ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min ribonucleoprotein_complex GO:0030529 12133 569 34 18 9264 33 2 false 5.203395918143691E-14 5.203395918143691E-14 0.0 translational_elongation GO:0006414 12133 121 34 10 3388 23 2 false 1.8009223604024364E-9 1.8009223604024364E-9 5.332026529203484E-226 translational_initiation GO:0006413 12133 160 34 9 7667 27 2 false 2.0369639494441813E-9 2.0369639494441813E-9 0.0 ribosomal_subunit GO:0044391 12133 132 34 9 7199 32 4 false 3.4978751790744916E-9 3.4978751790744916E-9 2.5906239763169356E-285 multi-organism_cellular_process GO:0044764 12133 634 34 14 9702 33 2 false 5.759774419234168E-9 5.759774419234168E-9 0.0 cytosolic_part GO:0044445 12133 178 34 9 5117 23 2 false 3.2743586298070324E-8 3.2743586298070324E-8 0.0 mRNA_metabolic_process GO:0016071 12133 573 34 17 3294 26 1 false 6.521912623882829E-8 6.521912623882829E-8 0.0 ribosome GO:0005840 12133 210 34 9 6755 29 3 false 1.3337736284504298E-7 1.3337736284504298E-7 0.0 viral_transcription GO:0019083 12133 145 34 9 2964 21 3 false 2.2317474201197763E-7 2.2317474201197763E-7 1.0927707330622845E-250 macromolecular_complex GO:0032991 12133 3462 34 25 10701 33 1 false 3.810244362791754E-7 3.810244362791754E-7 0.0 macromolecule_catabolic_process GO:0009057 12133 820 34 15 6846 32 2 false 1.0410161099565422E-6 1.0410161099565422E-6 0.0 cellular_macromolecule_catabolic_process GO:0044265 12133 672 34 14 6457 32 3 false 1.2092430602845598E-6 1.2092430602845598E-6 0.0 multi-organism_process GO:0051704 12133 1180 34 15 10446 34 1 false 1.3151295706478492E-6 1.3151295706478492E-6 0.0 cellular_component_disassembly GO:0022411 12133 351 34 9 7663 28 2 false 2.5521395111417573E-6 2.5521395111417573E-6 0.0 RNA_catabolic_process GO:0006401 12133 203 34 9 4368 28 3 false 2.7106099535410753E-6 2.7106099535410753E-6 0.0 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 34 10 1239 13 2 false 2.8889218661325995E-6 2.8889218661325995E-6 4.427655683668096E-244 protein_targeting_to_ER GO:0045047 12133 104 34 9 721 12 3 false 2.9841351137735606E-6 2.9841351137735606E-6 1.514347826459292E-128 protein_complex_disassembly GO:0043241 12133 154 34 9 1031 12 2 false 4.412369324822407E-6 4.412369324822407E-6 4.7545827865276796E-188 translational_termination GO:0006415 12133 92 34 9 513 11 2 false 5.486215327932972E-6 5.486215327932972E-6 3.4634519853301643E-104 protein_targeting GO:0006605 12133 443 34 11 2378 15 2 false 5.564864077530208E-6 5.564864077530208E-6 0.0 RNA_binding GO:0003723 12133 763 34 15 2849 20 1 false 8.870626099027056E-6 8.870626099027056E-6 0.0 structural_constituent_of_ribosome GO:0003735 12133 152 34 9 526 9 1 false 1.1824254045591024E-5 1.1824254045591024E-5 1.18011379183299E-136 cellular_process_involved_in_reproduction GO:0048610 12133 469 34 9 9699 33 2 false 1.824872811791515E-5 1.824872811791515E-5 0.0 reproductive_process GO:0022414 12133 1275 34 14 10446 34 2 false 1.9677178859539367E-5 1.9677178859539367E-5 0.0 cytosolic_ribosome GO:0022626 12133 92 34 9 296 9 2 false 2.04346628581382E-5 2.04346628581382E-5 4.2784789004852985E-79 macromolecular_complex_disassembly GO:0032984 12133 199 34 9 1380 14 2 false 2.371925793756827E-5 2.371925793756827E-5 1.9082717261040364E-246 translation GO:0006412 12133 457 34 11 5433 31 3 false 2.372139512944858E-5 2.372139512944858E-5 0.0 catabolic_process GO:0009056 12133 2164 34 20 8027 32 1 false 2.5874369167667983E-5 2.5874369167667983E-5 0.0 organic_substance_catabolic_process GO:1901575 12133 2054 34 20 7502 32 2 false 3.3028461569225694E-5 3.3028461569225694E-5 0.0 reproduction GO:0000003 12133 1345 34 14 10446 34 1 false 3.629538741801408E-5 3.629538741801408E-5 0.0 structural_molecule_activity GO:0005198 12133 526 34 9 10257 34 1 false 3.794750855258205E-5 3.794750855258205E-5 0.0 organelle_part GO:0044422 12133 5401 34 28 10701 33 2 false 4.0249396107405625E-5 4.0249396107405625E-5 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 34 32 7569 32 2 false 6.840049971431518E-5 6.840049971431518E-5 0.0 cellular_catabolic_process GO:0044248 12133 1972 34 19 7289 32 2 false 1.1800195221235178E-4 1.1800195221235178E-4 0.0 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 34 9 516 12 1 false 1.3387984975134142E-4 1.3387984975134142E-4 8.917305549619806E-119 cytosol GO:0005829 12133 2226 34 19 5117 23 1 false 1.3886729758325967E-4 1.3886729758325967E-4 0.0 Prp19_complex GO:0000974 12133 78 34 4 2976 12 1 false 1.8435170975532946E-4 1.8435170975532946E-4 3.570519754703887E-156 ligase_activity GO:0016874 12133 504 34 7 4901 14 1 false 2.101907103237513E-4 2.101907103237513E-4 0.0 multi-organism_reproductive_process GO:0044703 12133 707 34 14 1275 14 1 false 2.4523213371607355E-4 2.4523213371607355E-4 0.0 CRD-mediated_mRNA_stability_complex GO:0070937 12133 6 34 2 6481 27 2 false 2.4816368952501725E-4 2.4816368952501725E-4 9.738359623180132E-21 cellular_metabolic_process GO:0044237 12133 7256 34 32 10007 33 2 false 3.2866276964013696E-4 3.2866276964013696E-4 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 34 19 10701 33 1 false 3.566364054983514E-4 3.566364054983514E-4 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 34 24 8962 30 1 false 4.189697890835898E-4 4.189697890835898E-4 0.0 RNA_processing GO:0006396 12133 601 34 12 3762 27 2 false 4.2418968510356237E-4 4.2418968510356237E-4 0.0 regulation_of_ligase_activity GO:0051340 12133 98 34 4 2061 9 2 false 5.042441831779919E-4 5.042441831779919E-4 1.6310105681359867E-170 organic_cyclic_compound_binding GO:0097159 12133 4407 34 24 8962 30 1 false 5.149148693178842E-4 5.149148693178842E-4 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 34 27 6846 32 2 false 5.397091157366768E-4 5.397091157366768E-4 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 34 15 5462 29 2 false 6.264568613552006E-4 6.264568613552006E-4 0.0 heterocycle_catabolic_process GO:0046700 12133 1243 34 15 5392 29 2 false 7.051467848754869E-4 7.051467848754869E-4 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 34 15 5388 29 2 false 7.50776911358563E-4 7.50776911358563E-4 0.0 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 34 9 2370 12 1 false 7.541332130911612E-4 7.541332130911612E-4 0.0 cellular_macromolecule_localization GO:0070727 12133 918 34 12 2206 14 2 false 9.027146734206734E-4 9.027146734206734E-4 0.0 protein_localization_to_organelle GO:0033365 12133 516 34 12 914 12 1 false 9.907594959568905E-4 9.907594959568905E-4 5.634955900168089E-271 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 34 15 5528 30 2 false 0.0010268968454533235 0.0010268968454533235 0.0 protein_targeting_to_membrane GO:0006612 12133 145 34 9 443 11 1 false 0.0010306607913712026 0.0010306607913712026 5.648405296311656E-121 nitrogen_compound_metabolic_process GO:0006807 12133 5244 34 29 8027 32 1 false 0.0010704943329061247 0.0010704943329061247 0.0 histone_pre-mRNA_3'end_processing_complex GO:0071204 12133 6 34 2 3020 27 2 false 0.0011296522483506873 0.0011296522483506873 9.537822615543818E-19 positive_regulation_of_ligase_activity GO:0051351 12133 84 34 4 1424 9 3 false 0.001132307032576121 0.001132307032576121 5.130084211911676E-138 macromolecule_metabolic_process GO:0043170 12133 6052 34 32 7451 32 1 false 0.0012682221157970094 0.0012682221157970094 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 34 29 7341 32 5 false 0.0013308435037932278 0.0013308435037932278 0.0 spliceosomal_complex GO:0005681 12133 150 34 6 3020 27 2 false 0.001687337539619956 0.001687337539619956 2.455159410572961E-258 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 34 15 4878 29 5 false 0.00173707029881252 0.00173707029881252 0.0 macromolecular_complex_subunit_organization GO:0043933 12133 1256 34 14 3745 21 1 false 0.0019005518793691742 0.0019005518793691742 0.0 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 34 29 7451 32 1 false 0.00252244668568938 0.00252244668568938 0.0 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 34 21 10446 34 1 false 0.0026105759135784034 0.0026105759135784034 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 34 29 7256 32 1 false 0.002747934428723863 0.002747934428723863 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 34 29 7256 32 1 false 0.0028406034505667303 0.0028406034505667303 0.0 single-organism_transport GO:0044765 12133 2323 34 15 8134 27 2 false 0.002902116589070395 0.002902116589070395 0.0 intracellular_receptor_signaling_pathway GO:0030522 12133 217 34 4 3547 11 1 false 0.003196006306856501 0.003196006306856501 0.0 intracellular_protein_transport GO:0006886 12133 658 34 11 1672 14 3 false 0.0032419159070743637 0.0032419159070743637 0.0 cellular_localization GO:0051641 12133 1845 34 13 7707 26 2 false 0.0034311929444421066 0.0034311929444421066 0.0 nucleus GO:0005634 12133 4764 34 22 7259 24 1 false 0.003597115461790378 0.003597115461790378 0.0 viral_genome_expression GO:0019080 12133 153 34 9 557 14 2 false 0.0039030489261207115 0.0039030489261207115 1.6461772406083414E-141 intracellular_organelle_part GO:0044446 12133 5320 34 27 9083 33 3 false 0.004109113680141975 0.004109113680141975 0.0 nuclear_part GO:0044428 12133 2767 34 19 6936 29 2 false 0.004609944402126897 0.004609944402126897 0.0 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 34 29 7275 32 2 false 0.0049486813676628 0.0049486813676628 0.0 DNA_topoisomerase_binding GO:0044547 12133 1 34 1 1005 5 1 false 0.0049751243781071194 0.0049751243781071194 9.950248756221706E-4 positive_regulation_of_protein_ubiquitination GO:0031398 12133 129 34 5 1097 11 3 false 0.005357919049621002 0.005357919049621002 8.208279871491876E-172 RNA_metabolic_process GO:0016070 12133 3294 34 26 5627 32 2 false 0.005724166926686751 0.005724166926686751 0.0 intracellular_transport GO:0046907 12133 1148 34 12 2815 16 2 false 0.005782163509967742 0.005782163509967742 0.0 neurotrophin_signaling_pathway GO:0038179 12133 253 34 4 2018 7 2 false 0.006204685010094772 0.006204685010094772 0.0 ubiquitin-dependent_endocytosis GO:0070086 12133 1 34 1 2417 15 2 false 0.006206040546148298 0.006206040546148298 4.137360364095159E-4 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 34 9 220 10 2 false 0.006295721792048422 0.006295721792048422 1.3850176335002185E-65 biosynthetic_process GO:0009058 12133 4179 34 24 8027 32 1 false 0.006731060814510013 0.006731060814510013 0.0 establishment_of_protein_localization GO:0045184 12133 1153 34 12 3010 17 2 false 0.006963938373361556 0.006963938373361556 0.0 regulation_of_RNA_stability GO:0043487 12133 37 34 2 2240 8 2 false 0.00698421802304729 0.00698421802304729 2.0388833014238124E-81 metabolic_process GO:0008152 12133 8027 34 32 10446 34 1 false 0.007947845881429685 0.007947845881429685 0.0 viral_reproductive_process GO:0022415 12133 557 34 14 783 14 2 false 0.00810104414654082 0.00810104414654082 1.4346997744229993E-203 macromolecule_localization GO:0033036 12133 1642 34 14 3467 18 1 false 0.008482642006874904 0.008482642006874904 0.0 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 34 4 3020 27 2 false 0.008592096321752132 0.008592096321752132 1.1070924240418437E-179 protein_metabolic_process GO:0019538 12133 3431 34 22 7395 32 2 false 0.008836624427294298 0.008836624427294298 0.0 nuclear_lumen GO:0031981 12133 2490 34 19 3186 19 2 false 0.009111158337040666 0.009111158337040666 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 34 19 7980 30 1 false 0.009355049585406642 0.009355049585406642 0.0 positive_regulation_of_chromosome_organization GO:2001252 12133 49 34 2 847 3 3 false 0.009481883488733338 0.009481883488733338 8.5635846172251E-81 multi-organism_transport GO:0044766 12133 29 34 2 3441 18 2 false 0.009652971838738693 0.009652971838738693 2.716860412473803E-72 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 34 19 7958 30 2 false 0.00968029810592265 0.00968029810592265 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 34 2 3208 12 2 false 0.00970102652165285 0.00970102652165285 7.591030632914061E-95 phosphoprotein_binding GO:0051219 12133 42 34 2 6397 23 1 false 0.009756987673585835 0.009756987673585835 2.265958128878875E-109 establishment_of_localization GO:0051234 12133 2833 34 16 10446 34 2 false 0.01000160228806057 0.01000160228806057 0.0 immune_response-regulating_signaling_pathway GO:0002764 12133 310 34 4 3626 11 2 false 0.010658357951475843 0.010658357951475843 0.0 negative_regulation_of_dephosphorylation GO:0035305 12133 6 34 1 562 1 3 false 0.01067615658362861 0.01067615658362861 2.3471675405869638E-14 photoreceptor_cell_outer_segment_organization GO:0035845 12133 3 34 1 7663 28 3 false 0.010923180033782339 0.010923180033782339 1.3339047370190935E-11 viral_infectious_cycle GO:0019058 12133 213 34 10 557 14 1 false 0.011394277429777968 0.011394277429777968 3.455075709157513E-160 cardiovascular_system_development GO:0072358 12133 655 34 5 2686 7 2 false 0.011418066146335754 0.011418066146335754 0.0 circulatory_system_development GO:0072359 12133 655 34 5 2686 7 1 false 0.011418066146335754 0.011418066146335754 0.0 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 34 5 201 9 3 false 0.011771421469452589 0.011771421469452589 2.854176062301069E-41 mesangial_cell_development GO:0072143 12133 5 34 1 1256 3 2 false 0.01190464121024952 0.01190464121024952 3.869857243416382E-14 response_to_growth_factor_stimulus GO:0070848 12133 545 34 6 1783 8 1 false 0.012297429056281622 0.012297429056281622 0.0 chorion_development GO:0060717 12133 5 34 1 3152 8 2 false 0.012634078962484774 0.012634078962484774 3.8692669693383385E-16 gene_expression GO:0010467 12133 3708 34 26 6052 32 1 false 0.013085315981489456 0.013085315981489456 0.0 regulation_of_protein_ubiquitination GO:0031396 12133 176 34 5 1344 12 2 false 0.01329668161658174 0.01329668161658174 8.0617715234352E-226 localization GO:0051179 12133 3467 34 18 10446 34 1 false 0.013521983884883078 0.013521983884883078 0.0 cytoplasmic_transport GO:0016482 12133 666 34 11 1148 12 1 false 0.013700268964515764 0.013700268964515764 0.0 negative_regulation_of_RNA_splicing GO:0033119 12133 15 34 2 1037 13 3 false 0.013901900469774041 0.013901900469774041 8.39457188486895E-34 renal_interstitial_cell_development GO:0072141 12133 6 34 1 1256 3 2 false 0.014274174444757613 0.014274174444757613 1.8560466395284897E-16 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 34 2 1977 10 3 false 0.01544500773034957 0.01544500773034957 8.49513097758148E-83 organic_substance_biosynthetic_process GO:1901576 12133 4134 34 24 7470 32 2 false 0.017658111860684604 0.017658111860684604 0.0 cellular_sodium_ion_homeostasis GO:0006883 12133 5 34 1 283 1 3 false 0.017667844522967165 0.017667844522967165 6.84978827344915E-11 organelle GO:0043226 12133 7980 34 30 10701 33 1 false 0.017958092489318938 0.017958092489318938 0.0 immune_response GO:0006955 12133 1006 34 7 5335 16 2 false 0.019439484006831292 0.019439484006831292 0.0 enzyme_linked_receptor_protein_signaling_pathway GO:0007167 12133 803 34 6 1975 7 1 false 0.020422365206525697 0.020422365206525697 0.0 water_homeostasis GO:0030104 12133 14 34 1 677 1 1 false 0.020679468242248013 0.020679468242248013 2.3492827505763342E-29 cellular_biosynthetic_process GO:0044249 12133 4077 34 24 7290 32 2 false 0.020710834292664584 0.020710834292664584 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 34 3 2025 7 2 false 0.020813058097719765 0.020813058097719765 5.184659787643375E-271 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 34 2 1199 8 2 false 0.02191108501756683 0.02191108501756683 9.194442294553035E-70 RNA_splicing GO:0008380 12133 307 34 10 601 12 1 false 0.02199980303769477 0.02199980303769477 4.262015823312228E-180 cellular_protein_localization GO:0034613 12133 914 34 12 1438 13 2 false 0.022903467133896013 0.022903467133896013 0.0 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 34 3 856 3 3 false 0.02295692502285049 0.02295692502285049 2.175375701359491E-221 proteolysis_involved_in_cellular_protein_catabolic_process GO:0051603 12133 397 34 6 742 6 2 false 0.023048120002052003 0.023048120002052003 9.121396596563632E-222 regulation_of_organelle_organization GO:0033043 12133 519 34 5 2487 9 2 false 0.023186757748215173 0.023186757748215173 0.0 protein_serine/threonine/tyrosine_kinase_activity GO:0004712 12133 93 34 2 1014 3 1 false 0.023490747235918784 0.023490747235918784 2.468210871514413E-134 glomerular_mesangial_cell_development GO:0072144 12133 4 34 1 167 1 4 false 0.023952095808382517 0.023952095808382517 3.199328908768443E-8 macromolecule_biosynthetic_process GO:0009059 12133 3475 34 23 6537 32 2 false 0.024118867570379305 0.024118867570379305 0.0 smooth_muscle_contractile_fiber GO:0030485 12133 4 34 1 159 1 2 false 0.025157232704403044 0.025157232704403044 3.900612243998485E-8 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 34 9 174 9 1 false 0.025298559612664015 0.025298559612664015 2.5039480990851377E-47 protein_catabolic_process GO:0030163 12133 498 34 7 3569 22 2 false 0.025414565117087673 0.025414565117087673 0.0 pseudopodium GO:0031143 12133 13 34 1 976 2 1 false 0.026475409836085474 0.026475409836085474 9.253153669613935E-30 negative_regulation_of_protein_dephosphorylation GO:0035308 12133 4 34 1 444 3 4 false 0.02684427581518413 0.02684427581518413 6.259846539070891E-10 ubiquitin_conjugating_enzyme_complex GO:0031371 12133 8 34 1 9248 33 2 false 0.02820326311975172 0.02820326311975172 7.5588062911204355E-28 cellular_response_to_stress GO:0033554 12133 1124 34 7 4743 14 2 false 0.02882235640911347 0.02882235640911347 0.0 regulation_of_muscle_cell_differentiation GO:0051147 12133 103 34 2 987 3 2 false 0.0301726399077881 0.0301726399077881 9.48284116235963E-143 positive_regulation_of_histone_modification GO:0031058 12133 40 34 2 963 7 4 false 0.03096293525422808 0.03096293525422808 8.380486405163906E-72 retina_layer_formation GO:0010842 12133 11 34 1 2776 8 4 false 0.03130304977720991 0.03130304977720991 5.397057502530503E-31 receptor_signaling_protein_activity GO:0005057 12133 339 34 3 1070 3 1 false 0.03160920432211269 0.03160920432211269 2.5248591221043436E-289 small_molecule_binding GO:0036094 12133 2102 34 12 8962 30 1 false 0.03202231826481994 0.03202231826481994 0.0 regulation_of_cellular_component_organization GO:0051128 12133 1152 34 8 7336 25 2 false 0.0324201065974971 0.0324201065974971 0.0 neurotrophin_TRK_receptor_signaling_pathway GO:0048011 12133 251 34 4 587 4 2 false 0.03297314159908325 0.03297314159908325 2.854325455984618E-173 regulation_of_isotype_switching GO:0045191 12133 17 34 1 1018 2 6 false 0.03313609696070487 0.03313609696070487 3.003945250869009E-37 positive_regulation_of_protein_modification_process GO:0031401 12133 708 34 7 2417 12 3 false 0.03365435267389153 0.03365435267389153 0.0 DNA_catabolic_process,_exonucleolytic GO:0000738 12133 9 34 1 257 1 2 false 0.03501945525291883 0.03501945525291883 8.548342373692236E-17 mitogen-activated_protein_kinase_kinase_binding GO:0031434 12133 12 34 1 341 1 1 false 0.035190615835779766 0.035190615835779766 2.356690583847287E-22 intracellular_transport_of_viral_material GO:0075733 12133 23 34 2 355 5 2 false 0.035674744243478156 0.035674744243478156 1.1844258992565298E-36 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 34 22 5597 29 2 false 0.03573761584272151 0.03573761584272151 0.0 RNA_helicase_activity GO:0003724 12133 27 34 2 140 2 1 false 0.03607399794449906 0.03607399794449906 1.8047202528374888E-29 cellular_protein_metabolic_process GO:0044267 12133 3038 34 22 5899 32 2 false 0.03635312171587872 0.03635312171587872 0.0 negative_regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090101 12133 80 34 2 695 3 3 false 0.03635957957688677 0.03635957957688677 3.5521820546065696E-107 positive_regulation_of_organelle_organization GO:0010638 12133 217 34 3 2191 8 3 false 0.03685531045457997 0.03685531045457997 1.6765812392172608E-306 heterocycle_biosynthetic_process GO:0018130 12133 3248 34 22 5588 29 2 false 0.0369954380203784 0.0369954380203784 0.0 negative_regulation_of_sodium_ion_transport GO:0010766 12133 5 34 1 135 1 3 false 0.03703703703703773 0.03703703703703773 2.884335739945468E-9 termination_of_RNA_polymerase_II_transcription GO:0006369 12133 44 34 2 1385 10 2 false 0.03775783236017727 0.03775783236017727 3.166663017097352E-84 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 34 22 5686 29 2 false 0.0377776545069359 0.0377776545069359 0.0 organic_substance_transport GO:0071702 12133 1580 34 13 2783 16 1 false 0.03802199492236043 0.03802199492236043 0.0 regulation_of_RNA_splicing GO:0043484 12133 52 34 2 3151 19 3 false 0.03819010286712025 0.03819010286712025 1.4828410310444421E-114 nucleic_acid_binding GO:0003676 12133 2849 34 20 4407 24 2 false 0.03873184163773796 0.03873184163773796 0.0 regulation_of_protein_metabolic_process GO:0051246 12133 1388 34 11 5563 26 3 false 0.03918893562191428 0.03918893562191428 0.0 snRNA_modification GO:0040031 12133 3 34 1 76 1 2 false 0.03947368421052582 0.03947368421052582 1.4224751066856055E-5 activation_of_immune_response GO:0002253 12133 341 34 4 1618 7 2 false 0.039543327559425724 0.039543327559425724 0.0 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 34 23 6146 32 3 false 0.03970760157565899 0.03970760157565899 0.0 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 34 22 5629 29 2 false 0.03972574628928895 0.03972574628928895 0.0 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 34 4 1384 10 2 false 0.04021263284452327 0.04021263284452327 1.3395090025049634E-243 pigment_granule GO:0048770 12133 87 34 2 712 3 1 false 0.04080053258441109 0.04080053258441109 3.4546414966613156E-114 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 34 9 145 9 1 false 0.04140665375930323 0.04140665375930323 1.7288474062512548E-37 mRNA_catabolic_process GO:0006402 12133 181 34 9 592 17 2 false 0.042866133404760816 0.042866133404760816 1.4563864024176219E-157 CRD-mediated_mRNA_stabilization GO:0070934 12133 5 34 2 22 2 1 false 0.04329004329004321 0.04329004329004321 3.79737221842484E-5 protein_transport GO:0015031 12133 1099 34 12 1627 13 2 false 0.04355691177600437 0.04355691177600437 0.0 positive_regulation_of_DNA-dependent_transcription,_initiation GO:2000144 12133 7 34 1 1100 7 4 false 0.043821382761818885 0.043821382761818885 2.6362658013915236E-18 intracellular_part GO:0044424 12133 9083 34 33 9983 33 2 false 0.04402210787217549 0.04402210787217549 0.0 regulation_of_immune_response GO:0050776 12133 533 34 5 2461 10 3 false 0.04469133807022672 0.04469133807022672 0.0 cellular_response_to_growth_factor_stimulus GO:0071363 12133 532 34 6 1356 8 2 false 0.04474276473580815 0.04474276473580815 0.0 activation_of_MAPKK_activity GO:0000186 12133 64 34 2 496 3 3 false 0.045144668574232 0.045144668574232 2.7437381948522894E-82 positive_regulation_of_ubiquitin-protein_ligase_activity GO:0051443 12133 80 34 4 362 7 4 false 0.04518293616679611 0.04518293616679611 1.827388630734988E-82 primary_metabolic_process GO:0044238 12133 7288 34 32 8027 32 1 false 0.04518919466222815 0.04518919466222815 0.0 cellular_response_to_organic_substance GO:0071310 12133 1347 34 8 1979 8 2 false 0.04575961672246531 0.04575961672246531 0.0 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 34 6 5051 14 3 false 0.04611708010683446 0.04611708010683446 0.0 response_to_abiotic_stimulus GO:0009628 12133 676 34 5 5200 16 1 false 0.0468334889065987 0.0468334889065987 0.0 gamma-tubulin_complex GO:0000930 12133 12 34 1 3008 12 2 false 0.046919771258675844 0.046919771258675844 8.923684673074959E-34 molecular_function GO:0003674 12133 10257 34 34 11221 34 1 false 0.04694334547511466 0.04694334547511466 0.0 nucleoplasm GO:0005654 12133 1443 34 14 2767 19 2 false 0.04706519259147983 0.04706519259147983 0.0 apoptotic_signaling_pathway GO:0097190 12133 305 34 3 3954 11 2 false 0.04711302752378981 0.04711302752378981 0.0 positive_regulation_of_histone_H3-K36_methylation GO:0000416 12133 1 34 1 21 1 3 false 0.04761904761904764 0.04761904761904764 0.04761904761904764 signal_transduction_by_phosphorylation GO:0023014 12133 307 34 3 3947 11 2 false 0.048113943162391974 0.048113943162391974 0.0 microtubule_basal_body GO:0005932 12133 41 34 1 832 1 2 false 0.04927884615386388 0.04927884615386388 1.7160205681644377E-70 response_to_hypoxia GO:0001666 12133 200 34 3 2540 11 2 false 0.04949155753126602 0.04949155753126602 2.6634431659671552E-303 viral_budding GO:0046755 12133 2 34 1 557 14 1 false 0.04968161915708906 0.04968161915708906 6.458029267788538E-6 ribose_phosphate_metabolic_process GO:0019693 12133 1207 34 6 3007 8 3 false 0.05044941003227646 0.05044941003227646 0.0 positive_regulation_of_kinase_activity GO:0033674 12133 438 34 3 1181 3 3 false 0.050792118433920584 0.050792118433920584 0.0 negative_regulation_of_cellular_response_to_growth_factor_stimulus GO:0090288 12133 78 34 2 2735 13 4 false 0.05110772053777268 0.05110772053777268 2.836340851870023E-153 connective_tissue_development GO:0061448 12133 156 34 2 1132 3 1 false 0.05151117489824355 0.05151117489824355 2.187737558502385E-196 U12-type_spliceosomal_complex GO:0005689 12133 24 34 3 150 6 1 false 0.05231739610197527 0.05231739610197527 2.5760759444825708E-28 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 34 3 1112 3 4 false 0.052497141606074 0.052497141606074 1.302733E-318 telomeric_DNA_binding GO:0042162 12133 16 34 1 1189 4 1 false 0.05281529312941407 0.05281529312941407 1.4512187070438412E-36 hydrolase_activity,_acting_on_acid_anhydrides GO:0016817 12133 1085 34 5 2556 6 1 false 0.05323829826648905 0.05323829826648905 0.0 positive_regulation_of_phosphorylation GO:0042327 12133 563 34 3 1487 3 3 false 0.054094279428261456 0.054094279428261456 0.0 cellular_protein_catabolic_process GO:0044257 12133 409 34 6 3174 22 3 false 0.05416781789832488 0.05416781789832488 0.0 MAP_kinase_kinase_activity GO:0004708 12133 74 34 2 521 3 3 false 0.054286059319159315 0.054286059319159315 6.903948166738437E-92 regulation_of_cellular_response_to_growth_factor_stimulus GO:0090287 12133 135 34 2 6380 18 3 false 0.05451385220201633 0.05451385220201633 2.5067679665083333E-283 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 34 7 374 8 2 false 0.054670735310183745 0.054670735310183745 2.0954491420584897E-111 response_to_transforming_growth_factor_beta_stimulus GO:0071559 12133 180 34 3 1130 6 2 false 0.05491032996036138 0.05491032996036138 1.9819409219356823E-214 positive_regulation_of_cell_communication GO:0010647 12133 820 34 5 4819 13 3 false 0.05504357554484491 0.05504357554484491 0.0 regulation_of_potassium_ion_transmembrane_transport GO:1901379 12133 12 34 1 216 1 3 false 0.05555555555555571 0.05555555555555571 6.338882729411382E-20 cytoplasmic_dynein_complex GO:0005868 12133 13 34 1 5120 23 2 false 0.05691499461737542 0.05691499461737542 3.8053308288659296E-39 adipose_tissue_development GO:0060612 12133 19 34 1 1929 6 2 false 0.05773474090212248 0.05773474090212248 5.039701939128339E-46 innate_immune_response GO:0045087 12133 626 34 6 1268 7 2 false 0.05796152672738568 0.05796152672738568 0.0 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 34 10 2643 13 1 false 0.05837104391880254 0.05837104391880254 0.0 positive_regulation_of_molecular_function GO:0044093 12133 1303 34 8 10257 34 2 false 0.058721682117651615 0.058721682117651615 0.0 regulation_of_potassium_ion_transmembrane_transporter_activity GO:1901016 12133 9 34 1 153 1 3 false 0.05882352941176151 0.05882352941176151 1.0038611131963863E-14 cellular_response_to_oxygen_levels GO:0071453 12133 85 34 2 1663 8 2 false 0.05914605863973749 0.05914605863973749 4.192529980934564E-145 positive_regulation_of_ion_transmembrane_transporter_activity GO:0032414 12133 28 34 1 473 1 3 false 0.059196617336147846 0.059196617336147846 8.750359231366189E-46 neural_retina_development GO:0003407 12133 24 34 1 3152 8 3 false 0.05937907299303462 0.05937907299303462 7.324194080919859E-61 microtubule_associated_complex GO:0005875 12133 110 34 2 3267 12 3 false 0.059499704478794255 0.059499704478794255 2.821671595839563E-208 intracellular GO:0005622 12133 9171 34 33 9983 33 1 false 0.06054763313429336 0.06054763313429336 0.0 regulation_of_ubiquitin-protein_ligase_activity GO:0051438 12133 94 34 4 389 7 3 false 0.06137470010528807 0.06137470010528807 8.074632425282073E-93 positive_regulation_of_immune_system_process GO:0002684 12133 540 34 5 3595 15 3 false 0.06162130067004092 0.06162130067004092 0.0 positive_regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033145 12133 9 34 1 856 6 3 false 0.06162450286464748 0.06162450286464748 1.5339974177634096E-21 regulation_of_immune_system_process GO:0002682 12133 794 34 5 6789 19 2 false 0.06230695681447481 0.06230695681447481 0.0 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 34 3 750 3 3 false 0.06297950208128138 0.06297950208128138 3.090255244762607E-218 positive_regulation_of_defense_response GO:0031349 12133 229 34 3 1621 7 3 false 0.06300181248410754 0.06300181248410754 6.85443065618377E-286 cellular_protein_complex_localization GO:0034629 12133 5 34 1 930 12 2 false 0.06300468211634117 0.06300468211634117 1.7435880605018067E-13 epithelial_cell_differentiation_involved_in_kidney_development GO:0035850 12133 31 34 1 491 1 3 false 0.06313645621180647 0.06313645621180647 8.158001597817135E-50 phosphoserine_binding GO:0050815 12133 4 34 1 125 2 2 false 0.06322580645161026 0.06322580645161026 1.0318453263855228E-7 regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051439 12133 76 34 2 1056 6 3 false 0.06345678537738014 0.06345678537738014 4.764817151311381E-118 negative_regulation_of_metabolic_process GO:0009892 12133 1354 34 9 8327 32 3 false 0.0636928647889188 0.0636928647889188 0.0 regulation_of_histone_H3-K36_methylation GO:0000414 12133 2 34 1 31 1 2 false 0.0645161290322579 0.0645161290322579 0.002150537634408595 paraspeckles GO:0042382 12133 6 34 1 272 3 1 false 0.06496153196825426 0.06496153196825426 1.8794561691225117E-12 positive_regulation_of_signal_transduction GO:0009967 12133 782 34 5 3650 11 5 false 0.06517000451833202 0.06517000451833202 0.0 regulation_of_DNA-dependent_transcription,_initiation GO:2000142 12133 15 34 1 2670 12 3 false 0.065502074511238 0.065502074511238 5.444282950561458E-40 channel_inhibitor_activity GO:0016248 12133 20 34 1 304 1 2 false 0.06578947368420382 0.06578947368420382 1.0141079171115058E-31 positive_regulation_of_sodium_ion_transport GO:0010765 12133 11 34 1 166 1 3 false 0.06626506024096748 0.06626506024096748 2.123209741249517E-17 response_to_DNA_damage_stimulus GO:0006974 12133 570 34 6 1124 7 1 false 0.06670025590198062 0.06670025590198062 0.0 positive_regulation_of_DNA_metabolic_process GO:0051054 12133 92 34 2 2322 11 4 false 0.06768687353475382 0.06768687353475382 1.6937907011714837E-167 regulation_of_blood_pressure GO:0008217 12133 117 34 2 2120 8 2 false 0.06797348202406928 0.06797348202406928 6.820682324461924E-196 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 34 9 7606 32 4 false 0.0690594428267674 0.0690594428267674 0.0 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 34 3 912 3 2 false 0.0691921927803203 0.0691921927803203 2.059888800891414E-267 sodium_channel_inhibitor_activity GO:0019871 12133 3 34 1 43 1 3 false 0.06976744186046464 0.06976744186046464 8.103071063933269E-5 ion_channel_inhibitor_activity GO:0008200 12133 20 34 1 286 1 2 false 0.06993006993007066 0.06993006993007066 3.5818833657211076E-31 positive_regulation_of_signaling GO:0023056 12133 817 34 5 4861 14 3 false 0.07081393442516973 0.07081393442516973 0.0 DNA_double-strand_break_processing GO:0000729 12133 8 34 1 110 1 2 false 0.07272727272727175 0.07272727272727175 2.4407768686605466E-12 regulation_of_histone_ubiquitination GO:0033182 12133 4 34 1 265 5 3 false 0.07376945120103724 0.07376945120103724 4.978567515771174E-9 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 34 8 4597 14 2 false 0.0737875005112241 0.0737875005112241 0.0 retina_morphogenesis_in_camera-type_eye GO:0060042 12133 27 34 1 2812 8 4 false 0.0743707584388911 0.0743707584388911 9.288592992489042E-66 photoreceptor_cell_development GO:0042461 12133 25 34 1 660 2 2 false 0.07437807513680594 0.07437807513680594 7.978897443638017E-46 DNA_repair GO:0006281 12133 368 34 5 977 7 2 false 0.07466644767963461 0.07466644767963461 3.284245924949814E-280 intracellular_organelle_lumen GO:0070013 12133 2919 34 19 5320 27 2 false 0.07487317069734109 0.07487317069734109 0.0 positive_regulation_of_cation_channel_activity GO:2001259 12133 17 34 1 224 1 3 false 0.07589285714285353 0.07589285714285353 7.366387194248368E-26 regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900739 12133 24 34 1 315 1 3 false 0.07619047619048347 0.07619047619048347 1.6734366655590734E-36 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 34 3 6813 21 2 false 0.07630281662100477 0.07630281662100477 0.0 histone_pre-mRNA_DCP_binding GO:0071208 12133 4 34 1 763 15 1 false 0.07649438240600794 0.07649438240600794 7.13729230310747E-11 cilium_basal_body GO:0036064 12133 7 34 1 90 1 2 false 0.0777777777777789 0.0777777777777789 1.338441618908599E-10 eye_photoreceptor_cell_differentiation GO:0001754 12133 28 34 1 2776 8 3 false 0.07799469892719874 0.07799469892719874 1.3419266613417602E-67 blood_vessel_development GO:0001568 12133 420 34 3 3152 8 3 false 0.07867299922353232 0.07867299922353232 0.0 regulation_of_transcription_initiation_from_RNA_polymerase_II_promoter GO:0060260 12133 13 34 1 1243 8 3 false 0.08088882816918438 0.08088882816918438 3.9219319072235074E-31 cytoplasmic_part GO:0044444 12133 5117 34 23 9083 33 2 false 0.08309047700682975 0.08309047700682975 0.0 regulation_of_histone_modification GO:0031056 12133 77 34 2 1240 8 3 false 0.08353027453034524 0.08353027453034524 1.0351200557646026E-124 photoreceptor_cell_differentiation GO:0046530 12133 35 34 1 812 2 1 false 0.08439984693231663 0.08439984693231663 3.181338504659356E-62 regulation_of_protein_modification_process GO:0031399 12133 1001 34 8 2566 13 2 false 0.08472901606636203 0.08472901606636203 0.0 cellular_monovalent_inorganic_cation_homeostasis GO:0030004 12133 26 34 1 306 1 2 false 0.08496732026142838 0.08496732026142838 2.8281153145438213E-38 regulation_of_response_to_stimulus GO:0048583 12133 2074 34 9 7292 20 2 false 0.08507686182204807 0.08507686182204807 0.0 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 34 3 1525 7 1 false 0.08529266552728075 0.08529266552728075 1.2095302863090285E-289 ribonucleoprotein_complex_assembly GO:0022618 12133 117 34 2 646 3 3 false 0.08608456846630368 0.08608456846630368 4.631331466925404E-132 DNA-dependent_transcription,_initiation GO:0006352 12133 225 34 4 2751 21 2 false 0.08656698686575444 0.08656698686575444 0.0 sodium_ion_homeostasis GO:0055078 12133 26 34 1 299 1 2 false 0.08695652173913307 0.08695652173913307 5.299686091705976E-38 biological_process GO:0008150 12133 10446 34 34 11221 34 1 false 0.08742051938229528 0.08742051938229528 0.0 positive_regulation_of_isotype_switching GO:0045830 12133 12 34 1 137 1 5 false 0.08759124087591477 0.08759124087591477 1.7989734568189992E-17 hormone_receptor_binding GO:0051427 12133 122 34 2 918 4 1 false 0.08773451489779074 0.08773451489779074 1.5301276126382055E-155 response_to_stress GO:0006950 12133 2540 34 11 5200 16 1 false 0.088763385285909 0.088763385285909 0.0 regulation_of_striated_muscle_cell_differentiation GO:0051153 12133 68 34 2 227 2 2 false 0.0888074539004326 0.0888074539004326 1.1311225924750782E-59 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 34 6 5778 17 3 false 0.09032112318366575 0.09032112318366575 0.0 regulation_of_chromosome_organization GO:0033044 12133 114 34 2 1070 5 2 false 0.09079287181549021 0.09079287181549021 5.856752364330647E-157 histone_H3-K36_methylation GO:0010452 12133 6 34 1 66 1 1 false 0.09090909090909147 0.09090909090909147 1.1006092444484753E-8 cellular_response_to_hypoxia GO:0071456 12133 79 34 2 1210 8 3 false 0.09119420841252757 0.09119420841252757 3.484581288071841E-126 virion_assembly GO:0019068 12133 11 34 1 2070 18 4 false 0.09181242825572729 0.09181242825572729 1.3710102562261885E-29 organic_substance_metabolic_process GO:0071704 12133 7451 34 32 8027 32 1 false 0.09185047882110242 0.09185047882110242 0.0 vasculature_development GO:0001944 12133 441 34 3 2686 7 2 false 0.09205420522032097 0.09205420522032097 0.0 signal_transduction_in_response_to_DNA_damage GO:0042770 12133 114 34 2 2180 10 2 false 0.09270100577496136 0.09270100577496136 1.341003616993524E-193 regulation_of_mitochondrial_outer_membrane_permeabilization GO:1901028 12133 33 34 1 354 1 4 false 0.09322033898306151 0.09322033898306151 3.0911895026883726E-47 regulation_of_protein_dephosphorylation GO:0035304 12133 14 34 1 1152 8 3 false 0.09345820017640455 0.09345820017640455 1.3017113495112525E-32 protein_polyubiquitination GO:0000209 12133 163 34 5 548 9 1 false 0.0939193526258782 0.0939193526258782 3.681189236491621E-144 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 34 2 86 2 2 false 0.09603283173734763 0.09603283173734763 6.233113581740502E-23 ubiquitin_ligase_complex GO:0000151 12133 147 34 2 9248 33 2 false 0.09626507256939536 0.09626507256939536 0.0 endocytosis GO:0006897 12133 411 34 3 895 3 2 false 0.09645771587875936 0.09645771587875936 2.7872223899360555E-267 positive_regulation_of_biological_process GO:0048518 12133 3081 34 14 10446 34 2 false 0.09783091681663958 0.09783091681663958 0.0 multivesicular_body_sorting_pathway GO:0071985 12133 17 34 1 2490 15 2 false 0.09791979240129908 0.09791979240129908 6.909596477174519E-44 regulation_of_vesicle-mediated_transport GO:0060627 12133 196 34 2 6585 18 3 false 0.09876661813350254 0.09876661813350254 0.0 cell_part GO:0044464 12133 9983 34 33 10701 33 2 false 0.1007086788513171 0.1007086788513171 0.0 cell GO:0005623 12133 9984 34 33 10701 33 1 false 0.10104265397027096 0.10104265397027096 0.0 sodium_channel_activity GO:0005272 12133 26 34 1 256 1 3 false 0.10156249999999863 0.10156249999999863 3.647595212320824E-36 renal_system_vasculature_development GO:0061437 12133 20 34 1 571 3 2 false 0.10161311669169311 0.10161311669169311 2.509501501235589E-37 response_to_organic_substance GO:0010033 12133 1783 34 8 2369 8 1 false 0.10256497285684876 0.10256497285684876 0.0 signal_transduction_by_p53_class_mediator GO:0072331 12133 127 34 2 1813 8 1 false 0.1032332017645462 0.1032332017645462 4.219154160176784E-199 positive_regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902110 12133 37 34 1 1374 4 3 false 0.10354989058780933 0.10354989058780933 1.7604614397711276E-73 negative_regulation_of_cellular_component_organization GO:0051129 12133 317 34 3 7778 28 4 false 0.1038842963660552 0.1038842963660552 0.0 negative_regulation_of_ligase_activity GO:0051352 12133 71 34 2 1003 8 3 false 0.10482178976660506 0.10482178976660506 8.698138776450475E-111 antigen_binding GO:0003823 12133 33 34 1 8962 30 1 false 0.10492707096998011 0.10492707096998011 3.427206781755235E-94 nuclear_matrix GO:0016363 12133 81 34 2 2767 19 2 false 0.10501910469435806 0.10501910469435806 2.9785824972298125E-158 intrinsic_apoptotic_signaling_pathway GO:0097193 12133 135 34 2 1881 8 2 false 0.10764470250733915 0.10764470250733915 3.367676499542027E-210 positive_regulation_of_immune_response GO:0050778 12133 394 34 4 1600 8 4 false 0.1081495009700073 0.1081495009700073 0.0 nucleoside_phosphate_metabolic_process GO:0006753 12133 1319 34 6 2807 8 3 false 0.10820094539987671 0.10820094539987671 0.0 cellular_response_to_transforming_growth_factor_beta_stimulus GO:0071560 12133 179 34 3 859 6 3 false 0.10872328386940822 0.10872328386940822 3.480270935062193E-190 regulation_of_mitochondrial_membrane_permeability_involved_in_apoptotic_process GO:1902108 12133 39 34 1 1375 4 3 false 0.1088319182398918 0.1088319182398918 1.4191902379759833E-76 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 34 4 1079 5 3 false 0.1091242984466258 0.1091242984466258 5.98264E-319 negative_regulation_of_muscle_cell_differentiation GO:0051148 12133 33 34 1 584 2 3 false 0.10991212199535672 0.10991212199535672 1.1148204606376211E-54 hippocampus_development GO:0021766 12133 46 34 1 3152 8 4 false 0.11107583434748815 0.11107583434748815 8.889994332374666E-104 excretion GO:0007588 12133 50 34 1 1272 3 1 false 0.11343553980254824 0.11343553980254824 4.8139348402185623E-91 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 34 8 4044 24 3 false 0.11358862830214585 0.11358862830214585 0.0 vascular_smooth_muscle_contraction GO:0014829 12133 10 34 1 88 1 2 false 0.11363636363636048 0.11363636363636048 2.215493107028815E-13 maintenance_of_protein_location_in_nucleus GO:0051457 12133 14 34 1 239 2 2 false 0.11395520551313984 0.11395520551313984 6.477405383474671E-23 nuclear_body GO:0016604 12133 272 34 3 805 4 1 false 0.11464424972023009 0.11464424972023009 8.12188174084084E-223 glomerulus_development GO:0032835 12133 48 34 1 3152 8 3 false 0.11564980553995541 0.11564980553995541 2.079589057162791E-107 U2-type_spliceosomal_complex GO:0005684 12133 3 34 1 150 6 1 false 0.11600943225105198 0.11600943225105198 1.813894431344149E-6 Notch_receptor_processing GO:0007220 12133 17 34 1 3038 22 1 false 0.11651675751016011 0.11651675751016011 2.325698863690895E-45 organelle_lumen GO:0043233 12133 2968 34 19 5401 28 2 false 0.1171155810888294 0.1171155810888294 0.0 hippo_signaling_cascade GO:0035329 12133 28 34 1 1813 8 1 false 0.11729044904498923 0.11729044904498923 2.187819615524224E-62 regulation_of_kinase_activity GO:0043549 12133 654 34 3 1335 3 3 false 0.11729278023070014 0.11729278023070014 0.0 positive_regulation_of_transcription_initiation_from_RNA_polymerase_II_promoter GO:0060261 12133 6 34 1 196 4 3 false 0.11780388832898002 0.11780388832898002 1.3719812583394723E-11 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 34 3 417 3 4 false 0.11792410371980254 0.11792410371980254 8.022991700655629E-125 ephrin_receptor_binding GO:0046875 12133 29 34 1 918 4 1 false 0.1206870203887151 0.1206870203887151 1.6526990639165767E-55 cell_differentiation_involved_in_kidney_development GO:0061005 12133 40 34 1 2189 7 2 false 0.12126712948057417 0.12126712948057417 2.8675090543885934E-86 positive_regulation_of_transporter_activity GO:0032411 12133 34 34 1 2101 8 4 false 0.12255488427687236 0.12255488427687236 4.2098203958278254E-75 cytoplasmic_stress_granule GO:0010494 12133 29 34 1 5117 23 2 false 0.1227850572640497 0.1227850572640497 2.627932865737447E-77 DNA-dependent_transcription,_termination GO:0006353 12133 80 34 2 2751 21 2 false 0.12293916725886861 0.12293916725886861 1.5820458311792457E-156 negative_regulation_of_cellular_process GO:0048523 12133 2515 34 12 9689 33 3 false 0.1232267819555847 0.1232267819555847 0.0 glomerulus_vasculature_development GO:0072012 12133 19 34 1 444 3 3 false 0.12322897650205968 0.12322897650205968 9.004361904208676E-34 SH2_domain_binding GO:0042169 12133 31 34 1 486 2 1 false 0.12362649017858361 0.12362649017858361 1.1318841086292139E-49 regulation_of_signal_transduction GO:0009966 12133 1603 34 7 3826 11 4 false 0.12414922611960291 0.12414922611960291 0.0 kidney_vasculature_development GO:0061440 12133 20 34 1 161 1 2 false 0.1242236024844735 0.1242236024844735 6.083753393714536E-26 positive_regulation_of_protein_binding GO:0032092 12133 37 34 1 6397 23 3 false 0.12510198126934705 0.12510198126934705 2.3062856812384995E-98 regulation_of_endocytosis GO:0030100 12133 113 34 2 1437 8 3 false 0.12564528249881368 0.12564528249881368 3.3139638850760945E-171 cellular_membrane_organization GO:0016044 12133 784 34 5 7541 26 2 false 0.1262131032249455 0.1262131032249455 0.0 regulation_of_MAP_kinase_activity GO:0043405 12133 268 34 3 533 3 3 false 0.12641375435924845 0.12641375435924845 1.0382438249699724E-159 response_to_peptide GO:1901652 12133 322 34 2 904 2 2 false 0.1266207038486307 0.1266207038486307 7.8711156655671515E-255 negative_regulation_of_endocytosis GO:0045806 12133 23 34 1 859 5 4 false 0.12717740937686228 0.12717740937686228 1.1473487217608225E-45 intracellular_signal_transduction GO:0035556 12133 1813 34 8 3547 11 1 false 0.12790800795826987 0.12790800795826987 0.0 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 34 22 4989 29 5 false 0.12878341063874088 0.12878341063874088 0.0 glomerular_mesangium_development GO:0072109 12133 11 34 1 163 2 2 false 0.13080360524121898 0.13080360524121898 2.611469323021833E-17 positive_regulation_of_cellular_process GO:0048522 12133 2811 34 13 9694 33 3 false 0.1310558059667998 0.1310558059667998 0.0 nucleoside_metabolic_process GO:0009116 12133 1083 34 5 2072 6 4 false 0.1317579477863481 0.1317579477863481 0.0 helicase_activity GO:0004386 12133 140 34 2 1059 5 1 false 0.1325937728451892 0.1325937728451892 6.632628106941949E-179 positive_regulation_of_peptidyl-lysine_acetylation GO:2000758 12133 17 34 1 127 1 3 false 0.13385826771653558 0.13385826771653558 1.8751500945612253E-21 regulation_of_potassium_ion_transport GO:0043266 12133 32 34 1 238 1 2 false 0.13445378151259108 0.13445378151259108 2.0777607490676014E-40 regulation_of_cation_channel_activity GO:2001257 12133 33 34 1 244 1 2 false 0.13524590163933084 0.13524590163933084 1.3783310605710322E-41 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 34 9 5303 26 3 false 0.13542691967481896 0.13542691967481896 0.0 positive_regulation_of_protein_acetylation GO:1901985 12133 17 34 1 823 7 3 false 0.1364023271954522 0.1364023271954522 1.1521858928998402E-35 regulation_of_tight_junction_assembly GO:2000810 12133 8 34 1 58 1 2 false 0.13793103448276028 0.13793103448276028 5.217035699399583E-10 regulation_of_transmembrane_transporter_activity GO:0022898 12133 78 34 1 563 1 3 false 0.13854351687388652 0.13854351687388652 8.813007984613145E-98 vacuolar_protein_catabolic_process GO:0007039 12133 10 34 1 409 6 1 false 0.13881853174982475 0.13881853174982475 3.095189671373722E-20 glomerular_mesangial_cell_differentiation GO:0072008 12133 5 34 1 36 1 4 false 0.13888888888888903 0.13888888888888903 2.6525761819879548E-6 mitotic_spindle_assembly_checkpoint GO:0007094 12133 35 34 1 953 4 4 false 0.13921515268778112 0.13921515268778112 1.0482452124052062E-64 regulation_of_transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0090092 12133 139 34 2 1663 8 2 false 0.13924864700517267 0.13924864700517267 7.181952736648417E-207 platelet_activation GO:0030168 12133 203 34 2 863 3 2 false 0.1396310037335863 0.1396310037335863 1.0918730712206789E-203 positive_regulation_of_transferase_activity GO:0051347 12133 445 34 3 2275 7 3 false 0.1402478056449964 0.1402478056449964 0.0 eye_morphogenesis GO:0048592 12133 102 34 1 725 1 2 false 0.14068965517240326 0.14068965517240326 2.944718956085604E-127 nuclear_periphery GO:0034399 12133 97 34 2 2767 19 2 false 0.1415468275564612 0.1415468275564612 7.041791399430774E-182 cerebral_cortex_development GO:0021987 12133 60 34 1 3152 8 3 false 0.14266366870265923 0.14266366870265923 1.7800361131587683E-128 MAP_kinase_kinase_kinase_activity GO:0004709 12133 26 34 1 520 3 3 false 0.1428861561808948 0.1428861561808948 1.8429565665115438E-44 positive_regulation_of_DNA_recombination GO:0045911 12133 13 34 1 260 3 3 false 0.1431489629164187 0.1431489629164187 3.404510615248639E-22 establishment_of_localization_in_cell GO:0051649 12133 1633 34 12 2978 17 2 false 0.14324497673075973 0.14324497673075973 0.0 circulatory_system_process GO:0003013 12133 307 34 2 1272 3 1 false 0.14641089567505375 0.14641089567505375 1.974873217376429E-304 limbic_system_development GO:0021761 12133 61 34 1 2686 7 2 false 0.14869719765803402 0.14869719765803402 6.732470891549266E-126 ubiquitin-dependent_protein_catabolic_process_via_the_multivesicular_body_sorting_pathway GO:0043162 12133 10 34 1 379 6 3 false 0.14915097071341488 0.14915097071341488 6.689174917849262E-20 regulation_of_protein_kinase_activity GO:0045859 12133 621 34 3 1169 3 3 false 0.1495704253511343 0.1495704253511343 0.0 mesangial_cell_differentiation GO:0072007 12133 6 34 1 40 1 1 false 0.15000000000000094 0.15000000000000094 2.6052657631605334E-7 MAP_kinase_activity GO:0004707 12133 277 34 3 520 3 2 false 0.15039073565077132 0.15039073565077132 2.5282679507054518E-155 regulation_of_ion_transmembrane_transporter_activity GO:0032412 12133 73 34 1 485 1 3 false 0.15051546391749993 0.15051546391749993 1.1784649326580688E-88 camera-type_eye_photoreceptor_cell_differentiation GO:0060219 12133 8 34 1 53 1 3 false 0.1509433962264137 0.1509433962264137 1.1282572236019818E-9 vasculogenesis GO:0001570 12133 62 34 1 3056 8 4 false 0.15139608302997995 0.15139608302997995 4.885889713794216E-131 SUMO_ligase_activity GO:0019789 12133 9 34 1 335 6 1 false 0.15180858391766178 0.15180858391766178 7.610794818623194E-18 establishment_of_RNA_localization GO:0051236 12133 124 34 2 2839 16 2 false 0.15261133818118203 0.15261133818118203 1.4765023034812589E-220 DNA_recombination GO:0006310 12133 190 34 3 791 6 1 false 0.15347109068455161 0.15347109068455161 1.2250789605162758E-188 anion_binding GO:0043168 12133 2280 34 9 4448 13 1 false 0.15384541532988222 0.15384541532988222 0.0 negative_regulation_of_biological_process GO:0048519 12133 2732 34 12 10446 34 2 false 0.1539304775619184 0.1539304775619184 0.0 positive_regulation_of_innate_immune_response GO:0045089 12133 178 34 3 740 6 4 false 0.15393217205730883 0.15393217205730883 1.4450011889246649E-176 cellular_response_to_peptide GO:1901653 12133 247 34 2 625 2 3 false 0.15580000000000666 0.15580000000000666 2.2359681686760748E-181 negative_regulation_of_striated_muscle_cell_differentiation GO:0051154 12133 17 34 1 208 2 3 false 0.15714418431809243 0.15714418431809243 2.72756232006883E-25 negative_regulation_of_ERBB_signaling_pathway GO:1901185 12133 39 34 1 705 3 3 false 0.15715667311408366 0.15715667311408366 4.9570646354646075E-65 regulation_of_Rac_protein_signal_transduction GO:0035020 12133 23 34 1 278 2 2 false 0.15889670934732794 0.15889670934732794 4.034778444759645E-34 regulation_of_mitochondrial_membrane_permeability GO:0046902 12133 46 34 1 2152 8 3 false 0.15898240036050804 0.15898240036050804 4.367031159968052E-96 positive_regulation_of_metabolic_process GO:0009893 12133 1872 34 10 8366 32 3 false 0.1594139616478209 0.1594139616478209 0.0 response_to_osmotic_stress GO:0006970 12133 43 34 1 2681 11 2 false 0.16321836463858427 0.16321836463858427 3.246680302266631E-95 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 34 4 5027 23 3 false 0.16392735714639806 0.16392735714639806 0.0 negative_regulation_of_systemic_arterial_blood_pressure GO:0003085 12133 11 34 1 67 1 2 false 0.16417910447761364 0.16417910447761364 7.781717560880856E-13 snRNA_metabolic_process GO:0016073 12133 15 34 1 258 3 1 false 0.16507803309655383 0.16507803309655383 1.3254371174076553E-24 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 34 5 1541 10 3 false 0.1652154342575287 0.1652154342575287 0.0 outer_membrane GO:0019867 12133 112 34 1 4398 7 1 false 0.16531165717443108 0.16531165717443108 7.412183245910406E-226 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 34 3 1399 4 3 false 0.16626320497370936 0.16626320497370936 0.0 activation_of_MAPK_activity GO:0000187 12133 158 34 3 286 3 2 false 0.1671675988948046 0.1671675988948046 8.207976102051858E-85 negative_regulation_of_apoptotic_process GO:0043066 12133 537 34 3 1377 4 3 false 0.1675124148935439 0.1675124148935439 0.0 regulation_of_DNA_metabolic_process GO:0051052 12133 188 34 2 4316 17 3 false 0.16764067180010458 0.16764067180010458 0.0 protein_insertion_into_mitochondrial_membrane GO:0051204 12133 25 34 1 1644 12 4 false 0.1684853081946411 0.1684853081946411 7.460154269678152E-56 activating_transcription_factor_binding GO:0033613 12133 294 34 2 715 2 1 false 0.1687371452077427 0.1687371452077427 1.6086726333731214E-209 response_to_endogenous_stimulus GO:0009719 12133 982 34 5 5200 16 1 false 0.16918103698000447 0.16918103698000447 0.0 monovalent_inorganic_cation_homeostasis GO:0055067 12133 56 34 1 330 1 1 false 0.16969696969696543 0.16969696969696543 9.24814230107908E-65 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 34 4 200 9 3 false 0.1704382094734657 0.1704382094734657 7.491323649368413E-49 negative_regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043154 12133 63 34 1 1373 4 3 false 0.17146358047444693 0.17146358047444693 1.783777218833555E-110 regulation_of_sodium_ion_transport GO:0002028 12133 37 34 1 215 1 2 false 0.17209302325580766 0.17209302325580766 1.8499074186131244E-42 Rac_protein_signal_transduction GO:0016601 12133 33 34 1 365 2 1 false 0.17287370164083218 0.17287370164083218 1.0734561739608448E-47 sodium_ion_transport GO:0006814 12133 95 34 1 545 1 2 false 0.17431192660552194 0.17431192660552194 6.918862196703055E-109 renal_interstitial_cell_differentiation GO:0072071 12133 7 34 1 40 1 1 false 0.17500000000000104 0.17500000000000104 5.363782453565752E-8 RNA-dependent_ATPase_activity GO:0008186 12133 21 34 1 228 2 1 false 0.1760955251564932 0.1760955251564932 4.020483440001667E-30 sodium_channel_regulator_activity GO:0017080 12133 14 34 1 78 1 2 false 0.17948717948717585 0.17948717948717585 9.768201397951623E-16 lymphocyte_activation_involved_in_immune_response GO:0002285 12133 78 34 1 432 1 2 false 0.18055555555552838 0.18055555555552838 5.057484756456232E-88 methylation GO:0032259 12133 195 34 2 8027 32 1 false 0.1819136591657598 0.1819136591657598 0.0 RNA_methyltransferase_activity GO:0008173 12133 23 34 1 126 1 2 false 0.1825396825396866 0.1825396825396866 1.0792211566104033E-25 regulation_of_muscle_organ_development GO:0048634 12133 106 34 1 1105 2 2 false 0.1827316545347932 0.1827316545347932 5.2870889259577626E-151 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 34 2 217 4 1 false 0.18364127079832696 0.18364127079832696 4.514459380304185E-47 ATP-dependent_helicase_activity GO:0008026 12133 98 34 2 228 2 2 false 0.18366952623849817 0.18366952623849817 4.1384935546953996E-67 nephron_development GO:0072006 12133 79 34 1 3152 8 3 false 0.18395995211964364 0.18395995211964364 9.804100439545243E-160 negative_regulation_of_mitosis GO:0045839 12133 43 34 1 656 3 5 false 0.18430045658035457 0.18430045658035457 1.8426541499010044E-68 response_to_oxygen_levels GO:0070482 12133 214 34 3 676 5 1 false 0.18491303749934163 0.18491303749934163 1.6255941364061853E-182 positive_regulation_of_B_cell_activation GO:0050871 12133 52 34 1 280 1 3 false 0.18571428571426857 0.18571428571426857 7.083953117162652E-58 post-embryonic_development GO:0009791 12133 81 34 1 4373 11 3 false 0.18608445306499524 0.18608445306499524 1.5270071764931075E-174 positive_regulation_of_response_to_DNA_damage_stimulus GO:2001022 12133 44 34 1 3212 15 4 false 0.1872691151348914 0.1872691151348914 1.7987290458431554E-100 negative_regulation_of_nuclear_division GO:0051784 12133 43 34 1 436 2 3 false 0.18772540335334276 0.18772540335334276 1.634686522119006E-60 ion_transmembrane_transport GO:0034220 12133 556 34 3 970 3 2 false 0.18789129980041192 0.18789129980041192 1.3121997139332702E-286 cellular_response_to_endogenous_stimulus GO:0071495 12133 704 34 5 982 5 1 false 0.18860492831538925 0.18860492831538925 2.6984349291053464E-253 RNA_export_from_nucleus GO:0006405 12133 72 34 2 165 2 2 false 0.18891352549889404 0.18891352549889404 1.3059643179360761E-48 retina_development_in_camera-type_eye GO:0060041 12133 80 34 1 3099 8 2 false 0.1889863860393375 0.1889863860393375 1.0085113815521168E-160 ephrin_receptor_signaling_pathway GO:0048013 12133 30 34 1 586 4 1 false 0.19003213887065157 0.19003213887065157 5.184030943639595E-51 negative_regulation_of_ion_transport GO:0043271 12133 50 34 1 974 4 3 false 0.19033208156814752 0.19033208156814752 4.081641839466338E-85 Cul4B-RING_ubiquitin_ligase_complex GO:0031465 12133 4 34 1 21 1 1 false 0.19047619047619052 0.19047619047619052 1.6708437761069314E-4 regulation_of_cell_division GO:0051302 12133 75 34 1 6427 18 2 false 0.1906858843792651 0.1906858843792651 9.599183496643589E-177 regulation_of_intracellular_steroid_hormone_receptor_signaling_pathway GO:0033143 12133 43 34 1 1642 8 2 false 0.19164390561601655 0.19164390561601655 5.767987369966462E-86 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 34 7 5447 30 3 false 0.19346491805740768 0.19346491805740768 0.0 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 34 9 6103 32 3 false 0.19490769730043594 0.19490769730043594 0.0 pore_complex GO:0046930 12133 84 34 1 5051 13 3 false 0.19609509039192596 0.19609509039192596 5.4712090537168384E-185 type_I_interferon_production GO:0032606 12133 71 34 1 362 1 1 false 0.19613259668509953 0.19613259668509953 2.8677775679244762E-77 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 34 1 243 3 2 false 0.19628829474170104 0.19628829474170104 1.7559807727942103E-26 positive_regulation_of_cell_division GO:0051781 12133 51 34 1 3061 13 3 false 0.19656058439359403 0.19656058439359403 3.9220691729316426E-112 channel_regulator_activity GO:0016247 12133 66 34 1 10257 34 2 false 0.1973522454760374 0.1973522454760374 1.2576121117294417E-172 protein_phosphorylated_amino_acid_binding GO:0045309 12133 19 34 2 42 2 1 false 0.19860627177700557 0.19860627177700557 2.238261550776809E-12 methyltransferase_complex GO:0034708 12133 62 34 1 9248 33 2 false 0.1993794892840484 0.1993794892840484 4.919625587422917E-161 retinal_cone_cell_development GO:0046549 12133 4 34 1 20 1 2 false 0.20000000000000007 0.20000000000000007 2.063983488132107E-4 postreplication_repair GO:0006301 12133 16 34 1 368 5 1 false 0.20028861513027715 0.20028861513027715 2.574562678585272E-28 RNA_biosynthetic_process GO:0032774 12133 2751 34 21 4191 28 3 false 0.20046651880952016 0.20046651880952016 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 34 8 2595 13 2 false 0.20079293847211643 0.20079293847211643 0.0 regulation_of_peptidyl-serine_phosphorylation GO:0033135 12133 59 34 1 818 3 2 false 0.20137786697215734 0.20137786697215734 1.6613120232447818E-91 muscle_cell_differentiation GO:0042692 12133 267 34 2 2218 7 2 false 0.20206544299836912 0.20206544299836912 0.0 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 34 1 201 1 3 false 0.20398009950248341 0.20398009950248341 9.949481941404742E-44 regulation_of_cell_junction_assembly GO:1901888 12133 35 34 1 1245 8 3 false 0.20449214823455455 0.20449214823455455 7.812749785355693E-69 negative_regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0030512 12133 57 34 2 195 3 4 false 0.2050416438964213 0.2050416438964213 1.081664723883568E-50 anatomical_structure_formation_involved_in_morphogenesis GO:0048646 12133 693 34 3 3447 8 2 false 0.20519604344378842 0.20519604344378842 0.0 regulation_of_type_I_interferon_production GO:0032479 12133 67 34 1 325 1 2 false 0.2061538461538324 0.2061538461538324 2.788484219003069E-71 macromolecule_methylation GO:0043414 12133 149 34 2 5645 32 3 false 0.20636053918664612 0.20636053918664612 2.745935058350772E-298 activation_of_protein_kinase_activity GO:0032147 12133 247 34 3 417 3 1 false 0.20678577619830135 0.20678577619830135 9.475379918718814E-122 pallium_development GO:0021543 12133 89 34 1 3099 8 2 false 0.2081495981101022 0.2081495981101022 1.1299570779339424E-174 mitotic_spindle_organization GO:0007052 12133 37 34 1 648 4 2 false 0.21001217530366648 0.21001217530366648 3.6765869552528886E-61 regulation_of_cell_communication GO:0010646 12133 1796 34 7 6469 18 2 false 0.21003476780003477 0.21003476780003477 0.0 signal_transduction_involved_in_cell_cycle_checkpoint GO:0072395 12133 64 34 1 2474 9 3 false 0.2104349564016206 0.2104349564016206 1.917782059478808E-128 positive_regulation_of_histone_acetylation GO:0035066 12133 16 34 1 144 2 4 false 0.2105672105671897 0.2105672105671897 1.4536629180584386E-21 potassium_ion_transport GO:0006813 12133 115 34 1 545 1 2 false 0.21100917431194127 0.21100917431194127 2.5935886393871475E-121 somatic_diversification_of_immune_receptors GO:0002200 12133 54 34 1 1618 7 2 false 0.2118434834478246 0.2118434834478246 2.9301103973458922E-102 activation_of_innate_immune_response GO:0002218 12133 155 34 3 362 4 2 false 0.21191280677554653 0.21191280677554653 1.0665156090103768E-106 sodium_ion_transmembrane_transporter_activity GO:0015081 12133 67 34 1 316 1 3 false 0.21202531645569045 0.21202531645569045 2.2934303131006308E-70 regulation_of_B_cell_mediated_immunity GO:0002712 12133 30 34 1 140 1 3 false 0.21428571428570842 0.21428571428570842 3.1294479390270554E-31 negative_regulation_of_cytokine_production GO:0001818 12133 114 34 1 529 1 3 false 0.21550094517957671 0.21550094517957671 4.407958658606205E-119 apoptotic_mitochondrial_changes GO:0008637 12133 87 34 1 1476 4 2 false 0.21593368696851734 0.21593368696851734 5.447605955370739E-143 positive_regulation_of_binding GO:0051099 12133 73 34 1 9050 30 3 false 0.21601228864126426 0.21601228864126426 8.738239425278628E-184 negative_regulation_of_type_I_interferon_production GO:0032480 12133 32 34 1 148 1 3 false 0.21621621621620796 0.21621621621620796 3.492638478654734E-33 negative_regulation_of_cysteine-type_endopeptidase_activity GO:2000117 12133 66 34 1 303 1 3 false 0.21782178217821413 0.21782178217821413 1.924144504065005E-68 regulation_of_dephosphorylation GO:0035303 12133 87 34 1 1455 4 2 false 0.2187710435183987 0.2187710435183987 1.9687002630039133E-142 positive_regulation_of_peptidyl-serine_phosphorylation GO:0033138 12133 47 34 1 594 3 3 false 0.21942681797238892 0.21942681797238892 7.186758669481106E-71 positive_regulation_of_ion_transport GO:0043270 12133 86 34 1 1086 3 3 false 0.21943839699604084 0.21943839699604084 6.3756507891276546E-130 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 34 7 3771 24 4 false 0.22180776245811437 0.22180776245811437 0.0 cell_cycle_phase_transition GO:0044770 12133 415 34 3 953 4 1 false 0.22196399820082402 0.22196399820082402 1.4433288987581492E-282 B_cell_activation_involved_in_immune_response GO:0002312 12133 42 34 1 189 1 2 false 0.22222222222221422 0.22222222222221422 4.7631707498717995E-43 regulation_of_protein_acetylation GO:1901983 12133 34 34 1 1097 8 2 false 0.22329358519025533 0.22329358519025533 2.1258425781065562E-65 regulation_of_signaling GO:0023051 12133 1793 34 7 6715 19 2 false 0.22403632332120094 0.22403632332120094 0.0 negative_regulation_of_peptidase_activity GO:0010466 12133 156 34 1 695 1 3 false 0.22446043165470023 0.22446043165470023 5.1885244604442586E-160 negative_regulation_of_catalytic_activity GO:0043086 12133 588 34 3 4970 14 3 false 0.22485201240127484 0.22485201240127484 0.0 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 34 4 1730 7 2 false 0.22543627052985324 0.22543627052985324 0.0 hormone_activity GO:0005179 12133 57 34 1 918 4 1 false 0.2265121970011437 0.2265121970011437 3.1386577853752424E-92 small_conjugating_protein_binding GO:0032182 12133 71 34 1 6397 23 1 false 0.22674628717844578 0.22674628717844578 7.493300865579233E-169 protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:0001844 12133 25 34 1 305 3 3 false 0.226979557317243 0.226979557317243 3.3284741778861134E-37 positive_regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033148 12133 8 34 1 35 1 3 false 0.22857142857142917 0.22857142857142917 4.248842827655879E-8 regulation_of_ERBB_signaling_pathway GO:1901184 12133 61 34 1 1663 7 2 false 0.23054636016567492 0.23054636016567492 5.186655572840897E-113 response_to_fibroblast_growth_factor_stimulus GO:0071774 12133 173 34 2 1130 6 2 false 0.23056623708079244 0.23056623708079244 2.620015602340521E-209 regulation_of_biological_quality GO:0065008 12133 2082 34 8 6908 20 1 false 0.2317015257954848 0.2317015257954848 0.0 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 34 2 835 4 2 false 0.23198904075751892 0.23198904075751892 8.0742416973675315E-196 regulation_of_protein_complex_assembly GO:0043254 12133 185 34 2 1610 8 3 false 0.2320194100788854 0.2320194100788854 1.34790682725651E-248 localization_within_membrane GO:0051668 12133 37 34 1 1845 13 1 false 0.23219796040363846 0.23219796040363846 2.8489513256034824E-78 Cul4-RING_ubiquitin_ligase_complex GO:0080008 12133 21 34 1 90 1 1 false 0.23333333333333656 0.23333333333333656 5.884575201651408E-21 response_to_virus GO:0009615 12133 230 34 2 475 2 1 false 0.23393293359989506 0.23393293359989506 3.548520767075247E-142 protein_complex_localization GO:0031503 12133 29 34 1 1434 13 1 false 0.23411638263600876 0.23411638263600876 3.39152835029198E-61 transmembrane_receptor_protein_serine/threonine_kinase_signaling_pathway GO:0007178 12133 232 34 3 803 6 1 false 0.23481510632085845 0.23481510632085845 7.141936114023743E-209 regulation_of_transferase_activity GO:0051338 12133 667 34 3 2708 7 2 false 0.23576329910108348 0.23576329910108348 0.0 Rho_protein_signal_transduction GO:0007266 12133 178 34 2 365 2 1 false 0.23713683576697228 0.23713683576697228 3.561371803691081E-109 neuron_migration GO:0001764 12133 89 34 1 1360 4 2 false 0.23740814141545258 0.23740814141545258 4.085890514650152E-142 photoreceptor_connecting_cilium GO:0032391 12133 15 34 1 63 1 1 false 0.23809523809523717 0.23809523809523717 8.187880127782087E-15 negative_regulation_of_protein_complex_assembly GO:0031333 12133 63 34 1 954 4 3 false 0.23945713431490256 0.23945713431490256 3.124938390294621E-100 transforming_growth_factor_beta_receptor_signaling_pathway GO:0007179 12133 157 34 3 252 3 2 false 0.24007209258204606 0.24007209258204606 5.925442745937436E-72 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 34 2 522 4 3 false 0.2404304590730289 0.2404304590730289 1.2617392241842968E-123 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 34 7 5032 30 4 false 0.24095427984773238 0.24095427984773238 0.0 regulation_of_protein_catabolic_process GO:0042176 12133 150 34 2 1912 12 3 false 0.2414239288505498 0.2414239288505498 1.3832082048306078E-227 regulation_of_production_of_molecular_mediator_of_immune_response GO:0002700 12133 55 34 1 225 1 2 false 0.24444444444445407 0.24444444444445407 7.316653969426907E-54 regulation_of_Rho_protein_signal_transduction GO:0035023 12133 149 34 2 299 2 2 false 0.24749163879601563 0.24749163879601563 2.1331125641940734E-89 defense_response GO:0006952 12133 1018 34 6 2540 11 1 false 0.24780894732635333 0.24780894732635333 0.0 cell_motility GO:0048870 12133 785 34 3 1249 3 3 false 0.24791568496314978 0.24791568496314978 0.0 regulation_of_B_cell_activation GO:0050864 12133 78 34 1 314 1 2 false 0.24840764331208454 0.24840764331208454 6.891800701996175E-76 RNA_methylation GO:0001510 12133 25 34 1 188 2 2 false 0.24889065877798863 0.24889065877798863 1.1533363650630908E-31 regulation_of_transforming_growth_factor_beta_receptor_signaling_pathway GO:0017015 12133 83 34 2 254 3 3 false 0.24964542475661802 0.24964542475661802 3.7262148804586973E-69 UBC13-MMS2_complex GO:0031372 12133 2 34 1 8 1 1 false 0.24999999999999994 0.24999999999999994 0.035714285714285705 UBC13-UEV1A_complex GO:0035370 12133 2 34 1 8 1 1 false 0.24999999999999994 0.24999999999999994 0.035714285714285705 leukocyte_activation_involved_in_immune_response GO:0002366 12133 119 34 1 475 1 2 false 0.2505263157894802 0.2505263157894802 1.7839978104873963E-115 negative_regulation_of_protein_modification_process GO:0031400 12133 328 34 3 2431 13 3 false 0.25134797800703057 0.25134797800703057 0.0 insulin_receptor_signaling_pathway GO:0008286 12133 151 34 2 617 4 2 false 0.25249877890860667 0.25249877890860667 2.0667953594506098E-148 response_to_peptide_hormone_stimulus GO:0043434 12133 313 34 2 619 2 2 false 0.2552817729818599 0.2552817729818599 1.4916788604957572E-185 positive_regulation_of_histone_H3-K4_methylation GO:0051571 12133 10 34 1 39 1 3 false 0.2564102564102556 0.2564102564102556 1.5729567312509424E-9 regulation_of_peptidyl-lysine_acetylation GO:2000756 12133 33 34 1 128 1 2 false 0.25781249999999833 0.25781249999999833 2.3260819461485724E-31 mitochondrial_outer_membrane GO:0005741 12133 96 34 1 372 1 2 false 0.25806451612902936 0.25806451612902936 1.1824719222700171E-91 midbody GO:0030496 12133 90 34 1 9983 33 1 false 0.2586905575008742 0.2586905575008742 2.5893666131724343E-222 regulation_of_transporter_activity GO:0032409 12133 88 34 1 2973 10 3 false 0.25986978035415326 0.25986978035415326 1.555650039308817E-171 regulation_of_phosphorylation GO:0042325 12133 845 34 3 1820 4 2 false 0.26069661167854885 0.26069661167854885 0.0 mRNA_binding GO:0003729 12133 91 34 3 763 15 1 false 0.2613900554784836 0.2613900554784836 1.7788235024198917E-120 transferase_activity,_transferring_one-carbon_groups GO:0016741 12133 130 34 1 1779 4 1 false 0.26198838129502205 0.26198838129502205 2.4341608753326182E-201 positive_regulation_of_DNA_repair GO:0045739 12133 26 34 1 440 5 4 false 0.26359953522455065 0.26359953522455065 1.5959457492821637E-42 protein_export_from_nucleus GO:0006611 12133 46 34 1 2428 16 3 false 0.2643471902064889 0.2643471902064889 1.6048237175829586E-98 regulation_of_innate_immune_response GO:0045088 12133 226 34 3 868 7 3 false 0.2648651863447815 0.2648651863447815 2.196344369914344E-215 histone_methyltransferase_complex GO:0035097 12133 60 34 1 807 4 2 false 0.26628375978369023 0.26628375978369023 3.052234764972827E-92 immune_system_process GO:0002376 12133 1618 34 7 10446 34 1 false 0.2672261581199632 0.2672261581199632 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway_involved_in_phagocytosis GO:0002433 12133 72 34 1 500 2 2 false 0.2675110220441193 0.2675110220441193 6.2427882790248544E-89 centriole GO:0005814 12133 53 34 1 3226 19 3 false 0.2706727163877525 0.2706727163877525 7.215034471949268E-117 regulation_of_defense_response GO:0031347 12133 387 34 3 1253 6 2 false 0.27192134241257254 0.27192134241257254 0.0 metaphase/anaphase_transition_of_mitotic_cell_cycle GO:0007091 12133 45 34 1 591 4 3 false 0.27212674677647325 0.27212674677647325 1.267222544612779E-68 U7_snRNP GO:0005683 12133 7 34 1 93 4 1 false 0.27268913103415005 0.27268913103415005 1.0555624376114707E-10 peptidyl-serine_phosphorylation GO:0018105 12133 121 34 1 1201 3 2 false 0.27302324515508136 0.27302324515508136 1.0029038835537004E-169 cellular_process GO:0009987 12133 9675 34 33 10446 34 1 false 0.2731267779961162 0.2731267779961162 0.0 histone_deacetylase_binding GO:0042826 12133 62 34 1 1005 5 1 false 0.27315273897610554 0.27315273897610554 1.577479125629217E-100 positive_regulation_of_cell_cycle_arrest GO:0071158 12133 76 34 1 278 1 3 false 0.27338129496405167 0.27338129496405167 2.8121052478162137E-70 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 34 3 2776 8 3 false 0.27356830198766713 0.27356830198766713 0.0 cellular_potassium_ion_transport GO:0071804 12133 92 34 1 7541 26 2 false 0.27362117315872114 0.27362117315872114 4.105440908779901E-215 vesicle_membrane GO:0012506 12133 312 34 2 9991 33 4 false 0.27561864528318736 0.27561864528318736 0.0 regulation_of_muscle_tissue_development GO:1901861 12133 105 34 1 1351 4 2 false 0.2767508309348755 0.2767508309348755 1.3105194568745759E-159 mRNA_3'-splice_site_recognition GO:0000389 12133 5 34 1 18 1 1 false 0.2777777777777786 0.2777777777777786 1.1671335200746984E-4 fibroblast_growth_factor_receptor_signaling_pathway GO:0008543 12133 156 34 2 599 4 2 false 0.27912889848581784 0.27912889848581784 1.7219296535416308E-148 positive_regulation_of_nucleotide_metabolic_process GO:0045981 12133 83 34 1 2578 10 4 false 0.27951730930985524 0.27951730930985524 1.0942419479084622E-158 spindle_pole GO:0000922 12133 87 34 1 3232 12 3 false 0.27964653785511595 0.27964653785511595 3.214023535487519E-173 regulation_of_mitotic_cell_cycle_phase_transition GO:1901990 12133 177 34 2 506 3 3 false 0.2810733247237542 0.2810733247237542 1.5079927652081954E-141 cell_cycle GO:0007049 12133 1295 34 6 7541 26 1 false 0.2813154144815323 0.2813154144815323 0.0 positive_regulation_of_purine_nucleotide_biosynthetic_process GO:1900373 12133 77 34 1 273 1 4 false 0.2820512820512513 0.2820512820512513 5.5014514459438226E-70 blood_vessel_morphogenesis GO:0048514 12133 368 34 2 2812 8 3 false 0.28213602715768804 0.28213602715768804 0.0 muscle_structure_development GO:0061061 12133 413 34 2 3152 8 2 false 0.28264784200908644 0.28264784200908644 0.0 mitotic_DNA_damage_checkpoint GO:0044773 12133 76 34 1 953 4 3 false 0.2832144956587193 0.2832144956587193 1.5807807987211998E-114 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 34 2 650 4 2 false 0.28368765102059623 0.28368765102059623 6.010278185218431E-162 positive_regulation_of_cytokine_production GO:0001819 12133 175 34 1 614 1 3 false 0.2850162866449984 0.2850162866449984 1.2195240299259301E-158 mRNA_splice_site_selection GO:0006376 12133 18 34 1 117 2 2 false 0.2851458885941616 0.2851458885941616 1.505085052005422E-21 positive_regulation_of_histone_methylation GO:0031062 12133 16 34 1 104 2 3 false 0.28528752800596324 0.28528752800596324 3.7681406369703167E-19 protein_insertion_into_membrane GO:0051205 12133 32 34 1 1452 15 3 false 0.2853171057895226 0.2853171057895226 2.4360077014496946E-66 regulation_of_programmed_cell_death GO:0043067 12133 1031 34 4 1410 4 2 false 0.28541547821161944 0.28541547821161944 0.0 cilium_part GO:0044441 12133 69 34 1 5535 27 4 false 0.2878765645899842 0.2878765645899842 1.3900483239048332E-160 positive_regulation_of_nucleotide_biosynthetic_process GO:0030810 12133 77 34 1 1402 6 4 false 0.28790746185077565 0.28790746185077565 6.104501177954134E-129 positive_regulation_of_lyase_activity GO:0051349 12133 64 34 1 1165 6 3 false 0.2880618577839109 0.2880618577839109 4.208539259642897E-107 enzyme_binding GO:0019899 12133 1005 34 5 6397 23 1 false 0.28880357910796095 0.28880357910796095 0.0 DNA_metabolic_process GO:0006259 12133 791 34 6 5627 32 2 false 0.28934517200689597 0.28934517200689597 0.0 negative_regulation_of_mitotic_cell_cycle_phase_transition GO:1901991 12133 148 34 2 415 3 3 false 0.29035582270131366 0.29035582270131366 9.462933237946419E-117 regulation_of_protein_binding GO:0043393 12133 95 34 1 6398 23 2 false 0.29154676892212256 0.29154676892212256 5.5524328548337306E-214 metaphase/anaphase_transition_of_cell_cycle GO:0044784 12133 45 34 1 415 3 1 false 0.29192800256720985 0.29192800256720985 2.1919403735850567E-61 potassium_ion_transmembrane_transporter_activity GO:0015079 12133 92 34 1 315 1 3 false 0.2920634920635222 0.2920634920635222 4.7759735730125735E-82 maintenance_of_location_in_cell GO:0051651 12133 100 34 1 7542 26 3 false 0.2936344131730074 0.2936344131730074 3.2184799576057033E-230 mitochondrial_membrane_organization GO:0007006 12133 62 34 1 924 5 2 false 0.29394705415663247 0.29394705415663247 3.431124286579491E-98 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 34 3 305 4 2 false 0.29419348391070643 0.29419348391070643 3.640759676212702E-91 regulation_of_cell_cycle GO:0051726 12133 659 34 3 6583 19 2 false 0.2950466754351121 0.2950466754351121 0.0 smooth_muscle_contraction GO:0006939 12133 65 34 1 220 1 1 false 0.29545454545454364 0.29545454545454364 1.7294918023527772E-57 regulation_of_apoptotic_process GO:0042981 12133 1019 34 4 1381 4 2 false 0.2959718275434151 0.2959718275434151 0.0 histone_ubiquitination GO:0016574 12133 31 34 1 813 9 2 false 0.2964773886028153 0.2964773886028153 8.990376944152675E-57 negative_regulation_of_cell_cycle_process GO:0010948 12133 246 34 2 2943 13 3 false 0.2972830186162922 0.2972830186162922 0.0 negative_regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902100 12133 36 34 1 222 2 3 false 0.29864253393661766 0.29864253393661766 2.5456303013282065E-42 microtubule_organizing_center_part GO:0044450 12133 84 34 1 5487 23 3 false 0.2992098589712138 0.2992098589712138 4.9382557339234635E-188 positive_regulation_of_mitochondrion_organization GO:0010822 12133 43 34 1 385 3 3 false 0.2997249160761194 0.2997249160761194 4.6200993055738E-58 cyclase_activity GO:0009975 12133 123 34 1 4901 14 1 false 0.2997514361667514 0.2997514361667514 7.077862449152851E-249 retinal_rod_cell_development GO:0046548 12133 6 34 1 20 1 1 false 0.30000000000000027 0.30000000000000027 2.5799793601651193E-5 tissue_migration GO:0090130 12133 131 34 1 4095 11 1 false 0.3009889596789227 0.3009889596789227 4.3202440607580954E-251 regulation_of_metal_ion_transport GO:0010959 12133 159 34 1 527 1 2 false 0.30170777988610137 0.30170777988610137 1.9143009234930405E-139 negative_regulation_of_transport GO:0051051 12133 243 34 2 4618 21 3 false 0.30382635317397577 0.30382635317397577 0.0 transcription_coactivator_activity GO:0003713 12133 264 34 2 478 2 2 false 0.30451830215001674 0.30451830215001674 4.798051856605128E-142 viral_protein_processing GO:0019082 12133 10 34 1 256 9 2 false 0.30542984642063725 0.30542984642063725 3.5864633505920636E-18 nucleobase-containing_compound_transport GO:0015931 12133 135 34 2 1584 13 2 false 0.30549668223352033 0.30549668223352033 1.0378441909200412E-199 regulation_of_skeletal_muscle_tissue_development GO:0048641 12133 63 34 1 206 1 2 false 0.3058252427184593 0.3058252427184593 1.364605297408496E-54 anaphase-promoting_complex-dependent_proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0031145 12133 81 34 2 220 3 1 false 0.3060084316839271 0.3060084316839271 2.4407604211478482E-62 regulation_of_leukocyte_mediated_immunity GO:0002703 12133 84 34 1 274 1 2 false 0.30656934306567774 0.30656934306567774 8.733942624679482E-73 negative_regulation_of_cellular_protein_metabolic_process GO:0032269 12133 422 34 4 3605 24 4 false 0.30688439164457687 0.30688439164457687 0.0 positive_regulation_of_cyclase_activity GO:0031281 12133 63 34 1 1064 6 3 false 0.3072636368739998 0.3072636368739998 2.5891490792503797E-103 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 34 3 639 4 3 false 0.30839252562688757 0.30839252562688757 1.399157780258238E-191 RNA_localization GO:0006403 12133 131 34 2 1642 14 1 false 0.3088491702888986 0.3088491702888986 1.0675246049472868E-197 mitochondrial_outer_membrane_permeabilization GO:0097345 12133 37 34 1 319 3 3 false 0.3100201715862682 0.3100201715862682 2.7662883808425E-49 telencephalon_development GO:0021537 12133 141 34 1 3099 8 2 false 0.31130743456702464 0.31130743456702464 2.6342742970069075E-248 mitotic_cell_cycle GO:0000278 12133 625 34 4 1295 6 1 false 0.31135396305509383 0.31135396305509383 0.0 cellular_response_to_peptide_hormone_stimulus GO:0071375 12133 247 34 2 442 2 3 false 0.3117246898760163 0.3117246898760163 4.945935388068452E-131 regulation_of_DNA_recombination GO:0000018 12133 38 34 1 324 3 2 false 0.31304889105398015 0.31304889105398015 1.9894741609704344E-50 poly(A)_RNA_binding GO:0008143 12133 11 34 1 94 3 2 false 0.31454596998000534 0.31454596998000534 1.4483869139240058E-14 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 34 2 53 2 2 false 0.31567489114658837 0.31567489114658837 1.6040955778771873E-15 epithelial_cell_development GO:0002064 12133 164 34 1 1381 3 2 false 0.31583098782937874 0.31583098782937874 8.032286414365126E-218 positive_regulation_of_endocytosis GO:0045807 12133 63 34 1 1023 6 4 false 0.31773334593481944 0.31773334593481944 3.3235317732048763E-102 protein_K48-linked_ubiquitination GO:0070936 12133 37 34 2 163 5 1 false 0.3181322846120346 0.3181322846120346 1.6289154422281443E-37 sodium_ion_transmembrane_transport GO:0035725 12133 68 34 1 565 3 2 false 0.31984590445849154 0.31984590445849154 1.2033655972436562E-89 cell-cell_junction_assembly GO:0007043 12133 58 34 1 181 1 2 false 0.3204419889502846 0.3204419889502846 7.851737058026464E-49 negative_regulation_of_endopeptidase_activity GO:0010951 12133 152 34 1 474 1 3 false 0.3206751054852057 0.3206751054852057 1.8080345918982332E-128 immunoglobulin_production_involved_in_immunoglobulin_mediated_immune_response GO:0002381 12133 37 34 1 115 1 2 false 0.3217391304347844 0.3217391304347844 5.328533934457324E-31 regulation_of_immunoglobulin_mediated_immune_response GO:0002889 12133 29 34 1 90 1 2 false 0.322222222222227 0.322222222222227 3.0207008278323007E-24 proteolysis GO:0006508 12133 732 34 6 3431 22 1 false 0.32245667463879446 0.32245667463879446 0.0 single-stranded_DNA_binding GO:0003697 12133 58 34 1 179 1 1 false 0.32402234636869975 0.32402234636869975 1.7047154028422047E-48 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 34 9 7638 32 4 false 0.3244252261144762 0.3244252261144762 0.0 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 34 2 207 3 2 false 0.32496096256869944 0.32496096256869944 2.976076769798144E-59 regulation_of_immunoglobulin_production GO:0002637 12133 29 34 1 89 1 2 false 0.32584269662921084 0.32584269662921084 4.456771713195185E-24 positive_regulation_of_cell_cycle GO:0045787 12133 98 34 1 3492 14 3 false 0.3291911298817607 0.3291911298817607 2.23767062140918E-193 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 34 7 3631 27 4 false 0.3298335806644024 0.3298335806644024 0.0 regulation_of_metaphase/anaphase_transition_of_cell_cycle GO:1902099 12133 44 34 1 242 2 2 false 0.3311957751791627 0.3311957751791627 2.220259827778367E-49 organelle_outer_membrane GO:0031968 12133 110 34 1 9084 33 4 false 0.33152550112038814 0.33152550112038814 1.1973077012984011E-257 kinesin_complex GO:0005871 12133 20 34 1 110 2 1 false 0.33194328607172413 0.33194328607172413 2.27584542759169E-22 signaling_adaptor_activity GO:0035591 12133 65 34 1 839 5 2 false 0.3324886297435495 0.3324886297435495 9.48818477040309E-99 regulation_of_lyase_activity GO:0051339 12133 117 34 1 1793 6 2 false 0.3333341997274487 0.3333341997274487 4.0773224530305873E-187 ncRNA_metabolic_process GO:0034660 12133 258 34 3 3294 26 1 false 0.3333979180503263 0.3333979180503263 0.0 response_to_ionizing_radiation GO:0010212 12133 98 34 1 293 1 1 false 0.3344709897611002 0.3344709897611002 1.6270830108212225E-80 regulation_of_cell_cycle_arrest GO:0071156 12133 89 34 1 481 2 2 false 0.33613998614007884 0.33613998614007884 1.91357850692127E-99 negative_regulation_of_protein_metabolic_process GO:0051248 12133 478 34 4 3910 24 3 false 0.3365291441233711 0.3365291441233711 0.0 camera-type_eye_morphogenesis GO:0048593 12133 72 34 1 213 1 2 false 0.3380281690140883 0.3380281690140883 1.152774729601503E-58 viral_assembly,_maturation,_egress,_and_release GO:0019067 12133 16 34 1 557 14 2 false 0.3383085836876958 0.3383085836876958 3.0295698614548545E-31 Notch_signaling_pathway GO:0007219 12133 113 34 1 1975 7 1 false 0.3383822343359653 0.3383822343359653 2.33429872590278E-187 protein_binding GO:0005515 12133 6397 34 23 8962 30 1 false 0.3392383988809772 0.3392383988809772 0.0 regulation_of_histone_acetylation GO:0035065 12133 31 34 1 166 2 3 false 0.3395399780942128 0.3395399780942128 2.4571391045681945E-34 coagulation GO:0050817 12133 446 34 2 4095 11 1 false 0.34062070814714973 0.34062070814714973 0.0 protein_serine/threonine_kinase_activity GO:0004674 12133 709 34 3 1014 3 1 false 0.3414058777627787 0.3414058777627787 1.8231541307779663E-268 RNA_modification GO:0009451 12133 64 34 1 4775 31 2 false 0.34271374757322204 0.34271374757322204 6.812362595459872E-147 response_to_cytokine_stimulus GO:0034097 12133 461 34 3 1783 8 1 false 0.34274496240523666 0.34274496240523666 0.0 production_of_molecular_mediator_of_immune_response GO:0002440 12133 94 34 1 1618 7 1 false 0.3428015739409229 0.3428015739409229 3.880703619863946E-155 regulation_of_apoptotic_signaling_pathway GO:2001233 12133 112 34 1 2191 8 3 false 0.34325436206208215 0.34325436206208215 2.495063769189982E-191 regulation_of_cyclase_activity GO:0031279 12133 115 34 1 1700 6 2 false 0.34354733497930623 0.34354733497930623 4.764508019192963E-182 protein_binding,_bridging GO:0030674 12133 116 34 1 6397 23 2 false 0.3440236058811129 0.3440236058811129 3.1111419589573665E-251 positive_regulation_of_purine_nucleotide_metabolic_process GO:1900544 12133 82 34 1 1209 6 3 false 0.3444702493631746 0.3444702493631746 1.376514335843937E-129 regulation_of_cell_death GO:0010941 12133 1062 34 4 6437 18 2 false 0.34466019266697123 0.34466019266697123 0.0 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 34 3 3702 12 3 false 0.3446716615531221 0.3446716615531221 0.0 cellular_response_to_fibroblast_growth_factor_stimulus GO:0044344 12133 172 34 2 859 6 3 false 0.34521303752135896 0.34521303752135896 4.662302019201105E-186 regulation_of_mitotic_metaphase/anaphase_transition GO:0030071 12133 44 34 1 230 2 4 false 0.3466869185493838 0.3466869185493838 2.6271911283291635E-48 RNA_stabilization GO:0043489 12133 22 34 2 37 2 1 false 0.3468468468468479 0.3468468468468479 1.0678969112465738E-10 catalytic_step_2_spliceosome GO:0071013 12133 76 34 4 151 6 3 false 0.34687528062474104 0.34687528062474104 5.422089502503699E-45 organelle_fission GO:0048285 12133 351 34 2 2031 7 1 false 0.34753857345024636 0.34753857345024636 0.0 poly-purine_tract_binding GO:0070717 12133 14 34 1 40 1 1 false 0.3500000000000021 0.3500000000000021 4.309057712047628E-11 steroid_hormone_receptor_binding GO:0035258 12133 62 34 2 104 2 1 false 0.3530619865571091 0.3530619865571091 4.2931773052216616E-30 binding,_bridging GO:0060090 12133 129 34 1 8962 30 1 false 0.3531699530422018 0.3531699530422018 1.7318913122999068E-292 small_molecule_metabolic_process GO:0044281 12133 2423 34 6 2877 6 1 false 0.356497472610474 0.356497472610474 0.0 regulation_of_molecular_function GO:0065009 12133 2079 34 8 10494 34 2 false 0.35666984683630065 0.35666984683630065 0.0 regulation_of_intracellular_estrogen_receptor_signaling_pathway GO:0033146 12133 20 34 1 56 1 2 false 0.35714285714286187 0.35714285714286187 1.2728904491493287E-15 negative_regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042059 12133 39 34 1 197 2 3 false 0.35755723609237877 0.35755723609237877 3.777320475653026E-42 wound_healing GO:0042060 12133 543 34 2 905 2 1 false 0.3597345132743657 0.3597345132743657 1.120707554751266E-263 negative_regulation_of_protein_ubiquitination GO:0031397 12133 95 34 2 759 10 3 false 0.3620603806700141 0.3620603806700141 1.1458874617943115E-123 regulation_of_histone_H3-K4_methylation GO:0051569 12133 16 34 1 44 1 2 false 0.3636363636363643 0.3636363636363643 2.3997227499672215E-12 organ_development GO:0048513 12133 1929 34 6 3099 8 2 false 0.36379681977730866 0.36379681977730866 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity GO:0051444 12133 71 34 2 341 6 4 false 0.36495732524698055 0.36495732524698055 3.257446469032824E-75 peptidyl-serine_modification GO:0018209 12133 127 34 1 623 2 1 false 0.366409810428807 0.366409810428807 3.781982241942545E-136 regulation_of_striated_muscle_tissue_development GO:0016202 12133 105 34 1 286 1 3 false 0.36713286713287985 0.36713286713287985 4.516187028693684E-81 cytokine-mediated_signaling_pathway GO:0019221 12133 318 34 2 2013 8 2 false 0.36810601625343176 0.36810601625343176 0.0 mitotic_cell_cycle_phase_transition GO:0044772 12133 361 34 3 673 4 2 false 0.36852591405447754 0.36852591405447754 4.9348138289436974E-201 kidney_development GO:0001822 12133 161 34 1 2877 8 3 false 0.3695244806360367 0.3695244806360367 9.385342690705625E-269 regulation_of_metabolic_process GO:0019222 12133 4469 34 17 9189 32 2 false 0.36970190724669655 0.36970190724669655 0.0 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 34 9 645 9 1 false 0.3702345386862288 0.3702345386862288 7.3138241320053254E-93 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 34 7 5558 29 3 false 0.37039278558006405 0.37039278558006405 0.0 regulation_of_histone_methylation GO:0031060 12133 27 34 1 130 2 2 false 0.3735241502683365 0.3735241502683365 1.667447080919269E-28 positive_regulation_of_protein_complex_assembly GO:0031334 12133 94 34 1 1054 5 3 false 0.3737489855731968 0.3737489855731968 5.573854633657796E-137 mitotic_cell_cycle_checkpoint GO:0007093 12133 133 34 2 217 2 2 false 0.37455197132611834 0.37455197132611834 2.2668758893633536E-62 maintenance_of_protein_localization_in_organelle GO:0072595 12133 21 34 1 549 12 2 false 0.37679298114498966 0.37679298114498966 2.215926939206221E-38 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 34 16 8688 32 3 false 0.37806210251073397 0.37806210251073397 0.0 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 34 3 1398 8 2 false 0.37817550442676395 0.37817550442676395 0.0 regulation_of_DNA_repair GO:0006282 12133 46 34 1 508 5 3 false 0.3790812233625401 0.3790812233625401 1.525242689490639E-66 nuclear_pore GO:0005643 12133 69 34 1 2781 19 3 false 0.380555013195833 0.380555013195833 8.971129873692015E-140 cytoplasmic_vesicle_membrane GO:0030659 12133 302 34 2 719 3 3 false 0.38090155538138976 0.38090155538138976 1.2351303462379864E-211 SH3/SH2_adaptor_activity GO:0005070 12133 48 34 1 126 1 2 false 0.38095238095239137 0.38095238095239137 5.926155314091347E-36 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 34 2 3842 12 3 false 0.382534462307517 0.382534462307517 0.0 small_ribosomal_subunit GO:0015935 12133 60 34 5 132 9 1 false 0.38590715531712744 0.38590715531712744 4.556510204279982E-39 negative_regulation_of_cell_death GO:0060548 12133 567 34 3 3054 12 3 false 0.39051844597663804 0.39051844597663804 0.0 endosome_membrane GO:0010008 12133 248 34 1 1627 3 2 false 0.39132429913140065 0.39132429913140065 8.244139595488818E-301 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 34 2 1256 14 1 false 0.39279420467025683 0.39279420467025683 3.1457660386089413E-171 intracellular_organelle GO:0043229 12133 7958 34 30 9096 33 2 false 0.3940534268241989 0.3940534268241989 0.0 regulation_of_tube_size GO:0035150 12133 101 34 1 256 1 1 false 0.39453124999999944 0.39453124999999944 5.262447585157191E-74 negative_regulation_of_mitotic_metaphase/anaphase_transition GO:0045841 12133 36 34 1 162 2 5 false 0.39613526570044455 0.39613526570044455 7.1760328941400225E-37 spindle_checkpoint GO:0031577 12133 45 34 1 202 2 1 false 0.3967784838184953 0.3967784838184953 4.3818533729449334E-46 regulation_of_transmembrane_transport GO:0034762 12133 183 34 1 6614 18 3 false 0.39692496686528844 0.39692496686528844 0.0 cell_activation GO:0001775 12133 656 34 3 7541 26 1 false 0.39696304276732225 0.39696304276732225 0.0 B_cell_activation GO:0042113 12133 160 34 1 403 1 1 false 0.3970223325061876 0.3970223325061876 6.533922499780693E-117 nucleoside_phosphate_binding GO:1901265 12133 1998 34 12 4407 24 2 false 0.39754301920367663 0.39754301920367663 0.0 intrinsic_apoptotic_signaling_pathway_in_response_to_DNA_damage GO:0008630 12133 45 34 1 647 7 2 false 0.3977394731565038 0.3977394731565038 1.851108938674389E-70 protein_alkylation GO:0008213 12133 98 34 1 2370 12 1 false 0.3982773356559007 0.3982773356559007 1.3558052911433636E-176 regulation_of_lymphocyte_mediated_immunity GO:0002706 12133 63 34 1 158 1 2 false 0.39873417721520893 0.39873417721520893 1.105088874754345E-45 regulation_of_mitochondrion_organization GO:0010821 12133 64 34 1 661 5 2 false 0.39999257858682696 0.39999257858682696 9.542606350434685E-91 positive_regulation_of_adenylate_cyclase_activity GO:0045762 12133 52 34 1 130 1 5 false 0.3999999999999939 0.3999999999999939 1.4124265749856537E-37 regulation_of_cysteine-type_endopeptidase_activity_involved_in_apoptotic_process GO:0043281 12133 165 34 1 1376 4 3 false 0.4004238534947472 0.4004238534947472 2.059495184181185E-218 protein_complex_subunit_organization GO:0071822 12133 989 34 12 1256 14 1 false 0.40093703292636573 0.40093703292636573 2.2763776011987297E-281 cilium GO:0005929 12133 161 34 1 7595 24 2 false 0.40250789158592587 0.40250789158592587 0.0 protein_sumoylation GO:0016925 12133 32 34 1 578 9 1 false 0.40326468565569495 0.40326468565569495 2.618927943730716E-53 skeletal_muscle_cell_differentiation GO:0035914 12133 57 34 1 251 2 2 false 0.40331474103583304 0.40331474103583304 6.638453930425573E-58 protein_heterodimerization_activity GO:0046982 12133 317 34 1 779 1 1 false 0.4069319640564945 0.4069319640564945 8.49214053182804E-228 regulation_of_body_fluid_levels GO:0050878 12133 527 34 2 4595 12 2 false 0.4079344749889971 0.4079344749889971 0.0 renal_system_development GO:0072001 12133 196 34 1 2686 7 2 false 0.4119887302240636 0.4119887302240636 5.871867151923005E-304 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 34 2 2035 9 3 false 0.4121658775349517 0.4121658775349517 0.0 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 34 7 3547 11 1 false 0.414947680086176 0.414947680086176 0.0 cysteine-type_endopeptidase_activity GO:0004197 12133 219 34 1 527 1 2 false 0.4155597722959447 0.4155597722959447 1.229090165658057E-154 regulation_of_mitosis GO:0007088 12133 100 34 1 611 3 4 false 0.4155861217792173 0.4155861217792173 1.2375244614825155E-117 structure-specific_DNA_binding GO:0043566 12133 179 34 1 2091 6 1 false 0.4158680952484739 0.4158680952484739 1.2928223396172998E-264 BMP_signaling_pathway GO:0030509 12133 83 34 1 1276 8 2 false 0.4170216462988615 0.4170216462988615 9.874891335860256E-133 regulation_of_cell_cycle_phase_transition GO:1901987 12133 241 34 2 541 3 2 false 0.41838125492735057 0.41838125492735057 1.01164377942614E-160 ERBB_signaling_pathway GO:0038127 12133 199 34 2 586 4 1 false 0.41855837078601515 0.41855837078601515 2.435227003721618E-162 regulation_of_Ras_protein_signal_transduction GO:0046578 12133 270 34 2 417 2 2 false 0.41868428334271485 0.41868428334271485 7.174398789465976E-117 ribonucleoprotein_granule GO:0035770 12133 75 34 1 3365 24 2 false 0.41890916169435644 0.41890916169435644 1.704323678285534E-155 potassium_ion_transmembrane_transport GO:0071805 12133 92 34 1 556 3 2 false 0.41941821311218713 0.41941821311218713 1.0312185181817459E-107 cytoplasmic_membrane-bounded_vesicle GO:0016023 12133 712 34 3 7293 24 3 false 0.420019604449028 0.420019604449028 0.0 protein_autoubiquitination GO:0051865 12133 32 34 1 548 9 1 false 0.42052610492975834 0.42052610492975834 1.513679138085879E-52 ubiquitin-protein_ligase_activity GO:0004842 12133 321 34 6 558 9 2 false 0.42053757617403387 0.42053757617403387 1.7708856343357755E-164 cell_cycle_process GO:0022402 12133 953 34 4 7541 26 2 false 0.4206857968754548 0.4206857968754548 0.0 signal_transduction GO:0007165 12133 3547 34 11 6702 19 4 false 0.4210477878585567 0.4210477878585567 0.0 regulation_of_peptidase_activity GO:0052547 12133 276 34 1 1151 2 2 false 0.42224152910517165 0.42224152910517165 1.6233323078676786E-274 negative_regulation_of_blood_pressure GO:0045776 12133 28 34 1 117 2 1 false 0.4229295608605921 0.4229295608605921 1.267799191286988E-27 mitosis GO:0007067 12133 326 34 2 953 4 2 false 0.42297457478432593 0.42297457478432593 4.8424843971573165E-265 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 34 5 2771 16 5 false 0.4238056899375712 0.4238056899375712 0.0 regulation_of_actin_filament-based_process GO:0032970 12133 192 34 1 6365 18 2 false 0.4242468324936032 0.4242468324936032 0.0 receptor_binding GO:0005102 12133 918 34 4 6397 23 1 false 0.42480113515261037 0.42480113515261037 0.0 negative_regulation_of_cell_cycle GO:0045786 12133 298 34 2 3131 15 3 false 0.4252374329689608 0.4252374329689608 0.0 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 34 10 6129 32 3 false 0.4261092989641597 0.4261092989641597 0.0 protein_kinase_activity GO:0004672 12133 1014 34 3 1347 3 3 false 0.4262780524274708 0.4262780524274708 0.0 anatomical_structure_development GO:0048856 12133 3099 34 8 3447 8 1 false 0.4264278743994168 0.4264278743994168 0.0 regulation_of_adaptive_immune_response_based_on_somatic_recombination_of_immune_receptors_built_from_immunoglobulin_superfamily_domains GO:0002822 12133 70 34 1 163 1 2 false 0.42944785276073405 0.42944785276073405 6.913027082032024E-48 transcription_factor_binding_transcription_factor_activity GO:0000989 12133 474 34 2 723 2 2 false 0.42950081033556575 0.42950081033556575 2.0953844092707462E-201 dynein_complex GO:0030286 12133 27 34 1 110 2 1 false 0.43236030025020594 0.43236030025020594 2.7050159623675944E-26 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 34 6 4429 25 3 false 0.432418716918191 0.432418716918191 0.0 GTP_binding GO:0005525 12133 292 34 2 1635 8 3 false 0.4325342213188544 0.4325342213188544 0.0 histone_methylation GO:0016571 12133 80 34 1 324 2 2 false 0.4334365325077039 0.4334365325077039 4.398247108446164E-78 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 34 3 309 4 2 false 0.43352496749598646 0.43352496749598646 7.558729588417702E-91 cyclic_nucleotide_biosynthetic_process GO:0009190 12133 151 34 1 348 1 2 false 0.4339080459770588 0.4339080459770588 8.533554981861938E-103 regulation_of_nucleotide_biosynthetic_process GO:0030808 12133 146 34 1 3406 13 3 false 0.4348003339223552 0.4348003339223552 5.390613252169377E-261 regulation_of_binding GO:0051098 12133 172 34 1 9142 30 2 false 0.43488130995230945 0.43488130995230945 0.0 protein_C-terminus_binding GO:0008022 12133 157 34 1 6397 23 1 false 0.43589972900572194 0.43589972900572194 2.34014E-319 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 34 7 5151 29 4 false 0.4360237849419186 0.4360237849419186 0.0 cAMP_biosynthetic_process GO:0006171 12133 124 34 1 284 1 3 false 0.4366197183098948 0.4366197183098948 6.647675853046176E-84 mRNA_stabilization GO:0048255 12133 22 34 2 33 2 2 false 0.43750000000000067 0.43750000000000067 5.166978132108427E-9 kinase_activity GO:0016301 12133 1174 34 3 1546 3 2 false 0.437631376164805 0.437631376164805 0.0 double-strand_break_repair_via_homologous_recombination GO:0000724 12133 48 34 1 109 1 2 false 0.4403669724770689 0.4403669724770689 4.364037891784993E-32 ameboidal_cell_migration GO:0001667 12133 185 34 1 734 2 1 false 0.4408184051951548 0.4408184051951548 3.1688746703355204E-179 rRNA_processing GO:0006364 12133 102 34 1 231 1 3 false 0.4415584415584419 0.4415584415584419 2.6685808966337758E-68 response_to_salt_stress GO:0009651 12133 19 34 1 43 1 1 false 0.44186046511627686 0.44186046511627686 1.2492622608986976E-12 actin_filament-based_process GO:0030029 12133 431 34 2 7541 26 1 false 0.4425351332264051 0.4425351332264051 0.0 rRNA_binding GO:0019843 12133 29 34 1 763 15 1 false 0.4438645576682872 0.4438645576682872 3.8668021308986908E-53 negative_regulation_of_molecular_function GO:0044092 12133 735 34 3 10257 34 2 false 0.4441144936017277 0.4441144936017277 0.0 regulation_of_purine_nucleotide_biosynthetic_process GO:1900371 12133 146 34 1 574 2 3 false 0.4443451240795597 0.4443451240795597 1.1371703790830463E-140 positive_regulation_of_cyclic_nucleotide_metabolic_process GO:0030801 12133 80 34 1 180 1 3 false 0.44444444444442294 0.44444444444442294 3.3247573319336413E-53 ATPase_activity GO:0016887 12133 307 34 2 1069 5 2 false 0.44540128214072716 0.44540128214072716 1.5605649392254874E-277 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 34 6 4298 25 4 false 0.44793023944968624 0.44793023944968624 0.0 cellular_response_to_insulin_stimulus GO:0032869 12133 185 34 2 276 2 2 false 0.44848484848485837 0.44848484848485837 1.999097443178639E-75 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 34 6 504 7 1 false 0.44868112794403103 0.44868112794403103 6.011520399617331E-122 positive_regulation_of_lymphocyte_activation GO:0051251 12133 188 34 1 419 1 3 false 0.44868735083532396 0.44868735083532396 1.71987955515036E-124 regulation_of_skeletal_muscle_cell_differentiation GO:2001014 12133 27 34 1 105 2 3 false 0.4499999999999779 0.4499999999999779 1.1402717682449654E-25 cell_division GO:0051301 12133 438 34 2 7541 26 1 false 0.4509143024771871 0.4509143024771871 0.0 regulation_of_membrane_potential GO:0042391 12133 216 34 1 478 1 1 false 0.4518828451882676 0.4518828451882676 3.2092050959317294E-142 small_GTPase_mediated_signal_transduction GO:0007264 12133 547 34 3 1813 8 1 false 0.4526479922513794 0.4526479922513794 0.0 regulation_of_catalytic_activity GO:0050790 12133 1692 34 6 6953 22 3 false 0.453985130042606 0.453985130042606 0.0 protein_localization GO:0008104 12133 1434 34 13 1642 14 1 false 0.4540950787017209 0.4540950787017209 3.426309620265761E-270 response_to_chemical_stimulus GO:0042221 12133 2369 34 8 5200 16 1 false 0.45505979934188 0.45505979934188 0.0 response_to_biotic_stimulus GO:0009607 12133 494 34 2 5200 16 1 false 0.45767984059198563 0.45767984059198563 0.0 positive_regulation_of_cAMP_metabolic_process GO:0030816 12133 71 34 1 155 1 4 false 0.4580645161290261 0.4580645161290261 5.885583975701031E-46 transmembrane_transport GO:0055085 12133 728 34 3 7606 26 2 false 0.45971323218509247 0.45971323218509247 0.0 recombinational_repair GO:0000725 12133 48 34 1 416 5 2 false 0.4599920167755236 0.4599920167755236 4.005015877906007E-64 vasoconstriction GO:0042310 12133 46 34 1 100 1 1 false 0.4600000000000129 0.4600000000000129 1.3610812764552173E-29 membrane_organization GO:0061024 12133 787 34 5 3745 21 1 false 0.46051231291835615 0.46051231291835615 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I GO:0042590 12133 73 34 1 158 1 2 false 0.4620253164557137 0.4620253164557137 6.794891168245598E-47 covalent_chromatin_modification GO:0016569 12133 312 34 2 458 2 1 false 0.46358919476766813 0.46358919476766813 7.826311589520491E-124 primary_cilium GO:0072372 12133 75 34 1 161 1 1 false 0.4658385093167774 0.4658385093167774 7.918281853304186E-48 contractile_fiber_part GO:0044449 12133 144 34 1 7199 31 3 false 0.46617861375886827 0.46617861375886827 8.364096489052254E-306 regulation_of_cell_differentiation GO:0045595 12133 872 34 3 6612 19 3 false 0.46691021746713274 0.46691021746713274 0.0 single-organism_process GO:0044699 12133 8052 34 27 10446 34 1 false 0.4672962761938145 0.4672962761938145 0.0 urogenital_system_development GO:0001655 12133 231 34 1 2686 7 1 false 0.4675260257773257 0.4675260257773257 0.0 spindle_organization GO:0007051 12133 78 34 1 1776 14 3 false 0.4680159597576485 0.4680159597576485 2.2015050227101385E-138 positive_regulation_of_cell_cycle_process GO:0090068 12133 156 34 1 3297 13 3 false 0.46810581158908615 0.46810581158908615 4.623981712175632E-272 regulation_of_small_GTPase_mediated_signal_transduction GO:0051056 12133 335 34 2 1759 8 2 false 0.4686046040516834 0.4686046040516834 0.0 protein_monoubiquitination GO:0006513 12133 37 34 1 548 9 1 false 0.4695128406543746 0.4695128406543746 2.2069453336747442E-58 histone_modification GO:0016570 12133 306 34 2 2375 12 2 false 0.47023823329049586 0.47023823329049586 0.0 mitotic_spindle_checkpoint GO:0071174 12133 38 34 1 140 2 2 false 0.4706063720451865 0.4706063720451865 3.73538767395573E-35 forebrain_development GO:0030900 12133 242 34 1 3152 8 3 false 0.4726088015418237 0.4726088015418237 0.0 cytoplasmic_vesicle_part GO:0044433 12133 366 34 2 7185 31 3 false 0.47360685935773056 0.47360685935773056 0.0 response_to_insulin_stimulus GO:0032868 12133 216 34 2 313 2 1 false 0.4755468173998091 0.4755468173998091 1.4650294580642456E-83 endocytic_vesicle_membrane GO:0030666 12133 97 34 1 352 2 2 false 0.4757672882672999 0.4757672882672999 2.1109282121886535E-89 Fc-gamma_receptor_signaling_pathway_involved_in_phagocytosis GO:0038096 12133 72 34 1 151 1 4 false 0.47682119205296153 0.47682119205296153 6.349846956956757E-45 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 34 6 3780 24 4 false 0.4769127340437227 0.4769127340437227 0.0 cytoskeleton_organization GO:0007010 12133 719 34 3 2031 7 1 false 0.47699154753933 0.47699154753933 0.0 regulation_of_mitotic_cell_cycle GO:0007346 12133 281 34 2 929 5 2 false 0.47710157490216076 0.47710157490216076 1.7613668775256747E-246 positive_regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030804 12133 75 34 1 157 1 4 false 0.4777070063694132 0.4777070063694132 1.0054402594300752E-46 regulation_of_response_to_stress GO:0080134 12133 674 34 3 3466 13 2 false 0.47797909406803774 0.47797909406803774 0.0 actin_cytoskeleton_organization GO:0030036 12133 373 34 2 768 3 2 false 0.4784934649255652 0.4784934649255652 3.0657297438498186E-230 cell_activation_involved_in_immune_response GO:0002263 12133 119 34 1 1341 7 3 false 0.4790063262438652 0.4790063262438652 8.435334491810511E-174 contractile_fiber GO:0043292 12133 159 34 1 6670 27 2 false 0.479368244572543 0.479368244572543 0.0 sequence-specific_DNA_binding GO:0043565 12133 1189 34 4 2091 6 1 false 0.4794078162387161 0.4794078162387161 0.0 monovalent_inorganic_cation_transmembrane_transporter_activity GO:0015077 12133 198 34 1 413 1 2 false 0.47941888619856315 0.47941888619856315 1.708187099767858E-123 positive_regulation_of_protein_catabolic_process GO:0045732 12133 76 34 1 1198 10 4 false 0.48209593977643805 0.48209593977643805 2.335035261625238E-122 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 34 2 129 3 1 false 0.4824236632484805 0.4824236632484805 2.169508265339551E-38 axon_guidance GO:0007411 12133 295 34 1 611 1 2 false 0.48281505728322394 0.48281505728322394 5.229199602535248E-183 DNA_catabolic_process GO:0006308 12133 66 34 1 2145 21 3 false 0.48285484554991465 0.48285484554991465 1.9973602853494904E-127 positive_regulation_of_immune_effector_process GO:0002699 12133 87 34 1 706 5 3 false 0.48291587851759876 0.48291587851759876 7.573271162497966E-114 protein_binding_transcription_factor_activity GO:0000988 12133 488 34 2 10311 34 3 false 0.48308077939885785 0.48308077939885785 0.0 negative_regulation_of_organelle_organization GO:0010639 12133 168 34 1 2125 8 3 false 0.48315219983754865 0.48315219983754865 2.2467097914760192E-254 muscle_system_process GO:0003012 12133 252 34 1 1272 3 1 false 0.484669614070218 0.484669614070218 3.711105192357829E-274 purine_nucleoside_catabolic_process GO:0006152 12133 939 34 5 1085 5 3 false 0.4847915589422494 0.4847915589422494 2.1746006434797338E-185 mitochondrial_membrane GO:0031966 12133 359 34 1 1810 3 3 false 0.48502252646771227 0.48502252646771227 0.0 negative_regulation_of_cell_cycle_phase_transition GO:1901988 12133 217 34 2 442 3 3 false 0.48639595698429194 0.48639595698429194 2.4953498472018727E-132 cell_cortex GO:0005938 12133 175 34 1 6402 24 2 false 0.4864423423007356 0.4864423423007356 0.0 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 34 6 3453 23 4 false 0.4871089452879019 0.4871089452879019 0.0 purine_NTP-dependent_helicase_activity GO:0070035 12133 98 34 2 140 2 1 false 0.4884892086330724 0.4884892086330724 9.838676628741767E-37 cell_junction_organization GO:0034330 12133 181 34 1 7663 28 2 false 0.4885430486193877 0.4885430486193877 0.0 ribonucleotide_catabolic_process GO:0009261 12133 946 34 5 1294 6 3 false 0.48931961266204416 0.48931961266204416 0.0 lyase_activity GO:0016829 12133 230 34 1 4901 14 1 false 0.4902532147232347 0.4902532147232347 0.0 regulation_of_cAMP_metabolic_process GO:0030814 12133 133 34 1 465 2 3 false 0.49067482387843386 0.49067482387843386 3.255746313776628E-120 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 34 3 129 3 1 false 0.4912676249771082 0.4912676249771082 2.104544859412626E-28 signal_transduction_involved_in_DNA_integrity_checkpoint GO:0072401 12133 64 34 1 130 1 2 false 0.4923076923076922 0.4923076923076922 1.0680656075518395E-38 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 34 5 2877 14 6 false 0.4931298037049149 0.4931298037049149 0.0 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 34 2 129 3 1 false 0.49414026735030403 0.49414026735030403 2.1037655906323275E-38 negative_regulation_of_translation GO:0017148 12133 61 34 1 1470 16 4 false 0.49423058008005627 0.49423058008005627 1.1152524521517982E-109 regulation_of_developmental_process GO:0050793 12133 1233 34 4 7209 21 2 false 0.49495185348809895 0.49495185348809895 0.0 regulation_of_MAPK_cascade GO:0043408 12133 429 34 3 701 4 2 false 0.49579958057426765 0.49579958057426765 1.5434745144062482E-202 glycosyl_compound_metabolic_process GO:1901657 12133 1093 34 5 7599 32 2 false 0.4962249333111279 0.4962249333111279 0.0 response_to_interferon-gamma GO:0034341 12133 97 34 1 900 6 2 false 0.49654569197003107 0.49654569197003107 5.665951698458868E-133 motile_cilium GO:0031514 12133 80 34 1 161 1 1 false 0.49689440993789236 0.49689440993789236 5.465858030116064E-48 neuron_development GO:0048666 12133 654 34 2 1313 3 2 false 0.49714177991598485 0.49714177991598485 0.0 regulation_of_response_to_DNA_damage_stimulus GO:2001020 12133 80 34 1 741 6 2 false 0.49739143861842805 0.49739143861842805 1.553661553762129E-109 monovalent_inorganic_cation_transport GO:0015672 12133 302 34 1 606 1 1 false 0.49834983498356933 0.49834983498356933 1.1660817479890875E-181 cation_channel_activity GO:0005261 12133 216 34 1 433 1 2 false 0.4988452655890016 0.4988452655890016 1.1777872542675005E-129 nucleotide_catabolic_process GO:0009166 12133 969 34 5 1318 6 2 false 0.4989127590945578 0.4989127590945578 0.0 metal_ion_transmembrane_transporter_activity GO:0046873 12133 263 34 1 527 1 2 false 0.49905123339657426 0.49905123339657426 6.55805140577772E-158 retinal_cone_cell_differentiation GO:0042670 12133 4 34 1 8 1 1 false 0.4999999999999997 0.4999999999999997 0.014285714285714268 histone_H3-K4_methylation GO:0051568 12133 33 34 1 66 1 1 false 0.5000000000000062 0.5000000000000062 1.3851512057218646E-19 regulation_of_catabolic_process GO:0009894 12133 554 34 3 5455 26 2 false 0.5005585789172773 0.5005585789172773 0.0 ATP_catabolic_process GO:0006200 12133 318 34 2 1012 5 4 false 0.5011075246236468 0.5011075246236468 1.0026310858617265E-272 regulation_of_cytokine_production GO:0001817 12133 323 34 1 1562 3 2 false 0.5011693621229976 0.5011693621229976 0.0 protein_maturation GO:0051604 12133 123 34 1 5551 31 2 false 0.5016901093880725 0.5016901093880725 1.3126924681575497E-255 cellular_response_to_nitrogen_compound GO:1901699 12133 347 34 2 1721 8 2 false 0.5018008203980469 0.5018008203980469 0.0 cysteine-type_peptidase_activity GO:0008234 12133 295 34 1 586 1 1 false 0.5034129692832179 0.5034129692832179 1.2148857586981575E-175 basal_transcription_machinery_binding GO:0001098 12133 464 34 2 6397 23 1 false 0.5051090552119829 0.5051090552119829 0.0 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 34 8 2560 13 2 false 0.5059796089935797 0.5059796089935797 0.0 peptidyl-lysine_modification GO:0018205 12133 185 34 1 623 2 1 false 0.5060566804127797 0.5060566804127797 7.634244791194444E-164 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 34 2 2935 14 1 false 0.5094272613313938 0.5094272613313938 0.0 intracellular_protein_kinase_cascade GO:0007243 12133 806 34 4 1813 8 1 false 0.5104121927002063 0.5104121927002063 0.0 cellular_response_to_interferon-gamma GO:0071346 12133 83 34 1 392 3 2 false 0.5112124448441729 0.5112124448441729 2.629901965674187E-87 polysome GO:0005844 12133 22 34 1 569 18 1 false 0.5136446402876447 0.5136446402876447 4.138788255326549E-40 cell_junction_assembly GO:0034329 12133 159 34 1 1406 6 2 false 0.5139349671223498 0.5139349671223498 9.423437086545545E-215 endocytic_vesicle GO:0030139 12133 152 34 1 712 3 1 false 0.5140113902016873 0.5140113902016873 1.2528026489004738E-159 protein_dephosphorylation GO:0006470 12133 146 34 1 2505 12 2 false 0.5143402601898295 0.5143402601898295 5.1980515318736674E-241 MAPK_cascade GO:0000165 12133 502 34 3 806 4 1 false 0.5148409174195878 0.5148409174195878 3.7900857366173457E-231 positive_regulation_of_cAMP_biosynthetic_process GO:0030819 12133 69 34 1 134 1 5 false 0.5149253731343213 0.5149253731343213 7.0817799397690005E-40 regulation_of_epidermal_growth_factor_receptor_signaling_pathway GO:0042058 12133 60 34 1 198 2 2 false 0.5153053376402926 0.5153053376402926 2.9049351003528108E-52 immune_response-activating_signal_transduction GO:0002757 12133 299 34 4 352 4 2 false 0.5190298812936133 0.5190298812936133 2.8561568566531905E-64 microtubule_cytoskeleton GO:0015630 12133 734 34 2 1430 3 1 false 0.5199393287721287 0.5199393287721287 0.0 GTPase_binding GO:0051020 12133 137 34 1 1005 5 1 false 0.5201736896141022 0.5201736896141022 4.2154504665352884E-173 cation_transmembrane_transporter_activity GO:0008324 12133 365 34 1 701 1 2 false 0.5206847360912653 0.5206847360912653 5.744660517109641E-210 negative_regulation_of_hydrolase_activity GO:0051346 12133 241 34 1 2738 8 3 false 0.5219742279480476 0.5219742279480476 0.0 regulation_of_adaptive_immune_response GO:0002819 12133 78 34 1 570 5 2 false 0.5222107125369458 0.5222107125369458 3.127506712292269E-98 cellular_component GO:0005575 12133 10701 34 33 11221 34 1 false 0.5281258389546926 0.5281258389546926 0.0 protein_domain_specific_binding GO:0019904 12133 486 34 2 6397 23 1 false 0.5307049742912373 0.5307049742912373 0.0 regulation_of_primary_metabolic_process GO:0080090 12133 3921 34 17 7507 32 2 false 0.5312173830453708 0.5312173830453708 0.0 ribonucleoside_catabolic_process GO:0042454 12133 946 34 5 1073 5 2 false 0.5320005406987649 0.5320005406987649 9.25790942536024E-169 cytoplasmic_vesicle GO:0031410 12133 764 34 3 8540 31 3 false 0.533191759346484 0.533191759346484 0.0 tight_junction_assembly GO:0070830 12133 31 34 1 58 1 2 false 0.5344827586206974 0.5344827586206974 3.809192954277456E-17 phosphorus-oxygen_lyase_activity GO:0016849 12133 123 34 1 230 1 1 false 0.5347826086956033 0.5347826086956033 1.920154677041111E-68 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 34 4 2780 8 2 false 0.5348599408438748 0.5348599408438748 0.0 cAMP_metabolic_process GO:0046058 12133 143 34 1 1194 6 2 false 0.5356498942520943 0.5356498942520943 2.6525041284959264E-189 carboxylic_acid_binding GO:0031406 12133 186 34 1 2280 9 1 false 0.5357351672105026 0.5357351672105026 4.771798836819993E-279 protein_ubiquitination_involved_in_ubiquitin-dependent_protein_catabolic_process GO:0042787 12133 55 34 1 676 9 2 false 0.5362994129503924 0.5362994129503924 2.737610529852072E-82 nucleotide_binding GO:0000166 12133 1997 34 12 2103 12 2 false 0.5367095506961441 0.5367095506961441 1.0169073992212018E-181 antigen_processing_and_presentation_of_peptide_antigen_via_MHC_class_I GO:0002474 12133 88 34 1 163 1 1 false 0.5398773006135101 0.5398773006135101 2.2957799692832176E-48 nucleoside_triphosphate_catabolic_process GO:0009143 12133 932 34 5 1054 5 2 false 0.5399275587687933 0.5399275587687933 2.3625686453162704E-163 B_cell_mediated_immunity GO:0019724 12133 92 34 1 170 1 2 false 0.541176470588214 0.541176470588214 1.940857539818752E-50 actin_cytoskeleton GO:0015629 12133 327 34 1 1430 3 1 false 0.5413853199027208 0.5413853199027208 0.0 U5_snRNP GO:0005682 12133 80 34 4 93 4 1 false 0.5416861461742352 0.5416861461742352 3.852654648545616E-16 system_development GO:0048731 12133 2686 34 7 3304 8 2 false 0.5417921700784895 0.5417921700784895 0.0 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 34 1 202 7 1 false 0.5419318356902139 0.5419318356902139 5.801734415928739E-29 negative_regulation_of_signal_transduction GO:0009968 12133 571 34 2 3588 11 5 false 0.5424086994682588 0.5424086994682588 0.0 negative_regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000134 12133 84 34 1 260 2 3 false 0.5426195426195495 0.5426195426195495 1.712440969539876E-70 purine_nucleotide_metabolic_process GO:0006163 12133 1208 34 6 1337 6 2 false 0.5433645969325496 0.5433645969325496 1.5771526523631757E-183 mitochondrion_organization GO:0007005 12133 215 34 1 2031 7 1 false 0.5436389164473167 0.5436389164473167 4.082912305313268E-297 regulation_of_blood_vessel_size GO:0050880 12133 100 34 1 308 2 3 false 0.5446507889503569 0.5446507889503569 9.949875270663928E-84 purine_ribonucleoside_catabolic_process GO:0046130 12133 939 34 5 1060 5 3 false 0.5448401233302466 0.5448401233302466 8.715047292960447E-163 membrane_invagination GO:0010324 12133 411 34 3 784 5 1 false 0.5454848740315219 0.5454848740315219 8.658368437912315E-235 regulation_of_cyclic_nucleotide_metabolic_process GO:0030799 12133 156 34 1 478 2 2 false 0.546669824478405 0.546669824478405 1.998151187516486E-130 small_conjugating_protein_ligase_binding GO:0044389 12133 147 34 1 1005 5 1 false 0.5472448977031441 0.5472448977031441 6.302468729220369E-181 regulation_of_endopeptidase_activity GO:0052548 12133 264 34 1 480 1 2 false 0.550000000000017 0.550000000000017 9.691263405564588E-143 cellular_response_to_organic_nitrogen GO:0071417 12133 323 34 2 1478 8 4 false 0.5502715242867118 0.5502715242867118 0.0 ATPase_activity,_coupled GO:0042623 12133 228 34 2 307 2 1 false 0.5509356837196387 0.5509356837196387 1.7947531856464704E-75 neurogenesis GO:0022008 12133 940 34 3 2425 7 2 false 0.5530467811987871 0.5530467811987871 0.0 regulation_of_cellular_response_to_stress GO:0080135 12133 270 34 1 6503 19 3 false 0.5537395140881811 0.5537395140881811 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 34 3 6358 18 2 false 0.5543131523003184 0.5543131523003184 0.0 G1_DNA_damage_checkpoint GO:0044783 12133 70 34 1 126 1 1 false 0.5555555555555676 0.5555555555555676 3.590272155218709E-37 protein_acylation GO:0043543 12133 155 34 1 2370 12 1 false 0.5567431620966979 0.5567431620966979 6.767829300235778E-248 single-stranded_RNA_binding GO:0003727 12133 40 34 1 763 15 1 false 0.5575581668487934 0.5575581668487934 1.1547828689277465E-67 intracellular_estrogen_receptor_signaling_pathway GO:0030520 12133 34 34 1 102 2 1 false 0.5577557755775552 0.5577557755775552 7.615480469304384E-28 synaptic_transmission GO:0007268 12133 515 34 1 923 1 2 false 0.5579631635971848 0.5579631635971848 2.6714189194289816E-274 positive_regulation_of_protein_insertion_into_mitochondrial_membrane_involved_in_apoptotic_signaling_pathway GO:1900740 12133 24 34 1 43 1 3 false 0.558139534883719 0.558139534883719 1.2492622608986976E-12 skeletal_muscle_organ_development GO:0060538 12133 172 34 1 308 1 1 false 0.5584415584415203 0.5584415584415203 3.4535917571053045E-91 passive_transmembrane_transporter_activity GO:0022803 12133 304 34 1 544 1 1 false 0.5588235294118147 0.5588235294118147 2.1953421087848878E-161 chromatin GO:0000785 12133 287 34 1 512 1 1 false 0.5605468749999285 0.5605468749999285 9.050120143931621E-152 nuclear_speck GO:0016607 12133 147 34 2 272 3 1 false 0.5607529604707322 0.5607529604707322 6.6218564870724965E-81 cyclic_purine_nucleotide_metabolic_process GO:0052652 12133 151 34 1 269 1 2 false 0.5613382899628113 0.5613382899628113 1.6379011785432358E-79 regulation_of_nucleotide_metabolic_process GO:0006140 12133 458 34 2 4239 17 3 false 0.5624803261359757 0.5624803261359757 0.0 cellular_cation_homeostasis GO:0030003 12133 289 34 1 513 1 2 false 0.5633528265106433 0.5633528265106433 6.525965777081911E-152 mRNA_3'-end_processing GO:0031124 12133 86 34 2 386 8 2 false 0.5635785945399873 0.5635785945399873 2.4694341980396157E-88 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 34 2 129 3 1 false 0.5642996932796249 0.5642996932796249 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 34 2 129 3 1 false 0.5642996932796249 0.5642996932796249 3.3394798770258706E-38 regulation_of_lymphocyte_activation GO:0051249 12133 245 34 1 434 1 2 false 0.5645161290321338 0.5645161290321338 2.1869753110099554E-128 mitochondrial_transport GO:0006839 12133 124 34 1 2454 16 2 false 0.5649224354670707 0.5649224354670707 1.607876790046367E-212 regulation_of_cysteine-type_endopeptidase_activity GO:2000116 12133 174 34 1 308 1 2 false 0.5649350649350205 0.5649350649350205 5.66231040699253E-91 histone_mRNA_metabolic_process GO:0008334 12133 27 34 1 573 17 1 false 0.565042810599213 0.565042810599213 6.871324608301151E-47 binding GO:0005488 12133 8962 34 30 10257 34 1 false 0.5681231680433905 0.5681231680433905 0.0 substrate-specific_channel_activity GO:0022838 12133 291 34 1 512 1 2 false 0.5683593749999285 0.5683593749999285 2.547694139879492E-151 macromolecule_modification GO:0043412 12133 2461 34 13 6052 32 1 false 0.5688908112727309 0.5688908112727309 0.0 regulation_of_cell_cycle_process GO:0010564 12133 382 34 2 1096 5 2 false 0.5691224846959375 0.5691224846959375 7.137372224746455E-307 negative_regulation_of_phosphate_metabolic_process GO:0045936 12133 278 34 1 2776 8 3 false 0.5705670657804298 0.5705670657804298 0.0 cell_projection_morphogenesis GO:0048858 12133 541 34 1 946 1 3 false 0.5718816067655231 0.5718816067655231 1.1683643564827775E-279 antigen_processing_and_presentation GO:0019882 12133 185 34 1 1618 7 1 false 0.5732790812462076 0.5732790812462076 5.091289488805967E-249 transition_metal_ion_binding GO:0046914 12133 1457 34 3 2699 5 1 false 0.5744198282388536 0.5744198282388536 0.0 ribonucleotide_metabolic_process GO:0009259 12133 1202 34 6 1318 6 2 false 0.5747195280802102 0.5747195280802102 7.680938106405399E-170 multicellular_organismal_development GO:0007275 12133 3069 34 8 4373 11 2 false 0.5748707154754236 0.5748707154754236 0.0 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 34 2 129 3 1 false 0.5759161554660286 0.5759161554660286 4.0186961232005657E-38 regulation_of_actin_cytoskeleton_organization GO:0032956 12133 166 34 1 476 2 3 false 0.576337903582687 0.576337903582687 5.437988564533384E-133 striated_muscle_cell_differentiation GO:0051146 12133 203 34 2 267 2 1 false 0.5773703922728246 0.5773703922728246 2.4098375851666058E-63 nuclear_export GO:0051168 12133 116 34 2 688 11 2 false 0.577942129582254 0.577942129582254 6.892155989004194E-135 cellular_response_to_stimulus GO:0051716 12133 4236 34 14 7871 26 2 false 0.5786180383840861 0.5786180383840861 0.0 nucleoside_triphosphate_metabolic_process GO:0009141 12133 1014 34 5 1319 6 1 false 0.5788190907221463 0.5788190907221463 6.536050345296563E-309 cyclic_nucleotide_metabolic_process GO:0009187 12133 177 34 1 1317 6 1 false 0.5801016658784943 0.5801016658784943 5.758082552903037E-225 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 34 7 307 10 1 false 0.5803343914753598 0.5803343914753598 1.4733469150792184E-83 spliceosomal_snRNP_assembly GO:0000387 12133 30 34 1 259 7 2 false 0.5821185930396944 0.5821185930396944 6.073894661120439E-40 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 34 3 1304 3 1 false 0.5821746997452448 0.5821746997452448 1.004636319027547E-252 single-organism_cellular_process GO:0044763 12133 7541 34 26 9888 34 2 false 0.5822233044278016 0.5822233044278016 0.0 skeletal_muscle_tissue_development GO:0007519 12133 168 34 1 288 1 2 false 0.5833333333332881 0.5833333333332881 2.348024843062379E-84 positive_regulation_of_catabolic_process GO:0009896 12133 137 34 1 3517 22 3 false 0.58388412286976 0.58388412286976 1.0965595914697655E-250 regulation_of_cell_activation GO:0050865 12133 303 34 1 6351 18 2 false 0.585686670600091 0.585686670600091 0.0 response_to_nitrogen_compound GO:1901698 12133 552 34 2 2369 8 1 false 0.5895254281892433 0.5895254281892433 0.0 endosomal_transport GO:0016197 12133 133 34 1 2454 16 2 false 0.5911282728427545 0.5911282728427545 7.966947585336105E-224 amino_acid_binding GO:0016597 12133 110 34 1 186 1 1 false 0.5913978494623976 0.5913978494623976 3.905422178213833E-54 cellular_component_organization GO:0016043 12133 3745 34 21 3839 21 1 false 0.5933479614571868 0.5933479614571868 4.153510440731863E-191 DNA_damage_response,_signal_transduction_by_p53_class_mediator GO:0030330 12133 105 34 2 136 2 2 false 0.5947712418300675 0.5947712418300675 2.4301849830786213E-31 cell_cycle_arrest GO:0007050 12133 202 34 1 998 4 2 false 0.5959214776427959 0.5959214776427959 1.5077994882682823E-217 muscle_tissue_development GO:0060537 12133 295 34 1 1132 3 1 false 0.5961400979081191 0.5961400979081191 3.412889797328503E-281 maintenance_of_protein_location GO:0045185 12133 100 34 1 1490 13 2 false 0.5962376938290407 0.5962376938290407 1.3409119998512189E-158 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 34 3 1350 7 4 false 0.5964763344958695 0.5964763344958695 0.0 regulation_of_nuclear_division GO:0051783 12133 100 34 1 712 6 2 false 0.5980933606616345 0.5980933606616345 7.811073934054147E-125 anatomical_structure_morphogenesis GO:0009653 12133 1664 34 4 3447 8 2 false 0.5984780431556624 0.5984780431556624 0.0 regulation_of_localization GO:0032879 12133 1242 34 4 7621 25 2 false 0.5996801367607272 0.5996801367607272 0.0 angiogenesis GO:0001525 12133 300 34 1 2776 8 3 false 0.5999468833272539 0.5999468833272539 0.0 somatic_cell_DNA_recombination GO:0016444 12133 50 34 1 190 3 1 false 0.6022147567500091 0.6022147567500091 4.229558413024195E-47 ion_channel_activity GO:0005216 12133 286 34 1 473 1 2 false 0.6046511627906472 0.6046511627906472 3.7303800171637374E-137 regulation_of_ion_transmembrane_transport GO:0034765 12133 176 34 1 662 3 3 false 0.6049791810449912 0.6049791810449912 9.171243521861199E-166 eye_photoreceptor_cell_development GO:0042462 12133 20 34 1 33 1 2 false 0.6060606060606016 0.6060606060606016 1.7446939147379062E-9 RNA_3'-end_processing GO:0031123 12133 98 34 2 601 12 1 false 0.6081418565959429 0.6081418565959429 1.9130441150898719E-115 estrogen_receptor_binding GO:0030331 12133 23 34 1 62 2 1 false 0.6081438392385131 0.6081438392385131 1.6756493074771417E-17 tissue_development GO:0009888 12133 1132 34 3 3099 8 1 false 0.60829428760181 0.60829428760181 0.0 double-stranded_DNA_binding GO:0003690 12133 109 34 1 179 1 1 false 0.6089385474860085 0.6089385474860085 1.5496409193142626E-51 purine_nucleotide_catabolic_process GO:0006195 12133 956 34 5 1223 6 3 false 0.6103320141827606 0.6103320141827606 6.80299167777575E-278 chromatin_organization GO:0006325 12133 539 34 2 689 2 1 false 0.6117350727373879 0.6117350727373879 4.375882251809235E-156 ATP_metabolic_process GO:0046034 12133 381 34 2 1209 6 3 false 0.6124243990735292 0.6124243990735292 0.0 signal_transduction_involved_in_DNA_damage_checkpoint GO:0072422 12133 64 34 1 170 2 3 false 0.6126000696135618 0.6126000696135618 2.004129732487635E-48 maintenance_of_location GO:0051235 12133 184 34 1 4158 21 2 false 0.6143512420998596 0.6143512420998596 0.0 protein_K63-linked_ubiquitination GO:0070534 12133 28 34 1 163 5 1 false 0.6153286578727273 0.6153286578727273 4.092462206953933E-32 immune_effector_process GO:0002252 12133 445 34 2 1618 7 1 false 0.6157029576980655 0.6157029576980655 0.0 T_cell_receptor_signaling_pathway GO:0050852 12133 88 34 2 112 2 1 false 0.6158301158301143 0.6158301158301143 5.828412725788921E-25 phagocytosis GO:0006909 12133 149 34 1 2417 15 2 false 0.6160705989574129 0.6160705989574129 3.130675140672653E-242 somatic_diversification_of_immunoglobulins GO:0016445 12133 45 34 1 73 1 2 false 0.6164383561643858 0.6164383561643858 8.158943815315171E-21 protein_ubiquitination GO:0016567 12133 548 34 9 578 9 1 false 0.6168486005575429 0.6168486005575429 7.913703273197485E-51 regulation_of_G1/S_transition_of_mitotic_cell_cycle GO:2000045 12133 103 34 1 269 2 2 false 0.6200688009764193 0.6200688009764193 3.613555574654199E-77 positive_regulation_of_cell_activation GO:0050867 12133 215 34 1 3002 13 3 false 0.620188044771507 0.620188044771507 0.0 cation_homeostasis GO:0055080 12133 330 34 1 532 1 1 false 0.6203007518797987 0.6203007518797987 1.1320770482912473E-152 vesicle GO:0031982 12133 834 34 3 7980 30 1 false 0.6203036768003587 0.6203036768003587 0.0 microtubule_organizing_center GO:0005815 12133 413 34 1 1076 2 2 false 0.620553298175615 0.620553298175615 2.6476518998275E-310 embryo_development_ending_in_birth_or_egg_hatching GO:0009792 12133 477 34 1 768 1 1 false 0.6210937499998362 0.6210937499998362 1.6461815804374103E-220 vascular_process_in_circulatory_system GO:0003018 12133 118 34 1 307 2 1 false 0.6217666219580926 0.6217666219580926 3.250495259622763E-88 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 34 2 129 3 1 false 0.6219528245742534 0.6219528245742534 1.1512773005265922E-37 purine_ribonucleotide_catabolic_process GO:0009154 12133 946 34 5 1202 6 3 false 0.6234256527068106 0.6234256527068106 1.616697592155103E-269 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 34 2 312 2 1 false 0.6262057877813638 0.6262057877813638 8.216510305576978E-69 in_utero_embryonic_development GO:0001701 12133 295 34 1 471 1 1 false 0.6263269639064891 0.6263269639064891 1.719393530200133E-134 cytoplasm GO:0005737 12133 6938 34 25 9083 33 1 false 0.6265472580630824 0.6265472580630824 0.0 acid-amino_acid_ligase_activity GO:0016881 12133 351 34 6 379 6 1 false 0.6289589919755253 0.6289589919755253 5.324332733169013E-43 histone_acetylation GO:0016573 12133 121 34 1 309 2 2 false 0.6306056403142446 0.6306056403142446 3.1224257129978892E-89 response_to_inorganic_substance GO:0010035 12133 277 34 1 2369 8 1 false 0.6307744409719129 0.6307744409719129 0.0 PML_body GO:0016605 12133 77 34 1 272 3 1 false 0.6331473241202477 0.6331473241202477 7.662735942565743E-70 negative_regulation_of_signaling GO:0023057 12133 597 34 2 4884 17 3 false 0.6334184537518519 0.6334184537518519 0.0 dephosphorylation GO:0016311 12133 328 34 1 2776 8 1 false 0.6347858846442663 0.6347858846442663 0.0 envelope GO:0031975 12133 641 34 2 9983 33 1 false 0.6351255075576719 0.6351255075576719 0.0 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 34 9 106 9 2 false 0.635933164816916 0.635933164816916 9.867686559172291E-9 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 34 6 4456 24 4 false 0.6364354884105811 0.6364354884105811 0.0 apical_junction_assembly GO:0043297 12133 37 34 1 58 1 1 false 0.6379310344827669 0.6379310344827669 2.991639077401756E-16 negative_regulation_of_cell_communication GO:0010648 12133 599 34 2 4860 17 3 false 0.6381776890117683 0.6381776890117683 0.0 heart_development GO:0007507 12133 343 34 1 2876 8 3 false 0.6384262853688699 0.6384262853688699 0.0 sensory_organ_development GO:0007423 12133 343 34 1 2873 8 2 false 0.6388361559668125 0.6388361559668125 0.0 cytokine_production GO:0001816 12133 362 34 1 4095 11 1 false 0.6391902525931674 0.6391902525931674 0.0 egress_of_virus_within_host_cell GO:0046788 12133 11 34 1 28 2 2 false 0.640211640211643 0.640211640211643 4.656755228837597E-8 cell_development GO:0048468 12133 1255 34 3 3306 8 4 false 0.6408147406212213 0.6408147406212213 0.0 peptidyl-lysine_acetylation GO:0018394 12133 127 34 1 198 1 2 false 0.6414141414141271 0.6414141414141271 1.293028032371008E-55 GTPase_activity GO:0003924 12133 612 34 3 1061 5 2 false 0.6420364666593191 0.6420364666593191 4.702100395E-313 organelle_organization GO:0006996 12133 2031 34 7 7663 28 2 false 0.6423856020985528 0.6423856020985528 0.0 intracellular_steroid_hormone_receptor_signaling_pathway GO:0030518 12133 102 34 2 217 4 1 false 0.6427939873263465 0.6427939873263465 1.2933579260360868E-64 cellular_response_to_hormone_stimulus GO:0032870 12133 384 34 2 1510 8 3 false 0.6441867931448424 0.6441867931448424 0.0 eye_development GO:0001654 12133 222 34 1 343 1 1 false 0.6472303206996914 0.6472303206996914 4.445039433028117E-96 blood_coagulation GO:0007596 12133 443 34 2 550 2 3 false 0.6484716012585028 0.6484716012585028 4.662213706291943E-117 regulation_of_Rho_GTPase_activity GO:0032319 12133 95 34 1 233 2 2 false 0.650251590942715 0.650251590942715 7.3761210037366725E-68 regulation_of_anatomical_structure_size GO:0090066 12133 256 34 1 2082 8 1 false 0.6505867011303024 0.6505867011303024 0.0 leukocyte_mediated_immunity GO:0002443 12133 182 34 1 445 2 1 false 0.6512501265310585 0.6512501265310585 4.746005199012963E-130 chromatin_binding GO:0003682 12133 309 34 1 8962 30 1 false 0.6515836941228086 0.6515836941228086 0.0 ATP_binding GO:0005524 12133 1212 34 6 1638 8 3 false 0.6534303688247163 0.6534303688247163 0.0 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 34 2 129 3 1 false 0.6558694607215028 0.6558694607215028 3.5310664374642874E-37 negative_regulation_of_multicellular_organismal_process GO:0051241 12133 306 34 1 5033 17 3 false 0.6563344325401332 0.6563344325401332 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 34 5 1180 15 1 false 0.6594802913055453 0.6594802913055453 0.0 negative_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051436 12133 66 34 2 81 2 2 false 0.6620370370370483 0.6620370370370483 1.2278945146862784E-16 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 34 6 4582 25 3 false 0.6655460091262155 0.6655460091262155 0.0 ribonucleoside_triphosphate_catabolic_process GO:0009203 12133 929 34 5 1007 5 2 false 0.6676794120268628 0.6676794120268628 1.4040993054667365E-118 regulation_of_GTPase_activity GO:0043087 12133 277 34 1 1145 4 3 false 0.6702923858528408 0.6702923858528408 2.6919247726004267E-274 organophosphate_metabolic_process GO:0019637 12133 1549 34 6 7521 32 2 false 0.6708759747073074 0.6708759747073074 0.0 mitotic_DNA_integrity_checkpoint GO:0044774 12133 78 34 1 183 2 2 false 0.6721311475409307 0.6721311475409307 1.0111677973178846E-53 toll-like_receptor_signaling_pathway GO:0002224 12133 129 34 3 147 3 1 false 0.6738530650805338 0.6738530650805338 1.843896992838607E-23 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 34 17 6638 32 2 false 0.6742448876854075 0.6742448876854075 0.0 microtubule_cytoskeleton_organization GO:0000226 12133 259 34 1 831 3 2 false 0.6744082844812636 0.6744082844812636 4.0880234187670296E-223 adenyl_ribonucleotide_binding GO:0032559 12133 1231 34 6 1645 8 2 false 0.6745548630715769 0.6745548630715769 0.0 purine_nucleoside_triphosphate_catabolic_process GO:0009146 12133 930 34 5 1006 5 2 false 0.674638232892963 0.674638232892963 2.1893990019353197E-116 adenyl_nucleotide_binding GO:0030554 12133 1235 34 6 1650 8 1 false 0.6749460680970498 0.6749460680970498 0.0 locomotion GO:0040011 12133 1045 34 3 10446 34 1 false 0.6751760368914084 0.6751760368914084 0.0 spliceosomal_complex_assembly GO:0000245 12133 38 34 1 259 7 2 false 0.6753013141227375 0.6753013141227375 1.791986159229858E-46 protein_complex_binding GO:0032403 12133 306 34 1 6397 23 1 false 0.6767662203765663 0.6767662203765663 0.0 endosomal_part GO:0044440 12133 257 34 1 7185 31 3 false 0.6774710933814923 0.6774710933814923 0.0 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 34 2 129 3 1 false 0.6781038271379052 0.6781038271379052 8.751505837166389E-37 programmed_cell_death GO:0012501 12133 1385 34 4 1525 4 1 false 0.6800591999761461 0.6800591999761461 2.142172117700311E-202 cell_part_morphogenesis GO:0032990 12133 551 34 1 810 1 1 false 0.6802469135803918 0.6802469135803918 1.1709501739830369E-219 immunoglobulin_production GO:0002377 12133 64 34 1 94 1 1 false 0.68085106382981 0.68085106382981 3.0952886871689963E-25 spindle GO:0005819 12133 221 34 1 4762 24 4 false 0.6812417077339736 0.6812417077339736 0.0 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 34 4 5183 18 2 false 0.6822361876162113 0.6822361876162113 0.0 response_to_metal_ion GO:0010038 12133 189 34 1 277 1 1 false 0.6823104693141068 0.6823104693141068 1.2236423246824455E-74 chemical_homeostasis GO:0048878 12133 677 34 1 990 1 1 false 0.6838383838382459 0.6838383838382459 1.9931274413677286E-267 purine_ribonucleoside_triphosphate_catabolic_process GO:0009207 12133 929 34 5 1002 5 3 false 0.6845391878397185 0.6845391878397185 5.68242981185093E-113 guanosine-containing_compound_metabolic_process GO:1901068 12133 634 34 3 1053 5 1 false 0.686498997974067 0.686498997974067 1.6418245301060377E-306 interaction_with_host GO:0051701 12133 387 34 5 417 5 2 false 0.6871651445785305 0.6871651445785305 1.9217516081652173E-46 regulation_of_locomotion GO:0040012 12133 398 34 1 6714 19 2 false 0.6873513419991434 0.6873513419991434 0.0 response_to_stimulus GO:0050896 12133 5200 34 16 10446 34 1 false 0.6873912381472149 0.6873912381472149 0.0 ribose_phosphate_biosynthetic_process GO:0046390 12133 279 34 1 1586 6 3 false 0.6874241817099958 0.6874241817099958 1.5665E-319 guanyl_nucleotide_binding GO:0019001 12133 450 34 2 1650 8 1 false 0.6875563359722685 0.6875563359722685 0.0 S-adenosylmethionine-dependent_methyltransferase_activity GO:0008757 12133 87 34 1 126 1 1 false 0.6904761904761948 0.6904761904761948 1.8124217932719872E-33 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 34 2 178 3 1 false 0.6905351361646463 0.6905351361646463 1.7238002808689451E-50 guanyl_ribonucleotide_binding GO:0032561 12133 450 34 2 1641 8 2 false 0.6909314039120336 0.6909314039120336 0.0 signal_transducer_activity GO:0004871 12133 1070 34 3 3547 11 2 false 0.6918802673784386 0.6918802673784386 0.0 purine-containing_compound_metabolic_process GO:0072521 12133 1232 34 6 5323 29 5 false 0.6931058803292155 0.6931058803292155 0.0 organelle_envelope GO:0031967 12133 629 34 2 7756 29 3 false 0.6942280197111612 0.6942280197111612 0.0 regulation_of_cellular_component_movement GO:0051270 12133 412 34 1 6475 18 3 false 0.6942533726343523 0.6942533726343523 0.0 taxis GO:0042330 12133 488 34 1 1496 3 2 false 0.6943920837433989 0.6943920837433989 0.0 negative_regulation_of_gene_expression GO:0010629 12133 817 34 5 3906 27 3 false 0.6949124630141987 0.6949124630141987 0.0 regulation_of_immune_effector_process GO:0002697 12133 188 34 1 891 5 2 false 0.6951546227820826 0.6951546227820826 1.2449327492079068E-198 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 34 9 181 9 1 false 0.695418000696852 0.695418000696852 8.905994863592909E-13 muscle_organ_development GO:0007517 12133 308 34 1 1966 7 2 false 0.6972088010460822 0.6972088010460822 0.0 cellular_component_movement GO:0006928 12133 1012 34 3 7541 26 1 false 0.6975132552388357 0.6975132552388357 0.0 cell_differentiation GO:0030154 12133 2154 34 7 2267 7 1 false 0.6987917792378382 0.6987917792378382 2.602261335719434E-194 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 34 2 129 3 1 false 0.6999834050540257 0.6999834050540257 2.4714073881998435E-36 GTP_metabolic_process GO:0046039 12133 625 34 3 1193 6 3 false 0.7003697346604754 0.7003697346604754 0.0 negative_regulation_of_response_to_stimulus GO:0048585 12133 687 34 2 5830 20 3 false 0.7014006175119554 0.7014006175119554 0.0 epithelial_cell_migration GO:0010631 12133 130 34 1 185 1 2 false 0.7027027027027377 0.7027027027027377 1.9916445787710798E-48 carbohydrate_derivative_metabolic_process GO:1901135 12133 1584 34 6 7451 32 1 false 0.7032207188422126 0.7032207188422126 0.0 molecular_transducer_activity GO:0060089 12133 1070 34 3 10257 34 1 false 0.7035957387818824 0.7035957387818824 0.0 G2/M_transition_of_mitotic_cell_cycle GO:0000086 12133 120 34 1 361 3 1 false 0.7037065615217533 0.7037065615217533 4.560830022372086E-99 negative_regulation_of_phosphorus_metabolic_process GO:0010563 12133 278 34 1 3568 15 3 false 0.7045508196953617 0.7045508196953617 0.0 maintenance_of_protein_location_in_cell GO:0032507 12133 90 34 1 933 12 3 false 0.7062062220204489 0.7062062220204489 6.448935914517526E-128 cellular_developmental_process GO:0048869 12133 2267 34 7 7817 27 2 false 0.7064091413331042 0.7064091413331042 0.0 somatic_diversification_of_immunoglobulins_involved_in_immune_response GO:0002208 12133 34 34 1 48 1 2 false 0.708333333333333 0.708333333333333 2.0733096446974964E-12 nucleoside_binding GO:0001882 12133 1639 34 8 4455 24 3 false 0.7087751768931418 0.7087751768931418 0.0 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 34 3 1779 4 1 false 0.7093826649910489 0.7093826649910489 0.0 cell_cycle_phase GO:0022403 12133 253 34 1 953 4 1 false 0.709578044568868 0.709578044568868 1.0384727319913012E-238 adenylate_cyclase_activity GO:0004016 12133 103 34 1 145 1 3 false 0.710344827586197 0.710344827586197 1.7288474062512548E-37 modification-dependent_protein_catabolic_process GO:0019941 12133 378 34 6 400 6 2 false 0.7106143107441765 0.7106143107441765 1.150456419433401E-36 proteasomal_protein_catabolic_process GO:0010498 12133 231 34 3 498 7 2 false 0.7114575535855512 0.7114575535855512 1.2543475178088858E-148 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 34 1 1631 9 2 false 0.7117036733419813 0.7117036733419813 3.3133814045702313E-271 regulation_of_ion_transport GO:0043269 12133 307 34 1 1393 5 2 false 0.7125845993317292 0.7125845993317292 3.368915E-318 brain_development GO:0007420 12133 420 34 1 2904 8 3 false 0.713891675304114 0.713891675304114 0.0 system_process GO:0003008 12133 1272 34 3 4095 11 1 false 0.7141731189843485 0.7141731189843485 0.0 cellular_chemical_homeostasis GO:0055082 12133 525 34 1 734 1 2 false 0.7152588555855657 0.7152588555855657 1.1478565010718528E-189 hemostasis GO:0007599 12133 447 34 2 527 2 1 false 0.7191939452097564 0.7191939452097564 7.174896528140087E-97 mitochondrial_envelope GO:0005740 12133 378 34 1 803 2 2 false 0.7201889423392217 0.7201889423392217 2.632819629334664E-240 signal_transduction_involved_in_mitotic_cell_cycle_checkpoint GO:0072413 12133 63 34 1 134 2 2 false 0.7211311861743613 0.7211311861743613 8.460684206886756E-40 chromatin_modification GO:0016568 12133 458 34 2 539 2 1 false 0.7217896283219056 0.7217896283219056 1.802023694196357E-98 nucleobase-containing_small_molecule_metabolic_process GO:0055086 12133 1351 34 6 5657 29 2 false 0.7248308537210253 0.7248308537210253 0.0 nuclear_hormone_receptor_binding GO:0035257 12133 104 34 2 122 2 1 false 0.7256469313101672 0.7256469313101672 6.677251530520905E-22 response_to_organic_nitrogen GO:0010243 12133 519 34 2 1787 8 3 false 0.7259146241072608 0.7259146241072608 0.0 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 34 3 10311 34 3 false 0.7262228408411648 0.7262228408411648 0.0 regulation_of_purine_nucleotide_metabolic_process GO:1900542 12133 454 34 2 1211 6 2 false 0.7262630714498959 0.7262630714498959 0.0 regulation_of_systemic_arterial_blood_pressure GO:0003073 12133 56 34 1 117 2 1 false 0.7303271441202416 0.7303271441202416 9.090542259133476E-35 nitrogen_compound_transport GO:0071705 12133 428 34 2 2783 16 1 false 0.7307031806282225 0.7307031806282225 0.0 zinc_ion_binding GO:0008270 12133 1314 34 3 1457 3 1 false 0.7333478216482373 0.7333478216482373 2.194714234876188E-202 cellular_macromolecular_complex_assembly GO:0034622 12133 517 34 2 973 4 1 false 0.7334155160694497 0.7334155160694497 3.312522477266262E-291 mRNA_processing GO:0006397 12133 374 34 8 763 18 2 false 0.7351504456660186 0.7351504456660186 8.270510506831645E-229 adaptive_immune_response GO:0002250 12133 174 34 1 1006 7 1 false 0.7365049995424 0.7365049995424 1.8321069442753992E-200 cellular_protein_complex_disassembly GO:0043624 12133 149 34 9 154 9 1 false 0.736970396384362 0.736970396384362 1.4793035521715585E-9 microtubule-based_process GO:0007017 12133 378 34 1 7541 26 1 false 0.7379849399607528 0.7379849399607528 0.0 translation_elongation_factor_activity GO:0003746 12133 22 34 1 180 10 2 false 0.7381010119968567 0.7381010119968567 1.0368938565383413E-28 somatic_recombination_of_immunoglobulin_gene_segments GO:0016447 12133 40 34 1 54 1 2 false 0.7407407407407403 0.7407407407407403 3.081310036937439E-13 Ras_protein_signal_transduction GO:0007265 12133 365 34 2 547 3 1 false 0.7419619945323741 0.7419619945323741 2.1494674666292624E-150 regulation_of_nucleoside_metabolic_process GO:0009118 12133 308 34 1 3785 16 2 false 0.7435529298954198 0.7435529298954198 0.0 transcription_factor_binding GO:0008134 12133 715 34 2 6397 23 1 false 0.7455634463121427 0.7455634463121427 0.0 neuron_projection_morphogenesis GO:0048812 12133 475 34 1 637 1 2 false 0.7456828885398858 0.7456828885398858 3.7535814082411355E-156 regulation_of_adenylate_cyclase_activity GO:0045761 12133 103 34 1 138 1 4 false 0.7463768115942113 0.7463768115942113 1.4792034822830027E-33 epithelial_cell_differentiation GO:0030855 12133 397 34 1 2228 7 2 false 0.7473480577619788 0.7473480577619788 0.0 chromosome_organization GO:0051276 12133 689 34 2 2031 7 1 false 0.7478318585599681 0.7478318585599681 0.0 purine_nucleoside_metabolic_process GO:0042278 12133 1054 34 5 1257 6 2 false 0.749387902352061 0.749387902352061 1.399683863089717E-240 regulation_of_translation GO:0006417 12133 210 34 1 3605 23 4 false 0.7496196169003726 0.7496196169003726 0.0 metal_ion_transport GO:0030001 12133 455 34 1 606 1 1 false 0.7508250825082763 0.7508250825082763 4.665536224038032E-147 transport GO:0006810 12133 2783 34 16 2833 16 1 false 0.751509343170124 0.751509343170124 1.147202604491021E-108 GTP_catabolic_process GO:0006184 12133 614 34 3 957 5 4 false 0.7520983726720949 0.7520983726720949 2.3934835856107606E-270 regulation_of_Ras_GTPase_activity GO:0032318 12133 179 34 1 357 2 2 false 0.7521008403362168 0.7521008403362168 8.083441090582102E-107 regulation_of_multicellular_organismal_development GO:2000026 12133 953 34 2 3481 9 3 false 0.7535288923708579 0.7535288923708579 0.0 small_conjugating_protein_ligase_activity GO:0019787 12133 335 34 6 351 6 1 false 0.7542757049377355 0.7542757049377355 5.577217121688537E-28 cellular_response_to_oxygen-containing_compound GO:1901701 12133 551 34 2 1804 8 2 false 0.7558932370981926 0.7558932370981926 0.0 protein_import GO:0017038 12133 225 34 1 2509 15 2 false 0.7567046186336418 0.7567046186336418 0.0 nuclear_envelope GO:0005635 12133 258 34 1 3962 21 3 false 0.7577423437266584 0.7577423437266584 0.0 guanosine-containing_compound_catabolic_process GO:1901069 12133 617 34 3 956 5 2 false 0.7581211068017877 0.7581211068017877 3.936677708897206E-269 nuclear_import GO:0051170 12133 203 34 1 2389 16 3 false 0.7596140305668675 0.7596140305668675 7.452348105569065E-301 regulatory_region_DNA_binding GO:0000975 12133 1169 34 3 2091 6 2 false 0.7598230053753168 0.7598230053753168 0.0 regulation_of_biosynthetic_process GO:0009889 12133 3012 34 13 5483 26 2 false 0.7600427046285888 0.7600427046285888 0.0 substrate-specific_transmembrane_transporter_activity GO:0022891 12133 502 34 1 660 1 2 false 0.7606060606062449 0.7606060606062449 4.8010140095396714E-157 membrane-bounded_vesicle GO:0031988 12133 762 34 3 834 3 1 false 0.7624631202790539 0.7624631202790539 6.820230733401612E-106 purine_nucleotide_biosynthetic_process GO:0006164 12133 269 34 1 1265 6 3 false 0.7625252483902081 0.7625252483902081 1.9379490968147627E-283 single-organism_developmental_process GO:0044767 12133 2776 34 8 8064 27 2 false 0.7632498418576539 0.7632498418576539 0.0 lymphocyte_mediated_immunity GO:0002449 12133 139 34 1 182 1 1 false 0.7637362637362488 0.7637362637362488 8.778235670388515E-43 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 34 1 5157 16 3 false 0.7669004197306615 0.7669004197306615 0.0 JNK_cascade GO:0007254 12133 159 34 1 207 1 1 false 0.7681159420289673 0.7681159420289673 3.1556682987155503E-48 mRNA_export_from_nucleus GO:0006406 12133 60 34 1 116 2 2 false 0.7691154422788684 0.7691154422788684 1.7435958103584361E-34 endothelial_cell_migration GO:0043542 12133 100 34 1 130 1 1 false 0.7692307692307458 0.7692307692307458 3.8279880512589226E-30 signaling GO:0023052 12133 3878 34 11 10446 34 1 false 0.7724672404446837 0.7724672404446837 0.0 purine_ribonucleotide_biosynthetic_process GO:0009152 12133 265 34 1 1206 6 3 false 0.7751321315136926 0.7751321315136926 5.7559641067065754E-275 ribonucleotide_biosynthetic_process GO:0009260 12133 275 34 1 1250 6 3 false 0.7755638769665476 0.7755638769665476 3.3374763917028038E-285 DNA_damage_checkpoint GO:0000077 12133 126 34 1 574 6 2 false 0.7756214538585651 0.7756214538585651 1.5833464450994651E-130 mitotic_G1_DNA_damage_checkpoint GO:0031571 12133 70 34 1 90 1 3 false 0.7777777777777884 0.7777777777777884 1.9615250672171495E-20 endomembrane_system GO:0012505 12133 1211 34 3 9983 33 1 false 0.7815505023138057 0.7815505023138057 0.0 death GO:0016265 12133 1528 34 4 8052 27 1 false 0.7818191240503645 0.7818191240503645 0.0 ion_homeostasis GO:0050801 12133 532 34 1 677 1 1 false 0.7858197932053073 0.7858197932053073 5.041033537922393E-152 regulation_of_hydrolase_activity GO:0051336 12133 821 34 2 3094 10 2 false 0.7892631989709247 0.7892631989709247 0.0 proteasomal_ubiquitin-dependent_protein_catabolic_process GO:0043161 12133 220 34 3 381 6 2 false 0.789924074960594 0.789924074960594 4.820433761728018E-112 nervous_system_development GO:0007399 12133 1371 34 3 2686 7 1 false 0.7904924726300224 0.7904924726300224 0.0 Fc_receptor_signaling_pathway GO:0038093 12133 76 34 1 188 3 1 false 0.7908676167790357 0.7908676167790357 1.381050418692459E-54 regulation_of_mRNA_stability GO:0043488 12133 33 34 2 37 2 1 false 0.792792792792794 0.792792792792794 1.5141191611779804E-5 cellular_component_biogenesis GO:0044085 12133 1525 34 7 3839 21 1 false 0.7931361477960709 0.7931361477960709 0.0 DNA_damage_response,_signal_transduction_by_p53_class_mediator_resulting_in_cell_cycle_arrest GO:0006977 12133 63 34 1 116 2 3 false 0.7934032983508316 0.7934032983508316 2.4978330889301296E-34 catalytic_activity GO:0003824 12133 4901 34 14 10478 34 2 false 0.7954404956606799 0.7954404956606799 0.0 stress-activated_MAPK_cascade GO:0051403 12133 207 34 1 504 3 2 false 0.7962170064416874 0.7962170064416874 1.7060805667457382E-147 positive_regulation_of_leukocyte_activation GO:0002696 12133 206 34 1 756 5 4 false 0.7972118133780473 0.7972118133780473 1.5163059036704027E-191 transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway GO:0007169 12133 586 34 4 803 6 1 false 0.7979957534984075 0.7979957534984075 1.0286714317927864E-202 multicellular_organismal_signaling GO:0035637 12133 604 34 1 5594 14 2 false 0.7984250486878295 0.7984250486878295 0.0 spindle_assembly_checkpoint GO:0071173 12133 36 34 1 45 1 1 false 0.8000000000000007 0.8000000000000007 1.1284603934692157E-9 regulation_of_cAMP_biosynthetic_process GO:0030817 12133 124 34 1 155 1 4 false 0.8000000000000121 0.8000000000000121 2.5860077232155615E-33 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 34 14 6094 30 2 false 0.8007254062492725 0.8007254062492725 0.0 rRNA_metabolic_process GO:0016072 12133 107 34 1 258 3 1 false 0.8011792626232835 0.8011792626232835 1.860360860420455E-75 cell_death GO:0008219 12133 1525 34 4 7542 26 2 false 0.8012917030081805 0.8012917030081805 0.0 endopeptidase_activity GO:0004175 12133 470 34 1 586 1 1 false 0.802047781569667 0.802047781569667 5.73935751356398E-126 purine-containing_compound_biosynthetic_process GO:0072522 12133 280 34 1 4251 24 6 false 0.8059940943601926 0.8059940943601926 0.0 regulation_of_nucleotide_catabolic_process GO:0030811 12133 306 34 1 1279 6 3 false 0.8068713872237524 0.8068713872237524 9.116385096369177E-305 peptidase_activity GO:0008233 12133 614 34 1 2556 6 1 false 0.807990329185105 0.807990329185105 0.0 transferase_activity GO:0016740 12133 1779 34 4 4901 14 1 false 0.8085623288019707 0.8085623288019707 0.0 cell_morphogenesis_involved_in_differentiation GO:0000904 12133 584 34 1 1379 3 2 false 0.8087006940413087 0.8087006940413087 0.0 ion_binding GO:0043167 12133 4448 34 13 8962 30 1 false 0.8087305918770509 0.8087305918770509 0.0 isotype_switching GO:0045190 12133 34 34 1 42 1 2 false 0.8095238095238179 0.8095238095238179 8.472408985887957E-9 neuron_differentiation GO:0030182 12133 812 34 2 2154 7 2 false 0.8096689062625557 0.8096689062625557 0.0 localization_of_cell GO:0051674 12133 785 34 3 3467 18 1 false 0.8100145000402366 0.8100145000402366 0.0 cell_projection_part GO:0044463 12133 491 34 1 9983 33 2 false 0.8112013433846221 0.8112013433846221 0.0 central_nervous_system_development GO:0007417 12133 571 34 1 2686 7 2 false 0.8127110435264265 0.8127110435264265 0.0 Fc_receptor_mediated_stimulatory_signaling_pathway GO:0002431 12133 76 34 1 178 3 1 false 0.8142128772009969 0.8142128772009969 2.9073989409378337E-52 nucleotide_biosynthetic_process GO:0009165 12133 322 34 1 1318 6 2 false 0.8144502130323884 0.8144502130323884 2.1862113E-317 protein_localization_to_mitochondrion GO:0070585 12133 67 34 1 516 12 1 false 0.815185598883137 0.815185598883137 5.765661430685337E-86 translation_factor_activity,_nucleic_acid_binding GO:0008135 12133 82 34 1 971 19 2 false 0.815999792025822 0.815999792025822 1.7939571902377886E-121 transmission_of_nerve_impulse GO:0019226 12133 586 34 1 4105 11 3 false 0.8166856803193866 0.8166856803193866 0.0 nucleolus GO:0005730 12133 1357 34 7 4208 27 3 false 0.8178107311324315 0.8178107311324315 0.0 negative_regulation_of_cell_differentiation GO:0045596 12133 381 34 1 3552 15 4 false 0.8183220192699293 0.8183220192699293 0.0 negative_regulation_of_developmental_process GO:0051093 12133 463 34 1 4566 16 3 false 0.8197983806439543 0.8197983806439543 0.0 regulation_of_GTP_catabolic_process GO:0033124 12133 279 34 1 642 3 3 false 0.8198852142168194 0.8198852142168194 4.2701237450964594E-190 response_to_hormone_stimulus GO:0009725 12133 611 34 2 1784 8 2 false 0.8201103983795826 0.8201103983795826 0.0 mitochondrion GO:0005739 12133 1138 34 3 8213 31 2 false 0.8236580061639157 0.8236580061639157 0.0 regulation_of_leukocyte_activation GO:0002694 12133 278 34 1 948 5 3 false 0.8244405585363674 0.8244405585363674 2.7935655578419027E-248 histone_lysine_methylation GO:0034968 12133 66 34 1 80 1 1 false 0.8249999999999986 0.8249999999999986 6.630630379305838E-16 positive_regulation_of_mitochondrial_membrane_permeability GO:0035794 12133 38 34 1 46 1 1 false 0.8260869565217287 0.8260869565217287 3.832404138206993E-9 nucleic_acid_phosphodiester_bond_hydrolysis GO:0090305 12133 238 34 1 3799 27 1 false 0.8267482617763717 0.8267482617763717 0.0 antigen_processing_and_presentation_of_exogenous_antigen GO:0019884 12133 153 34 1 185 1 1 false 0.8270270270271043 0.8270270270271043 1.2806047113744547E-36 generation_of_neurons GO:0048699 12133 883 34 3 940 3 1 false 0.8287220853101755 0.8287220853101755 7.799501535546468E-93 double-strand_break_repair GO:0006302 12133 109 34 1 368 5 1 false 0.8292960688205664 0.8292960688205664 1.714085470943145E-96 endosome GO:0005768 12133 455 34 1 8213 31 2 false 0.829689770425123 0.829689770425123 0.0 regulation_of_cell_motility GO:2000145 12133 370 34 1 831 3 3 false 0.8297693349243264 0.8297693349243264 3.695619588048616E-247 substrate-specific_transporter_activity GO:0022892 12133 620 34 1 746 1 1 false 0.8310991957102674 0.8310991957102674 1.886990037563331E-146 cellular_ion_homeostasis GO:0006873 12133 478 34 1 575 1 2 false 0.8313043478262244 0.8313043478262244 1.064446434652655E-112 cellular_component_assembly GO:0022607 12133 1392 34 6 3836 21 2 false 0.8322806522533074 0.8322806522533074 0.0 hydrolase_activity GO:0016787 12133 2556 34 6 4901 14 1 false 0.8326152607837634 0.8326152607837634 0.0 single_organism_signaling GO:0044700 12133 3878 34 11 8052 27 2 false 0.8328361649633846 0.8328361649633846 0.0 interphase_of_mitotic_cell_cycle GO:0051329 12133 227 34 1 630 4 2 false 0.833460566240513 0.833460566240513 4.4826406352842784E-178 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 34 6 7461 32 2 false 0.8375814342521792 0.8375814342521792 0.0 cell-cell_junction_organization GO:0045216 12133 152 34 1 181 1 1 false 0.8397790055249296 0.8397790055249296 3.1886200066761254E-34 nonmotile_primary_cilium GO:0031513 12133 63 34 1 75 1 1 false 0.840000000000001 0.840000000000001 3.827913922822431E-14 response_to_decreased_oxygen_levels GO:0036293 12133 202 34 3 214 3 1 false 0.8403267426814965 0.8403267426814965 7.108512362452622E-20 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 34 7 207 7 1 false 0.8405294364978887 0.8405294364978887 3.3148479610294504E-10 cellular_metal_ion_homeostasis GO:0006875 12133 259 34 1 308 1 2 false 0.8409090909089498 0.8409090909089498 3.9623191237847456E-58 cell_proliferation GO:0008283 12133 1316 34 3 8052 27 1 false 0.8414855729613295 0.8414855729613295 0.0 metal_ion_homeostasis GO:0055065 12133 278 34 1 330 1 1 false 0.8424242424241729 0.8424242424241729 6.131976736615521E-62 chemotaxis GO:0006935 12133 488 34 1 2369 8 2 false 0.8425092725786505 0.8425092725786505 0.0 nucleic_acid_transport GO:0050657 12133 124 34 2 135 2 1 false 0.8431177446102683 0.8431177446102683 2.2345648964967124E-16 cell_morphogenesis_involved_in_neuron_differentiation GO:0048667 12133 465 34 1 766 2 2 false 0.8459018071985545 0.8459018071985545 4.217322594612318E-222 camera-type_eye_development GO:0043010 12133 188 34 1 222 1 1 false 0.846846846846853 0.846846846846853 7.102712609008063E-41 cell_projection GO:0042995 12133 976 34 2 9983 33 1 false 0.8469903484822872 0.8469903484822872 0.0 large_ribosomal_subunit GO:0015934 12133 73 34 4 132 9 1 false 0.8473283073248319 0.8473283073248319 5.5437540818743186E-39 lymphocyte_activation GO:0046649 12133 403 34 1 475 1 1 false 0.8484210526316471 0.8484210526316471 3.3805466364584557E-87 androgen_receptor_signaling_pathway GO:0030521 12133 62 34 1 102 2 1 false 0.8485730926033468 0.8485730926033468 2.6706454874295595E-29 nucleoplasm_part GO:0044451 12133 805 34 4 2767 19 2 false 0.8487416744613181 0.8487416744613181 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 34 13 4972 25 3 false 0.8492016023688108 0.8492016023688108 0.0 somatic_recombination_of_immunoglobulin_genes_involved_in_immune_response GO:0002204 12133 34 34 1 40 1 2 false 0.8500000000000089 0.8500000000000089 2.6052657631605196E-7 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 34 3 6622 19 1 false 0.8506217786074466 0.8506217786074466 0.0 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 34 1 147 2 1 false 0.8512720156555378 0.8512720156555378 3.485982605742994E-42 response_to_oxygen-containing_compound GO:1901700 12133 864 34 2 2369 8 1 false 0.8520548133151985 0.8520548133151985 0.0 positive_regulation_of_gene_expression GO:0010628 12133 1008 34 5 4103 28 3 false 0.8540262068435331 0.8540262068435331 0.0 androgen_receptor_binding GO:0050681 12133 38 34 1 62 2 1 false 0.8540454785827765 0.8540454785827765 1.0311688046013243E-17 regulation_of_cyclic_nucleotide_biosynthetic_process GO:0030802 12133 143 34 1 167 1 3 false 0.856287425149713 0.856287425149713 1.5904574919997758E-29 nucleoside_phosphate_biosynthetic_process GO:1901293 12133 323 34 1 4156 24 3 false 0.8573477200083808 0.8573477200083808 0.0 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 34 5 3972 25 4 false 0.8577964636601186 0.8577964636601186 0.0 ubiquitin_binding GO:0043130 12133 61 34 1 71 1 1 false 0.8591549295774618 0.8591549295774618 2.1657301017057942E-12 immune_system_development GO:0002520 12133 521 34 1 3460 12 2 false 0.8593920941711171 0.8593920941711171 0.0 biological_regulation GO:0065007 12133 6908 34 20 10446 34 1 false 0.860153911475462 0.860153911475462 0.0 regulation_of_biological_process GO:0050789 12133 6622 34 19 10446 34 2 false 0.8614462630915365 0.8614462630915365 0.0 regulation_of_purine_nucleotide_catabolic_process GO:0033121 12133 305 34 1 1088 6 3 false 0.8618167303416443 0.8618167303416443 1.7563474810306042E-279 nuclear_division GO:0000280 12133 326 34 2 351 2 1 false 0.8624338624341342 0.8624338624341342 8.671827254018066E-39 peptidyl-amino_acid_modification GO:0018193 12133 623 34 2 2370 12 1 false 0.8647898018828117 0.8647898018828117 0.0 inorganic_cation_transmembrane_transporter_activity GO:0022890 12133 316 34 1 365 1 1 false 0.8657534246575868 0.8657534246575868 4.982755146780477E-62 cell_cycle_checkpoint GO:0000075 12133 202 34 2 217 2 1 false 0.8662314388120638 0.8662314388120638 1.925703524045096E-23 methyltransferase_activity GO:0008168 12133 126 34 1 199 2 2 false 0.8666057560529297 0.8666057560529297 2.689097193899432E-56 organ_morphogenesis GO:0009887 12133 649 34 1 2908 8 3 false 0.8677575479629414 0.8677575479629414 0.0 centrosome GO:0005813 12133 327 34 1 3226 19 2 false 0.8695374101396731 0.8695374101396731 0.0 phosphorylation GO:0016310 12133 1421 34 3 2776 8 1 false 0.8708662287738209 0.8708662287738209 0.0 axonogenesis GO:0007409 12133 421 34 1 483 1 2 false 0.8716356107660534 0.8716356107660534 7.423880338325494E-80 multicellular_organismal_process GO:0032501 12133 4223 34 11 10446 34 1 false 0.8728908295623513 0.8728908295623513 0.0 muscle_contraction GO:0006936 12133 220 34 1 252 1 1 false 0.8730158730158051 0.8730158730158051 2.9388717314840356E-41 DNA_integrity_checkpoint GO:0031570 12133 130 34 1 202 2 1 false 0.8740948721737103 0.8740948721737103 1.23666756413938E-56 embryo_development GO:0009790 12133 768 34 1 3347 8 3 false 0.8760400893996257 0.8760400893996257 0.0 positive_regulation_of_transport GO:0051050 12133 413 34 1 4769 23 3 false 0.8761200681254304 0.8761200681254304 0.0 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 34 5 3847 28 4 false 0.8766519840740243 0.8766519840740243 0.0 cellular_homeostasis GO:0019725 12133 585 34 1 7566 26 2 false 0.8770391468403749 0.8770391468403749 0.0 purine_ribonucleotide_metabolic_process GO:0009150 12133 1192 34 6 1218 6 2 false 0.8783281168061138 0.8783281168061138 3.12960829510125E-54 antigen_processing_and_presentation_of_peptide_antigen GO:0048002 12133 163 34 1 185 1 1 false 0.881081081081119 0.881081081081119 5.464989090238489E-29 regulation_of_cytoskeleton_organization GO:0051493 12133 250 34 1 955 7 2 false 0.8814516490820095 0.8814516490820095 1.2229840665192896E-237 extracellular_region GO:0005576 12133 1152 34 2 10701 33 1 false 0.8842526937577523 0.8842526937577523 0.0 protein_methylation GO:0006479 12133 98 34 1 149 2 2 false 0.8843642300017935 0.8843642300017935 3.8389402861551994E-41 signal_transduction_involved_in_mitotic_G1_DNA_damage_checkpoint GO:0072431 12133 63 34 1 71 1 3 false 0.8873239436619828 0.8873239436619828 9.399268641403064E-11 negative_regulation_of_cell_proliferation GO:0008285 12133 455 34 1 2949 13 3 false 0.8873374285750432 0.8873374285750432 0.0 protein_kinase_binding GO:0019901 12133 341 34 1 384 1 1 false 0.8880208333333595 0.8880208333333595 5.20098898434574E-58 regulation_of_cellular_localization GO:0060341 12133 603 34 1 6869 24 3 false 0.8901900584012759 0.8901900584012759 0.0 cell_communication GO:0007154 12133 3962 34 11 7541 26 1 false 0.8931587795753151 0.8931587795753151 0.0 single-multicellular_organism_process GO:0044707 12133 4095 34 11 8057 27 2 false 0.8932649894700078 0.8932649894700078 0.0 transcription_cofactor_activity GO:0003712 12133 456 34 2 482 2 2 false 0.8949198160815699 0.8949198160815699 1.3948726648763881E-43 leukocyte_activation GO:0045321 12133 475 34 1 1729 7 2 false 0.8949215194792628 0.8949215194792628 0.0 G1/S_transition_of_mitotic_cell_cycle GO:0000082 12133 201 34 1 381 3 2 false 0.8954803958769892 0.8954803958769892 8.855041133991382E-114 adaptive_immune_response_based_on_somatic_recombination_of_immune_receptors_built_from_immunoglobulin_superfamily_domains GO:0002460 12133 156 34 1 174 1 1 false 0.8965517241379637 0.8965517241379637 7.444259624063543E-25 metal_ion_binding GO:0046872 12133 2699 34 5 2758 5 1 false 0.8974466762025094 0.8974466762025094 2.6200760259069314E-123 nuclear_transport GO:0051169 12133 331 34 2 1148 12 1 false 0.9022592822857431 0.9022592822857431 1.3196682196913852E-298 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 34 14 5532 30 4 false 0.9029488684691127 0.9029488684691127 0.0 protein_acetylation GO:0006473 12133 140 34 1 155 1 1 false 0.9032258064516349 0.9032258064516349 3.675799410957308E-21 nucleoside-triphosphatase_activity GO:0017111 12133 1059 34 5 1080 5 1 false 0.9063189430130167 0.9063189430130167 1.2343281293318376E-44 regulation_of_protein_phosphorylation GO:0001932 12133 787 34 3 1444 8 3 false 0.907393268836388 0.907393268836388 0.0 modification-dependent_macromolecule_catabolic_process GO:0043632 12133 381 34 6 672 14 1 false 0.9074462369680752 0.9074462369680752 6.935915883902889E-199 ubiquitin-dependent_protein_catabolic_process GO:0006511 12133 372 34 6 378 6 1 false 0.9078751437642244 0.9078751437642244 2.5686196448553377E-13 kinase_binding GO:0019900 12133 384 34 1 1005 5 1 false 0.9104748471401684 0.9104748471401684 2.0091697589355545E-289 epithelium_development GO:0060429 12133 627 34 1 1132 3 1 false 0.9115083232271376 0.9115083232271376 0.0 purine_ribonucleotide_binding GO:0032555 12133 1641 34 8 1660 8 2 false 0.9118404836621758 0.9118404836621758 8.870449707822982E-45 regulation_of_intracellular_transport GO:0032386 12133 276 34 1 1731 14 3 false 0.9129903787561976 0.9129903787561976 0.0 internal_protein_amino_acid_acetylation GO:0006475 12133 128 34 1 140 1 1 false 0.914285714285699 0.914285714285699 1.3721041217101573E-17 purine_ribonucleoside_metabolic_process GO:0046128 12133 1053 34 5 1072 5 2 false 0.9143124268728643 0.9143124268728643 3.811291228230986E-41 neuron_projection_development GO:0031175 12133 575 34 1 812 2 2 false 0.9150656308276155 0.9150656308276155 3.771933680434825E-212 antigen_processing_and_presentation_of_exogenous_peptide_antigen GO:0002478 12133 151 34 1 165 1 2 false 0.9151515151515951 0.9151515151515951 1.3866478491946915E-20 regulation_of_cellular_process GO:0050794 12133 6304 34 18 9757 33 2 false 0.9163906335057992 0.9163906335057992 0.0 developmental_process GO:0032502 12133 3447 34 8 10446 34 1 false 0.9164726567010515 0.9164726567010515 0.0 regulation_of_transport GO:0051049 12133 942 34 3 3017 16 2 false 0.9178567275347196 0.9178567275347196 0.0 mitochondrial_part GO:0044429 12133 557 34 1 7185 31 3 false 0.9184810571176474 0.9184810571176474 0.0 protein_processing GO:0016485 12133 113 34 1 123 1 1 false 0.918699186991829 0.918699186991829 6.665856545071852E-15 small_GTPase_binding GO:0031267 12133 126 34 1 137 1 1 false 0.9197080291970834 0.9197080291970834 1.8889221296599312E-16 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 34 8 2805 8 1 false 0.9201262054482057 0.9201262054482057 1.0460685646312495E-69 positive_regulation_of_cell_proliferation GO:0008284 12133 558 34 1 3155 13 3 false 0.9207809045768569 0.9207809045768569 0.0 interphase GO:0051325 12133 233 34 1 253 1 1 false 0.9209486166006322 0.9209486166006322 4.555981744751407E-30 transporter_activity GO:0005215 12133 746 34 1 10383 34 2 false 0.921072988390955 0.921072988390955 0.0 organophosphate_biosynthetic_process GO:0090407 12133 477 34 1 4948 25 2 false 0.9211947008979828 0.9211947008979828 0.0 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 34 2 78 2 1 false 0.9240759240759076 0.9240759240759076 1.3144749986854762E-5 organelle_membrane GO:0031090 12133 1619 34 3 9319 31 3 false 0.9246366774064247 0.9246366774064247 0.0 somatic_diversification_of_immune_receptors_via_germline_recombination_within_a_single_locus GO:0002562 12133 50 34 1 54 1 2 false 0.9259259259259376 0.9259259259259376 3.162045337406044E-6 regulation_of_cellular_catabolic_process GO:0031329 12133 494 34 1 5000 25 3 false 0.9262668224311006 0.9262668224311006 0.0 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 34 3 2528 11 3 false 0.926273357058971 0.926273357058971 0.0 vesicle-mediated_transport GO:0016192 12133 895 34 3 2783 16 1 false 0.9290080569462094 0.9290080569462094 0.0 protein_complex_biogenesis GO:0070271 12133 746 34 2 1525 7 1 false 0.930540491957942 0.930540491957942 0.0 regulation_of_protein_localization GO:0032880 12133 349 34 1 2148 15 2 false 0.9306870471642845 0.9306870471642845 0.0 cell-cell_signaling GO:0007267 12133 859 34 1 3969 11 2 false 0.9318906731074718 0.9318906731074718 0.0 ribosome_biogenesis GO:0042254 12133 144 34 1 243 3 1 false 0.9335959875378996 0.9335959875378996 8.984879194471426E-71 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 34 11 3120 16 4 false 0.9342019996921654 0.9342019996921654 0.0 chromosomal_part GO:0044427 12133 512 34 1 5337 27 2 false 0.9347828782840473 0.9347828782840473 0.0 transmembrane_transporter_activity GO:0022857 12133 544 34 1 904 3 2 false 0.9371627373734877 0.9371627373734877 4.222056161945909E-263 carbohydrate_derivative_biosynthetic_process GO:1901137 12133 525 34 1 4947 25 2 false 0.9399126726012621 0.9399126726012621 0.0 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 34 13 4544 29 3 false 0.9411283735016595 0.9411283735016595 0.0 identical_protein_binding GO:0042802 12133 743 34 1 6397 23 1 false 0.9418613936525218 0.9418613936525218 0.0 organonitrogen_compound_biosynthetic_process GO:1901566 12133 548 34 1 5099 25 2 false 0.9421293534092126 0.9421293534092126 0.0 response_to_radiation GO:0009314 12133 293 34 1 676 5 1 false 0.9422814760086866 0.9422814760086866 4.1946042901139895E-200 cell_projection_organization GO:0030030 12133 744 34 1 7663 28 2 false 0.9430181272946092 0.9430181272946092 0.0 response_to_wounding GO:0009611 12133 905 34 2 2540 11 1 false 0.9446451129585601 0.9446451129585601 0.0 cell_morphogenesis GO:0000902 12133 766 34 1 810 1 1 false 0.9456790123456539 0.9456790123456539 9.285456073507826E-74 ribonucleoside_metabolic_process GO:0009119 12133 1071 34 5 1083 5 1 false 0.9457144270360025 0.9457144270360025 1.9559437642804265E-28 ion_transport GO:0006811 12133 833 34 3 2323 15 1 false 0.9465520848845681 0.9465520848845681 0.0 internal_peptidyl-lysine_acetylation GO:0018393 12133 124 34 1 131 1 2 false 0.9465648854961779 0.9465648854961779 8.960493506706349E-12 Fc-gamma_receptor_signaling_pathway GO:0038094 12133 72 34 1 76 1 1 false 0.9473684210526206 0.9473684210526206 7.79438414622254E-7 protein_dimerization_activity GO:0046983 12133 779 34 1 6397 23 1 false 0.9498193639102827 0.9498193639102827 0.0 purine_nucleoside_triphosphate_metabolic_process GO:0009144 12133 1004 34 5 1014 5 1 false 0.9515596164819137 0.9515596164819137 3.301546202575714E-24 ribonucleoside_triphosphate_metabolic_process GO:0009199 12133 1004 34 5 1014 5 1 false 0.9515596164819137 0.9515596164819137 3.301546202575714E-24 Ras_GTPase_binding GO:0017016 12133 120 34 1 126 1 1 false 0.9523809523809658 0.9523809523809658 2.030392220357244E-10 peptidase_activity,_acting_on_L-amino_acid_peptides GO:0070011 12133 586 34 1 614 1 1 false 0.9543973941371671 0.9543973941371671 4.862693095923331E-49 intrinsic_to_membrane GO:0031224 12133 2375 34 1 2995 2 1 false 0.9572009907374975 0.9572009907374975 0.0 purine_nucleotide_binding GO:0017076 12133 1650 34 8 1997 12 1 false 0.9577584817543121 0.9577584817543121 0.0 ribonucleotide_binding GO:0032553 12133 1651 34 8 1997 12 1 false 0.958229610927025 0.958229610927025 0.0 antigen_processing_and_presentation_of_exogenous_peptide_antigen_via_MHC_class_I,_TAP-dependent GO:0002479 12133 70 34 1 73 1 1 false 0.9589041095890459 0.9589041095890459 1.607820438613435E-5 protein_modification_process GO:0036211 12133 2370 34 12 3518 23 2 false 0.9594649221828305 0.9594649221828305 0.0 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 34 3 149 3 1 false 0.9600036277888687 0.9600036277888687 9.06947215672054E-5 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 34 3 1225 4 2 false 0.9610558149612053 0.9610558149612053 5.928244845001387E-155 purine_nucleoside_binding GO:0001883 12133 1631 34 8 1639 8 1 false 0.961531589076234 0.961531589076234 7.876250956196666E-22 activation_of_adenylate_cyclase_activity GO:0007190 12133 50 34 1 52 1 1 false 0.9615384615384723 0.9615384615384723 7.54147812971345E-4 transcription,_DNA-dependent GO:0006351 12133 2643 34 13 4063 26 3 false 0.9632243258507542 0.9632243258507542 0.0 organophosphate_catabolic_process GO:0046434 12133 1000 34 5 2495 21 2 false 0.9642125791684496 0.9642125791684496 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 34 8 7256 32 1 false 0.9652776165012135 0.9652776165012135 0.0 apoptotic_process GO:0006915 12133 1373 34 4 1385 4 1 false 0.9657541518448847 0.9657541518448847 1.0085392941984968E-29 protein_phosphorylation GO:0006468 12133 1195 34 3 2577 12 2 false 0.9659509539239584 0.9659509539239584 0.0 striated_muscle_tissue_development GO:0014706 12133 285 34 1 295 1 1 false 0.9661016949152815 0.9661016949152815 8.482306621073292E-19 endoplasmic_reticulum GO:0005783 12133 854 34 1 8213 31 2 false 0.966965677174688 0.966965677174688 0.0 immunoglobulin_mediated_immune_response GO:0016064 12133 89 34 1 92 1 1 false 0.967391304347824 0.967391304347824 7.963051441312322E-6 purine_ribonucleoside_triphosphate_metabolic_process GO:0009205 12133 1001 34 5 1007 5 2 false 0.970503501092729 0.970503501092729 7.008686204750717E-16 purine_ribonucleoside_binding GO:0032550 12133 1629 34 8 1635 8 2 false 0.9709550845429742 0.9709550845429742 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 34 8 1639 8 1 false 0.9710252105572678 0.9710252105572678 3.7483303336303164E-17 carbohydrate_derivative_catabolic_process GO:1901136 12133 1036 34 5 2517 21 2 false 0.9712900425786617 0.9712900425786617 0.0 regulation_of_establishment_of_protein_localization GO:0070201 12133 306 34 1 1192 12 2 false 0.9721053178369563 0.9721053178369563 5.168872172755415E-294 response_to_external_stimulus GO:0009605 12133 1046 34 1 5200 16 1 false 0.9726548017392375 0.9726548017392375 0.0 neurological_system_process GO:0050877 12133 894 34 1 1272 3 1 false 0.973903358943313 0.973903358943313 0.0 nucleocytoplasmic_transport GO:0006913 12133 327 34 2 331 2 1 false 0.9759406756385482 0.9759406756385482 2.036102168267257E-9 integral_to_membrane GO:0016021 12133 2318 34 1 2375 1 1 false 0.9760000000014666 0.9760000000014666 3.0839384482043954E-116 cytoskeletal_part GO:0044430 12133 1031 34 2 5573 28 2 false 0.9763090242394068 0.9763090242394068 0.0 glycosyl_compound_catabolic_process GO:1901658 12133 956 34 5 2175 20 2 false 0.9769576719461421 0.9769576719461421 0.0 cation_binding GO:0043169 12133 2758 34 5 4448 13 1 false 0.9776555846855097 0.9776555846855097 0.0 viral_reproduction GO:0016032 12133 633 34 14 634 14 1 false 0.977917981072865 0.977917981072865 0.0015772870662463625 establishment_of_protein_localization_to_mitochondrion GO:0072655 12133 66 34 1 211 10 2 false 0.9787638876694273 0.9787638876694273 1.9619733177914497E-56 chromosome GO:0005694 12133 592 34 1 3226 19 1 false 0.9790163667458178 0.9790163667458178 0.0 mRNA_transport GO:0051028 12133 106 34 1 124 2 1 false 0.979937057435057 0.979937057435057 4.872659948511352E-22 epidermal_growth_factor_receptor_signaling_pathway GO:0007173 12133 197 34 2 199 2 1 false 0.9799502563321717 0.9799502563321717 5.075884472869322E-5 cation_transport GO:0006812 12133 606 34 1 833 3 1 false 0.9799577044093348 0.9799577044093348 4.047492354513465E-211 organonitrogen_compound_catabolic_process GO:1901565 12133 1133 34 5 2643 21 2 false 0.9800388055998707 0.9800388055998707 0.0 positive_regulation_of_ubiquitin-protein_ligase_activity_involved_in_mitotic_cell_cycle GO:0051437 12133 70 34 2 86 4 2 false 0.9806833352562416 0.9806833352562416 1.0344828145516245E-17 hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides GO:0016818 12133 1081 34 5 1085 5 1 false 0.9816686606152377 0.9816686606152377 1.7413918354446858E-11 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 34 12 4395 26 3 false 0.9830024978243068 0.9830024978243068 0.0 protein_import_into_nucleus GO:0006606 12133 200 34 1 690 12 5 false 0.9841883230033114 0.9841883230033114 1.1794689955817937E-179 virus-host_interaction GO:0019048 12133 355 34 5 588 14 2 false 0.9847653495268559 0.9847653495268559 1.0104535019427035E-170 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 34 24 7976 30 2 false 0.9850254783571072 0.9850254783571072 0.0 membrane-bounded_organelle GO:0043227 12133 7284 34 24 7980 30 1 false 0.9871903990505595 0.9871903990505595 0.0 cellular_component_morphogenesis GO:0032989 12133 810 34 1 5068 25 4 false 0.9872849375268175 0.9872849375268175 0.0 chordate_embryonic_development GO:0043009 12133 471 34 1 477 1 1 false 0.9874213836479633 0.9874213836479633 6.308586670641318E-14 cell_periphery GO:0071944 12133 2667 34 4 9983 33 1 false 0.9879046502625114 0.9879046502625114 0.0 cell_migration GO:0016477 12133 734 34 2 785 3 1 false 0.9880884523075354 0.9880884523075354 1.8763224028220524E-81 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 34 2 1546 12 3 false 0.9881874498124923 0.9881874498124923 0.0 ncRNA_processing GO:0034470 12133 186 34 1 649 13 2 false 0.9881947741239954 0.9881947741239954 4.048832162241149E-168 single-organism_metabolic_process GO:0044710 12133 2877 34 6 8027 32 1 false 0.9895901842165149 0.9895901842165149 0.0 regulation_of_gene_expression GO:0010468 12133 2935 34 14 4361 29 2 false 0.9898720098360763 0.9898720098360763 0.0 nucleotide_metabolic_process GO:0009117 12133 1317 34 6 1319 6 1 false 0.9909194554665322 0.9909194554665322 1.1504554077729292E-6 ion_transmembrane_transporter_activity GO:0015075 12133 469 34 1 589 3 2 false 0.9917114322325029 0.9917114322325029 1.1842155919657181E-128 epithelium_migration GO:0090132 12133 130 34 1 131 1 1 false 0.9923664122137256 0.9923664122137256 0.007633587786259341 protein_localization_to_nucleus GO:0034504 12133 233 34 2 516 12 1 false 0.9924974447292716 0.9924974447292716 1.4955266190313754E-153 purine-containing_compound_catabolic_process GO:0072523 12133 959 34 5 1651 16 6 false 0.9925741705952356 0.9925741705952356 0.0 homeostatic_process GO:0042592 12133 990 34 1 2082 8 1 false 0.9943425379439944 0.9943425379439944 0.0 response_to_other_organism GO:0051707 12133 475 34 2 1194 15 2 false 0.9948008185073371 0.9948008185073371 0.0 plasma_membrane GO:0005886 12133 2594 34 3 10252 33 3 false 0.9952516529124149 0.9952516529124149 0.0 nucleoside_catabolic_process GO:0009164 12133 952 34 5 1516 15 5 false 0.995264794934366 0.995264794934366 0.0 pyrophosphatase_activity GO:0016462 12133 1080 34 5 1081 5 1 false 0.995374653099011 0.995374653099011 9.250693802031629E-4 membrane GO:0016020 12133 4398 34 7 10701 33 1 false 0.9954086540595815 0.9954086540595815 0.0 nucleoside_phosphate_catabolic_process GO:1901292 12133 972 34 5 1587 16 3 false 0.9965532040772496 0.9965532040772496 0.0 cellular_protein_modification_process GO:0006464 12133 2370 34 12 3038 22 2 false 0.9965779407620958 0.9965779407620958 0.0 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 34 3 2849 20 1 false 0.9973104127532832 0.9973104127532832 0.0 cytoskeleton GO:0005856 12133 1430 34 3 3226 19 1 false 0.998214612841925 0.998214612841925 0.0 macromolecular_complex_assembly GO:0065003 12133 973 34 4 1603 15 2 false 0.998463293809742 0.998463293809742 0.0 protein_targeting_to_nucleus GO:0044744 12133 200 34 1 443 11 1 false 0.9987814760478192 0.9987814760478192 9.352491047681514E-132 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 34 12 3611 24 3 false 0.9988483915838317 0.9988483915838317 0.0 membrane_part GO:0044425 12133 2995 34 2 10701 33 2 false 0.9997318554368337 0.9997318554368337 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 34 11 3220 23 4 false 0.9998559205103993 0.9998559205103993 0.0 protein_complex_assembly GO:0006461 12133 743 34 2 1214 14 3 false 0.9999631744404414 0.9999631744404414 0.0 DNA_binding GO:0003677 12133 2091 34 6 2849 20 1 false 0.9999918817626077 0.9999918817626077 0.0 protein_complex GO:0043234 12133 2976 34 12 3462 25 1 false 0.9999990245629575 0.9999990245629575 0.0 GO:0000000 12133 11221 34 34 0 0 0 true 1.0 1.0 1.0 blood_circulation GO:0008015 12133 307 34 2 307 2 1 true 1.0 1.0 1.0 channel_activity GO:0015267 12133 304 34 1 304 1 1 true 1.0 1.0 1.0 ubiquitin_protein_ligase_binding GO:0031625 12133 147 34 1 147 1 1 true 1.0 1.0 1.0 melanosome GO:0042470 12133 87 34 2 87 2 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 34 3 1169 3 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 34 5 417 5 1 true 1.0 1.0 1.0 RNA_transport GO:0050658 12133 124 34 2 124 2 2 true 1.0 1.0 1.0