Functional 5' UTR Motif Discovery with LESMoN: Local Enrichment of Sequence Motifs in Biological Networks

Mathieu Lavallee-Adam, Philippe Cloutier, Benoit Coulombe, Mathieu Blanchette

Java Program (with documentation and example input and output files) implementing an algorithm identifying sequence motifs for which the associated proteins are significantly clustered in a given protein-protein interaction network: LESMoN

The MathUtils.java of the org.apache.commons.math.util was downloaded from the apache project website.

Supporting Material


Access all results from Ontologizer for the motifs identified by LESMoN
This folder contains the GO enrichment analysis result files produced by Ontologizer for the proteins associated to the 1873 motifs that obtained a clustering p-value < 10-6. Motifs are indicated in the file names.

Access all results from Ontologizer for the motifs identified by the MCL+MEME alternative method
This folder contains the GO enrichment analysis result files produced by Ontologizer for the proteins associated to the 9 motifs that obtained a MEME E-value < 1. Motifs are indicated in the file names.

If you have questions about executing the program, feel free to email us at mathieu.lavallee-adam@mail.mcgill.ca