ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min ribonucleoprotein_complex GO:0030529 12133 569 36 19 9264 35 2 false 1.1440665287671481E-14 1.1440665287671481E-14 0.0 translational_elongation GO:0006414 12133 121 36 12 3388 25 2 false 8.76834971944789E-12 8.76834971944789E-12 5.332026529203484E-226 translational_initiation GO:0006413 12133 160 36 11 7667 30 2 false 8.99030889362132E-12 8.99030889362132E-12 0.0 ribosomal_subunit GO:0044391 12133 132 36 11 7199 35 4 false 1.4857119905614135E-11 1.4857119905614135E-11 2.5906239763169356E-285 mRNA_metabolic_process GO:0016071 12133 573 36 22 3294 30 1 false 1.9954476478484495E-11 1.9954476478484495E-11 0.0 ribosome GO:0005840 12133 210 36 12 6755 31 3 false 5.0029772815129934E-11 5.0029772815129934E-11 0.0 cytosolic_part GO:0044445 12133 178 36 11 5117 24 2 false 1.1185728736749638E-10 1.1185728736749638E-10 0.0 multi-organism_cellular_process GO:0044764 12133 634 36 16 9702 35 2 false 1.1595324052053591E-10 1.1595324052053591E-10 0.0 viral_transcription GO:0019083 12133 145 36 11 2964 23 3 false 2.1536770022989266E-9 2.1536770022989266E-9 1.0927707330622845E-250 structural_molecule_activity GO:0005198 12133 526 36 13 10257 36 1 false 1.1401827351638695E-8 1.1401827351638695E-8 0.0 organelle_part GO:0044422 12133 5401 36 33 10701 35 2 false 2.3564456788819875E-8 2.3564456788819875E-8 0.0 RNA_binding GO:0003723 12133 763 36 19 2849 23 1 false 3.2008300018502185E-8 3.2008300018502185E-8 0.0 cellular_component_disassembly GO:0022411 12133 351 36 11 7663 30 2 false 3.974154940176453E-8 3.974154940176453E-8 0.0 cellular_process_involved_in_reproduction GO:0048610 12133 469 36 12 9699 35 2 false 4.288254496773126E-8 4.288254496773126E-8 0.0 protein_targeting_to_ER GO:0045047 12133 104 36 11 721 14 3 false 8.708404133461167E-8 8.708404133461167E-8 1.514347826459292E-128 RNA_catabolic_process GO:0006401 12133 203 36 11 4368 32 3 false 9.121268798631407E-8 9.121268798631407E-8 0.0 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 36 12 1239 15 2 false 1.2074359660249377E-7 1.2074359660249377E-7 4.427655683668096E-244 translational_termination GO:0006415 12133 92 36 11 513 13 2 false 2.0900948825761222E-7 2.0900948825761222E-7 3.4634519853301643E-104 reproductive_process GO:0022414 12133 1275 36 17 10446 36 2 false 2.3453280012562662E-7 2.3453280012562662E-7 0.0 reproduction GO:0000003 12133 1345 36 17 10446 36 1 false 5.110876264815684E-7 5.110876264815684E-7 0.0 multi-organism_process GO:0051704 12133 1180 36 16 10446 36 1 false 5.138311331438297E-7 5.138311331438297E-7 0.0 translation GO:0006412 12133 457 36 13 5433 33 3 false 1.0661125048318974E-6 1.0661125048318974E-6 0.0 protein_complex_disassembly GO:0043241 12133 154 36 11 1031 16 2 false 1.3275921941268513E-6 1.3275921941268513E-6 4.7545827865276796E-188 intracellular_organelle_part GO:0044446 12133 5320 36 33 9083 35 3 false 2.3101853145039937E-6 2.3101853145039937E-6 0.0 macromolecular_complex GO:0032991 12133 3462 36 25 10701 35 1 false 2.413779392992218E-6 2.413779392992218E-6 0.0 protein_targeting GO:0006605 12133 443 36 12 2378 17 2 false 3.816126231247955E-6 3.816126231247955E-6 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 36 23 10701 35 1 false 3.906856300575427E-6 3.906856300575427E-6 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 36 14 6457 35 3 false 4.416281113159503E-6 4.416281113159503E-6 0.0 macromolecular_complex_disassembly GO:0032984 12133 199 36 11 1380 18 2 false 5.471508770048476E-6 5.471508770048476E-6 1.9082717261040364E-246 heterocyclic_compound_binding GO:1901363 12133 4359 36 27 8962 31 1 false 8.628975026882027E-6 8.628975026882027E-6 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 36 11 516 14 1 false 9.76419615311383E-6 9.76419615311383E-6 8.917305549619806E-119 organic_cyclic_compound_binding GO:0097159 12133 4407 36 27 8962 31 1 false 1.1165689318102646E-5 1.1165689318102646E-5 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 36 33 7341 34 5 false 1.2689641175493443E-5 1.2689641175493443E-5 0.0 cellular_metabolic_process GO:0044237 12133 7256 36 35 10007 35 2 false 1.2704309588583138E-5 1.2704309588583138E-5 0.0 macromolecular_complex_subunit_organization GO:0043933 12133 1256 36 18 3745 23 1 false 1.35790703705027E-5 1.35790703705027E-5 0.0 cytosolic_ribosome GO:0022626 12133 92 36 11 296 12 2 false 1.5035416431156483E-5 1.5035416431156483E-5 4.2784789004852985E-79 macromolecule_catabolic_process GO:0009057 12133 820 36 14 6846 35 2 false 2.298496642401061E-5 2.298496642401061E-5 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 36 35 7569 35 2 false 2.7767654419794244E-5 2.7767654419794244E-5 0.0 protein_targeting_to_membrane GO:0006612 12133 145 36 11 443 12 1 false 3.0478151019461326E-5 3.0478151019461326E-5 5.648405296311656E-121 intracellular_transport GO:0046907 12133 1148 36 16 2815 18 2 false 3.231626727760293E-5 3.231626727760293E-5 0.0 catabolic_process GO:0009056 12133 2164 36 21 8027 35 1 false 3.931999478773238E-5 3.931999478773238E-5 0.0 structural_constituent_of_ribosome GO:0003735 12133 152 36 11 526 13 1 false 3.939467147810645E-5 3.939467147810645E-5 1.18011379183299E-136 cellular_catabolic_process GO:0044248 12133 1972 36 21 7289 35 2 false 4.1480458444225124E-5 4.1480458444225124E-5 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 36 21 7502 35 2 false 5.042907199442046E-5 5.042907199442046E-5 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 36 33 8027 35 1 false 6.151848723802239E-5 6.151848723802239E-5 0.0 cellular_localization GO:0051641 12133 1845 36 17 7707 29 2 false 6.571928385777054E-5 6.571928385777054E-5 0.0 cytosol GO:0005829 12133 2226 36 20 5117 24 1 false 7.164089858869159E-5 7.164089858869159E-5 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 36 18 5462 33 2 false 7.305115533763693E-5 7.305115533763693E-5 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 36 18 5528 33 2 false 7.637469007407663E-5 7.637469007407663E-5 0.0 Prp19_complex GO:0000974 12133 78 36 4 2976 10 1 false 8.140871180659742E-5 8.140871180659742E-5 3.570519754703887E-156 heterocycle_catabolic_process GO:0046700 12133 1243 36 18 5392 33 2 false 8.456313097796885E-5 8.456313097796885E-5 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 36 18 5388 33 2 false 9.139086095739246E-5 9.139086095739246E-5 0.0 cellular_macromolecule_localization GO:0070727 12133 918 36 15 2206 17 2 false 9.316101966877804E-5 9.316101966877804E-5 0.0 RNA_processing GO:0006396 12133 601 36 14 3762 31 2 false 1.1363532436275247E-4 1.1363532436275247E-4 0.0 viral_infectious_cycle GO:0019058 12133 213 36 13 557 15 1 false 1.350605745119929E-4 1.350605745119929E-4 3.455075709157513E-160 nucleic_acid_metabolic_process GO:0090304 12133 3799 36 30 6846 35 2 false 1.4405533849944907E-4 1.4405533849944907E-4 0.0 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 36 33 7451 35 1 false 1.7827676631974098E-4 1.7827676631974098E-4 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 36 33 7256 35 1 false 1.9836749207976666E-4 1.9836749207976666E-4 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 36 33 7256 35 1 false 2.0676412161977132E-4 2.0676412161977132E-4 0.0 viral_genome_expression GO:0019080 12133 153 36 11 557 15 2 false 2.3608967962889595E-4 2.3608967962889595E-4 1.6461772406083414E-141 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 36 18 4878 33 5 false 2.585132855193506E-4 2.585132855193506E-4 0.0 regulation_of_RNA_splicing GO:0043484 12133 52 36 4 3151 20 3 false 2.6298066036972516E-4 2.6298066036972516E-4 1.4828410310444421E-114 intracellular_protein_transport GO:0006886 12133 658 36 14 1672 17 3 false 3.4713113730720855E-4 3.4713113730720855E-4 0.0 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 36 33 7275 35 2 false 4.150070062163887E-4 4.150070062163887E-4 0.0 organelle GO:0043226 12133 7980 36 34 10701 35 1 false 4.4202314558773717E-4 4.4202314558773717E-4 0.0 RNA_metabolic_process GO:0016070 12133 3294 36 30 5627 35 2 false 5.173470292341653E-4 5.173470292341653E-4 0.0 macromolecule_metabolic_process GO:0043170 12133 6052 36 35 7451 35 1 false 6.7749775622927E-4 6.7749775622927E-4 0.0 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 36 23 10446 36 1 false 8.424674912818986E-4 8.424674912818986E-4 0.0 nucleus GO:0005634 12133 4764 36 26 7259 28 1 false 8.870235253259518E-4 8.870235253259518E-4 0.0 metabolic_process GO:0008152 12133 8027 36 35 10446 36 1 false 8.896479910838037E-4 8.896479910838037E-4 0.0 nuclear_part GO:0044428 12133 2767 36 23 6936 34 2 false 9.605985035175996E-4 9.605985035175996E-4 0.0 cellular_protein_localization GO:0034613 12133 914 36 15 1438 15 2 false 0.0010702138837806515 0.0010702138837806515 0.0 single-organism_transport GO:0044765 12133 2323 36 17 8134 30 2 false 0.001144575422568228 0.001144575422568228 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 36 23 7980 34 1 false 0.001197198054692631 0.001197198054692631 0.0 negative_regulation_of_RNA_splicing GO:0033119 12133 15 36 3 1037 16 3 false 0.0012270489825638548 0.0012270489825638548 8.39457188486895E-34 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 36 23 7958 34 2 false 0.0012520596526983496 0.0012520596526983496 0.0 positive_regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033145 12133 9 36 2 856 6 3 false 0.0014436515044077298 0.0014436515044077298 1.5339974177634096E-21 gene_expression GO:0010467 12133 3708 36 30 6052 35 1 false 0.0015009889806100903 0.0015009889806100903 0.0 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 36 11 220 12 2 false 0.0015475839855713213 0.0015475839855713213 1.3850176335002185E-65 establishment_of_protein_localization GO:0045184 12133 1153 36 14 3010 19 2 false 0.0018356739253633449 0.0018356739253633449 0.0 protein_localization_to_organelle GO:0033365 12133 516 36 14 914 15 1 false 0.002222447116607902 0.002222447116607902 5.634955900168089E-271 negative_regulation_of_metabolic_process GO:0009892 12133 1354 36 13 8327 35 3 false 0.002286104271363444 0.002286104271363444 0.0 establishment_of_localization GO:0051234 12133 2833 36 18 10446 36 2 false 0.0028510285501721884 0.0028510285501721884 0.0 macromolecule_localization GO:0033036 12133 1642 36 16 3467 20 1 false 0.0029021339687446963 0.0029021339687446963 0.0 spliceosomal_complex GO:0005681 12133 150 36 6 3020 30 2 false 0.0029914835397441735 0.0029914835397441735 2.455159410572961E-258 regulation_of_ligase_activity GO:0051340 12133 98 36 3 2061 7 2 false 0.0031747963246885284 0.0031747963246885284 1.6310105681359867E-170 intracellular_receptor_signaling_pathway GO:0030522 12133 217 36 4 3547 11 1 false 0.003196006306856501 0.003196006306856501 0.0 nuclear_lumen GO:0031981 12133 2490 36 23 3186 23 2 false 0.003374740433526193 0.003374740433526193 0.0 positive_regulation_of_ligase_activity GO:0051351 12133 84 36 3 1424 6 3 false 0.003481788317791936 0.003481788317791936 5.130084211911676E-138 cellular_response_to_stress GO:0033554 12133 1124 36 8 4743 13 2 false 0.003910785087852269 0.003910785087852269 0.0 multi-organism_reproductive_process GO:0044703 12133 707 36 15 1275 17 1 false 0.004329387443304032 0.004329387443304032 0.0 regulation_of_cell_cycle GO:0051726 12133 659 36 7 6583 22 2 false 0.004343370777872983 0.004343370777872983 0.0 regulation_of_thymidylate_synthase_biosynthetic_process GO:0050758 12133 1 36 1 2834 13 2 false 0.004587155963315546 0.004587155963315546 3.5285815102348316E-4 localization GO:0051179 12133 3467 36 20 10446 36 1 false 0.004658597178526293 0.004658597178526293 0.0 negative_regulation_of_ligase_activity GO:0051352 12133 71 36 3 1003 6 3 false 0.005829461304746787 0.005829461304746787 8.698138776450475E-111 biosynthetic_process GO:0009058 12133 4179 36 26 8027 35 1 false 0.005988669879728377 0.005988669879728377 0.0 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 36 6 201 11 3 false 0.006069294883336619 0.006069294883336619 2.854176062301069E-41 cell_cycle GO:0007049 12133 1295 36 11 7541 29 1 false 0.006237654475287338 0.006237654475287338 0.0 small_molecule_binding GO:0036094 12133 2102 36 14 8962 31 1 false 0.006324781431087992 0.006324781431087992 0.0 RNA_helicase_activity GO:0003724 12133 27 36 3 140 3 1 false 0.006535144555163191 0.006535144555163191 1.8047202528374888E-29 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 36 3 759 4 3 false 0.006931424216224925 0.006931424216224925 1.1458874617943115E-123 thymidylate_synthase_biosynthetic_process GO:0050757 12133 1 36 1 3475 25 1 false 0.007194244604308485 0.007194244604308485 2.8776978417277126E-4 establishment_of_localization_in_cell GO:0051649 12133 1633 36 16 2978 19 2 false 0.007278729752548804 0.007278729752548804 0.0 RNA_splicing GO:0008380 12133 307 36 12 601 14 1 false 0.007482729215962212 0.007482729215962212 4.262015823312228E-180 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 36 12 7606 35 4 false 0.007956247042091425 0.007956247042091425 0.0 transcription_factor_binding GO:0008134 12133 715 36 7 6397 22 1 false 0.007995552980108275 0.007995552980108275 0.0 hormone_receptor_binding GO:0051427 12133 122 36 3 918 4 1 false 0.008292900146159653 0.008292900146159653 1.5301276126382055E-155 protein_localization_to_nuclear_pore GO:0090204 12133 1 36 1 233 2 1 false 0.00858369098712472 0.00858369098712472 0.004291845493562596 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 36 3 341 3 4 false 0.008725141628031483 0.008725141628031483 3.257446469032824E-75 phosphoprotein_binding GO:0051219 12133 42 36 2 6397 22 1 false 0.008945548085984203 0.008945548085984203 2.265958128878875E-109 negative_regulation_of_thymidylate_synthase_biosynthetic_process GO:0050760 12133 1 36 1 862 8 3 false 0.009280742459401085 0.009280742459401085 0.0011600928074245356 regulation_of_muscle_cell_differentiation GO:0051147 12133 103 36 3 987 5 2 false 0.009450063993803525 0.009450063993803525 9.48284116235963E-143 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 36 3 1813 7 1 false 0.009538887242421254 0.009538887242421254 4.219154160176784E-199 clathrin_coat_of_coated_pit GO:0030132 12133 14 36 1 1370 1 3 false 0.010218978102197114 0.010218978102197114 1.135698186932346E-33 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 36 3 362 3 4 false 0.010478362233003868 0.010478362233003868 1.827388630734988E-82 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 36 11 174 11 1 false 0.010803775125054572 0.010803775125054572 2.5039480990851377E-47 pore_complex GO:0046930 12133 84 36 2 5051 10 3 false 0.011278253470084413 0.011278253470084413 5.4712090537168384E-185 cytoplasmic_transport GO:0016482 12133 666 36 14 1148 16 1 false 0.011954379700675945 0.011954379700675945 0.0 ribose_phosphate_metabolic_process GO:0019693 12133 1207 36 8 3007 10 3 false 0.01247227404542734 0.01247227404542734 0.0 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 36 4 3020 30 2 false 0.012506540050458204 0.012506540050458204 1.1070924240418437E-179 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 36 3 2180 10 2 false 0.012762094088432995 0.012762094088432995 1.341003616993524E-193 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 36 2 3208 14 2 false 0.013161401402324701 0.013161401402324701 7.591030632914061E-95 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 36 3 1097 5 3 false 0.013302482653551231 0.013302482653551231 8.208279871491876E-172 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 36 3 389 3 3 false 0.0137691248402433 0.0137691248402433 8.074632425282073E-93 multi-organism_transport GO:0044766 12133 29 36 2 3441 22 2 false 0.014273723329415126 0.014273723329415126 2.716860412473803E-72 innate_immune_response GO:0045087 12133 626 36 6 1268 6 2 false 0.01430337245402851 0.01430337245402851 0.0 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 36 7 5778 15 3 false 0.014486805517534763 0.014486805517534763 0.0 positive_regulation_of_response_to_DNA_damage_stimulus GO:2001022 12133 44 36 2 3212 14 4 false 0.015035216266504996 0.015035216266504996 1.7987290458431554E-100 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 36 3 1056 8 3 false 0.015427611863714554 0.015427611863714554 4.764817151311381E-118 neurotrophin_signaling_pathway GO:0038179 12133 253 36 3 2018 5 2 false 0.01605201114393324 0.01605201114393324 0.0 nucleic_acid_binding GO:0003676 12133 2849 36 23 4407 27 2 false 0.016383266944229258 0.016383266944229258 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 36 26 7470 35 2 false 0.016619277941927108 0.016619277941927108 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 36 2 1199 7 2 false 0.0167475589973568 0.0167475589973568 9.194442294553035E-70 regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033143 12133 43 36 2 1642 8 2 false 0.016973995774272426 0.016973995774272426 5.767987369966462E-86 organic_substance_transport GO:0071702 12133 1580 36 15 2783 18 1 false 0.017128053562203153 0.017128053562203153 0.0 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 36 13 6103 35 3 false 0.01725553349754792 0.01725553349754792 0.0 basal_transcription_machinery_binding GO:0001098 12133 464 36 5 6397 22 1 false 0.018439239605483552 0.018439239605483552 0.0 nuclear_body GO:0016604 12133 272 36 5 805 6 1 false 0.01861349497147087 0.01861349497147087 8.12188174084084E-223 cellular_biosynthetic_process GO:0044249 12133 4077 36 26 7290 35 2 false 0.01966501906253261 0.01966501906253261 0.0 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 36 11 145 11 1 false 0.019715521087355678 0.019715521087355678 1.7288474062512548E-37 macromolecule_biosynthetic_process GO:0009059 12133 3475 36 25 6537 35 2 false 0.021264690838453747 0.021264690838453747 0.0 intracellular_transport_of_viral_material GO:0075733 12133 23 36 2 355 4 2 false 0.02228308391666308 0.02228308391666308 1.1844258992565298E-36 protein_transport GO:0015031 12133 1099 36 14 1627 15 2 false 0.022368688184574784 0.022368688184574784 0.0 release_from_viral_latency GO:0019046 12133 2 36 1 355 4 2 false 0.022439723084269936 0.022439723084269936 1.591469722288648E-5 RNA-dependent_ATPase_activity GO:0008186 12133 21 36 2 228 3 1 false 0.022980534256385278 0.022980534256385278 4.020483440001667E-30 response_to_stress GO:0006950 12133 2540 36 11 5200 14 1 false 0.023339257582578005 0.023339257582578005 0.0 pre-mRNA_binding GO:0036002 12133 10 36 2 763 19 1 false 0.02348548047747482 0.02348548047747482 5.757557985229243E-23 cell_cycle_process GO:0022402 12133 953 36 8 7541 29 2 false 0.023748462738723324 0.023748462738723324 0.0 negative_regulation_of_catalytic_activity GO:0043086 12133 588 36 5 4970 15 3 false 0.024860426044858178 0.024860426044858178 0.0 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 36 2 243 4 2 false 0.025499557374318044 0.025499557374318044 1.7559807727942103E-26 regulation_of_muscle_organ_development GO:0048634 12133 106 36 2 1105 3 2 false 0.025650159304767984 0.025650159304767984 5.2870889259577626E-151 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 36 1 6481 28 2 false 0.0256533461694638 0.0256533461694638 9.738359623180132E-21 protein_polyubiquitination GO:0000209 12133 163 36 3 548 3 1 false 0.025975742321702577 0.025975742321702577 3.681189236491621E-144 protein_binding_transcription_factor_activity GO:0000988 12133 488 36 5 10311 36 3 false 0.026106181810803767 0.026106181810803767 0.0 clathrin_coat_of_trans-Golgi_network_vesicle GO:0030130 12133 11 36 1 414 1 3 false 0.02657004830918312 0.02657004830918312 7.453188898335812E-22 negative_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043154 12133 63 36 2 1373 6 3 false 0.02759014719991914 0.02759014719991914 1.783777218833555E-110 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 36 4 912 4 2 false 0.02831627691340994 0.02831627691340994 2.059888800891414E-267 male_sex_determination GO:0030238 12133 13 36 1 3069 7 2 false 0.029305495432270835 0.029305495432270835 2.9810795844016348E-36 viral_reproductive_process GO:0022415 12133 557 36 15 783 16 2 false 0.030969753853430804 0.030969753853430804 1.4346997744229993E-203 receptor_signaling_protein_activity GO:0005057 12133 339 36 3 1070 3 1 false 0.03160920432211269 0.03160920432211269 2.5248591221043436E-289 regulation_of_protein_ubiquitination GO:0031396 12133 176 36 3 1344 6 2 false 0.03267694136171883 0.03267694136171883 8.0617715234352E-226 cellular_response_to_oxygen_levels GO:0071453 12133 85 36 2 1663 6 2 false 0.03386556827273519 0.03386556827273519 4.192529980934564E-145 negative_regulation_of_protein_modification_process GO:0031400 12133 328 36 4 2431 10 3 false 0.035085296763722865 0.035085296763722865 0.0 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 36 7 2556 9 1 false 0.0352728603292537 0.0352728603292537 0.0 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 36 25 6146 35 3 false 0.036168530357303 0.036168530357303 0.0 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 36 8 2807 10 3 false 0.036250597856463534 0.036250597856463534 0.0 intracellular_part GO:0044424 12133 9083 36 35 9983 35 2 false 0.03641811722155644 0.03641811722155644 0.0 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 36 2 2474 12 3 false 0.0367980818777107 0.0367980818777107 1.917782059478808E-128 protein_metabolic_process GO:0019538 12133 3431 36 22 7395 35 2 false 0.03690193331065817 0.03690193331065817 0.0 regulation_of_mRNA_processing GO:0050684 12133 49 36 2 3175 20 3 false 0.03714875756003501 0.03714875756003501 2.292701139367024E-109 response_to_DNA_damage_stimulus GO:0006974 12133 570 36 7 1124 8 1 false 0.03787131360694399 0.03787131360694399 0.0 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 36 3 202 8 1 false 0.038761575202324955 0.038761575202324955 5.801734415928739E-29 molecular_function GO:0003674 12133 10257 36 36 11221 36 1 false 0.03920124149380452 0.03920124149380452 0.0 pseudopodium GO:0031143 12133 13 36 1 976 3 1 false 0.03946906453027423 0.03946906453027423 9.253153669613935E-30 snRNA_modification GO:0040031 12133 3 36 1 76 1 2 false 0.03947368421052582 0.03947368421052582 1.4224751066856055E-5 trivalent_inorganic_cation_transport GO:0072512 12133 24 36 1 606 1 1 false 0.039603960396041464 0.039603960396041464 1.6359412389907096E-43 negative_regulation_of_molecular_function GO:0044092 12133 735 36 6 10257 36 2 false 0.040837769667790215 0.040837769667790215 0.0 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 36 4 1525 9 1 false 0.04096979650102955 0.04096979650102955 1.2095302863090285E-289 mRNA_catabolic_process GO:0006402 12133 181 36 11 592 22 2 false 0.041182142243274295 0.041182142243274295 1.4563864024176219E-157 muscle_cell_differentiation GO:0042692 12133 267 36 3 2218 7 2 false 0.04172025099291707 0.04172025099291707 0.0 ribonucleoprotein_complex_assembly GO:0022618 12133 117 36 3 646 5 3 false 0.0437857910114512 0.0437857910114512 4.631331466925404E-132 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 36 2 1014 4 1 false 0.0441855084518512 0.0441855084518512 2.468210871514413E-134 protein_export_from_nucleus GO:0006611 12133 46 36 2 2428 18 3 false 0.04432099978528963 0.04432099978528963 1.6048237175829586E-98 activation_of_MAPKK_activity GO:0000186 12133 64 36 2 496 3 3 false 0.045144668574232 0.045144668574232 2.7437381948522894E-82 proteasomal_protein_catabolic_process GO:0010498 12133 231 36 4 498 4 2 false 0.0456496590633516 0.0456496590633516 1.2543475178088858E-148 regulation_of_phosphorylation GO:0042325 12133 845 36 4 1820 4 2 false 0.04628986651905065 0.04628986651905065 0.0 negative_regulation_of_cysteine-type_endopeptidase_activity GO:2000117 12133 66 36 2 303 2 3 false 0.046882171660867056 0.046882171660867056 1.924144504065005E-68 positive_regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033148 12133 8 36 2 35 2 3 false 0.047058823529411764 0.047058823529411764 4.248842827655879E-8 apoptotic_signaling_pathway GO:0097190 12133 305 36 3 3954 11 2 false 0.04711302752378981 0.04711302752378981 0.0 immune_response GO:0006955 12133 1006 36 6 5335 15 2 false 0.04720398630134391 0.04720398630134391 0.0 signal_transduction_by_phosphorylation GO:0023014 12133 307 36 3 3947 11 2 false 0.048113943162391974 0.048113943162391974 0.0 negative_regulation_of_cellular_process GO:0048523 12133 2515 36 14 9689 35 3 false 0.04836043359701156 0.04836043359701156 0.0 response_to_hypoxia GO:0001666 12133 200 36 3 2540 11 2 false 0.04949155753126602 0.04949155753126602 2.6634431659671552E-303 negative_regulation_of_peptidase_activity GO:0010466 12133 156 36 2 695 2 3 false 0.05013165260301464 0.05013165260301464 5.1885244604442586E-160 skeletal_muscle_cell_differentiation GO:0035914 12133 57 36 2 251 2 2 false 0.05086852589641139 0.05086852589641139 6.638453930425573E-58 intracellular GO:0005622 12133 9171 36 35 9983 35 1 false 0.05106806915768965 0.05106806915768965 0.0 regulation_of_muscle_tissue_development GO:1901861 12133 105 36 2 1351 5 2 false 0.05123884058036678 0.05123884058036678 1.3105194568745759E-159 positive_regulation_of_signaling GO:0023056 12133 817 36 5 4861 13 3 false 0.052553911250472665 0.052553911250472665 0.0 telomeric_DNA_binding GO:0042162 12133 16 36 1 1189 4 1 false 0.05281529312941407 0.05281529312941407 1.4512187070438412E-36 helicase_activity GO:0004386 12133 140 36 3 1059 7 1 false 0.0529238813130928 0.0529238813130928 6.632628106941949E-179 single-organism_reproductive_behavior GO:0044704 12133 40 36 1 750 1 3 false 0.053333333333356096 0.053333333333356096 2.338867678628188E-67 antigen_processing_and_presentation GO:0019882 12133 185 36 3 1618 8 1 false 0.05334210072486607 0.05334210072486607 5.091289488805967E-249 regulation_of_protein_complex_assembly GO:0043254 12133 185 36 3 1610 8 3 false 0.05402062015066289 0.05402062015066289 1.34790682725651E-248 MAP_kinase_kinase_activity GO:0004708 12133 74 36 2 521 3 3 false 0.054286059319159315 0.054286059319159315 6.903948166738437E-92 positive_regulation_of_cell_communication GO:0010647 12133 820 36 5 4819 13 3 false 0.05504357554484491 0.05504357554484491 0.0 platelet_activation GO:0030168 12133 203 36 2 863 2 2 false 0.055122555806787016 0.055122555806787016 1.0918730712206789E-203 intracellular_organelle GO:0043229 12133 7958 36 34 9096 35 2 false 0.05550903748451406 0.05550903748451406 0.0 proline-rich_region_binding GO:0070064 12133 17 36 1 6397 22 1 false 0.05695300744047122 0.05695300744047122 7.222899753868919E-51 regulation_of_kinase_activity GO:0043549 12133 654 36 4 1335 4 3 false 0.05732552547320177 0.05732552547320177 0.0 histone_pre-mRNA_3'end_processing_complex GO:0071204 12133 6 36 1 3020 30 2 false 0.05818890422691216 0.05818890422691216 9.537822615543818E-19 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 36 24 5597 33 2 false 0.058870437860319993 0.058870437860319993 0.0 intracellular_organelle_lumen GO:0070013 12133 2919 36 23 5320 33 2 false 0.05993809685269802 0.05993809685269802 0.0 ligase_activity GO:0016874 12133 504 36 4 4901 15 1 false 0.060250667067543166 0.060250667067543166 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 36 24 5588 33 2 false 0.060884086262116666 0.060884086262116666 0.0 immune_response-regulating_signaling_pathway GO:0002764 12133 310 36 3 3626 11 2 false 0.06094922776894458 0.06094922776894458 0.0 organelle_lumen GO:0043233 12133 2968 36 23 5401 33 2 false 0.06110974594392141 0.06110974594392141 0.0 mRNA_splice_site_selection GO:0006376 12133 18 36 2 117 3 2 false 0.06136547111059822 0.06136547111059822 1.505085052005422E-21 sex_determination GO:0007530 12133 21 36 1 340 1 1 false 0.0617647058823462 0.0617647058823462 6.623492102010024E-34 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 36 24 5686 33 2 false 0.06213363198550888 0.06213363198550888 0.0 anion_binding GO:0043168 12133 2280 36 8 4448 10 1 false 0.06389858055417076 0.06389858055417076 0.0 regulation_of_skeletal_muscle_cell_differentiation GO:2001014 12133 27 36 2 105 2 3 false 0.06428571428571116 0.06428571428571116 1.1402717682449654E-25 negative_regulation_of_biological_process GO:0048519 12133 2732 36 14 10446 36 2 false 0.06432661115951815 0.06432661115951815 0.0 regulation_of_response_to_stress GO:0080134 12133 674 36 5 3466 12 2 false 0.06508847479490809 0.06508847479490809 0.0 positive_regulation_of_signal_transduction GO:0009967 12133 782 36 5 3650 11 5 false 0.06517000451833202 0.06517000451833202 0.0 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 36 24 5629 33 2 false 0.06524131813824621 0.06524131813824621 0.0 mRNA_3'-splice_site_recognition GO:0000389 12133 5 36 2 18 2 1 false 0.06535947712418336 0.06535947712418336 1.1671335200746984E-4 mitogen-activated_protein_kinase_kinase_binding GO:0031434 12133 12 36 1 341 2 1 false 0.06924271174744936 0.06924271174744936 2.356690583847287E-22 visual_behavior GO:0007632 12133 33 36 1 4138 9 3 false 0.06959151865247576 0.06959151865247576 4.36677022039695E-83 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 36 2 2025 5 2 false 0.07105881184164738 0.07105881184164738 5.184659787643375E-271 Leydig_cell_differentiation GO:0033327 12133 10 36 1 2446 18 4 false 0.07132680666774163 0.07132680666774163 4.821684083574537E-28 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 36 3 856 4 3 false 0.07236948579893135 0.07236948579893135 2.175375701359491E-221 positive_regulation_of_cell_cycle GO:0045787 12133 98 36 2 3492 16 3 false 0.07248030770703781 0.07248030770703781 2.23767062140918E-193 positive_regulation_of_signal_transduction_by_p53_class_mediator GO:1901798 12133 11 36 1 881 6 3 false 0.07281546300003555 0.07281546300003555 1.712543759931694E-25 organic_substance_metabolic_process GO:0071704 12133 7451 36 35 8027 35 1 false 0.07339212775241821 0.07339212775241821 0.0 response_to_growth_factor_stimulus GO:0070848 12133 545 36 4 1783 6 1 false 0.07471649993647901 0.07471649993647901 0.0 pigment_granule GO:0048770 12133 87 36 2 712 4 1 false 0.07515232378481648 0.07515232378481648 3.4546414966613156E-114 biological_process GO:0008150 12133 10446 36 36 11221 36 1 false 0.07572713654258807 0.07572713654258807 0.0 regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900739 12133 24 36 1 315 1 3 false 0.07619047619048347 0.07619047619048347 1.6734366655590734E-36 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 36 3 587 3 2 false 0.07764643021720977 0.07764643021720977 2.854325455984618E-173 ATP-dependent_helicase_activity GO:0008026 12133 98 36 3 228 3 2 false 0.07801891380043076 0.07801891380043076 4.1384935546953996E-67 cellular_protein_complex_localization GO:0034629 12133 5 36 1 930 15 2 false 0.07824835138649298 0.07824835138649298 1.7435880605018067E-13 protein_kinase_C_inhibitor_activity GO:0008426 12133 3 36 1 38 1 2 false 0.0789473684210529 0.0789473684210529 1.1853959222380309E-4 regulation_of_protein_kinase_activity GO:0045859 12133 621 36 4 1169 4 3 false 0.07927489096661264 0.07927489096661264 0.0 trans-Golgi_network_transport_vesicle_membrane GO:0012510 12133 12 36 1 151 1 4 false 0.07947019867549363 0.07947019867549363 5.3388603233551054E-18 regulation_of_RNA_stability GO:0043487 12133 37 36 1 2240 5 2 false 0.0799746643536866 0.0799746643536866 2.0388833014238124E-81 negative_regulation_of_DNA_binding GO:0043392 12133 35 36 1 2119 5 3 false 0.07997565526897901 0.07997565526897901 5.275494739019896E-77 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 36 4 742 4 2 false 0.0813730770489196 0.0813730770489196 9.121396596563632E-222 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 36 9 5447 34 3 false 0.08158732432515403 0.08158732432515403 0.0 proteasome_accessory_complex GO:0022624 12133 23 36 1 9248 35 3 false 0.08361168583257376 0.08361168583257376 1.6042989552874397E-69 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 36 2 1881 7 2 false 0.08460748149035142 0.08460748149035142 3.367676499542027E-210 regulation_of_response_to_stimulus GO:0048583 12133 2074 36 9 7292 20 2 false 0.08507686182204807 0.08507686182204807 0.0 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 36 8 374 10 2 false 0.08608400871718667 0.08608400871718667 2.0954491420584897E-111 cell_part GO:0044464 12133 9983 36 35 10701 35 2 false 0.08760806904019375 0.08760806904019375 0.0 cell GO:0005623 12133 9984 36 35 10701 35 1 false 0.08791626910248015 0.08791626910248015 0.0 chromatin_binding GO:0003682 12133 309 36 3 8962 31 1 false 0.08981088181919804 0.08981088181919804 0.0 trans-Golgi_network_transport_vesicle GO:0030140 12133 23 36 1 256 1 3 false 0.08984374999999867 0.08984374999999867 2.9196979468044646E-33 positive_regulation_of_protein_modification_process GO:0031401 12133 708 36 5 2417 9 3 false 0.08997550202737441 0.08997550202737441 0.0 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 36 4 1975 5 1 false 0.09191503631023853 0.09191503631023853 0.0 regulation_of_skeletal_muscle_tissue_development GO:0048641 12133 63 36 2 206 2 2 false 0.0924934880416732 0.0924934880416732 1.364605297408496E-54 regulation_of_mitochondrial_outer_membrane_permeabilization GO:1901028 12133 33 36 1 354 1 4 false 0.09322033898306151 0.09322033898306151 3.0911895026883726E-47 vesicle_membrane GO:0012506 12133 312 36 3 9991 35 4 false 0.09492444368525968 0.09492444368525968 0.0 trans-Golgi_network_membrane GO:0032588 12133 26 36 1 9083 35 3 false 0.09563239551036715 0.09563239551036715 5.095783492585907E-77 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 36 2 86 2 2 false 0.09603283173734763 0.09603283173734763 6.233113581740502E-23 response_to_oxygen_levels GO:0070482 12133 214 36 3 676 4 1 false 0.09613026838216968 0.09613026838216968 1.6255941364061853E-182 nuclear_body_organization GO:0030575 12133 6 36 1 62 1 1 false 0.09677419354838807 0.09677419354838807 1.626690238926508E-8 cytoplasmic_part GO:0044444 12133 5117 36 24 9083 35 2 false 0.09703523363471978 0.09703523363471978 0.0 response_to_abiotic_stimulus GO:0009628 12133 676 36 4 5200 14 1 false 0.0976601881216349 0.0976601881216349 0.0 cellular_response_to_organic_substance GO:0071310 12133 1347 36 6 1979 6 2 false 0.099079269937087 0.099079269937087 0.0 negative_regulation_of_cell_cycle GO:0045786 12133 298 36 4 3131 19 3 false 0.09949036184563147 0.09949036184563147 0.0 virion_assembly GO:0019068 12133 11 36 1 2070 20 4 false 0.10152559507961932 0.10152559507961932 1.3710102562261885E-29 keratinocyte_proliferation GO:0043616 12133 23 36 1 225 1 1 false 0.10222222222222503 0.10222222222222503 6.573252353686376E-32 negative_regulation_of_endopeptidase_activity GO:0010951 12133 152 36 2 474 2 3 false 0.10237196813588902 0.10237196813588902 1.8080345918982332E-128 regulation_of_mitochondrial_membrane_permeability GO:0046902 12133 46 36 1 2152 5 3 false 0.10249607389137046 0.10249607389137046 4.367031159968052E-96 muscle_structure_development GO:0061061 12133 413 36 3 3152 9 2 false 0.10255106546560332 0.10255106546560332 0.0 protein_kinase_C_activity GO:0004697 12133 19 36 1 709 4 1 false 0.10317051060648307 0.10317051060648307 1.067786620182717E-37 SUMO_ligase_activity GO:0019789 12133 9 36 1 335 4 1 false 0.10365561445527008 0.10365561445527008 7.610794818623194E-18 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 36 3 6813 24 2 false 0.10471750091743093 0.10471750091743093 0.0 cell_growth GO:0016049 12133 299 36 3 7559 29 2 false 0.105226856924001 0.105226856924001 0.0 taxis GO:0042330 12133 488 36 2 1496 2 2 false 0.10626151342276739 0.10626151342276739 0.0 paraspeckles GO:0042382 12133 6 36 1 272 5 1 false 0.10628418301342021 0.10628418301342021 1.8794561691225117E-12 negative_regulation_of_ERBB_signaling_pathway GO:1901185 12133 39 36 1 705 2 3 false 0.10765232108317874 0.10765232108317874 4.9570646354646075E-65 regulation_of_transferase_activity GO:0051338 12133 667 36 4 2708 8 2 false 0.10844796325821897 0.10844796325821897 0.0 regulation_of_signal_transduction_by_p53_class_mediator GO:1901796 12133 24 36 1 1685 8 2 false 0.10863981896227812 0.10863981896227812 2.665493557536061E-54 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 36 5 1541 9 3 false 0.10941996534673609 0.10941996534673609 0.0 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 36 4 381 4 2 false 0.10988627231670786 0.10988627231670786 4.820433761728018E-112 nuclear_pore GO:0005643 12133 69 36 2 2781 23 3 false 0.10994624635749933 0.10994624635749933 8.971129873692015E-140 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 36 9 5032 34 4 false 0.11143816451224914 0.11143816451224914 0.0 positive_regulation_of_mitochondrion_organization GO:0010822 12133 43 36 1 385 1 3 false 0.11168831168830058 0.11168831168830058 4.6200993055738E-58 cellular_response_to_hypoxia GO:0071456 12133 79 36 2 1210 9 3 false 0.11241950599078283 0.11241950599078283 3.484581288071841E-126 protein_acylation GO:0043543 12133 155 36 2 2370 9 1 false 0.11303382483808272 0.11303382483808272 6.767829300235778E-248 snRNA_metabolic_process GO:0016073 12133 15 36 1 258 2 1 false 0.1131119355714382 0.1131119355714382 1.3254371174076553E-24 regulation_of_cell_differentiation GO:0045595 12133 872 36 5 6612 20 3 false 0.11315578258264747 0.11315578258264747 0.0 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 36 2 1130 4 2 false 0.11325728054531922 0.11325728054531922 2.620015602340521E-209 nucleoside_metabolic_process GO:0009116 12133 1083 36 7 2072 9 4 false 0.11374318463592474 0.11374318463592474 0.0 coated_membrane GO:0048475 12133 66 36 1 4398 8 1 false 0.11402062923121394 0.11402062923121394 3.1181974111959693E-148 cellular_response_to_interferon-gamma GO:0071346 12133 83 36 2 392 3 2 false 0.11476911834968431 0.11476911834968431 2.629901965674187E-87 U2-type_spliceosomal_complex GO:0005684 12133 3 36 1 150 6 1 false 0.11600943225105198 0.11600943225105198 1.813894431344149E-6 protein_serine/threonine_kinase_inhibitor_activity GO:0030291 12133 22 36 1 724 4 3 false 0.11634849782755796 0.11634849782755796 1.8900653580041414E-42 Notch_receptor_processing GO:0007220 12133 17 36 1 3038 22 1 false 0.11651675751016011 0.11651675751016011 2.325698863690895E-45 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 36 5 200 11 3 false 0.11656561928451473 0.11656561928451473 7.491323649368413E-49 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 36 3 417 3 4 false 0.11792410371980254 0.11792410371980254 8.022991700655629E-125 beta-amyloid_binding GO:0001540 12133 21 36 1 178 1 1 false 0.11797752808989305 0.11797752808989305 9.611254331896559E-28 viral_latency GO:0019042 12133 11 36 1 355 4 1 false 0.11878057126548176 0.11878057126548176 4.136206699450328E-21 cellular_protein_metabolic_process GO:0044267 12133 3038 36 22 5899 35 2 false 0.11891550586552946 0.11891550586552946 0.0 positive_regulation_of_protein_binding GO:0032092 12133 37 36 1 6397 22 3 false 0.11999449835731804 0.11999449835731804 2.3062856812384995E-98 calcium-dependent_protein_binding GO:0048306 12133 37 36 1 6397 22 1 false 0.11999449835731804 0.11999449835731804 2.3062856812384995E-98 ephrin_receptor_binding GO:0046875 12133 29 36 1 918 4 1 false 0.1206870203887151 0.1206870203887151 1.6526990639165767E-55 regulation_of_binding GO:0051098 12133 172 36 2 9142 32 2 false 0.12106887689006554 0.12106887689006554 0.0 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 36 2 1130 4 2 false 0.12152712975945293 0.12152712975945293 1.9819409219356823E-214 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 36 3 639 3 3 false 0.12266269311991101 0.12266269311991101 1.399157780258238E-191 regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033146 12133 20 36 2 56 2 2 false 0.12337662337662375 0.12337662337662375 1.2728904491493287E-15 SH2_domain_binding GO:0042169 12133 31 36 1 486 2 1 false 0.12362649017858361 0.12362649017858361 1.1318841086292139E-49 regulation_of_signal_transduction GO:0009966 12133 1603 36 7 3826 11 4 false 0.12414922611960291 0.12414922611960291 0.0 regulation_of_protein_catabolic_process GO:0042176 12133 150 36 2 1912 8 3 false 0.1252547639084536 0.1252547639084536 1.3832082048306078E-227 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 36 3 506 4 3 false 0.12539200155645489 0.12539200155645489 1.5079927652081954E-141 response_to_peptide GO:1901652 12133 322 36 2 904 2 2 false 0.1266207038486307 0.1266207038486307 7.8711156655671515E-255 neuron_migration GO:0001764 12133 89 36 1 1360 2 2 false 0.12664480803366832 0.12664480803366832 4.085890514650152E-142 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 36 2 953 8 3 false 0.12844085036455616 0.12844085036455616 1.5807807987211998E-114 response_to_interferon-gamma GO:0034341 12133 97 36 2 900 6 2 false 0.12936473047483457 0.12936473047483457 5.665951698458868E-133 histone_H4_acetylation GO:0043967 12133 44 36 2 121 2 1 false 0.1303030303030334 0.1303030303030334 4.76799917217802E-34 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 36 3 415 4 3 false 0.13179441334607428 0.13179441334607428 9.462933237946419E-117 transition_metal_ion_transport GO:0000041 12133 60 36 1 455 1 1 false 0.13186813186813184 0.13186813186813184 1.613674695371724E-76 RNA_methylation GO:0001510 12133 25 36 1 188 1 2 false 0.13297872340425027 0.13297872340425027 1.1533363650630908E-31 MLL5-L_complex GO:0070688 12133 8 36 1 60 1 1 false 0.13333333333333472 0.13333333333333472 3.9083555578552816E-10 regulation_of_striated_muscle_tissue_development GO:0016202 12133 105 36 2 286 2 3 false 0.13397129186601853 0.13397129186601853 4.516187028693684E-81 microtubule_cytoskeleton GO:0015630 12133 734 36 3 1430 3 1 false 0.13496297470255245 0.13496297470255245 0.0 kinase_inhibitor_activity GO:0019210 12133 49 36 1 1377 4 4 false 0.13505877866273336 0.13505877866273336 2.2473743885530668E-91 negative_regulation_of_neuron_differentiation GO:0045665 12133 49 36 1 1036 3 3 false 0.13541110280237556 0.13541110280237556 3.406732198997762E-85 positive_regulation_of_metabolic_process GO:0009893 12133 1872 36 11 8366 35 3 false 0.1398463591759852 0.1398463591759852 0.0 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 36 3 220 4 1 false 0.14239945656794112 0.14239945656794112 2.4407604211478482E-62 MAP_kinase_kinase_kinase_activity GO:0004709 12133 26 36 1 520 3 3 false 0.1428861561808948 0.1428861561808948 1.8429565665115438E-44 immune_response-regulating_cell_surface_receptor_signaling_pathway_involved_in_phagocytosis GO:0002433 12133 72 36 1 500 1 2 false 0.1440000000000127 0.1440000000000127 6.2427882790248544E-89 regulation_of_peptidase_activity GO:0052547 12133 276 36 2 1151 3 2 false 0.14467610183444343 0.14467610183444343 1.6233323078676786E-274 ribosome_assembly GO:0042255 12133 16 36 1 417 4 3 false 0.14536139150895494 0.14536139150895494 3.349634512578164E-29 organelle_organization GO:0006996 12133 2031 36 11 7663 30 2 false 0.14574969315600542 0.14574969315600542 0.0 ephrin_receptor_signaling_pathway GO:0048013 12133 30 36 1 586 3 1 false 0.14609174857432877 0.14609174857432877 5.184030943639595E-51 nucleoplasm GO:0005654 12133 1443 36 15 2767 23 2 false 0.14671118689992618 0.14671118689992618 0.0 positive_regulation_of_kinase_activity GO:0033674 12133 438 36 3 1181 4 3 false 0.14690046477455157 0.14690046477455157 0.0 Golgi-associated_vesicle_membrane GO:0030660 12133 29 36 1 553 3 3 false 0.14947384973168737 0.14947384973168737 5.3948858906392845E-49 regulation_of_protein_modification_process GO:0031399 12133 1001 36 6 2566 10 2 false 0.1497084350213749 0.1497084350213749 0.0 insulin_receptor_signaling_pathway GO:0008286 12133 151 36 2 617 3 2 false 0.14990548645722845 0.14990548645722845 2.0667953594506098E-148 Set1C/COMPASS_complex GO:0048188 12133 9 36 1 60 1 1 false 0.1500000000000016 0.1500000000000016 6.764461542441828E-11 MAP_kinase_activity GO:0004707 12133 277 36 3 520 3 2 false 0.15039073565077132 0.15039073565077132 2.5282679507054518E-155 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 36 3 1112 4 4 false 0.15119555481507585 0.15119555481507585 1.302733E-318 positive_regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902110 12133 37 36 1 1374 6 3 false 0.15133462516339447 0.15133462516339447 1.7604614397711276E-73 regulation_of_immune_response GO:0050776 12133 533 36 4 2461 10 3 false 0.1514305331796092 0.1514305331796092 0.0 histone_acetylation GO:0016573 12133 121 36 2 309 2 2 false 0.15256588072118815 0.15256588072118815 3.1224257129978892E-89 primary_metabolic_process GO:0044238 12133 7288 36 34 8027 35 1 false 0.1542247527424654 0.1542247527424654 0.0 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 36 2 1376 6 3 false 0.15512514231966315 0.15512514231966315 2.059495184181185E-218 positive_regulation_of_phosphorylation GO:0042327 12133 563 36 3 1487 4 3 false 0.15513831081328724 0.15513831081328724 0.0 cellular_response_to_peptide GO:1901653 12133 247 36 2 625 2 3 false 0.15580000000000666 0.15580000000000666 2.2359681686760748E-181 GTP_binding GO:0005525 12133 292 36 3 1635 8 3 false 0.15752993162688167 0.15752993162688167 0.0 regulation_of_cell_cycle_arrest GO:0071156 12133 89 36 2 481 4 2 false 0.15756969703691848 0.15756969703691848 1.91357850692127E-99 regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902108 12133 39 36 1 1375 6 3 false 0.1588297940085601 0.1588297940085601 1.4191902379759833E-76 regulation_of_Rac_protein_signal_transduction GO:0035020 12133 23 36 1 278 2 2 false 0.15889670934732794 0.15889670934732794 4.034778444759645E-34 rRNA_binding GO:0019843 12133 29 36 2 763 19 1 false 0.160129400379091 0.160129400379091 3.8668021308986908E-53 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 36 5 3605 25 4 false 0.16037211565712328 0.16037211565712328 0.0 coated_pit GO:0005905 12133 52 36 1 10213 35 3 false 0.1638592218429608 0.1638592218429608 3.070128605674566E-141 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 36 1 1977 9 3 false 0.16446562104923587 0.16446562104923587 8.49513097758148E-83 palate_development GO:0060021 12133 62 36 1 3099 9 1 false 0.16649970780020323 0.16649970780020323 2.0367343521071395E-131 nucleolus GO:0005730 12133 1357 36 13 4208 31 3 false 0.16667204611630482 0.16667204611630482 0.0 activation_of_MAPK_activity GO:0000187 12133 158 36 3 286 3 2 false 0.1671675988948046 0.1671675988948046 8.207976102051858E-85 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 36 2 599 3 2 false 0.16768534550515468 0.16768534550515468 1.7219296535416308E-148 muscle_tissue_development GO:0060537 12133 295 36 2 1132 3 1 false 0.1680969681448254 0.1680969681448254 3.412889797328503E-281 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 36 4 1356 6 2 false 0.16825406832426326 0.16825406832426326 0.0 regulation_of_response_to_DNA_damage_stimulus GO:2001020 12133 80 36 2 741 7 2 false 0.1691572760837359 0.1691572760837359 1.553661553762129E-109 protein_kinase_inhibitor_activity GO:0004860 12133 46 36 1 1016 4 4 false 0.16940331750179718 0.16940331750179718 7.458157078887417E-81 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 36 5 5051 15 3 false 0.1705288080154276 0.1705288080154276 0.0 cysteine-type_endopeptidase_activity GO:0004197 12133 219 36 2 527 2 2 false 0.17222819460181882 0.17222819460181882 1.229090165658057E-154 regulation_of_DNA_binding GO:0051101 12133 67 36 1 2162 6 2 false 0.17229896803194256 0.17229896803194256 3.7616659824415835E-129 clathrin_vesicle_coat GO:0030125 12133 20 36 1 116 1 3 false 0.1724137931034499 0.1724137931034499 7.110456703810784E-23 Rac_protein_signal_transduction GO:0016601 12133 33 36 1 365 2 1 false 0.17287370164083218 0.17287370164083218 1.0734561739608448E-47 cytoplasmic_microtubule GO:0005881 12133 41 36 1 5210 24 2 false 0.17307071458769363 0.17307071458769363 1.5944596258703277E-103 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 36 2 3297 16 3 false 0.17339485490690562 0.17339485490690562 4.623981712175632E-272 negative_regulation_of_mRNA_processing GO:0050686 12133 13 36 1 1096 16 3 false 0.17489316259894347 0.17489316259894347 2.031276795679201E-30 ribosomal_small_subunit_assembly GO:0000028 12133 6 36 1 128 4 3 false 0.1766601049868752 0.1766601049868752 1.8437899825856603E-10 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 36 3 750 4 3 false 0.17705080906386056 0.17705080906386056 3.090255244762607E-218 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 36 2 1379 2 2 false 0.17917108272464566 0.17917108272464566 0.0 regulation_of_cellular_component_organization GO:0051128 12133 1152 36 7 7336 30 2 false 0.180548198344074 0.180548198344074 0.0 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 36 2 859 4 3 false 0.18079895553473124 0.18079895553473124 4.662302019201105E-186 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 36 2 278 3 3 false 0.1823686240146435 0.1823686240146435 2.8121052478162137E-70 RNA_methyltransferase_activity GO:0008173 12133 23 36 1 126 1 2 false 0.1825396825396866 0.1825396825396866 1.0792211566104033E-25 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 36 5 3910 25 3 false 0.18255237968646032 0.18255237968646032 0.0 response_to_cytokine_stimulus GO:0034097 12133 461 36 3 1783 6 1 false 0.18286753394274663 0.18286753394274663 0.0 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 36 9 3631 31 4 false 0.1835728208140394 0.1835728208140394 0.0 immune_system_process GO:0002376 12133 1618 36 8 10446 36 1 false 0.18373412669573325 0.18373412669573325 0.0 establishment_of_RNA_localization GO:0051236 12133 124 36 2 2839 18 2 false 0.1841478867285743 0.1841478867285743 1.4765023034812589E-220 endocytic_vesicle_membrane GO:0030666 12133 97 36 2 352 3 2 false 0.18519258519262305 0.18519258519262305 2.1109282121886535E-89 regulation_of_innate_immune_response GO:0045088 12133 226 36 3 868 6 3 false 0.18550558121572458 0.18550558121572458 2.196344369914344E-215 regulation_of_steroid_metabolic_process GO:0019218 12133 56 36 1 301 1 2 false 0.18604651162788827 0.18604651162788827 2.659882776337694E-62 post-embryonic_development GO:0009791 12133 81 36 1 4373 11 3 false 0.18608445306499524 0.18608445306499524 1.5270071764931075E-174 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 36 3 2943 18 3 false 0.18608463238335077 0.18608463238335077 0.0 outer_membrane GO:0019867 12133 112 36 1 4398 8 1 false 0.18660181759216263 0.18660181759216263 7.412183245910406E-226 positive_regulation_of_cellular_process GO:0048522 12133 2811 36 13 9694 35 3 false 0.18847058858483556 0.18847058858483556 0.0 regulation_of_interferon-gamma-mediated_signaling_pathway GO:0060334 12133 22 36 1 114 1 3 false 0.1929824561403555 0.1929824561403555 5.496543393824805E-24 positive_regulation_of_transferase_activity GO:0051347 12133 445 36 3 2275 8 3 false 0.19318319936271638 0.19318319936271638 0.0 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 36 2 859 4 3 false 0.193462696371892 0.193462696371892 3.480270935062193E-190 type_I_interferon_production GO:0032606 12133 71 36 1 362 1 1 false 0.19613259668509953 0.19613259668509953 2.8677775679244762E-77 positive_regulation_of_protein_export_from_nucleus GO:0046827 12133 13 36 1 126 2 4 false 0.1964444444444454 0.1964444444444454 5.8569430780046546E-18 Golgi-associated_vesicle GO:0005798 12133 52 36 1 975 4 2 false 0.1971444723127547 0.1971444723127547 1.201522273090165E-87 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 36 19 8688 35 3 false 0.19835359340746367 0.19835359340746367 0.0 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 36 24 4989 33 5 false 0.19923684742714406 0.19923684742714406 0.0 regulation_of_cellular_response_to_stress GO:0080135 12133 270 36 2 6503 20 3 false 0.20066790818798402 0.20066790818798402 0.0 endocytic_vesicle GO:0030139 12133 152 36 2 712 4 1 false 0.201443257524391 0.201443257524391 1.2528026489004738E-159 cytoplasmic_vesicle_membrane GO:0030659 12133 302 36 3 719 4 3 false 0.20240141324446811 0.20240141324446811 1.2351303462379864E-211 epidermal_cell_differentiation GO:0009913 12133 101 36 1 499 1 2 false 0.20240480961921403 0.20240480961921403 1.5497719224062011E-108 regulation_of_protein_stability GO:0031647 12133 99 36 1 2240 5 2 false 0.20245816936575836 0.20245816936575836 1.7785498552391114E-175 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 36 1 201 1 3 false 0.20398009950248341 0.20398009950248341 9.949481941404742E-44 extracellular_membrane-bounded_organelle GO:0065010 12133 59 36 1 7284 28 2 false 0.20399262647866345 0.20399262647866345 2.3146567535480854E-148 protein_sumoylation GO:0016925 12133 32 36 1 578 4 1 false 0.20421839747886023 0.20421839747886023 2.618927943730716E-53 skin_development GO:0043588 12133 45 36 1 219 1 1 false 0.2054794520548016 0.2054794520548016 7.404008409321376E-48 regulation_of_type_I_interferon_production GO:0032479 12133 67 36 1 325 1 2 false 0.2061538461538324 0.2061538461538324 2.788484219003069E-71 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 36 3 1398 6 2 false 0.20622759486424078 0.20622759486424078 0.0 activation_of_protein_kinase_activity GO:0032147 12133 247 36 3 417 3 1 false 0.20678577619830135 0.20678577619830135 9.475379918718814E-122 steroid_hormone_receptor_binding GO:0035258 12133 62 36 3 104 3 1 false 0.20768352150417926 0.20768352150417926 4.2931773052216616E-30 cell_cycle_arrest GO:0007050 12133 202 36 3 998 8 2 false 0.20774767616874856 0.20774767616874856 1.5077994882682823E-217 negative_regulation_of_muscle_cell_differentiation GO:0051148 12133 33 36 1 584 4 3 false 0.2080702241263003 0.2080702241263003 1.1148204606376211E-54 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 36 4 2370 9 1 false 0.20910329803496702 0.20910329803496702 0.0 proteasome_complex GO:0000502 12133 62 36 1 9248 35 2 false 0.21011723413069658 0.21011723413069658 4.919625587422917E-161 methyltransferase_complex GO:0034708 12133 62 36 1 9248 35 2 false 0.21011723413069658 0.21011723413069658 4.919625587422917E-161 endocytosis GO:0006897 12133 411 36 2 895 2 2 false 0.2106032769674332 0.2106032769674332 2.7872223899360555E-267 peptidyl-lysine_modification GO:0018205 12133 185 36 2 623 3 1 false 0.21175872832364373 0.21175872832364373 7.634244791194444E-164 regulation_of_striated_muscle_cell_differentiation GO:0051153 12133 68 36 2 227 3 2 false 0.21432198874639413 0.21432198874639413 1.1311225924750782E-59 extracellular_organelle GO:0043230 12133 59 36 1 8358 34 2 false 0.2144248657459242 0.2144248657459242 6.7158083402639515E-152 clathrin-coated_endocytic_vesicle GO:0045334 12133 31 36 1 272 2 2 false 0.2153245061862137 0.2153245061862137 1.6415618681542047E-41 negative_regulation_of_cytokine_production GO:0001818 12133 114 36 1 529 1 3 false 0.21550094517957671 0.21550094517957671 4.407958658606205E-119 male_sex_differentiation GO:0046661 12133 105 36 1 3074 7 2 false 0.21613862444851292 0.21613862444851292 4.0305150218166505E-198 negative_regulation_of_type_I_interferon_production GO:0032480 12133 32 36 1 148 1 3 false 0.21621621621620796 0.21621621621620796 3.492638478654734E-33 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 36 1 695 2 3 false 0.21711276511940794 0.21711276511940794 3.5521820546065696E-107 protein_insertion_into_mitochondrial_membrane GO:0051204 12133 25 36 1 1644 16 4 false 0.2183219060721919 0.2183219060721919 7.460154269678152E-56 membrane_coat GO:0030117 12133 66 36 1 7525 28 4 false 0.21894543773852027 0.21894543773852027 1.024710613883824E-163 positive_regulation_of_peptidyl-serine_phosphorylation GO:0033138 12133 47 36 1 594 3 3 false 0.21942681797238892 0.21942681797238892 7.186758669481106E-71 Ada2/Gcn5/Ada3_transcription_activator_complex GO:0005671 12133 16 36 1 72 1 1 false 0.2222222222222221 0.2222222222222221 2.4293632143762976E-16 regulation_of_cellular_amino_acid_metabolic_process GO:0006521 12133 55 36 1 4147 19 4 false 0.22448753590863676 0.22448753590863676 1.925356420452305E-126 regulation_of_cell_death GO:0010941 12133 1062 36 5 6437 20 2 false 0.22449139053647726 0.22449139053647726 0.0 growth_cone GO:0030426 12133 85 36 1 711 2 3 false 0.22495592401106182 0.22495592401106182 2.0579726954820752E-112 regulation_of_immune_system_process GO:0002682 12133 794 36 4 6789 21 2 false 0.22512467669088226 0.22512467669088226 0.0 negative_regulation_of_binding GO:0051100 12133 72 36 1 9054 32 3 false 0.22580425903222395 0.22580425903222395 1.0408990583833388E-181 activation_of_immune_response GO:0002253 12133 341 36 3 1618 8 2 false 0.22684789478028267 0.22684789478028267 0.0 protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:0001844 12133 25 36 1 305 3 3 false 0.226979557317243 0.226979557317243 3.3284741778861134E-37 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 36 1 22 1 1 false 0.22727272727272646 0.22727272727272646 3.79737221842484E-5 termination_of_RNA_polymerase_II_transcription GO:0006369 12133 44 36 1 1385 8 2 false 0.22813225670139003 0.22813225670139003 3.166663017097352E-84 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 36 3 217 3 2 false 0.22821538718009737 0.22821538718009737 2.2668758893633536E-62 protein_complex_subunit_organization GO:0071822 12133 989 36 16 1256 18 1 false 0.22839327389656788 0.22839327389656788 2.2763776011987297E-281 regulation_of_MAPK_cascade GO:0043408 12133 429 36 3 701 3 2 false 0.22857867056859496 0.22857867056859496 1.5434745144062482E-202 positive_regulation_of_binding GO:0051099 12133 73 36 1 9050 32 3 false 0.22865145954495672 0.22865145954495672 8.738239425278628E-184 regulation_of_ERBB_signaling_pathway GO:1901184 12133 61 36 1 1663 7 2 false 0.23054636016567492 0.23054636016567492 5.186655572840897E-113 glycosyl_compound_metabolic_process GO:1901657 12133 1093 36 7 7599 35 2 false 0.2306660230165524 0.2306660230165524 0.0 cardiovascular_system_development GO:0072358 12133 655 36 3 2686 7 2 false 0.23073855854789288 0.23073855854789288 0.0 circulatory_system_development GO:0072359 12133 655 36 3 2686 7 1 false 0.23073855854789288 0.23073855854789288 0.0 axon_guidance GO:0007411 12133 295 36 2 611 2 2 false 0.2327010276087109 0.2327010276087109 5.229199602535248E-183 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 36 3 541 4 2 false 0.2346513220949496 0.2346513220949496 1.01164377942614E-160 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 36 4 673 5 2 false 0.2353973193320656 0.2353973193320656 4.9348138289436974E-201 H4_histone_acetyltransferase_activity GO:0010485 12133 10 36 1 80 2 2 false 0.23575949367088528 0.23575949367088528 6.073518323310398E-13 Rho_protein_signal_transduction GO:0007266 12133 178 36 2 365 2 1 false 0.23713683576697228 0.23713683576697228 3.561371803691081E-109 regulation_of_viral_genome_replication GO:0045069 12133 43 36 1 181 1 3 false 0.23756906077349124 0.23756906077349124 1.1493804978494703E-42 protein_serine/threonine_kinase_activity GO:0004674 12133 709 36 4 1014 4 1 false 0.23841003926873663 0.23841003926873663 1.8231541307779663E-268 muscle_organ_development GO:0007517 12133 308 36 2 1966 6 2 false 0.23913337714072172 0.23913337714072172 0.0 regulation_of_protein_export_from_nucleus GO:0046825 12133 24 36 1 188 2 3 false 0.23961770394808907 0.23961770394808907 7.565886554812955E-31 nuclear_speck GO:0016607 12133 147 36 4 272 5 1 false 0.23986830806027115 0.23986830806027115 6.6218564870724965E-81 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 36 2 130 2 2 false 0.2404293381037601 0.2404293381037601 1.0680656075518395E-38 MAPK_cascade GO:0000165 12133 502 36 3 806 3 1 false 0.24105962489080368 0.24105962489080368 3.7900857366173457E-231 positive_regulation_of_biological_process GO:0048518 12133 3081 36 13 10446 36 2 false 0.2414727987082371 0.2414727987082371 0.0 cytokine-mediated_signaling_pathway GO:0019221 12133 318 36 2 2013 6 2 false 0.24225746344629015 0.24225746344629015 0.0 mitochondrial_membrane_organization GO:0007006 12133 62 36 1 924 4 2 false 0.24292691121712817 0.24292691121712817 3.431124286579491E-98 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 36 3 1256 18 1 false 0.24316079938639185 0.24316079938639185 3.1457660386089413E-171 cellular_process GO:0009987 12133 9675 36 35 10446 36 1 false 0.24428128591976717 0.24428128591976717 0.0 regulation_of_cytokine-mediated_signaling_pathway GO:0001959 12133 70 36 1 1785 7 3 false 0.24460820246409856 0.24460820246409856 1.145730192869727E-127 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 36 2 260 3 3 false 0.2447904075811306 0.2447904075811306 1.712440969539876E-70 positive_regulation_of_lyase_activity GO:0051349 12133 64 36 1 1165 5 3 false 0.24648882758154175 0.24648882758154175 4.208539259642897E-107 regulation_of_Rho_protein_signal_transduction GO:0035023 12133 149 36 2 299 2 2 false 0.24749163879601563 0.24749163879601563 2.1331125641940734E-89 defense_response GO:0006952 12133 1018 36 6 2540 11 1 false 0.24780894732635333 0.24780894732635333 0.0 neuron_development GO:0048666 12133 654 36 2 1313 2 2 false 0.24790904278045037 0.24790904278045037 0.0 single-organism_process GO:0044699 12133 8052 36 30 10446 36 1 false 0.24970914676201889 0.24970914676201889 0.0 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 36 8 4429 29 3 false 0.25129924454285885 0.25129924454285885 0.0 cysteine-type_peptidase_activity GO:0008234 12133 295 36 2 586 2 1 false 0.25299728712705444 0.25299728712705444 1.2148857586981575E-175 response_to_peptide_hormone_stimulus GO:0043434 12133 313 36 2 619 2 2 false 0.2552817729818599 0.2552817729818599 1.4916788604957572E-185 Notch_signaling_pathway GO:0007219 12133 113 36 1 1975 5 1 false 0.2553893818101397 0.2553893818101397 2.33429872590278E-187 mitotic_spindle_organization GO:0007052 12133 37 36 1 648 5 2 false 0.25539967454864687 0.25539967454864687 3.6765869552528886E-61 coagulation GO:0050817 12133 446 36 2 4095 9 1 false 0.25606191519611665 0.25606191519611665 0.0 intracellular_estrogen_receptor_signaling_pathway GO:0030520 12133 34 36 2 102 3 1 false 0.25702970297029953 0.25702970297029953 7.615480469304384E-28 mitochondrial_outer_membrane GO:0005741 12133 96 36 1 372 1 2 false 0.25806451612902936 0.25806451612902936 1.1824719222700171E-91 transcription_coactivator_activity GO:0003713 12133 264 36 4 478 5 2 false 0.25842107889828536 0.25842107889828536 4.798051856605128E-142 regulation_of_peptidyl-serine_phosphorylation GO:0033135 12133 59 36 1 818 4 2 false 0.2591922299767508 0.2591922299767508 1.6613120232447818E-91 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 36 1 953 8 4 false 0.25952715452889685 0.25952715452889685 1.0482452124052062E-64 regulation_of_response_to_interferon-gamma GO:0060330 12133 23 36 1 319 4 3 false 0.259773668381833 0.259773668381833 1.507111625705858E-35 histone_acetyltransferase_complex GO:0000123 12133 72 36 1 3138 13 2 false 0.2609130085160976 0.2609130085160976 2.423530971941831E-148 single-stranded_RNA_binding GO:0003727 12133 40 36 2 763 19 1 false 0.2623779676297048 0.2623779676297048 1.1547828689277465E-67 cytoplasmic_vesicle_part GO:0044433 12133 366 36 3 7185 35 3 false 0.2630140222654825 0.2630140222654825 0.0 positive_regulation_of_cyclase_activity GO:0031281 12133 63 36 1 1064 5 3 false 0.2634459753510187 0.2634459753510187 2.5891490792503797E-103 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 36 4 982 4 1 false 0.2635080284179177 0.2635080284179177 2.6984349291053464E-253 positive_regulation_of_DNA_repair GO:0045739 12133 26 36 1 440 5 4 false 0.26359953522455065 0.26359953522455065 1.5959457492821637E-42 regulation_of_mitochondrion_organization GO:0010821 12133 64 36 1 661 3 2 false 0.26361192497934516 0.26361192497934516 9.542606350434685E-91 response_to_endogenous_stimulus GO:0009719 12133 982 36 4 5200 14 1 false 0.2638747673147892 0.2638747673147892 0.0 site_of_polarized_growth GO:0030427 12133 87 36 1 9983 35 1 false 0.2642615504164205 0.2642615504164205 3.5589816347501575E-216 protein_complex_localization GO:0031503 12133 29 36 1 1434 15 1 false 0.2650687357839501 0.2650687357839501 3.39152835029198E-61 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 36 3 217 4 1 false 0.2670346603117034 0.2670346603117034 1.2933579260360868E-64 ERBB_signaling_pathway GO:0038127 12133 199 36 2 586 3 1 false 0.26727091927195856 0.26727091927195856 2.435227003721618E-162 transferrin_transport GO:0033572 12133 24 36 1 1099 14 2 false 0.26727459144049276 0.26727459144049276 8.291143924248354E-50 negative_regulation_of_nuclear_division GO:0051784 12133 43 36 1 436 3 3 false 0.26820422283667583 0.26820422283667583 1.634686522119006E-60 regulation_of_signaling GO:0023051 12133 1793 36 7 6715 20 2 false 0.2703579424902476 0.2703579424902476 0.0 vesicle_coat GO:0030120 12133 38 36 1 381 3 3 false 0.2710011842187785 0.2710011842187785 2.9673810590707202E-53 extracellular_vesicular_exosome GO:0070062 12133 58 36 1 763 4 2 false 0.27158906822018636 0.27158906822018636 1.4131645972383266E-88 positive_regulation_of_proteolysis GO:0045862 12133 69 36 1 1334 6 3 false 0.2733236010083115 0.2733236010083115 2.369917275782091E-117 'de_novo'_protein_folding GO:0006458 12133 51 36 1 183 1 1 false 0.27868852459015203 0.27868852459015203 1.4322240237766098E-46 positive_regulation_of_nucleotide_metabolic_process GO:0045981 12133 83 36 1 2578 10 4 false 0.27951730930985524 0.27951730930985524 1.0942419479084622E-158 regulation_of_proteasomal_protein_catabolic_process GO:0061136 12133 67 36 1 1672 8 5 false 0.2795471292231777 0.2795471292231777 1.5388096674355026E-121 regulation_of_cellular_amine_metabolic_process GO:0033238 12133 69 36 1 4026 19 3 false 0.28050022478672926 0.28050022478672926 5.643300821418702E-151 regulation_of_protein_binding GO:0043393 12133 95 36 1 6398 22 2 false 0.2808314279004033 0.2808314279004033 5.5524328548337306E-214 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 36 6 4597 13 2 false 0.28102414843775936 0.28102414843775936 0.0 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 36 6 2771 17 5 false 0.28151878262329577 0.28151878262329577 0.0 positive_regulation_of_purine_nucleotide_biosynthetic_process GO:1900373 12133 77 36 1 273 1 4 false 0.2820512820512513 0.2820512820512513 5.5014514459438226E-70 regulation_of_developmental_process GO:0050793 12133 1233 36 5 7209 21 2 false 0.28351726082130535 0.28351726082130535 0.0 sequence-specific_DNA_binding GO:0043565 12133 1189 36 4 2091 5 1 false 0.28466608552007633 0.28466608552007633 0.0 positive_regulation_of_cytokine_production GO:0001819 12133 175 36 1 614 1 3 false 0.2850162866449984 0.2850162866449984 1.2195240299259301E-158 negative_regulation_of_hydrolase_activity GO:0051346 12133 241 36 2 2738 12 3 false 0.2856229718298813 0.2856229718298813 0.0 regulation_of_steroid_biosynthetic_process GO:0050810 12133 42 36 1 146 1 3 false 0.2876712328767199 0.2876712328767199 1.231507741439357E-37 positive_regulation_of_nucleotide_biosynthetic_process GO:0030810 12133 77 36 1 1402 6 4 false 0.28790746185077565 0.28790746185077565 6.104501177954134E-129 regulation_of_response_to_cytokine_stimulus GO:0060759 12133 76 36 1 2275 10 2 false 0.28855628914248144 0.28855628914248144 4.9547358949088833E-144 cognition GO:0050890 12133 140 36 1 894 2 1 false 0.28882358688396 0.28882358688396 8.622135974354301E-168 nucleus_organization GO:0006997 12133 62 36 1 2031 11 1 false 0.2895686897635402 0.2895686897635402 6.73570952581451E-120 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 36 4 7293 28 3 false 0.2898404218208878 0.2898404218208878 0.0 negative_regulation_of_protein_complex_assembly GO:0031333 12133 63 36 1 954 5 3 false 0.2898931348811721 0.2898931348811721 3.124938390294621E-100 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 36 10 7638 35 4 false 0.29062333959878883 0.29062333959878883 0.0 positive_regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043517 12133 11 36 1 135 4 4 false 0.29106264832897105 0.29106264832897105 2.2345648964968075E-16 localization_within_membrane GO:0051668 12133 37 36 1 1845 17 1 false 0.29241952719789377 0.29241952719789377 2.8489513256034824E-78 organelle_fission GO:0048285 12133 351 36 3 2031 11 1 false 0.2928237265881272 0.2928237265881272 0.0 RNA_biosynthetic_process GO:0032774 12133 2751 36 23 4191 32 3 false 0.2932326535490221 0.2932326535490221 0.0 kinase_regulator_activity GO:0019207 12133 125 36 1 1851 5 3 false 0.2953042436456925 0.2953042436456925 5.123060762627793E-198 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 36 8 3780 28 4 false 0.2968581455366496 0.2968581455366496 0.0 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 36 3 442 4 3 false 0.2981666598174631 0.2981666598174631 2.4953498472018727E-132 histone_binding GO:0042393 12133 102 36 1 6397 22 1 false 0.2982672348273076 0.2982672348273076 1.3332295224304937E-226 intracellular_signal_transduction GO:0035556 12133 1813 36 7 3547 11 1 false 0.2997868812036169 0.2997868812036169 0.0 positive_regulation_of_cell_growth GO:0030307 12133 79 36 1 2912 13 4 false 0.30113656958041507 0.30113656958041507 5.548863790318827E-157 protein_insertion_into_membrane GO:0051205 12133 32 36 1 1452 16 3 false 0.3012321041291773 0.3012321041291773 2.4360077014496946E-66 regulation_of_endopeptidase_activity GO:0052548 12133 264 36 2 480 2 2 false 0.3019832985387032 0.3019832985387032 9.691263405564588E-143 regulation_of_ossification GO:0030278 12133 137 36 1 1586 4 2 false 0.3035254847361519 0.3035254847361519 7.69235263015688E-202 positive_regulation_of_molecular_function GO:0044093 12133 1303 36 6 10257 36 2 false 0.3040042580542498 0.3040042580542498 0.0 clathrin-coated_endocytic_vesicle_membrane GO:0030669 12133 26 36 1 157 2 3 false 0.3046709129511338 0.3046709129511338 2.9127380680410067E-30 apoptotic_mitochondrial_changes GO:0008637 12133 87 36 1 1476 6 2 false 0.3059061828171194 0.3059061828171194 5.447605955370739E-143 G1_DNA_damage_checkpoint GO:0044783 12133 70 36 2 126 2 1 false 0.30666666666666786 0.30666666666666786 3.590272155218709E-37 estrogen_receptor_binding GO:0030331 12133 23 36 2 62 3 1 false 0.30772078265469033 0.30772078265469033 1.6756493074771417E-17 regulation_of_cell_communication GO:0010646 12133 1796 36 7 6469 20 2 false 0.3080704509485832 0.3080704509485832 0.0 regulation_of_metabolic_process GO:0019222 12133 4469 36 19 9189 35 2 false 0.3081736275589494 0.3081736275589494 0.0 regulation_of_lipid_biosynthetic_process GO:0046890 12133 85 36 1 3279 14 3 false 0.3081892825564052 0.3081892825564052 1.2266874982723732E-170 mitochondrial_outer_membrane_permeabilization GO:0097345 12133 37 36 1 319 3 3 false 0.3100201715862682 0.3100201715862682 2.7662883808425E-49 activating_transcription_factor_binding GO:0033613 12133 294 36 4 715 7 1 false 0.3109939630873293 0.3109939630873293 1.6086726333731214E-209 skeletal_muscle_organ_development GO:0060538 12133 172 36 2 308 2 1 false 0.3110537670797738 0.3110537670797738 3.4535917571053045E-91 nucleoside_phosphate_binding GO:1901265 12133 1998 36 14 4407 27 2 false 0.3114888404214289 0.3114888404214289 0.0 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 36 2 442 2 3 false 0.3117246898760163 0.3117246898760163 4.945935388068452E-131 cellular_protein_catabolic_process GO:0044257 12133 409 36 4 3174 22 3 false 0.31258872155838313 0.31258872155838313 0.0 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 36 2 1384 8 2 false 0.313928389302193 0.313928389302193 1.3395090025049634E-243 poly(A)_RNA_binding GO:0008143 12133 11 36 1 94 3 2 false 0.31454596998000534 0.31454596998000534 1.4483869139240058E-14 regulation_of_MAP_kinase_activity GO:0043405 12133 268 36 3 533 4 3 false 0.3160343858982104 0.3160343858982104 1.0382438249699724E-159 cyclase_activity GO:0009975 12133 123 36 1 4901 15 1 false 0.31737586287957786 0.31737586287957786 7.077862449152851E-249 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 36 2 170 3 3 false 0.31743821789068466 0.31743821789068466 2.004129732487635E-48 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 36 2 308 2 2 false 0.31835103007736393 0.31835103007736393 5.66231040699253E-91 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 36 4 504 4 1 false 0.31850792328353605 0.31850792328353605 6.011520399617331E-122 protein_kinase_activity GO:0004672 12133 1014 36 4 1347 4 3 false 0.32066005283062343 0.32066005283062343 0.0 ribonucleotide_catabolic_process GO:0009261 12133 946 36 7 1294 8 3 false 0.3209293623817733 0.3209293623817733 0.0 ATPase_activity GO:0016887 12133 307 36 3 1069 7 2 false 0.32376199580543397 0.32376199580543397 1.5605649392254874E-277 lamellipodium GO:0030027 12133 121 36 1 990 3 2 false 0.32396346314162955 0.32396346314162955 5.739208350847419E-159 receptor_internalization GO:0031623 12133 54 36 1 2372 17 3 false 0.324856826555296 0.324856826555296 2.350294022700988E-111 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 36 2 207 3 2 false 0.32496096256869944 0.32496096256869944 2.976076769798144E-59 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 36 1 1198 6 4 false 0.3257099804954392 0.3257099804954392 2.335035261625238E-122 histone_modification GO:0016570 12133 306 36 2 2375 9 2 false 0.3263813850742677 0.3263813850742677 0.0 cell_projection_morphogenesis GO:0048858 12133 541 36 2 946 2 3 false 0.3267894895803065 0.3267894895803065 1.1683643564827775E-279 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 36 2 269 3 2 false 0.3269383627785909 0.3269383627785909 3.613555574654199E-77 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 36 2 803 4 1 false 0.32866018090599514 0.32866018090599514 7.141936114023743E-209 trans-Golgi_network GO:0005802 12133 103 36 1 7259 28 1 false 0.3302809508419107 0.3302809508419107 4.3774465508031144E-234 nucleotide_catabolic_process GO:0009166 12133 969 36 7 1318 8 2 false 0.3305583957496716 0.3305583957496716 0.0 protein_binding,_bridging GO:0030674 12133 116 36 1 6397 22 2 false 0.3318661906826375 0.3318661906826375 3.1111419589573665E-251 kinase_activity GO:0016301 12133 1174 36 4 1546 4 2 false 0.3321233580612134 0.3321233580612134 0.0 development_of_primary_sexual_characteristics GO:0045137 12133 174 36 1 3105 7 3 false 0.33241760535070497 0.33241760535070497 2.1612319791507408E-290 signaling_adaptor_activity GO:0035591 12133 65 36 1 839 5 2 false 0.3324886297435495 0.3324886297435495 9.48818477040309E-99 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 36 8 2643 13 1 false 0.33279091389384374 0.33279091389384374 0.0 histone_acetyltransferase_activity_(H4-K16_specific) GO:0046972 12133 7 36 1 21 1 2 false 0.33333333333333354 0.33333333333333354 8.599931200550419E-6 regulation_of_lyase_activity GO:0051339 12133 117 36 1 1793 6 2 false 0.3333341997274487 0.3333341997274487 4.0773224530305873E-187 negative_regulation_of_mitosis GO:0045839 12133 43 36 1 656 6 5 false 0.3352793654306263 0.3352793654306263 1.8426541499010044E-68 skeletal_muscle_tissue_development GO:0007519 12133 168 36 2 288 2 2 false 0.3394308943089065 0.3394308943089065 2.348024843062379E-84 osteoblast_differentiation GO:0001649 12133 126 36 1 2191 7 2 false 0.3397791383428188 0.3397791383428188 1.111366645898294E-208 purine_NTP-dependent_helicase_activity GO:0070035 12133 98 36 3 140 3 1 false 0.3398185799186785 0.3398185799186785 9.838676628741767E-37 synapse GO:0045202 12133 368 36 2 10701 35 1 false 0.340051511934065 0.340051511934065 0.0 regulation_of_cyclase_activity GO:0031279 12133 115 36 1 1700 6 2 false 0.34354733497930623 0.34354733497930623 4.764508019192963E-182 peptidyl-serine_phosphorylation GO:0018105 12133 121 36 1 1201 4 2 false 0.3464491110452555 0.3464491110452555 1.0029038835537004E-169 catalytic_step_2_spliceosome GO:0071013 12133 76 36 4 151 6 3 false 0.34687528062474104 0.34687528062474104 5.422089502503699E-45 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 36 2 7778 30 4 false 0.34732441459689145 0.34732441459689145 0.0 regulation_of_viral_reproduction GO:0050792 12133 101 36 1 6451 27 3 false 0.34749542174914805 0.34749542174914805 3.49743359338843E-225 organelle_outer_membrane GO:0031968 12133 110 36 1 9084 35 4 false 0.3476760649709235 0.3476760649709235 1.1973077012984011E-257 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 36 1 6380 20 3 false 0.348438949898517 0.348438949898517 2.5067679665083333E-283 cellular_response_to_nitrogen_compound GO:1901699 12133 347 36 2 1721 6 2 false 0.34864398132487306 0.34864398132487306 0.0 gonad_development GO:0008406 12133 150 36 1 2876 8 4 false 0.34887752934439875 0.34887752934439875 4.529833702866928E-255 RNA_modification GO:0009451 12133 64 36 1 4775 32 2 false 0.35158101573440126 0.35158101573440126 6.812362595459872E-147 DNA_repair GO:0006281 12133 368 36 4 977 8 2 false 0.3519624636501995 0.3519624636501995 3.284245924949814E-280 single-organism_cellular_process GO:0044763 12133 7541 36 29 9888 36 2 false 0.3520191686326115 0.3520191686326115 0.0 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 36 1 2735 15 4 false 0.352824405610372 0.352824405610372 2.836340851870023E-153 protein_kinase_regulator_activity GO:0019887 12133 106 36 1 1026 4 3 false 0.3539464174907875 0.3539464174907875 2.0818014646962408E-147 cellular_membrane_organization GO:0016044 12133 784 36 4 7541 29 2 false 0.35605001559265914 0.35605001559265914 0.0 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 36 3 1813 7 1 false 0.3566938201885953 0.3566938201885953 0.0 negative_regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042059 12133 39 36 1 197 2 3 false 0.35755723609237877 0.35755723609237877 3.777320475653026E-42 viral_assembly,_maturation,_egress,_and_release GO:0019067 12133 16 36 1 557 15 2 false 0.3578059366545341 0.3578059366545341 3.0295698614548545E-31 negative_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0043433 12133 103 36 1 1679 7 3 false 0.3585206720292864 0.3585206720292864 1.5952227787322578E-167 wound_healing GO:0042060 12133 543 36 2 905 2 1 false 0.3597345132743657 0.3597345132743657 1.120707554751266E-263 viral_protein_processing GO:0019082 12133 10 36 1 256 11 2 false 0.36064155508370915 0.36064155508370915 3.5864633505920636E-18 SAGA-type_complex GO:0070461 12133 26 36 1 72 1 1 false 0.36111111111111127 0.36111111111111127 3.624038800506386E-20 binding,_bridging GO:0060090 12133 129 36 1 8962 31 1 false 0.3625117663079275 0.3625117663079275 1.7318913122999068E-292 purine_nucleoside_catabolic_process GO:0006152 12133 939 36 7 1085 7 3 false 0.3625253405731609 0.3625253405731609 2.1746006434797338E-185 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 36 2 129 2 1 false 0.36373546511628674 0.36373546511628674 3.5310664374642874E-37 neuron_part GO:0097458 12133 612 36 3 9983 35 1 false 0.36389634928962766 0.36389634928962766 0.0 hydrolase_activity GO:0016787 12133 2556 36 9 4901 15 1 false 0.3649421275956953 0.3649421275956953 0.0 regulation_of_body_fluid_levels GO:0050878 12133 527 36 2 4595 11 2 false 0.3650788745417187 0.3650788745417187 0.0 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 36 3 1079 5 3 false 0.36525900939301365 0.36525900939301365 5.98264E-319 transferase_activity,_transferring_one-carbon_groups GO:0016741 12133 130 36 1 1779 6 1 false 0.366161023422973 0.366161023422973 2.4341608753326182E-201 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 36 2 766 2 2 false 0.3681974095123166 0.3681974095123166 4.217322594612318E-222 microtubule_cytoskeleton_organization GO:0000226 12133 259 36 2 831 4 2 false 0.3688711311510714 0.3688711311510714 4.0880234187670296E-223 protein_catabolic_process GO:0030163 12133 498 36 4 3569 22 2 false 0.36914929162177085 0.36914929162177085 0.0 RNA_localization GO:0006403 12133 131 36 2 1642 16 1 false 0.3691939801518219 0.3691939801518219 1.0675246049472868E-197 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 36 1 415 4 1 false 0.36926596345186424 0.36926596345186424 2.1919403735850567E-61 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 36 8 5303 29 3 false 0.3694251781581305 0.3694251781581305 0.0 nucleobase-containing_compound_transport GO:0015931 12133 135 36 2 1584 15 2 false 0.37017062589126226 0.37017062589126226 1.0378441909200412E-199 positive_regulation_of_defense_response GO:0031349 12133 229 36 2 1621 9 3 false 0.3702526159015582 0.3702526159015582 6.85443065618377E-286 histone_methyltransferase_complex GO:0035097 12133 60 36 1 807 6 2 false 0.37189689920773605 0.37189689920773605 3.052234764972827E-92 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 36 1 1054 5 3 false 0.3737489855731968 0.3737489855731968 5.573854633657796E-137 small_ribosomal_subunit GO:0015935 12133 60 36 6 132 11 1 false 0.3738641839840103 0.3738641839840103 4.556510204279982E-39 release_of_cytochrome_c_from_mitochondria GO:0001836 12133 46 36 1 319 3 2 false 0.3742169773070779 0.3742169773070779 1.115567120488483E-56 BMP_signaling_pathway GO:0030509 12133 83 36 1 1276 7 2 false 0.376222992540608 0.376222992540608 9.874891335860256E-133 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 36 1 2191 9 3 false 0.37694905351796826 0.37694905351796826 2.495063769189982E-191 guanyl_nucleotide_binding GO:0019001 12133 450 36 3 1650 8 1 false 0.3786855363106235 0.3786855363106235 0.0 protein_localization GO:0008104 12133 1434 36 15 1642 16 1 false 0.3789813222819668 0.3789813222819668 3.426309620265761E-270 regulation_of_DNA_repair GO:0006282 12133 46 36 1 508 5 3 false 0.3790812233625401 0.3790812233625401 1.525242689490639E-66 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 36 1 591 6 3 false 0.3795359900904546 0.3795359900904546 1.267222544612779E-68 SH3/SH2_adaptor_activity GO:0005070 12133 48 36 1 126 1 2 false 0.38095238095239137 0.38095238095239137 5.926155314091347E-36 guanyl_ribonucleotide_binding GO:0032561 12133 450 36 3 1641 8 2 false 0.3824974052970187 0.3824974052970187 0.0 anatomical_structure_development GO:0048856 12133 3099 36 9 3447 9 1 false 0.38327669664607833 0.38327669664607833 0.0 cytoplasmic_vesicle GO:0031410 12133 764 36 4 8540 35 3 false 0.3833917028850168 0.3833917028850168 0.0 positive_regulation_of_DNA_metabolic_process GO:0051054 12133 92 36 1 2322 12 4 false 0.385105259963247 0.385105259963247 1.6937907011714837E-167 ATP_catabolic_process GO:0006200 12133 318 36 3 1012 7 4 false 0.38527175996324764 0.38527175996324764 1.0026310858617265E-272 growth GO:0040007 12133 646 36 3 10446 36 1 false 0.3862899407415015 0.3862899407415015 0.0 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 36 2 252 2 2 false 0.38721305255167254 0.38721305255167254 5.925442745937436E-72 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 36 7 2595 13 2 false 0.38752102215117534 0.38752102215117534 0.0 positive_regulation_of_immune_response GO:0050778 12133 394 36 3 1600 9 4 false 0.38878495502940386 0.38878495502940386 0.0 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 36 2 183 3 2 false 0.3895480481840517 0.3895480481840517 1.0111677973178846E-53 cellular_response_to_organic_nitrogen GO:0071417 12133 323 36 2 1478 6 4 false 0.39019826288605364 0.39019826288605364 0.0 spliceosomal_complex_assembly GO:0000245 12133 38 36 2 259 9 2 false 0.3903044501102102 0.3903044501102102 1.791986159229858E-46 receptor_binding GO:0005102 12133 918 36 4 6397 22 1 false 0.39032292352571507 0.39032292352571507 0.0 envelope GO:0031975 12133 641 36 3 9983 35 1 false 0.3921721473558345 0.3921721473558345 0.0 activation_of_innate_immune_response GO:0002218 12133 155 36 2 362 3 2 false 0.39271284492129616 0.39271284492129616 1.0665156090103768E-106 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 36 7 3453 25 4 false 0.39290086582245287 0.39290086582245287 0.0 regulation_of_growth GO:0040008 12133 447 36 2 6651 20 2 false 0.3930445773530131 0.3930445773530131 0.0 cytoskeleton-dependent_intracellular_transport GO:0030705 12133 67 36 1 2454 18 2 false 0.3934902459246761 0.3934902459246761 6.842684271212845E-133 cell_motility GO:0048870 12133 785 36 2 1249 2 3 false 0.39482868345985334 0.39482868345985334 0.0 regulation_of_alternative_mRNA_splicing,_via_spliceosome GO:0000381 12133 16 36 2 37 3 2 false 0.3963963963963978 0.3963963963963978 7.76652299088412E-11 calmodulin_binding GO:0005516 12133 145 36 1 6397 22 1 false 0.3966447975220314 0.3966447975220314 5.666124490309724E-300 positive_regulation_of_immune_system_process GO:0002684 12133 540 36 3 3595 15 3 false 0.39674856013173554 0.39674856013173554 0.0 intrinsic_apoptotic_signaling_pathway_in_response_to_DNA_damage GO:0008630 12133 45 36 1 647 7 2 false 0.3977394731565038 0.3977394731565038 1.851108938674389E-70 mRNA_binding GO:0003729 12133 91 36 3 763 19 1 false 0.39978199438476536 0.39978199438476536 1.7788235024198917E-120 positive_regulation_of_adenylate_cyclase_activity GO:0045762 12133 52 36 1 130 1 5 false 0.3999999999999939 0.3999999999999939 1.4124265749856537E-37 regulation_of_primary_metabolic_process GO:0080090 12133 3921 36 19 7507 34 2 false 0.400478456719583 0.400478456719583 0.0 regulation_of_osteoblast_differentiation GO:0045667 12133 89 36 1 913 5 3 false 0.4019099112314666 0.4019099112314666 4.590259289121949E-126 rhythmic_process GO:0048511 12133 148 36 1 10446 36 1 false 0.4022413286077286 0.4022413286077286 0.0 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 36 2 129 2 1 false 0.40225290697674887 0.40225290697674887 2.4714073881998435E-36 poly-pyrimidine_tract_binding GO:0008187 12133 9 36 1 40 2 1 false 0.4038461538461555 0.4038461538461555 3.657124400158464E-9 RNA_export_from_nucleus GO:0006405 12133 72 36 2 165 3 2 false 0.4044835607307819 0.4044835607307819 1.3059643179360761E-48 positive_regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032436 12133 35 36 1 288 4 4 false 0.4061872551922686 0.4061872551922686 7.428075320192054E-46 protein_heterodimerization_activity GO:0046982 12133 317 36 1 779 1 1 false 0.4069319640564945 0.4069319640564945 8.49214053182804E-228 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 36 11 6129 35 3 false 0.40792164528125047 0.40792164528125047 0.0 ATPase_activity,_coupled GO:0042623 12133 228 36 3 307 3 1 false 0.4082343099037556 0.4082343099037556 1.7947531856464704E-75 peptidyl-lysine_acetylation GO:0018394 12133 127 36 2 198 2 2 false 0.4102445777572036 0.4102445777572036 1.293028032371008E-55 positive_regulation_of_growth GO:0045927 12133 130 36 1 3267 13 3 false 0.4107234219961013 0.4107234219961013 1.2617745932569076E-236 ossification GO:0001503 12133 234 36 1 4095 9 1 false 0.4114527470285277 0.4114527470285277 0.0 regulation_of_organelle_organization GO:0033043 12133 519 36 3 2487 11 2 false 0.411485103779478 0.411485103779478 0.0 post-Golgi_vesicle-mediated_transport GO:0006892 12133 70 36 1 170 1 1 false 0.4117647058823321 0.4117647058823321 1.5403758302393128E-49 ribonucleoside_catabolic_process GO:0042454 12133 946 36 7 1073 7 2 false 0.41294658469575013 0.41294658469575013 9.25790942536024E-169 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 36 1 222 3 3 false 0.41341011929244453 0.41341011929244453 2.5456303013282065E-42 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 36 7 1319 8 1 false 0.41492717077192454 0.41492717077192454 6.536050345296563E-309 regulation_of_mRNA_splicing,_via_spliceosome GO:0048024 12133 32 36 2 231 10 3 false 0.41493223472777246 0.41493223472777246 5.789429371590664E-40 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 36 3 2776 10 3 false 0.4154317447001965 0.4154317447001965 0.0 MLL1/2_complex GO:0044665 12133 25 36 1 60 1 1 false 0.41666666666667024 0.41666666666667024 1.9262093107921078E-17 positive_regulation_of_proteasomal_protein_catabolic_process GO:1901800 12133 36 36 1 287 4 4 false 0.41675150321113863 0.41675150321113863 1.2079535246838254E-46 regulation_of_Ras_protein_signal_transduction GO:0046578 12133 270 36 2 417 2 2 false 0.41868428334271485 0.41868428334271485 7.174398789465976E-117 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 36 7 1054 7 2 false 0.42158916916666933 0.42158916916666933 2.3625686453162704E-163 protein_C-terminus_binding GO:0008022 12133 157 36 1 6397 22 1 false 0.4216566054035673 0.4216566054035673 2.34014E-319 endomembrane_system GO:0012505 12133 1211 36 5 9983 35 1 false 0.4220225913062885 0.4220225913062885 0.0 regulation_of_molecular_function GO:0065009 12133 2079 36 8 10494 36 2 false 0.4226391351281916 0.4226391351281916 0.0 transferase_activity,_transferring_acyl_groups GO:0016746 12133 156 36 1 1779 6 1 false 0.4238936021049593 0.4238936021049593 7.715087379917376E-229 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 36 7 4298 29 4 false 0.4255879941032855 0.4255879941032855 0.0 negative_regulation_of_protein_serine/threonine_kinase_activity GO:0071901 12133 98 36 1 757 4 3 false 0.42635324047139317 0.42635324047139317 4.731915708065017E-126 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 36 7 1060 7 3 false 0.4269770496985339 0.4269770496985339 8.715047292960447E-163 negative_regulation_of_mRNA_splicing,_via_spliceosome GO:0048025 12133 11 36 1 207 10 4 false 0.4280133967482149 0.4280133967482149 1.749347829328537E-18 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 36 6 3771 25 4 false 0.4287101189292836 0.4287101189292836 0.0 nuclear_export GO:0051168 12133 116 36 3 688 14 2 false 0.42899660363320025 0.42899660363320025 6.892155989004194E-135 epidermis_development GO:0008544 12133 219 36 1 2065 5 2 false 0.4294308116791198 0.4294308116791198 1.803818193118923E-302 epithelial_cell_proliferation GO:0050673 12133 225 36 1 1316 3 1 false 0.4304889945670155 0.4304889945670155 1.264012364925543E-260 microtubule-based_process GO:0007017 12133 378 36 2 7541 29 1 false 0.43076733429673714 0.43076733429673714 0.0 positive_regulation_of_purine_nucleotide_metabolic_process GO:1900544 12133 82 36 1 1209 8 3 false 0.43082482886000517 0.43082482886000517 1.376514335843937E-129 regulation_of_protein_phosphorylation GO:0001932 12133 787 36 4 1444 6 3 false 0.43127259341084334 0.43127259341084334 0.0 ubiquitin-protein_ligase_activity GO:0004842 12133 321 36 3 558 4 2 false 0.43253597110099384 0.43253597110099384 1.7708856343357755E-164 cyclic_nucleotide_biosynthetic_process GO:0009190 12133 151 36 1 348 1 2 false 0.4339080459770588 0.4339080459770588 8.533554981861938E-103 peptidyl-amino_acid_modification GO:0018193 12133 623 36 3 2370 9 1 false 0.4354159023753748 0.4354159023753748 0.0 organophosphate_metabolic_process GO:0019637 12133 1549 36 8 7521 35 2 false 0.43546388832139 0.43546388832139 0.0 cAMP_biosynthetic_process GO:0006171 12133 124 36 1 284 1 3 false 0.4366197183098948 0.4366197183098948 6.647675853046176E-84 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 36 6 4044 25 3 false 0.4371130368679935 0.4371130368679935 0.0 histone_acetyltransferase_activity_(H4-K5_specific) GO:0043995 12133 7 36 1 16 1 2 false 0.4374999999999999 0.4374999999999999 8.741258741258732E-5 histone_acetyltransferase_activity_(H4-K8_specific) GO:0043996 12133 7 36 1 16 1 2 false 0.4374999999999999 0.4374999999999999 8.741258741258732E-5 regulation_of_cell_growth GO:0001558 12133 243 36 2 1344 8 3 false 0.43937864601696686 0.43937864601696686 4.9010314548000585E-275 chemotaxis GO:0006935 12133 488 36 2 2369 7 2 false 0.4398532956410047 0.4398532956410047 0.0 regulation_of_protein_metabolic_process GO:0051246 12133 1388 36 8 5563 29 3 false 0.4407571084232671 0.4407571084232671 0.0 clathrin-coated_vesicle_membrane GO:0030665 12133 87 36 1 197 1 2 false 0.44162436548220174 0.44162436548220174 3.3450134544276105E-58 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I GO:0042590 12133 73 36 2 158 3 2 false 0.4427836937713481 0.4427836937713481 6.794891168245598E-47 purine_nucleotide_metabolic_process GO:0006163 12133 1208 36 8 1337 8 2 false 0.4431075164595117 0.4431075164595117 1.5771526523631757E-183 positive_regulation_of_innate_immune_response GO:0045089 12133 178 36 2 740 6 4 false 0.4438122558707972 0.4438122558707972 1.4450011889246649E-176 GTPase_binding GO:0051020 12133 137 36 1 1005 4 1 false 0.4440901195648054 0.4440901195648054 4.2154504665352884E-173 reproductive_system_development GO:0061458 12133 216 36 1 2686 7 1 false 0.44430155265292326 0.44430155265292326 0.0 regulation_of_purine_nucleotide_biosynthetic_process GO:1900371 12133 146 36 1 574 2 3 false 0.4443451240795597 0.4443451240795597 1.1371703790830463E-140 positive_regulation_of_cyclic_nucleotide_metabolic_process GO:0030801 12133 80 36 1 180 1 3 false 0.44444444444442294 0.44444444444442294 3.3247573319336413E-53 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 36 3 3702 14 3 false 0.4459149693304998 0.4459149693304998 0.0 circadian_rhythm GO:0007623 12133 66 36 1 148 1 1 false 0.4459459459459285 0.4459459459459285 1.0122432742541851E-43 cellular_response_to_insulin_stimulus GO:0032869 12133 185 36 2 276 2 2 false 0.44848484848485837 0.44848484848485837 1.999097443178639E-75 purine_nucleotide_catabolic_process GO:0006195 12133 956 36 7 1223 8 3 false 0.45024663273344123 0.45024663273344123 6.80299167777575E-278 response_to_organic_substance GO:0010033 12133 1783 36 6 2369 7 1 false 0.45128617955996597 0.45128617955996597 0.0 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 36 1 242 3 2 false 0.45380988306300024 0.45380988306300024 2.220259827778367E-49 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 36 2 134 3 2 false 0.4549382275226906 0.4549382275226906 8.460684206886756E-40 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 36 3 136 3 2 false 0.4571749097649283 0.4571749097649283 2.4301849830786213E-31 positive_regulation_of_cAMP_metabolic_process GO:0030816 12133 71 36 1 155 1 4 false 0.4580645161290261 0.4580645161290261 5.885583975701031E-46 regulation_of_actin_filament-based_process GO:0032970 12133 192 36 1 6365 20 2 false 0.4585562823011354 0.4585562823011354 0.0 regulation_of_nucleotide_biosynthetic_process GO:0030808 12133 146 36 1 3406 14 3 false 0.4591207439579049 0.4591207439579049 5.390613252169377E-261 transport_vesicle_membrane GO:0030658 12133 63 36 1 340 3 2 false 0.46033254376255656 0.46033254376255656 3.001775130471713E-70 enzyme_binding GO:0019899 12133 1005 36 4 6397 22 1 false 0.4623765378337084 0.4623765378337084 0.0 cell_part_morphogenesis GO:0032990 12133 551 36 2 810 2 1 false 0.4624669993438532 0.4624669993438532 1.1709501739830369E-219 intrinsic_apoptotic_signaling_pathway_by_p53_class_mediator GO:0072332 12133 32 36 1 224 4 2 false 0.4626566586471379 0.4626566586471379 1.6688930470931678E-39 covalent_chromatin_modification GO:0016569 12133 312 36 2 458 2 1 false 0.46358919476766813 0.46358919476766813 7.826311589520491E-124 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 36 7 1202 8 3 false 0.46527774151588014 0.46527774151588014 1.616697592155103E-269 regulation_of_multicellular_organismal_development GO:2000026 12133 953 36 3 3481 9 3 false 0.4657758428371102 0.4657758428371102 0.0 learning_or_memory GO:0007611 12133 131 36 1 281 1 2 false 0.46619217081854175 0.46619217081854175 1.0269741114888063E-83 negative_regulation_of_kinase_activity GO:0033673 12133 172 36 1 1181 4 3 false 0.4676611658290511 0.4676611658290511 3.9159843646516213E-212 regulation_of_small_GTPase_mediated_signal_transduction GO:0051056 12133 335 36 2 1759 8 2 false 0.4686046040516834 0.4686046040516834 0.0 small_conjugating_protein_ligase_binding GO:0044389 12133 147 36 1 1005 4 1 false 0.46931164239002787 0.46931164239002787 6.302468729220369E-181 response_to_chemical_stimulus GO:0042221 12133 2369 36 7 5200 14 1 false 0.47081823800583333 0.47081823800583333 0.0 regulation_of_defense_response GO:0031347 12133 387 36 3 1253 8 2 false 0.4708451169793781 0.4708451169793781 0.0 negative_regulation_of_phosphorylation GO:0042326 12133 215 36 1 1463 4 3 false 0.47085626059389296 0.47085626059389296 2.1310280163327356E-264 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 36 3 1350 6 4 false 0.4710655133377563 0.4710655133377563 0.0 amide_binding GO:0033218 12133 182 36 1 8962 31 1 false 0.47117899962002197 0.47117899962002197 0.0 receptor_metabolic_process GO:0043112 12133 101 36 1 5613 35 1 false 0.47137370205272444 0.47137370205272444 4.997034842501505E-219 reproductive_behavior GO:0019098 12133 57 36 1 1554 17 2 false 0.47198574614884947 0.47198574614884947 1.4014382835539594E-105 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 36 1 230 3 4 false 0.47276488163630914 0.47276488163630914 2.6271911283291635E-48 negative_regulation_of_cell_growth GO:0030308 12133 117 36 1 2621 14 4 false 0.4732127958284372 0.4732127958284372 6.020174158767381E-207 cyclin-dependent_protein_serine/threonine_kinase_activity GO:0004693 12133 105 36 1 709 4 2 false 0.4740776754513366 0.4740776754513366 1.7307728384071896E-128 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 36 8 7451 35 1 false 0.47428068869357265 0.47428068869357265 0.0 regulation_of_cellular_ketone_metabolic_process GO:0010565 12133 133 36 1 3992 19 2 false 0.47548550975691595 0.47548550975691595 1.512735013638228E-252 response_to_insulin_stimulus GO:0032868 12133 216 36 2 313 2 1 false 0.4755468173998091 0.4755468173998091 1.4650294580642456E-83 cellular_response_to_hormone_stimulus GO:0032870 12133 384 36 2 1510 6 3 false 0.47646205918422624 0.47646205918422624 0.0 Fc-gamma_receptor_signaling_pathway_involved_in_phagocytosis GO:0038096 12133 72 36 1 151 1 4 false 0.47682119205296153 0.47682119205296153 6.349846956956757E-45 DNA_damage_checkpoint GO:0000077 12133 126 36 2 574 7 2 false 0.4769767692049086 0.4769767692049086 1.5833464450994651E-130 reproductive_structure_development GO:0048608 12133 216 36 1 3110 9 3 false 0.47728217163690634 0.47728217163690634 0.0 ribonucleotide_metabolic_process GO:0009259 12133 1202 36 8 1318 8 2 false 0.4775496292643561 0.4775496292643561 7.680938106405399E-170 positive_regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030804 12133 75 36 1 157 1 4 false 0.4777070063694132 0.4777070063694132 1.0054402594300752E-46 transferase_activity GO:0016740 12133 1779 36 6 4901 15 1 false 0.47821860347250894 0.47821860347250894 0.0 vesicle GO:0031982 12133 834 36 4 7980 34 1 false 0.48157330256720754 0.48157330256720754 0.0 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 36 2 305 3 2 false 0.4827330662315472 0.4827330662315472 3.640759676212702E-91 transport_vesicle GO:0030133 12133 108 36 1 712 4 1 false 0.4829041697207299 0.4829041697207299 5.898553548536589E-131 nucleotide_binding GO:0000166 12133 1997 36 14 2103 14 2 false 0.4836611270755025 0.4836611270755025 1.0169073992212018E-181 response_to_virus GO:0009615 12133 230 36 1 475 1 1 false 0.4842105263158639 0.4842105263158639 3.548520767075247E-142 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 36 4 1304 4 1 false 0.4859659676585038 0.4859659676585038 1.004636319027547E-252 regulation_of_DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0043516 12133 24 36 1 158 4 3 false 0.4862064708990378 0.4862064708990378 6.672081748801047E-29 ATP_metabolic_process GO:0046034 12133 381 36 3 1209 8 3 false 0.4867210697776764 0.4867210697776764 0.0 regulation_of_proteolysis GO:0030162 12133 146 36 1 1822 8 2 false 0.4880564615462713 0.4880564615462713 4.197674460173735E-220 steroid_biosynthetic_process GO:0006694 12133 98 36 1 3573 24 3 false 0.4881146396496141 0.4881146396496141 2.291833143174281E-194 cell_cycle_phase_transition GO:0044770 12133 415 36 4 953 8 1 false 0.48905571228938366 0.48905571228938366 1.4433288987581492E-282 interferon-gamma-mediated_signaling_pathway GO:0060333 12133 66 36 1 330 3 2 false 0.48916895247977954 0.48916895247977954 3.5052495329479947E-71 regulation_of_programmed_cell_death GO:0043067 12133 1031 36 5 1410 6 2 false 0.48966634970962875 0.48966634970962875 0.0 regulation_of_cAMP_metabolic_process GO:0030814 12133 133 36 1 465 2 3 false 0.49067482387843386 0.49067482387843386 3.255746313776628E-120 negative_regulation_of_protein_kinase_activity GO:0006469 12133 163 36 1 1050 4 4 false 0.49127846097497113 0.49127846097497113 4.119509868513009E-196 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 36 5 2877 14 6 false 0.4931298037049149 0.4931298037049149 0.0 regulation_of_reproductive_process GO:2000241 12133 171 36 1 6891 27 2 false 0.4932599233351038 0.4932599233351038 0.0 kinase_binding GO:0019900 12133 384 36 2 1005 4 1 false 0.4937661184484529 0.4937661184484529 2.0091697589355545E-289 neurological_system_process GO:0050877 12133 894 36 2 1272 2 1 false 0.49380594688473517 0.49380594688473517 0.0 DNA-dependent_transcription,_termination GO:0006353 12133 80 36 1 2751 23 2 false 0.49416030085142254 0.49416030085142254 1.5820458311792457E-156 ATP-dependent_RNA_helicase_activity GO:0004004 12133 20 36 1 99 3 3 false 0.4958271968581023 0.4958271968581023 2.332161908415525E-21 peptidyl-serine_modification GO:0018209 12133 127 36 1 623 3 1 false 0.4959846157034221 0.4959846157034221 3.781982241942545E-136 nuclear_matrix GO:0016363 12133 81 36 1 2767 23 2 false 0.496472258007146 0.496472258007146 2.9785824972298125E-158 positive_regulation_of_nucleocytoplasmic_transport GO:0046824 12133 75 36 1 367 3 3 false 0.4973868763121823 0.4973868763121823 3.7707577442500014E-80 cellular_component GO:0005575 12133 10701 36 35 11221 36 1 false 0.4978428972429526 0.4978428972429526 0.0 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 36 2 3842 15 3 false 0.49862538237484433 0.49862538237484433 0.0 actin_filament-based_process GO:0030029 12133 431 36 2 7541 29 1 false 0.49992285779579954 0.49992285779579954 0.0 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 36 1 195 2 4 false 0.5002379064234905 0.5002379064234905 1.081664723883568E-50 cell_cortex GO:0005938 12133 175 36 1 6402 25 2 false 0.5005333724171726 0.5005333724171726 0.0 neuron_projection_development GO:0031175 12133 575 36 2 812 2 2 false 0.5011905268082553 0.5011905268082553 3.771933680434825E-212 regulation_of_catalytic_activity GO:0050790 12133 1692 36 6 6953 23 3 false 0.501831150855078 0.501831150855078 0.0 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 36 3 1730 7 2 false 0.502860474110977 0.502860474110977 0.0 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 36 1 1663 8 2 false 0.503324533095914 0.503324533095914 7.181952736648417E-207 regulation_of_apoptotic_process GO:0042981 12133 1019 36 5 1381 6 2 false 0.5051377363330074 0.5051377363330074 0.0 cyclin-dependent_protein_kinase_activity GO:0097472 12133 105 36 1 1997 13 2 false 0.5055590549363919 0.5055590549363919 5.046200754373572E-178 protein_domain_specific_binding GO:0019904 12133 486 36 2 6397 22 1 false 0.5064961244651727 0.5064961244651727 0.0 amine_metabolic_process GO:0009308 12133 139 36 1 1841 9 1 false 0.5074434389378072 0.5074434389378072 2.897401461446105E-213 purine-containing_compound_metabolic_process GO:0072521 12133 1232 36 8 5323 33 5 false 0.5078317933953944 0.5078317933953944 0.0 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 36 9 7461 35 2 false 0.5079820449413268 0.5079820449413268 0.0 histone_H4-K5_acetylation GO:0043981 12133 13 36 1 44 2 1 false 0.5084566596194499 0.5084566596194499 1.9262060287683342E-11 histone_H4-K8_acetylation GO:0043982 12133 13 36 1 44 2 1 false 0.5084566596194499 0.5084566596194499 1.9262060287683342E-11 cell_division GO:0051301 12133 438 36 2 7541 29 1 false 0.5086830723559526 0.5086830723559526 0.0 negative_regulation_of_transferase_activity GO:0051348 12133 180 36 1 2118 8 3 false 0.5092187534779394 0.5092187534779394 1.0892582554699503E-266 protein_polymerization GO:0051258 12133 145 36 1 284 1 1 false 0.5105633802817375 0.5105633802817375 7.244587792673789E-85 cellular_ketone_metabolic_process GO:0042180 12133 155 36 1 7667 35 3 false 0.5115090552554671 0.5115090552554671 0.0 response_to_nitrogen_compound GO:1901698 12133 552 36 2 2369 7 1 false 0.5120172715210006 0.5120172715210006 0.0 nuclear_envelope GO:0005635 12133 258 36 2 3962 26 3 false 0.512542206861832 0.512542206861832 0.0 lyase_activity GO:0016829 12133 230 36 1 4901 15 1 false 0.5142437530093671 0.5142437530093671 0.0 positive_regulation_of_cAMP_biosynthetic_process GO:0030819 12133 69 36 1 134 1 5 false 0.5149253731343213 0.5149253731343213 7.0817799397690005E-40 regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042058 12133 60 36 1 198 2 2 false 0.5153053376402926 0.5153053376402926 2.9049351003528108E-52 small_molecule_metabolic_process GO:0044281 12133 2423 36 9 2877 10 1 false 0.5156524346215281 0.5156524346215281 0.0 death GO:0016265 12133 1528 36 6 8052 30 1 false 0.5163003460332574 0.5163003460332574 0.0 signal_transduction GO:0007165 12133 3547 36 11 6702 20 4 false 0.5168930655793619 0.5168930655793619 0.0 male_gonad_development GO:0008584 12133 84 36 1 162 1 2 false 0.5185185185184836 0.5185185185184836 3.0520910486495067E-48 protein_maturation GO:0051604 12133 123 36 1 5551 33 2 false 0.5236519468941753 0.5236519468941753 1.3126924681575497E-255 negative_regulation_of_cell_differentiation GO:0045596 12133 381 36 2 3552 16 4 false 0.5247710834868882 0.5247710834868882 0.0 negative_regulation_of_developmental_process GO:0051093 12133 463 36 2 4566 17 3 false 0.5264063814798751 0.5264063814798751 0.0 positive_regulation_of_cellular_catabolic_process GO:0031331 12133 106 36 1 3311 23 4 false 0.5280662978909599 0.5280662978909599 4.802217577498734E-203 organelle_envelope GO:0031967 12133 629 36 3 7756 34 3 false 0.5284310166712191 0.5284310166712191 0.0 regulation_of_nuclear_division GO:0051783 12133 100 36 1 712 5 2 false 0.5318813937193715 0.5318813937193715 7.811073934054147E-125 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 36 1 162 3 5 false 0.5320048309178562 0.5320048309178562 7.1760328941400225E-37 spindle_checkpoint GO:0031577 12133 45 36 1 202 3 1 false 0.5325033249593265 0.5325033249593265 4.3818533729449334E-46 polysome GO:0005844 12133 22 36 1 569 19 1 false 0.5330635475721295 0.5330635475721295 4.138788255326549E-40 phosphorus-oxygen_lyase_activity GO:0016849 12133 123 36 1 230 1 1 false 0.5347826086956033 0.5347826086956033 1.920154677041111E-68 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 36 3 86 3 2 false 0.5348837209302556 0.5348837209302556 1.0344828145516245E-17 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 36 3 81 3 2 false 0.536333802156596 0.536333802156596 1.2278945146862784E-16 regulation_of_multi-organism_process GO:0043900 12133 193 36 1 6817 27 2 false 0.5401919664353276 0.5401919664353276 0.0 protein_K48-linked_ubiquitination GO:0070936 12133 37 36 1 163 3 1 false 0.5406182389377663 0.5406182389377663 1.6289154422281443E-37 U5_snRNP GO:0005682 12133 80 36 4 93 4 1 false 0.5416861461742352 0.5416861461742352 3.852654648545616E-16 development_of_primary_male_sexual_characteristics GO:0046546 12133 97 36 1 179 1 2 false 0.5418994413407667 0.5418994413407667 4.0970386268467766E-53 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 36 3 929 9 2 false 0.5443624245009631 0.5443624245009631 1.7613668775256747E-246 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 36 5 723 7 2 false 0.5450533545307341 0.5450533545307341 2.0953844092707462E-201 regulation_of_cyclic_nucleotide_metabolic_process GO:0030799 12133 156 36 1 478 2 2 false 0.546669824478405 0.546669824478405 1.998151187516486E-130 regulation_of_cyclin-dependent_protein_serine/threonine_kinase_activity GO:0000079 12133 77 36 1 918 9 3 false 0.5470916174633245 0.5470916174633245 2.8017058584530626E-114 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 36 1 254 2 3 false 0.5476331268866782 0.5476331268866782 3.7262148804586973E-69 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 36 8 5657 33 2 false 0.54790385620506 0.54790385620506 0.0 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 36 1 835 3 2 false 0.5481010480268099 0.5481010480268099 8.0742416973675315E-196 cell_death GO:0008219 12133 1525 36 6 7542 29 2 false 0.5486300295746761 0.5486300295746761 0.0 extracellular_structure_organization GO:0043062 12133 201 36 1 7663 30 2 false 0.5501924202217027 0.5501924202217027 0.0 regulation_of_neuron_differentiation GO:0045664 12133 281 36 1 853 2 2 false 0.5505891936221661 0.5505891936221661 5.679328733626827E-234 cytoplasm GO:0005737 12133 6938 36 27 9083 35 1 false 0.5510382499238686 0.5510382499238686 0.0 angiogenesis GO:0001525 12133 300 36 1 2776 7 3 false 0.5513377561505676 0.5513377561505676 0.0 regulation_of_neurogenesis GO:0050767 12133 344 36 1 1039 2 4 false 0.5527695408919286 0.5527695408919286 1.1807712079388562E-285 mitosis GO:0007067 12133 326 36 3 953 8 2 false 0.5536295219979958 0.5536295219979958 4.8424843971573165E-265 neuron_projection_morphogenesis GO:0048812 12133 475 36 2 637 2 2 false 0.5557447942891761 0.5557447942891761 3.7535814082411355E-156 regulation_of_lipid_metabolic_process GO:0019216 12133 182 36 1 4352 19 2 false 0.5566474042033249 0.5566474042033249 0.0 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 36 1 522 3 3 false 0.5575571360930117 0.5575571360930117 1.2617392241842968E-123 synaptic_transmission GO:0007268 12133 515 36 1 923 1 2 false 0.5579631635971848 0.5579631635971848 2.6714189194289816E-274 positive_regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900740 12133 24 36 1 43 1 3 false 0.558139534883719 0.558139534883719 1.2492622608986976E-12 DNA_metabolic_process GO:0006259 12133 791 36 5 5627 35 2 false 0.5583416394957534 0.5583416394957534 0.0 response_to_organic_nitrogen GO:0010243 12133 519 36 2 1787 6 3 false 0.559195925939085 0.559195925939085 0.0 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_I GO:0002474 12133 88 36 2 163 3 1 false 0.560059049256149 0.560059049256149 2.2957799692832176E-48 chromatin GO:0000785 12133 287 36 1 512 1 1 false 0.5605468749999285 0.5605468749999285 9.050120143931621E-152 programmed_cell_death GO:0012501 12133 1385 36 6 1525 6 1 false 0.5605917255489891 0.5605917255489891 2.142172117700311E-202 cyclic_purine_nucleotide_metabolic_process GO:0052652 12133 151 36 1 269 1 2 false 0.5613382899628113 0.5613382899628113 1.6379011785432358E-79 nuclear_periphery GO:0034399 12133 97 36 1 2767 23 2 false 0.5613706332677639 0.5613706332677639 7.041791399430774E-182 endosome_membrane GO:0010008 12133 248 36 1 1627 5 2 false 0.5630793693628897 0.5630793693628897 8.244139595488818E-301 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 36 3 185 3 1 false 0.5637302305870661 0.5637302305870661 1.2806047113744547E-36 cellular_component_organization GO:0016043 12133 3745 36 23 3839 23 1 false 0.5644871747650788 0.5644871747650788 4.153510440731863E-191 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 36 2 116 3 3 false 0.5650595754754305 0.5650595754754305 2.4978330889301296E-34 cytokine_production GO:0001816 12133 362 36 1 4095 9 1 false 0.5656238454314738 0.5656238454314738 0.0 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 36 1 53 1 2 false 0.5660377358490526 0.5660377358490526 1.6040955778771873E-15 negative_regulation_of_growth GO:0045926 12133 169 36 1 2922 14 3 false 0.5665579226153027 0.5665579226153027 1.2080528965902671E-279 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 36 7 1007 7 2 false 0.5677274042380673 0.5677274042380673 1.4040993054667365E-118 cellular_macromolecular_complex_assembly GO:0034622 12133 517 36 4 973 7 1 false 0.5685113537469348 0.5685113537469348 3.312522477266262E-291 visual_learning GO:0008542 12133 28 36 1 49 1 2 false 0.5714285714285765 0.5714285714285765 2.560824792650351E-14 regulation_of_DNA_metabolic_process GO:0051052 12133 188 36 1 4316 19 3 false 0.5717268372277852 0.5717268372277852 0.0 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 36 11 106 11 2 false 0.5717388805677847 0.5717388805677847 9.867686559172291E-9 cell_body GO:0044297 12133 239 36 1 9983 35 1 false 0.5724068215331417 0.5724068215331417 0.0 DNA-dependent_transcription,_initiation GO:0006352 12133 225 36 2 2751 23 2 false 0.5726578973356875 0.5726578973356875 0.0 negative_regulation_of_translation GO:0017148 12133 61 36 1 1470 20 4 false 0.5739890132803207 0.5739890132803207 1.1152524521517982E-109 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 36 7 1006 7 2 false 0.5760372603932314 0.5760372603932314 2.1893990019353197E-116 regulation_of_actin_cytoskeleton_organization GO:0032956 12133 166 36 1 476 2 3 false 0.576337903582687 0.576337903582687 5.437988564533384E-133 methylation GO:0032259 12133 195 36 1 8027 35 1 false 0.5779385282750358 0.5779385282750358 0.0 associative_learning GO:0008306 12133 44 36 1 76 1 1 false 0.5789473684210446 0.5789473684210446 3.7097596914648285E-22 learning GO:0007612 12133 76 36 1 131 1 1 false 0.5801526717557172 0.5801526717557172 2.825801007751668E-38 poly-purine_tract_binding GO:0070717 12133 14 36 1 40 2 1 false 0.5833333333333363 0.5833333333333363 4.309057712047628E-11 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 36 2 2935 16 1 false 0.5838565044344686 0.5838565044344686 0.0 cytoskeleton_organization GO:0007010 12133 719 36 4 2031 11 1 false 0.5858996503730581 0.5858996503730581 0.0 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 36 7 1002 7 3 false 0.5879189933528501 0.5879189933528501 5.68242981185093E-113 clathrin_coat GO:0030118 12133 39 36 1 66 1 1 false 0.5909090909090968 0.5909090909090968 4.080314872103393E-19 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 36 2 1804 6 2 false 0.5917992865994824 0.5917992865994824 0.0 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 36 2 630 5 2 false 0.5918985760587971 0.5918985760587971 4.4826406352842784E-178 cell_leading_edge GO:0031252 12133 252 36 1 9983 35 1 false 0.5919605435584503 0.5919605435584503 0.0 regulation_of_mitosis GO:0007088 12133 100 36 1 611 5 4 false 0.592150511524137 0.592150511524137 1.2375244614825155E-117 cellular_amine_metabolic_process GO:0044106 12133 136 36 1 5073 33 2 false 0.5932831619148737 0.5932831619148737 2.7563154132003715E-271 sex_differentiation GO:0007548 12133 202 36 1 340 1 1 false 0.5941176470587681 0.5941176470587681 4.342696063294865E-99 RNA_stabilization GO:0043489 12133 22 36 1 37 1 1 false 0.5945945945945961 0.5945945945945961 1.0678969112465738E-10 negative_regulation_of_organelle_organization GO:0010639 12133 168 36 1 2125 11 3 false 0.5967424360686424 0.5967424360686424 2.2467097914760192E-254 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 36 1 217 4 1 false 0.598898890276598 0.598898890276598 4.514459380304185E-47 regulation_of_androgen_receptor_signaling_pathway GO:0060765 12133 21 36 1 81 3 2 false 0.5989217065166448 0.5989217065166448 7.333410898212426E-20 iron_ion_transport GO:0006826 12133 36 36 1 60 1 1 false 0.6000000000000054 0.6000000000000054 2.7737414075406367E-17 regulation_of_catabolic_process GO:0009894 12133 554 36 3 5455 30 2 false 0.6002041382742789 0.6002041382742789 0.0 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 36 1 650 3 2 false 0.6004706122502991 0.6004706122502991 6.010278185218431E-162 cellular_component_biogenesis GO:0044085 12133 1525 36 9 3839 23 1 false 0.601535757164912 0.601535757164912 0.0 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 36 2 90 2 3 false 0.6029962546816539 0.6029962546816539 1.9615250672171495E-20 N-acyltransferase_activity GO:0016410 12133 79 36 1 131 1 1 false 0.6030534351144949 0.6030534351144949 8.517686978921233E-38 regulation_of_cytokine_production GO:0001817 12133 323 36 1 1562 4 2 false 0.6045191350762629 0.6045191350762629 0.0 protein_stabilization GO:0050821 12133 60 36 1 99 1 1 false 0.6060606060605888 0.6060606060605888 1.818679918792965E-28 mitochondrial_transport GO:0006839 12133 124 36 1 2454 18 2 false 0.6080628360928736 0.6080628360928736 1.607876790046367E-212 protein_binding GO:0005515 12133 6397 36 22 8962 31 1 false 0.6086732497555334 0.6086732497555334 0.0 macromolecule_methylation GO:0043414 12133 149 36 1 5645 35 3 false 0.6090231356260163 0.6090231356260163 2.745935058350772E-298 ion_transmembrane_transport GO:0034220 12133 556 36 2 970 3 2 false 0.6091205314829233 0.6091205314829233 1.3121997139332702E-286 regulatory_region_DNA_binding GO:0000975 12133 1169 36 3 2091 5 2 false 0.6098197852468229 0.6098197852468229 0.0 acetyltransferase_activity GO:0016407 12133 80 36 1 131 1 1 false 0.6106870229007448 0.6106870229007448 1.3104133813724972E-37 chromatin_organization GO:0006325 12133 539 36 2 689 2 1 false 0.6117350727373879 0.6117350727373879 4.375882251809235E-156 immune_response-activating_signal_transduction GO:0002757 12133 299 36 3 352 3 2 false 0.6119642857143206 0.6119642857143206 2.8561568566531905E-64 spindle_organization GO:0007051 12133 78 36 1 1776 21 3 false 0.612732069484281 0.612732069484281 2.2015050227101385E-138 regulation_of_nervous_system_development GO:0051960 12133 381 36 1 1805 4 2 false 0.612970284335919 0.612970284335919 0.0 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 36 2 309 3 2 false 0.6135613066606223 0.6135613066606223 7.558729588417702E-91 positive_regulation_of_catabolic_process GO:0009896 12133 137 36 1 3517 24 3 false 0.6158717575600374 0.6158717575600374 1.0965595914697655E-250 mitotic_spindle_checkpoint GO:0071174 12133 38 36 1 140 3 2 false 0.6163814290182628 0.6163814290182628 3.73538767395573E-35 histone_acetyltransferase_activity GO:0004402 12133 52 36 1 137 2 2 false 0.6167883211678566 0.6167883211678566 4.532765208696966E-39 nuclear_hormone_receptor_binding GO:0035257 12133 104 36 3 122 3 1 false 0.6167998916136486 0.6167998916136486 6.677251530520905E-22 receptor-mediated_endocytosis GO:0006898 12133 157 36 1 411 2 1 false 0.6186457776988368 0.6186457776988368 4.873503831957431E-118 purine_nucleoside_metabolic_process GO:0042278 12133 1054 36 7 1257 8 2 false 0.6207239376425457 0.6207239376425457 1.399683863089717E-240 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 36 1 768 1 1 false 0.6210937499998362 0.6210937499998362 1.6461815804374103E-220 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 36 2 129 2 1 false 0.6239098837209381 0.6239098837209381 2.104544859412626E-28 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 36 19 6638 35 2 false 0.6249151254838698 0.6249151254838698 0.0 blood_vessel_morphogenesis GO:0048514 12133 368 36 1 2812 7 3 false 0.6257928928035034 0.6257928928035034 0.0 in_utero_embryonic_development GO:0001701 12133 295 36 1 471 1 1 false 0.6263269639064891 0.6263269639064891 1.719393530200133E-134 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 36 8 2560 14 2 false 0.6270854479538226 0.6270854479538226 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 36 3 6358 20 2 false 0.6292246407767078 0.6292246407767078 0.0 methyltransferase_activity GO:0008168 12133 126 36 1 199 1 2 false 0.6331658291457181 0.6331658291457181 2.689097193899432E-56 endosomal_transport GO:0016197 12133 133 36 1 2454 18 2 false 0.6345304025922487 0.6345304025922487 7.966947585336105E-224 cellular_component_assembly GO:0022607 12133 1392 36 8 3836 23 2 false 0.636565105340456 0.636565105340456 0.0 microtubule GO:0005874 12133 288 36 1 3267 11 3 false 0.6382349341988355 0.6382349341988355 0.0 negative_regulation_of_protein_phosphorylation GO:0001933 12133 204 36 1 1311 6 4 false 0.6382978720317516 0.6382978720317516 2.3779440904857207E-245 heart_development GO:0007507 12133 343 36 1 2876 8 3 false 0.6384262853688699 0.6384262853688699 0.0 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 36 11 181 11 1 false 0.6398072589030286 0.6398072589030286 8.905994863592909E-13 egress_of_virus_within_host_cell GO:0046788 12133 11 36 1 28 2 2 false 0.640211640211643 0.640211640211643 4.656755228837597E-8 nuclear_membrane GO:0031965 12133 157 36 1 4084 26 3 false 0.6402782085966243 0.6402782085966243 2.8056123615014062E-288 cAMP_metabolic_process GO:0046058 12133 143 36 1 1194 8 2 false 0.6407513222877701 0.6407513222877701 2.6525041284959264E-189 endopeptidase_activity GO:0004175 12133 470 36 2 586 2 1 false 0.6430092471047486 0.6430092471047486 5.73935751356398E-126 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 36 4 645 4 1 false 0.6441728204422068 0.6441728204422068 7.3138241320053254E-93 single-organism_behavior GO:0044708 12133 277 36 1 429 1 1 false 0.6456876456877225 0.6456876456877225 1.897799858204766E-120 Fc_receptor_signaling_pathway GO:0038093 12133 76 36 1 188 2 1 false 0.6463761520081255 0.6463761520081255 1.381050418692459E-54 blood_coagulation GO:0007596 12133 443 36 2 550 2 3 false 0.6484716012585028 0.6484716012585028 4.662213706291943E-117 regulation_of_Rho_GTPase_activity GO:0032319 12133 95 36 1 233 2 2 false 0.650251590942715 0.650251590942715 7.3761210037366725E-68 negative_regulation_of_phosphate_metabolic_process GO:0045936 12133 278 36 1 2776 10 3 false 0.6525083708176205 0.6525083708176205 0.0 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 36 2 4239 20 3 false 0.6529352382692473 0.6529352382692473 0.0 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 36 8 307 12 1 false 0.6551180774128461 0.6551180774128461 1.4733469150792184E-83 negative_regulation_of_gene_expression GO:0010629 12133 817 36 6 3906 31 3 false 0.6552325374211485 0.6552325374211485 0.0 U12-type_spliceosomal_complex GO:0005689 12133 24 36 1 150 6 1 false 0.6555111893932324 0.6555111893932324 2.5760759444825708E-28 regulation_of_hydrolase_activity GO:0051336 12133 821 36 3 3094 12 2 false 0.6557911990242847 0.6557911990242847 0.0 histone_H4-K16_acetylation GO:0043984 12133 18 36 1 44 2 1 false 0.6564482029598254 0.6564482029598254 9.7131635117721E-13 rRNA_metabolic_process GO:0016072 12133 107 36 1 258 2 1 false 0.6584019545741964 0.6584019545741964 1.860360860420455E-75 androgen_receptor_signaling_pathway GO:0030521 12133 62 36 2 102 3 1 false 0.6608037274315484 0.6608037274315484 2.6706454874295595E-29 phagocytosis GO:0006909 12133 149 36 1 2417 17 2 false 0.662234112465941 0.662234112465941 3.130675140672653E-242 GTPase_activity GO:0003924 12133 612 36 4 1061 7 2 false 0.6645657671630962 0.6645657671630962 4.702100395E-313 actin_cytoskeleton_organization GO:0030036 12133 373 36 2 768 4 2 false 0.6661741392198718 0.6661741392198718 3.0657297438498186E-230 mRNA_stabilization GO:0048255 12133 22 36 1 33 1 2 false 0.6666666666666647 0.6666666666666647 5.166978132108427E-9 PML_body_organization GO:0030578 12133 4 36 1 6 1 1 false 0.6666666666666662 0.6666666666666662 0.06666666666666664 ferric_iron_transport GO:0015682 12133 24 36 1 36 1 2 false 0.6666666666666695 0.6666666666666695 7.989277111831545E-10 response_to_hormone_stimulus GO:0009725 12133 611 36 2 1784 6 2 false 0.667052487103675 0.667052487103675 0.0 androgen_receptor_binding GO:0050681 12133 38 36 2 62 3 1 false 0.6691697514542756 0.6691697514542756 1.0311688046013243E-17 mitochondrial_membrane GO:0031966 12133 359 36 1 1810 5 3 false 0.6693645417065379 0.6693645417065379 0.0 protein_phosphorylation GO:0006468 12133 1195 36 4 2577 9 2 false 0.6700784084442594 0.6700784084442594 0.0 cell_cycle_phase GO:0022403 12133 253 36 2 953 8 1 false 0.6713323700130274 0.6713323700130274 1.0384727319913012E-238 Fc_receptor_mediated_stimulatory_signaling_pathway GO:0002431 12133 76 36 1 178 2 1 false 0.6730146638735872 0.6730146638735872 2.9073989409378337E-52 intracellular_protein_kinase_cascade GO:0007243 12133 806 36 3 1813 7 1 false 0.6732732537705011 0.6732732537705011 0.0 steroid_metabolic_process GO:0008202 12133 182 36 1 5438 33 2 false 0.6759089994893156 0.6759089994893156 0.0 peptidase_activity GO:0008233 12133 614 36 2 2556 9 1 false 0.6760046231012817 0.6760046231012817 0.0 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 36 1 5033 18 3 false 0.6772996764921855 0.6772996764921855 0.0 cell_projection GO:0042995 12133 976 36 3 9983 35 1 false 0.6788912400011089 0.6788912400011089 0.0 organelle_assembly GO:0070925 12133 210 36 1 2677 14 2 false 0.6822908036533111 0.6822908036533111 7.5039E-319 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 36 3 185 3 1 false 0.6824767390341715 0.6824767390341715 5.464989090238489E-29 keratinocyte_differentiation GO:0030216 12133 69 36 1 101 1 1 false 0.6831683168316771 0.6831683168316771 4.776983203472662E-27 positive_regulation_of_organelle_organization GO:0010638 12133 217 36 1 2191 11 3 false 0.6833715161975031 0.6833715161975031 1.6765812392172608E-306 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 36 6 5558 33 3 false 0.6848117951408774 0.6848117951408774 0.0 mitotic_cell_cycle GO:0000278 12133 625 36 5 1295 11 1 false 0.6858512291804721 0.6858512291804721 0.0 cyclic_nucleotide_metabolic_process GO:0009187 12133 177 36 1 1317 8 1 false 0.6858673133136233 0.6858673133136233 5.758082552903037E-225 response_to_light_stimulus GO:0009416 12133 201 36 1 293 1 1 false 0.6860068259385791 0.6860068259385791 1.3130246435910127E-78 Golgi_membrane GO:0000139 12133 322 36 1 1835 6 3 false 0.6863394180544921 0.6863394180544921 0.0 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 36 17 6094 34 2 false 0.6868313177471469 0.6868313177471469 0.0 cellular_protein_complex_disassembly GO:0043624 12133 149 36 11 154 11 1 false 0.68685076214748 0.68685076214748 1.4793035521715585E-9 GTP_metabolic_process GO:0046039 12133 625 36 4 1193 8 3 false 0.6881945820549406 0.6881945820549406 0.0 regulation_of_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0032434 12133 57 36 1 227 4 2 false 0.6882571179811336 0.6882571179811336 4.5524072103258975E-55 rRNA_processing GO:0006364 12133 102 36 1 231 2 3 false 0.6892151326932874 0.6892151326932874 2.6685808966337758E-68 S-adenosylmethionine-dependent_methyltransferase_activity GO:0008757 12133 87 36 1 126 1 1 false 0.6904761904761948 0.6904761904761948 1.8124217932719872E-33 signal_transducer_activity GO:0004871 12133 1070 36 3 3547 11 2 false 0.6918802673784386 0.6918802673784386 0.0 regulation_of_cell_motility GO:2000145 12133 370 36 1 831 2 3 false 0.692546358720042 0.692546358720042 3.695619588048616E-247 ncRNA_metabolic_process GO:0034660 12133 258 36 2 3294 30 1 false 0.6940893189830273 0.6940893189830273 0.0 regulation_of_nucleocytoplasmic_transport GO:0046822 12133 147 36 1 450 3 2 false 0.695715942835703 0.695715942835703 8.40005869125793E-123 membrane-bounded_vesicle GO:0031988 12133 762 36 4 834 4 1 false 0.6964013336847047 0.6964013336847047 6.820230733401612E-106 tissue_development GO:0009888 12133 1132 36 3 3099 9 1 false 0.6976479176653015 0.6976479176653015 0.0 negative_regulation_of_cell_proliferation GO:0008285 12133 455 36 2 2949 15 3 false 0.6981726127258174 0.6981726127258174 0.0 cell_differentiation GO:0030154 12133 2154 36 7 2267 7 1 false 0.6987917792378382 0.6987917792378382 2.602261335719434E-194 nucleoplasm_part GO:0044451 12133 805 36 6 2767 23 2 false 0.7000595706587464 0.7000595706587464 0.0 behavior GO:0007610 12133 429 36 1 5200 14 1 false 0.700911034968332 0.700911034968332 0.0 binding GO:0005488 12133 8962 36 31 10257 36 1 false 0.7011138028554532 0.7011138028554532 0.0 coated_vesicle_membrane GO:0030662 12133 122 36 1 368 3 2 false 0.7024937803577667 0.7024937803577667 6.74679218492705E-101 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 36 3 803 4 1 false 0.7039167912703328 0.7039167912703328 1.0286714317927864E-202 Golgi_vesicle_transport GO:0048193 12133 170 36 1 2599 18 3 false 0.7052970068236519 0.7052970068236519 6.28157499519694E-272 neuron_projection GO:0043005 12133 534 36 2 1043 4 2 false 0.7056350000579622 0.7056350000579622 5.7946905775E-313 regulation_of_locomotion GO:0040012 12133 398 36 1 6714 20 2 false 0.7059374758146348 0.7059374758146348 0.0 protein_phosphorylated_amino_acid_binding GO:0045309 12133 19 36 1 42 2 1 false 0.7061556329849084 0.7061556329849084 2.238261550776809E-12 extracellular_region_part GO:0044421 12133 740 36 2 10701 35 2 false 0.7073526179538066 0.7073526179538066 0.0 mitochondrion_organization GO:0007005 12133 215 36 1 2031 11 1 false 0.7088829521991253 0.7088829521991253 4.082912305313268E-297 adenylate_cyclase_activity GO:0004016 12133 103 36 1 145 1 3 false 0.710344827586197 0.710344827586197 1.7288474062512548E-37 DNA_integrity_checkpoint GO:0031570 12133 130 36 2 202 3 1 false 0.7104182059996653 0.7104182059996653 1.23666756413938E-56 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 36 4 6622 20 1 false 0.7136835936460069 0.7136835936460069 0.0 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 36 4 1053 7 1 false 0.7148034849213847 0.7148034849213847 1.6418245301060377E-306 vasculature_development GO:0001944 12133 441 36 1 2686 7 2 false 0.7154856444759701 0.7154856444759701 0.0 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 36 2 5027 26 3 false 0.7162016762666997 0.7162016762666997 0.0 enzyme_inhibitor_activity GO:0004857 12133 240 36 1 1075 5 2 false 0.7180155539129013 0.7180155539129013 4.258934911432728E-247 hemostasis GO:0007599 12133 447 36 2 527 2 1 false 0.7191939452097564 0.7191939452097564 7.174896528140087E-97 neuronal_cell_body GO:0043025 12133 215 36 1 621 3 2 false 0.7212669396188487 0.7212669396188487 3.1563152846547707E-173 endosomal_part GO:0044440 12133 257 36 1 7185 35 3 false 0.7213877368558125 0.7213877368558125 0.0 chromatin_modification GO:0016568 12133 458 36 2 539 2 1 false 0.7217896283219056 0.7217896283219056 1.802023694196357E-98 proteolysis GO:0006508 12133 732 36 4 3431 22 1 false 0.7221845194690196 0.7221845194690196 0.0 membrane_invagination GO:0010324 12133 411 36 2 784 4 1 false 0.723465363137763 0.723465363137763 8.658368437912315E-235 spindle GO:0005819 12133 221 36 1 4762 27 4 false 0.7238067025479636 0.7238067025479636 0.0 blood_vessel_development GO:0001568 12133 420 36 1 3152 9 3 false 0.7243954743999286 0.7243954743999286 0.0 protein_complex_biogenesis GO:0070271 12133 746 36 4 1525 9 1 false 0.7249553761186847 0.7249553761186847 0.0 transport GO:0006810 12133 2783 36 18 2833 18 1 false 0.7250637983225824 0.7250637983225824 1.147202604491021E-108 organelle_membrane GO:0031090 12133 1619 36 5 9319 34 3 false 0.7278834311387765 0.7278834311387765 0.0 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 36 2 381 4 2 false 0.7287467416803275 0.7287467416803275 8.855041133991382E-114 cell_activation GO:0001775 12133 656 36 2 7541 29 1 false 0.7318435241649199 0.7318435241649199 0.0 regulation_of_cellular_component_movement GO:0051270 12133 412 36 1 6475 20 3 false 0.732028795810434 0.732028795810434 0.0 mitochondrion GO:0005739 12133 1138 36 4 8213 35 2 false 0.7342777538433631 0.7342777538433631 0.0 acid-amino_acid_ligase_activity GO:0016881 12133 351 36 4 379 4 1 false 0.7347162184919973 0.7347162184919973 5.324332733169013E-43 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 36 1 2035 8 3 false 0.7365598571237069 0.7365598571237069 0.0 coated_vesicle GO:0030135 12133 202 36 1 712 4 1 false 0.7376352700755602 0.7376352700755602 1.1363731817938802E-183 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 36 1 129 2 1 false 0.7401889534883652 0.7401889534883652 2.169508265339551E-38 molecular_transducer_activity GO:0060089 12133 1070 36 3 10257 36 1 false 0.7401974186547721 0.7401974186547721 0.0 interaction_with_host GO:0051701 12133 387 36 4 417 4 2 false 0.7409900906291358 0.7409900906291358 1.9217516081652173E-46 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 36 6 4582 27 3 false 0.741913661728411 0.741913661728411 0.0 Ras_protein_signal_transduction GO:0007265 12133 365 36 2 547 3 1 false 0.7419619945323741 0.7419619945323741 2.1494674666292624E-150 identical_protein_binding GO:0042802 12133 743 36 2 6397 22 1 false 0.7432264190184306 0.7432264190184306 0.0 membrane_organization GO:0061024 12133 787 36 4 3745 23 1 false 0.7438582091395476 0.7438582091395476 0.0 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 36 6 5151 33 4 false 0.744093485409389 0.744093485409389 0.0 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 36 1 5157 15 3 false 0.7446531653680901 0.7446531653680901 0.0 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 36 4 2780 10 2 false 0.74492690239794 0.74492690239794 0.0 protein_folding GO:0006457 12133 183 36 1 3038 22 1 false 0.746325675717086 0.746325675717086 1.582632936584301E-299 regulation_of_adenylate_cyclase_activity GO:0045761 12133 103 36 1 138 1 4 false 0.7463768115942113 0.7463768115942113 1.4792034822830027E-33 N-acetyltransferase_activity GO:0008080 12133 68 36 1 91 1 2 false 0.747252747252751 0.747252747252751 4.74214851415134E-22 epithelial_cell_differentiation GO:0030855 12133 397 36 1 2228 7 2 false 0.7473480577619788 0.7473480577619788 0.0 DNA_recombination GO:0006310 12133 190 36 1 791 5 1 false 0.7477991580760719 0.7477991580760719 1.2250789605162758E-188 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 36 1 129 2 1 false 0.7480620155038853 0.7480620155038853 2.1037655906323275E-38 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 36 1 1631 10 2 false 0.7490293383221256 0.7490293383221256 3.3133814045702313E-271 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 36 2 1399 6 3 false 0.7495259332533957 0.7495259332533957 0.0 metal_ion_transport GO:0030001 12133 455 36 1 606 1 1 false 0.7508250825082763 0.7508250825082763 4.665536224038032E-147 negative_regulation_of_apoptotic_process GO:0043066 12133 537 36 2 1377 6 3 false 0.7513688406830015 0.7513688406830015 0.0 regulation_of_Ras_GTPase_activity GO:0032318 12133 179 36 1 357 2 2 false 0.7521008403362168 0.7521008403362168 8.083441090582102E-107 response_to_biotic_stimulus GO:0009607 12133 494 36 1 5200 14 1 false 0.7532365426348664 0.7532365426348664 0.0 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 36 6 4456 27 4 false 0.7542956368346947 0.7542956368346947 0.0 double-strand_break_repair GO:0006302 12133 109 36 1 368 4 1 false 0.7563285060808744 0.7563285060808744 1.714085470943145E-96 transcription_cofactor_activity GO:0003712 12133 456 36 5 482 5 2 false 0.7569583202776928 0.7569583202776928 1.3948726648763881E-43 axonogenesis GO:0007409 12133 421 36 2 483 2 2 false 0.7595165073066241 0.7595165073066241 7.423880338325494E-80 regulation_of_protein_localization GO:0032880 12133 349 36 2 2148 16 2 false 0.7605729786763963 0.7605729786763963 0.0 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 36 3 10311 36 3 false 0.7617641440644721 0.7617641440644721 0.0 negative_regulation_of_cell_death GO:0060548 12133 567 36 2 3054 14 3 false 0.7642406130234449 0.7642406130234449 0.0 enzyme_regulator_activity GO:0030234 12133 771 36 2 10257 36 3 false 0.7649105598962922 0.7649105598962922 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 36 3 165 3 2 false 0.7651367785290062 0.7651367785290062 1.3866478491946915E-20 microtubule_organizing_center GO:0005815 12133 413 36 1 1076 3 2 false 0.7664671602366018 0.7664671602366018 2.6476518998275E-310 regulation_of_biological_quality GO:0065008 12133 2082 36 5 6908 20 1 false 0.7669805132352623 0.7669805132352623 0.0 dendrite GO:0030425 12133 276 36 1 534 2 1 false 0.7670383877567091 0.7670383877567091 6.975042602902724E-160 JNK_cascade GO:0007254 12133 159 36 1 207 1 1 false 0.7681159420289673 0.7681159420289673 3.1556682987155503E-48 mRNA_export_from_nucleus GO:0006406 12133 60 36 1 116 2 2 false 0.7691154422788684 0.7691154422788684 1.7435958103584361E-34 toll-like_receptor_signaling_pathway GO:0002224 12133 129 36 2 147 2 1 false 0.7693597987139774 0.7693597987139774 1.843896992838607E-23 system_development GO:0048731 12133 2686 36 7 3304 9 2 false 0.7720165288498992 0.7720165288498992 0.0 mRNA_processing GO:0006397 12133 374 36 10 763 23 2 false 0.7732072867473329 0.7732072867473329 8.270510506831645E-229 multicellular_organismal_signaling GO:0035637 12133 604 36 1 5594 13 2 false 0.7739622657643799 0.7739622657643799 0.0 organ_development GO:0048513 12133 1929 36 5 3099 9 2 false 0.7788294520406793 0.7788294520406793 0.0 transmembrane_transport GO:0055085 12133 728 36 2 7606 29 2 false 0.7805744787043307 0.7805744787043307 0.0 catalytic_activity GO:0003824 12133 4901 36 15 10478 36 2 false 0.7824071401360634 0.7824071401360634 0.0 T_cell_receptor_signaling_pathway GO:0050852 12133 88 36 1 112 1 1 false 0.7857142857143178 0.7857142857143178 5.828412725788921E-25 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 36 2 71 2 3 false 0.785915492957749 0.785915492957749 9.399268641403064E-11 negative_regulation_of_phosphorus_metabolic_process GO:0010563 12133 278 36 1 3568 19 3 false 0.7867520429912422 0.7867520429912422 0.0 GTP_catabolic_process GO:0006184 12133 614 36 4 957 7 4 false 0.786819372405746 0.786819372405746 2.3934835856107606E-270 ribose_phosphate_biosynthetic_process GO:0046390 12133 279 36 1 1586 8 3 false 0.7880971446955637 0.7880971446955637 1.5665E-319 positive_regulation_of_intracellular_transport GO:0032388 12133 126 36 1 1370 16 3 false 0.7883037146157041 0.7883037146157041 5.304932497681123E-182 protein_kinase_binding GO:0019901 12133 341 36 2 384 2 1 false 0.7883213664057611 0.7883213664057611 5.20098898434574E-58 nitrogen_compound_transport GO:0071705 12133 428 36 2 2783 18 1 false 0.7895178850849869 0.7895178850849869 0.0 response_to_oxygen-containing_compound GO:1901700 12133 864 36 2 2369 7 1 false 0.790802035356762 0.790802035356762 0.0 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 36 1 312 1 1 false 0.7916666666666485 0.7916666666666485 8.216510305576978E-69 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 36 1 129 2 1 false 0.7927567829457374 0.7927567829457374 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 36 1 129 2 1 false 0.7927567829457374 0.7927567829457374 3.3394798770258706E-38 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 36 4 956 7 2 false 0.7932681242860686 0.7932681242860686 3.936677708897206E-269 multicellular_organismal_development GO:0007275 12133 3069 36 7 4373 11 2 false 0.793909469255969 0.793909469255969 0.0 viral_genome_replication GO:0019079 12133 55 36 1 557 15 2 false 0.7941312210632505 0.7941312210632505 1.9020892479615726E-77 stress-activated_MAPK_cascade GO:0051403 12133 207 36 1 504 3 2 false 0.7962170064416874 0.7962170064416874 1.7060805667457382E-147 positive_regulation_of_cell_death GO:0010942 12133 383 36 1 3330 13 3 false 0.7963702960520588 0.7963702960520588 0.0 modification-dependent_protein_catabolic_process GO:0019941 12133 378 36 4 400 4 2 false 0.7967935261617423 0.7967935261617423 1.150456419433401E-36 cellular_amino_acid_metabolic_process GO:0006520 12133 337 36 1 7342 34 3 false 0.7983554986145321 0.7983554986145321 0.0 regulation_of_cell_cycle_process GO:0010564 12133 382 36 3 1096 11 2 false 0.7983650302051146 0.7983650302051146 7.137372224746455E-307 protein_import GO:0017038 12133 225 36 1 2509 17 2 false 0.7986309677236092 0.7986309677236092 0.0 nuclear_import GO:0051170 12133 203 36 1 2389 18 3 false 0.7989907798618509 0.7989907798618509 7.452348105569065E-301 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 36 1 129 2 1 false 0.7997819767441774 0.7997819767441774 4.0186961232005657E-38 spindle_assembly_checkpoint GO:0071173 12133 36 36 1 45 1 1 false 0.8000000000000007 0.8000000000000007 1.1284603934692157E-9 regulation_of_cAMP_biosynthetic_process GO:0030817 12133 124 36 1 155 1 4 false 0.8000000000000121 0.8000000000000121 2.5860077232155615E-33 nuclear_division GO:0000280 12133 326 36 3 351 3 1 false 0.8006549324604972 0.8006549324604972 8.671827254018066E-39 regulation_of_nucleoside_metabolic_process GO:0009118 12133 308 36 1 3785 19 2 false 0.8014392749628216 0.8014392749628216 0.0 translation_elongation_factor_activity GO:0003746 12133 22 36 1 180 12 2 false 0.8016750997912543 0.8016750997912543 1.0368938565383413E-28 clathrin-coated_vesicle GO:0030136 12133 162 36 1 202 1 1 false 0.8019801980198291 0.8019801980198291 3.1333299685548734E-43 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 36 1 361 4 1 false 0.8030227978829908 0.8030227978829908 4.560830022372086E-99 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 36 4 1779 6 1 false 0.8030948784602612 0.8030948784602612 0.0 cell_projection_organization GO:0030030 12133 744 36 2 7663 30 2 false 0.8032162066641333 0.8032162066641333 0.0 regulation_of_translation GO:0006417 12133 210 36 1 3605 27 4 false 0.8033912226923425 0.8033912226923425 0.0 response_to_external_stimulus GO:0009605 12133 1046 36 2 5200 14 1 false 0.8053418682194543 0.8053418682194543 0.0 cell_cycle_checkpoint GO:0000075 12133 202 36 3 217 3 1 false 0.8057966872670375 0.8057966872670375 1.925703524045096E-23 neuron_differentiation GO:0030182 12133 812 36 2 2154 7 2 false 0.8096689062625557 0.8096689062625557 0.0 positive_regulation_of_gene_expression GO:0010628 12133 1008 36 6 4103 31 3 false 0.8101274069799881 0.8101274069799881 0.0 cellular_developmental_process GO:0048869 12133 2267 36 7 7817 30 2 false 0.8107206368125839 0.8107206368125839 0.0 regulation_of_GTPase_activity GO:0043087 12133 277 36 1 1145 6 3 false 0.810999471260497 0.810999471260497 2.6919247726004267E-274 regulation_of_cellular_catabolic_process GO:0031329 12133 494 36 2 5000 30 3 false 0.8116443515342435 0.8116443515342435 0.0 PML_body GO:0016605 12133 77 36 1 272 5 1 false 0.8133881522239628 0.8133881522239628 7.662735942565743E-70 ribosome_biogenesis GO:0042254 12133 144 36 2 243 4 1 false 0.8140687651060021 0.8140687651060021 8.984879194471426E-71 protein_acetylation GO:0006473 12133 140 36 2 155 2 1 false 0.815249266862172 0.815249266862172 3.675799410957308E-21 transmission_of_nerve_impulse GO:0019226 12133 586 36 1 4105 11 3 false 0.8166856803193866 0.8166856803193866 0.0 regulation_of_biosynthetic_process GO:0009889 12133 3012 36 14 5483 29 2 false 0.8186302021515472 0.8186302021515472 0.0 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 36 8 207 8 1 false 0.8195162005853682 0.8195162005853682 3.3148479610294504E-10 system_process GO:0003008 12133 1272 36 2 4095 9 1 false 0.82253120955128 0.82253120955128 0.0 regulation_of_cell_development GO:0060284 12133 446 36 1 1519 5 2 false 0.8246044782232831 0.8246044782232831 0.0 neurogenesis GO:0022008 12133 940 36 2 2425 7 2 false 0.8250033625628421 0.8250033625628421 0.0 positive_regulation_of_mitochondrial_membrane_permeability GO:0035794 12133 38 36 1 46 1 1 false 0.8260869565217287 0.8260869565217287 3.832404138206993E-9 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 36 1 129 2 1 false 0.82667151162791 0.82667151162791 1.1512773005265922E-37 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 36 4 5183 22 2 false 0.8286447549355465 0.8286447549355465 0.0 small_conjugating_protein_ligase_activity GO:0019787 12133 335 36 4 351 4 1 false 0.8290748849786549 0.8290748849786549 5.577217121688537E-28 cell_projection_part GO:0044463 12133 491 36 1 9983 35 2 false 0.8293756840341495 0.8293756840341495 0.0 positive_regulation_of_protein_transport GO:0051222 12133 154 36 1 1301 14 3 false 0.8302159891737143 0.8302159891737143 9.736449433094532E-205 nucleoside_binding GO:0001882 12133 1639 36 8 4455 27 3 false 0.834733384247028 0.834733384247028 0.0 internal_protein_amino_acid_acetylation GO:0006475 12133 128 36 2 140 2 1 false 0.8353545734840204 0.8353545734840204 1.3721041217101573E-17 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 36 5 3547 11 1 false 0.838275746997637 0.838275746997637 0.0 signaling GO:0023052 12133 3878 36 11 10446 36 1 false 0.8388431339109339 0.8388431339109339 0.0 regulation_of_cytoskeleton_organization GO:0051493 12133 250 36 1 955 6 2 false 0.8390523819440467 0.8390523819440467 1.2229840665192896E-237 antigen_processing_and_presentation_of_peptide_or_polysaccharide_antigen_via_MHC_class_II GO:0002504 12133 84 36 1 185 3 1 false 0.8394848875961163 0.8394848875961163 7.577866882274746E-55 transferase_activity,_transferring_acyl_groups_other_than_amino-acyl_groups GO:0016747 12133 131 36 1 156 1 1 false 0.8397435897435931 0.8397435897435931 1.7588456795479544E-29 positive_regulation_of_apoptotic_process GO:0043065 12133 362 36 1 1377 6 3 false 0.8402282357528025 0.8402282357528025 0.0 response_to_decreased_oxygen_levels GO:0036293 12133 202 36 3 214 3 1 false 0.8403267426814965 0.8403267426814965 7.108512362452622E-20 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 36 8 1218 8 2 false 0.8410330487042414 0.8410330487042414 3.12960829510125E-54 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 36 1 1393 6 3 false 0.8418925728287574 0.8418925728287574 0.0 large_ribosomal_subunit GO:0015934 12133 73 36 5 132 11 1 false 0.8419180178536552 0.8419180178536552 5.5437540818743186E-39 purine-containing_compound_biosynthetic_process GO:0072522 12133 280 36 1 4251 27 6 false 0.8420579715675136 0.8420579715675136 0.0 nucleic_acid_transport GO:0050657 12133 124 36 2 135 2 1 false 0.8431177446102683 0.8431177446102683 2.2345648964967124E-16 organophosphate_catabolic_process GO:0046434 12133 1000 36 7 2495 22 2 false 0.8445009061830068 0.8445009061830068 0.0 phosphorylation GO:0016310 12133 1421 36 4 2776 10 1 false 0.8473748835620457 0.8473748835620457 0.0 interphase GO:0051325 12133 233 36 2 253 2 1 false 0.8478574565529252 0.8478574565529252 4.555981744751407E-30 positive_regulation_of_intracellular_protein_transport GO:0090316 12133 92 36 1 737 14 4 false 0.848105888828306 0.848105888828306 7.301092489476398E-120 negative_regulation_of_signal_transduction GO:0009968 12133 571 36 1 3588 11 5 false 0.8518543237845229 0.8518543237845229 0.0 mitochondrial_envelope GO:0005740 12133 378 36 1 803 3 2 false 0.8522346099993633 0.8522346099993633 2.632819629334664E-240 purine_nucleotide_biosynthetic_process GO:0006164 12133 269 36 1 1265 8 3 false 0.8531944220704417 0.8531944220704417 1.9379490968147627E-283 striated_muscle_cell_differentiation GO:0051146 12133 203 36 2 267 3 1 false 0.8562511855215267 0.8562511855215267 2.4098375851666058E-63 regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030802 12133 143 36 1 167 1 3 false 0.856287425149713 0.856287425149713 1.5904574919997758E-29 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 36 1 129 2 1 false 0.8575581395348872 0.8575581395348872 8.751505837166389E-37 single-organism_metabolic_process GO:0044710 12133 2877 36 10 8027 35 1 false 0.8596862719134837 0.8596862719134837 0.0 protein_localization_to_mitochondrion GO:0070585 12133 67 36 1 516 14 1 false 0.861099050642175 0.861099050642175 5.765661430685337E-86 purine_ribonucleotide_biosynthetic_process GO:0009152 12133 265 36 1 1206 8 3 false 0.8635148312000556 0.8635148312000556 5.7559641067065754E-275 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 36 1 178 2 1 false 0.8638354599124478 0.8638354599124478 1.7238002808689451E-50 ribonucleotide_biosynthetic_process GO:0009260 12133 275 36 1 1250 8 3 false 0.8638554115813852 0.8638554115813852 3.3374763917028038E-285 regulation_of_cellular_process GO:0050794 12133 6304 36 20 9757 35 2 false 0.8643319406436725 0.8643319406436725 0.0 endosome GO:0005768 12133 455 36 1 8213 35 2 false 0.8645348057977806 0.8645348057977806 0.0 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 36 2 1211 8 2 false 0.8656708584987136 0.8656708584987136 0.0 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 36 1 3447 9 2 false 0.8676998256870573 0.8676998256870573 0.0 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 36 7 2517 22 2 false 0.8677696108496346 0.8677696108496346 0.0 Golgi_apparatus_part GO:0044431 12133 406 36 1 7185 35 3 false 0.8700731001493309 0.8700731001493309 0.0 nucleoside-triphosphatase_activity GO:0017111 12133 1059 36 7 1080 7 1 false 0.8712389716600517 0.8712389716600517 1.2343281293318376E-44 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 36 1 971 23 2 false 0.871740694911223 0.871740694911223 1.7939571902377886E-121 ATP_binding GO:0005524 12133 1212 36 5 1638 8 3 false 0.8723082095348472 0.8723082095348472 0.0 single_organism_reproductive_process GO:0044702 12133 539 36 1 8107 30 2 false 0.8735366556465988 0.8735366556465988 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 36 4 1180 16 1 false 0.8737393794655725 0.8737393794655725 0.0 developmental_process_involved_in_reproduction GO:0003006 12133 340 36 1 3959 23 2 false 0.8739760552294857 0.8739760552294857 0.0 regulation_of_biological_process GO:0050789 12133 6622 36 20 10446 36 2 false 0.8744011892985067 0.8744011892985067 0.0 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 36 3 1546 10 3 false 0.8756402634863047 0.8756402634863047 0.0 cellular_response_to_stimulus GO:0051716 12133 4236 36 13 7871 29 2 false 0.8767556509743548 0.8767556509743548 0.0 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_II GO:0002495 12133 83 36 1 164 3 2 false 0.8817896154421585 0.8817896154421585 6.958070805209033E-49 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 36 7 1072 7 2 false 0.8820251377777801 0.8820251377777801 3.811291228230986E-41 generation_of_neurons GO:0048699 12133 883 36 2 940 2 1 false 0.8823397457674041 0.8823397457674041 7.799501535546468E-93 nuclear_transport GO:0051169 12133 331 36 3 1148 16 1 false 0.8840220873742609 0.8840220873742609 1.3196682196913852E-298 adenyl_ribonucleotide_binding GO:0032559 12133 1231 36 5 1645 8 2 false 0.8843859840683908 0.8843859840683908 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 36 5 1650 8 1 false 0.884603351862392 0.884603351862392 0.0 developmental_process GO:0032502 12133 3447 36 9 10446 36 1 false 0.8870995897708046 0.8870995897708046 0.0 glycosyl_compound_catabolic_process GO:1901658 12133 956 36 7 2175 21 2 false 0.887330700030116 0.887330700030116 0.0 locomotion GO:0040011 12133 1045 36 2 10446 36 1 false 0.8879115252377451 0.8879115252377451 0.0 regulation_of_localization GO:0032879 12133 1242 36 3 7621 30 2 false 0.8882324063448974 0.8882324063448974 0.0 nucleoside_phosphate_biosynthetic_process GO:1901293 12133 323 36 1 4156 27 3 false 0.8882612144059359 0.8882612144059359 0.0 intrinsic_to_membrane GO:0031224 12133 2375 36 2 2995 3 1 false 0.8892774043792759 0.8892774043792759 0.0 cell_proliferation GO:0008283 12133 1316 36 3 8052 30 1 false 0.8894383028592845 0.8894383028592845 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_II GO:0019886 12133 80 36 1 154 3 2 false 0.8913996220497111 0.8913996220497111 7.662175327238918E-46 negative_regulation_of_signaling GO:0023057 12133 597 36 1 4884 17 3 false 0.8914237320470845 0.8914237320470845 0.0 regulation_of_mRNA_stability GO:0043488 12133 33 36 1 37 1 1 false 0.8918918918918968 0.8918918918918968 1.5141191611779804E-5 anatomical_structure_morphogenesis GO:0009653 12133 1664 36 3 3447 9 2 false 0.8922691715034505 0.8922691715034505 0.0 lipid_biosynthetic_process GO:0008610 12133 360 36 1 4386 26 2 false 0.8928371054731775 0.8928371054731775 0.0 negative_regulation_of_cell_communication GO:0010648 12133 599 36 1 4860 17 3 false 0.8935447941381585 0.8935447941381585 0.0 cell_morphogenesis GO:0000902 12133 766 36 2 810 2 1 false 0.8942452959754951 0.8942452959754951 9.285456073507826E-74 nucleotide_biosynthetic_process GO:0009165 12133 322 36 1 1318 8 2 false 0.8943777488341934 0.8943777488341934 2.1862113E-317 internal_peptidyl-lysine_acetylation GO:0018393 12133 124 36 2 131 2 2 false 0.8955960070463914 0.8955960070463914 8.960493506706349E-12 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 36 1 5830 18 3 false 0.8956871697844259 0.8956871697844259 0.0 positive_regulation_of_transport GO:0051050 12133 413 36 1 4769 25 3 false 0.8967442740906602 0.8967442740906602 0.0 response_to_radiation GO:0009314 12133 293 36 1 676 4 1 false 0.8976600313401037 0.8976600313401037 4.1946042901139895E-200 regulation_of_GTP_catabolic_process GO:0033124 12133 279 36 1 642 4 3 false 0.8985268812488418 0.8985268812488418 4.2701237450964594E-190 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 36 7 2643 22 2 false 0.8992622799174974 0.8992622799174974 0.0 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 36 5 3972 27 4 false 0.9010464436441263 0.9010464436441263 0.0 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 36 10 2805 10 1 false 0.901141542748375 0.901141542748375 1.0460685646312495E-69 zinc_ion_binding GO:0008270 12133 1314 36 1 1457 1 1 false 0.9018531228546426 0.9018531228546426 2.194714234876188E-202 'de_novo'_posttranslational_protein_folding GO:0051084 12133 46 36 1 51 1 1 false 0.9019607843137332 0.9019607843137332 4.2570219577192243E-7 transition_metal_ion_binding GO:0046914 12133 1457 36 1 2699 3 1 false 0.9026828714416941 0.9026828714416941 0.0 extracellular_region GO:0005576 12133 1152 36 2 10701 35 1 false 0.9034217502726182 0.9034217502726182 0.0 embryo_development GO:0009790 12133 768 36 1 3347 9 3 false 0.9045519825845856 0.9045519825845856 0.0 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 36 16 5532 34 4 false 0.9055065411410697 0.9055065411410697 0.0 transcription_corepressor_activity GO:0003714 12133 180 36 1 479 5 2 false 0.9064216728351739 0.9064216728351739 5.2319775680795235E-137 regulation_of_protein_transport GO:0051223 12133 261 36 1 1665 14 3 false 0.9090293213039854 0.9090293213039854 3.65102727546E-313 repressing_transcription_factor_binding GO:0070491 12133 207 36 1 715 7 1 false 0.90970413899286 0.90970413899286 4.3536836236667346E-186 structural_constituent_of_cytoskeleton GO:0005200 12133 88 36 1 526 13 1 false 0.91021999531107 0.91021999531107 1.4915391741340796E-102 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 36 2 614 2 1 false 0.910803385921994 0.910803385921994 4.862693095923331E-49 epithelium_development GO:0060429 12133 627 36 1 1132 3 1 false 0.9115083232271376 0.9115083232271376 0.0 cell_development GO:0048468 12133 1255 36 2 3306 9 4 false 0.9117149035833798 0.9117149035833798 0.0 purine_ribonucleotide_binding GO:0032555 12133 1641 36 8 1660 8 2 false 0.9118404836621758 0.9118404836621758 8.870449707822982E-45 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 36 12 3120 17 4 false 0.9140127844048814 0.9140127844048814 0.0 centrosome GO:0005813 12133 327 36 1 3226 23 2 false 0.9151664227734608 0.9151664227734608 0.0 regulation_of_nucleotide_catabolic_process GO:0030811 12133 306 36 1 1279 9 3 false 0.9154104977723903 0.9154104977723903 9.116385096369177E-305 cellular_protein_complex_assembly GO:0043623 12133 284 36 1 958 7 2 false 0.9154668208264817 0.9154668208264817 4.57678794545446E-252 cellular_component_movement GO:0006928 12133 1012 36 2 7541 29 1 false 0.9162515281698566 0.9162515281698566 0.0 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 36 15 4544 32 3 false 0.9181262946552377 0.9181262946552377 0.0 protein_processing GO:0016485 12133 113 36 1 123 1 1 false 0.918699186991829 0.918699186991829 6.665856545071852E-15 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I,_TAP-dependent GO:0002479 12133 70 36 2 73 2 1 false 0.9189497716895059 0.9189497716895059 1.607820438613435E-5 RNA_3'-end_processing GO:0031123 12133 98 36 1 601 14 1 false 0.9197060387186737 0.9197060387186737 1.9130441150898719E-115 small_GTPase_binding GO:0031267 12133 126 36 1 137 1 1 false 0.9197080291970834 0.9197080291970834 1.8889221296599312E-16 positive_regulation_of_cell_proliferation GO:0008284 12133 558 36 1 3155 13 3 false 0.9207809045768569 0.9207809045768569 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 36 10 7256 35 1 false 0.922112806250014 0.922112806250014 0.0 mRNA_3'-end_processing GO:0031124 12133 86 36 1 386 10 2 false 0.9222773952358562 0.9222773952358562 2.4694341980396157E-88 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 36 2 78 2 1 false 0.9240759240759076 0.9240759240759076 1.3144749986854762E-5 immune_effector_process GO:0002252 12133 445 36 1 1618 8 1 false 0.9241956295935508 0.9241956295935508 0.0 ribonucleoside_metabolic_process GO:0009119 12133 1071 36 7 1083 7 1 false 0.9247670829177739 0.9247670829177739 1.9559437642804265E-28 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 36 5 3847 31 4 false 0.9261031278571097 0.9261031278571097 0.0 single_organism_signaling GO:0044700 12133 3878 36 11 8052 30 2 false 0.9267943492118722 0.9267943492118722 0.0 regulation_of_purine_nucleotide_catabolic_process GO:0033121 12133 305 36 1 1088 8 3 false 0.9287663414897627 0.9287663414897627 1.7563474810306042E-279 response_to_stimulus GO:0050896 12133 5200 36 14 10446 36 1 false 0.9306179729298942 0.9306179729298942 0.0 chromosome_organization GO:0051276 12133 689 36 2 2031 11 1 false 0.9308445671004366 0.9308445671004366 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 36 14 4972 29 3 false 0.9310839771456526 0.9310839771456526 0.0 cell-cell_signaling GO:0007267 12133 859 36 1 3969 11 2 false 0.9318906731074718 0.9318906731074718 0.0 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 36 7 1014 7 1 false 0.9327823799616627 0.9327823799616627 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 36 7 1014 7 1 false 0.9327823799616627 0.9327823799616627 3.301546202575714E-24 striated_muscle_tissue_development GO:0014706 12133 285 36 2 295 2 1 false 0.9332410930473944 0.9332410930473944 8.482306621073292E-19 biological_regulation GO:0065007 12133 6908 36 20 10446 36 1 false 0.9333086874877572 0.9333086874877572 0.0 single-organism_developmental_process GO:0044767 12133 2776 36 7 8064 30 2 false 0.9338791766018993 0.9338791766018993 0.0 regulation_of_cellular_localization GO:0060341 12133 603 36 1 6869 30 3 false 0.9368677101256053 0.9368677101256053 0.0 metal_ion_binding GO:0046872 12133 2699 36 3 2758 3 1 false 0.9371638657921635 0.9371638657921635 2.6200760259069314E-123 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 36 4 378 4 1 false 0.9377621009462849 0.9377621009462849 2.5686196448553377E-13 regulation_of_intracellular_transport GO:0032386 12133 276 36 1 1731 16 3 false 0.9387217756389797 0.9387217756389797 0.0 mitochondrial_part GO:0044429 12133 557 36 1 7185 35 3 false 0.9410589364250026 0.9410589364250026 0.0 organophosphate_biosynthetic_process GO:0090407 12133 477 36 1 4948 28 2 false 0.941957530007492 0.941957530007492 0.0 protein_dimerization_activity GO:0046983 12133 779 36 1 6397 22 1 false 0.9428338893676728 0.9428338893676728 0.0 nervous_system_development GO:0007399 12133 1371 36 2 2686 7 1 false 0.9442922913179789 0.9442922913179789 0.0 response_to_wounding GO:0009611 12133 905 36 2 2540 11 1 false 0.9446451129585601 0.9446451129585601 0.0 cellular_component_morphogenesis GO:0032989 12133 810 36 2 5068 27 4 false 0.9447479058829158 0.9447479058829158 0.0 Fc-gamma_receptor_signaling_pathway GO:0038094 12133 72 36 1 76 1 1 false 0.9473684210526206 0.9473684210526206 7.79438414622254E-7 regulation_of_intracellular_protein_transport GO:0033157 12133 160 36 1 847 14 3 false 0.9479969263851311 0.9479969263851311 1.5386851760422239E-177 apoptotic_process GO:0006915 12133 1373 36 6 1385 6 1 false 0.9490374804754879 0.9490374804754879 1.0085392941984968E-29 extracellular_space GO:0005615 12133 574 36 1 740 2 1 false 0.9499140547861356 0.9499140547861356 2.3774559423833748E-170 carboxylic_acid_metabolic_process GO:0019752 12133 614 36 1 7453 35 2 false 0.9510188416157582 0.9510188416157582 0.0 macromolecule_modification GO:0043412 12133 2461 36 10 6052 35 1 false 0.9514780801217652 0.9514780801217652 0.0 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 36 3 2528 12 3 false 0.9516270386121057 0.9516270386121057 0.0 Ras_GTPase_binding GO:0017016 12133 120 36 1 126 1 1 false 0.9523809523809658 0.9523809523809658 2.030392220357244E-10 integral_to_membrane GO:0016021 12133 2318 36 2 2375 2 1 false 0.952566133110128 0.952566133110128 3.0839384482043954E-116 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 36 1 4947 28 2 false 0.9571652891854175 0.9571652891854175 0.0 cytoskeletal_part GO:0044430 12133 1031 36 3 5573 33 2 false 0.9586580028660789 0.9586580028660789 0.0 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 36 7 1007 7 2 false 0.9589097326353674 0.9589097326353674 7.008686204750717E-16 localization_of_cell GO:0051674 12133 785 36 2 3467 20 1 false 0.9600354588371138 0.9600354588371138 0.0 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 36 3 1225 4 2 false 0.9610558149612053 0.9610558149612053 5.928244845001387E-155 cell_communication GO:0007154 12133 3962 36 11 7541 29 1 false 0.9615278602099209 0.9615278602099209 0.0 purine_nucleoside_binding GO:0001883 12133 1631 36 8 1639 8 1 false 0.961531589076234 0.961531589076234 7.876250956196666E-22 activation_of_adenylate_cyclase_activity GO:0007190 12133 50 36 1 52 1 1 false 0.9615384615384723 0.9615384615384723 7.54147812971345E-4 organonitrogen_compound_biosynthetic_process GO:1901566 12133 548 36 1 5099 29 2 false 0.9633686882051933 0.9633686882051933 0.0 nucleocytoplasmic_transport GO:0006913 12133 327 36 3 331 3 1 false 0.9640751355092443 0.9640751355092443 2.036102168267257E-9 chromosomal_part GO:0044427 12133 512 36 1 5337 33 2 false 0.9645166224476422 0.9645166224476422 0.0 organic_acid_metabolic_process GO:0006082 12133 676 36 1 7326 35 2 false 0.966517480468972 0.966517480468972 0.0 purine_ribonucleoside_binding GO:0032550 12133 1629 36 8 1635 8 2 false 0.9709550845429742 0.9709550845429742 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 36 8 1639 8 1 false 0.9710252105572678 0.9710252105572678 3.7483303336303164E-17 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 36 28 7976 34 2 false 0.9710437809025144 0.9710437809025144 0.0 ion_transport GO:0006811 12133 833 36 3 2323 17 1 false 0.972514662707182 0.972514662707182 0.0 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 36 2 149 2 1 false 0.9732450571376651 0.9732450571376651 9.06947215672054E-5 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 36 7 1085 7 1 false 0.9744071497386324 0.9744071497386324 1.7413918354446858E-11 viral_reproduction GO:0016032 12133 633 36 16 634 16 1 false 0.974763406940269 0.974763406940269 0.0015772870662463625 membrane-bounded_organelle GO:0043227 12133 7284 36 28 7980 34 1 false 0.9749994697914348 0.9749994697914348 0.0 cell_periphery GO:0071944 12133 2667 36 5 9983 35 1 false 0.9750229740514752 0.9750229740514752 0.0 Golgi_apparatus GO:0005794 12133 828 36 1 8213 35 2 false 0.9759472010330306 0.9759472010330306 0.0 lipid_metabolic_process GO:0006629 12133 769 36 1 7599 35 3 false 0.9763185607409057 0.9763185607409057 0.0 peptide_binding GO:0042277 12133 178 36 1 182 1 1 false 0.9780219780219295 0.9780219780219295 2.2611831618281403E-8 endoplasmic_reticulum GO:0005783 12133 854 36 1 8213 35 2 false 0.9787464136211802 0.9787464136211802 0.0 mRNA_transport GO:0051028 12133 106 36 1 124 2 1 false 0.979937057435057 0.979937057435057 4.872659948511352E-22 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 36 2 199 2 1 false 0.9799502563321717 0.9799502563321717 5.075884472869322E-5 cation_transport GO:0006812 12133 606 36 1 833 3 1 false 0.9799577044093348 0.9799577044093348 4.047492354513465E-211 purine-containing_compound_catabolic_process GO:0072523 12133 959 36 7 1651 19 6 false 0.982572922066468 0.982572922066468 0.0 multicellular_organismal_process GO:0032501 12133 4223 36 9 10446 36 1 false 0.9828121409185714 0.9828121409185714 0.0 macromolecular_complex_assembly GO:0065003 12133 973 36 7 1603 18 2 false 0.9831000851833144 0.9831000851833144 0.0 ion_binding GO:0043167 12133 4448 36 10 8962 31 1 false 0.9838334916690505 0.9838334916690505 0.0 protein_ubiquitination GO:0016567 12133 548 36 3 578 4 1 false 0.9853447186100764 0.9853447186100764 7.913703273197485E-51 oxoacid_metabolic_process GO:0043436 12133 667 36 1 676 1 1 false 0.9866863905329417 0.9866863905329417 1.2985791548492531E-20 regulation_of_gene_expression GO:0010468 12133 2935 36 16 4361 32 2 false 0.986880000080988 0.986880000080988 0.0 chordate_embryonic_development GO:0043009 12133 471 36 1 477 1 1 false 0.9874213836479633 0.9874213836479633 6.308586670641318E-14 plasma_membrane GO:0005886 12133 2594 36 4 10252 35 3 false 0.9877661474198342 0.9877661474198342 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 36 8 1319 8 1 false 0.9879018109318232 0.9879018109318232 1.1504554077729292E-6 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 36 1 1192 15 2 false 0.988675410308884 0.988675410308884 5.168872172755415E-294 nucleoside_catabolic_process GO:0009164 12133 952 36 7 1516 18 5 false 0.9896592971226884 0.9896592971226884 0.0 establishment_of_protein_localization_to_mitochondrion GO:0072655 12133 66 36 1 211 12 2 false 0.9904437494512346 0.9904437494512346 1.9619733177914497E-56 chromosome GO:0005694 12133 592 36 1 3226 23 1 false 0.9907276988820978 0.9907276988820978 0.0 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 36 13 4395 29 3 false 0.9908782726722459 0.9908782726722459 0.0 vesicle-mediated_transport GO:0016192 12133 895 36 2 2783 18 1 false 0.9913271715902993 0.9913271715902993 0.0 cation_binding GO:0043169 12133 2758 36 3 4448 10 1 false 0.9914641961373596 0.9914641961373596 0.0 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 36 7 1587 19 3 false 0.9918141771661667 0.9918141771661667 0.0 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 36 4 672 14 1 false 0.9924525160308239 0.9924525160308239 6.935915883902889E-199 plasma_membrane_part GO:0044459 12133 1329 36 1 10213 35 3 false 0.9924640422235009 0.9924640422235009 0.0 membrane GO:0016020 12133 4398 36 8 10701 35 1 false 0.9928968423658379 0.9928968423658379 0.0 pyrophosphatase_activity GO:0016462 12133 1080 36 7 1081 7 1 false 0.9935245143381188 0.9935245143381188 9.250693802031629E-4 single-multicellular_organism_process GO:0044707 12133 4095 36 9 8057 30 2 false 0.9937973469790048 0.9937973469790048 0.0 ncRNA_processing GO:0034470 12133 186 36 1 649 15 2 false 0.9940938793435569 0.9940938793435569 4.048832162241149E-168 protein_import_into_nucleus GO:0006606 12133 200 36 1 690 15 5 false 0.9944694782607754 0.9944694782607754 1.1794689955817937E-179 purine_nucleotide_binding GO:0017076 12133 1650 36 8 1997 14 1 false 0.9949292345989035 0.9949292345989035 0.0 ribonucleotide_binding GO:0032553 12133 1651 36 8 1997 14 1 false 0.9950138731925976 0.9950138731925976 0.0 extracellular_matrix_organization GO:0030198 12133 200 36 1 201 1 1 false 0.9950248756219159 0.9950248756219159 0.004975124378109382 transcription,_DNA-dependent GO:0006351 12133 2643 36 13 4063 30 3 false 0.9957051839921945 0.9957051839921945 0.0 cell_migration GO:0016477 12133 734 36 1 785 2 1 false 0.9958566229039721 0.9958566229039721 1.8763224028220524E-81 protein_localization_to_nucleus GO:0034504 12133 233 36 2 516 14 1 false 0.9974886096763289 0.9974886096763289 1.4955266190313754E-153 virus-host_interaction GO:0019048 12133 355 36 4 588 15 2 false 0.9984534019649417 0.9984534019649417 1.0104535019427035E-170 protein_modification_process GO:0036211 12133 2370 36 9 3518 23 2 false 0.9986771080919117 0.9986771080919117 0.0 membrane_part GO:0044425 12133 2995 36 3 10701 35 2 false 0.9989476240868761 0.9989476240868761 0.0 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 36 13 3611 26 3 false 0.9991960563903824 0.9991960563903824 0.0 regulation_of_transport GO:0051049 12133 942 36 1 3017 19 2 false 0.9992053390003576 0.9992053390003576 0.0 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 36 3 2849 23 1 false 0.9992889501127944 0.9992889501127944 0.0 protein_targeting_to_nucleus GO:0044744 12133 200 36 1 443 12 1 false 0.9993456075070108 0.9993456075070108 9.352491047681514E-132 response_to_other_organism GO:0051707 12133 475 36 1 1194 16 2 false 0.9997204746604008 0.9997204746604008 0.0 cytoskeleton GO:0005856 12133 1430 36 3 3226 23 1 false 0.9997564208130774 0.9997564208130774 0.0 protein_complex_assembly GO:0006461 12133 743 36 4 1214 18 3 false 0.9998711115998503 0.9998711115998503 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 36 12 3220 26 4 false 0.999968643503905 0.999968643503905 0.0 cellular_protein_modification_process GO:0006464 12133 2370 36 9 3038 22 2 false 0.9999705995394452 0.9999705995394452 0.0 DNA_binding GO:0003677 12133 2091 36 5 2849 23 1 false 0.9999999715483552 0.9999999715483552 0.0 protein_complex GO:0043234 12133 2976 36 10 3462 25 1 false 0.9999999890952305 0.9999999890952305 0.0 GO:0000000 12133 11221 36 36 0 0 0 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 36 1 147 1 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 36 2 87 2 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 36 3 1169 3 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 36 4 417 4 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 36 2 124 2 2 true 1.0 1.0 1.0 MLL1_complex GO:0071339 12133 25 36 1 25 1 1 true 1.0 1.0 1.0