085163921703977 0.2085163921703977 0.0 negative_regulation_of_cell_communication GO:0010648 12133 599 16 2 4860 7 3 false 0.20983618323328374 0.20983618323328374 0.0 mitotic_spindle_organization GO:0007052 12133 37 16 1 648 4 2 false 0.21001217530366648 0.21001217530366648 3.6765869552528886E-61 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I GO:0042590 12133 73 16 2 158 2 2 false 0.21188422155928965 0.21188422155928965 6.794891168245598E-47 negative_regulation_of_cytokine_production GO:0001818 12133 114 16 1 529 1 3 false 0.21550094517957671 0.21550094517957671 4.407958658606205E-119 negative_regulation_of_type_I_interferon_production GO:0032480 12133 32 16 1 148 1 3 false 0.21621621621620796 0.21621621621620796 3.492638478654734E-33 regulation_of_protein_complex_assembly GO:0043254 12133 185 16 1 1610 2 3 false 0.2166732934695749 0.2166732934695749 1.34790682725651E-248 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 16 2 7293 9 3 false 0.21696083177789055 0.21696083177789055 0.0 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 16 1 695 2 3 false 0.21711276511940794 0.21711276511940794 3.5521820546065696E-107 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 16 3 1053 3 1 false 0.21785283660815685 0.21785283660815685 1.6418245301060377E-306 response_to_hypoxia GO:0001666 12133 200 16 1 2540 3 2 false 0.21818760633982018 0.21818760633982018 2.6634431659671552E-303 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 16 2 134 2 2 false 0.21916732128828628 0.21916732128828628 8.460684206886756E-40 intracellular_part GO:0044424 12133 9083 16 16 9983 16 2 false 0.220279486847162 0.220279486847162 0.0 negative_regulation_of_biological_process GO:0048519 12133 2732 16 6 10446 16 2 false 0.22112290788143812 0.22112290788143812 0.0 regulation_of_proteolysis GO:0030162 12133 146 16 1 1822 3 2 false 0.22175816505026014 0.22175816505026014 4.197674460173735E-220 cell_cycle_phase_transition GO:0044770 12133 415 16 3 953 4 1 false 0.22196399820082402 0.22196399820082402 1.4433288987581492E-282 protein_localization GO:0008104 12133 1434 16 11 1642 11 1 false 0.22429327869849947 0.22429327869849947 3.426309620265761E-270 cellular_protein_catabolic_process GO:0044257 12133 409 16 3 3174 13 3 false 0.2293819690985121 0.2293819690985121 0.0 pigment_granule GO:0048770 12133 87 16 1 712 2 1 false 0.2296022377093135 0.2296022377093135 3.4546414966613156E-114 single-organism_cellular_process GO:0044763 12133 7541 16 14 9888 16 2 false 0.23030961991368992 0.23030961991368992 0.0 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 16 4 3631 12 4 false 0.23045490079380554 0.23045490079380554 0.0 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 16 1 1663 3 2 false 0.2305035481221394 0.2305035481221394 7.181952736648417E-207 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 16 1 835 1 2 false 0.23233532934123596 0.23233532934123596 8.0742416973675315E-196 molecular_function GO:0003674 12133 10257 16 16 11221 16 1 false 0.23734700866415234 0.23734700866415234 0.0 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 16 1 522 1 3 false 0.23754789272030183 0.23754789272030183 1.2617392241842968E-123 rRNA_binding GO:0019843 12133 29 16 1 763 7 1 false 0.23840226996325964 0.23840226996325964 3.8668021308986908E-53 regulation_of_immune_system_process GO:0002682 12133 794 16 2 6789 8 2 false 0.23851214241535112 0.23851214241535112 0.0 nuclear_membrane GO:0031965 12133 157 16 1 4084 7 3 false 0.2401343758452186 0.2401343758452186 2.8056123615014062E-288 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 16 2 130 2 2 false 0.2404293381037601 0.2404293381037601 1.0680656075518395E-38 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 16 2 5830 8 3 false 0.24125676291788292 0.24125676291788292 0.0 cytokine_production GO:0001816 12133 362 16 1 4095 3 1 false 0.24250218409668184 0.24250218409668184 0.0 innate_immune_response GO:0045087 12133 626 16 2 1268 2 2 false 0.24353337200828554 0.24353337200828554 0.0 blood_vessel_morphogenesis GO:0048514 12133 368 16 1 2812 2 3 false 0.24464952510765503 0.24464952510765503 0.0 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 16 2 2877 3 6 false 0.24629875320615813 0.24629875320615813 0.0 metabolic_process GO:0008152 12133 8027 16 14 10446 16 1 false 0.24689746244143335 0.24689746244143335 0.0 cellular_ketone_metabolic_process GO:0042180 12133 155 16 1 7667 14 3 false 0.24886994771563875 0.24886994771563875 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 16 1 2025 3 2 false 0.2535744732677491 0.2535744732677491 5.184659787643375E-271 viral_assembly,_maturation,_egress,_and_release GO:0019067 12133 16 16 1 557 10 2 false 0.25463175481857686 0.25463175481857686 3.0295698614548545E-31 intracellular GO:0005622 12133 9171 16 16 9983 16 1 false 0.2570557022967573 0.2570557022967573 0.0 primary_metabolic_process GO:0044238 12133 7288 16 14 8027 14 1 false 0.2583875511248899 0.2583875511248899 0.0 positive_regulation_of_defense_response GO:0031349 12133 229 16 1 1621 2 3 false 0.26265908104270097 0.26265908104270097 6.85443065618377E-286 cytoskeleton-dependent_intracellular_transport GO:0030705 12133 67 16 1 2454 11 2 false 0.2629745831939735 0.2629745831939735 6.842684271212845E-133 nucleoplasm GO:0005654 12133 1443 16 5 2767 7 2 false 0.2630539475801842 0.2630539475801842 0.0 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 16 1 650 1 2 false 0.26307692307691666 0.26307692307691666 6.010278185218431E-162 GTP_catabolic_process GO:0006184 12133 614 16 3 957 3 4 false 0.26363742804817175 0.26363742804817175 2.3934835856107606E-270 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 16 3 956 3 2 false 0.2683683854557507 0.2683683854557507 3.936677708897206E-269 protein_catabolic_process GO:0030163 12133 498 16 3 3569 13 2 false 0.2684915829743251 0.2684915829743251 0.0 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 16 3 2807 4 3 false 0.26860861972518557 0.26860861972518557 0.0 protein_maturation GO:0051604 12133 123 16 1 5551 14 2 false 0.26953574887943893 0.26953574887943893 1.3126924681575497E-255 amine_metabolic_process GO:0009308 12133 139 16 1 1841 4 1 false 0.26968987487167834 0.26968987487167834 2.897401461446105E-213 envelope GO:0031975 12133 641 16 2 9983 16 1 false 0.27449679548351863 0.27449679548351863 0.0 endocytic_vesicle_membrane GO:0030666 12133 97 16 1 352 1 2 false 0.27556818181817483 0.27556818181817483 2.1109282121886535E-89 'de_novo'_protein_folding GO:0006458 12133 51 16 1 183 1 1 false 0.27868852459015203 0.27868852459015203 1.4322240237766098E-46 viral_reproductive_process GO:0022415 12133 557 16 10 783 12 2 false 0.27907692781384086 0.27907692781384086 1.4346997744229993E-203 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 16 2 506 3 3 false 0.2810733247237542 0.2810733247237542 1.5079927652081954E-141 endosome_membrane GO:0010008 12133 248 16 1 1627 2 2 false 0.2817007887352579 0.2817007887352579 8.244139595488818E-301 PML_body GO:0016605 12133 77 16 1 272 1 1 false 0.28308823529409977 0.28308823529409977 7.662735942565743E-70 positive_regulation_of_cytokine_production GO:0001819 12133 175 16 1 614 1 3 false 0.2850162866449984 0.2850162866449984 1.2195240299259301E-158 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 16 1 856 1 3 false 0.285046728972063 0.285046728972063 2.175375701359491E-221 cytoskeleton_organization GO:0007010 12133 719 16 2 2031 3 1 false 0.28714309609081 0.28714309609081 0.0 cell_cycle_phase GO:0022403 12133 253 16 2 953 4 1 false 0.2879036989487487 0.2879036989487487 1.0384727319913012E-238 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_I GO:0002474 12133 88 16 2 163 2 1 false 0.2899341058849978 0.2899341058849978 2.2957799692832176E-48 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 16 2 415 3 3 false 0.29035582270131366 0.29035582270131366 9.462933237946419E-117 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 16 1 195 1 4 false 0.2923076923077087 0.2923076923077087 1.081664723883568E-50 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 16 2 116 2 3 false 0.2928035982009022 0.2928035982009022 2.4978330889301296E-34 vasculature_development GO:0001944 12133 441 16 1 2686 2 2 false 0.3014638285821443 0.3014638285821443 0.0 small_molecule_binding GO:0036094 12133 2102 16 4 8962 12 1 false 0.3038943633635659 0.3038943633635659 0.0 viral_protein_processing GO:0019082 12133 10 16 1 256 9 2 false 0.30542984642063725 0.30542984642063725 3.5864633505920636E-18 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 16 2 220 3 1 false 0.3060084316839271 0.3060084316839271 2.4407604211478482E-62 G1_DNA_damage_checkpoint GO:0044783 12133 70 16 2 126 2 1 false 0.30666666666666786 0.30666666666666786 3.590272155218709E-37 microtubule GO:0005874 12133 288 16 1 3267 4 3 false 0.30879271368138517 0.30879271368138517 0.0 DNA_metabolic_process GO:0006259 12133 791 16 3 5627 14 2 false 0.3133953818917045 0.3133953818917045 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 16 1 86 1 2 false 0.3139534883720948 0.3139534883720948 6.233113581740502E-23 immune_response GO:0006955 12133 1006 16 2 5335 6 2 false 0.3165463545301691 0.3165463545301691 0.0 response_to_oxygen_levels GO:0070482 12133 214 16 1 676 1 1 false 0.3165680473373286 0.3165680473373286 1.6255941364061853E-182 cellular_amine_metabolic_process GO:0044106 12133 136 16 1 5073 14 2 false 0.31677976806296454 0.31677976806296454 2.7563154132003715E-271 receptor_signaling_protein_activity GO:0005057 12133 339 16 1 1070 1 1 false 0.3168224299066703 0.3168224299066703 2.5248591221043436E-289 biological_process GO:0008150 12133 10446 16 16 11221 16 1 false 0.31794385829428184 0.31794385829428184 0.0 positive_regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032436 12133 35 16 1 288 3 4 false 0.32305347091929176 0.32305347091929176 7.428075320192054E-46 glycosyl_compound_metabolic_process GO:1901657 12133 1093 16 3 7599 14 2 false 0.3267518967103608 0.3267518967103608 0.0 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 16 1 254 1 3 false 0.3267716535432695 0.3267716535432695 3.7262148804586973E-69 cell_part GO:0044464 12133 9983 16 16 10701 16 2 false 0.3288794146437776 0.3288794146437776 0.0 cell GO:0005623 12133 9984 16 16 10701 16 1 false 0.3294073109752939 0.3294073109752939 0.0 apoptotic_signaling_pathway GO:0097190 12133 305 16 1 3954 5 2 false 0.33074116550621885 0.33074116550621885 0.0 neurotrophin_signaling_pathway GO:0038179 12133 253 16 1 2018 3 2 false 0.33107409492035167 0.33107409492035167 0.0 anion_binding GO:0043168 12133 2280 16 3 4448 4 1 false 0.3315386891459293 0.3315386891459293 0.0 positive_regulation_of_proteasomal_protein_catabolic_process GO:1901800 12133 36 16 1 287 3 4 false 0.3320863988386028 0.3320863988386028 1.2079535246838254E-46 positive_regulation_of_molecular_function GO:0044093 12133 1303 16 3 10257 16 2 false 0.3323254332573955 0.3323254332573955 0.0 signal_transduction_by_phosphorylation GO:0023014 12133 307 16 1 3947 5 2 false 0.33307282872481786 0.33307282872481786 0.0 regulation_of_protein_modification_process GO:0031399 12133 1001 16 2 2566 3 2 false 0.3377454429237858 0.3377454429237858 0.0 nuclear_body GO:0016604 12133 272 16 1 805 1 1 false 0.3378881987577754 0.3378881987577754 8.12188174084084E-223 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 16 1 1631 3 2 false 0.3388467029635467 0.3388467029635467 3.3133814045702313E-271 cell_cortex GO:0005938 12133 175 16 1 6402 15 2 false 0.34045041211956234 0.34045041211956234 0.0 chromatin_binding GO:0003682 12133 309 16 1 8962 12 1 false 0.34381415572686136 0.34381415572686136 0.0 RNA_processing GO:0006396 12133 601 16 3 3762 13 2 false 0.3452959209822677 0.3452959209822677 0.0 organelle_envelope GO:0031967 12133 629 16 2 7756 15 3 false 0.3465573040431726 0.3465573040431726 0.0 nucleoside_metabolic_process GO:0009116 12133 1083 16 3 2072 4 4 false 0.34710945740457555 0.34710945740457555 0.0 blood_vessel_development GO:0001568 12133 420 16 1 3152 3 3 false 0.3489417051828666 0.3489417051828666 0.0 multi-multicellular_organism_process GO:0044706 12133 155 16 1 4752 13 2 false 0.35056731083975595 0.35056731083975595 7.365305875596643E-296 regulation_of_signal_transduction GO:0009966 12133 1603 16 3 3826 5 4 false 0.35064223173730796 0.35064223173730796 0.0 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 16 2 5051 6 3 false 0.3508707849177015 0.3508707849177015 0.0 organic_substance_metabolic_process GO:0071704 12133 7451 16 14 8027 14 1 false 0.35227121064593847 0.35227121064593847 0.0 positive_regulation_of_transferase_activity GO:0051347 12133 445 16 1 2275 2 3 false 0.35301690394042073 0.35301690394042073 0.0 defense_response GO:0006952 12133 1018 16 2 2540 3 1 false 0.3530778942710485 0.3530778942710485 0.0 polysome GO:0005844 12133 22 16 1 569 11 1 false 0.3544709545085236 0.3544709545085236 4.138788255326549E-40 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 16 1 5033 7 3 false 0.3555439648963891 0.3555439648963891 0.0 interferon-gamma-mediated_signaling_pathway GO:0060333 12133 66 16 1 330 2 2 false 0.36048632218842164 0.36048632218842164 3.5052495329479947E-71 immune_response-regulating_signaling_pathway GO:0002764 12133 310 16 1 3626 5 2 false 0.36052798549030074 0.36052798549030074 0.0 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 16 2 1975 3 1 false 0.3614353520127967 0.3614353520127967 0.0 basal_transcription_machinery_binding GO:0001098 12133 464 16 1 6397 6 1 false 0.36363205383787794 0.36363205383787794 0.0 regulation_of_signaling GO:0023051 12133 1793 16 3 6715 8 2 false 0.3642278726149653 0.3642278726149653 0.0 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 16 1 217 2 1 false 0.36516470387434313 0.36516470387434313 4.514459380304185E-47 positive_regulation_of_cellular_catabolic_process GO:0031331 12133 106 16 1 3311 14 4 false 0.36646869606158644 0.36646869606158644 4.802217577498734E-203 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 16 3 673 4 2 false 0.36852591405447754 0.36852591405447754 4.9348138289436974E-201 positive_regulation_of_kinase_activity GO:0033674 12133 438 16 1 1181 1 3 false 0.37087214225224796 0.37087214225224796 0.0 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 16 2 217 2 2 false 0.37455197132611834 0.37455197132611834 2.2668758893633536E-62 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 16 1 1112 1 4 false 0.37500000000008227 0.37500000000008227 1.302733E-318 positive_regulation_of_phosphorylation GO:0042327 12133 563 16 1 1487 1 3 false 0.37861466039011715 0.37861466039011715 0.0 cellular_response_to_interferon-gamma GO:0071346 12133 83 16 1 392 2 2 false 0.37906466934595223 0.37906466934595223 2.629901965674187E-87 endocytic_vesicle GO:0030139 12133 152 16 1 712 2 1 false 0.3816273961348403 0.3816273961348403 1.2528026489004738E-159 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 16 1 207 1 2 false 0.38164251207729816 0.38164251207729816 2.976076769798144E-59 positive_regulation_of_metabolic_process GO:0009893 12133 1872 16 4 8366 14 3 false 0.38530516257675457 0.38530516257675457 0.0 small_ribosomal_subunit GO:0015935 12133 60 16 5 132 9 1 false 0.38590715531712744 0.38590715531712744 4.556510204279982E-39 nuclear_part GO:0044428 12133 2767 16 7 6936 15 2 false 0.3867908546269531 0.3867908546269531 0.0 intracellular_organelle GO:0043229 12133 7958 16 15 9096 16 2 false 0.3872033889669052 0.3872033889669052 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 16 1 6813 10 2 false 0.38777537118884076 0.38777537118884076 0.0 regulation_of_cell_death GO:0010941 12133 1062 16 2 6437 8 2 false 0.39009506843636993 0.39009506843636993 0.0 ribonucleotide_catabolic_process GO:0009261 12133 946 16 3 1294 3 3 false 0.39039084482127334 0.39039084482127334 0.0 regulation_of_cell_communication GO:0010646 12133 1796 16 3 6469 8 2 false 0.3912266149533059 0.3912266149533059 0.0 regulation_of_molecular_function GO:0065009 12133 2079 16 4 10494 16 2 false 0.39430930341922377 0.39430930341922377 0.0 nucleotide_catabolic_process GO:0009166 12133 969 16 3 1318 3 2 false 0.39707133310484327 0.39707133310484327 0.0 vesicle_membrane GO:0012506 12133 312 16 1 9991 16 4 false 0.3983053173379169 0.3983053173379169 0.0 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 16 2 2771 5 5 false 0.3985866823157158 0.3985866823157158 0.0 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 16 1 750 1 3 false 0.39866666666682765 0.39866666666682765 3.090255244762607E-218 regulation_of_response_to_stimulus GO:0048583 12133 2074 16 3 7292 8 2 false 0.40854139649643495 0.40854139649643495 0.0 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 16 2 2528 3 3 false 0.4102096735879659 0.4102096735879659 0.0 stress-activated_MAPK_cascade GO:0051403 12133 207 16 1 504 1 2 false 0.41071428571427093 0.41071428571427093 1.7060805667457382E-147 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 16 1 912 1 2 false 0.4111842105262834 0.4111842105262834 2.059888800891414E-267 DNA_integrity_checkpoint GO:0031570 12133 130 16 2 202 2 1 false 0.41303384069746746 0.41303384069746746 1.23666756413938E-56 rRNA_metabolic_process GO:0016072 12133 107 16 1 258 1 1 false 0.4147286821705359 0.4147286821705359 1.860360860420455E-75 establishment_of_RNA_localization GO:0051236 12133 124 16 1 2839 12 2 false 0.41549140951050073 0.41549140951050073 1.4765023034812589E-220 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 16 2 541 3 2 false 0.41838125492735057 0.41838125492735057 1.01164377942614E-160 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 16 4 7638 14 4 false 0.42125412948393925 0.42125412948393925 0.0 endosomal_part GO:0044440 12133 257 16 1 7185 15 3 false 0.4212635454476998 0.4212635454476998 0.0 positive_regulation_of_innate_immune_response GO:0045089 12133 178 16 1 740 2 4 false 0.4234685294228068 0.4234685294228068 1.4450011889246649E-176 regulation_of_catabolic_process GO:0009894 12133 554 16 2 5455 14 2 false 0.42350946880361606 0.42350946880361606 0.0 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 16 3 504 3 1 false 0.42439486586449415 0.42439486586449415 6.011520399617331E-122 cytoplasmic_vesicle GO:0031410 12133 764 16 2 8540 16 3 false 0.4259361096158441 0.4259361096158441 0.0 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 16 1 1079 1 3 false 0.42724745134375464 0.42724745134375464 5.98264E-319 positive_regulation_of_catabolic_process GO:0009896 12133 137 16 1 3517 14 3 false 0.4272514643650127 0.4272514643650127 1.0965595914697655E-250 activation_of_innate_immune_response GO:0002218 12133 155 16 1 362 1 2 false 0.4281767955801526 0.4281767955801526 1.0665156090103768E-106 cardiovascular_system_development GO:0072358 12133 655 16 1 2686 2 2 false 0.42831649313253306 0.42831649313253306 0.0 circulatory_system_development GO:0072359 12133 655 16 1 2686 2 1 false 0.42831649313253306 0.42831649313253306 0.0 signal_transduction GO:0007165 12133 3547 16 5 6702 8 4 false 0.4288470782203261 0.4288470782203261 0.0 synapse GO:0045202 12133 368 16 1 10701 16 1 false 0.42896933719208824 0.42896933719208824 0.0 positive_regulation_of_immune_response GO:0050778 12133 394 16 1 1600 2 4 false 0.4319770168855518 0.4319770168855518 0.0 regulation_of_transferase_activity GO:0051338 12133 667 16 1 2708 2 2 false 0.43201579798176304 0.43201579798176304 0.0 organelle_fission GO:0048285 12133 351 16 1 2031 3 1 false 0.4341987194944721 0.4341987194944721 0.0 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 16 3 2560 4 2 false 0.43570684744696236 0.43570684744696236 0.0 cellular_membrane_organization GO:0016044 12133 784 16 2 7541 14 2 false 0.4357299450373537 0.4357299450373537 0.0 RNA_export_from_nucleus GO:0006405 12133 72 16 1 165 1 2 false 0.43636363636365744 0.43636363636365744 1.3059643179360761E-48 rRNA_processing GO:0006364 12133 102 16 1 231 1 3 false 0.4415584415584419 0.4415584415584419 2.6685808966337758E-68 spindle_organization GO:0007051 12133 78 16 1 1776 13 3 false 0.443389992316437 0.443389992316437 2.2015050227101385E-138 positive_regulation_of_cellular_process GO:0048522 12133 2811 16 5 9694 15 3 false 0.449945382405566 0.449945382405566 0.0 response_to_biotic_stimulus GO:0009607 12133 494 16 1 5200 6 1 false 0.45076289284065746 0.45076289284065746 0.0 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 16 1 599 2 2 false 0.4533643028234985 0.4533643028234985 1.7219296535416308E-148 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 16 3 1319 3 1 false 0.454027263365971 0.454027263365971 6.536050345296563E-309 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 16 2 630 4 2 false 0.45541605160626936 0.45541605160626936 4.4826406352842784E-178 endosomal_transport GO:0016197 12133 133 16 1 2454 11 2 false 0.45893804340488736 0.45893804340488736 7.966947585336105E-224 endocytosis GO:0006897 12133 411 16 1 895 1 2 false 0.4592178770950004 0.4592178770950004 2.7872223899360555E-267 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 16 2 3605 13 4 false 0.4604519871736347 0.4604519871736347 0.0 immune_system_process GO:0002376 12133 1618 16 3 10446 16 1 false 0.4609312381283719 0.4609312381283719 0.0 cellular_response_to_organic_substance GO:0071310 12133 1347 16 2 1979 2 2 false 0.46317016233592123 0.46317016233592123 0.0 regulation_of_phosphorylation GO:0042325 12133 845 16 1 1820 1 2 false 0.4642857142855993 0.4642857142855993 0.0 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 16 4 7461 14 2 false 0.46723485870631964 0.46723485870631964 0.0 cellular_component GO:0005575 12133 10701 16 16 11221 16 1 false 0.4677986062731964 0.4677986062731964 0.0 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 16 1 5157 7 3 false 0.47088202591666767 0.47088202591666767 0.0 vesicle GO:0031982 12133 834 16 2 7980 15 1 false 0.4749406414562414 0.4749406414562414 0.0 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 16 2 929 5 2 false 0.47710157490216076 0.47710157490216076 1.7613668775256747E-246 purine_nucleotide_catabolic_process GO:0006195 12133 956 16 3 1223 3 3 false 0.4773053603106511 0.4773053603106511 6.80299167777575E-278 cellular_amino_acid_metabolic_process GO:0006520 12133 337 16 1 7342 14 3 false 0.48232958388166036 0.48232958388166036 0.0 response_to_virus GO:0009615 12133 230 16 1 475 1 1 false 0.4842105263158639 0.4842105263158639 3.548520767075247E-142 DNA_repair GO:0006281 12133 368 16 2 977 4 2 false 0.48424059968543565 0.48424059968543565 3.284245924949814E-280 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 16 2 3910 13 3 false 0.48431095318430734 0.48431095318430734 0.0 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 16 1 2035 4 3 false 0.4863689173598354 0.4863689173598354 0.0 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 16 2 442 3 3 false 0.48639595698429194 0.48639595698429194 2.4953498472018727E-132 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 16 3 1202 3 3 false 0.48715393855096295 0.48715393855096295 1.616697592155103E-269 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 16 1 129 1 1 false 0.4883720930232628 0.4883720930232628 2.169508265339551E-38 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 16 1 305 1 2 false 0.4885245901639539 0.4885245901639539 3.640759676212702E-91 regulation_of_kinase_activity GO:0043549 12133 654 16 1 1335 1 3 false 0.4898876404494377 0.4898876404494377 0.0 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 16 1 3447 3 2 false 0.4901143446364583 0.4901143446364583 0.0 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 16 1 417 1 4 false 0.4916067146282839 0.4916067146282839 8.022991700655629E-125 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 16 1 803 2 1 false 0.494616509784253 0.494616509784253 7.141936114023743E-209 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 16 1 129 1 1 false 0.4961240310077624 0.4961240310077624 2.1037655906323275E-38 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 16 1 639 1 3 false 0.49765258215962105 0.49765258215962105 1.399157780258238E-191 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 16 1 1525 4 1 false 0.5009451246996103 0.5009451246996103 1.2095302863090285E-289 regulation_of_MAP_kinase_activity GO:0043405 12133 268 16 1 533 1 3 false 0.5028142589118941 0.5028142589118941 1.0382438249699724E-159 small_molecule_metabolic_process GO:0044281 12133 2423 16 4 2877 4 1 false 0.502903145430424 0.502903145430424 0.0 cellular_protein_complex_assembly GO:0043623 12133 284 16 1 958 2 2 false 0.5052366585734948 0.5052366585734948 4.57678794545446E-252 activation_of_immune_response GO:0002253 12133 341 16 1 1618 3 2 false 0.5086150365369692 0.5086150365369692 0.0 protein_polymerization GO:0051258 12133 145 16 1 284 1 1 false 0.5105633802817375 0.5105633802817375 7.244587792673789E-85 neuron_projection GO:0043005 12133 534 16 1 1043 1 2 false 0.5119846596357591 0.5119846596357591 5.7946905775E-313 microtubule_cytoskeleton GO:0015630 12133 734 16 1 1430 1 1 false 0.5132867132864838 0.5132867132864838 0.0 RNA_splicing GO:0008380 12133 307 16 2 601 3 1 false 0.5162475173540857 0.5162475173540857 4.262015823312228E-180 dendrite GO:0030425 12133 276 16 1 534 1 1 false 0.516853932584358 0.516853932584358 6.975042602902724E-160 response_to_growth_factor_stimulus GO:0070848 12133 545 16 1 1783 2 1 false 0.5180174651098625 0.5180174651098625 0.0 intracellular_signal_transduction GO:0035556 12133 1813 16 3 3547 5 1 false 0.5208851917551968 0.5208851917551968 0.0 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 16 1 1541 2 3 false 0.5225060468406766 0.5225060468406766 0.0 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 16 2 10311 16 3 false 0.5280412572608499 0.5280412572608499 0.0 regulation_of_protein_kinase_activity GO:0045859 12133 621 16 1 1169 1 3 false 0.5312232677504198 0.5312232677504198 0.0 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 16 2 803 2 1 false 0.532308705198418 0.532308705198418 1.0286714317927864E-202 positive_regulation_of_biological_process GO:0048518 12133 3081 16 5 10446 16 2 false 0.5323853248645004 0.5323853248645004 0.0 MAP_kinase_activity GO:0004707 12133 277 16 1 520 1 2 false 0.5326923076922037 0.5326923076922037 2.5282679507054518E-155 regulation_of_programmed_cell_death GO:0043067 12133 1031 16 2 1410 2 2 false 0.5345222455445995 0.5345222455445995 0.0 protein_binding_transcription_factor_activity GO:0000988 12133 488 16 1 10311 16 3 false 0.5399104593077949 0.5399104593077949 0.0 nuclear_speck GO:0016607 12133 147 16 1 272 1 1 false 0.5404411764705604 0.5404411764705604 6.6218564870724965E-81 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 16 2 381 3 2 false 0.5414055571898022 0.5414055571898022 8.855041133991382E-114 embryo_development GO:0009790 12133 768 16 1 3347 3 3 false 0.5426266006475251 0.5426266006475251 0.0 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 16 1 129 1 1 false 0.5426356589147338 0.5426356589147338 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 16 1 129 1 1 false 0.5426356589147338 0.5426356589147338 3.3394798770258706E-38 cytoplasmic_vesicle_part GO:0044433 12133 366 16 1 7185 15 3 false 0.5438920425436579 0.5438920425436579 0.0 regulation_of_apoptotic_process GO:0042981 12133 1019 16 2 1381 2 2 false 0.5443136143732132 0.5443136143732132 0.0 lipid_binding GO:0008289 12133 571 16 1 8962 12 1 false 0.5463848592828748 0.5463848592828748 0.0 proteolysis GO:0006508 12133 732 16 3 3431 13 1 false 0.5469264312885038 0.5469264312885038 0.0 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 16 1 129 1 1 false 0.5503875968992259 0.5503875968992259 4.0186961232005657E-38 transcription_coactivator_activity GO:0003713 12133 264 16 1 478 1 2 false 0.5523012552300889 0.5523012552300889 4.798051856605128E-142 activation_of_MAPK_activity GO:0000187 12133 158 16 1 286 1 2 false 0.5524475524475345 0.5524475524475345 8.207976102051858E-85 protein_folding GO:0006457 12133 183 16 1 3038 13 1 false 0.554834284582969 0.554834284582969 1.582632936584301E-299 positive_regulation_of_immune_system_process GO:0002684 12133 540 16 1 3595 5 3 false 0.5570569714898044 0.5570569714898044 0.0 chromatin GO:0000785 12133 287 16 1 512 1 1 false 0.5605468749999285 0.5605468749999285 9.050120143931621E-152 actin_filament-based_process GO:0030029 12133 431 16 1 7541 14 1 false 0.5616195709740853 0.5616195709740853 0.0 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 16 1 53 1 2 false 0.5660377358490526 0.5660377358490526 1.6040955778771873E-15 response_to_organic_substance GO:0010033 12133 1783 16 2 2369 2 1 false 0.5663857055664382 0.5663857055664382 0.0 response_to_abiotic_stimulus GO:0009628 12133 676 16 1 5200 6 1 false 0.5665608082586855 0.5665608082586855 0.0 regulation_of_cell_cycle_process GO:0010564 12133 382 16 2 1096 5 2 false 0.5691224846959375 0.5691224846959375 7.137372224746455E-307 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 16 2 4597 5 2 false 0.5695959955263019 0.5695959955263019 0.0 ion_transmembrane_transport GO:0034220 12133 556 16 1 970 1 2 false 0.5731958762885236 0.5731958762885236 1.3121997139332702E-286 organophosphate_metabolic_process GO:0019637 12133 1549 16 3 7521 14 2 false 0.5742076877214704 0.5742076877214704 0.0 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 16 1 309 1 2 false 0.5760517799352067 0.5760517799352067 7.558729588417702E-91 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 16 1 129 1 1 false 0.581395348837217 0.581395348837217 1.1512773005265922E-37 regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032434 12133 57 16 1 227 3 2 false 0.5818538588489612 0.5818538588489612 4.5524072103258975E-55 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 16 3 3771 14 4 false 0.5862962550630144 0.5862962550630144 0.0 regulatory_region_DNA_binding GO:0000975 12133 1169 16 2 2091 3 2 false 0.588223730942481 0.588223730942481 0.0 purine_nucleoside_metabolic_process GO:0042278 12133 1054 16 3 1257 3 2 false 0.589272371014592 0.589272371014592 1.399683863089717E-240 nucleobase-containing_compound_transport GO:0015931 12133 135 16 1 1584 10 2 false 0.5907603029769588 0.5907603029769588 1.0378441909200412E-199 activation_of_protein_kinase_activity GO:0032147 12133 247 16 1 417 1 1 false 0.5923261390887407 0.5923261390887407 9.475379918718814E-122 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 16 3 4044 14 3 false 0.5924069734969608 0.5924069734969608 0.0 ribosome_biogenesis GO:0042254 12133 144 16 1 243 1 1 false 0.5925925925925675 0.5925925925925675 8.984879194471426E-71 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 16 2 136 2 2 false 0.5947712418300675 0.5947712418300675 2.4301849830786213E-31 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 16 4 6129 14 3 false 0.5952838083232713 0.5952838083232713 0.0 steroid_hormone_receptor_binding GO:0035258 12133 62 16 1 104 1 1 false 0.5961538461538246 0.5961538461538246 4.2931773052216616E-30 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 16 3 7451 14 1 false 0.5981895945577447 0.5981895945577447 0.0 endosome GO:0005768 12133 455 16 1 8213 16 2 false 0.5985840729783152 0.5985840729783152 0.0 RNA_localization GO:0006403 12133 131 16 1 1642 11 1 false 0.6004808520147551 0.6004808520147551 1.0675246049472868E-197 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 16 2 90 2 3 false 0.6029962546816539 0.6029962546816539 1.9615250672171495E-20 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 16 1 129 1 1 false 0.6046511627907161 0.6046511627907161 3.5310664374642874E-37 receptor_binding GO:0005102 12133 918 16 1 6397 6 1 false 0.6053801128566125 0.6053801128566125 0.0 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 16 3 3547 5 1 false 0.6056615348137224 0.6056615348137224 0.0 androgen_receptor_signaling_pathway GO:0030521 12133 62 16 1 102 1 1 false 0.6078431372548947 0.6078431372548947 2.6706454874295595E-29 DNA-dependent_transcription,_initiation GO:0006352 12133 225 16 1 2751 11 2 false 0.60952354679491 0.60952354679491 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 16 1 701 1 2 false 0.6119828815976278 0.6119828815976278 1.5434745144062482E-202 ubiquitin-protein_ligase_activity GO:0004842 12133 321 16 2 558 3 2 false 0.6122489510563357 0.6122489510563357 1.7708856343357755E-164 androgen_receptor_binding GO:0050681 12133 38 16 1 62 1 1 false 0.6129032258064553 0.6129032258064553 1.0311688046013243E-17 regulation_of_catalytic_activity GO:0050790 12133 1692 16 2 6953 8 3 false 0.6162553380203755 0.6162553380203755 0.0 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 16 1 129 1 1 false 0.6201550387596937 0.6201550387596937 8.751505837166389E-37 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 16 1 768 1 1 false 0.6210937499998362 0.6210937499998362 1.6461815804374103E-220 positive_regulation_of_cell_proliferation GO:0008284 12133 558 16 1 3155 5 3 false 0.6223696830049462 0.6223696830049462 0.0 MAPK_cascade GO:0000165 12133 502 16 1 806 1 1 false 0.6228287841190995 0.6228287841190995 3.7900857366173457E-231 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 16 1 252 1 2 false 0.6230158730158346 0.6230158730158346 5.925442745937436E-72 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 16 1 971 11 2 false 0.6231039764720075 0.6231039764720075 1.7939571902377886E-121 nuclear_import GO:0051170 12133 203 16 1 2389 11 3 false 0.6242986627708214 0.6242986627708214 7.452348105569065E-301 ncRNA_metabolic_process GO:0034660 12133 258 16 1 3294 12 1 false 0.6248570440847117 0.6248570440847117 0.0 in_utero_embryonic_development GO:0001701 12133 295 16 1 471 1 1 false 0.6263269639064891 0.6263269639064891 1.719393530200133E-134 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 16 1 1399 2 3 false 0.6266646623730255 0.6266646623730255 0.0 negative_regulation_of_apoptotic_process GO:0043066 12133 537 16 1 1377 2 3 false 0.6280463089635778 0.6280463089635778 0.0 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 16 1 178 1 1 false 0.629213483146089 0.629213483146089 1.7238002808689451E-50 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 16 1 1356 2 2 false 0.6309135834727317 0.6309135834727317 0.0 response_to_stress GO:0006950 12133 2540 16 3 5200 6 1 false 0.6344551262454652 0.6344551262454652 0.0 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 16 1 129 1 1 false 0.635658914728704 0.635658914728704 2.4714073881998435E-36 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 16 9 106 9 2 false 0.635933164816916 0.635933164816916 9.867686559172291E-9 neuron_part GO:0097458 12133 612 16 1 9983 16 1 false 0.6368746488757535 0.6368746488757535 0.0 ncRNA_processing GO:0034470 12133 186 16 1 649 3 2 false 0.6375902203515856 0.6375902203515856 4.048832162241149E-168 egress_of_virus_within_host_cell GO:0046788 12133 11 16 1 28 2 2 false 0.640211640211643 0.640211640211643 4.656755228837597E-8 enzyme_binding GO:0019899 12133 1005 16 1 6397 6 1 false 0.6415312764109995 0.6415312764109995 0.0 protein_import GO:0017038 12133 225 16 1 2509 11 2 false 0.6450156412311561 0.6450156412311561 0.0 purine_nucleoside_catabolic_process GO:0006152 12133 939 16 3 1085 3 3 false 0.6479187446689437 0.6479187446689437 2.1746006434797338E-185 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 16 1 1350 2 4 false 0.6490129863000775 0.6490129863000775 0.0 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 16 1 2776 4 3 false 0.6496955754864564 0.6496955754864564 0.0 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 16 1 1813 3 1 false 0.6597510000674004 0.6597510000674004 0.0 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 16 2 86 2 2 false 0.6607387140902996 0.6607387140902996 1.0344828145516245E-17 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 16 2 81 2 2 false 0.6620370370370483 0.6620370370370483 1.2278945146862784E-16 purine-containing_compound_metabolic_process GO:0072521 12133 1232 16 3 5323 14 5 false 0.662432306420875 0.662432306420875 0.0 cytoplasmic_vesicle_membrane GO:0030659 12133 302 16 1 719 2 3 false 0.6639715482278123 0.6639715482278123 1.2351303462379864E-211 PML_body_organization GO:0030578 12133 4 16 1 6 1 1 false 0.6666666666666662 0.6666666666666662 0.06666666666666664 cellular_process GO:0009987 12133 9675 16 15 10446 16 1 false 0.6670890859356574 0.6670890859356574 0.0 positive_regulation_of_signaling GO:0023056 12133 817 16 1 4861 6 3 false 0.6686841714187725 0.6686841714187725 0.0 protein_complex_biogenesis GO:0070271 12133 746 16 2 1525 4 1 false 0.6713326585001054 0.6713326585001054 0.0 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 16 1 587 2 2 false 0.6727735753615924 0.6727735753615924 2.854325455984618E-173 positive_regulation_of_cell_communication GO:0010647 12133 820 16 1 4819 6 3 false 0.6736456228167944 0.6736456228167944 0.0 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 16 1 1546 2 3 false 0.6739446614504268 0.6739446614504268 0.0 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 16 3 5303 14 3 false 0.6742800431807661 0.6742800431807661 0.0 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 16 1 3702 6 3 false 0.6800777636819442 0.6800777636819442 0.0 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 16 2 185 2 1 false 0.6831962397181021 0.6831962397181021 1.2806047113744547E-36 ribonucleoside_catabolic_process GO:0042454 12133 946 16 3 1073 3 2 false 0.6850321606152967 0.6850321606152967 9.25790942536024E-169 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 16 3 5657 14 2 false 0.6857511260625042 0.6857511260625042 0.0 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 16 3 1054 3 2 false 0.6911364851424968 0.6911364851424968 2.3625686453162704E-163 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 16 3 1060 3 3 false 0.6948971467392391 0.6948971467392391 8.715047292960447E-163 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 16 9 181 9 1 false 0.695418000696852 0.695418000696852 8.905994863592909E-13 hydrolase_activity GO:0016787 12133 2556 16 3 4901 6 1 false 0.6958054957494411 0.6958054957494411 0.0 protein_serine/threonine_kinase_activity GO:0004674 12133 709 16 1 1014 1 1 false 0.6992110453650483 0.6992110453650483 1.8231541307779663E-268 carboxylic_acid_metabolic_process GO:0019752 12133 614 16 1 7453 14 2 false 0.7002328188928022 0.7002328188928022 0.0 positive_regulation_of_signal_transduction GO:0009967 12133 782 16 1 3650 5 5 false 0.7007000248179879 0.7007000248179879 0.0 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 16 1 361 3 1 false 0.7037065615217533 0.7037065615217533 4.560830022372086E-99 negative_regulation_of_cell_death GO:0060548 12133 567 16 1 3054 6 3 false 0.7086912342062582 0.7086912342062582 0.0 enzyme_regulator_activity GO:0030234 12133 771 16 1 10257 16 3 false 0.7138519206272795 0.7138519206272795 0.0 response_to_endogenous_stimulus GO:0009719 12133 982 16 1 5200 6 1 false 0.7153393080930486 0.7153393080930486 0.0 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 16 1 982 1 1 false 0.716904276986021 0.716904276986021 2.6984349291053464E-253 regulation_of_protein_metabolic_process GO:0051246 12133 1388 16 3 5563 14 3 false 0.7177687480130637 0.7177687480130637 0.0 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 16 3 645 3 1 false 0.7192329577808879 0.7192329577808879 7.3138241320053254E-93 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 16 1 217 2 1 false 0.7203020993342898 0.7203020993342898 1.2933579260360868E-64 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 16 1 5778 6 3 false 0.7224808257464981 0.7224808257464981 0.0 cellular_component_organization GO:0016043 12133 3745 16 13 3839 13 1 false 0.7241295322981802 0.7241295322981802 4.153510440731863E-191 anatomical_structure_development GO:0048856 12133 3099 16 3 3447 3 1 false 0.7266050505262209 0.7266050505262209 0.0 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 16 1 1779 1 1 false 0.7329960652055553 0.7329960652055553 0.0 actin_cytoskeleton_organization GO:0030036 12133 373 16 1 768 2 2 false 0.7357976151671828 0.7357976151671828 3.0657297438498186E-230 cellular_protein_complex_disassembly GO:0043624 12133 149 16 9 154 9 1 false 0.736970396384362 0.736970396384362 1.4793035521715585E-9 purine_nucleotide_metabolic_process GO:0006163 12133 1208 16 3 1337 3 2 false 0.7373987228449017 0.7373987228449017 1.5771526523631757E-183 translation_elongation_factor_activity GO:0003746 12133 22 16 1 180 10 2 false 0.7381010119968567 0.7381010119968567 1.0368938565383413E-28 intracellular_organelle_lumen GO:0070013 12133 2919 16 7 5320 14 2 false 0.7383499974884966 0.7383499974884966 0.0 organelle_lumen GO:0043233 12133 2968 16 7 5401 14 2 false 0.7404525829084699 0.7404525829084699 0.0 organic_acid_metabolic_process GO:0006082 12133 676 16 1 7326 14 2 false 0.7424763365460629 0.7424763365460629 0.0 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 16 1 1730 3 2 false 0.7445918876771974 0.7445918876771974 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 16 1 6358 8 2 false 0.7454641114565755 0.7454641114565755 0.0 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 16 1 5027 14 3 false 0.7489866851357387 0.7489866851357387 0.0 protein_kinase_activity GO:0004672 12133 1014 16 1 1347 1 3 false 0.7527839643658618 0.7527839643658618 0.0 transmembrane_transport GO:0055085 12133 728 16 1 7606 14 2 false 0.7558081022055594 0.7558081022055594 0.0 chromosomal_part GO:0044427 12133 512 16 1 5337 14 2 false 0.7567715177738893 0.7567715177738893 0.0 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 16 6 8688 15 3 false 0.7579825755434977 0.7579825755434977 0.0 ribonucleotide_metabolic_process GO:0009259 12133 1202 16 3 1318 3 2 false 0.7583534146640842 0.7583534146640842 7.680938106405399E-170 kinase_activity GO:0016301 12133 1174 16 1 1546 1 2 false 0.7593790426910867 0.7593790426910867 0.0 organelle_organization GO:0006996 12133 2031 16 3 7663 14 2 false 0.760290594119462 0.760290594119462 0.0 organelle_membrane GO:0031090 12133 1619 16 2 9319 15 3 false 0.7629461619662661 0.7629461619662661 0.0 regulation_of_cellular_catabolic_process GO:0031329 12133 494 16 1 5000 14 3 false 0.7673900069889992 0.7673900069889992 0.0 JNK_cascade GO:0007254 12133 159 16 1 207 1 1 false 0.7681159420289673 0.7681159420289673 3.1556682987155503E-48 signaling GO:0023052 12133 3878 16 5 10446 16 1 false 0.7682406712192614 0.7682406712192614 0.0 membrane_invagination GO:0010324 12133 411 16 1 784 2 1 false 0.7739659082022576 0.7739659082022576 8.658368437912315E-235 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 16 2 185 2 1 false 0.7757344300823621 0.7757344300823621 5.464989090238489E-29 cellular_macromolecular_complex_assembly GO:0034622 12133 517 16 1 973 2 1 false 0.7806199484857734 0.7806199484857734 3.312522477266262E-291 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 16 3 1007 3 2 false 0.7849643103887629 0.7849643103887629 1.4040993054667365E-118 T_cell_receptor_signaling_pathway GO:0050852 12133 88 16 1 112 1 1 false 0.7857142857143178 0.7857142857143178 5.828412725788921E-25 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 16 2 71 2 3 false 0.785915492957749 0.785915492957749 9.399268641403064E-11 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 16 3 1006 3 2 false 0.789857749500738 0.789857749500738 2.1893990019353197E-116 negative_regulation_of_gene_expression GO:0010629 12133 817 16 2 3906 13 3 false 0.7904227988744911 0.7904227988744911 0.0 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 16 1 129 1 1 false 0.7906976744186143 0.7906976744186143 2.104544859412626E-28 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 16 1 312 1 1 false 0.7916666666666485 0.7916666666666485 8.216510305576978E-69 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 16 2 4429 13 3 false 0.792369067204117 0.792369067204117 0.0 membrane_organization GO:0061024 12133 787 16 2 3745 13 1 false 0.792855389081651 0.792855389081651 0.0 regulation_of_protein_phosphorylation GO:0001932 12133 787 16 1 1444 2 3 false 0.7931594496696428 0.7931594496696428 0.0 acid-amino_acid_ligase_activity GO:0016881 12133 351 16 3 379 3 1 false 0.7938313165316235 0.7938313165316235 5.324332733169013E-43 activating_transcription_factor_binding GO:0033613 12133 294 16 1 715 3 1 false 0.7964591303422026 0.7964591303422026 1.6086726333731214E-209 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 16 3 1002 3 3 false 0.7967858728093028 0.7967858728093028 5.68242981185093E-113 single-organism_metabolic_process GO:0044710 12133 2877 16 4 8027 14 1 false 0.7986213936197747 0.7986213936197747 0.0 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 16 2 4298 13 4 false 0.7999720411715439 0.7999720411715439 0.0 transport GO:0006810 12133 2783 16 12 2833 12 1 false 0.807267200040446 0.807267200040446 1.147202604491021E-108 cell_projection GO:0042995 12133 976 16 1 9983 16 1 false 0.8074519326891607 0.8074519326891607 0.0 cell_death GO:0008219 12133 1525 16 2 7542 14 2 false 0.8077974948416251 0.8077974948416251 0.0 death GO:0016265 12133 1528 16 2 8052 15 1 false 0.8081181620166169 0.8081181620166169 0.0 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 16 2 5558 14 3 false 0.808843613506168 0.808843613506168 0.0 nucleotide_binding GO:0000166 12133 1997 16 4 2103 4 2 false 0.8129977137425188 0.8129977137425188 1.0169073992212018E-181 mitosis GO:0007067 12133 326 16 1 953 4 2 false 0.813244883125815 0.813244883125815 4.8424843971573165E-265 nucleoside_phosphate_binding GO:1901265 12133 1998 16 4 4407 11 2 false 0.8152974894874229 0.8152974894874229 0.0 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 16 2 3453 12 4 false 0.8228004843842606 0.8228004843842606 0.0 regulation_of_metabolic_process GO:0019222 12133 4469 16 6 9189 15 2 false 0.8229168646929843 0.8229168646929843 0.0 programmed_cell_death GO:0012501 12133 1385 16 2 1525 2 1 false 0.8247665763094012 0.8247665763094012 2.142172117700311E-202 cellular_component_biogenesis GO:0044085 12133 1525 16 4 3839 13 1 false 0.8267081995202558 0.8267081995202558 0.0 molecular_transducer_activity GO:0060089 12133 1070 16 1 10257 16 1 false 0.828658971727656 0.828658971727656 0.0 intracellular_protein_kinase_cascade GO:0007243 12133 806 16 1 1813 3 1 false 0.8288727917882903 0.8288727917882903 0.0 nucleoside_binding GO:0001882 12133 1639 16 3 4455 11 3 false 0.8327591326466949 0.8327591326466949 0.0 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 16 2 3780 13 4 false 0.833139229559126 0.833139229559126 0.0 regulation_of_primary_metabolic_process GO:0080090 12133 3921 16 6 7507 14 2 false 0.8339919411601389 0.8339919411601389 0.0 signal_transducer_activity GO:0004871 12133 1070 16 1 3547 5 2 false 0.8341197668695854 0.8341197668695854 0.0 membrane-bounded_vesicle GO:0031988 12133 762 16 2 834 2 1 false 0.8346964685154482 0.8346964685154482 6.820230733401612E-106 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 16 1 1304 1 1 false 0.8351226993861972 0.8351226993861972 1.004636319027547E-252 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 16 2 165 2 2 false 0.8370288248337823 0.8370288248337823 1.3866478491946915E-20 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 16 2 5151 14 4 false 0.8374721497277023 0.8374721497277023 0.0 catalytic_activity GO:0003824 12133 4901 16 6 10478 16 2 false 0.839928073441542 0.839928073441542 0.0 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 16 6 6094 14 2 false 0.8423323158245352 0.8423323158245352 0.0 structural_constituent_of_cytoskeleton GO:0005200 12133 88 16 1 526 10 1 false 0.842486264797468 0.842486264797468 1.4915391741340796E-102 response_to_chemical_stimulus GO:0042221 12133 2369 16 2 5200 6 1 false 0.8433727910340683 0.8433727910340683 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 16 3 400 3 2 false 0.8435387463631769 0.8435387463631769 1.150456419433401E-36 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 16 1 2595 3 2 false 0.8438006777628793 0.8438006777628793 0.0 nuclear_export GO:0051168 12133 116 16 1 688 10 2 false 0.8443116234259405 0.8443116234259405 6.892155989004194E-135 protein_phosphorylation GO:0006468 12133 1195 16 1 2577 3 2 false 0.8459210545448961 0.8459210545448961 0.0 large_ribosomal_subunit GO:0015934 12133 73 16 4 132 9 1 false 0.8473283073248319 0.8473283073248319 5.5437540818743186E-39 interphase GO:0051325 12133 233 16 2 253 2 1 false 0.8478574565529252 0.8478574565529252 4.555981744751407E-30 immune_response-activating_signal_transduction GO:0002757 12133 299 16 1 352 1 2 false 0.849431818181766 0.849431818181766 2.8561568566531905E-64 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 16 2 3847 12 4 false 0.8501952689041998 0.8501952689041998 0.0 nuclear_hormone_receptor_binding GO:0035257 12133 104 16 1 122 1 1 false 0.8524590163934733 0.8524590163934733 6.677251530520905E-22 phosphorus_metabolic_process GO:0006793 12133 2805 16 4 7256 14 1 false 0.8538337472203654 0.8538337472203654 0.0 purine_nucleotide_binding GO:0017076 12133 1650 16 3 1997 4 1 false 0.8582500685967807 0.8582500685967807 0.0 regulation_of_protein_localization GO:0032880 12133 349 16 1 2148 11 2 false 0.8584855708463832 0.8584855708463832 0.0 ribonucleotide_binding GO:0032553 12133 1651 16 3 1997 4 1 false 0.8589625200704221 0.8589625200704221 0.0 interaction_with_host GO:0051701 12133 387 16 2 417 2 2 false 0.86113032650842 0.86113032650842 1.9217516081652173E-46 anatomical_structure_morphogenesis GO:0009653 12133 1664 16 1 3447 3 2 false 0.8617143295671161 0.8617143295671161 0.0 nitrogen_compound_transport GO:0071705 12133 428 16 1 2783 12 1 false 0.8657683338575584 0.8657683338575584 0.0 cell_cycle_checkpoint GO:0000075 12133 202 16 2 217 2 1 false 0.8662314388120638 0.8662314388120638 1.925703524045096E-23 positive_regulation_of_gene_expression GO:0010628 12133 1008 16 2 4103 13 3 false 0.8664123435029487 0.8664123435029487 0.0 membrane_part GO:0044425 12133 2995 16 3 10701 16 2 false 0.8676426009573348 0.8676426009573348 0.0 small_conjugating_protein_ligase_activity GO:0019787 12133 335 16 3 351 3 1 false 0.8690303011221425 0.8690303011221425 5.577217121688537E-28 toll-like_receptor_signaling_pathway GO:0002224 12133 129 16 1 147 1 1 false 0.8775510204081407 0.8775510204081407 1.843896992838607E-23 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 16 1 6622 8 1 false 0.8783041801506669 0.8783041801506669 0.0 nucleolus GO:0005730 12133 1357 16 3 4208 14 3 false 0.8789648548591794 0.8789648548591794 0.0 regulation_of_cellular_process GO:0050794 12133 6304 16 8 9757 15 2 false 0.8804991048099208 0.8804991048099208 0.0 female_pregnancy GO:0007565 12133 126 16 1 712 11 2 false 0.8845747220013449 0.8845747220013449 1.1918411623730802E-143 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 16 1 2643 3 1 false 0.8870791735962893 0.8870791735962893 0.0 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 16 6 6638 14 2 false 0.8886017782394261 0.8886017782394261 0.0 intrinsic_to_membrane GO:0031224 12133 2375 16 2 2995 3 1 false 0.8892774043792759 0.8892774043792759 0.0 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 16 2 4582 13 3 false 0.8894702613145735 0.8894702613145735 0.0 response_to_stimulus GO:0050896 12133 5200 16 6 10446 16 1 false 0.8918561430497478 0.8918561430497478 0.0 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 16 2 4456 13 4 false 0.8942784992320846 0.8942784992320846 0.0 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 16 1 5183 8 2 false 0.896141908983708 0.896141908983708 0.0 'de_novo'_posttranslational_protein_folding GO:0051084 12133 46 16 1 51 1 1 false 0.9019607843137332 0.9019607843137332 4.2570219577192243E-7 cellular_component_assembly GO:0022607 12133 1392 16 3 3836 13 2 false 0.9043061668282839 0.9043061668282839 0.0 system_development GO:0048731 12133 2686 16 2 3304 3 2 false 0.9082159165033996 0.9082159165033996 0.0 mitochondrion GO:0005739 12133 1138 16 1 8213 16 2 false 0.9082572200040764 0.9082572200040764 0.0 regulation_of_cellular_component_organization GO:0051128 12133 1152 16 1 7336 14 2 false 0.9087280574832333 0.9087280574832333 0.0 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 16 2 3972 13 4 false 0.9092703331944655 0.9092703331944655 0.0 nucleoplasm_part GO:0044451 12133 805 16 1 2767 7 2 false 0.9101591209607092 0.9101591209607092 0.0 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 16 1 2780 4 2 false 0.9119584330715285 0.9119584330715285 0.0 chromosome GO:0005694 12133 592 16 1 3226 12 1 false 0.912619478184975 0.912619478184975 0.0 regulation_of_biological_process GO:0050789 12133 6622 16 8 10446 16 2 false 0.9130162911173669 0.9130162911173669 0.0 regulation_of_localization GO:0032879 12133 1242 16 1 7621 14 2 false 0.9173280885075852 0.9173280885075852 0.0 multicellular_organismal_development GO:0007275 12133 3069 16 2 4373 4 2 false 0.9177539716167384 0.9177539716167384 0.0 nucleic_acid_transport GO:0050657 12133 124 16 1 135 1 1 false 0.9185185185185545 0.9185185185185545 2.2345648964967124E-16 protein_processing GO:0016485 12133 113 16 1 123 1 1 false 0.918699186991829 0.918699186991829 6.665856545071852E-15 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 16 5 4544 12 3 false 0.9187772211566834 0.9187772211566834 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I,_TAP-dependent GO:0002479 12133 70 16 2 73 2 1 false 0.9189497716895059 0.9189497716895059 1.607820438613435E-5 single_organism_signaling GO:0044700 12133 3878 16 5 8052 15 2 false 0.9221734731706687 0.9221734731706687 0.0 ion_binding GO:0043167 12133 4448 16 4 8962 12 1 false 0.9235136473267878 0.9235136473267878 0.0 nuclear_division GO:0000280 12133 326 16 1 351 1 1 false 0.9287749287750802 0.9287749287750802 8.671827254018066E-39 cell_proliferation GO:0008283 12133 1316 16 1 8052 15 1 false 0.9313932582069546 0.9313932582069546 0.0 transferase_activity GO:0016740 12133 1779 16 1 4901 6 1 false 0.9332992014602245 0.9332992014602245 0.0 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 16 3 1218 3 2 false 0.9372674542586665 0.9372674542586665 3.12960829510125E-54 developmental_process GO:0032502 12133 3447 16 3 10446 16 1 false 0.9374794080984883 0.9374794080984883 0.0 cell_communication GO:0007154 12133 3962 16 5 7541 14 1 false 0.9376514587210358 0.9376514587210358 0.0 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 16 2 2849 9 1 false 0.9376843737133687 0.9376843737133687 0.0 nucleoside-triphosphatase_activity GO:0017111 12133 1059 16 3 1080 3 1 false 0.9427415623200115 0.9427415623200115 1.2343281293318376E-44 cytoskeletal_part GO:0044430 12133 1031 16 1 5573 14 2 false 0.9431669971696475 0.9431669971696475 0.0 phosphorylation GO:0016310 12133 1421 16 1 2776 4 1 false 0.943363856661895 0.943363856661895 0.0 response_to_decreased_oxygen_levels GO:0036293 12133 202 16 1 214 1 1 false 0.9439252336448956 0.9439252336448956 7.108512362452622E-20 biological_regulation GO:0065007 12133 6908 16 8 10446 16 1 false 0.945071223007844 0.945071223007844 0.0 membrane GO:0016020 12133 4398 16 4 10701 16 1 false 0.9453871271723859 0.9453871271723859 0.0 transcription_cofactor_activity GO:0003712 12133 456 16 1 482 1 2 false 0.9460580912862344 0.9460580912862344 1.3948726648763881E-43 organ_development GO:0048513 12133 1929 16 1 3099 3 2 false 0.946272204599508 0.946272204599508 0.0 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 16 3 1072 3 2 false 0.947717266568648 0.947717266568648 3.811291228230986E-41 cellular_response_to_stimulus GO:0051716 12133 4236 16 5 7871 14 2 false 0.9487025331903772 0.9487025331903772 0.0 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 16 3 3120 5 4 false 0.9495682726098498 0.9495682726098498 0.0 integral_to_membrane GO:0016021 12133 2318 16 2 2375 2 1 false 0.952566133110128 0.952566133110128 3.0839384482043954E-116 cell_periphery GO:0071944 12133 2667 16 2 9983 16 1 false 0.9528317583541671 0.9528317583541671 0.0 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 16 3 378 3 1 false 0.9530102651893163 0.9530102651893163 2.5686196448553377E-13 binding GO:0005488 12133 8962 16 12 10257 16 1 false 0.957907772802348 0.957907772802348 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 16 4 2805 4 1 false 0.959260743642875 0.959260743642875 1.0460685646312495E-69 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 16 1 723 3 2 false 0.9594736751240371 0.9594736751240371 2.0953844092707462E-201 interspecies_interaction_between_organisms GO:0044419 12133 417 16 2 1180 12 1 false 0.9603515027771816 0.9603515027771816 0.0 organophosphate_catabolic_process GO:0046434 12133 1000 16 3 2495 14 2 false 0.9611171753006579 0.9611171753006579 0.0 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 16 1 78 1 1 false 0.961538461538445 0.961538461538445 1.3144749986854762E-5 macromolecule_modification GO:0043412 12133 2461 16 3 6052 14 1 false 0.9643939343798169 0.9643939343798169 0.0 purine_ribonucleotide_binding GO:0032555 12133 1641 16 3 1660 3 2 false 0.9660339344226436 0.9660339344226436 8.870449707822982E-45 ribonucleoside_metabolic_process GO:0009119 12133 1071 16 3 1083 3 1 false 0.9670959006082696 0.9670959006082696 1.9559437642804265E-28 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 16 3 2517 14 2 false 0.9673754436479105 0.9673754436479105 0.0 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 16 5 5532 14 4 false 0.9683499699535434 0.9683499699535434 0.0 protein_binding GO:0005515 12133 6397 16 6 8962 12 1 false 0.9700532285827773 0.9700532285827773 0.0 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 16 3 1014 3 1 false 0.9706763636218662 0.9706763636218662 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 16 3 1014 3 1 false 0.9706763636218662 0.9706763636218662 3.301546202575714E-24 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 16 3 2643 14 2 false 0.9755215085884272 0.9755215085884272 0.0 nuclear_transport GO:0051169 12133 331 16 1 1148 11 1 false 0.9767410640350204 0.9767410640350204 1.3196682196913852E-298 protein_import_into_nucleus GO:0006606 12133 200 16 1 690 11 5 false 0.9775863701858403 0.9775863701858403 1.1794689955817937E-179 metal_ion_binding GO:0046872 12133 2699 16 1 2758 1 1 false 0.9786076867315662 0.9786076867315662 2.6200760259069314E-123 cation_binding GO:0043169 12133 2758 16 1 4448 4 1 false 0.9792063491622687 0.9792063491622687 0.0 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 16 2 1225 3 2 false 0.9793779817736419 0.9793779817736419 5.928244845001387E-155 glycosyl_compound_catabolic_process GO:1901658 12133 956 16 3 2175 14 2 false 0.9798057928500692 0.9798057928500692 0.0 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 16 2 199 2 1 false 0.9799502563321717 0.9799502563321717 5.075884472869322E-5 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 16 3 1007 3 2 false 0.9822138475969335 0.9822138475969335 7.008686204750717E-16 viral_reproduction GO:0016032 12133 633 16 11 634 11 1 false 0.982649842271585 0.982649842271585 0.0015772870662463625 apoptotic_process GO:0006915 12133 1373 16 2 1385 2 1 false 0.9827403434810396 0.9827403434810396 1.0085392941984968E-29 multicellular_organismal_process GO:0032501 12133 4223 16 3 10446 16 1 false 0.9831729518856469 0.9831729518856469 0.0 single-organism_developmental_process GO:0044767 12133 2776 16 2 8064 15 2 false 0.984249180589531 0.984249180589531 0.0 purine_nucleoside_binding GO:0001883 12133 1631 16 3 1639 3 1 false 0.9854194257449641 0.9854194257449641 7.876250956196666E-22 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 16 1 149 1 1 false 0.9865771812081086 0.9865771812081086 9.06947215672054E-5 oxoacid_metabolic_process GO:0043436 12133 667 16 1 676 1 1 false 0.9866863905329417 0.9866863905329417 1.2985791548492531E-20 protein_localization_to_nucleus GO:0034504 12133 233 16 2 516 11 1 false 0.9871711181385998 0.9871711181385998 1.4955266190313754E-153 chordate_embryonic_development GO:0043009 12133 471 16 1 477 1 1 false 0.9874213836479633 0.9874213836479633 6.308586670641318E-14 nucleocytoplasmic_transport GO:0006913 12133 327 16 1 331 1 1 false 0.9879154078549209 0.9879154078549209 2.036102168267257E-9 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 16 3 1085 3 1 false 0.9889706819254394 0.9889706819254394 1.7413918354446858E-11 purine_ribonucleoside_binding GO:0032550 12133 1629 16 3 1635 3 2 false 0.9890244859858223 0.9890244859858223 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 16 3 1639 3 1 false 0.9890511899355285 0.9890511899355285 3.7483303336303164E-17 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 16 3 672 11 1 false 0.9895198407083554 0.9895198407083554 6.935915883902889E-199 vesicle-mediated_transport GO:0016192 12133 895 16 1 2783 12 1 false 0.9906034967166482 0.9906034967166482 0.0 plasma_membrane GO:0005886 12133 2594 16 1 10252 16 3 false 0.9906419731829617 0.9906419731829617 0.0 regulation_of_gene_expression GO:0010468 12133 2935 16 5 4361 13 2 false 0.9924181906401802 0.9924181906401802 0.0 protein_ubiquitination GO:0016567 12133 548 16 2 578 3 1 false 0.9924276724660142 0.9924276724660142 7.913703273197485E-51 ion_transport GO:0006811 12133 833 16 1 2323 11 1 false 0.9925400338591115 0.9925400338591115 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 16 3 1319 3 1 false 0.9954545506831779 0.9954545506831779 1.1504554077729292E-6 regulation_of_biosynthetic_process GO:0009889 12133 3012 16 3 5483 13 2 false 0.9958387418382857 0.9958387418382857 0.0 purine-containing_compound_catabolic_process GO:0072523 12133 959 16 3 1651 12 6 false 0.9958728420664125 0.9958728420664125 0.0 single-multicellular_organism_process GO:0044707 12133 4095 16 3 8057 15 2 false 0.9969632055574016 0.9969632055574016 0.0 pyrophosphatase_activity GO:0016462 12133 1080 16 3 1081 3 1 false 0.997224791858996 0.997224791858996 9.250693802031629E-4 protein_targeting_to_nucleus GO:0044744 12133 200 16 1 443 10 1 false 0.9977355327415174 0.9977355327415174 9.352491047681514E-132 response_to_other_organism GO:0051707 12133 475 16 1 1194 12 2 false 0.9978087169348889 0.9978087169348889 0.0 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 16 3 1587 12 3 false 0.9979520987641823 0.9979520987641823 0.0 DNA_binding GO:0003677 12133 2091 16 3 2849 9 1 false 0.9980300006373563 0.9980300006373563 0.0 virus-host_interaction GO:0019048 12133 355 16 2 588 10 2 false 0.9985720375872505 0.9985720375872505 1.0104535019427035E-170 nucleoside_catabolic_process GO:0009164 12133 952 16 3 1516 12 5 false 0.9985855053023361 0.9985855053023361 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 16 3 4972 13 3 false 0.9987321705003489 0.9987321705003489 0.0 cytoskeleton GO:0005856 12133 1430 16 1 3226 12 1 false 0.9991278211090504 0.9991278211090504 0.0 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 16 3 4395 13 3 false 0.9996041700281977 0.9996041700281977 0.0 transcription,_DNA-dependent GO:0006351 12133 2643 16 3 4063 13 3 false 0.999664105419918 0.999664105419918 0.0 macromolecular_complex_assembly GO:0065003 12133 973 16 2 1603 12 2 false 0.9997470298165058 0.9997470298165058 0.0 protein_complex_assembly GO:0006461 12133 743 16 2 1214 12 3 false 0.9997826227518699 0.9997826227518699 0.0 protein_modification_process GO:0036211 12133 2370 16 3 3518 13 2 false 0.9998331609789209 0.9998331609789209 0.0 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 16 9 7976 15 2 false 0.9998442657315124 0.9998442657315124 0.0 membrane-bounded_organelle GO:0043227 12133 7284 16 9 7980 15 1 false 0.9998715199500122 0.9998715199500122 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 16 3 3220 11 4 false 0.9999780979119466 0.9999780979119466 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 16 3 3611 12 3 false 0.9999787399972567 0.9999787399972567 0.0 cellular_protein_modification_process GO:0006464 12133 2370 16 3 3038 13 2 false 0.9999972737867475 0.9999972737867475 0.0 protein_complex GO:0043234 12133 2976 16 4 3462 15 1 false 0.9999999842275794 0.9999999842275794 0.0 GO:0000000 12133 11221 16 16 0 0 0 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 16 1 147 1 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 16 1 87 1 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 16 2 1169 2 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 16 2 417 2 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 16 1 124 1 2 true 1.0 1.0 1.0