ID Pop.total Pop.term Study.total Study.term Pop.family Study.family nparents is.trivial p p.adjusted p.min Prp19_complex GO:0000974 12133 78 12 3 2976 5 1 false 1.6686113052900975E-4 1.6686113052900975E-4 3.570519754703887E-156 ribonucleoprotein_complex GO:0030529 12133 569 12 5 9264 11 2 false 2.909290528303779E-4 2.909290528303779E-4 0.0 RNA_binding GO:0003723 12133 763 12 7 2849 8 1 false 5.943785172066757E-4 5.943785172066757E-4 0.0 cytosolic_part GO:0044445 12133 178 12 3 5117 6 2 false 7.661689305201998E-4 7.661689305201998E-4 0.0 nucleic_acid_metabolic_process GO:0090304 12133 3799 12 12 6846 12 2 false 8.461072177412712E-4 8.461072177412712E-4 0.0 paraspeckles GO:0042382 12133 6 12 2 272 3 1 false 0.0012089091479148852 0.0012089091479148852 1.8794561691225117E-12 small_nuclear_ribonucleoprotein_complex GO:0030532 12133 93 12 3 3020 8 2 false 0.0014154768630709838 0.0014154768630709838 1.1070924240418437E-179 SCF_complex_assembly GO:0010265 12133 1 12 1 284 1 1 false 0.0035211267605635955 0.0035211267605635955 0.0035211267605635955 positive_regulation_of_RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0045899 12133 2 12 1 1043 2 4 false 0.0038332508285763628 0.0038332508285763628 1.8402548384908118E-6 translational_elongation GO:0006414 12133 121 12 3 3388 10 2 false 0.004437067804570412 0.004437067804570412 5.332026529203484E-226 spliceosomal_complex GO:0005681 12133 150 12 3 3020 8 2 false 0.005593416195829232 0.005593416195829232 2.455159410572961E-258 mRNA_metabolic_process GO:0016071 12133 573 12 6 3294 11 1 false 0.005663660184012288 0.005663660184012288 0.0 nitrogen_compound_metabolic_process GO:0006807 12133 5244 12 12 8027 12 1 false 0.006017494139199933 0.006017494139199933 0.0 nucleobase-containing_compound_metabolic_process GO:0006139 12133 4840 12 12 7341 12 5 false 0.006715237330553196 0.006715237330553196 0.0 organic_cyclic_compound_metabolic_process GO:1901360 12133 5047 12 12 7451 12 1 false 0.009289453842645167 0.009289453842645167 0.0 heterocycle_metabolic_process GO:0046483 12133 4933 12 12 7256 12 1 false 0.00970741115868793 0.00970741115868793 0.0 cellular_aromatic_compound_metabolic_process GO:0006725 12133 4940 12 12 7256 12 1 false 0.009874194384519154 0.009874194384519154 0.0 regulation_of_NIK/NF-kappaB_cascade GO:1901222 12133 17 12 1 1605 1 2 false 0.010591900311534702 0.010591900311534702 1.2442844653745033E-40 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0097201 12133 3 12 1 497 2 2 false 0.012048095021745484 0.012048095021745484 4.9170880611140405E-8 cellular_response_to_stress GO:0033554 12133 1124 12 4 4743 5 2 false 0.012736064382735007 0.012736064382735007 0.0 NIK/NF-kappaB_cascade GO:0038061 12133 24 12 1 1828 1 2 false 0.013129102844643043 0.013129102844643043 3.725046499789671E-55 cellular_nitrogen_compound_metabolic_process GO:0034641 12133 5073 12 12 7275 12 2 false 0.013166488863602669 0.013166488863602669 0.0 ribosomal_subunit GO:0044391 12133 132 12 2 7199 10 4 false 0.013636193461338215 0.013636193461338215 2.5906239763169356E-285 translational_initiation GO:0006413 12133 160 12 2 7667 9 2 false 0.014150405467275381 0.014150405467275381 0.0 nucleus GO:0005634 12133 4764 12 10 7259 10 1 false 0.014775357941716489 0.014775357941716489 0.0 membrane-enclosed_lumen GO:0031974 12133 3005 12 7 10701 11 1 false 0.014818834339128478 0.014818834339128478 0.0 RNA_metabolic_process GO:0016070 12133 3294 12 11 5627 12 2 false 0.015301276493237296 0.015301276493237296 0.0 nuclear_matrix GO:0016363 12133 81 12 2 2767 7 2 false 0.016156810560354028 0.016156810560354028 2.9785824972298125E-158 regulation_of_translational_fidelity GO:0006450 12133 9 12 1 2087 4 2 false 0.017150631657715312 0.017150631657715312 4.915442341416784E-25 cytoplasmic_pattern_recognition_receptor_signaling_pathway GO:0002753 12133 39 12 1 1977 1 3 false 0.019726858877069247 0.019726858877069247 8.49513097758148E-83 RNA_processing GO:0006396 12133 601 12 5 3762 11 2 false 0.02044693858563503 0.02044693858563503 0.0 protein_targeting_to_ER GO:0045047 12133 104 12 2 721 2 3 false 0.020634920634926453 0.020634920634926453 1.514347826459292E-128 cellular_metabolic_process GO:0044237 12133 7256 12 12 10007 12 2 false 0.021068495844843056 0.021068495844843056 0.0 IkappaB_kinase_complex GO:0008385 12133 10 12 1 3063 7 2 false 0.022652771420627583 0.022652771420627583 5.066173975414688E-29 nuclear_periphery GO:0034399 12133 97 12 2 2767 7 2 false 0.02276967340250533 0.02276967340250533 7.041791399430774E-182 gene_expression GO:0010467 12133 3708 12 11 6052 12 1 false 0.023922670896722502 0.023922670896722502 0.0 translation_regulator_activity GO:0045182 12133 21 12 1 10260 12 2 false 0.024299668512097868 0.024299668512097868 3.0418957762761004E-65 DNA-dependent_transcriptional_preinitiation_complex_assembly GO:0070897 12133 9 12 1 338 1 2 false 0.026627218934908582 0.026627218934908582 7.01716404793524E-18 biosynthetic_process GO:0009058 12133 4179 12 10 8027 12 1 false 0.026877621272245 0.026877621272245 0.0 cellular_macromolecule_metabolic_process GO:0044260 12133 5613 12 12 7569 12 2 false 0.027577646955540394 0.027577646955540394 0.0 homeostasis_of_number_of_cells GO:0048872 12133 166 12 2 990 2 1 false 0.0279743849005746 0.0279743849005746 1.128853988781411E-193 establishment_of_protein_localization_to_organelle GO:0072594 12133 210 12 2 1239 2 2 false 0.02861367432436556 0.02861367432436556 4.427655683668096E-244 alternative_mRNA_splicing,_via_spliceosome GO:0000380 12133 21 12 2 202 3 1 false 0.029067533619031572 0.029067533619031572 5.801734415928739E-29 macromolecule_biosynthetic_process GO:0009059 12133 3475 12 10 6537 12 2 false 0.031870612011281156 0.031870612011281156 0.0 macromolecular_complex GO:0032991 12133 3462 12 7 10701 11 1 false 0.032769180106047124 0.032769180106047124 0.0 translesion_synthesis GO:0019985 12133 9 12 1 273 1 2 false 0.03296703296702927 0.03296703296702927 4.922351021851153E-17 protein_targeting GO:0006605 12133 443 12 2 2378 2 2 false 0.0346405647335603 0.0346405647335603 0.0 protein_domain_specific_binding GO:0019904 12133 486 12 3 6397 10 1 false 0.034958132360977695 0.034958132360977695 0.0 ribosome GO:0005840 12133 210 12 2 6755 10 3 false 0.036724203030757296 0.036724203030757296 0.0 nuclear_body GO:0016604 12133 272 12 3 805 3 1 false 0.038294330810311944 0.038294330810311944 8.12188174084084E-223 ribosome_assembly GO:0042255 12133 16 12 1 417 1 3 false 0.03836930455635346 0.03836930455635346 3.349634512578164E-29 regulation_of_DNA-dependent_transcription,_initiation GO:2000142 12133 15 12 1 2670 7 3 false 0.03871200517004074 0.03871200517004074 5.444282950561458E-40 multi-organism_cellular_process GO:0044764 12133 634 12 3 9702 12 2 false 0.03921076800853335 0.03921076800853335 0.0 organelle GO:0043226 12133 7980 12 11 10701 11 1 false 0.0395915136116988 0.0395915136116988 0.0 mRNA_binding GO:0003729 12133 91 12 3 763 7 1 false 0.040216567697253014 0.040216567697253014 1.7788235024198917E-120 RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0051123 12133 8 12 1 196 1 2 false 0.040816326530613685 0.040816326530613685 2.1395419233362556E-14 regulation_of_transcription_initiation_from_RNA_polymerase_II_promoter GO:0060260 12133 13 12 1 1243 4 3 false 0.04123155362272684 0.04123155362272684 3.9219319072235074E-31 metabolic_process GO:0008152 12133 8027 12 12 10446 12 1 false 0.04230690777492248 0.04230690777492248 0.0 positive_regulation_of_RNA_splicing GO:0033120 12133 9 12 1 1248 6 3 false 0.04258043708364663 0.04258043708364663 5.0861367032521447E-23 cellular_macromolecule_biosynthetic_process GO:0034645 12133 3388 12 10 6146 12 3 false 0.042769665601416415 0.042769665601416415 0.0 organic_substance_biosynthetic_process GO:1901576 12133 4134 12 10 7470 12 2 false 0.044161333411797066 0.044161333411797066 0.0 TBP-class_protein_binding GO:0017025 12133 16 12 1 715 2 1 false 0.04428512663806981 0.04428512663806981 5.310604856356121E-33 ribosomal_small_subunit_assembly GO:0000028 12133 6 12 1 128 1 3 false 0.0468749999999994 0.0468749999999994 1.8437899825856603E-10 isoleucyl-tRNA_aminoacylation GO:0006428 12133 2 12 1 42 1 1 false 0.047619047619047894 0.047619047619047894 0.0011614401858304456 cellular_biosynthetic_process GO:0044249 12133 4077 12 10 7290 12 2 false 0.04802996834891966 0.04802996834891966 0.0 cellular_component_disassembly GO:0022411 12133 351 12 2 7663 8 2 false 0.04877683502177421 0.04877683502177421 0.0 activation_of_NF-kappaB-inducing_kinase_activity GO:0007250 12133 16 12 1 319 1 5 false 0.050156739811908914 0.050156739811908914 2.6671768240247182E-27 protein_localization_to_endoplasmic_reticulum GO:0070972 12133 116 12 2 516 2 1 false 0.05019944306464037 0.05019944306464037 8.917305549619806E-119 isoleucine-tRNA_ligase_activity GO:0004822 12133 2 12 1 39 1 1 false 0.051282051282051065 0.051282051282051065 0.0013495276653171407 viral_transcription GO:0019083 12133 145 12 2 2964 8 3 false 0.05481342690658429 0.05481342690658429 1.0927707330622845E-250 ligase_activity GO:0016874 12133 504 12 2 4901 4 1 false 0.05501686992568239 0.05501686992568239 0.0 euchromatin GO:0000791 12133 16 12 1 287 1 1 false 0.05574912891985731 0.05574912891985731 1.511666228254712E-26 posttranscriptional_regulation_of_gene_expression GO:0010608 12133 349 12 3 2935 8 1 false 0.05915423007512604 0.05915423007512604 0.0 supraspliceosomal_complex GO:0044530 12133 3 12 1 150 3 1 false 0.059196444766916344 0.059196444766916344 1.813894431344149E-6 cytosol GO:0005829 12133 2226 12 5 5117 6 1 false 0.059481069416505515 0.059481069416505515 0.0 heterocyclic_compound_binding GO:1901363 12133 4359 12 9 8962 12 1 false 0.060585507230542644 0.060585507230542644 0.0 intracellular_receptor_signaling_pathway GO:0030522 12133 217 12 1 3547 1 1 false 0.06117846067094489 0.06117846067094489 0.0 intracellular_organelle_lumen GO:0070013 12133 2919 12 7 5320 8 2 false 0.06212849337946142 0.06212849337946142 0.0 chromatin_binding GO:0003682 12133 309 12 2 8962 12 1 false 0.062266237355118714 0.062266237355118714 0.0 organelle_lumen GO:0043233 12133 2968 12 7 5401 8 2 false 0.06271389131357011 0.06271389131357011 0.0 microtubule_organizing_center_organization GO:0031023 12133 66 12 1 2031 2 2 false 0.06395209232275552 0.06395209232275552 7.775037316859227E-126 organic_cyclic_compound_binding GO:0097159 12133 4407 12 9 8962 12 1 false 0.06521107253055053 0.06521107253055053 0.0 leukocyte_homeostasis GO:0001776 12133 55 12 1 1628 2 2 false 0.06644628648319506 0.06644628648319506 7.300149261907148E-104 negative_regulation_of_mRNA_processing GO:0050686 12133 13 12 1 1096 6 3 false 0.0692440393961658 0.0692440393961658 2.031276795679201E-30 NF-kappaB-inducing_kinase_activity GO:0004704 12133 21 12 1 301 1 2 false 0.06976744186045904 0.06976744186045904 9.301787616944151E-33 ribosomal_small_subunit_biogenesis GO:0042274 12133 17 12 1 243 1 2 false 0.06995884773662231 0.06995884773662231 1.7559807727942103E-26 C2H2_zinc_finger_domain_binding GO:0070742 12133 12 12 1 486 3 1 false 0.07240561398633864 0.07240561398633864 3.163375599680073E-24 translation GO:0006412 12133 457 12 3 5433 12 3 false 0.0734492510971314 0.0734492510971314 0.0 aminoacyl-tRNA_editing_activity GO:0002161 12133 7 12 1 94 1 2 false 0.07446808510638464 0.07446808510638464 9.769567241723248E-11 extracellular_organelle GO:0043230 12133 59 12 1 8358 11 2 false 0.07500999293251341 0.07500999293251341 6.7158083402639515E-152 extracellular_vesicular_exosome GO:0070062 12133 58 12 1 763 1 2 false 0.07601572739186654 0.07601572739186654 1.4131645972383266E-88 maturation_of_SSU-rRNA GO:0030490 12133 8 12 1 104 1 2 false 0.0769230769230749 0.0769230769230749 3.8823564737710265E-12 nucleolus GO:0005730 12133 1357 12 5 4208 8 3 false 0.07708264189982546 0.07708264189982546 0.0 signal_transduction_by_phosphorylation GO:0023014 12133 307 12 1 3947 1 2 false 0.07778059285539617 0.07778059285539617 0.0 extracellular_membrane-bounded_organelle GO:0065010 12133 59 12 1 7284 10 2 false 0.07815646562489487 0.07815646562489487 2.3146567535480854E-148 macromolecule_metabolic_process GO:0043170 12133 6052 12 12 7451 12 1 false 0.08228524787381221 0.08228524787381221 0.0 structural_constituent_of_ribosome GO:0003735 12133 152 12 2 526 2 1 false 0.08311424950212103 0.08311424950212103 1.18011379183299E-136 negative_regulation_of_RNA_splicing GO:0033119 12133 15 12 1 1037 6 3 false 0.08390543742996738 0.08390543742996738 8.39457188486895E-34 translational_termination GO:0006415 12133 92 12 2 513 3 2 false 0.08439540274772764 0.08439540274772764 3.4634519853301643E-104 postreplication_repair GO:0006301 12133 16 12 1 368 2 1 false 0.08517948110413029 0.08517948110413029 2.574562678585272E-28 positive_regulation_of_mRNA_processing GO:0050685 12133 19 12 1 1291 6 3 false 0.08527694588944013 0.08527694588944013 1.0846695642468986E-42 immune_response-regulating_signaling_pathway GO:0002764 12133 310 12 1 3626 1 2 false 0.08549365692207408 0.08549365692207408 0.0 nuclear_euchromatin GO:0005719 12133 13 12 1 152 1 2 false 0.08552631578947 0.08552631578947 4.566130539711244E-19 RNA_catabolic_process GO:0006401 12133 203 12 2 4368 11 3 false 0.08970313315598366 0.08970313315598366 0.0 regulation_of_translation GO:0006417 12133 210 12 2 3605 9 4 false 0.09277755789232484 0.09277755789232484 0.0 immune_response-regulating_cell_surface_receptor_signaling_pathway GO:0002768 12133 188 12 1 2025 1 2 false 0.09283950617287755 0.09283950617287755 5.184659787643375E-271 core_promoter_binding GO:0001047 12133 57 12 1 1169 2 1 false 0.09518145704684407 0.09518145704684407 2.2132764176966058E-98 positive_regulation_of_mRNA_splicing,_via_spliceosome GO:0048026 12133 7 12 1 213 3 4 false 0.09582326292548851 0.09582326292548851 2.799196300608397E-13 nuclear_part GO:0044428 12133 2767 12 7 6936 11 2 false 0.09787384617165865 0.09787384617165865 0.0 regulation_of_DNA-dependent_transcription_in_response_to_stress GO:0043620 12133 41 12 1 3208 8 2 false 0.09788795859042249 0.09788795859042249 7.591030632914061E-95 cellular_response_to_interleukin-1 GO:0071347 12133 39 12 1 397 1 2 false 0.09823677581863896 0.09823677581863896 6.2361767471504674E-55 regulation_of_biosynthetic_process GO:0009889 12133 3012 12 8 5483 10 2 false 0.09861581698683664 0.09861581698683664 0.0 cellular_response_to_oxygen_levels GO:0071453 12133 85 12 1 1663 2 2 false 0.09964159417878483 0.09964159417878483 4.192529980934564E-145 macromolecular_complex_disassembly GO:0032984 12133 199 12 2 1380 4 2 false 0.1018138624698696 0.1018138624698696 1.9082717261040364E-246 macromolecular_complex_subunit_organization GO:0043933 12133 1256 12 4 3745 6 1 false 0.1019947567497495 0.1019947567497495 0.0 non-membrane-bounded_organelle GO:0043228 12133 3226 12 7 7980 11 1 false 0.1045144037155584 0.1045144037155584 0.0 intracellular_non-membrane-bounded_organelle GO:0043232 12133 3226 12 7 7958 11 2 false 0.10593924142836711 0.10593924142836711 0.0 membrane_protein_proteolysis GO:0033619 12133 40 12 1 732 2 1 false 0.10637423097340896 0.10637423097340896 6.346448178672535E-67 protein_targeting_to_membrane GO:0006612 12133 145 12 2 443 2 1 false 0.10663616028109703 0.10663616028109703 5.648405296311656E-121 protein_complex_disassembly GO:0043241 12133 154 12 2 1031 4 2 false 0.10835158570942582 0.10835158570942582 4.7545827865276796E-188 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061428 12133 3 12 1 27 1 2 false 0.11111111111111109 0.11111111111111109 3.418803418803417E-4 cellular_process_involved_in_reproduction GO:0048610 12133 469 12 2 9699 12 2 false 0.1118189441946074 0.1118189441946074 0.0 carboxylic_ester_hydrolase_activity GO:0052689 12133 92 12 1 814 1 1 false 0.11302211302208236 0.11302211302208236 4.359236908507715E-124 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_stress GO:0043618 12133 36 12 1 1199 4 2 false 0.11493590958007714 0.11493590958007714 9.194442294553035E-70 nucleic_acid_binding GO:0003676 12133 2849 12 8 4407 9 2 false 0.11653729576262203 0.11653729576262203 0.0 organelle_part GO:0044422 12133 5401 12 8 10701 11 2 false 0.11935780121593345 0.11935780121593345 0.0 regulation_of_cellular_metabolic_process GO:0031323 12133 3974 12 8 8688 12 3 false 0.12192382786106516 0.12192382786106516 0.0 structural_molecule_activity GO:0005198 12133 526 12 2 10257 12 1 false 0.12337132548070459 0.12337132548070459 0.0 catalytic_step_2_spliceosome GO:0071013 12133 76 12 3 151 3 3 false 0.12498333259256493 0.12498333259256493 5.422089502503699E-45 protein_N-terminus_binding GO:0047485 12133 85 12 1 6397 10 1 false 0.12528774128742287 0.12528774128742287 1.5319897739448716E-195 small_molecule_binding GO:0036094 12133 2102 12 5 8962 12 1 false 0.127267901497365 0.127267901497365 0.0 response_to_abiotic_stimulus GO:0009628 12133 676 12 2 5200 5 1 false 0.12911653507180498 0.12911653507180498 0.0 response_to_interleukin-1 GO:0070555 12133 60 12 1 461 1 1 false 0.13015184381777165 0.13015184381777165 6.955751367016218E-77 amino_acid_activation GO:0043038 12133 44 12 1 337 1 1 false 0.1305637982195888 0.1305637982195888 3.048791381604643E-56 myeloid_cell_homeostasis GO:0002262 12133 111 12 1 1628 2 2 false 0.13175392523893256 0.13175392523893256 2.626378318706563E-175 regulation_of_translational_elongation GO:0006448 12133 15 12 1 308 3 2 false 0.13953552993595475 0.13953552993595475 8.683071731337218E-26 positive_regulation_of_defense_response GO:0031349 12133 229 12 1 1621 1 3 false 0.1412708204811983 0.1412708204811983 6.85443065618377E-286 regulation_of_mRNA_processing GO:0050684 12133 49 12 1 3175 10 3 false 0.14423255506486352 0.14423255506486352 2.292701139367024E-109 multi-organism_process GO:0051704 12133 1180 12 3 10446 12 1 false 0.14595053093334184 0.14595053093334184 0.0 establishment_of_protein_localization GO:0045184 12133 1153 12 2 3010 2 2 false 0.14665372652778502 0.14665372652778502 0.0 ligase_activity,_forming_carbon-oxygen_bonds GO:0016875 12133 39 12 1 504 2 1 false 0.1489160276437153 0.1489160276437153 3.7172333696305043E-59 negative_regulation_of_mRNA_splicing,_via_spliceosome GO:0048025 12133 11 12 1 207 3 4 false 0.15179469228208897 0.15179469228208897 1.749347829328537E-18 positive_regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051091 12133 312 12 1 2035 1 3 false 0.15331695331706396 0.15331695331706396 0.0 regulation_of_RNA_splicing GO:0043484 12133 52 12 1 3151 10 3 false 0.1534990533339417 0.1534990533339417 1.4828410310444421E-114 intracellular_protein_transport GO:0006886 12133 658 12 2 1672 2 3 false 0.1547314303387378 0.1547314303387378 0.0 mRNA_5'-UTR_binding GO:0048027 12133 5 12 1 91 3 1 false 0.15759147219821418 0.15759147219821418 2.1503314800486076E-8 ubiquitin_ligase_complex GO:0000151 12133 147 12 1 9248 11 2 false 0.16167488735240226 0.16167488735240226 0.0 regulation_of_protein_stability GO:0031647 12133 99 12 1 2240 4 2 false 0.16551074716979436 0.16551074716979436 1.7785498552391114E-175 intracellular_transport GO:0046907 12133 1148 12 2 2815 2 2 false 0.16622747717878927 0.16622747717878927 0.0 regulation_of_metabolic_process GO:0019222 12133 4469 12 8 9189 12 2 false 0.16836706070346538 0.16836706070346538 0.0 regulation_of_cellular_biosynthetic_process GO:0031326 12133 2988 12 8 4972 10 3 false 0.16859149536166557 0.16859149536166557 0.0 cytokine_production GO:0001816 12133 362 12 1 4095 2 1 false 0.16900601434027215 0.16900601434027215 0.0 multi-organism_reproductive_process GO:0044703 12133 707 12 3 1275 3 1 false 0.17017870535712554 0.17017870535712554 0.0 reproductive_process GO:0022414 12133 1275 12 3 10446 12 2 false 0.17285450474803946 0.17285450474803946 0.0 cellular_macromolecule_localization GO:0070727 12133 918 12 2 2206 2 2 false 0.1730604843933543 0.1730604843933543 0.0 response_to_stress GO:0006950 12133 2540 12 4 5200 5 1 false 0.17328968014072593 0.17328968014072593 0.0 nuclear_lumen GO:0031981 12133 2490 12 7 3186 7 2 false 0.17777621015662515 0.17777621015662515 0.0 protein_modification_by_small_protein_conjugation_or_removal GO:0070647 12133 645 12 2 2370 3 1 false 0.18177083160313956 0.18177083160313956 0.0 viral_genome_expression GO:0019080 12133 153 12 2 557 3 2 false 0.1844199520290481 0.1844199520290481 1.6461772406083414E-141 aromatic_compound_biosynthetic_process GO:0019438 12133 3245 12 9 5597 12 2 false 0.18456976574694034 0.18456976574694034 0.0 heterocycle_biosynthetic_process GO:0018130 12133 3248 12 9 5588 12 2 false 0.18734154869225406 0.18734154869225406 0.0 organic_cyclic_compound_biosynthetic_process GO:1901362 12133 3310 12 9 5686 12 2 false 0.1890295131494178 0.1890295131494178 0.0 cellular_nitrogen_compound_biosynthetic_process GO:0044271 12133 3289 12 9 5629 12 2 false 0.19317941741173134 0.19317941741173134 0.0 reproduction GO:0000003 12133 1345 12 3 10446 12 1 false 0.19368300040959113 0.19368300040959113 0.0 positive_regulation_of_transferase_activity GO:0051347 12133 445 12 1 2275 1 3 false 0.1956043956045327 0.1956043956045327 0.0 type_I_interferon_production GO:0032606 12133 71 12 1 362 1 1 false 0.19613259668509953 0.19613259668509953 2.8677775679244762E-77 binding GO:0005488 12133 8962 12 12 10257 12 1 false 0.19779298233975218 0.19779298233975218 0.0 RNA_splicing GO:0008380 12133 307 12 4 601 5 1 false 0.20026907901685778 0.20026907901685778 4.262015823312228E-180 nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_signaling_pathway GO:0035872 12133 44 12 1 217 1 1 false 0.20276497695851403 0.20276497695851403 4.514459380304185E-47 positive_regulation_of_type_I_interferon_production GO:0032481 12133 41 12 1 201 1 3 false 0.20398009950248341 0.20398009950248341 9.949481941404742E-44 regulation_of_type_I_interferon_production GO:0032479 12133 67 12 1 325 1 2 false 0.2061538461538324 0.2061538461538324 2.788484219003069E-71 regulation_of_cytokine_production GO:0001817 12133 323 12 1 1562 1 2 false 0.20678617157496743 0.20678617157496743 0.0 ncRNA_metabolic_process GO:0034660 12133 258 12 2 3294 11 1 false 0.21101755938802533 0.21101755938802533 0.0 positive_regulation_of_signal_transduction GO:0009967 12133 782 12 1 3650 1 5 false 0.2142465753423095 0.2142465753423095 0.0 regulation_of_immune_response GO:0050776 12133 533 12 1 2461 1 3 false 0.21657862657461321 0.21657862657461321 0.0 regulation_of_protein_complex_assembly GO:0043254 12133 185 12 1 1610 2 3 false 0.2166732934695749 0.2166732934695749 1.34790682725651E-248 macromolecule_localization GO:0033036 12133 1642 12 2 3467 2 1 false 0.2242329000608495 0.2242329000608495 0.0 establishment_of_protein_localization_to_endoplasmic_reticulum GO:0072599 12133 105 12 2 220 2 2 false 0.2266500622665038 0.2266500622665038 1.3850176335002185E-65 cytosolic_ribosome GO:0022626 12133 92 12 2 296 3 2 false 0.22893135266014145 0.22893135266014145 4.2784789004852985E-79 intracellular_organelle GO:0043229 12133 7958 12 11 9096 11 2 false 0.22967434311227775 0.22967434311227775 0.0 positive_regulation_of_phosphate_metabolic_process GO:0045937 12133 640 12 1 2776 1 3 false 0.23054755043212932 0.23054755043212932 0.0 I-kappaB_kinase/NF-kappaB_cascade GO:0007249 12133 194 12 1 835 1 2 false 0.23233532934123596 0.23233532934123596 8.0742416973675315E-196 cellular_response_to_hypoxia GO:0071456 12133 79 12 1 1210 4 3 false 0.23694083245047934 0.23694083245047934 3.484581288071841E-126 positive_regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043123 12133 124 12 1 522 1 3 false 0.23754789272030183 0.23754789272030183 1.2617392241842968E-123 regulation_of_primary_metabolic_process GO:0080090 12133 3921 12 8 7507 12 2 false 0.23965663173721322 0.23965663173721322 0.0 positive_regulation_of_innate_immune_response GO:0045089 12133 178 12 1 740 1 4 false 0.24054054054061982 0.24054054054061982 1.4450011889246649E-176 positive_regulation_of_immune_response GO:0050778 12133 394 12 1 1600 1 4 false 0.2462500000001151 0.2462500000001151 0.0 regulation_of_macromolecule_biosynthetic_process GO:0010556 12133 2834 12 8 4395 10 3 false 0.2502765929091272 0.2502765929091272 0.0 tRNA_aminoacylation_for_protein_translation GO:0006418 12133 42 12 1 457 3 2 false 0.2516477821384476 0.2516477821384476 1.8852854762051817E-60 cellular_component_organization_or_biogenesis GO:0071840 12133 3839 12 6 10446 12 1 false 0.2527165892577308 0.2527165892577308 0.0 response_to_cytokine_stimulus GO:0034097 12133 461 12 1 1783 1 1 false 0.25855300056076075 0.25855300056076075 0.0 regulation_of_innate_immune_response GO:0045088 12133 226 12 1 868 1 3 false 0.2603686635943898 0.2603686635943898 2.196344369914344E-215 nucleoplasm GO:0005654 12133 1443 12 5 2767 7 2 false 0.2630539475801842 0.2630539475801842 0.0 regulation_of_I-kappaB_kinase/NF-kappaB_cascade GO:0043122 12133 171 12 1 650 1 2 false 0.26307692307691666 0.26307692307691666 6.010278185218431E-162 intracellular_organelle_part GO:0044446 12133 5320 12 8 9083 11 3 false 0.26337742781807605 0.26337742781807605 0.0 inflammatory_response GO:0006954 12133 381 12 1 1437 1 2 false 0.2651356993735921 0.2651356993735921 0.0 positive_regulation_of_metabolic_process GO:0009893 12133 1872 12 4 8366 12 3 false 0.27185263057748144 0.27185263057748144 0.0 cellular_response_to_cytokine_stimulus GO:0071345 12133 381 12 1 1398 1 2 false 0.27253218884109986 0.27253218884109986 0.0 regulation_of_biological_quality GO:0065008 12133 2082 12 4 6908 9 1 false 0.273427568674202 0.273427568674202 0.0 immune_system_development GO:0002520 12133 521 12 1 3460 2 2 false 0.2785193020800316 0.2785193020800316 0.0 organelle_assembly GO:0070925 12133 210 12 1 2677 4 2 false 0.2788922231219993 0.2788922231219993 7.5039E-319 response_to_hypoxia GO:0001666 12133 200 12 1 2540 4 2 false 0.2798204320118983 0.2798204320118983 2.6634431659671552E-303 positive_regulation_of_cytokine_production GO:0001819 12133 175 12 1 614 1 3 false 0.2850162866449984 0.2850162866449984 1.2195240299259301E-158 positive_regulation_of_protein_serine/threonine_kinase_activity GO:0071902 12133 244 12 1 856 1 3 false 0.285046728972063 0.285046728972063 2.175375701359491E-221 protein_binding GO:0005515 12133 6397 12 10 8962 12 1 false 0.28711361547267034 0.28711361547267034 0.0 myeloid_cell_differentiation GO:0030099 12133 237 12 1 2177 3 2 false 0.29245065971870254 0.29245065971870254 0.0 protein_metabolic_process GO:0019538 12133 3431 12 7 7395 12 2 false 0.29381267338475736 0.29381267338475736 0.0 negative_regulation_of_nitrogen_compound_metabolic_process GO:0051172 12133 872 12 3 5447 12 3 false 0.2992285045312092 0.2992285045312092 0.0 establishment_of_localization_in_cell GO:0051649 12133 1633 12 2 2978 2 2 false 0.3006095760355315 0.3006095760355315 0.0 signal_transducer_activity GO:0004871 12133 1070 12 1 3547 1 2 false 0.3016633775017475 0.3016633775017475 0.0 positive_regulation_of_cellular_metabolic_process GO:0031325 12133 1786 12 4 7638 12 4 false 0.3017296379822581 0.3017296379822581 0.0 regulation_of_biological_process GO:0050789 12133 6622 12 9 10446 12 2 false 0.3044061936327156 0.3044061936327156 0.0 intrinsic_to_plasma_membrane GO:0031226 12133 826 12 1 2695 1 2 false 0.3064935064932849 0.3064935064932849 0.0 negative_regulation_of_metabolic_process GO:0009892 12133 1354 12 3 8327 12 3 false 0.3081307633306146 0.3081307633306146 0.0 regulation_of_defense_response GO:0031347 12133 387 12 1 1253 1 2 false 0.3088587390262929 0.3088587390262929 0.0 transcription_factor_binding GO:0008134 12133 715 12 2 6397 10 1 false 0.30969534302317414 0.30969534302317414 0.0 hematopoietic_or_lymphoid_organ_development GO:0048534 12133 491 12 1 2896 2 3 false 0.3103917976310433 0.3103917976310433 0.0 microtubule_cytoskeleton_organization GO:0000226 12133 259 12 1 831 1 2 false 0.31167268351379257 0.31167268351379257 4.0880234187670296E-223 primary_metabolic_process GO:0044238 12133 7288 12 12 8027 12 1 false 0.3135441935948371 0.3135441935948371 0.0 regulation_of_transcription_from_RNA_polymerase_II_promoter_in_response_to_hypoxia GO:0061418 12133 27 12 1 86 1 2 false 0.3139534883720948 0.3139534883720948 6.233113581740502E-23 regulation_of_macromolecule_metabolic_process GO:0060255 12133 3683 12 8 6638 12 2 false 0.31632643947825134 0.31632643947825134 0.0 receptor_signaling_protein_activity GO:0005057 12133 339 12 1 1070 1 1 false 0.3168224299066703 0.3168224299066703 2.5248591221043436E-289 negative_regulation_of_cellular_metabolic_process GO:0031324 12133 1256 12 3 7606 12 4 false 0.3170860703884754 0.3170860703884754 0.0 protein_localization_to_organelle GO:0033365 12133 516 12 2 914 2 1 false 0.31844904982969807 0.31844904982969807 5.634955900168089E-271 hydrolase_activity,_acting_on_ester_bonds GO:0016788 12133 814 12 1 2556 1 1 false 0.31846635367820275 0.31846635367820275 0.0 DNA_repair GO:0006281 12133 368 12 2 977 3 2 false 0.3185690038606388 0.3185690038606388 3.284245924949814E-280 organic_substance_transport GO:0071702 12133 1580 12 2 2783 2 1 false 0.3222321618390028 0.3222321618390028 0.0 response_to_DNA_damage_stimulus GO:0006974 12133 570 12 3 1124 4 1 false 0.32292682831574127 0.32292682831574127 0.0 nucleobase-containing_compound_biosynthetic_process GO:0034654 12133 3200 12 9 4989 12 5 false 0.3235522165295586 0.3235522165295586 0.0 mRNA_processing GO:0006397 12133 374 12 4 763 6 2 false 0.32484087270652506 0.32484087270652506 8.270510506831645E-229 viral_infectious_cycle GO:0019058 12133 213 12 2 557 3 1 false 0.32656047804770716 0.32656047804770716 3.455075709157513E-160 ribonucleoprotein_complex_assembly GO:0022618 12133 117 12 1 646 2 3 false 0.32965656274760613 0.32965656274760613 4.631331466925404E-132 ribonucleoprotein_complex_subunit_organization GO:0071826 12133 120 12 1 1256 4 1 false 0.3311400614373422 0.3311400614373422 3.1457660386089413E-171 nucleoplasm_part GO:0044451 12133 805 12 3 2767 7 2 false 0.3323421655883092 0.3323421655883092 0.0 regulation_of_RNA_polymerase_II_transcriptional_preinitiation_complex_assembly GO:0045898 12133 5 12 1 15 1 2 false 0.33333333333333326 0.33333333333333326 3.330003330003327E-4 regulation_of_cellular_process GO:0050794 12133 6304 12 9 9757 12 2 false 0.33605921016556195 0.33605921016556195 0.0 negative_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045934 12133 858 12 3 5032 12 4 false 0.33620959630480307 0.33620959630480307 0.0 cytoplasmic_transport GO:0016482 12133 666 12 2 1148 2 1 false 0.3363493312352984 0.3363493312352984 0.0 microtubule-based_process GO:0007017 12133 378 12 1 7541 8 1 false 0.337412972464428 0.337412972464428 0.0 molecular_function GO:0003674 12133 10257 12 12 11221 12 1 false 0.3401145938773203 0.3401145938773203 0.0 integral_to_plasma_membrane GO:0005887 12133 801 12 1 2339 1 2 false 0.3424540401883036 0.3424540401883036 0.0 intracellular_part GO:0044424 12133 9083 12 11 9983 11 2 false 0.353519534679978 0.353519534679978 0.0 regulation_of_cellular_component_biogenesis GO:0044087 12133 326 12 1 6813 9 2 false 0.35696567236048055 0.35696567236048055 0.0 regulation_of_cellular_protein_metabolic_process GO:0032268 12133 1247 12 3 5303 9 3 false 0.35773053019569334 0.35773053019569334 0.0 viral_reproductive_process GO:0022415 12133 557 12 3 783 3 2 false 0.3594209774178282 0.3594209774178282 1.4346997744229993E-203 cellular_macromolecule_catabolic_process GO:0044265 12133 672 12 2 6457 12 3 false 0.3597476802754667 0.3597476802754667 0.0 regulation_of_mRNA_splicing,_via_spliceosome GO:0048024 12133 32 12 1 231 3 3 false 0.36201687054158715 0.36201687054158715 5.789429371590664E-40 erythrocyte_differentiation GO:0030218 12133 88 12 1 243 1 2 false 0.3621399176954674 0.3621399176954674 1.540826297870933E-68 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0000122 12133 476 12 2 1541 4 3 false 0.3639703934506761 0.3639703934506761 0.0 positive_regulation_of_multicellular_organismal_process GO:0051240 12133 448 12 1 5157 5 3 false 0.3652866585310961 0.3652866585310961 0.0 regulation_of_intracellular_protein_kinase_cascade GO:0010627 12133 632 12 1 1730 1 2 false 0.3653179190749695 0.3653179190749695 0.0 positive_regulation_of_kinase_activity GO:0033674 12133 438 12 1 1181 1 3 false 0.37087214225224796 0.37087214225224796 0.0 mRNA_splicing,_via_spliceosome GO:0000398 12133 202 12 3 374 4 2 false 0.3741138262458681 0.3741138262458681 2.0954491420584897E-111 positive_regulation_of_protein_kinase_activity GO:0045860 12133 417 12 1 1112 1 4 false 0.37500000000008227 0.37500000000008227 1.302733E-318 activation_of_immune_response GO:0002253 12133 341 12 1 1618 2 2 false 0.377193646309043 0.377193646309043 0.0 biological_regulation GO:0065007 12133 6908 12 9 10446 12 1 false 0.3777633874007583 0.3777633874007583 0.0 positive_regulation_of_phosphorylation GO:0042327 12133 563 12 1 1487 1 3 false 0.37861466039011715 0.37861466039011715 0.0 cellular_component_assembly GO:0022607 12133 1392 12 3 3836 6 2 false 0.37902745651538516 0.37902745651538516 0.0 cellular_response_to_decreased_oxygen_levels GO:0036294 12133 79 12 1 207 1 2 false 0.38164251207729816 0.38164251207729816 2.976076769798144E-59 protein_complex_subunit_organization GO:0071822 12133 989 12 4 1256 4 1 false 0.3839417420653709 0.3839417420653709 2.2763776011987297E-281 nucleoside_phosphate_binding GO:1901265 12133 1998 12 5 4407 9 2 false 0.3864652673196734 0.3864652673196734 0.0 positive_regulation_of_cell_death GO:0010942 12133 383 12 1 3330 4 3 false 0.3867439576004004 0.3867439576004004 0.0 protein-DNA_complex_subunit_organization GO:0071824 12133 147 12 1 1256 4 1 false 0.39257581216047 0.39257581216047 3.54580927907897E-196 response_to_biotic_stimulus GO:0009607 12133 494 12 1 5200 5 1 false 0.3930468471211238 0.3930468471211238 0.0 intracellular GO:0005622 12133 9171 12 11 9983 11 1 false 0.39309710186685454 0.39309710186685454 0.0 negative_regulation_of_cell_proliferation GO:0008285 12133 455 12 1 2949 3 3 false 0.3952381623267501 0.3952381623267501 0.0 negative_regulation_of_catalytic_activity GO:0043086 12133 588 12 1 4970 4 3 false 0.39578215241966186 0.39578215241966186 0.0 regulation_of_protein_metabolic_process GO:0051246 12133 1388 12 3 5563 9 3 false 0.39793577614558295 0.39793577614558295 0.0 cellular_process GO:0009987 12133 9675 12 12 10446 12 1 false 0.3982837550876618 0.3982837550876618 0.0 receptor_signaling_protein_serine/threonine_kinase_activity GO:0004702 12133 299 12 1 750 1 3 false 0.39866666666682765 0.39866666666682765 3.090255244762607E-218 perinuclear_region_of_cytoplasm GO:0048471 12133 416 12 1 5117 6 1 false 0.3989144847528207 0.3989144847528207 0.0 cellular_protein_localization GO:0034613 12133 914 12 2 1438 2 2 false 0.4038325479118857 0.4038325479118857 0.0 ribonucleoprotein_complex_biogenesis GO:0022613 12133 243 12 1 1525 3 1 false 0.40612860030720577 0.40612860030720577 1.2095302863090285E-289 positive_regulation_of_transcription,_DNA-dependent GO:0045893 12133 931 12 3 2877 7 6 false 0.40691297694050943 0.40691297694050943 0.0 protein_heterodimerization_activity GO:0046982 12133 317 12 1 779 1 1 false 0.4069319640564945 0.4069319640564945 8.49214053182804E-228 positive_regulation_of_protein_phosphorylation GO:0001934 12133 550 12 1 1350 1 4 false 0.40740740740746606 0.40740740740746606 0.0 organic_substance_metabolic_process GO:0071704 12133 7451 12 12 8027 12 1 false 0.4089397093495515 0.4089397093495515 0.0 nuclear_chromatin GO:0000790 12133 151 12 1 368 1 2 false 0.41032608695653217 0.41032608695653217 1.5117378626822706E-107 stress-activated_MAPK_cascade GO:0051403 12133 207 12 1 504 1 2 false 0.41071428571427093 0.41071428571427093 1.7060805667457382E-147 regulation_of_protein_serine/threonine_kinase_activity GO:0071900 12133 375 12 1 912 1 2 false 0.4111842105262834 0.4111842105262834 2.059888800891414E-267 negative_regulation_of_RNA_metabolic_process GO:0051253 12133 760 12 3 3631 11 4 false 0.41353604513778525 0.41353604513778525 0.0 protein-DNA_complex_assembly GO:0065004 12133 126 12 1 538 2 2 false 0.4138854852444123 0.4138854852444123 1.6410350721824938E-126 regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0006357 12133 1197 12 4 2595 7 2 false 0.41569185014866206 0.41569185014866206 0.0 regulation_of_signal_transduction GO:0009966 12133 1603 12 1 3826 1 4 false 0.4189754312603047 0.4189754312603047 0.0 cellular_developmental_process GO:0048869 12133 2267 12 3 7817 8 2 false 0.422795033176004 0.422795033176004 0.0 DNA_recombination GO:0006310 12133 190 12 1 791 2 1 false 0.42293843716522367 0.42293843716522367 1.2250789605162758E-188 tRNA_aminoacylation GO:0043039 12133 44 12 1 104 1 2 false 0.42307692307691125 0.42307692307691125 2.147723813188652E-30 biological_process GO:0008150 12133 10446 12 12 11221 12 1 false 0.4234789797547981 0.4234789797547981 0.0 stress-activated_protein_kinase_signaling_cascade GO:0031098 12133 210 12 1 1631 4 2 false 0.4241306049152994 0.4241306049152994 3.3133814045702313E-271 induction_of_programmed_cell_death GO:0012502 12133 157 12 1 368 1 1 false 0.426630434782616 0.426630434782616 2.1106051638808005E-108 positive_regulation_of_intracellular_protein_kinase_cascade GO:0010740 12133 461 12 1 1079 1 3 false 0.42724745134375464 0.42724745134375464 5.98264E-319 Cajal_body GO:0015030 12133 46 12 1 272 3 1 false 0.42768251211919783 0.42768251211919783 3.189172863463676E-53 activation_of_innate_immune_response GO:0002218 12133 155 12 1 362 1 2 false 0.4281767955801526 0.4281767955801526 1.0665156090103768E-106 induction_of_apoptosis GO:0006917 12133 156 12 1 363 1 2 false 0.42975206611571753 0.42975206611571753 4.583372865169243E-107 macromolecule_catabolic_process GO:0009057 12133 820 12 2 6846 12 2 false 0.43053507001593216 0.43053507001593216 0.0 cellular_amino_acid_metabolic_process GO:0006520 12133 337 12 1 7342 12 3 false 0.4312294581219148 0.4312294581219148 0.0 regulation_of_transferase_activity GO:0051338 12133 667 12 1 2708 2 2 false 0.43201579798176304 0.43201579798176304 0.0 rRNA_processing GO:0006364 12133 102 12 1 231 1 3 false 0.4415584415584419 0.4415584415584419 2.6685808966337758E-68 intracellular_protein_kinase_cascade GO:0007243 12133 806 12 1 1813 1 1 false 0.444567015995786 0.444567015995786 0.0 cellular_response_to_stimulus GO:0051716 12133 4236 12 5 7871 8 2 false 0.44943710556723904 0.44943710556723904 0.0 cellular_component_biogenesis GO:0044085 12133 1525 12 3 3839 6 1 false 0.44995091629184497 0.44995091629184497 0.0 nuclear-transcribed_mRNA_catabolic_process,_nonsense-mediated_decay GO:0000184 12133 117 12 2 174 2 1 false 0.4508670520231076 0.4508670520231076 2.5039480990851377E-47 positive_regulation_of_nitrogen_compound_metabolic_process GO:0051173 12133 1126 12 3 5558 12 3 false 0.4508917079804948 0.4508917079804948 0.0 regulation_of_cell_death GO:0010941 12133 1062 12 2 6437 9 2 false 0.4517772971238541 0.4517772971238541 0.0 regulation_of_phosphate_metabolic_process GO:0019220 12133 1265 12 1 2780 1 2 false 0.45503597122260137 0.45503597122260137 0.0 transcription_initiation_from_RNA_polymerase_II_promoter GO:0006367 12133 195 12 1 1384 4 2 false 0.45565566019996295 0.45565566019996295 1.3395090025049634E-243 protein_transport GO:0015031 12133 1099 12 2 1627 2 2 false 0.45613346729693227 0.45613346729693227 0.0 positive_regulation_of_apoptotic_process GO:0043065 12133 362 12 1 1377 2 3 false 0.45681017885246766 0.45681017885246766 0.0 response_to_UV GO:0009411 12133 92 12 1 201 1 1 false 0.4577114427860681 0.4577114427860681 1.1329357256666295E-59 positive_regulation_of_macromolecule_metabolic_process GO:0010604 12133 1742 12 4 6129 12 3 false 0.4584436804335302 0.4584436804335302 0.0 cytosolic_small_ribosomal_subunit GO:0022627 12133 37 12 1 201 3 3 false 0.4586634665866414 0.4586634665866414 2.854176062301069E-41 positive_regulation_of_programmed_cell_death GO:0043068 12133 368 12 1 1393 2 3 false 0.4587056794640093 0.4587056794640093 0.0 proteolysis GO:0006508 12133 732 12 2 3431 7 1 false 0.4597970372867118 0.4597970372867118 0.0 negative_regulation_of_macromolecule_metabolic_process GO:0010605 12133 1253 12 3 6103 12 3 false 0.4604720569242199 0.4604720569242199 0.0 regulation_of_nitrogen_compound_metabolic_process GO:0051171 12133 3210 12 7 6094 12 2 false 0.46114488525853076 0.46114488525853076 0.0 nuclear_chromosome_part GO:0044454 12133 244 12 1 2878 7 3 false 0.4624970518513313 0.4624970518513313 0.0 mitochondrion GO:0005739 12133 1138 12 2 8213 11 2 false 0.46325295675865336 0.46325295675865336 0.0 regulation_of_RNA_metabolic_process GO:0051252 12133 2612 12 7 4544 11 3 false 0.46353829062468854 0.46353829062468854 0.0 regulation_of_phosphorylation GO:0042325 12133 845 12 1 1820 1 2 false 0.4642857142855993 0.4642857142855993 0.0 cell_part GO:0044464 12133 9983 12 11 10701 11 2 false 0.46563233096054285 0.46563233096054285 0.0 cell GO:0005623 12133 9984 12 11 10701 11 1 false 0.46614591319787263 0.46614591319787263 0.0 death GO:0016265 12133 1528 12 2 8052 8 1 false 0.4663302666836674 0.4663302666836674 0.0 positive_regulation_of_cell_differentiation GO:0045597 12133 439 12 1 3709 5 4 false 0.46752740109505536 0.46752740109505536 0.0 positive_regulation_of_cellular_process GO:0048522 12133 2811 12 4 9694 12 3 false 0.4764173027729113 0.4764173027729113 0.0 protein_complex_biogenesis GO:0070271 12133 746 12 2 1525 3 1 false 0.48376237140448075 0.48376237140448075 0.0 response_to_virus GO:0009615 12133 230 12 1 475 1 1 false 0.4842105263158639 0.4842105263158639 3.548520767075247E-142 macromolecular_complex_assembly GO:0065003 12133 973 12 3 1603 4 2 false 0.4872102465380391 0.4872102465380391 0.0 toll-like_receptor_10_signaling_pathway GO:0034166 12133 63 12 1 129 1 1 false 0.4883720930232628 0.4883720930232628 2.169508265339551E-38 innate_immune_response-activating_signal_transduction GO:0002758 12133 149 12 1 305 1 2 false 0.4885245901639539 0.4885245901639539 3.640759676212702E-91 regulation_of_kinase_activity GO:0043549 12133 654 12 1 1335 1 3 false 0.4898876404494377 0.4898876404494377 0.0 regulation_of_gene_expression GO:0010468 12133 2935 12 8 4361 11 2 false 0.49070137908166345 0.49070137908166345 0.0 positive_regulation_of_MAP_kinase_activity GO:0043406 12133 205 12 1 417 1 4 false 0.4916067146282839 0.4916067146282839 8.022991700655629E-125 positive_regulation_of_biological_process GO:0048518 12133 3081 12 4 10446 12 2 false 0.4918900074451903 0.4918900074451903 0.0 innate_immune_response GO:0045087 12133 626 12 1 1268 1 2 false 0.49369085173491006 0.49369085173491006 0.0 positive_regulation_of_developmental_process GO:0051094 12133 603 12 1 4731 5 3 false 0.4944087867634251 0.4944087867634251 0.0 positive_regulation_of_nucleobase-containing_compound_metabolic_process GO:0045935 12133 1108 12 3 5151 12 4 false 0.49466839613147906 0.49466839613147906 0.0 DNA-dependent_transcription,_initiation GO:0006352 12133 225 12 1 2751 8 2 false 0.4951671985738808 0.4951671985738808 0.0 toll-like_receptor_5_signaling_pathway GO:0034146 12133 64 12 1 129 1 1 false 0.4961240310077624 0.4961240310077624 2.1037655906323275E-38 positive_regulation_of_MAPK_cascade GO:0043410 12133 318 12 1 639 1 3 false 0.49765258215962105 0.49765258215962105 1.399157780258238E-191 positive_regulation_of_cellular_component_organization GO:0051130 12133 472 12 1 5027 7 3 false 0.49873393318665826 0.49873393318665826 0.0 DNA_biosynthetic_process GO:0071897 12133 268 12 1 3979 10 3 false 0.5024750537602749 0.5024750537602749 0.0 regulation_of_MAP_kinase_activity GO:0043405 12133 268 12 1 533 1 3 false 0.5028142589118941 0.5028142589118941 1.0382438249699724E-159 cotranslational_protein_targeting_to_membrane GO:0006613 12133 103 12 2 145 2 1 false 0.503160919540194 0.503160919540194 1.7288474062512548E-37 cell_death GO:0008219 12133 1525 12 2 7542 8 2 false 0.5032082315995817 0.5032082315995817 0.0 positive_regulation_of_biosynthetic_process GO:0009891 12133 1192 12 3 4582 10 3 false 0.5047690295467925 0.5047690295467925 0.0 nuclear_chromosome GO:0000228 12133 278 12 1 2899 7 3 false 0.5066019477937516 0.5066019477937516 0.0 intracellular_signal_transduction GO:0035556 12133 1813 12 1 3547 1 1 false 0.5111361714119392 0.5111361714119392 0.0 phosphorylation GO:0016310 12133 1421 12 1 2776 1 1 false 0.511887608069275 0.511887608069275 0.0 DNA_replication GO:0006260 12133 257 12 1 3702 10 3 false 0.5134431489920687 0.5134431489920687 0.0 positive_regulation_of_cellular_biosynthetic_process GO:0031328 12133 1174 12 3 4456 10 4 false 0.514556795649516 0.514556795649516 0.0 DNA_metabolic_process GO:0006259 12133 791 12 2 5627 12 2 false 0.5191243166577186 0.5191243166577186 0.0 positive_regulation_of_signaling GO:0023056 12133 817 12 1 4861 4 3 false 0.5211122278101669 0.5211122278101669 0.0 positive_regulation_of_cell_communication GO:0010647 12133 820 12 1 4819 4 3 false 0.5259032532493066 0.5259032532493066 0.0 mRNA_3'-UTR_binding GO:0003730 12133 20 12 1 91 3 1 false 0.5295303946989349 0.5295303946989349 1.5304206568397613E-20 regulation_of_protein_kinase_activity GO:0045859 12133 621 12 1 1169 1 3 false 0.5312232677504198 0.5312232677504198 0.0 positive_regulation_of_gene_expression GO:0010628 12133 1008 12 3 4103 11 3 false 0.5314990387361638 0.5314990387361638 0.0 positive_regulation_of_phosphorus_metabolic_process GO:0010562 12133 640 12 1 3702 4 3 false 0.5321271283419605 0.5321271283419605 0.0 regulation_of_transcription,_DNA-dependent GO:0006355 12133 2527 12 7 3120 8 4 false 0.5326773423692042 0.5326773423692042 0.0 MAP_kinase_activity GO:0004707 12133 277 12 1 520 1 2 false 0.5326923076922037 0.5326923076922037 2.5282679507054518E-155 response_to_oxygen_levels GO:0070482 12133 214 12 1 676 2 1 false 0.5332412886262115 0.5332412886262115 1.6255941364061853E-182 regulation_of_programmed_cell_death GO:0043067 12133 1031 12 2 1410 2 2 false 0.5345222455445995 0.5345222455445995 0.0 B_cell_homeostasis GO:0001782 12133 23 12 1 43 1 1 false 0.534883720930229 0.534883720930229 1.0410518840822442E-12 transcription_from_RNA_polymerase_II_promoter GO:0006366 12133 1365 12 4 2643 7 1 false 0.536004951807999 0.536004951807999 0.0 toll-like_receptor_TLR1:TLR2_signaling_pathway GO:0038123 12133 70 12 1 129 1 1 false 0.5426356589147338 0.5426356589147338 3.3394798770258706E-38 toll-like_receptor_TLR6:TLR2_signaling_pathway GO:0038124 12133 70 12 1 129 1 1 false 0.5426356589147338 0.5426356589147338 3.3394798770258706E-38 regulation_of_apoptotic_process GO:0042981 12133 1019 12 2 1381 2 2 false 0.5443136143732132 0.5443136143732132 0.0 regulation_of_protein_phosphorylation GO:0001932 12133 787 12 1 1444 1 3 false 0.545013850415557 0.545013850415557 0.0 extracellular_region_part GO:0044421 12133 740 12 1 10701 11 2 false 0.5455371388661205 0.5455371388661205 0.0 cellular_macromolecular_complex_assembly GO:0034622 12133 517 12 2 973 3 1 false 0.5470061758123461 0.5470061758123461 3.312522477266262E-291 positive_regulation_of_macromolecule_biosynthetic_process GO:0010557 12133 1091 12 3 3972 10 4 false 0.5471586214071261 0.5471586214071261 0.0 toll-like_receptor_9_signaling_pathway GO:0034162 12133 71 12 1 129 1 1 false 0.5503875968992259 0.5503875968992259 4.0186961232005657E-38 activation_of_MAPK_activity GO:0000187 12133 158 12 1 286 1 2 false 0.5524475524475345 0.5524475524475345 8.207976102051858E-85 chromosomal_part GO:0044427 12133 512 12 1 5337 8 2 false 0.5539753083416309 0.5539753083416309 0.0 regulation_of_sequence-specific_DNA_binding_transcription_factor_activity GO:0051090 12133 419 12 1 3842 7 3 false 0.5546967648734005 0.5546967648734005 0.0 cell_surface_receptor_signaling_pathway GO:0007166 12133 1975 12 1 3547 1 1 false 0.5568085706226186 0.5568085706226186 0.0 positive_regulation_of_immune_system_process GO:0002684 12133 540 12 1 3595 5 3 false 0.5570569714898044 0.5570569714898044 0.0 positive_regulation_of_RNA_metabolic_process GO:0051254 12133 979 12 3 3847 11 4 false 0.5588193172984803 0.5588193172984803 0.0 negative_regulation_of_cell_death GO:0060548 12133 567 12 1 3054 4 3 false 0.5604256726472451 0.5604256726472451 0.0 chromatin GO:0000785 12133 287 12 1 512 1 1 false 0.5605468749999285 0.5605468749999285 9.050120143931621E-152 nuclear_speck GO:0016607 12133 147 12 2 272 3 1 false 0.5607529604707322 0.5607529604707322 6.6218564870724965E-81 nucleotide-binding_oligomerization_domain_containing_signaling_pathway GO:0070423 12133 30 12 1 53 1 2 false 0.5660377358490526 0.5660377358490526 1.6040955778771873E-15 regulation_of_cellular_macromolecule_biosynthetic_process GO:2000112 12133 2758 12 8 3611 10 3 false 0.5672407814453286 0.5672407814453286 0.0 cellular_response_to_chemical_stimulus GO:0070887 12133 1604 12 2 4597 5 2 false 0.5695959955263019 0.5695959955263019 0.0 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter GO:0045944 12133 663 12 2 1546 4 3 false 0.5741323054626983 0.5741323054626983 0.0 immune_system_process GO:0002376 12133 1618 12 2 10446 12 1 false 0.5754972528456032 0.5754972528456032 0.0 immune_response-activating_cell_surface_receptor_signaling_pathway GO:0002429 12133 178 12 1 309 1 2 false 0.5760517799352067 0.5760517799352067 7.558729588417702E-91 regulation_of_nucleobase-containing_compound_metabolic_process GO:0019219 12133 3139 12 7 5532 12 4 false 0.5761402305652451 0.5761402305652451 0.0 regulation_of_response_to_stress GO:0080134 12133 674 12 1 3466 4 2 false 0.5791127248413666 0.5791127248413666 0.0 toll-like_receptor_2_signaling_pathway GO:0034134 12133 75 12 1 129 1 1 false 0.581395348837217 0.581395348837217 1.1512773005265922E-37 cytoskeleton_organization GO:0007010 12133 719 12 1 2031 2 1 false 0.5828131935301766 0.5828131935301766 0.0 regulatory_region_DNA_binding GO:0000975 12133 1169 12 2 2091 3 2 false 0.588223730942481 0.588223730942481 0.0 cytosolic_large_ribosomal_subunit GO:0022625 12133 51 12 1 200 3 3 false 0.5886447388457108 0.5886447388457108 7.491323649368413E-49 negative_regulation_of_molecular_function GO:0044092 12133 735 12 1 10257 12 2 false 0.5904772966055367 0.5904772966055367 0.0 negative_regulation_of_transcription,_DNA-dependent GO:0045892 12133 734 12 2 2771 7 5 false 0.5916411044813448 0.5916411044813448 0.0 activation_of_protein_kinase_activity GO:0032147 12133 247 12 1 417 1 1 false 0.5923261390887407 0.5923261390887407 9.475379918718814E-122 ribosome_biogenesis GO:0042254 12133 144 12 1 243 1 1 false 0.5925925925925675 0.5925925925925675 8.984879194471426E-71 mRNA_catabolic_process GO:0006402 12133 181 12 2 592 6 2 false 0.5931067730977487 0.5931067730977487 1.4563864024176219E-157 positive_regulation_of_catalytic_activity GO:0043085 12133 1023 12 1 5051 4 3 false 0.5956873932246204 0.5956873932246204 0.0 RNA_biosynthetic_process GO:0032774 12133 2751 12 8 4191 12 3 false 0.6020390885845402 0.6020390885845402 0.0 MyD88-independent_toll-like_receptor_signaling_pathway GO:0002756 12133 78 12 1 129 1 1 false 0.6046511627907161 0.6046511627907161 3.5310664374642874E-37 cellular_localization GO:0051641 12133 1845 12 2 7707 8 2 false 0.6060481842360519 0.6060481842360519 0.0 protein_stabilization GO:0050821 12133 60 12 1 99 1 1 false 0.6060606060605888 0.6060606060605888 1.818679918792965E-28 RNA_splicing,_via_transesterification_reactions GO:0000375 12133 207 12 3 307 4 1 false 0.6061709794352894 0.6061709794352894 1.4733469150792184E-83 regulation_of_MAPK_cascade GO:0043408 12133 429 12 1 701 1 2 false 0.6119828815976278 0.6119828815976278 1.5434745144062482E-202 cullin-RING_ubiquitin_ligase_complex GO:0031461 12133 90 12 1 147 1 1 false 0.6122448979591654 0.6122448979591654 3.485982605742994E-42 regulation_of_cell_cycle GO:0051726 12133 659 12 1 6583 9 2 false 0.6132268547295547 0.6132268547295547 0.0 regulation_of_catalytic_activity GO:0050790 12133 1692 12 2 6953 8 3 false 0.6162553380203755 0.6162553380203755 0.0 MyD88-dependent_toll-like_receptor_signaling_pathway GO:0002755 12133 80 12 1 129 1 1 false 0.6201550387596937 0.6201550387596937 8.751505837166389E-37 MAPK_cascade GO:0000165 12133 502 12 1 806 1 1 false 0.6228287841190995 0.6228287841190995 3.7900857366173457E-231 protein_oligomerization GO:0051259 12133 288 12 1 743 2 1 false 0.6253079052289092 0.6253079052289092 1.196705520432063E-214 negative_regulation_of_programmed_cell_death GO:0043069 12133 544 12 1 1399 2 3 false 0.6266646623730255 0.6266646623730255 0.0 negative_regulation_of_apoptotic_process GO:0043066 12133 537 12 1 1377 2 3 false 0.6280463089635778 0.6280463089635778 0.0 antigen_receptor-mediated_signaling_pathway GO:0050851 12133 112 12 1 178 1 1 false 0.629213483146089 0.629213483146089 1.7238002808689451E-50 U5_snRNP GO:0005682 12133 80 12 3 93 3 1 false 0.6331396513724712 0.6331396513724712 3.852654648545616E-16 protein_homooligomerization GO:0051260 12133 183 12 1 288 1 1 false 0.635416666666655 0.635416666666655 1.8197847122731807E-81 toll-like_receptor_3_signaling_pathway GO:0034138 12133 82 12 1 129 1 1 false 0.635658914728704 0.635658914728704 2.4714073881998435E-36 negative_regulation_of_cellular_process GO:0048523 12133 2515 12 3 9689 12 3 false 0.6385240283348741 0.6385240283348741 0.0 carboxylic_acid_metabolic_process GO:0019752 12133 614 12 1 7453 12 2 false 0.6438834664494587 0.6438834664494587 0.0 negative_regulation_of_biological_process GO:0048519 12133 2732 12 3 10446 12 2 false 0.6443291097245927 0.6443291097245927 0.0 tRNA_metabolic_process GO:0006399 12133 104 12 1 258 2 1 false 0.6446475432087663 0.6446475432087663 5.594663773224907E-75 positive_regulation_of_protein_modification_process GO:0031401 12133 708 12 1 2417 3 3 false 0.6466763284519015 0.6466763284519015 0.0 cellular_component_morphogenesis GO:0032989 12133 810 12 1 5068 6 4 false 0.6484641760688822 0.6484641760688822 0.0 homeostatic_process GO:0042592 12133 990 12 2 2082 4 1 false 0.6500478807149102 0.6500478807149102 0.0 cellular_protein_complex_assembly GO:0043623 12133 284 12 1 958 3 2 false 0.6522165633484798 0.6522165633484798 4.57678794545446E-252 cellular_protein_metabolic_process GO:0044267 12133 3038 12 6 5899 12 2 false 0.6528840848176181 0.6528840848176181 0.0 negative_regulation_of_biosynthetic_process GO:0009890 12133 930 12 2 4429 10 3 false 0.6538590196791891 0.6538590196791891 0.0 rRNA_metabolic_process GO:0016072 12133 107 12 1 258 2 1 false 0.6584019545741964 0.6584019545741964 1.860360860420455E-75 negative_regulation_of_cellular_biosynthetic_process GO:0031327 12133 916 12 2 4298 10 4 false 0.6628082001744945 0.6628082001744945 0.0 cytoplasmic_part GO:0044444 12133 5117 12 6 9083 11 2 false 0.6671020379814059 0.6671020379814059 0.0 organelle_organization GO:0006996 12133 2031 12 2 7663 8 2 false 0.6693841325304141 0.6693841325304141 0.0 regulation_of_immune_system_process GO:0002682 12133 794 12 1 6789 9 2 false 0.6737540505307185 0.6737540505307185 0.0 response_to_radiation GO:0009314 12133 293 12 1 676 2 1 false 0.6793644532109588 0.6793644532109588 4.1946042901139895E-200 regulation_of_alternative_mRNA_splicing,_via_spliceosome GO:0000381 12133 16 12 1 37 2 2 false 0.6846846846846875 0.6846846846846875 7.76652299088412E-11 response_to_light_stimulus GO:0009416 12133 201 12 1 293 1 1 false 0.6860068259385791 0.6860068259385791 1.3130246435910127E-78 organic_acid_metabolic_process GO:0006082 12133 676 12 1 7326 12 2 false 0.6873498757732055 0.6873498757732055 0.0 protein_serine/threonine_kinase_activity GO:0004674 12133 709 12 1 1014 1 1 false 0.6992110453650483 0.6992110453650483 1.8231541307779663E-268 endoplasmic_reticulum GO:0005783 12133 854 12 1 8213 11 2 false 0.7013593182802278 0.7013593182802278 0.0 negative_regulation_of_macromolecule_biosynthetic_process GO:0010558 12133 862 12 2 3780 10 4 false 0.703207759397529 0.703207759397529 0.0 vesicle GO:0031982 12133 834 12 1 7980 11 1 false 0.703304020037065 0.703304020037065 0.0 small_ribosomal_subunit GO:0015935 12133 60 12 1 132 2 1 false 0.7043719639139102 0.7043719639139102 4.556510204279982E-39 negative_regulation_of_gene_expression GO:0010629 12133 817 12 2 3906 11 3 false 0.7045559146582255 0.7045559146582255 0.0 identical_protein_binding GO:0042802 12133 743 12 1 6397 10 1 false 0.7093350669838343 0.7093350669838343 0.0 extracellular_region GO:0005576 12133 1152 12 1 10701 11 1 false 0.7145044475602784 0.7145044475602784 0.0 immune_response GO:0006955 12133 1006 12 1 5335 6 2 false 0.7147438645747346 0.7147438645747346 0.0 single-organism_transport GO:0044765 12133 2323 12 2 8134 8 2 false 0.7152758109214721 0.7152758109214721 0.0 regulation_of_molecular_function GO:0065009 12133 2079 12 2 10494 12 2 false 0.7198973678535038 0.7198973678535038 0.0 regulation_of_cell_differentiation GO:0045595 12133 872 12 1 6612 9 3 false 0.7201973151176109 0.7201973151176109 0.0 positive_regulation_of_response_to_stimulus GO:0048584 12133 1111 12 1 5778 6 3 false 0.7224808257464981 0.7224808257464981 0.0 regulation_of_RNA_biosynthetic_process GO:2001141 12133 2562 12 7 3220 9 4 false 0.7268000677744532 0.7268000677744532 0.0 protein_dimerization_activity GO:0046983 12133 779 12 1 6397 10 1 false 0.7273347624411985 0.7273347624411985 0.0 interspecies_interaction_between_organisms GO:0044419 12133 417 12 1 1180 3 1 false 0.7300253025101386 0.7300253025101386 0.0 transferase_activity,_transferring_phosphorus-containing_groups GO:0016772 12133 1304 12 1 1779 1 1 false 0.7329960652055553 0.7329960652055553 0.0 negative_regulation_of_cellular_macromolecule_biosynthetic_process GO:2000113 12133 829 12 2 3453 10 4 false 0.7332928878674695 0.7332928878674695 0.0 molecular_transducer_activity GO:0060089 12133 1070 12 1 10257 12 1 false 0.733612036703184 0.733612036703184 0.0 ATP_binding GO:0005524 12133 1212 12 1 1638 1 3 false 0.739926739926079 0.739926739926079 0.0 intracellular_membrane-bounded_organelle GO:0043231 12133 7259 12 10 7976 11 2 false 0.7403636785390229 0.7403636785390229 0.0 nucleic_acid_binding_transcription_factor_activity GO:0001071 12133 1113 12 1 10311 12 3 false 0.746268272777965 0.746268272777965 0.0 adenyl_ribonucleotide_binding GO:0032559 12133 1231 12 1 1645 1 2 false 0.748328267477667 0.748328267477667 0.0 adenyl_nucleotide_binding GO:0030554 12133 1235 12 1 1650 1 1 false 0.748484848485394 0.748484848485394 0.0 membrane-bounded_organelle GO:0043227 12133 7284 12 10 7980 11 1 false 0.7516882124147775 0.7516882124147775 0.0 response_to_chemical_stimulus GO:0042221 12133 2369 12 2 5200 5 1 false 0.7521741066725567 0.7521741066725567 0.0 protein_kinase_activity GO:0004672 12133 1014 12 1 1347 1 3 false 0.7527839643658618 0.7527839643658618 0.0 chromosome GO:0005694 12133 592 12 1 3226 7 1 false 0.7584408431954257 0.7584408431954257 0.0 kinase_activity GO:0016301 12133 1174 12 1 1546 1 2 false 0.7593790426910867 0.7593790426910867 0.0 cell_proliferation GO:0008283 12133 1316 12 1 8052 8 1 false 0.7602871865479504 0.7602871865479504 0.0 anion_binding GO:0043168 12133 2280 12 1 4448 2 1 false 0.7624876038034372 0.7624876038034372 0.0 protein_localization GO:0008104 12133 1434 12 2 1642 2 1 false 0.7626295127663042 0.7626295127663042 3.426309620265761E-270 JNK_cascade GO:0007254 12133 159 12 1 207 1 1 false 0.7681159420289673 0.7681159420289673 3.1556682987155503E-48 nucleotide_binding GO:0000166 12133 1997 12 5 2103 5 2 false 0.7719411355355333 0.7719411355355333 1.0169073992212018E-181 cell_cycle GO:0007049 12133 1295 12 1 7541 8 1 false 0.7786651842005459 0.7786651842005459 0.0 lymphocyte_homeostasis GO:0002260 12133 43 12 1 55 1 1 false 0.7818181818181777 0.7818181818181777 2.27930752242823E-12 response_to_other_organism GO:0051707 12133 475 12 1 1194 3 2 false 0.7820025244504847 0.7820025244504847 0.0 plasma_membrane_part GO:0044459 12133 1329 12 1 10213 11 3 false 0.7843957750275841 0.7843957750275841 0.0 regulation_of_cell_proliferation GO:0042127 12133 999 12 1 6358 9 2 false 0.7855084189598207 0.7855084189598207 0.0 T_cell_receptor_signaling_pathway GO:0050852 12133 88 12 1 112 1 1 false 0.7857142857143178 0.7857142857143178 5.828412725788921E-25 transcription,_DNA-dependent GO:0006351 12133 2643 12 7 4063 12 3 false 0.7886833321154367 0.7886833321154367 0.0 toll-like_receptor_4_signaling_pathway GO:0034142 12133 102 12 1 129 1 1 false 0.7906976744186143 0.7906976744186143 2.104544859412626E-28 positive_regulation_of_NF-kappaB_transcription_factor_activity GO:0051092 12133 247 12 1 312 1 1 false 0.7916666666666485 0.7916666666666485 8.216510305576978E-69 intrinsic_to_membrane GO:0031224 12133 2375 12 1 2995 1 1 false 0.792988313854418 0.792988313854418 0.0 cellular_nitrogen_compound_catabolic_process GO:0044270 12133 1246 12 2 5462 12 2 false 0.7969537671830205 0.7969537671830205 0.0 organic_cyclic_compound_catabolic_process GO:1901361 12133 1265 12 2 5528 12 2 false 0.7985576699959025 0.7985576699959025 0.0 response_to_stimulus GO:0050896 12133 5200 12 5 10446 12 1 false 0.8020053392284008 0.8020053392284008 0.0 large_ribosomal_subunit GO:0015934 12133 73 12 1 132 2 1 false 0.8021050196622272 0.8021050196622272 5.5437540818743186E-39 heterocycle_catabolic_process GO:0046700 12133 1243 12 2 5392 12 2 false 0.8023380460851989 0.8023380460851989 0.0 protein_modification_by_small_protein_conjugation GO:0032446 12133 578 12 2 645 2 1 false 0.802893735856127 0.802893735856127 7.3138241320053254E-93 positive_regulation_of_molecular_function GO:0044093 12133 1303 12 1 10257 12 2 false 0.8043166726012745 0.8043166726012745 0.0 aromatic_compound_catabolic_process GO:0019439 12133 1249 12 2 5388 12 2 false 0.8051665910824224 0.8051665910824224 0.0 positive_regulation_of_cellular_protein_metabolic_process GO:0032270 12133 789 12 1 3771 7 4 false 0.8069290174347205 0.8069290174347205 0.0 positive_regulation_of_protein_metabolic_process GO:0051247 12133 853 12 1 4044 7 3 false 0.8098019718843072 0.8098019718843072 0.0 developmental_process GO:0032502 12133 3447 12 3 10446 12 1 false 0.8125580492484712 0.8125580492484712 0.0 regulation_of_developmental_process GO:0050793 12133 1233 12 1 7209 9 2 false 0.8153402638079963 0.8153402638079963 0.0 regulation_of_cellular_component_organization GO:0051128 12133 1152 12 1 7336 10 2 false 0.819030727386254 0.819030727386254 0.0 enzyme_binding GO:0019899 12133 1005 12 1 6397 10 1 false 0.8192137960100103 0.8192137960100103 0.0 ubiquitin-protein_ligase_activity GO:0004842 12133 321 12 1 558 2 2 false 0.8200420841298715 0.8200420841298715 1.7708856343357755E-164 single-organism_developmental_process GO:0044767 12133 2776 12 2 8064 8 2 false 0.8223447905621208 0.8223447905621208 0.0 programmed_cell_death GO:0012501 12133 1385 12 2 1525 2 1 false 0.8247665763094012 0.8247665763094012 2.142172117700311E-202 membrane_protein_ectodomain_proteolysis GO:0006509 12133 33 12 1 40 1 1 false 0.8250000000000103 0.8250000000000103 5.363782453565752E-8 response_to_wounding GO:0009611 12133 905 12 1 2540 4 1 false 0.8285380944863356 0.8285380944863356 0.0 protein_complex_assembly GO:0006461 12133 743 12 2 1214 4 3 false 0.8347567227229449 0.8347567227229449 0.0 phosphotransferase_activity,_alcohol_group_as_acceptor GO:0016773 12133 1089 12 1 1304 1 1 false 0.8351226993861972 0.8351226993861972 1.004636319027547E-252 transferase_activity GO:0016740 12133 1779 12 1 4901 4 1 false 0.8354531270510828 0.8354531270510828 0.0 nucleobase-containing_compound_catabolic_process GO:0034655 12133 1220 12 2 4878 12 5 false 0.8421421426513098 0.8421421426513098 0.0 small_molecule_metabolic_process GO:0044281 12133 2423 12 1 2877 1 1 false 0.842196732708071 0.842196732708071 0.0 protein_phosphorylation GO:0006468 12133 1195 12 1 2577 3 2 false 0.8459210545448961 0.8459210545448961 0.0 immune_response-activating_signal_transduction GO:0002757 12133 299 12 1 352 1 2 false 0.849431818181766 0.849431818181766 2.8561568566531905E-64 cation_binding GO:0043169 12133 2758 12 1 4448 2 1 false 0.8556939809108554 0.8556939809108554 0.0 erythrocyte_homeostasis GO:0034101 12133 95 12 1 111 1 1 false 0.8558558558558544 0.8558558558558544 1.225965890705918E-19 organ_development GO:0048513 12133 1929 12 1 3099 2 2 false 0.8575385424942442 0.8575385424942442 0.0 cell_differentiation GO:0030154 12133 2154 12 3 2267 3 1 false 0.8577334829750434 0.8577334829750434 2.602261335719434E-194 cellular_component_organization GO:0016043 12133 3745 12 6 3839 6 1 false 0.8617070095778504 0.8617070095778504 4.153510440731863E-191 anatomical_structure_morphogenesis GO:0009653 12133 1664 12 1 3447 3 2 false 0.8617143295671161 0.8617143295671161 0.0 single-organism_cellular_process GO:0044763 12133 7541 12 8 9888 12 2 false 0.8674711168811969 0.8674711168811969 0.0 ncRNA_processing GO:0034470 12133 186 12 1 649 6 2 false 0.8693956013541306 0.8693956013541306 4.048832162241149E-168 defense_response GO:0006952 12133 1018 12 1 2540 4 1 false 0.8712827579462472 0.8712827579462472 0.0 catabolic_process GO:0009056 12133 2164 12 2 8027 12 1 false 0.8750098041376018 0.8750098041376018 0.0 cellular_catabolic_process GO:0044248 12133 1972 12 2 7289 12 2 false 0.8764890479724983 0.8764890479724983 0.0 establishment_of_localization GO:0051234 12133 2833 12 2 10446 12 2 false 0.8774277118636356 0.8774277118636356 0.0 toll-like_receptor_signaling_pathway GO:0002224 12133 129 12 1 147 1 1 false 0.8775510204081407 0.8775510204081407 1.843896992838607E-23 organic_substance_catabolic_process GO:1901575 12133 2054 12 2 7502 12 2 false 0.8813496849697211 0.8813496849697211 0.0 single-organism_process GO:0044699 12133 8052 12 8 10446 12 1 false 0.8824032680738109 0.8824032680738109 0.0 catalytic_activity GO:0003824 12133 4901 12 4 10478 12 2 false 0.8906284811676917 0.8906284811676917 0.0 cellular_component GO:0005575 12133 10701 12 11 11221 12 1 false 0.8959188136196365 0.8959188136196365 0.0 regulation_of_phosphorus_metabolic_process GO:0051174 12133 1277 12 1 5183 8 2 false 0.896141908983708 0.896141908983708 0.0 cellular_response_to_organic_substance GO:0071310 12133 1347 12 1 1979 2 2 false 0.8981234202799068 0.8981234202799068 0.0 protein_ubiquitination GO:0016567 12133 548 12 2 578 2 1 false 0.8988024203465327 0.8988024203465327 7.913703273197485E-51 regulatory_region_nucleic_acid_binding GO:0001067 12133 1169 12 2 2849 8 1 false 0.9043157887429909 0.9043157887429909 0.0 regulation_of_multicellular_organismal_process GO:0051239 12133 1532 12 1 6622 9 1 false 0.9064925678149922 0.9064925678149922 0.0 cytoplasm GO:0005737 12133 6938 12 7 9083 11 1 false 0.9064995215176022 0.9064995215176022 0.0 SRP-dependent_cotranslational_protein_targeting_to_membrane GO:0006614 12133 101 12 2 106 2 2 false 0.9074573225516511 0.9074573225516511 9.867686559172291E-9 membrane-bounded_vesicle GO:0031988 12133 762 12 1 834 1 1 false 0.9136690647483704 0.9136690647483704 6.820230733401612E-106 regulation_of_protein_modification_process GO:0031399 12133 1001 12 1 2566 5 2 false 0.9158209098604178 0.9158209098604178 0.0 sequence-specific_DNA_binding GO:0043565 12133 1189 12 1 2091 3 1 false 0.9198810813532322 0.9198810813532322 0.0 macromolecule_modification GO:0043412 12133 2461 12 3 6052 12 1 false 0.923597433819661 0.923597433819661 0.0 nuclear-transcribed_mRNA_catabolic_process GO:0000956 12133 174 12 2 181 2 1 false 0.9239410681399386 0.9239410681399386 8.905994863592909E-13 centrosome_organization GO:0051297 12133 61 12 1 66 1 1 false 0.924242424242419 0.924242424242419 1.1189527318559458E-7 acid-amino_acid_ligase_activity GO:0016881 12133 351 12 1 379 1 1 false 0.9261213720316644 0.9261213720316644 5.324332733169013E-43 interaction_with_host GO:0051701 12133 387 12 1 417 1 2 false 0.9280575539568932 0.9280575539568932 1.9217516081652173E-46 RNA_splicing,_via_transesterification_reactions_with_bulged_adenosine_as_nucleophile GO:0000377 12133 202 12 3 207 3 1 false 0.9289364316185182 0.9289364316185182 3.3148479610294504E-10 cellular_protein_complex_disassembly GO:0043624 12133 149 12 2 154 2 1 false 0.9359137594431084 0.9359137594431084 1.4793035521715585E-9 protein_complex GO:0043234 12133 2976 12 5 3462 7 1 false 0.9377906032745846 0.9377906032745846 0.0 virus-host_interaction GO:0019048 12133 355 12 1 588 3 2 false 0.9382633808911776 0.9382633808911776 1.0104535019427035E-170 ligase_activity,_forming_carbon-nitrogen_bonds GO:0016879 12133 379 12 1 504 2 1 false 0.9388589100321431 0.9388589100321431 6.011520399617331E-122 response_to_organic_substance GO:0010033 12133 1783 12 1 2369 2 1 false 0.9388907824036242 0.9388907824036242 0.0 regulation_of_signaling GO:0023051 12133 1793 12 1 6715 9 2 false 0.9390447213472444 0.9390447213472444 0.0 hemopoiesis GO:0030097 12133 462 12 1 491 1 1 false 0.9409368635436436 0.9409368635436436 1.8682876304369947E-47 response_to_decreased_oxygen_levels GO:0036293 12133 202 12 1 214 1 1 false 0.9439252336448956 0.9439252336448956 7.108512362452622E-20 localization GO:0051179 12133 3467 12 2 10446 12 1 false 0.9450419163246675 0.9450419163246675 0.0 cell_morphogenesis GO:0000902 12133 766 12 1 810 1 1 false 0.9456790123456539 0.9456790123456539 9.285456073507826E-74 regulation_of_cell_communication GO:0010646 12133 1796 12 1 6469 9 2 false 0.9465561401385203 0.9465561401385203 0.0 hydrolase_activity GO:0016787 12133 2556 12 1 4901 4 1 false 0.947657720654976 0.947657720654976 0.0 regulation_of_response_to_stimulus GO:0048583 12133 2074 12 1 7292 9 2 false 0.9509020078780193 0.9509020078780193 0.0 small_conjugating_protein_ligase_activity GO:0019787 12133 335 12 1 351 1 1 false 0.9544159544159461 0.9544159544159461 5.577217121688537E-28 protein_modification_process GO:0036211 12133 2370 12 3 3518 7 2 false 0.9588028475543475 0.9588028475543475 0.0 plasma_membrane GO:0005886 12133 2594 12 1 10252 11 3 false 0.9596740536595829 0.9596740536595829 0.0 TRIF-dependent_toll-like_receptor_signaling_pathway GO:0035666 12133 75 12 1 78 1 1 false 0.961538461538445 0.961538461538445 1.3144749986854762E-5 transport GO:0006810 12133 2783 12 2 2833 2 1 false 0.9650070995385234 0.9650070995385234 1.147202604491021E-108 system_development GO:0048731 12133 2686 12 1 3304 2 2 false 0.9650598289517768 0.9650598289517768 0.0 organonitrogen_compound_metabolic_process GO:1901564 12133 1841 12 1 7461 12 2 false 0.9667331781032861 0.9667331781032861 0.0 cell_periphery GO:0071944 12133 2667 12 1 9983 11 1 false 0.9673212135489936 0.9673212135489936 0.0 single-multicellular_organism_process GO:0044707 12133 4095 12 2 8057 8 2 false 0.9683725270204336 0.9683725270204336 0.0 anatomical_structure_development GO:0048856 12133 3099 12 2 3447 3 1 false 0.9715439180591157 0.9715439180591157 0.0 membrane_part GO:0044425 12133 2995 12 1 10701 11 2 false 0.9730485071301581 0.9730485071301581 0.0 membrane GO:0016020 12133 4398 12 2 10701 11 1 false 0.9743732946989236 0.9743732946989236 0.0 integral_to_membrane GO:0016021 12133 2318 12 1 2375 1 1 false 0.9760000000014666 0.9760000000014666 3.0839384482043954E-116 cellular_protein_modification_process GO:0006464 12133 2370 12 3 3038 6 2 false 0.976263974894517 0.976263974894517 0.0 metal_ion_binding GO:0046872 12133 2699 12 1 2758 1 1 false 0.9786076867315662 0.9786076867315662 2.6200760259069314E-123 multicellular_organismal_process GO:0032501 12133 4223 12 2 10446 12 1 false 0.9817810789141936 0.9817810789141936 0.0 apoptotic_process GO:0006915 12133 1373 12 2 1385 2 1 false 0.9827403434810396 0.9827403434810396 1.0085392941984968E-29 sequence-specific_DNA_binding_transcription_factor_activity GO:0003700 12133 1112 12 1 2528 7 3 false 0.9828144528322222 0.9828144528322222 0.0 nucleoside_binding GO:0001882 12133 1639 12 1 4455 9 3 false 0.983966862822092 0.983966862822092 0.0 purine_ribonucleoside_triphosphate_binding GO:0035639 12133 1477 12 1 2560 5 2 false 0.9865220375346399 0.9865220375346399 0.0 pattern_recognition_receptor_signaling_pathway GO:0002221 12133 147 12 1 149 1 1 false 0.9865771812081086 0.9865771812081086 9.06947215672054E-5 oxoacid_metabolic_process GO:0043436 12133 667 12 1 676 1 1 false 0.9866863905329417 0.9866863905329417 1.2985791548492531E-20 purine_ribonucleotide_binding GO:0032555 12133 1641 12 1 1660 1 2 false 0.9885542168674124 0.9885542168674124 8.870449707822982E-45 phosphate-containing_compound_metabolic_process GO:0006796 12133 2776 12 1 2805 1 1 false 0.9896613190735933 0.9896613190735933 1.0460685646312495E-69 multicellular_organismal_development GO:0007275 12133 3069 12 1 4373 4 2 false 0.9921188714018435 0.9921188714018435 0.0 transcription_regulatory_region_sequence-specific_DNA_binding GO:0000976 12133 1120 12 1 1225 2 2 false 0.9927170868348872 0.9927170868348872 5.928244845001387E-155 DNA_binding GO:0003677 12133 2091 12 3 2849 8 1 false 0.9941372362563416 0.9941372362563416 0.0 single_organism_signaling GO:0044700 12133 3878 12 1 8052 8 2 false 0.9948026132546941 0.9948026132546941 0.0 purine_nucleoside_binding GO:0001883 12133 1631 12 1 1639 1 1 false 0.9951189749860739 0.9951189749860739 7.876250956196666E-22 single-organism_metabolic_process GO:0044710 12133 2877 12 1 8027 12 1 false 0.9951577153674541 0.9951577153674541 0.0 viral_reproduction GO:0016032 12133 633 12 3 634 3 1 false 0.9952681388015118 0.9952681388015118 0.0015772870662463625 signaling GO:0023052 12133 3878 12 1 10446 12 1 false 0.9961965668500733 0.9961965668500733 0.0 purine_ribonucleoside_binding GO:0032550 12133 1629 12 1 1635 1 2 false 0.996330275229448 0.996330275229448 3.803774675047802E-17 ribonucleoside_binding GO:0032549 12133 1633 12 1 1639 1 1 false 0.9963392312390289 0.9963392312390289 3.7483303336303164E-17 ion_binding GO:0043167 12133 4448 12 2 8962 12 1 false 0.9965979330383836 0.9965979330383836 0.0 phosphorus_metabolic_process GO:0006793 12133 2805 12 1 7256 12 1 false 0.9971775197363106 0.9971775197363106 0.0 cell_communication GO:0007154 12133 3962 12 1 7541 8 1 false 0.9974362533535484 0.9974362533535484 0.0 signal_transduction GO:0007165 12133 3547 12 1 6702 9 4 false 0.9988714304828363 0.9988714304828363 0.0 purine_nucleotide_binding GO:0017076 12133 1650 12 1 1997 5 1 false 0.9998453452441327 0.9998453452441327 0.0 ribonucleotide_binding GO:0032553 12133 1651 12 1 1997 5 1 false 0.9998475736989426 0.9998475736989426 0.0 GO:0000000 12133 11221 12 12 0 0 0 true 1.0 1.0 1.0 aminoacyl-tRNA_ligase_activity GO:0004812 12133 39 12 1 39 1 1 true 1.0 1.0 1.0 ligase_activity,_forming_aminoacyl-tRNA_and_related_compounds GO:0016876 12133 39 12 1 39 1 1 true 1.0 1.0 1.0 transcription_regulatory_region_DNA_binding GO:0044212 12133 1169 12 2 1169 2 1 true 1.0 1.0 1.0 symbiosis,_encompassing_mutualism_through_parasitism GO:0044403 12133 417 12 1 417 1 1 true 1.0 1.0 1.0